Amino acid dipepetide frequency for Sandaracinus amylolyticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.783AlaAla: 16.783 ± 0.127	2.235AlaCys: 2.235 ± 0.054	6.578AlaAsp: 6.578 ± 0.055	7.642AlaGlu: 7.642 ± 0.063	3.711AlaPhe: 3.711 ± 0.035	10.503AlaGly: 10.503 ± 0.073	3.116AlaHis: 3.116 ± 0.037	7.015AlaIle: 7.015 ± 0.059	2.446AlaLys: 2.446 ± 0.042	16.392AlaLeu: 16.392 ± 0.137	3.196AlaMet: 3.196 ± 0.039	1.816AlaAsn: 1.816 ± 0.029	8.699AlaPro: 8.699 ± 0.071	3.842AlaGln: 3.842 ± 0.04	15.391AlaArg: 15.391 ± 0.118	8.955AlaSer: 8.955 ± 0.063	7.49AlaThr: 7.49 ± 0.057	8.398AlaVal: 8.398 ± 0.051	2.162AlaTrp: 2.162 ± 0.032	2.209AlaTyr: 2.209 ± 0.031	0.0AlaXaa: 0.0 ± 0.0
Cys	1.955CysAla: 1.955 ± 0.045	0.187CysCys: 0.187 ± 0.012	1.316CysAsp: 1.316 ± 0.046	0.937CysGlu: 0.937 ± 0.022	0.316CysPhe: 0.316 ± 0.011	1.702CysGly: 1.702 ± 0.057	0.265CysHis: 0.265 ± 0.011	0.346CysIle: 0.346 ± 0.011	0.091CysLys: 0.091 ± 0.006	0.723CysLeu: 0.723 ± 0.017	0.161CysMet: 0.161 ± 0.007	0.339CysAsn: 0.339 ± 0.02	0.68CysPro: 0.68 ± 0.022	0.226CysGln: 0.226 ± 0.01	0.867CysArg: 0.867 ± 0.022	0.783CysSer: 0.783 ± 0.026	0.887CysThr: 0.887 ± 0.034	1.163CysVal: 1.163 ± 0.029	0.19CysTrp: 0.19 ± 0.013	0.181CysTyr: 0.181 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	11.534AspAla: 11.534 ± 0.083	0.886AspCys: 0.886 ± 0.041	5.336AspAsp: 5.336 ± 0.076	4.978AspGlu: 4.978 ± 0.047	1.575AspPhe: 1.575 ± 0.026	6.854AspGly: 6.854 ± 0.082	1.323AspHis: 1.323 ± 0.023	1.243AspIle: 1.243 ± 0.024	0.56AspLys: 0.56 ± 0.017	5.721AspLeu: 5.721 ± 0.05	0.699AspMet: 0.699 ± 0.014	0.63AspAsn: 0.63 ± 0.02	4.533AspPro: 4.533 ± 0.043	1.19AspGln: 1.19 ± 0.022	5.56AspArg: 5.56 ± 0.05	1.788AspSer: 1.788 ± 0.026	2.336AspThr: 2.336 ± 0.032	6.459AspVal: 6.459 ± 0.052	0.703AspTrp: 0.703 ± 0.015	0.91AspTyr: 0.91 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	7.643GluAla: 7.643 ± 0.065	0.772GluCys: 0.772 ± 0.026	3.34GluAsp: 3.34 ± 0.038	3.568GluGlu: 3.568 ± 0.047	1.03GluPhe: 1.03 ± 0.02	5.69GluGly: 5.69 ± 0.046	1.917GluHis: 1.917 ± 0.027	3.155GluIle: 3.155 ± 0.037	1.152GluLys: 1.152 ± 0.029	7.719GluLeu: 7.719 ± 0.058	1.294GluMet: 1.294 ± 0.019	0.921GluAsn: 0.921 ± 0.016	3.92GluPro: 3.92 ± 0.045	2.127GluGln: 2.127 ± 0.034	7.994GluArg: 7.994 ± 0.072	3.274GluSer: 3.274 ± 0.03	3.28GluThr: 3.28 ± 0.036	4.901GluVal: 4.901 ± 0.048	0.809GluTrp: 0.809 ± 0.015	0.911GluTyr: 0.911 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.83PheAla: 3.83 ± 0.034	0.332PheCys: 0.332 ± 0.012	2.372PheAsp: 2.372 ± 0.032	2.194PheGlu: 2.194 ± 0.029	1.082PhePhe: 1.082 ± 0.021	2.829PheGly: 2.829 ± 0.035	0.649PheHis: 0.649 ± 0.015	0.532PheIle: 0.532 ± 0.015	0.316PheLys: 0.316 ± 0.012	2.457PheLeu: 2.457 ± 0.031	0.395PheMet: 0.395 ± 0.013	0.392PheAsn: 0.392 ± 0.011	1.238PhePro: 1.238 ± 0.021	0.647PheGln: 0.647 ± 0.014	2.066PheArg: 2.066 ± 0.031	1.324PheSer: 1.324 ± 0.023	1.482PheThr: 1.482 ± 0.024	3.202PheVal: 3.202 ± 0.035	0.344PheTrp: 0.344 ± 0.011	0.586PheTyr: 0.586 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	12.603GlyAla: 12.603 ± 0.081	1.441GlyCys: 1.441 ± 0.03	5.867GlyAsp: 5.867 ± 0.066	5.985GlyGlu: 5.985 ± 0.044	2.643GlyPhe: 2.643 ± 0.035	8.747GlyGly: 8.747 ± 0.109	1.787GlyHis: 1.787 ± 0.026	3.369GlyIle: 3.369 ± 0.035	1.463GlyLys: 1.463 ± 0.031	7.072GlyLeu: 7.072 ± 0.054	1.766GlyMet: 1.766 ± 0.025	1.437GlyAsn: 1.437 ± 0.026	4.035GlyPro: 4.035 ± 0.039	1.87GlyGln: 1.87 ± 0.034	7.3GlyArg: 7.3 ± 0.054	4.894GlySer: 4.894 ± 0.055	5.622GlyThr: 5.622 ± 0.074	6.972GlyVal: 6.972 ± 0.06	1.357GlyTrp: 1.357 ± 0.026	1.7GlyTyr: 1.7 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	3.377HisAla: 3.377 ± 0.035	0.267HisCys: 0.267 ± 0.011	1.647HisAsp: 1.647 ± 0.025	1.539HisGlu: 1.539 ± 0.026	0.656HisPhe: 0.656 ± 0.016	2.133HisGly: 2.133 ± 0.028	0.625HisHis: 0.625 ± 0.016	0.4HisIle: 0.4 ± 0.011	0.222HisLys: 0.222 ± 0.009	2.017HisLeu: 2.017 ± 0.023	0.254HisMet: 0.254 ± 0.01	0.259HisAsn: 0.259 ± 0.01	1.44HisPro: 1.44 ± 0.022	0.443HisGln: 0.443 ± 0.011	2.021HisArg: 2.021 ± 0.029	0.679HisSer: 0.679 ± 0.016	0.877HisThr: 0.877 ± 0.018	2.353HisVal: 2.353 ± 0.033	0.274HisTrp: 0.274 ± 0.01	0.423HisTyr: 0.423 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	7.541IleAla: 7.541 ± 0.06	0.349IleCys: 0.349 ± 0.011	3.763IleAsp: 3.763 ± 0.039	3.646IleGlu: 3.646 ± 0.041	0.84IlePhe: 0.84 ± 0.017	3.731IleGly: 3.731 ± 0.038	0.721IleHis: 0.721 ± 0.016	0.698IleIle: 0.698 ± 0.019	0.467IleLys: 0.467 ± 0.014	2.434IleLeu: 2.434 ± 0.034	0.327IleMet: 0.327 ± 0.012	0.46IleAsn: 0.46 ± 0.014	1.867IlePro: 1.867 ± 0.024	0.744IleGln: 0.744 ± 0.016	2.391IleArg: 2.391 ± 0.029	1.585IleSer: 1.585 ± 0.023	2.285IleThr: 2.285 ± 0.028	4.143IleVal: 4.143 ± 0.041	0.334IleTrp: 0.334 ± 0.011	0.567IleTyr: 0.567 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	1.579LysAla: 1.579 ± 0.034	0.087LysCys: 0.087 ± 0.005	0.775LysAsp: 0.775 ± 0.022	0.8LysGlu: 0.8 ± 0.024	0.293LysPhe: 0.293 ± 0.011	1.14LysGly: 1.14 ± 0.024	0.412LysHis: 0.412 ± 0.011	0.69LysIle: 0.69 ± 0.017	0.851LysLys: 0.851 ± 0.027	1.744LysLeu: 1.744 ± 0.034	0.317LysMet: 0.317 ± 0.011	0.352LysAsn: 0.352 ± 0.012	0.931LysPro: 0.931 ± 0.02	0.484LysGln: 0.484 ± 0.013	1.568LysArg: 1.568 ± 0.028	0.817LysSer: 0.817 ± 0.018	0.874LysThr: 0.874 ± 0.02	1.213LysVal: 1.213 ± 0.025	0.177LysTrp: 0.177 ± 0.007	0.283LysTyr: 0.283 ± 0.01	0.0LysXaa: 0.0 ± 0.0
Leu	15.668LeuAla: 15.668 ± 0.121	0.969LeuCys: 0.969 ± 0.021	6.989LeuAsp: 6.989 ± 0.058	6.879LeuGlu: 6.879 ± 0.067	2.816LeuPhe: 2.816 ± 0.037	8.914LeuGly: 8.914 ± 0.059	2.062LeuHis: 2.062 ± 0.029	2.568LeuIle: 2.568 ± 0.03	1.225LeuLys: 1.225 ± 0.027	8.502LeuLeu: 8.502 ± 0.073	1.335LeuMet: 1.335 ± 0.021	1.036LeuAsn: 1.036 ± 0.02	5.059LeuPro: 5.059 ± 0.043	1.912LeuGln: 1.912 ± 0.028	9.276LeuArg: 9.276 ± 0.069	4.77LeuSer: 4.77 ± 0.043	4.249LeuThr: 4.249 ± 0.036	9.11LeuVal: 9.11 ± 0.069	1.049LeuTrp: 1.049 ± 0.021	1.648LeuTyr: 1.648 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.789MetAla: 1.789 ± 0.029	0.188MetCys: 0.188 ± 0.008	0.808MetAsp: 0.808 ± 0.014	0.862MetGlu: 0.862 ± 0.017	0.434MetPhe: 0.434 ± 0.012	1.358MetGly: 1.358 ± 0.024	0.456MetHis: 0.456 ± 0.014	0.9MetIle: 0.9 ± 0.016	0.446MetLys: 0.446 ± 0.013	2.094MetLeu: 2.094 ± 0.028	0.405MetMet: 0.405 ± 0.013	0.372MetAsn: 0.372 ± 0.01	1.304MetPro: 1.304 ± 0.022	0.61MetGln: 0.61 ± 0.015	2.264MetArg: 2.264 ± 0.029	1.308MetSer: 1.308 ± 0.025	1.166MetThr: 1.166 ± 0.021	1.26MetVal: 1.26 ± 0.022	0.186MetTrp: 0.186 ± 0.008	0.213MetTyr: 0.213 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	1.96AsnAla: 1.96 ± 0.024	0.192AsnCys: 0.192 ± 0.014	1.049AsnAsp: 1.049 ± 0.024	0.887AsnGlu: 0.887 ± 0.016	0.369AsnPhe: 0.369 ± 0.011	1.568AsnGly: 1.568 ± 0.029	0.3AsnHis: 0.3 ± 0.01	0.41AsnIle: 0.41 ± 0.014	0.206AsnLys: 0.206 ± 0.009	1.297AsnLeu: 1.297 ± 0.022	0.195AsnMet: 0.195 ± 0.007	0.268AsnAsn: 0.268 ± 0.012	0.91AsnPro: 0.91 ± 0.019	0.33AsnGln: 0.33 ± 0.011	1.001AsnArg: 1.001 ± 0.017	0.468AsnSer: 0.468 ± 0.013	0.672AsnThr: 0.672 ± 0.02	1.611AsnVal: 1.611 ± 0.024	0.163AsnTrp: 0.163 ± 0.007	0.281AsnTyr: 0.281 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	7.092ProAla: 7.092 ± 0.06	0.555ProCys: 0.555 ± 0.018	4.005ProAsp: 4.005 ± 0.042	4.395ProGlu: 4.395 ± 0.041	1.769ProPhe: 1.769 ± 0.024	5.068ProGly: 5.068 ± 0.047	1.161ProHis: 1.161 ± 0.02	2.469ProIle: 2.469 ± 0.03	0.868ProLys: 0.868 ± 0.021	4.787ProLeu: 4.787 ± 0.045	1.181ProMet: 1.181 ± 0.019	0.869ProAsn: 0.869 ± 0.02	4.42ProPro: 4.42 ± 0.073	1.241ProGln: 1.241 ± 0.021	5.073ProArg: 5.073 ± 0.051	4.014ProSer: 4.014 ± 0.043	3.226ProThr: 3.226 ± 0.035	4.006ProVal: 4.006 ± 0.037	0.806ProTrp: 0.806 ± 0.015	0.958ProTyr: 0.958 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	2.553GlnAla: 2.553 ± 0.033	0.321GlnCys: 0.321 ± 0.012	1.094GlnAsp: 1.094 ± 0.02	1.109GlnGlu: 1.109 ± 0.022	0.566GlnPhe: 0.566 ± 0.014	1.793GlnGly: 1.793 ± 0.029	0.636GlnHis: 0.636 ± 0.015	1.116GlnIle: 1.116 ± 0.02	0.445GlnLys: 0.445 ± 0.014	2.704GlnLeu: 2.704 ± 0.028	0.481GlnMet: 0.481 ± 0.013	0.385GlnAsn: 0.385 ± 0.011	1.404GlnPro: 1.404 ± 0.022	0.855GlnGln: 0.855 ± 0.028	2.792GlnArg: 2.792 ± 0.032	1.285GlnSer: 1.285 ± 0.022	1.134GlnThr: 1.134 ± 0.022	1.859GlnVal: 1.859 ± 0.027	0.36GlnTrp: 0.36 ± 0.011	0.442GlnTyr: 0.442 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	15.213ArgAla: 15.213 ± 0.117	1.177ArgCys: 1.177 ± 0.03	6.345ArgAsp: 6.345 ± 0.049	6.693ArgGlu: 6.693 ± 0.058	3.266ArgPhe: 3.266 ± 0.036	7.413ArgGly: 7.413 ± 0.057	1.785ArgHis: 1.785 ± 0.025	4.126ArgIle: 4.126 ± 0.037	1.283ArgLys: 1.283 ± 0.025	7.976ArgLeu: 7.976 ± 0.063	2.118ArgMet: 2.118 ± 0.028	1.195ArgAsn: 1.195 ± 0.02	4.376ArgPro: 4.376 ± 0.041	1.602ArgGln: 1.602 ± 0.024	8.64ArgArg: 8.64 ± 0.067	4.648ArgSer: 4.648 ± 0.041	4.797ArgThr: 4.797 ± 0.04	8.52ArgVal: 8.52 ± 0.066	1.595ArgTrp: 1.595 ± 0.023	1.782ArgTyr: 1.782 ± 0.028	0.0ArgXaa: 0.0 ± 0.0
Ser	7.106SerAla: 7.106 ± 0.053	0.88SerCys: 0.88 ± 0.025	3.302SerAsp: 3.302 ± 0.038	3.221SerGlu: 3.221 ± 0.033	1.782SerPhe: 1.782 ± 0.027	5.337SerGly: 5.337 ± 0.058	0.987SerHis: 0.987 ± 0.018	2.392SerIle: 2.392 ± 0.028	0.797SerLys: 0.797 ± 0.018	4.877SerLeu: 4.877 ± 0.038	1.187SerMet: 1.187 ± 0.02	0.808SerAsn: 0.808 ± 0.018	3.096SerPro: 3.096 ± 0.032	1.126SerGln: 1.126 ± 0.022	4.418SerArg: 4.418 ± 0.04	3.521SerSer: 3.521 ± 0.046	3.136SerThr: 3.136 ± 0.039	3.857SerVal: 3.857 ± 0.037	0.785SerTrp: 0.785 ± 0.018	0.983SerTyr: 0.983 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.505ThrAla: 5.505 ± 0.052	1.004ThrCys: 1.004 ± 0.037	2.715ThrAsp: 2.715 ± 0.04	2.62ThrGlu: 2.62 ± 0.033	1.855ThrPhe: 1.855 ± 0.028	4.461ThrGly: 4.461 ± 0.052	1.101ThrHis: 1.101 ± 0.021	2.734ThrIle: 2.734 ± 0.031	0.929ThrLys: 0.929 ± 0.019	5.474ThrLeu: 5.474 ± 0.048	1.056ThrMet: 1.056 ± 0.021	0.941ThrAsn: 0.941 ± 0.018	3.803ThrPro: 3.803 ± 0.041	1.24ThrGln: 1.24 ± 0.021	4.709ThrArg: 4.709 ± 0.04	3.482ThrSer: 3.482 ± 0.039	3.71ThrThr: 3.71 ± 0.051	3.68ThrVal: 3.68 ± 0.042	0.892ThrTrp: 0.892 ± 0.018	1.057ThrTyr: 1.057 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	11.2ValAla: 11.2 ± 0.072	1.073ValCys: 1.073 ± 0.034	5.459ValAsp: 5.459 ± 0.046	5.527ValGlu: 5.527 ± 0.05	2.226ValPhe: 2.226 ± 0.026	6.147ValGly: 6.147 ± 0.053	1.95ValHis: 1.95 ± 0.025	3.631ValIle: 3.631 ± 0.036	1.18ValLys: 1.18 ± 0.026	8.809ValLeu: 8.809 ± 0.07	1.454ValMet: 1.454 ± 0.021	1.071ValAsn: 1.071 ± 0.021	4.777ValPro: 4.777 ± 0.043	2.003ValGln: 2.003 ± 0.023	8.216ValArg: 8.216 ± 0.065	4.234ValSer: 4.234 ± 0.042	4.143ValThr: 4.143 ± 0.047	8.154ValVal: 8.154 ± 0.069	1.004ValTrp: 1.004 ± 0.019	1.357ValTyr: 1.357 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.411TrpAla: 1.411 ± 0.021	0.174TrpCys: 0.174 ± 0.009	0.791TrpAsp: 0.791 ± 0.017	0.66TrpGlu: 0.66 ± 0.017	0.375TrpPhe: 0.375 ± 0.011	0.98TrpGly: 0.98 ± 0.023	0.301TrpHis: 0.301 ± 0.009	0.817TrpIle: 0.817 ± 0.017	0.24TrpLys: 0.24 ± 0.01	1.558TrpLeu: 1.558 ± 0.028	0.368TrpMet: 0.368 ± 0.013	0.318TrpAsn: 0.318 ± 0.01	0.664TrpPro: 0.664 ± 0.017	0.369TrpGln: 0.369 ± 0.014	1.292TrpArg: 1.292 ± 0.02	1.055TrpSer: 1.055 ± 0.018	0.848TrpThr: 0.848 ± 0.019	0.964TrpVal: 0.964 ± 0.019	0.248TrpTrp: 0.248 ± 0.009	0.255TrpTyr: 0.255 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.237TyrAla: 2.237 ± 0.029	0.225TyrCys: 0.225 ± 0.01	1.267TyrAsp: 1.267 ± 0.025	1.276TyrGlu: 1.276 ± 0.022	0.666TyrPhe: 0.666 ± 0.014	1.56TyrGly: 1.56 ± 0.027	0.354TyrHis: 0.354 ± 0.01	0.284TyrIle: 0.284 ± 0.009	0.2TyrLys: 0.2 ± 0.009	1.678TyrLeu: 1.678 ± 0.024	0.237TyrMet: 0.237 ± 0.009	0.268TyrAsn: 0.268 ± 0.009	0.809TyrPro: 0.809 ± 0.018	0.472TyrGln: 0.472 ± 0.014	1.707TyrArg: 1.707 ± 0.025	0.714TyrSer: 0.714 ± 0.017	0.753TyrThr: 0.753 ± 0.015	1.786TyrVal: 1.786 ± 0.029	0.251TyrTrp: 0.251 ± 0.01	0.437TyrTyr: 0.437 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8941 proteins (3139928 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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