Amino acid dipepetide frequency for Gyrovirus GyV8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.463AlaAla: 2.463 ± 2.277
1.232AlaCys: 1.232 ± 0.705
4.926AlaAsp: 4.926 ± 4.0
2.463AlaGlu: 2.463 ± 2.277
2.463AlaPhe: 2.463 ± 1.41
1.232AlaGly: 1.232 ± 0.705
1.232AlaHis: 1.232 ± 1.904
2.463AlaIle: 2.463 ± 0.697
1.232AlaLys: 1.232 ± 1.139
3.695AlaLeu: 3.695 ± 1.506
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
3.695AlaPro: 3.695 ± 1.506
3.695AlaGln: 3.695 ± 1.506
4.926AlaArg: 4.926 ± 2.871
6.158AlaSer: 6.158 ± 1.345
3.695AlaThr: 3.695 ± 2.115
4.926AlaVal: 4.926 ± 1.755
1.232AlaTrp: 1.232 ± 1.139
1.232AlaTyr: 1.232 ± 0.705
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.232CysAsp: 1.232 ± 0.705
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.232CysLeu: 1.232 ± 0.705
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.232CysGln: 1.232 ± 1.904
2.463CysArg: 2.463 ± 0.697
2.463CysSer: 2.463 ± 2.277
1.232CysThr: 1.232 ± 1.139
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.232CysTyr: 1.232 ± 0.705
0.0CysXaa: 0.0 ± 0.0
Asp
1.232AspAla: 1.232 ± 0.705
0.0AspCys: 0.0 ± 0.0
4.926AspAsp: 4.926 ± 4.0
2.463AspGlu: 2.463 ± 1.41
2.463AspPhe: 2.463 ± 0.697
3.695AspGly: 3.695 ± 3.047
0.0AspHis: 0.0 ± 0.0
3.695AspIle: 3.695 ± 3.414
2.463AspLys: 2.463 ± 0.697
6.158AspLeu: 6.158 ± 3.894
2.463AspMet: 2.463 ± 2.277
3.695AspAsn: 3.695 ± 2.115
6.158AspPro: 6.158 ± 2.41
0.0AspGln: 0.0 ± 0.0
1.232AspArg: 1.232 ± 1.139
2.463AspSer: 2.463 ± 1.565
7.389AspThr: 7.389 ± 2.09
1.232AspVal: 1.232 ± 1.139
1.232AspTrp: 1.232 ± 0.705
2.463AspTyr: 2.463 ± 2.277
0.0AspXaa: 0.0 ± 0.0
Glu
1.232GluAla: 1.232 ± 1.139
1.232GluCys: 1.232 ± 1.139
4.926GluAsp: 4.926 ± 1.393
2.463GluGlu: 2.463 ± 2.277
1.232GluPhe: 1.232 ± 0.705
3.695GluGly: 3.695 ± 3.416
1.232GluHis: 1.232 ± 0.705
2.463GluIle: 2.463 ± 0.697
2.463GluLys: 2.463 ± 0.697
2.463GluLeu: 2.463 ± 2.271
0.0GluMet: 0.0 ± 0.0
1.232GluAsn: 1.232 ± 0.705
1.232GluPro: 1.232 ± 1.139
1.232GluGln: 1.232 ± 1.139
1.232GluArg: 1.232 ± 0.705
2.463GluSer: 2.463 ± 1.565
2.463GluThr: 2.463 ± 1.41
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
3.695GluTyr: 3.695 ± 1.635
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.232PheCys: 1.232 ± 0.705
3.695PheAsp: 3.695 ± 0.817
0.0PheGlu: 0.0 ± 0.0
3.695PhePhe: 3.695 ± 0.817
3.695PheGly: 3.695 ± 0.817
0.0PheHis: 0.0 ± 0.0
1.232PheIle: 1.232 ± 0.705
3.695PheLys: 3.695 ± 1.751
4.926PheLeu: 4.926 ± 1.358
1.232PheMet: 1.232 ± 1.394
3.695PheAsn: 3.695 ± 2.115
8.621PhePro: 8.621 ± 4.935
1.232PheGln: 1.232 ± 0.705
4.926PheArg: 4.926 ± 1.358
2.463PheSer: 2.463 ± 0.697
1.232PheThr: 1.232 ± 1.139
1.232PheVal: 1.232 ± 0.705
0.0PheTrp: 0.0 ± 0.0
2.463PheTyr: 2.463 ± 1.41
0.0PheXaa: 0.0 ± 0.0
Gly
2.463GlyAla: 2.463 ± 0.697
0.0GlyCys: 0.0 ± 0.0
3.695GlyAsp: 3.695 ± 1.751
2.463GlyGlu: 2.463 ± 0.697
2.463GlyPhe: 2.463 ± 1.41
4.926GlyGly: 4.926 ± 2.82
2.463GlyHis: 2.463 ± 0.697
0.0GlyIle: 0.0 ± 0.0
2.463GlyLys: 2.463 ± 0.697
2.463GlyLeu: 2.463 ± 0.697
1.232GlyMet: 1.232 ± 1.263
7.389GlyAsn: 7.389 ± 2.68
4.926GlyPro: 4.926 ± 2.82
1.232GlyGln: 1.232 ± 1.904
7.389GlyArg: 7.389 ± 2.68
2.463GlySer: 2.463 ± 2.271
7.389GlyThr: 7.389 ± 3.27
3.695GlyVal: 3.695 ± 2.115
1.232GlyTrp: 1.232 ± 0.705
2.463GlyTyr: 2.463 ± 0.697
0.0GlyXaa: 0.0 ± 0.0
His
2.463HisAla: 2.463 ± 3.808
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
2.463HisPhe: 2.463 ± 0.697
1.232HisGly: 1.232 ± 0.705
1.232HisHis: 1.232 ± 0.705
2.463HisIle: 2.463 ± 1.565
1.232HisLys: 1.232 ± 0.705
1.232HisLeu: 1.232 ± 0.705
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.463HisPro: 2.463 ± 0.697
1.232HisGln: 1.232 ± 0.705
4.926HisArg: 4.926 ± 1.358
1.232HisSer: 1.232 ± 0.705
2.463HisThr: 2.463 ± 1.41
1.232HisVal: 1.232 ± 1.139
0.0HisTrp: 0.0 ± 0.0
2.463HisTyr: 2.463 ± 1.565
0.0HisXaa: 0.0 ± 0.0
Ile
2.463IleAla: 2.463 ± 2.271
0.0IleCys: 0.0 ± 0.0
3.695IleAsp: 3.695 ± 1.751
1.232IleGlu: 1.232 ± 0.705
1.232IlePhe: 1.232 ± 0.705
3.695IleGly: 3.695 ± 1.635
1.232IleHis: 1.232 ± 1.904
2.463IleIle: 2.463 ± 1.41
2.463IleLys: 2.463 ± 1.41
4.926IleLeu: 4.926 ± 1.088
1.232IleMet: 1.232 ± 0.705
3.695IleAsn: 3.695 ± 0.817
2.463IlePro: 2.463 ± 0.697
1.232IleGln: 1.232 ± 1.904
1.232IleArg: 1.232 ± 1.904
1.232IleSer: 1.232 ± 0.705
4.926IleThr: 4.926 ± 1.358
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
2.463IleTyr: 2.463 ± 3.808
0.0IleXaa: 0.0 ± 0.0
Lys
2.463LysAla: 2.463 ± 0.697
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.232LysGlu: 1.232 ± 1.904
0.0LysPhe: 0.0 ± 0.0
3.695LysGly: 3.695 ± 0.817
1.232LysHis: 1.232 ± 0.705
0.0LysIle: 0.0 ± 0.0
1.232LysLys: 1.232 ± 1.139
3.695LysLeu: 3.695 ± 1.506
0.0LysMet: 0.0 ± 0.0
1.232LysAsn: 1.232 ± 1.139
4.926LysPro: 4.926 ± 1.358
7.389LysGln: 7.389 ± 2.09
4.926LysArg: 4.926 ± 1.393
4.926LysSer: 4.926 ± 1.358
4.926LysThr: 4.926 ± 1.088
0.0LysVal: 0.0 ± 0.0
2.463LysTrp: 2.463 ± 0.697
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.926LeuAla: 4.926 ± 1.358
0.0LeuCys: 0.0 ± 0.0
4.926LeuAsp: 4.926 ± 5.302
2.463LeuGlu: 2.463 ± 2.271
6.158LeuPhe: 6.158 ± 2.004
7.389LeuGly: 7.389 ± 1.635
1.232LeuHis: 1.232 ± 1.139
6.158LeuIle: 6.158 ± 2.992
2.463LeuLys: 2.463 ± 1.565
3.695LeuLeu: 3.695 ± 2.115
0.0LeuMet: 0.0 ± 0.0
1.232LeuAsn: 1.232 ± 1.904
6.158LeuPro: 6.158 ± 2.99
3.695LeuGln: 3.695 ± 2.115
3.695LeuArg: 3.695 ± 1.751
9.852LeuSer: 9.852 ± 1.25
2.463LeuThr: 2.463 ± 1.565
1.232LeuVal: 1.232 ± 0.705
0.0LeuTrp: 0.0 ± 0.0
1.232LeuTyr: 1.232 ± 1.139
0.0LeuXaa: 0.0 ± 0.0
Met
2.463MetAla: 2.463 ± 1.41
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.463MetGlu: 2.463 ± 2.277
1.232MetPhe: 1.232 ± 0.705
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.463MetLeu: 2.463 ± 2.271
1.232MetMet: 1.232 ± 0.705
0.0MetAsn: 0.0 ± 0.0
2.463MetPro: 2.463 ± 1.41
1.232MetGln: 1.232 ± 1.139
1.232MetArg: 1.232 ± 0.705
1.232MetSer: 1.232 ± 0.705
1.232MetThr: 1.232 ± 0.705
1.232MetVal: 1.232 ± 0.705
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.695AsnAla: 3.695 ± 0.817
0.0AsnCys: 0.0 ± 0.0
1.232AsnAsp: 1.232 ± 0.705
1.232AsnGlu: 1.232 ± 0.705
2.463AsnPhe: 2.463 ± 1.41
2.463AsnGly: 2.463 ± 1.565
2.463AsnHis: 2.463 ± 1.41
3.695AsnIle: 3.695 ± 1.635
2.463AsnLys: 2.463 ± 0.697
4.926AsnLeu: 4.926 ± 1.358
1.232AsnMet: 1.232 ± 0.705
1.232AsnAsn: 1.232 ± 0.705
4.926AsnPro: 4.926 ± 2.82
2.463AsnGln: 2.463 ± 3.808
7.389AsnArg: 7.389 ± 4.696
0.0AsnSer: 0.0 ± 0.0
1.232AsnThr: 1.232 ± 1.139
3.695AsnVal: 3.695 ± 0.817
1.232AsnTrp: 1.232 ± 0.705
1.232AsnTyr: 1.232 ± 1.139
0.0AsnXaa: 0.0 ± 0.0
Pro
1.232ProAla: 1.232 ± 1.904
1.232ProCys: 1.232 ± 0.705
2.463ProAsp: 2.463 ± 1.565
3.695ProGlu: 3.695 ± 0.817
7.389ProPhe: 7.389 ± 2.606
3.695ProGly: 3.695 ± 2.115
0.0ProHis: 0.0 ± 0.0
2.463ProIle: 2.463 ± 1.41
3.695ProLys: 3.695 ± 0.817
4.926ProLeu: 4.926 ± 1.393
1.232ProMet: 1.232 ± 0.705
4.926ProAsn: 4.926 ± 1.755
9.852ProPro: 9.852 ± 4.061
3.695ProGln: 3.695 ± 2.115
2.463ProArg: 2.463 ± 1.41
4.926ProSer: 4.926 ± 1.358
13.547ProThr: 13.547 ± 3.476
1.232ProVal: 1.232 ± 0.705
3.695ProTrp: 3.695 ± 2.115
4.926ProTyr: 4.926 ± 2.82
0.0ProXaa: 0.0 ± 0.0
Gln
2.463GlnAla: 2.463 ± 0.697
0.0GlnCys: 0.0 ± 0.0
6.158GlnAsp: 6.158 ± 1.641
0.0GlnGlu: 0.0 ± 0.0
2.463GlnPhe: 2.463 ± 1.41
2.463GlnGly: 2.463 ± 1.41
2.463GlnHis: 2.463 ± 2.271
2.463GlnIle: 2.463 ± 0.697
2.463GlnLys: 2.463 ± 0.697
2.463GlnLeu: 2.463 ± 0.697
0.0GlnMet: 0.0 ± 0.0
7.389GlnAsn: 7.389 ± 0.942
1.232GlnPro: 1.232 ± 0.705
1.232GlnGln: 1.232 ± 1.904
6.158GlnArg: 6.158 ± 5.367
6.158GlnSer: 6.158 ± 0.829
3.695GlnThr: 3.695 ± 1.751
1.232GlnVal: 1.232 ± 0.705
2.463GlnTrp: 2.463 ± 1.565
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.158ArgAla: 6.158 ± 4.001
0.0ArgCys: 0.0 ± 0.0
1.232ArgAsp: 1.232 ± 0.705
2.463ArgGlu: 2.463 ± 2.277
1.232ArgPhe: 1.232 ± 0.705
7.389ArgGly: 7.389 ± 2.772
6.158ArgHis: 6.158 ± 3.525
2.463ArgIle: 2.463 ± 1.565
3.695ArgLys: 3.695 ± 3.047
7.389ArgLeu: 7.389 ± 4.896
0.0ArgMet: 0.0 ± 0.0
3.695ArgAsn: 3.695 ± 1.635
4.926ArgPro: 4.926 ± 2.82
1.232ArgGln: 1.232 ± 0.705
19.704ArgArg: 19.704 ± 2.586
6.158ArgSer: 6.158 ± 2.41
6.158ArgThr: 6.158 ± 1.641
4.926ArgVal: 4.926 ± 1.088
3.695ArgTrp: 3.695 ± 2.115
2.463ArgTyr: 2.463 ± 1.41
0.0ArgXaa: 0.0 ± 0.0
Ser
6.158SerAla: 6.158 ± 0.829
0.0SerCys: 0.0 ± 0.0
4.926SerAsp: 4.926 ± 1.393
2.463SerGlu: 2.463 ± 0.697
8.621SerPhe: 8.621 ± 2.128
2.463SerGly: 2.463 ± 0.697
2.463SerHis: 2.463 ± 2.271
4.926SerIle: 4.926 ± 1.088
4.926SerLys: 4.926 ± 1.088
3.695SerLeu: 3.695 ± 2.115
1.232SerMet: 1.232 ± 1.139
0.0SerAsn: 0.0 ± 0.0
3.695SerPro: 3.695 ± 0.817
2.463SerGln: 2.463 ± 1.565
6.158SerArg: 6.158 ± 2.004
3.695SerSer: 3.695 ± 0.817
6.158SerThr: 6.158 ± 3.302
3.695SerVal: 3.695 ± 0.817
2.463SerTrp: 2.463 ± 0.697
4.926SerTyr: 4.926 ± 1.393
0.0SerXaa: 0.0 ± 0.0
Thr
4.926ThrAla: 4.926 ± 1.755
2.463ThrCys: 2.463 ± 2.271
4.926ThrAsp: 4.926 ± 4.554
7.389ThrGlu: 7.389 ± 0.942
1.232ThrPhe: 1.232 ± 0.705
8.621ThrGly: 8.621 ± 2.128
0.0ThrHis: 0.0 ± 0.0
1.232ThrIle: 1.232 ± 0.705
1.232ThrLys: 1.232 ± 0.705
2.463ThrLeu: 2.463 ± 1.41
1.232ThrMet: 1.232 ± 0.705
3.695ThrAsn: 3.695 ± 1.506
9.852ThrPro: 9.852 ± 1.25
11.084ThrGln: 11.084 ± 3.768
2.463ThrArg: 2.463 ± 0.697
8.621ThrSer: 8.621 ± 0.279
8.621ThrThr: 8.621 ± 3.673
1.232ThrVal: 1.232 ± 0.705
1.232ThrTrp: 1.232 ± 0.705
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.695ValAla: 3.695 ± 0.817
0.0ValCys: 0.0 ± 0.0
1.232ValAsp: 1.232 ± 0.705
2.463ValGlu: 2.463 ± 0.697
1.232ValPhe: 1.232 ± 0.705
0.0ValGly: 0.0 ± 0.0
0.0ValHis: 0.0 ± 0.0
1.232ValIle: 1.232 ± 0.705
3.695ValLys: 3.695 ± 2.115
2.463ValLeu: 2.463 ± 1.565
1.232ValMet: 1.232 ± 0.705
0.0ValAsn: 0.0 ± 0.0
2.463ValPro: 2.463 ± 1.41
2.463ValGln: 2.463 ± 0.697
3.695ValArg: 3.695 ± 1.506
4.926ValSer: 4.926 ± 1.393
1.232ValThr: 1.232 ± 0.705
1.232ValVal: 1.232 ± 0.705
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.463TrpAla: 2.463 ± 1.41
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
2.463TrpGly: 2.463 ± 1.41
2.463TrpHis: 2.463 ± 1.41
0.0TrpIle: 0.0 ± 0.0
1.232TrpLys: 1.232 ± 0.705
2.463TrpLeu: 2.463 ± 0.697
1.232TrpMet: 1.232 ± 0.705
2.463TrpAsn: 2.463 ± 3.808
0.0TrpPro: 0.0 ± 0.0
2.463TrpGln: 2.463 ± 0.697
1.232TrpArg: 1.232 ± 0.705
2.463TrpSer: 2.463 ± 1.41
1.232TrpThr: 1.232 ± 0.705
0.0TrpVal: 0.0 ± 0.0
2.463TrpTrp: 2.463 ± 1.41
2.463TrpTyr: 2.463 ± 0.697
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
3.695TyrCys: 3.695 ± 1.751
1.232TyrAsp: 1.232 ± 0.705
0.0TyrGlu: 0.0 ± 0.0
1.232TyrPhe: 1.232 ± 0.705
1.232TyrGly: 1.232 ± 0.705
2.463TyrHis: 2.463 ± 1.41
2.463TyrIle: 2.463 ± 2.277
1.232TyrLys: 1.232 ± 0.705
1.232TyrLeu: 1.232 ± 1.904
2.463TyrMet: 2.463 ± 0.725
3.695TyrAsn: 3.695 ± 0.817
1.232TyrPro: 1.232 ± 0.705
2.463TyrGln: 2.463 ± 2.271
3.695TyrArg: 3.695 ± 1.635
1.232TyrSer: 1.232 ± 1.139
1.232TyrThr: 1.232 ± 0.705
1.232TyrVal: 1.232 ± 0.705
3.695TyrTrp: 3.695 ± 1.506
1.232TyrTyr: 1.232 ± 0.705
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (813 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski