Amino acid dipepetide frequency for Avon-Heathcote Estuary associated circular virus 20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.976AlaAla: 11.976 ± 4.679
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
2.994AlaGlu: 2.994 ± 0.505
2.994AlaPhe: 2.994 ± 1.728
4.491AlaGly: 4.491 ± 2.592
0.0AlaHis: 0.0 ± 0.0
1.497AlaIle: 1.497 ± 1.368
2.994AlaLys: 2.994 ± 2.737
4.491AlaLeu: 4.491 ± 0.359
2.994AlaMet: 2.994 ± 2.737
0.0AlaAsn: 0.0 ± 0.0
4.491AlaPro: 4.491 ± 0.359
2.994AlaGln: 2.994 ± 0.505
7.485AlaArg: 7.485 ± 2.087
5.988AlaSer: 5.988 ± 1.223
4.491AlaThr: 4.491 ± 2.592
4.491AlaVal: 4.491 ± 2.592
1.497AlaTrp: 1.497 ± 0.864
7.485AlaTyr: 7.485 ± 0.145
0.0AlaXaa: 0.0 ± 0.0
Cys
1.497CysAla: 1.497 ± 0.864
0.0CysCys: 0.0 ± 0.0
1.497CysAsp: 1.497 ± 1.368
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
1.497CysHis: 1.497 ± 1.368
1.497CysIle: 1.497 ± 1.368
2.994CysLys: 2.994 ± 2.737
0.0CysLeu: 0.0 ± 0.0
2.994CysMet: 2.994 ± 0.505
0.0CysAsn: 0.0 ± 0.0
2.994CysPro: 2.994 ± 2.737
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.497CysTyr: 1.497 ± 1.368
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
2.994AspAsp: 2.994 ± 2.737
0.0AspGlu: 0.0 ± 0.0
2.994AspPhe: 2.994 ± 1.728
1.497AspGly: 1.497 ± 1.368
0.0AspHis: 0.0 ± 0.0
1.497AspIle: 1.497 ± 1.368
1.497AspLys: 1.497 ± 0.864
2.994AspLeu: 2.994 ± 2.737
0.0AspMet: 0.0 ± 0.0
2.994AspAsn: 2.994 ± 2.737
2.994AspPro: 2.994 ± 0.505
0.0AspGln: 0.0 ± 0.0
1.497AspArg: 1.497 ± 1.368
5.988AspSer: 5.988 ± 1.009
2.994AspThr: 2.994 ± 0.505
4.491AspVal: 4.491 ± 1.873
0.0AspTrp: 0.0 ± 0.0
1.497AspTyr: 1.497 ± 0.864
0.0AspXaa: 0.0 ± 0.0
Glu
7.485GluAla: 7.485 ± 2.087
2.994GluCys: 2.994 ± 2.737
1.497GluAsp: 1.497 ± 1.368
1.497GluGlu: 1.497 ± 1.368
2.994GluPhe: 2.994 ± 0.505
1.497GluGly: 1.497 ± 0.864
1.497GluHis: 1.497 ± 1.368
8.982GluIle: 8.982 ± 0.718
1.497GluLys: 1.497 ± 1.368
2.994GluLeu: 2.994 ± 0.505
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
2.994GluPro: 2.994 ± 2.737
0.0GluGln: 0.0 ± 0.0
2.994GluArg: 2.994 ± 0.505
1.497GluSer: 1.497 ± 0.864
1.497GluThr: 1.497 ± 1.368
4.491GluVal: 4.491 ± 2.592
0.0GluTrp: 0.0 ± 0.0
2.994GluTyr: 2.994 ± 0.505
0.0GluXaa: 0.0 ± 0.0
Phe
2.994PheAla: 2.994 ± 1.728
0.0PheCys: 0.0 ± 0.0
4.491PheAsp: 4.491 ± 1.873
1.497PheGlu: 1.497 ± 1.368
1.497PhePhe: 1.497 ± 0.864
2.994PheGly: 2.994 ± 1.728
1.497PheHis: 1.497 ± 1.368
1.497PheIle: 1.497 ± 0.864
7.485PheLys: 7.485 ± 0.145
1.497PheLeu: 1.497 ± 0.864
1.497PheMet: 1.497 ± 0.864
0.0PheAsn: 0.0 ± 0.0
1.497PhePro: 1.497 ± 0.864
1.497PheGln: 1.497 ± 1.368
0.0PheArg: 0.0 ± 0.0
1.497PheSer: 1.497 ± 0.864
1.497PheThr: 1.497 ± 0.864
2.994PheVal: 2.994 ± 1.728
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.988GlyAla: 5.988 ± 1.009
1.497GlyCys: 1.497 ± 1.368
4.491GlyAsp: 4.491 ± 0.359
4.491GlyGlu: 4.491 ± 0.359
0.0GlyPhe: 0.0 ± 0.0
4.491GlyGly: 4.491 ± 0.359
0.0GlyHis: 0.0 ± 0.0
5.988GlyIle: 5.988 ± 1.009
7.485GlyLys: 7.485 ± 0.145
1.497GlyLeu: 1.497 ± 0.864
1.497GlyMet: 1.497 ± 0.864
4.491GlyAsn: 4.491 ± 0.359
4.491GlyPro: 4.491 ± 2.592
5.988GlyGln: 5.988 ± 3.242
5.988GlyArg: 5.988 ± 1.223
7.485GlySer: 7.485 ± 4.319
7.485GlyThr: 7.485 ± 2.378
2.994GlyVal: 2.994 ± 1.728
2.994GlyTrp: 2.994 ± 1.728
4.491GlyTyr: 4.491 ± 1.873
0.0GlyXaa: 0.0 ± 0.0
His
2.994HisAla: 2.994 ± 1.728
1.497HisCys: 1.497 ± 0.864
0.0HisAsp: 0.0 ± 0.0
4.491HisGlu: 4.491 ± 4.105
1.497HisPhe: 1.497 ± 1.368
0.0HisGly: 0.0 ± 0.0
1.497HisHis: 1.497 ± 0.864
1.497HisIle: 1.497 ± 1.368
1.497HisLys: 1.497 ± 0.864
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.497HisAsn: 1.497 ± 0.864
1.497HisPro: 1.497 ± 1.368
0.0HisGln: 0.0 ± 0.0
1.497HisArg: 1.497 ± 0.864
0.0HisSer: 0.0 ± 0.0
1.497HisThr: 1.497 ± 0.864
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.497HisTyr: 1.497 ± 0.864
0.0HisXaa: 0.0 ± 0.0
Ile
1.497IleAla: 1.497 ± 1.368
0.0IleCys: 0.0 ± 0.0
1.497IleAsp: 1.497 ± 0.864
10.479IleGlu: 10.479 ± 2.882
0.0IlePhe: 0.0 ± 0.0
4.491IleGly: 4.491 ± 0.359
0.0IleHis: 0.0 ± 0.0
4.491IleIle: 4.491 ± 2.592
2.994IleLys: 2.994 ± 0.505
2.994IleLeu: 2.994 ± 0.505
0.0IleMet: 0.0 ± 0.0
1.497IleAsn: 1.497 ± 0.864
8.982IlePro: 8.982 ± 2.951
2.994IleGln: 2.994 ± 0.505
8.982IleArg: 8.982 ± 8.211
2.994IleSer: 2.994 ± 0.505
0.0IleThr: 0.0 ± 0.0
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
5.988IleTyr: 5.988 ± 3.242
0.0IleXaa: 0.0 ± 0.0
Lys
1.497LysAla: 1.497 ± 0.864
1.497LysCys: 1.497 ± 1.368
1.497LysAsp: 1.497 ± 1.368
1.497LysGlu: 1.497 ± 0.864
2.994LysPhe: 2.994 ± 1.728
8.982LysGly: 8.982 ± 0.718
2.994LysHis: 2.994 ± 0.505
2.994LysIle: 2.994 ± 0.505
8.982LysLys: 8.982 ± 0.718
1.497LysLeu: 1.497 ± 0.864
1.497LysMet: 1.497 ± 0.864
2.994LysAsn: 2.994 ± 0.505
0.0LysPro: 0.0 ± 0.0
2.994LysGln: 2.994 ± 0.505
4.491LysArg: 4.491 ± 0.359
5.988LysSer: 5.988 ± 1.009
1.497LysThr: 1.497 ± 0.864
4.491LysVal: 4.491 ± 2.592
1.497LysTrp: 1.497 ± 1.368
7.485LysTyr: 7.485 ± 2.087
0.0LysXaa: 0.0 ± 0.0
Leu
1.497LeuAla: 1.497 ± 0.864
1.497LeuCys: 1.497 ± 0.864
2.994LeuAsp: 2.994 ± 2.737
2.994LeuGlu: 2.994 ± 1.728
0.0LeuPhe: 0.0 ± 0.0
5.988LeuGly: 5.988 ± 1.223
0.0LeuHis: 0.0 ± 0.0
0.0LeuIle: 0.0 ± 0.0
1.497LeuLys: 1.497 ± 0.864
1.497LeuLeu: 1.497 ± 1.368
4.491LeuMet: 4.491 ± 1.172
2.994LeuAsn: 2.994 ± 2.737
2.994LeuPro: 2.994 ± 0.505
4.491LeuGln: 4.491 ± 0.359
7.485LeuArg: 7.485 ± 0.145
0.0LeuSer: 0.0 ± 0.0
1.497LeuThr: 1.497 ± 0.864
4.491LeuVal: 4.491 ± 2.592
1.497LeuTrp: 1.497 ± 0.864
2.994LeuTyr: 2.994 ± 0.505
0.0LeuXaa: 0.0 ± 0.0
Met
1.497MetAla: 1.497 ± 0.864
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.994MetGlu: 2.994 ± 0.505
1.497MetPhe: 1.497 ± 0.864
2.994MetGly: 2.994 ± 1.728
1.497MetHis: 1.497 ± 0.864
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
5.988MetLeu: 5.988 ± 1.009
5.988MetMet: 5.988 ± 1.009
1.497MetAsn: 1.497 ± 0.864
0.0MetPro: 0.0 ± 0.0
1.497MetGln: 1.497 ± 0.864
2.994MetArg: 2.994 ± 1.728
2.994MetSer: 2.994 ± 2.737
0.0MetThr: 0.0 ± 0.0
4.491MetVal: 4.491 ± 1.873
0.0MetTrp: 0.0 ± 0.0
2.994MetTyr: 2.994 ± 2.737
0.0MetXaa: 0.0 ± 0.0
Asn
2.994AsnAla: 2.994 ± 0.505
1.497AsnCys: 1.497 ± 1.368
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
2.994AsnPhe: 2.994 ± 1.728
5.988AsnGly: 5.988 ± 1.009
0.0AsnHis: 0.0 ± 0.0
4.491AsnIle: 4.491 ± 1.873
0.0AsnLys: 0.0 ± 0.0
2.994AsnLeu: 2.994 ± 0.505
4.491AsnMet: 4.491 ± 1.873
5.988AsnAsn: 5.988 ± 1.009
2.994AsnPro: 2.994 ± 1.728
0.0AsnGln: 0.0 ± 0.0
2.994AsnArg: 2.994 ± 1.728
4.491AsnSer: 4.491 ± 2.592
0.0AsnThr: 0.0 ± 0.0
1.497AsnVal: 1.497 ± 1.368
1.497AsnTrp: 1.497 ± 1.368
1.497AsnTyr: 1.497 ± 0.864
0.0AsnXaa: 0.0 ± 0.0
Pro
1.497ProAla: 1.497 ± 0.864
1.497ProCys: 1.497 ± 1.368
1.497ProAsp: 1.497 ± 1.368
7.485ProGlu: 7.485 ± 2.087
0.0ProPhe: 0.0 ± 0.0
1.497ProGly: 1.497 ± 0.864
1.497ProHis: 1.497 ± 0.864
2.994ProIle: 2.994 ± 1.728
0.0ProLys: 0.0 ± 0.0
0.0ProLeu: 0.0 ± 0.0
1.497ProMet: 1.497 ± 1.368
5.988ProAsn: 5.988 ± 1.009
7.485ProPro: 7.485 ± 0.145
0.0ProGln: 0.0 ± 0.0
8.982ProArg: 8.982 ± 0.718
4.491ProSer: 4.491 ± 0.359
4.491ProThr: 4.491 ± 2.592
7.485ProVal: 7.485 ± 2.087
0.0ProTrp: 0.0 ± 0.0
1.497ProTyr: 1.497 ± 0.864
0.0ProXaa: 0.0 ± 0.0
Gln
4.491GlnAla: 4.491 ± 0.359
0.0GlnCys: 0.0 ± 0.0
1.497GlnAsp: 1.497 ± 1.368
1.497GlnGlu: 1.497 ± 1.368
0.0GlnPhe: 0.0 ± 0.0
2.994GlnGly: 2.994 ± 2.737
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
5.988GlnLeu: 5.988 ± 1.009
2.994GlnMet: 2.994 ± 0.505
1.497GlnAsn: 1.497 ± 0.864
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
1.497GlnArg: 1.497 ± 0.864
1.497GlnSer: 1.497 ± 0.864
1.497GlnThr: 1.497 ± 1.368
1.497GlnVal: 1.497 ± 0.864
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
13.473ArgAla: 13.473 ± 1.078
0.0ArgCys: 0.0 ± 0.0
1.497ArgAsp: 1.497 ± 0.864
1.497ArgGlu: 1.497 ± 1.368
5.988ArgPhe: 5.988 ± 1.223
8.982ArgGly: 8.982 ± 0.718
4.491ArgHis: 4.491 ± 0.359
5.988ArgIle: 5.988 ± 1.009
8.982ArgLys: 8.982 ± 2.951
4.491ArgLeu: 4.491 ± 0.359
0.0ArgMet: 0.0 ± 0.0
4.491ArgAsn: 4.491 ± 0.359
1.497ArgPro: 1.497 ± 0.864
0.0ArgGln: 0.0 ± 0.0
5.988ArgArg: 5.988 ± 3.455
2.994ArgSer: 2.994 ± 2.737
2.994ArgThr: 2.994 ± 1.728
2.994ArgVal: 2.994 ± 0.505
0.0ArgTrp: 0.0 ± 0.0
8.982ArgTyr: 8.982 ± 3.746
0.0ArgXaa: 0.0 ± 0.0
Ser
5.988SerAla: 5.988 ± 1.009
1.497SerCys: 1.497 ± 1.368
4.491SerAsp: 4.491 ± 1.873
4.491SerGlu: 4.491 ± 0.359
1.497SerPhe: 1.497 ± 0.864
5.988SerGly: 5.988 ± 3.455
0.0SerHis: 0.0 ± 0.0
2.994SerIle: 2.994 ± 2.737
1.497SerLys: 1.497 ± 1.368
2.994SerLeu: 2.994 ± 1.728
2.994SerMet: 2.994 ± 1.728
2.994SerAsn: 2.994 ± 1.728
7.485SerPro: 7.485 ± 2.087
0.0SerGln: 0.0 ± 0.0
5.988SerArg: 5.988 ± 1.009
0.0SerSer: 0.0 ± 0.0
5.988SerThr: 5.988 ± 1.009
0.0SerVal: 0.0 ± 0.0
0.0SerTrp: 0.0 ± 0.0
2.994SerTyr: 2.994 ± 1.728
0.0SerXaa: 0.0 ± 0.0
Thr
2.994ThrAla: 2.994 ± 1.728
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
0.0ThrGlu: 0.0 ± 0.0
1.497ThrPhe: 1.497 ± 1.368
7.485ThrGly: 7.485 ± 2.378
2.994ThrHis: 2.994 ± 1.728
2.994ThrIle: 2.994 ± 0.505
2.994ThrLys: 2.994 ± 1.728
1.497ThrLeu: 1.497 ± 0.864
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
1.497ThrPro: 1.497 ± 0.864
2.994ThrGln: 2.994 ± 0.505
7.485ThrArg: 7.485 ± 0.145
4.491ThrSer: 4.491 ± 0.359
1.497ThrThr: 1.497 ± 0.864
4.491ThrVal: 4.491 ± 0.359
1.497ThrTrp: 1.497 ± 0.864
2.994ThrTyr: 2.994 ± 1.728
0.0ThrXaa: 0.0 ± 0.0
Val
1.497ValAla: 1.497 ± 1.368
0.0ValCys: 0.0 ± 0.0
2.994ValAsp: 2.994 ± 1.728
1.497ValGlu: 1.497 ± 0.864
4.491ValPhe: 4.491 ± 0.359
5.988ValGly: 5.988 ± 1.009
0.0ValHis: 0.0 ± 0.0
2.994ValIle: 2.994 ± 0.505
7.485ValLys: 7.485 ± 2.087
4.491ValLeu: 4.491 ± 2.592
1.497ValMet: 1.497 ± 1.407
1.497ValAsn: 1.497 ± 1.368
4.491ValPro: 4.491 ± 2.592
0.0ValGln: 0.0 ± 0.0
4.491ValArg: 4.491 ± 0.359
1.497ValSer: 1.497 ± 0.864
8.982ValThr: 8.982 ± 2.951
8.982ValVal: 8.982 ± 1.514
0.0ValTrp: 0.0 ± 0.0
1.497ValTyr: 1.497 ± 1.368
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.994TrpAsp: 2.994 ± 0.505
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.497TrpGly: 1.497 ± 0.864
0.0TrpHis: 0.0 ± 0.0
1.497TrpIle: 1.497 ± 1.368
1.497TrpLys: 1.497 ± 0.864
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.497TrpArg: 1.497 ± 0.864
1.497TrpSer: 1.497 ± 0.864
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.497TrpTrp: 1.497 ± 1.368
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.497TyrAla: 1.497 ± 1.368
2.994TyrCys: 2.994 ± 2.737
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
2.994TyrPhe: 2.994 ± 2.737
5.988TyrGly: 5.988 ± 3.242
2.994TyrHis: 2.994 ± 0.505
5.988TyrIle: 5.988 ± 1.009
5.988TyrLys: 5.988 ± 3.455
2.994TyrLeu: 2.994 ± 1.728
2.994TyrMet: 2.994 ± 0.505
5.988TyrAsn: 5.988 ± 1.223
1.497TyrPro: 1.497 ± 0.864
1.497TyrGln: 1.497 ± 0.864
2.994TyrArg: 2.994 ± 1.728
4.491TyrSer: 4.491 ± 1.873
1.497TyrThr: 1.497 ± 1.368
5.988TyrVal: 5.988 ± 1.009
0.0TyrTrp: 0.0 ± 0.0
2.994TyrTyr: 2.994 ± 2.737
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (669 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski