Amino acid dipepetide frequency for Camelimonas lactis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.382AlaAla: 21.382 ± 0.234	1.188AlaCys: 1.188 ± 0.033	7.543AlaAsp: 7.543 ± 0.088	6.997AlaGlu: 6.997 ± 0.094	4.683AlaPhe: 4.683 ± 0.073	13.611AlaGly: 13.611 ± 0.151	2.504AlaHis: 2.504 ± 0.05	6.633AlaIle: 6.633 ± 0.074	3.302AlaLys: 3.302 ± 0.07	14.369AlaLeu: 14.369 ± 0.14	3.939AlaMet: 3.939 ± 0.068	2.982AlaAsn: 2.982 ± 0.057	8.118AlaPro: 8.118 ± 0.131	4.208AlaGln: 4.208 ± 0.069	11.564AlaArg: 11.564 ± 0.124	7.516AlaSer: 7.516 ± 0.082	6.642AlaThr: 6.642 ± 0.097	9.449AlaVal: 9.449 ± 0.097	1.981AlaTrp: 1.981 ± 0.046	2.34AlaTyr: 2.34 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.125CysAla: 1.125 ± 0.032	0.11CysCys: 0.11 ± 0.01	0.507CysAsp: 0.507 ± 0.021	0.354CysGlu: 0.354 ± 0.018	0.318CysPhe: 0.318 ± 0.016	0.899CysGly: 0.899 ± 0.031	0.182CysHis: 0.182 ± 0.014	0.391CysIle: 0.391 ± 0.017	0.166CysLys: 0.166 ± 0.011	0.741CysLeu: 0.741 ± 0.025	0.178CysMet: 0.178 ± 0.012	0.201CysAsn: 0.201 ± 0.012	0.455CysPro: 0.455 ± 0.023	0.219CysGln: 0.219 ± 0.014	0.602CysArg: 0.602 ± 0.023	0.401CysSer: 0.401 ± 0.019	0.334CysThr: 0.334 ± 0.015	0.631CysVal: 0.631 ± 0.021	0.113CysTrp: 0.113 ± 0.009	0.179CysTyr: 0.179 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.13AspAla: 8.13 ± 0.084	0.397AspCys: 0.397 ± 0.02	3.407AspAsp: 3.407 ± 0.072	3.069AspGlu: 3.069 ± 0.056	2.001AspPhe: 2.001 ± 0.043	5.533AspGly: 5.533 ± 0.077	1.217AspHis: 1.217 ± 0.038	2.921AspIle: 2.921 ± 0.05	1.34AspLys: 1.34 ± 0.038	5.597AspLeu: 5.597 ± 0.073	1.503AspMet: 1.503 ± 0.031	1.501AspAsn: 1.501 ± 0.042	3.432AspPro: 3.432 ± 0.057	1.631AspGln: 1.631 ± 0.045	4.377AspArg: 4.377 ± 0.067	2.203AspSer: 2.203 ± 0.039	2.075AspThr: 2.075 ± 0.044	4.349AspVal: 4.349 ± 0.068	0.873AspTrp: 0.873 ± 0.025	1.354AspTyr: 1.354 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.706GluAla: 7.706 ± 0.098	0.317GluCys: 0.317 ± 0.017	2.35GluAsp: 2.35 ± 0.044	2.615GluGlu: 2.615 ± 0.066	1.517GluPhe: 1.517 ± 0.028	3.88GluGly: 3.88 ± 0.059	1.037GluHis: 1.037 ± 0.032	2.794GluIle: 2.794 ± 0.05	1.966GluLys: 1.966 ± 0.052	5.002GluLeu: 5.002 ± 0.073	1.245GluMet: 1.245 ± 0.035	1.361GluAsn: 1.361 ± 0.041	2.593GluPro: 2.593 ± 0.044	2.063GluGln: 2.063 ± 0.044	4.729GluArg: 4.729 ± 0.077	1.857GluSer: 1.857 ± 0.036	3.175GluThr: 3.175 ± 0.051	3.332GluVal: 3.332 ± 0.054	0.617GluTrp: 0.617 ± 0.025	0.868GluTyr: 0.868 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	4.514PheAla: 4.514 ± 0.074	0.371PheCys: 0.371 ± 0.018	2.342PheAsp: 2.342 ± 0.046	1.657PheGlu: 1.657 ± 0.035	1.236PhePhe: 1.236 ± 0.041	3.73PheGly: 3.73 ± 0.07	0.716PheHis: 0.716 ± 0.024	1.718PheIle: 1.718 ± 0.044	0.7PheLys: 0.7 ± 0.029	3.096PheLeu: 3.096 ± 0.051	0.851PheMet: 0.851 ± 0.028	1.024PheAsn: 1.024 ± 0.032	1.619PhePro: 1.619 ± 0.037	0.976PheGln: 0.976 ± 0.03	2.523PheArg: 2.523 ± 0.051	2.195PheSer: 2.195 ± 0.04	1.99PheThr: 1.99 ± 0.044	2.51PheVal: 2.51 ± 0.055	0.492PheTrp: 0.492 ± 0.022	0.839PheTyr: 0.839 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	12.727GlyAla: 12.727 ± 0.151	0.782GlyCys: 0.782 ± 0.027	5.141GlyAsp: 5.141 ± 0.083	4.852GlyGlu: 4.852 ± 0.073	3.556GlyPhe: 3.556 ± 0.057	8.566GlyGly: 8.566 ± 0.164	1.893GlyHis: 1.893 ± 0.045	3.149GlyIle: 3.149 ± 0.061	3.35GlyLys: 3.35 ± 0.059	9.029GlyLeu: 9.029 ± 0.094	2.394GlyMet: 2.394 ± 0.052	2.03GlyAsn: 2.03 ± 0.063	4.18GlyPro: 4.18 ± 0.06	3.332GlyGln: 3.332 ± 0.059	6.892GlyArg: 6.892 ± 0.086	4.431GlySer: 4.431 ± 0.081	3.084GlyThr: 3.084 ± 0.061	8.174GlyVal: 8.174 ± 0.095	1.468GlyTrp: 1.468 ± 0.043	2.256GlyTyr: 2.256 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.587HisAla: 2.587 ± 0.051	0.221HisCys: 0.221 ± 0.015	1.249HisAsp: 1.249 ± 0.042	0.958HisGlu: 0.958 ± 0.03	0.715HisPhe: 0.715 ± 0.024	2.126HisGly: 2.126 ± 0.044	0.493HisHis: 0.493 ± 0.019	0.904HisIle: 0.904 ± 0.03	0.389HisLys: 0.389 ± 0.021	1.769HisLeu: 1.769 ± 0.039	0.516HisMet: 0.516 ± 0.024	0.449HisAsn: 0.449 ± 0.024	1.331HisPro: 1.331 ± 0.04	0.518HisGln: 0.518 ± 0.021	1.27HisArg: 1.27 ± 0.035	0.735HisSer: 0.735 ± 0.026	0.748HisThr: 0.748 ± 0.028	1.61HisVal: 1.61 ± 0.036	0.29HisTrp: 0.29 ± 0.016	0.508HisTyr: 0.508 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	7.048IleAla: 7.048 ± 0.089	0.494IleCys: 0.494 ± 0.021	3.263IleAsp: 3.263 ± 0.055	2.594IleGlu: 2.594 ± 0.054	1.426IlePhe: 1.426 ± 0.038	4.572IleGly: 4.572 ± 0.073	0.83IleHis: 0.83 ± 0.031	2.206IleIle: 2.206 ± 0.047	1.044IleLys: 1.044 ± 0.034	3.691IleLeu: 3.691 ± 0.059	0.912IleMet: 0.912 ± 0.031	1.448IleAsn: 1.448 ± 0.041	2.125IlePro: 2.125 ± 0.049	1.15IleGln: 1.15 ± 0.032	3.24IleArg: 3.24 ± 0.055	2.693IleSer: 2.693 ± 0.057	2.493IleThr: 2.493 ± 0.047	3.775IleVal: 3.775 ± 0.059	0.562IleTrp: 0.562 ± 0.021	1.088IleTyr: 1.088 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.857LysAla: 3.857 ± 0.073	0.137LysCys: 0.137 ± 0.011	1.499LysAsp: 1.499 ± 0.037	1.267LysGlu: 1.267 ± 0.039	0.808LysPhe: 0.808 ± 0.027	2.279LysGly: 2.279 ± 0.045	0.501LysHis: 0.501 ± 0.019	1.424LysIle: 1.424 ± 0.04	1.111LysLys: 1.111 ± 0.044	2.743LysLeu: 2.743 ± 0.05	0.616LysMet: 0.616 ± 0.029	0.771LysAsn: 0.771 ± 0.029	1.946LysPro: 1.946 ± 0.054	1.01LysGln: 1.01 ± 0.035	2.112LysArg: 2.112 ± 0.045	1.433LysSer: 1.433 ± 0.039	1.707LysThr: 1.707 ± 0.037	2.111LysVal: 2.111 ± 0.049	0.361LysTrp: 0.361 ± 0.018	0.582LysTyr: 0.582 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	15.138LeuAla: 15.138 ± 0.16	0.796LeuCys: 0.796 ± 0.026	5.672LeuAsp: 5.672 ± 0.074	4.846LeuGlu: 4.846 ± 0.075	3.372LeuPhe: 3.372 ± 0.061	8.164LeuGly: 8.164 ± 0.103	1.752LeuHis: 1.752 ± 0.041	4.066LeuIle: 4.066 ± 0.054	3.113LeuLys: 3.113 ± 0.067	9.178LeuLeu: 9.178 ± 0.121	2.212LeuMet: 2.212 ± 0.046	2.493LeuAsn: 2.493 ± 0.042	5.552LeuPro: 5.552 ± 0.068	2.822LeuGln: 2.822 ± 0.057	7.302LeuArg: 7.302 ± 0.094	5.407LeuSer: 5.407 ± 0.067	5.652LeuThr: 5.652 ± 0.078	7.236LeuVal: 7.236 ± 0.093	1.087LeuTrp: 1.087 ± 0.034	1.955LeuTyr: 1.955 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.587MetAla: 3.587 ± 0.057	0.165MetCys: 0.165 ± 0.014	1.078MetAsp: 1.078 ± 0.031	1.097MetGlu: 1.097 ± 0.038	0.728MetPhe: 0.728 ± 0.029	1.874MetGly: 1.874 ± 0.038	0.376MetHis: 0.376 ± 0.017	1.231MetIle: 1.231 ± 0.039	0.902MetLys: 0.902 ± 0.026	2.456MetLeu: 2.456 ± 0.045	0.653MetMet: 0.653 ± 0.023	0.756MetAsn: 0.756 ± 0.029	1.376MetPro: 1.376 ± 0.034	0.858MetGln: 0.858 ± 0.028	1.959MetArg: 1.959 ± 0.045	1.649MetSer: 1.649 ± 0.035	1.921MetThr: 1.921 ± 0.04	1.661MetVal: 1.661 ± 0.039	0.21MetTrp: 0.21 ± 0.013	0.32MetTyr: 0.32 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.451AsnAla: 3.451 ± 0.06	0.216AsnCys: 0.216 ± 0.014	1.446AsnAsp: 1.446 ± 0.042	1.076AsnGlu: 1.076 ± 0.034	0.91AsnPhe: 0.91 ± 0.029	2.511AsnGly: 2.511 ± 0.081	0.46AsnHis: 0.46 ± 0.02	1.244AsnIle: 1.244 ± 0.036	0.558AsnLys: 0.558 ± 0.025	2.437AsnLeu: 2.437 ± 0.05	0.586AsnMet: 0.586 ± 0.023	0.724AsnAsn: 0.724 ± 0.036	1.731AsnPro: 1.731 ± 0.04	0.713AsnGln: 0.713 ± 0.026	1.843AsnArg: 1.843 ± 0.045	1.124AsnSer: 1.124 ± 0.039	1.173AsnThr: 1.173 ± 0.039	1.93AsnVal: 1.93 ± 0.044	0.376AsnTrp: 0.376 ± 0.019	0.616AsnTyr: 0.616 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	8.317ProAla: 8.317 ± 0.118	0.333ProCys: 0.333 ± 0.017	4.027ProAsp: 4.027 ± 0.061	3.851ProGlu: 3.851 ± 0.063	1.894ProPhe: 1.894 ± 0.038	5.532ProGly: 5.532 ± 0.079	1.117ProHis: 1.117 ± 0.036	1.68ProIle: 1.68 ± 0.045	1.477ProLys: 1.477 ± 0.045	4.865ProLeu: 4.865 ± 0.068	1.298ProMet: 1.298 ± 0.039	1.122ProAsn: 1.122 ± 0.032	3.363ProPro: 3.363 ± 0.067	1.891ProGln: 1.891 ± 0.046	3.466ProArg: 3.466 ± 0.061	2.525ProSer: 2.525 ± 0.044	2.45ProThr: 2.45 ± 0.047	4.593ProVal: 4.593 ± 0.059	0.852ProTrp: 0.852 ± 0.032	1.061ProTyr: 1.061 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.608GlnAla: 4.608 ± 0.073	0.207GlnCys: 0.207 ± 0.015	1.478GlnAsp: 1.478 ± 0.037	1.515GlnGlu: 1.515 ± 0.04	1.009GlnPhe: 1.009 ± 0.03	2.577GlnGly: 2.577 ± 0.048	0.628GlnHis: 0.628 ± 0.021	1.734GlnIle: 1.734 ± 0.047	1.07GlnLys: 1.07 ± 0.034	2.969GlnLeu: 2.969 ± 0.056	0.822GlnMet: 0.822 ± 0.023	0.891GlnAsn: 0.891 ± 0.026	2.005GlnPro: 2.005 ± 0.045	1.331GlnGln: 1.331 ± 0.045	2.578GlnArg: 2.578 ± 0.049	1.484GlnSer: 1.484 ± 0.038	1.77GlnThr: 1.77 ± 0.041	2.199GlnVal: 2.199 ± 0.045	0.407GlnTrp: 0.407 ± 0.019	0.576GlnTyr: 0.576 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	9.852ArgAla: 9.852 ± 0.095	0.562ArgCys: 0.562 ± 0.027	4.479ArgAsp: 4.479 ± 0.069	4.145ArgGlu: 4.145 ± 0.06	2.97ArgPhe: 2.97 ± 0.055	5.381ArgGly: 5.381 ± 0.08	1.777ArgHis: 1.777 ± 0.048	4.147ArgIle: 4.147 ± 0.056	2.599ArgLys: 2.599 ± 0.049	8.61ArgLeu: 8.61 ± 0.099	2.08ArgMet: 2.08 ± 0.042	1.955ArgAsn: 1.955 ± 0.036	4.342ArgPro: 4.342 ± 0.076	3.056ArgGln: 3.056 ± 0.054	6.792ArgArg: 6.792 ± 0.119	3.538ArgSer: 3.538 ± 0.064	3.388ArgThr: 3.388 ± 0.056	5.087ArgVal: 5.087 ± 0.064	1.061ArgTrp: 1.061 ± 0.033	1.744ArgTyr: 1.744 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.325SerAla: 6.325 ± 0.075	0.397SerCys: 0.397 ± 0.017	2.669SerAsp: 2.669 ± 0.053	2.306SerGlu: 2.306 ± 0.051	2.07SerPhe: 2.07 ± 0.043	5.82SerGly: 5.82 ± 0.078	1.016SerHis: 1.016 ± 0.031	2.368SerIle: 2.368 ± 0.046	1.222SerLys: 1.222 ± 0.035	4.939SerLeu: 4.939 ± 0.071	1.177SerMet: 1.177 ± 0.034	1.193SerAsn: 1.193 ± 0.041	2.985SerPro: 2.985 ± 0.053	1.599SerGln: 1.599 ± 0.037	3.887SerArg: 3.887 ± 0.062	2.668SerSer: 2.668 ± 0.053	2.311SerThr: 2.311 ± 0.048	3.695SerVal: 3.695 ± 0.062	0.758SerTrp: 0.758 ± 0.027	1.12SerTyr: 1.12 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.242ThrAla: 6.242 ± 0.081	0.401ThrCys: 0.401 ± 0.018	2.543ThrAsp: 2.543 ± 0.046	2.112ThrGlu: 2.112 ± 0.041	1.772ThrPhe: 1.772 ± 0.034	5.384ThrGly: 5.384 ± 0.079	0.913ThrHis: 0.913 ± 0.03	2.432ThrIle: 2.432 ± 0.056	0.931ThrLys: 0.931 ± 0.027	5.318ThrLeu: 5.318 ± 0.07	1.108ThrMet: 1.108 ± 0.032	1.084ThrAsn: 1.084 ± 0.04	3.898ThrPro: 3.898 ± 0.062	1.311ThrGln: 1.311 ± 0.038	3.626ThrArg: 3.626 ± 0.052	2.554ThrSer: 2.554 ± 0.051	2.654ThrThr: 2.654 ± 0.054	3.896ThrVal: 3.896 ± 0.07	0.741ThrTrp: 0.741 ± 0.032	0.991ThrTyr: 0.991 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	10.498ValAla: 10.498 ± 0.115	0.655ValCys: 0.655 ± 0.022	4.26ValAsp: 4.26 ± 0.07	4.087ValGlu: 4.087 ± 0.058	2.722ValPhe: 2.722 ± 0.05	5.704ValGly: 5.704 ± 0.09	1.332ValHis: 1.332 ± 0.032	4.17ValIle: 4.17 ± 0.065	2.103ValLys: 2.103 ± 0.046	7.188ValLeu: 7.188 ± 0.081	1.91ValMet: 1.91 ± 0.044	2.158ValAsn: 2.158 ± 0.059	2.942ValPro: 2.942 ± 0.056	2.043ValGln: 2.043 ± 0.043	5.552ValArg: 5.552 ± 0.073	4.303ValSer: 4.303 ± 0.063	4.579ValThr: 4.579 ± 0.069	5.952ValVal: 5.952 ± 0.101	0.935ValTrp: 0.935 ± 0.03	1.444ValTyr: 1.444 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.273TrpAla: 1.273 ± 0.036	0.132TrpCys: 0.132 ± 0.012	0.64TrpAsp: 0.64 ± 0.024	0.546TrpGlu: 0.546 ± 0.022	0.579TrpPhe: 0.579 ± 0.029	1.009TrpGly: 1.009 ± 0.032	0.247TrpHis: 0.247 ± 0.014	0.621TrpIle: 0.621 ± 0.025	0.427TrpLys: 0.427 ± 0.023	1.77TrpLeu: 1.77 ± 0.046	0.366TrpMet: 0.366 ± 0.016	0.435TrpAsn: 0.435 ± 0.02	0.767TrpPro: 0.767 ± 0.026	0.482TrpGln: 0.482 ± 0.02	1.592TrpArg: 1.592 ± 0.041	0.842TrpSer: 0.842 ± 0.028	0.816TrpThr: 0.816 ± 0.032	0.724TrpVal: 0.724 ± 0.027	0.208TrpTrp: 0.208 ± 0.012	0.257TrpTyr: 0.257 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.584TyrAla: 2.584 ± 0.052	0.224TyrCys: 0.224 ± 0.014	1.315TyrAsp: 1.315 ± 0.04	1.082TyrGlu: 1.082 ± 0.026	0.813TyrPhe: 0.813 ± 0.029	2.136TyrGly: 2.136 ± 0.041	0.394TyrHis: 0.394 ± 0.019	0.82TyrIle: 0.82 ± 0.031	0.507TyrLys: 0.507 ± 0.023	2.049TyrLeu: 2.049 ± 0.04	0.489TyrMet: 0.489 ± 0.019	0.547TyrAsn: 0.547 ± 0.023	0.954TyrPro: 0.954 ± 0.028	0.642TyrGln: 0.642 ± 0.023	1.661TyrArg: 1.661 ± 0.038	0.967TyrSer: 0.967 ± 0.031	0.95TyrThr: 0.95 ± 0.038	1.625TyrVal: 1.625 ± 0.043	0.34TyrTrp: 0.34 ± 0.018	0.566TyrTyr: 0.566 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3613 proteins (1159828 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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