Amino acid dipepetide frequency for Rodent Torque teno virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.195AlaAla: 9.195 ± 6.839
1.149AlaCys: 1.149 ± 1.864
2.299AlaAsp: 2.299 ± 1.489
1.149AlaGlu: 1.149 ± 1.817
2.299AlaPhe: 2.299 ± 1.235
3.448AlaGly: 3.448 ± 1.853
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
3.448AlaLys: 3.448 ± 1.911
2.299AlaLeu: 2.299 ± 2.529
1.149AlaMet: 1.149 ± 2.369
1.149AlaAsn: 1.149 ± 0.618
2.299AlaPro: 2.299 ± 3.634
5.747AlaGln: 5.747 ± 2.784
5.747AlaArg: 5.747 ± 1.737
2.299AlaSer: 2.299 ± 3.634
4.598AlaThr: 4.598 ± 1.294
2.299AlaVal: 2.299 ± 1.489
2.299AlaTrp: 2.299 ± 1.484
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.149CysAla: 1.149 ± 0.618
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.149CysPhe: 1.149 ± 0.618
0.0CysGly: 0.0 ± 0.0
2.299CysHis: 2.299 ± 1.489
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.299CysLeu: 2.299 ± 1.235
1.149CysMet: 1.149 ± 0.618
0.0CysAsn: 0.0 ± 0.0
1.149CysPro: 1.149 ± 0.618
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.149CysSer: 1.149 ± 1.864
3.448CysThr: 3.448 ± 1.312
0.0CysVal: 0.0 ± 0.0
1.149CysTrp: 1.149 ± 0.618
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
2.299AspAsp: 2.299 ± 1.235
2.299AspGlu: 2.299 ± 1.235
2.299AspPhe: 2.299 ± 1.484
6.897AspGly: 6.897 ± 2.353
0.0AspHis: 0.0 ± 0.0
2.299AspIle: 2.299 ± 1.235
0.0AspLys: 0.0 ± 0.0
5.747AspLeu: 5.747 ± 1.864
3.448AspMet: 3.448 ± 1.365
1.149AspAsn: 1.149 ± 1.864
1.149AspPro: 1.149 ± 0.618
2.299AspGln: 2.299 ± 1.489
0.0AspArg: 0.0 ± 0.0
4.598AspSer: 4.598 ± 5.66
1.149AspThr: 1.149 ± 1.817
1.149AspVal: 1.149 ± 0.618
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.598GluAla: 4.598 ± 2.967
0.0GluCys: 0.0 ± 0.0
2.299GluAsp: 2.299 ± 1.235
14.943GluGlu: 14.943 ± 6.359
1.149GluPhe: 1.149 ± 1.817
3.448GluGly: 3.448 ± 1.312
2.299GluHis: 2.299 ± 1.235
2.299GluIle: 2.299 ± 3.634
1.149GluLys: 1.149 ± 1.864
4.598GluLeu: 4.598 ± 3.419
2.299GluMet: 2.299 ± 1.489
4.598GluAsn: 4.598 ± 2.978
3.448GluPro: 3.448 ± 1.312
4.598GluGln: 4.598 ± 3.472
4.598GluArg: 4.598 ± 1.513
3.448GluSer: 3.448 ± 1.911
5.747GluThr: 5.747 ± 4.792
2.299GluVal: 2.299 ± 1.489
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.149PheAla: 1.149 ± 0.618
1.149PheCys: 1.149 ± 0.618
1.149PheAsp: 1.149 ± 1.817
2.299PheGlu: 2.299 ± 1.484
0.0PhePhe: 0.0 ± 0.0
2.299PheGly: 2.299 ± 1.235
1.149PheHis: 1.149 ± 1.864
0.0PheIle: 0.0 ± 0.0
1.149PheLys: 1.149 ± 0.618
4.598PheLeu: 4.598 ± 1.41
1.149PheMet: 1.149 ± 0.618
0.0PheAsn: 0.0 ± 0.0
3.448PhePro: 3.448 ± 1.853
4.598PheGln: 4.598 ± 1.513
3.448PheArg: 3.448 ± 1.853
3.448PheSer: 3.448 ± 4.054
1.149PheThr: 1.149 ± 0.618
0.0PheVal: 0.0 ± 0.0
4.598PheTrp: 4.598 ± 1.513
4.598PheTyr: 4.598 ± 2.47
0.0PheXaa: 0.0 ± 0.0
Gly
3.448GlyAla: 3.448 ± 3.26
1.149GlyCys: 1.149 ± 0.618
2.299GlyAsp: 2.299 ± 2.529
3.448GlyGlu: 3.448 ± 1.911
6.897GlyPhe: 6.897 ± 2.193
12.644GlyGly: 12.644 ± 6.956
0.0GlyHis: 0.0 ± 0.0
2.299GlyIle: 2.299 ± 1.235
1.149GlyLys: 1.149 ± 1.864
2.299GlyLeu: 2.299 ± 1.235
0.0GlyMet: 0.0 ± 0.0
5.747GlyAsn: 5.747 ± 3.088
4.598GlyPro: 4.598 ± 2.47
3.448GlyGln: 3.448 ± 1.853
4.598GlyArg: 4.598 ± 1.294
3.448GlySer: 3.448 ± 1.853
9.195GlyThr: 9.195 ± 4.94
4.598GlyVal: 4.598 ± 1.41
2.299GlyTrp: 2.299 ± 1.489
2.299GlyTyr: 2.299 ± 1.235
0.0GlyXaa: 0.0 ± 0.0
His
1.149HisAla: 1.149 ± 1.864
1.149HisCys: 1.149 ± 0.618
0.0HisAsp: 0.0 ± 0.0
1.149HisGlu: 1.149 ± 0.618
0.0HisPhe: 0.0 ± 0.0
2.299HisGly: 2.299 ± 1.484
1.149HisHis: 1.149 ± 0.618
1.149HisIle: 1.149 ± 0.618
2.299HisLys: 2.299 ± 1.235
2.299HisLeu: 2.299 ± 2.529
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.149HisPro: 1.149 ± 0.618
0.0HisGln: 0.0 ± 0.0
2.299HisArg: 2.299 ± 1.235
4.598HisSer: 4.598 ± 1.41
1.149HisThr: 1.149 ± 0.618
2.299HisVal: 2.299 ± 1.235
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
1.149IleGlu: 1.149 ± 0.618
2.299IlePhe: 2.299 ± 1.489
1.149IleGly: 1.149 ± 0.618
1.149IleHis: 1.149 ± 1.817
2.299IleIle: 2.299 ± 1.484
4.598IleLys: 4.598 ± 1.513
4.598IleLeu: 4.598 ± 5.172
2.299IleMet: 2.299 ± 1.103
2.299IleAsn: 2.299 ± 1.484
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
5.747IleArg: 5.747 ± 2.784
2.299IleSer: 2.299 ± 1.235
3.448IleThr: 3.448 ± 1.853
1.149IleVal: 1.149 ± 0.618
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.598LysAla: 4.598 ± 5.66
0.0LysCys: 0.0 ± 0.0
2.299LysAsp: 2.299 ± 1.484
2.299LysGlu: 2.299 ± 3.729
4.598LysPhe: 4.598 ± 1.294
1.149LysGly: 1.149 ± 0.618
1.149LysHis: 1.149 ± 0.618
2.299LysIle: 2.299 ± 1.489
4.598LysLys: 4.598 ± 5.065
2.299LysLeu: 2.299 ± 1.235
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
3.448LysPro: 3.448 ± 1.365
2.299LysGln: 2.299 ± 1.235
5.747LysArg: 5.747 ± 3.088
1.149LysSer: 1.149 ± 0.618
5.747LysThr: 5.747 ± 0.678
0.0LysVal: 0.0 ± 0.0
2.299LysTrp: 2.299 ± 1.235
2.299LysTyr: 2.299 ± 1.235
0.0LysXaa: 0.0 ± 0.0
Leu
2.299LeuAla: 2.299 ± 3.634
1.149LeuCys: 1.149 ± 0.618
8.046LeuAsp: 8.046 ± 2.713
3.448LeuGlu: 3.448 ± 3.317
3.448LeuPhe: 3.448 ± 1.853
11.494LeuGly: 11.494 ± 2.957
1.149LeuHis: 1.149 ± 0.618
2.299LeuIle: 2.299 ± 1.484
3.448LeuLys: 3.448 ± 1.365
16.092LeuLeu: 16.092 ± 4.826
1.149LeuMet: 1.149 ± 1.262
2.299LeuAsn: 2.299 ± 1.484
8.046LeuPro: 8.046 ± 6.968
3.448LeuGln: 3.448 ± 1.911
5.747LeuArg: 5.747 ± 3.088
5.747LeuSer: 5.747 ± 1.737
3.448LeuThr: 3.448 ± 1.312
2.299LeuVal: 2.299 ± 1.235
3.448LeuTrp: 3.448 ± 1.312
2.299LeuTyr: 2.299 ± 1.484
0.0LeuXaa: 0.0 ± 0.0
Met
3.448MetAla: 3.448 ± 1.312
1.149MetCys: 1.149 ± 0.618
1.149MetAsp: 1.149 ± 0.618
2.299MetGlu: 2.299 ± 1.489
0.0MetPhe: 0.0 ± 0.0
1.149MetGly: 1.149 ± 0.618
1.149MetHis: 1.149 ± 0.618
0.0MetIle: 0.0 ± 0.0
3.448MetLys: 3.448 ± 1.312
1.149MetLeu: 1.149 ± 1.817
1.149MetMet: 1.149 ± 0.618
1.149MetAsn: 1.149 ± 0.618
0.0MetPro: 0.0 ± 0.0
1.149MetGln: 1.149 ± 0.618
0.0MetArg: 0.0 ± 0.0
1.149MetSer: 1.149 ± 1.817
2.299MetThr: 2.299 ± 1.235
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.448MetTyr: 3.448 ± 1.312
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
3.448AsnAsp: 3.448 ± 1.365
1.149AsnGlu: 1.149 ± 0.618
1.149AsnPhe: 1.149 ± 0.618
1.149AsnGly: 1.149 ± 1.864
0.0AsnHis: 0.0 ± 0.0
1.149AsnIle: 1.149 ± 0.618
3.448AsnLys: 3.448 ± 1.312
3.448AsnLeu: 3.448 ± 1.853
1.149AsnMet: 1.149 ± 0.618
1.149AsnAsn: 1.149 ± 0.618
4.598AsnPro: 4.598 ± 2.47
2.299AsnGln: 2.299 ± 1.489
1.149AsnArg: 1.149 ± 1.817
1.149AsnSer: 1.149 ± 0.618
2.299AsnThr: 2.299 ± 1.235
0.0AsnVal: 0.0 ± 0.0
2.299AsnTrp: 2.299 ± 1.484
2.299AsnTyr: 2.299 ± 1.235
0.0AsnXaa: 0.0 ± 0.0
Pro
2.299ProAla: 2.299 ± 1.489
1.149ProCys: 1.149 ± 0.618
1.149ProAsp: 1.149 ± 1.864
6.897ProGlu: 6.897 ± 5.828
2.299ProPhe: 2.299 ± 1.484
5.747ProGly: 5.747 ± 1.737
0.0ProHis: 0.0 ± 0.0
3.448ProIle: 3.448 ± 1.365
2.299ProLys: 2.299 ± 1.484
9.195ProLeu: 9.195 ± 1.469
1.149ProMet: 1.149 ± 0.618
1.149ProAsn: 1.149 ± 0.618
4.598ProPro: 4.598 ± 1.513
4.598ProGln: 4.598 ± 1.294
4.598ProArg: 4.598 ± 2.978
8.046ProSer: 8.046 ± 1.868
4.598ProThr: 4.598 ± 1.513
6.897ProVal: 6.897 ± 2.193
3.448ProTrp: 3.448 ± 1.853
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.598GlnAla: 4.598 ± 5.172
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.299GlnGlu: 2.299 ± 1.489
3.448GlnPhe: 3.448 ± 1.853
3.448GlnGly: 3.448 ± 1.853
2.299GlnHis: 2.299 ± 1.484
0.0GlnIle: 0.0 ± 0.0
6.897GlnLys: 6.897 ± 2.353
4.598GlnLeu: 4.598 ± 1.513
1.149GlnMet: 1.149 ± 0.618
0.0GlnAsn: 0.0 ± 0.0
5.747GlnPro: 5.747 ± 1.737
5.747GlnGln: 5.747 ± 7.575
2.299GlnArg: 2.299 ± 1.484
3.448GlnSer: 3.448 ± 1.911
1.149GlnThr: 1.149 ± 0.618
0.0GlnVal: 0.0 ± 0.0
2.299GlnTrp: 2.299 ± 1.235
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.598ArgAla: 4.598 ± 1.513
2.299ArgCys: 2.299 ± 1.489
1.149ArgAsp: 1.149 ± 0.618
3.448ArgGlu: 3.448 ± 3.989
0.0ArgPhe: 0.0 ± 0.0
3.448ArgGly: 3.448 ± 1.853
3.448ArgHis: 3.448 ± 1.853
3.448ArgIle: 3.448 ± 1.853
6.897ArgLys: 6.897 ± 2.329
5.747ArgLeu: 5.747 ± 1.737
0.0ArgMet: 0.0 ± 0.0
2.299ArgAsn: 2.299 ± 1.484
10.345ArgPro: 10.345 ± 1.261
0.0ArgGln: 0.0 ± 0.0
26.437ArgArg: 26.437 ± 4.163
3.448ArgSer: 3.448 ± 1.853
2.299ArgThr: 2.299 ± 1.484
1.149ArgVal: 1.149 ± 0.618
4.598ArgTrp: 4.598 ± 2.47
4.598ArgTyr: 4.598 ± 2.47
0.0ArgXaa: 0.0 ± 0.0
Ser
3.448SerAla: 3.448 ± 1.911
0.0SerCys: 0.0 ± 0.0
2.299SerAsp: 2.299 ± 3.634
2.299SerGlu: 2.299 ± 1.235
3.448SerPhe: 3.448 ± 1.312
2.299SerGly: 2.299 ± 1.235
0.0SerHis: 0.0 ± 0.0
3.448SerIle: 3.448 ± 1.911
1.149SerLys: 1.149 ± 0.618
8.046SerLeu: 8.046 ± 2.815
1.149SerMet: 1.149 ± 0.618
3.448SerAsn: 3.448 ± 1.853
5.747SerPro: 5.747 ± 4.44
4.598SerGln: 4.598 ± 1.41
4.598SerArg: 4.598 ± 1.294
10.345SerSer: 10.345 ± 4.095
6.897SerThr: 6.897 ± 0.081
3.448SerVal: 3.448 ± 1.312
3.448SerTrp: 3.448 ± 4.054
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
1.149ThrAla: 1.149 ± 0.618
1.149ThrCys: 1.149 ± 1.864
3.448ThrAsp: 3.448 ± 3.26
10.345ThrGlu: 10.345 ± 1.796
3.448ThrPhe: 3.448 ± 1.853
5.747ThrGly: 5.747 ± 1.864
1.149ThrHis: 1.149 ± 0.618
4.598ThrIle: 4.598 ± 1.41
1.149ThrLys: 1.149 ± 0.618
3.448ThrLeu: 3.448 ± 1.853
1.149ThrMet: 1.149 ± 0.618
2.299ThrAsn: 2.299 ± 1.235
3.448ThrPro: 3.448 ± 3.317
2.299ThrGln: 2.299 ± 1.235
2.299ThrArg: 2.299 ± 1.235
2.299ThrSer: 2.299 ± 1.484
3.448ThrThr: 3.448 ± 1.312
8.046ThrVal: 8.046 ± 4.207
1.149ThrTrp: 1.149 ± 0.618
3.448ThrTyr: 3.448 ± 1.365
0.0ThrXaa: 0.0 ± 0.0
Val
3.448ValAla: 3.448 ± 1.853
1.149ValCys: 1.149 ± 0.618
0.0ValAsp: 0.0 ± 0.0
4.598ValGlu: 4.598 ± 5.172
0.0ValPhe: 0.0 ± 0.0
1.149ValGly: 1.149 ± 0.618
3.448ValHis: 3.448 ± 1.853
1.149ValIle: 1.149 ± 0.618
0.0ValLys: 0.0 ± 0.0
4.598ValLeu: 4.598 ± 5.172
2.299ValMet: 2.299 ± 1.235
1.149ValAsn: 1.149 ± 0.618
3.448ValPro: 3.448 ± 1.312
1.149ValGln: 1.149 ± 0.618
1.149ValArg: 1.149 ± 0.618
3.448ValSer: 3.448 ± 1.312
1.149ValThr: 1.149 ± 0.618
2.299ValVal: 2.299 ± 3.729
1.149ValTrp: 1.149 ± 0.618
1.149ValTyr: 1.149 ± 0.618
0.0ValXaa: 0.0 ± 0.0
Trp
2.299TrpAla: 2.299 ± 1.235
1.149TrpCys: 1.149 ± 0.618
0.0TrpAsp: 0.0 ± 0.0
2.299TrpGlu: 2.299 ± 1.484
1.149TrpPhe: 1.149 ± 1.817
3.448TrpGly: 3.448 ± 1.853
1.149TrpHis: 1.149 ± 0.618
1.149TrpIle: 1.149 ± 1.864
0.0TrpLys: 0.0 ± 0.0
3.448TrpLeu: 3.448 ± 1.911
1.149TrpMet: 1.149 ± 1.864
2.299TrpAsn: 2.299 ± 1.235
4.598TrpPro: 4.598 ± 1.294
0.0TrpGln: 0.0 ± 0.0
5.747TrpArg: 5.747 ± 3.088
1.149TrpSer: 1.149 ± 0.618
1.149TrpThr: 1.149 ± 0.618
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
3.448TrpTyr: 3.448 ± 1.853
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.149TyrAla: 1.149 ± 1.817
1.149TyrCys: 1.149 ± 0.618
3.448TyrAsp: 3.448 ± 1.365
0.0TyrGlu: 0.0 ± 0.0
2.299TyrPhe: 2.299 ± 1.235
3.448TyrGly: 3.448 ± 1.853
1.149TyrHis: 1.149 ± 1.864
1.149TyrIle: 1.149 ± 0.618
1.149TyrLys: 1.149 ± 0.618
0.0TyrLeu: 0.0 ± 0.0
1.149TyrMet: 1.149 ± 0.618
1.149TyrAsn: 1.149 ± 0.618
2.299TyrPro: 2.299 ± 1.235
1.149TyrGln: 1.149 ± 0.618
3.448TyrArg: 3.448 ± 1.853
3.448TyrSer: 3.448 ± 1.853
1.149TyrThr: 1.149 ± 0.618
0.0TyrVal: 0.0 ± 0.0
1.149TyrTrp: 1.149 ± 0.618
2.299TyrTyr: 2.299 ± 1.235
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (871 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski