Amino acid dipepetide frequency for Agromyces binzhouensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.495AlaAla: 21.495 ± 0.189	0.654AlaCys: 0.654 ± 0.026	9.119AlaAsp: 9.119 ± 0.096	8.973AlaGlu: 8.973 ± 0.095	4.162AlaPhe: 4.162 ± 0.071	12.801AlaGly: 12.801 ± 0.124	2.531AlaHis: 2.531 ± 0.052	6.403AlaIle: 6.403 ± 0.077	2.561AlaLys: 2.561 ± 0.057	13.579AlaLeu: 13.579 ± 0.141	2.884AlaMet: 2.884 ± 0.056	2.408AlaAsn: 2.408 ± 0.049	6.544AlaPro: 6.544 ± 0.085	3.094AlaGln: 3.094 ± 0.057	9.876AlaArg: 9.876 ± 0.127	7.83AlaSer: 7.83 ± 0.103	7.362AlaThr: 7.362 ± 0.086	11.745AlaVal: 11.745 ± 0.132	2.031AlaTrp: 2.031 ± 0.046	2.494AlaTyr: 2.494 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.587CysAla: 0.587 ± 0.024	0.05CysCys: 0.05 ± 0.007	0.327CysAsp: 0.327 ± 0.019	0.247CysGlu: 0.247 ± 0.014	0.177CysPhe: 0.177 ± 0.011	0.519CysGly: 0.519 ± 0.026	0.127CysHis: 0.127 ± 0.011	0.172CysIle: 0.172 ± 0.013	0.05CysLys: 0.05 ± 0.006	0.364CysLeu: 0.364 ± 0.017	0.063CysMet: 0.063 ± 0.008	0.087CysAsn: 0.087 ± 0.009	0.294CysPro: 0.294 ± 0.018	0.103CysGln: 0.103 ± 0.01	0.359CysArg: 0.359 ± 0.02	0.309CysSer: 0.309 ± 0.018	0.31CysThr: 0.31 ± 0.021	0.399CysVal: 0.399 ± 0.019	0.071CysTrp: 0.071 ± 0.009	0.092CysTyr: 0.092 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	10.024AspAla: 10.024 ± 0.115	0.258AspCys: 0.258 ± 0.018	4.776AspAsp: 4.776 ± 0.075	5.045AspGlu: 5.045 ± 0.081	1.72AspPhe: 1.72 ± 0.047	6.745AspGly: 6.745 ± 0.088	1.331AspHis: 1.331 ± 0.038	2.021AspIle: 2.021 ± 0.044	0.717AspLys: 0.717 ± 0.032	6.846AspLeu: 6.846 ± 0.092	0.767AspMet: 0.767 ± 0.028	0.777AspAsn: 0.777 ± 0.034	4.498AspPro: 4.498 ± 0.06	1.38AspGln: 1.38 ± 0.04	5.34AspArg: 5.34 ± 0.089	2.348AspSer: 2.348 ± 0.05	2.555AspThr: 2.555 ± 0.051	5.769AspVal: 5.769 ± 0.077	1.098AspTrp: 1.098 ± 0.033	1.262AspTyr: 1.262 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	7.955GluAla: 7.955 ± 0.101	0.27GluCys: 0.27 ± 0.017	2.673GluAsp: 2.673 ± 0.056	3.341GluGlu: 3.341 ± 0.057	2.043GluPhe: 2.043 ± 0.05	4.391GluGly: 4.391 ± 0.069	1.734GluHis: 1.734 ± 0.042	2.652GluIle: 2.652 ± 0.054	1.078GluLys: 1.078 ± 0.045	7.356GluLeu: 7.356 ± 0.083	0.878GluMet: 0.878 ± 0.026	1.049GluAsn: 1.049 ± 0.032	3.558GluPro: 3.558 ± 0.061	2.189GluGln: 2.189 ± 0.05	6.189GluArg: 6.189 ± 0.084	2.937GluSer: 2.937 ± 0.05	3.032GluThr: 3.032 ± 0.057	5.365GluVal: 5.365 ± 0.084	1.007GluTrp: 1.007 ± 0.031	1.228GluTyr: 1.228 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.449PheAla: 4.449 ± 0.061	0.161PheCys: 0.161 ± 0.013	2.608PheAsp: 2.608 ± 0.052	1.959PheGlu: 1.959 ± 0.049	0.987PhePhe: 0.987 ± 0.038	3.463PheGly: 3.463 ± 0.065	0.598PheHis: 0.598 ± 0.023	1.208PheIle: 1.208 ± 0.036	0.383PheLys: 0.383 ± 0.022	2.81PheLeu: 2.81 ± 0.053	0.448PheMet: 0.448 ± 0.021	0.579PheAsn: 0.579 ± 0.024	1.406PhePro: 1.406 ± 0.036	0.715PheGln: 0.715 ± 0.028	2.004PheArg: 2.004 ± 0.051	1.608PheSer: 1.608 ± 0.041	1.993PheThr: 1.993 ± 0.047	2.824PheVal: 2.824 ± 0.057	0.539PheTrp: 0.539 ± 0.024	0.616PheTyr: 0.616 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	11.417GlyAla: 11.417 ± 0.13	0.568GlyCys: 0.568 ± 0.021	5.688GlyAsp: 5.688 ± 0.085	5.467GlyGlu: 5.467 ± 0.075	3.346GlyPhe: 3.346 ± 0.06	8.159GlyGly: 8.159 ± 0.112	1.785GlyHis: 1.785 ± 0.042	4.852GlyIle: 4.852 ± 0.069	1.761GlyLys: 1.761 ± 0.044	8.998GlyLeu: 8.998 ± 0.11	2.022GlyMet: 2.022 ± 0.043	1.604GlyAsn: 1.604 ± 0.046	4.125GlyPro: 4.125 ± 0.064	2.085GlyGln: 2.085 ± 0.055	7.249GlyArg: 7.249 ± 0.091	5.218GlySer: 5.218 ± 0.065	5.406GlyThr: 5.406 ± 0.09	8.297GlyVal: 8.297 ± 0.085	1.766GlyTrp: 1.766 ± 0.043	2.216GlyTyr: 2.216 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.575HisAla: 2.575 ± 0.052	0.11HisCys: 0.11 ± 0.01	1.487HisAsp: 1.487 ± 0.039	1.282HisGlu: 1.282 ± 0.04	0.572HisPhe: 0.572 ± 0.023	2.167HisGly: 2.167 ± 0.053	0.567HisHis: 0.567 ± 0.027	0.593HisIle: 0.593 ± 0.024	0.25HisLys: 0.25 ± 0.014	2.062HisLeu: 2.062 ± 0.055	0.285HisMet: 0.285 ± 0.017	0.313HisAsn: 0.313 ± 0.017	1.589HisPro: 1.589 ± 0.046	0.412HisGln: 0.412 ± 0.019	1.776HisArg: 1.776 ± 0.045	0.9HisSer: 0.9 ± 0.026	0.843HisThr: 0.843 ± 0.028	1.836HisVal: 1.836 ± 0.047	0.283HisTrp: 0.283 ± 0.016	0.435HisTyr: 0.435 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	7.131IleAla: 7.131 ± 0.096	0.21IleCys: 0.21 ± 0.015	3.411IleAsp: 3.411 ± 0.069	2.988IleGlu: 2.988 ± 0.057	1.059IlePhe: 1.059 ± 0.039	4.646IleGly: 4.646 ± 0.076	0.662IleHis: 0.662 ± 0.025	1.565IleIle: 1.565 ± 0.047	0.614IleLys: 0.614 ± 0.022	3.425IleLeu: 3.425 ± 0.061	0.573IleMet: 0.573 ± 0.025	0.675IleAsn: 0.675 ± 0.025	2.32IlePro: 2.32 ± 0.055	0.831IleGln: 0.831 ± 0.032	2.993IleArg: 2.993 ± 0.053	1.917IleSer: 1.917 ± 0.044	2.499IleThr: 2.499 ± 0.054	4.604IleVal: 4.604 ± 0.077	0.524IleTrp: 0.524 ± 0.024	0.656IleTyr: 0.656 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	2.039LysAla: 2.039 ± 0.047	0.06LysCys: 0.06 ± 0.008	0.851LysAsp: 0.851 ± 0.031	0.81LysGlu: 0.81 ± 0.034	0.448LysPhe: 0.448 ± 0.02	1.407LysGly: 1.407 ± 0.04	0.394LysHis: 0.394 ± 0.02	0.682LysIle: 0.682 ± 0.027	0.523LysLys: 0.523 ± 0.028	1.759LysLeu: 1.759 ± 0.043	0.291LysMet: 0.291 ± 0.016	0.382LysAsn: 0.382 ± 0.02	1.035LysPro: 1.035 ± 0.034	0.595LysGln: 0.595 ± 0.027	1.441LysArg: 1.441 ± 0.037	0.937LysSer: 0.937 ± 0.03	1.009LysThr: 1.009 ± 0.033	1.514LysVal: 1.514 ± 0.045	0.245LysTrp: 0.245 ± 0.016	0.403LysTyr: 0.403 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	15.326LeuAla: 15.326 ± 0.151	0.401LeuCys: 0.401 ± 0.018	7.17LeuAsp: 7.17 ± 0.081	6.03LeuGlu: 6.03 ± 0.079	2.726LeuPhe: 2.726 ± 0.054	9.676LeuGly: 9.676 ± 0.108	1.862LeuHis: 1.862 ± 0.048	3.999LeuIle: 3.999 ± 0.067	1.567LeuLys: 1.567 ± 0.041	9.536LeuLeu: 9.536 ± 0.12	1.524LeuMet: 1.524 ± 0.038	1.624LeuAsn: 1.624 ± 0.039	5.376LeuPro: 5.376 ± 0.077	2.254LeuGln: 2.254 ± 0.046	7.272LeuArg: 7.272 ± 0.108	5.028LeuSer: 5.028 ± 0.078	5.323LeuThr: 5.323 ± 0.071	10.13LeuVal: 10.13 ± 0.118	1.143LeuTrp: 1.143 ± 0.037	1.577LeuTyr: 1.577 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.121MetAla: 2.121 ± 0.042	0.084MetCys: 0.084 ± 0.01	0.803MetAsp: 0.803 ± 0.028	0.654MetGlu: 0.654 ± 0.028	0.546MetPhe: 0.546 ± 0.023	1.266MetGly: 1.266 ± 0.035	0.388MetHis: 0.388 ± 0.02	0.773MetIle: 0.773 ± 0.027	0.333MetLys: 0.333 ± 0.018	1.91MetLeu: 1.91 ± 0.043	0.296MetMet: 0.296 ± 0.022	0.441MetAsn: 0.441 ± 0.02	1.221MetPro: 1.221 ± 0.031	0.518MetGln: 0.518 ± 0.023	1.514MetArg: 1.514 ± 0.039	1.332MetSer: 1.332 ± 0.037	1.511MetThr: 1.511 ± 0.04	1.328MetVal: 1.328 ± 0.034	0.189MetTrp: 0.189 ± 0.012	0.266MetTyr: 0.266 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.308AsnAla: 2.308 ± 0.049	0.113AsnCys: 0.113 ± 0.01	1.039AsnAsp: 1.039 ± 0.036	0.952AsnGlu: 0.952 ± 0.031	0.596AsnPhe: 0.596 ± 0.026	1.781AsnGly: 1.781 ± 0.045	0.384AsnHis: 0.384 ± 0.02	0.692AsnIle: 0.692 ± 0.031	0.279AsnLys: 0.279 ± 0.017	1.764AsnLeu: 1.764 ± 0.043	0.28AsnMet: 0.28 ± 0.019	0.364AsnAsn: 0.364 ± 0.021	1.48AsnPro: 1.48 ± 0.04	0.472AsnGln: 0.472 ± 0.022	1.321AsnArg: 1.321 ± 0.042	0.888AsnSer: 0.888 ± 0.032	1.018AsnThr: 1.018 ± 0.031	1.584AsnVal: 1.584 ± 0.036	0.276AsnTrp: 0.276 ± 0.016	0.409AsnTyr: 0.409 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	7.33ProAla: 7.33 ± 0.089	0.181ProCys: 0.181 ± 0.013	4.285ProAsp: 4.285 ± 0.062	4.196ProGlu: 4.196 ± 0.065	1.704ProPhe: 1.704 ± 0.038	5.214ProGly: 5.214 ± 0.083	1.089ProHis: 1.089 ± 0.033	2.244ProIle: 2.244 ± 0.046	1.01ProLys: 1.01 ± 0.033	4.632ProLeu: 4.632 ± 0.066	0.943ProMet: 0.943 ± 0.024	1.086ProAsn: 1.086 ± 0.029	2.457ProPro: 2.457 ± 0.054	1.245ProGln: 1.245 ± 0.035	3.429ProArg: 3.429 ± 0.061	3.171ProSer: 3.171 ± 0.06	3.257ProThr: 3.257 ± 0.06	5.109ProVal: 5.109 ± 0.076	0.892ProTrp: 0.892 ± 0.029	1.054ProTyr: 1.054 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.224GlnAla: 3.224 ± 0.059	0.087GlnCys: 0.087 ± 0.009	1.023GlnAsp: 1.023 ± 0.031	1.144GlnGlu: 1.144 ± 0.042	0.755GlnPhe: 0.755 ± 0.025	1.875GlnGly: 1.875 ± 0.048	0.57GlnHis: 0.57 ± 0.021	1.009GlnIle: 1.009 ± 0.032	0.52GlnLys: 0.52 ± 0.025	2.734GlnLeu: 2.734 ± 0.06	0.402GlnMet: 0.402 ± 0.023	0.5GlnAsn: 0.5 ± 0.025	1.345GlnPro: 1.345 ± 0.035	0.983GlnGln: 0.983 ± 0.036	2.185GlnArg: 2.185 ± 0.055	1.246GlnSer: 1.246 ± 0.038	1.211GlnThr: 1.211 ± 0.037	2.337GlnVal: 2.337 ± 0.042	0.395GlnTrp: 0.395 ± 0.02	0.564GlnTyr: 0.564 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	9.712ArgAla: 9.712 ± 0.123	0.323ArgCys: 0.323 ± 0.018	4.766ArgAsp: 4.766 ± 0.077	4.669ArgGlu: 4.669 ± 0.079	2.624ArgPhe: 2.624 ± 0.05	5.918ArgGly: 5.918 ± 0.088	1.762ArgHis: 1.762 ± 0.044	3.888ArgIle: 3.888 ± 0.065	1.203ArgLys: 1.203 ± 0.037	7.928ArgLeu: 7.928 ± 0.121	1.855ArgMet: 1.855 ± 0.04	1.432ArgAsn: 1.432 ± 0.035	4.062ArgPro: 4.062 ± 0.074	1.813ArgGln: 1.813 ± 0.046	7.48ArgArg: 7.48 ± 0.116	4.276ArgSer: 4.276 ± 0.072	4.422ArgThr: 4.422 ± 0.055	6.591ArgVal: 6.591 ± 0.089	1.252ArgTrp: 1.252 ± 0.039	1.696ArgTyr: 1.696 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.782SerAla: 6.782 ± 0.082	0.246SerCys: 0.246 ± 0.016	3.028SerAsp: 3.028 ± 0.062	2.739SerGlu: 2.739 ± 0.053	1.765SerPhe: 1.765 ± 0.043	5.704SerGly: 5.704 ± 0.074	0.931SerHis: 0.931 ± 0.03	2.433SerIle: 2.433 ± 0.054	0.961SerLys: 0.961 ± 0.032	4.958SerLeu: 4.958 ± 0.08	1.053SerMet: 1.053 ± 0.033	1.015SerAsn: 1.015 ± 0.034	2.964SerPro: 2.964 ± 0.057	1.198SerGln: 1.198 ± 0.036	3.808SerArg: 3.808 ± 0.065	2.953SerSer: 2.953 ± 0.06	3.375SerThr: 3.375 ± 0.056	4.632SerVal: 4.632 ± 0.071	0.839SerTrp: 0.839 ± 0.031	1.087SerTyr: 1.087 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	7.125ThrAla: 7.125 ± 0.093	0.269ThrCys: 0.269 ± 0.015	3.544ThrAsp: 3.544 ± 0.055	2.902ThrGlu: 2.902 ± 0.05	1.808ThrPhe: 1.808 ± 0.045	5.691ThrGly: 5.691 ± 0.086	1.088ThrHis: 1.088 ± 0.031	2.624ThrIle: 2.624 ± 0.051	0.995ThrLys: 0.995 ± 0.035	5.298ThrLeu: 5.298 ± 0.063	0.922ThrMet: 0.922 ± 0.029	1.047ThrAsn: 1.047 ± 0.033	3.618ThrPro: 3.618 ± 0.051	1.203ThrGln: 1.203 ± 0.039	3.726ThrArg: 3.726 ± 0.067	3.079ThrSer: 3.079 ± 0.056	3.59ThrThr: 3.59 ± 0.071	5.453ThrVal: 5.453 ± 0.076	0.875ThrTrp: 0.875 ± 0.029	1.089ThrTyr: 1.089 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	12.688ValAla: 12.688 ± 0.129	0.442ValCys: 0.442 ± 0.024	6.455ValAsp: 6.455 ± 0.08	5.663ValGlu: 5.663 ± 0.067	2.995ValPhe: 2.995 ± 0.058	7.573ValGly: 7.573 ± 0.092	1.87ValHis: 1.87 ± 0.048	4.214ValIle: 4.214 ± 0.064	1.465ValLys: 1.465 ± 0.041	9.624ValLeu: 9.624 ± 0.128	1.416ValMet: 1.416 ± 0.039	1.823ValAsn: 1.823 ± 0.04	4.965ValPro: 4.965 ± 0.071	1.999ValGln: 1.999 ± 0.048	6.656ValArg: 6.656 ± 0.097	4.572ValSer: 4.572 ± 0.065	5.244ValThr: 5.244 ± 0.074	9.807ValVal: 9.807 ± 0.123	1.127ValTrp: 1.127 ± 0.031	1.559ValTyr: 1.559 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.782TrpAla: 1.782 ± 0.045	0.095TrpCys: 0.095 ± 0.009	0.798TrpAsp: 0.798 ± 0.031	0.708TrpGlu: 0.708 ± 0.028	0.608TrpPhe: 0.608 ± 0.023	1.092TrpGly: 1.092 ± 0.035	0.336TrpHis: 0.336 ± 0.02	0.718TrpIle: 0.718 ± 0.028	0.285TrpLys: 0.285 ± 0.017	1.752TrpLeu: 1.752 ± 0.046	0.365TrpMet: 0.365 ± 0.02	0.404TrpAsn: 0.404 ± 0.022	0.737TrpPro: 0.737 ± 0.028	0.518TrpGln: 0.518 ± 0.019	1.321TrpArg: 1.321 ± 0.034	0.942TrpSer: 0.942 ± 0.032	0.905TrpThr: 0.905 ± 0.031	1.188TrpVal: 1.188 ± 0.036	0.405TrpTrp: 0.405 ± 0.023	0.323TrpTyr: 0.323 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.476TyrAla: 2.476 ± 0.05	0.122TyrCys: 0.122 ± 0.011	1.426TyrAsp: 1.426 ± 0.038	1.157TyrGlu: 1.157 ± 0.039	0.716TyrPhe: 0.716 ± 0.025	1.941TyrGly: 1.941 ± 0.046	0.33TyrHis: 0.33 ± 0.02	0.561TyrIle: 0.561 ± 0.026	0.269TyrLys: 0.269 ± 0.017	2.207TyrLeu: 2.207 ± 0.05	0.226TyrMet: 0.226 ± 0.015	0.391TyrAsn: 0.391 ± 0.02	0.937TyrPro: 0.937 ± 0.037	0.501TyrGln: 0.501 ± 0.022	1.734TyrArg: 1.734 ± 0.039	0.981TyrSer: 0.981 ± 0.033	1.08TyrThr: 1.08 ± 0.032	1.647TyrVal: 1.647 ± 0.037	0.324TyrTrp: 0.324 ± 0.017	0.465TyrTyr: 0.465 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3584 proteins (1048746 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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