Amino acid dipepetide frequency for Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	29.406AlaAla: 29.406 ± 0.361	1.494AlaCys: 1.494 ± 0.041	9.218AlaAsp: 9.218 ± 0.103	10.26AlaGlu: 10.26 ± 0.119	4.565AlaPhe: 4.565 ± 0.075	16.393AlaGly: 16.393 ± 0.171	2.136AlaHis: 2.136 ± 0.047	4.088AlaIle: 4.088 ± 0.06	2.596AlaLys: 2.596 ± 0.069	12.415AlaLeu: 12.415 ± 0.144	3.091AlaMet: 3.091 ± 0.054	2.122AlaAsn: 2.122 ± 0.048	6.817AlaPro: 6.817 ± 0.107	2.978AlaGln: 2.978 ± 0.049	9.383AlaArg: 9.383 ± 0.119	7.534AlaSer: 7.534 ± 0.1	6.873AlaThr: 6.873 ± 0.097	11.623AlaVal: 11.623 ± 0.13	2.575AlaTrp: 2.575 ± 0.057	2.422AlaTyr: 2.422 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.822CysAla: 0.822 ± 0.03	0.15CysCys: 0.15 ± 0.012	0.581CysAsp: 0.581 ± 0.028	0.479CysGlu: 0.479 ± 0.021	0.341CysPhe: 0.341 ± 0.018	1.11CysGly: 1.11 ± 0.037	0.278CysHis: 0.278 ± 0.017	0.263CysIle: 0.263 ± 0.015	0.139CysLys: 0.139 ± 0.011	0.882CysLeu: 0.882 ± 0.029	0.122CysMet: 0.122 ± 0.01	0.177CysAsn: 0.177 ± 0.013	0.612CysPro: 0.612 ± 0.024	0.178CysGln: 0.178 ± 0.013	0.826CysArg: 0.826 ± 0.029	0.437CysSer: 0.437 ± 0.021	0.447CysThr: 0.447 ± 0.019	0.784CysVal: 0.784 ± 0.03	0.148CysTrp: 0.148 ± 0.011	0.15CysTyr: 0.15 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	11.012AspAla: 11.012 ± 0.12	0.359AspCys: 0.359 ± 0.021	3.652AspAsp: 3.652 ± 0.066	3.588AspGlu: 3.588 ± 0.059	2.01AspPhe: 2.01 ± 0.047	6.324AspGly: 6.324 ± 0.102	1.413AspHis: 1.413 ± 0.037	1.085AspIle: 1.085 ± 0.04	0.908AspLys: 0.908 ± 0.034	6.225AspLeu: 6.225 ± 0.08	0.668AspMet: 0.668 ± 0.027	0.937AspAsn: 0.937 ± 0.03	5.382AspPro: 5.382 ± 0.088	1.216AspGln: 1.216 ± 0.033	5.613AspArg: 5.613 ± 0.065	1.745AspSer: 1.745 ± 0.042	2.515AspThr: 2.515 ± 0.048	3.978AspVal: 3.978 ± 0.068	0.853AspTrp: 0.853 ± 0.029	0.932AspTyr: 0.932 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	10.794GluAla: 10.794 ± 0.145	0.258GluCys: 0.258 ± 0.017	3.148GluAsp: 3.148 ± 0.058	3.64GluGlu: 3.64 ± 0.062	1.059GluPhe: 1.059 ± 0.032	4.613GluGly: 4.613 ± 0.055	1.494GluHis: 1.494 ± 0.044	1.92GluIle: 1.92 ± 0.043	1.727GluLys: 1.727 ± 0.054	6.18GluLeu: 6.18 ± 0.078	1.025GluMet: 1.025 ± 0.032	1.237GluAsn: 1.237 ± 0.035	4.415GluPro: 4.415 ± 0.069	1.923GluGln: 1.923 ± 0.045	5.934GluArg: 5.934 ± 0.074	2.309GluSer: 2.309 ± 0.041	2.768GluThr: 2.768 ± 0.05	4.682GluVal: 4.682 ± 0.072	0.417GluTrp: 0.417 ± 0.021	0.596GluTyr: 0.596 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.168PheAla: 4.168 ± 0.075	0.354PheCys: 0.354 ± 0.019	2.52PheAsp: 2.52 ± 0.047	2.18PheGlu: 2.18 ± 0.05	1.281PhePhe: 1.281 ± 0.044	3.344PheGly: 3.344 ± 0.059	0.776PheHis: 0.776 ± 0.027	0.842PheIle: 0.842 ± 0.029	0.672PheLys: 0.672 ± 0.027	3.171PheLeu: 3.171 ± 0.06	0.488PheMet: 0.488 ± 0.026	0.854PheAsn: 0.854 ± 0.03	1.574PhePro: 1.574 ± 0.037	0.79PheGln: 0.79 ± 0.032	2.355PheArg: 2.355 ± 0.046	1.677PheSer: 1.677 ± 0.044	1.893PheThr: 1.893 ± 0.041	2.484PheVal: 2.484 ± 0.047	0.463PheTrp: 0.463 ± 0.02	0.72PheTyr: 0.72 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.823GlyAla: 9.823 ± 0.111	1.08GlyCys: 1.08 ± 0.033	5.78GlyAsp: 5.78 ± 0.09	5.847GlyGlu: 5.847 ± 0.08	4.122GlyPhe: 4.122 ± 0.059	11.467GlyGly: 11.467 ± 0.171	2.147GlyHis: 2.147 ± 0.054	3.076GlyIle: 3.076 ± 0.055	2.268GlyLys: 2.268 ± 0.054	10.134GlyLeu: 10.134 ± 0.098	2.008GlyMet: 2.008 ± 0.044	1.973GlyAsn: 1.973 ± 0.052	5.615GlyPro: 5.615 ± 0.079	2.272GlyGln: 2.272 ± 0.052	8.589GlyArg: 8.589 ± 0.105	5.508GlySer: 5.508 ± 0.081	4.846GlyThr: 4.846 ± 0.079	8.654GlyVal: 8.654 ± 0.104	1.627GlyTrp: 1.627 ± 0.041	1.959GlyTyr: 1.959 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	3.384HisAla: 3.384 ± 0.066	0.225HisCys: 0.225 ± 0.014	1.251HisAsp: 1.251 ± 0.033	1.152HisGlu: 1.152 ± 0.037	0.715HisPhe: 0.715 ± 0.028	2.2HisGly: 2.2 ± 0.051	0.717HisHis: 0.717 ± 0.03	0.38HisIle: 0.38 ± 0.021	0.332HisLys: 0.332 ± 0.019	2.306HisLeu: 2.306 ± 0.051	0.255HisMet: 0.255 ± 0.014	0.429HisAsn: 0.429 ± 0.022	1.73HisPro: 1.73 ± 0.041	0.506HisGln: 0.506 ± 0.02	2.185HisArg: 2.185 ± 0.046	0.63HisSer: 0.63 ± 0.025	0.91HisThr: 0.91 ± 0.024	1.481HisVal: 1.481 ± 0.035	0.304HisTrp: 0.304 ± 0.014	0.372HisTyr: 0.372 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	4.292IleAla: 4.292 ± 0.062	0.275IleCys: 0.275 ± 0.017	2.714IleAsp: 2.714 ± 0.052	2.283IleGlu: 2.283 ± 0.058	0.847IlePhe: 0.847 ± 0.027	3.298IleGly: 3.298 ± 0.059	0.743IleHis: 0.743 ± 0.025	0.757IleIle: 0.757 ± 0.03	0.697IleLys: 0.697 ± 0.029	2.549IleLeu: 2.549 ± 0.053	0.314IleMet: 0.314 ± 0.018	0.769IleAsn: 0.769 ± 0.033	1.551IlePro: 1.551 ± 0.043	0.811IleGln: 0.811 ± 0.027	2.38IleArg: 2.38 ± 0.05	1.346IleSer: 1.346 ± 0.04	1.564IleThr: 1.564 ± 0.041	2.336IleVal: 2.336 ± 0.05	0.284IleTrp: 0.284 ± 0.017	0.538IleTyr: 0.538 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	2.359LysAla: 2.359 ± 0.057	0.151LysCys: 0.151 ± 0.012	0.938LysAsp: 0.938 ± 0.033	1.113LysGlu: 1.113 ± 0.038	0.477LysPhe: 0.477 ± 0.022	1.317LysGly: 1.317 ± 0.038	0.551LysHis: 0.551 ± 0.021	0.923LysIle: 0.923 ± 0.037	1.081LysLys: 1.081 ± 0.053	2.664LysLeu: 2.664 ± 0.059	0.453LysMet: 0.453 ± 0.023	0.495LysAsn: 0.495 ± 0.023	1.644LysPro: 1.644 ± 0.044	0.78LysGln: 0.78 ± 0.034	2.007LysArg: 2.007 ± 0.054	1.069LysSer: 1.069 ± 0.039	1.209LysThr: 1.209 ± 0.036	1.529LysVal: 1.529 ± 0.048	0.247LysTrp: 0.247 ± 0.017	0.365LysTyr: 0.365 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	15.99LeuAla: 15.99 ± 0.188	1.034LeuCys: 1.034 ± 0.034	6.728LeuAsp: 6.728 ± 0.084	5.758LeuGlu: 5.758 ± 0.082	3.076LeuPhe: 3.076 ± 0.058	9.924LeuGly: 9.924 ± 0.106	2.295LeuHis: 2.295 ± 0.057	3.194LeuIle: 3.194 ± 0.054	2.145LeuLys: 2.145 ± 0.051	12.029LeuLeu: 12.029 ± 0.155	1.615LeuMet: 1.615 ± 0.044	1.907LeuAsn: 1.907 ± 0.042	6.702LeuPro: 6.702 ± 0.096	2.599LeuGln: 2.599 ± 0.05	9.019LeuArg: 9.019 ± 0.105	5.066LeuSer: 5.066 ± 0.066	4.985LeuThr: 4.985 ± 0.073	7.701LeuVal: 7.701 ± 0.072	1.153LeuTrp: 1.153 ± 0.037	1.677LeuTyr: 1.677 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	2.176MetAla: 2.176 ± 0.046	0.134MetCys: 0.134 ± 0.012	0.875MetAsp: 0.875 ± 0.032	0.892MetGlu: 0.892 ± 0.03	0.469MetPhe: 0.469 ± 0.023	1.284MetGly: 1.284 ± 0.038	0.379MetHis: 0.379 ± 0.02	0.8MetIle: 0.8 ± 0.028	0.658MetLys: 0.658 ± 0.023	1.901MetLeu: 1.901 ± 0.044	0.369MetMet: 0.369 ± 0.02	0.572MetAsn: 0.572 ± 0.02	1.483MetPro: 1.483 ± 0.035	0.554MetGln: 0.554 ± 0.022	1.32MetArg: 1.32 ± 0.035	1.123MetSer: 1.123 ± 0.032	1.132MetThr: 1.132 ± 0.029	1.072MetVal: 1.072 ± 0.029	0.153MetTrp: 0.153 ± 0.012	0.26MetTyr: 0.26 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.728AsnAla: 2.728 ± 0.053	0.132AsnCys: 0.132 ± 0.01	1.132AsnAsp: 1.132 ± 0.036	0.912AsnGlu: 0.912 ± 0.031	0.663AsnPhe: 0.663 ± 0.028	1.798AsnGly: 1.798 ± 0.05	0.475AsnHis: 0.475 ± 0.018	0.576AsnIle: 0.576 ± 0.026	0.404AsnLys: 0.404 ± 0.021	2.268AsnLeu: 2.268 ± 0.049	0.264AsnMet: 0.264 ± 0.014	0.47AsnAsn: 0.47 ± 0.022	1.686AsnPro: 1.686 ± 0.034	0.61AsnGln: 0.61 ± 0.026	1.6AsnArg: 1.6 ± 0.041	0.67AsnSer: 0.67 ± 0.023	0.974AsnThr: 0.974 ± 0.029	1.376AsnVal: 1.376 ± 0.04	0.236AsnTrp: 0.236 ± 0.015	0.401AsnTyr: 0.401 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	11.177ProAla: 11.177 ± 0.155	0.382ProCys: 0.382 ± 0.019	4.044ProAsp: 4.044 ± 0.061	4.456ProGlu: 4.456 ± 0.07	1.726ProPhe: 1.726 ± 0.041	7.199ProGly: 7.199 ± 0.094	1.258ProHis: 1.258 ± 0.037	1.655ProIle: 1.655 ± 0.04	1.064ProLys: 1.064 ± 0.035	6.023ProLeu: 6.023 ± 0.093	1.059ProMet: 1.059 ± 0.032	1.012ProAsn: 1.012 ± 0.033	4.804ProPro: 4.804 ± 0.106	1.349ProGln: 1.349 ± 0.034	4.791ProArg: 4.791 ± 0.078	2.749ProSer: 2.749 ± 0.054	3.014ProThr: 3.014 ± 0.055	4.637ProVal: 4.637 ± 0.069	0.881ProTrp: 0.881 ± 0.028	0.87ProTyr: 0.87 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.364GlnAla: 3.364 ± 0.055	0.144GlnCys: 0.144 ± 0.012	1.2GlnAsp: 1.2 ± 0.041	1.388GlnGlu: 1.388 ± 0.039	0.596GlnPhe: 0.596 ± 0.024	1.532GlnGly: 1.532 ± 0.033	0.588GlnHis: 0.588 ± 0.022	0.898GlnIle: 0.898 ± 0.032	0.77GlnLys: 0.77 ± 0.028	2.535GlnLeu: 2.535 ± 0.047	0.473GlnMet: 0.473 ± 0.02	0.648GlnAsn: 0.648 ± 0.028	1.67GlnPro: 1.67 ± 0.042	0.913GlnGln: 0.913 ± 0.03	2.703GlnArg: 2.703 ± 0.055	1.078GlnSer: 1.078 ± 0.029	1.301GlnThr: 1.301 ± 0.032	1.77GlnVal: 1.77 ± 0.043	0.328GlnTrp: 0.328 ± 0.019	0.351GlnTyr: 0.351 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	9.117ArgAla: 9.117 ± 0.121	0.853ArgCys: 0.853 ± 0.03	4.374ArgAsp: 4.374 ± 0.069	4.922ArgGlu: 4.922 ± 0.08	3.379ArgPhe: 3.379 ± 0.052	7.404ArgGly: 7.404 ± 0.09	1.919ArgHis: 1.919 ± 0.041	2.931ArgIle: 2.931 ± 0.058	1.613ArgLys: 1.613 ± 0.048	9.841ArgLeu: 9.841 ± 0.117	1.717ArgMet: 1.717 ± 0.036	1.499ArgAsn: 1.499 ± 0.039	5.183ArgPro: 5.183 ± 0.078	1.958ArgGln: 1.958 ± 0.045	8.236ArgArg: 8.236 ± 0.136	4.266ArgSer: 4.266 ± 0.063	3.749ArgThr: 3.749 ± 0.066	7.061ArgVal: 7.061 ± 0.083	1.552ArgTrp: 1.552 ± 0.038	1.612ArgTyr: 1.612 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	6.209SerAla: 6.209 ± 0.079	0.372SerCys: 0.372 ± 0.018	2.616SerAsp: 2.616 ± 0.051	2.34SerGlu: 2.34 ± 0.045	1.853SerPhe: 1.853 ± 0.044	5.478SerGly: 5.478 ± 0.081	0.883SerHis: 0.883 ± 0.026	1.695SerIle: 1.695 ± 0.04	0.926SerLys: 0.926 ± 0.034	4.929SerLeu: 4.929 ± 0.079	0.996SerMet: 0.996 ± 0.031	1.0SerAsn: 1.0 ± 0.035	3.073SerPro: 3.073 ± 0.046	1.015SerGln: 1.015 ± 0.032	3.585SerArg: 3.585 ± 0.056	2.386SerSer: 2.386 ± 0.059	2.474SerThr: 2.474 ± 0.047	3.872SerVal: 3.872 ± 0.072	0.697SerTrp: 0.697 ± 0.025	0.801SerTyr: 0.801 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	6.406ThrAla: 6.406 ± 0.087	0.393ThrCys: 0.393 ± 0.021	2.823ThrAsp: 2.823 ± 0.058	2.221ThrGlu: 2.221 ± 0.044	1.606ThrPhe: 1.606 ± 0.04	5.112ThrGly: 5.112 ± 0.072	1.078ThrHis: 1.078 ± 0.031	1.682ThrIle: 1.682 ± 0.039	0.916ThrLys: 0.916 ± 0.037	6.373ThrLeu: 6.373 ± 0.089	0.762ThrMet: 0.762 ± 0.024	0.921ThrAsn: 0.921 ± 0.03	3.996ThrPro: 3.996 ± 0.065	1.103ThrGln: 1.103 ± 0.033	3.806ThrArg: 3.806 ± 0.069	2.182ThrSer: 2.182 ± 0.054	2.51ThrThr: 2.51 ± 0.054	3.65ThrVal: 3.65 ± 0.064	0.581ThrTrp: 0.581 ± 0.025	0.897ThrTyr: 0.897 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	10.768ValAla: 10.768 ± 0.103	0.784ValCys: 0.784 ± 0.03	4.936ValAsp: 4.936 ± 0.071	5.017ValGlu: 5.017 ± 0.082	2.625ValPhe: 2.625 ± 0.055	6.372ValGly: 6.372 ± 0.08	1.538ValHis: 1.538 ± 0.042	2.586ValIle: 2.586 ± 0.058	1.748ValLys: 1.748 ± 0.048	8.612ValLeu: 8.612 ± 0.105	1.383ValMet: 1.383 ± 0.036	1.592ValAsn: 1.592 ± 0.035	4.51ValPro: 4.51 ± 0.061	1.83ValGln: 1.83 ± 0.043	6.106ValArg: 6.106 ± 0.073	3.881ValSer: 3.881 ± 0.064	4.086ValThr: 4.086 ± 0.073	6.687ValVal: 6.687 ± 0.089	0.97ValTrp: 0.97 ± 0.034	1.477ValTyr: 1.477 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.513TrpAla: 1.513 ± 0.042	0.183TrpCys: 0.183 ± 0.013	0.681TrpAsp: 0.681 ± 0.025	0.688TrpGlu: 0.688 ± 0.025	0.575TrpPhe: 0.575 ± 0.025	0.96TrpGly: 0.96 ± 0.033	0.361TrpHis: 0.361 ± 0.018	0.603TrpIle: 0.603 ± 0.028	0.384TrpLys: 0.384 ± 0.019	1.683TrpLeu: 1.683 ± 0.043	0.305TrpMet: 0.305 ± 0.018	0.366TrpAsn: 0.366 ± 0.018	0.823TrpPro: 0.823 ± 0.031	0.365TrpGln: 0.365 ± 0.021	1.198TrpArg: 1.198 ± 0.033	0.963TrpSer: 0.963 ± 0.03	0.839TrpThr: 0.839 ± 0.031	0.944TrpVal: 0.944 ± 0.028	0.324TrpTrp: 0.324 ± 0.019	0.276TrpTyr: 0.276 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.484TyrAla: 2.484 ± 0.05	0.171TyrCys: 0.171 ± 0.012	1.202TyrAsp: 1.202 ± 0.035	1.001TyrGlu: 1.001 ± 0.033	0.623TyrPhe: 0.623 ± 0.024	1.668TyrGly: 1.668 ± 0.036	0.438TyrHis: 0.438 ± 0.019	0.393TyrIle: 0.393 ± 0.017	0.324TyrLys: 0.324 ± 0.017	1.878TyrLeu: 1.878 ± 0.042	0.236TyrMet: 0.236 ± 0.014	0.396TyrAsn: 0.396 ± 0.021	0.877TyrPro: 0.877 ± 0.03	0.501TyrGln: 0.501 ± 0.023	1.548TyrArg: 1.548 ± 0.036	0.582TyrSer: 0.582 ± 0.022	0.927TyrThr: 0.927 ± 0.027	1.184TyrVal: 1.184 ± 0.035	0.24TyrTrp: 0.24 ± 0.016	0.348TyrTyr: 0.348 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3269 proteins (1143530 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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