Amino acid dipepetide frequency for Prunus persica (Peach) (Amygdalus persica)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.086AlaAla: 6.086 ± 0.026
1.295AlaCys: 1.295 ± 0.011
3.112AlaAsp: 3.112 ± 0.015
4.135AlaGlu: 4.135 ± 0.019
2.778AlaPhe: 2.778 ± 0.015
3.975AlaGly: 3.975 ± 0.016
1.386AlaHis: 1.386 ± 0.009
3.704AlaIle: 3.704 ± 0.017
3.838AlaLys: 3.838 ± 0.016
6.737AlaLeu: 6.737 ± 0.026
1.691AlaMet: 1.691 ± 0.01
2.586AlaAsn: 2.586 ± 0.013
2.78AlaPro: 2.78 ± 0.014
2.164AlaGln: 2.164 ± 0.012
3.287AlaArg: 3.287 ± 0.015
6.08AlaSer: 6.08 ± 0.02
3.496AlaThr: 3.496 ± 0.016
4.714AlaVal: 4.714 ± 0.018
0.775AlaTrp: 0.775 ± 0.007
1.829AlaTyr: 1.829 ± 0.011
0.0AlaXaa: 0.0 ± 0.0
Cys
1.012CysAla: 1.012 ± 0.008
0.558CysCys: 0.558 ± 0.008
0.853CysAsp: 0.853 ± 0.008
0.909CysGlu: 0.909 ± 0.008
0.94CysPhe: 0.94 ± 0.008
1.393CysGly: 1.393 ± 0.011
0.509CysHis: 0.509 ± 0.005
1.073CysIle: 1.073 ± 0.007
1.183CysLys: 1.183 ± 0.01
1.972CysLeu: 1.972 ± 0.014
0.482CysMet: 0.482 ± 0.006
0.887CysAsn: 0.887 ± 0.008
0.938CysPro: 0.938 ± 0.01
0.651CysGln: 0.651 ± 0.007
1.043CysArg: 1.043 ± 0.008
1.899CysSer: 1.899 ± 0.013
0.914CysThr: 0.914 ± 0.007
1.069CysVal: 1.069 ± 0.009
0.262CysTrp: 0.262 ± 0.004
0.542CysTyr: 0.542 ± 0.006
0.0CysXaa: 0.0 ± 0.0
Asp
3.452AspAla: 3.452 ± 0.016
0.961AspCys: 0.961 ± 0.008
3.573AspAsp: 3.573 ± 0.02
3.921AspGlu: 3.921 ± 0.019
2.379AspPhe: 2.379 ± 0.011
3.805AspGly: 3.805 ± 0.015
1.305AspHis: 1.305 ± 0.009
3.017AspIle: 3.017 ± 0.015
2.721AspLys: 2.721 ± 0.014
5.128AspLeu: 5.128 ± 0.02
1.298AspMet: 1.298 ± 0.009
2.086AspAsn: 2.086 ± 0.011
2.6AspPro: 2.6 ± 0.014
1.863AspGln: 1.863 ± 0.012
2.401AspArg: 2.401 ± 0.015
4.243AspSer: 4.243 ± 0.021
2.186AspThr: 2.186 ± 0.011
3.639AspVal: 3.639 ± 0.015
0.707AspTrp: 0.707 ± 0.007
1.528AspTyr: 1.528 ± 0.009
0.0AspXaa: 0.0 ± 0.0
Glu
4.824GluAla: 4.824 ± 0.02
0.928GluCys: 0.928 ± 0.008
3.97GluAsp: 3.97 ± 0.018
6.008GluGlu: 6.008 ± 0.034
2.381GluPhe: 2.381 ± 0.012
3.793GluGly: 3.793 ± 0.014
1.316GluHis: 1.316 ± 0.009
3.68GluIle: 3.68 ± 0.016
4.758GluLys: 4.758 ± 0.023
6.03GluLeu: 6.03 ± 0.026
1.698GluMet: 1.698 ± 0.011
3.113GluAsn: 3.113 ± 0.017
2.199GluPro: 2.199 ± 0.012
2.207GluGln: 2.207 ± 0.014
3.45GluArg: 3.45 ± 0.018
4.563GluSer: 4.563 ± 0.02
3.055GluThr: 3.055 ± 0.015
4.202GluVal: 4.202 ± 0.017
0.775GluTrp: 0.775 ± 0.006
1.634GluTyr: 1.634 ± 0.011
0.0GluXaa: 0.0 ± 0.0
Phe
2.439PheAla: 2.439 ± 0.012
0.932PheCys: 0.932 ± 0.008
2.313PheAsp: 2.313 ± 0.013
2.305PheGlu: 2.305 ± 0.011
1.958PhePhe: 1.958 ± 0.015
3.079PheGly: 3.079 ± 0.019
1.112PheHis: 1.112 ± 0.009
2.076PheIle: 2.076 ± 0.013
2.145PheLys: 2.145 ± 0.011
4.365PheLeu: 4.365 ± 0.02
0.957PheMet: 0.957 ± 0.006
1.784PheAsn: 1.784 ± 0.012
2.092PhePro: 2.092 ± 0.012
1.621PheGln: 1.621 ± 0.01
2.026PheArg: 2.026 ± 0.011
4.209PheSer: 4.209 ± 0.016
1.965PheThr: 1.965 ± 0.012
2.762PheVal: 2.762 ± 0.015
0.598PheTrp: 0.598 ± 0.006
1.281PheTyr: 1.281 ± 0.009
0.0PheXaa: 0.0 ± 0.0
Gly
3.803GlyAla: 3.803 ± 0.016
1.331GlyCys: 1.331 ± 0.01
3.348GlyAsp: 3.348 ± 0.017
3.551GlyGlu: 3.551 ± 0.014
3.159GlyPhe: 3.159 ± 0.015
5.172GlyGly: 5.172 ± 0.034
1.546GlyHis: 1.546 ± 0.01
3.64GlyIle: 3.64 ± 0.015
4.058GlyLys: 4.058 ± 0.018
6.073GlyLeu: 6.073 ± 0.018
1.503GlyMet: 1.503 ± 0.01
3.167GlyAsn: 3.167 ± 0.016
2.484GlyPro: 2.484 ± 0.016
2.16GlyGln: 2.16 ± 0.014
3.567GlyArg: 3.567 ± 0.018
6.103GlySer: 6.103 ± 0.019
3.266GlyThr: 3.266 ± 0.015
4.153GlyVal: 4.153 ± 0.016
0.878GlyTrp: 0.878 ± 0.007
2.015GlyTyr: 2.015 ± 0.013
0.0GlyXaa: 0.0 ± 0.0
His
1.463HisAla: 1.463 ± 0.009
0.535HisCys: 0.535 ± 0.007
1.202HisAsp: 1.202 ± 0.008
1.364HisGlu: 1.364 ± 0.01
1.094HisPhe: 1.094 ± 0.009
1.761HisGly: 1.761 ± 0.011
1.004HisHis: 1.004 ± 0.011
1.269HisIle: 1.269 ± 0.008
1.262HisLys: 1.262 ± 0.008
2.587HisLeu: 2.587 ± 0.014
0.579HisMet: 0.579 ± 0.006
1.025HisAsn: 1.025 ± 0.008
1.417HisPro: 1.417 ± 0.009
1.103HisGln: 1.103 ± 0.009
1.35HisArg: 1.35 ± 0.008
2.009HisSer: 2.009 ± 0.011
1.001HisThr: 1.001 ± 0.009
1.588HisVal: 1.588 ± 0.01
0.316HisTrp: 0.316 ± 0.005
0.715HisTyr: 0.715 ± 0.007
0.0HisXaa: 0.0 ± 0.0
Ile
3.502IleAla: 3.502 ± 0.015
1.118IleCys: 1.118 ± 0.008
2.806IleAsp: 2.806 ± 0.014
3.173IleGlu: 3.173 ± 0.015
2.318IlePhe: 2.318 ± 0.013
3.369IleGly: 3.369 ± 0.016
1.311IleHis: 1.311 ± 0.009
2.73IleIle: 2.73 ± 0.016
2.877IleLys: 2.877 ± 0.014
5.205IleLeu: 5.205 ± 0.022
1.126IleMet: 1.126 ± 0.009
2.201IleAsn: 2.201 ± 0.012
2.963IlePro: 2.963 ± 0.016
2.024IleGln: 2.024 ± 0.012
2.614IleArg: 2.614 ± 0.013
4.984IleSer: 4.984 ± 0.017
2.541IleThr: 2.541 ± 0.013
3.401IleVal: 3.401 ± 0.015
0.729IleTrp: 0.729 ± 0.008
1.503IleTyr: 1.503 ± 0.011
0.0IleXaa: 0.0 ± 0.0
Lys
4.01LysAla: 4.01 ± 0.02
1.002LysCys: 1.002 ± 0.008
3.304LysAsp: 3.304 ± 0.015
4.665LysGlu: 4.665 ± 0.028
2.203LysPhe: 2.203 ± 0.012
3.604LysGly: 3.604 ± 0.016
1.388LysHis: 1.388 ± 0.009
3.21LysIle: 3.21 ± 0.014
4.594LysLys: 4.594 ± 0.025
6.134LysLeu: 6.134 ± 0.025
1.495LysMet: 1.495 ± 0.01
2.713LysAsn: 2.713 ± 0.012
2.744LysPro: 2.744 ± 0.016
2.374LysGln: 2.374 ± 0.015
3.621LysArg: 3.621 ± 0.015
4.672LysSer: 4.672 ± 0.019
2.885LysThr: 2.885 ± 0.014
3.887LysVal: 3.887 ± 0.016
0.789LysTrp: 0.789 ± 0.006
1.645LysTyr: 1.645 ± 0.01
0.0LysXaa: 0.0 ± 0.0
Leu
6.491LeuAla: 6.491 ± 0.023
1.95LeuCys: 1.95 ± 0.011
5.253LeuAsp: 5.253 ± 0.02
6.539LeuGlu: 6.539 ± 0.026
3.879LeuPhe: 3.879 ± 0.018
5.918LeuGly: 5.918 ± 0.02
2.703LeuHis: 2.703 ± 0.014
4.673LeuIle: 4.673 ± 0.021
6.271LeuLys: 6.271 ± 0.022
10.146LeuLeu: 10.146 ± 0.032
2.124LeuMet: 2.124 ± 0.012
4.052LeuAsn: 4.052 ± 0.016
5.323LeuPro: 5.323 ± 0.022
4.562LeuGln: 4.562 ± 0.018
5.434LeuArg: 5.434 ± 0.021
8.981LeuSer: 8.981 ± 0.033
4.534LeuThr: 4.534 ± 0.017
6.467LeuVal: 6.467 ± 0.024
1.189LeuTrp: 1.189 ± 0.009
2.566LeuTyr: 2.566 ± 0.013
0.0LeuXaa: 0.0 ± 0.0
Met
2.022MetAla: 2.022 ± 0.012
0.354MetCys: 0.354 ± 0.004
1.428MetAsp: 1.428 ± 0.01
1.919MetGlu: 1.919 ± 0.011
0.801MetPhe: 0.801 ± 0.007
1.585MetGly: 1.585 ± 0.009
0.561MetHis: 0.561 ± 0.005
1.116MetIle: 1.116 ± 0.008
1.583MetLys: 1.583 ± 0.01
2.208MetLeu: 2.208 ± 0.012
0.64MetMet: 0.64 ± 0.007
0.999MetAsn: 0.999 ± 0.009
1.062MetPro: 1.062 ± 0.008
0.948MetGln: 0.948 ± 0.008
1.209MetArg: 1.209 ± 0.01
1.767MetSer: 1.767 ± 0.011
1.007MetThr: 1.007 ± 0.008
1.625MetVal: 1.625 ± 0.01
0.261MetTrp: 0.261 ± 0.004
0.571MetTyr: 0.571 ± 0.006
0.0MetXaa: 0.0 ± 0.0
Asn
2.673AsnAla: 2.673 ± 0.012
0.906AsnCys: 0.906 ± 0.009
2.101AsnAsp: 2.101 ± 0.012
2.521AsnGlu: 2.521 ± 0.014
1.987AsnPhe: 1.987 ± 0.012
3.248AsnGly: 3.248 ± 0.017
1.141AsnHis: 1.141 ± 0.008
2.482AsnIle: 2.482 ± 0.013
2.474AsnLys: 2.474 ± 0.013
4.849AsnLeu: 4.849 ± 0.026
1.108AsnMet: 1.108 ± 0.009
2.343AsnAsn: 2.343 ± 0.015
2.372AsnPro: 2.372 ± 0.014
1.782AsnGln: 1.782 ± 0.012
1.988AsnArg: 1.988 ± 0.014
4.095AsnSer: 4.095 ± 0.017
1.982AsnThr: 1.982 ± 0.013
2.818AsnVal: 2.818 ± 0.014
0.591AsnTrp: 0.591 ± 0.005
1.331AsnTyr: 1.331 ± 0.009
0.0AsnXaa: 0.0 ± 0.0
Pro
2.962ProAla: 2.962 ± 0.014
0.805ProCys: 0.805 ± 0.008
2.449ProAsp: 2.449 ± 0.012
3.161ProGlu: 3.161 ± 0.015
1.959ProPhe: 1.959 ± 0.009
2.668ProGly: 2.668 ± 0.015
1.184ProHis: 1.184 ± 0.008
2.353ProIle: 2.353 ± 0.012
2.854ProLys: 2.854 ± 0.015
4.356ProLeu: 4.356 ± 0.019
0.939ProMet: 0.939 ± 0.008
2.406ProAsn: 2.406 ± 0.015
3.706ProPro: 3.706 ± 0.037
1.944ProGln: 1.944 ± 0.014
2.288ProArg: 2.288 ± 0.014
5.214ProSer: 5.214 ± 0.02
2.611ProThr: 2.611 ± 0.015
3.049ProVal: 3.049 ± 0.016
0.587ProTrp: 0.587 ± 0.006
1.312ProTyr: 1.312 ± 0.009
0.0ProXaa: 0.0 ± 0.0
Gln
2.482GlnAla: 2.482 ± 0.014
0.613GlnCys: 0.613 ± 0.006
1.745GlnAsp: 1.745 ± 0.012
2.474GlnGlu: 2.474 ± 0.013
1.435GlnPhe: 1.435 ± 0.009
2.178GlnGly: 2.178 ± 0.012
1.002GlnHis: 1.002 ± 0.009
2.045GlnIle: 2.045 ± 0.012
2.408GlnLys: 2.408 ± 0.014
3.895GlnLeu: 3.895 ± 0.018
0.986GlnMet: 0.986 ± 0.008
1.908GlnAsn: 1.908 ± 0.012
1.838GlnPro: 1.838 ± 0.013
2.265GlnGln: 2.265 ± 0.034
2.163GlnArg: 2.163 ± 0.012
3.085GlnSer: 3.085 ± 0.018
1.82GlnThr: 1.82 ± 0.011
2.467GlnVal: 2.467 ± 0.014
0.474GlnTrp: 0.474 ± 0.005
0.955GlnTyr: 0.955 ± 0.008
0.0GlnXaa: 0.0 ± 0.0
Arg
3.177ArgAla: 3.177 ± 0.017
0.983ArgCys: 0.983 ± 0.009
2.637ArgAsp: 2.637 ± 0.014
3.332ArgGlu: 3.332 ± 0.016
2.156ArgPhe: 2.156 ± 0.012
3.128ArgGly: 3.128 ± 0.015
1.31ArgHis: 1.31 ± 0.009
2.776ArgIle: 2.776 ± 0.013
3.784ArgLys: 3.784 ± 0.019
5.081ArgLeu: 5.081 ± 0.018
1.272ArgMet: 1.272 ± 0.009
2.476ArgAsn: 2.476 ± 0.011
2.313ArgPro: 2.313 ± 0.014
1.871ArgGln: 1.871 ± 0.012
3.71ArgArg: 3.71 ± 0.019
4.302ArgSer: 4.302 ± 0.021
2.46ArgThr: 2.46 ± 0.012
3.29ArgVal: 3.29 ± 0.013
0.723ArgTrp: 0.723 ± 0.007
1.425ArgTyr: 1.425 ± 0.01
0.0ArgXaa: 0.0 ± 0.0
Ser
5.435SerAla: 5.435 ± 0.02
1.808SerCys: 1.808 ± 0.015
4.472SerAsp: 4.472 ± 0.019
4.953SerGlu: 4.953 ± 0.021
4.01SerPhe: 4.01 ± 0.015
6.027SerGly: 6.027 ± 0.022
2.138SerHis: 2.138 ± 0.011
4.579SerIle: 4.579 ± 0.019
5.076SerLys: 5.076 ± 0.021
9.059SerLeu: 9.059 ± 0.031
2.102SerMet: 2.102 ± 0.013
4.211SerAsn: 4.211 ± 0.02
4.469SerPro: 4.469 ± 0.022
3.184SerGln: 3.184 ± 0.015
4.419SerArg: 4.419 ± 0.018
11.223SerSer: 11.223 ± 0.046
4.791SerThr: 4.791 ± 0.02
5.337SerVal: 5.337 ± 0.018
1.166SerTrp: 1.166 ± 0.009
2.352SerTyr: 2.352 ± 0.012
0.0SerXaa: 0.0 ± 0.0
Thr
3.315ThrAla: 3.315 ± 0.015
0.942ThrCys: 0.942 ± 0.009
2.293ThrAsp: 2.293 ± 0.013
2.858ThrGlu: 2.858 ± 0.014
2.033ThrPhe: 2.033 ± 0.012
3.209ThrGly: 3.209 ± 0.014
1.093ThrHis: 1.093 ± 0.009
2.655ThrIle: 2.655 ± 0.016
2.721ThrLys: 2.721 ± 0.013
4.719ThrLeu: 4.719 ± 0.018
1.129ThrMet: 1.129 ± 0.008
2.148ThrAsn: 2.148 ± 0.013
2.52ThrPro: 2.52 ± 0.014
1.686ThrGln: 1.686 ± 0.011
2.32ThrArg: 2.32 ± 0.012
4.664ThrSer: 4.664 ± 0.02
2.963ThrThr: 2.963 ± 0.017
3.258ThrVal: 3.258 ± 0.015
0.651ThrTrp: 0.651 ± 0.006
1.38ThrTyr: 1.38 ± 0.009
0.0ThrXaa: 0.0 ± 0.0
Val
4.734ValAla: 4.734 ± 0.018
1.191ValCys: 1.191 ± 0.01
3.724ValAsp: 3.724 ± 0.015
4.429ValGlu: 4.429 ± 0.018
2.695ValPhe: 2.695 ± 0.013
4.226ValGly: 4.226 ± 0.018
1.596ValHis: 1.596 ± 0.01
3.296ValIle: 3.296 ± 0.015
3.842ValLys: 3.842 ± 0.018
6.45ValLeu: 6.45 ± 0.023
1.461ValMet: 1.461 ± 0.009
2.627ValAsn: 2.627 ± 0.014
3.235ValPro: 3.235 ± 0.015
2.414ValGln: 2.414 ± 0.014
3.098ValArg: 3.098 ± 0.012
5.481ValSer: 5.481 ± 0.019
3.138ValThr: 3.138 ± 0.016
4.873ValVal: 4.873 ± 0.021
0.772ValTrp: 0.772 ± 0.007
1.912ValTyr: 1.912 ± 0.012
0.0ValXaa: 0.0 ± 0.0
Trp
0.765TrpAla: 0.765 ± 0.007
0.247TrpCys: 0.247 ± 0.004
0.716TrpAsp: 0.716 ± 0.007
0.776TrpGlu: 0.776 ± 0.007
0.573TrpPhe: 0.573 ± 0.006
0.752TrpGly: 0.752 ± 0.008
0.31TrpHis: 0.31 ± 0.004
0.669TrpIle: 0.669 ± 0.007
0.968TrpLys: 0.968 ± 0.008
1.253TrpLeu: 1.253 ± 0.009
0.33TrpMet: 0.33 ± 0.005
0.711TrpAsn: 0.711 ± 0.007
0.507TrpPro: 0.507 ± 0.006
0.439TrpGln: 0.439 ± 0.005
0.806TrpArg: 0.806 ± 0.007
0.972TrpSer: 0.972 ± 0.009
0.647TrpThr: 0.647 ± 0.006
0.859TrpVal: 0.859 ± 0.008
0.249TrpTrp: 0.249 ± 0.004
0.338TrpTyr: 0.338 ± 0.005
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.799TyrAla: 1.799 ± 0.01
0.632TyrCys: 0.632 ± 0.007
1.515TyrAsp: 1.515 ± 0.011
1.59TyrGlu: 1.59 ± 0.009
1.279TyrPhe: 1.279 ± 0.01
2.086TyrGly: 2.086 ± 0.013
0.731TyrHis: 0.731 ± 0.007
1.453TyrIle: 1.453 ± 0.011
1.522TyrLys: 1.522 ± 0.008
2.807TyrLeu: 2.807 ± 0.016
0.744TyrMet: 0.744 ± 0.006
1.349TyrAsn: 1.349 ± 0.011
1.243TyrPro: 1.243 ± 0.01
0.975TyrGln: 0.975 ± 0.008
1.414TyrArg: 1.414 ± 0.01
2.267TyrSer: 2.267 ± 0.013
1.293TyrThr: 1.293 ± 0.01
1.735TyrVal: 1.735 ± 0.011
0.398TyrTrp: 0.398 ± 0.005
0.94TyrTyr: 0.94 ± 0.008
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 38732 proteins (17259961 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski