Amino acid dipepetide frequency for Bamboo mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.809AlaAla: 8.809 ± 2.632
0.464AlaCys: 0.464 ± 0.685
3.245AlaAsp: 3.245 ± 1.092
1.854AlaGlu: 1.854 ± 0.993
4.636AlaPhe: 4.636 ± 1.373
5.563AlaGly: 5.563 ± 1.981
2.318AlaHis: 2.318 ± 1.047
5.1AlaIle: 5.1 ± 1.749
6.49AlaLys: 6.49 ± 1.027
8.809AlaLeu: 8.809 ± 1.134
0.927AlaMet: 0.927 ± 0.496
6.49AlaAsn: 6.49 ± 3.126
5.1AlaPro: 5.1 ± 2.854
1.854AlaGln: 1.854 ± 0.993
4.636AlaArg: 4.636 ± 0.502
5.563AlaSer: 5.563 ± 1.705
6.027AlaThr: 6.027 ± 1.141
1.391AlaVal: 1.391 ± 0.52
0.927AlaTrp: 0.927 ± 0.555
3.709AlaTyr: 3.709 ± 1.475
0.0AlaXaa: 0.0 ± 0.0
Cys
1.391CysAla: 1.391 ± 0.558
0.0CysCys: 0.0 ± 0.0
0.464CysAsp: 0.464 ± 0.685
1.391CysGlu: 1.391 ± 1.002
0.0CysPhe: 0.0 ± 0.0
0.464CysGly: 0.464 ± 0.248
1.391CysHis: 1.391 ± 1.649
0.927CysIle: 0.927 ± 1.056
1.391CysLys: 1.391 ± 0.745
1.854CysLeu: 1.854 ± 0.821
0.464CysMet: 0.464 ± 0.694
0.927CysAsn: 0.927 ± 0.496
2.782CysPro: 2.782 ± 0.793
0.464CysGln: 0.464 ± 0.248
0.0CysArg: 0.0 ± 0.0
0.927CysSer: 0.927 ± 0.899
0.464CysThr: 0.464 ± 0.248
0.464CysVal: 0.464 ± 1.025
0.0CysTrp: 0.0 ± 0.0
0.464CysTyr: 0.464 ± 1.161
0.0CysXaa: 0.0 ± 0.0
Asp
3.709AspAla: 3.709 ± 1.601
0.464AspCys: 0.464 ± 0.248
1.391AspAsp: 1.391 ± 0.558
3.245AspGlu: 3.245 ± 1.163
1.854AspPhe: 1.854 ± 0.993
2.782AspGly: 2.782 ± 1.381
0.0AspHis: 0.0 ± 0.0
1.854AspIle: 1.854 ± 0.993
0.464AspLys: 0.464 ± 0.685
6.027AspLeu: 6.027 ± 2.054
0.927AspMet: 0.927 ± 0.675
3.245AspAsn: 3.245 ± 1.692
3.709AspPro: 3.709 ± 0.905
3.709AspGln: 3.709 ± 1.562
2.318AspArg: 2.318 ± 1.051
2.318AspSer: 2.318 ± 0.905
4.172AspThr: 4.172 ± 1.088
3.709AspVal: 3.709 ± 1.389
0.464AspTrp: 0.464 ± 0.248
0.927AspTyr: 0.927 ± 0.496
0.0AspXaa: 0.0 ± 0.0
Glu
5.563GluAla: 5.563 ± 1.515
0.927GluCys: 0.927 ± 0.496
1.854GluAsp: 1.854 ± 0.993
2.782GluGlu: 2.782 ± 0.947
1.854GluPhe: 1.854 ± 0.597
2.318GluGly: 2.318 ± 0.873
2.318GluHis: 2.318 ± 0.873
4.172GluIle: 4.172 ± 0.837
2.782GluLys: 2.782 ± 1.489
5.1GluLeu: 5.1 ± 2.251
0.0GluMet: 0.0 ± 0.0
2.318GluAsn: 2.318 ± 1.241
6.954GluPro: 6.954 ± 1.611
0.464GluGln: 0.464 ± 0.248
2.782GluArg: 2.782 ± 1.489
3.245GluSer: 3.245 ± 1.738
3.709GluThr: 3.709 ± 1.536
2.318GluVal: 2.318 ± 1.241
0.464GluTrp: 0.464 ± 0.248
1.854GluTyr: 1.854 ± 1.111
0.0GluXaa: 0.0 ± 0.0
Phe
1.854PheAla: 1.854 ± 1.043
1.391PheCys: 1.391 ± 0.745
3.709PheAsp: 3.709 ± 1.403
2.782PheGlu: 2.782 ± 1.489
0.0PhePhe: 0.0 ± 0.0
1.854PheGly: 1.854 ± 0.832
0.927PheHis: 0.927 ± 0.496
1.854PheIle: 1.854 ± 1.008
1.391PheLys: 1.391 ± 0.558
3.245PheLeu: 3.245 ± 1.277
1.854PheMet: 1.854 ± 0.689
0.464PheAsn: 0.464 ± 0.596
0.0PhePro: 0.0 ± 0.0
1.854PheGln: 1.854 ± 0.597
0.927PheArg: 0.927 ± 0.496
3.709PheSer: 3.709 ± 0.811
3.245PheThr: 3.245 ± 0.907
0.0PheVal: 0.0 ± 0.0
0.927PheTrp: 0.927 ± 0.496
0.927PheTyr: 0.927 ± 0.496
0.0PheXaa: 0.0 ± 0.0
Gly
3.245GlyAla: 3.245 ± 1.289
0.464GlyCys: 0.464 ± 0.248
4.636GlyAsp: 4.636 ± 1.939
2.318GlyGlu: 2.318 ± 1.241
1.391GlyPhe: 1.391 ± 0.708
4.636GlyGly: 4.636 ± 3.481
1.391GlyHis: 1.391 ± 1.002
3.709GlyIle: 3.709 ± 1.064
2.782GlyLys: 2.782 ± 0.947
4.636GlyLeu: 4.636 ± 2.659
0.0GlyMet: 0.0 ± 0.0
1.854GlyAsn: 1.854 ± 1.008
4.636GlyPro: 4.636 ± 2.316
2.782GlyGln: 2.782 ± 2.612
3.245GlyArg: 3.245 ± 1.29
2.318GlySer: 2.318 ± 1.774
6.954GlyThr: 6.954 ± 5.109
2.318GlyVal: 2.318 ± 1.558
0.0GlyTrp: 0.0 ± 0.0
1.854GlyTyr: 1.854 ± 1.111
0.0GlyXaa: 0.0 ± 0.0
His
1.391HisAla: 1.391 ± 0.52
0.927HisCys: 0.927 ± 1.309
2.782HisAsp: 2.782 ± 1.489
0.464HisGlu: 0.464 ± 0.248
0.927HisPhe: 0.927 ± 0.496
2.318HisGly: 2.318 ± 1.944
1.391HisHis: 1.391 ± 1.13
3.245HisIle: 3.245 ± 1.163
1.391HisLys: 1.391 ± 0.558
2.318HisLeu: 2.318 ± 1.586
0.464HisMet: 0.464 ± 0.248
0.927HisAsn: 0.927 ± 0.555
0.927HisPro: 0.927 ± 0.611
1.391HisGln: 1.391 ± 0.83
2.318HisArg: 2.318 ± 1.636
1.854HisSer: 1.854 ± 0.993
4.636HisThr: 4.636 ± 2.609
0.464HisVal: 0.464 ± 0.248
0.927HisTrp: 0.927 ± 0.496
1.854HisTyr: 1.854 ± 0.597
0.0HisXaa: 0.0 ± 0.0
Ile
4.636IleAla: 4.636 ± 0.958
0.0IleCys: 0.0 ± 0.0
1.854IleAsp: 1.854 ± 0.689
3.245IleGlu: 3.245 ± 1.305
2.782IlePhe: 2.782 ± 1.489
2.318IleGly: 2.318 ± 0.848
2.782IleHis: 2.782 ± 0.809
2.782IleIle: 2.782 ± 3.304
4.172IleLys: 4.172 ± 1.559
8.345IleLeu: 8.345 ± 5.0
0.927IleMet: 0.927 ± 0.496
3.245IleAsn: 3.245 ± 0.927
1.854IlePro: 1.854 ± 0.597
2.318IleGln: 2.318 ± 1.051
3.709IleArg: 3.709 ± 0.829
2.318IleSer: 2.318 ± 1.176
6.027IleThr: 6.027 ± 0.626
1.854IleVal: 1.854 ± 0.993
0.0IleTrp: 0.0 ± 0.0
2.782IleTyr: 2.782 ± 0.724
0.0IleXaa: 0.0 ± 0.0
Lys
6.954LysAla: 6.954 ± 1.702
3.245LysCys: 3.245 ± 1.201
3.709LysAsp: 3.709 ± 0.905
2.318LysGlu: 2.318 ± 0.873
2.318LysPhe: 2.318 ± 0.873
2.318LysGly: 2.318 ± 0.952
1.854LysHis: 1.854 ± 0.597
3.245LysIle: 3.245 ± 1.305
2.318LysLys: 2.318 ± 0.997
5.1LysLeu: 5.1 ± 2.041
1.391LysMet: 1.391 ± 0.745
2.782LysAsn: 2.782 ± 1.117
5.563LysPro: 5.563 ± 1.441
4.172LysGln: 4.172 ± 1.097
3.245LysArg: 3.245 ± 2.606
2.318LysSer: 2.318 ± 1.241
5.1LysThr: 5.1 ± 1.191
2.782LysVal: 2.782 ± 1.294
1.391LysTrp: 1.391 ± 0.708
1.854LysTyr: 1.854 ± 0.597
0.0LysXaa: 0.0 ± 0.0
Leu
6.954LeuAla: 6.954 ± 2.423
0.927LeuCys: 0.927 ± 1.409
3.709LeuAsp: 3.709 ± 1.37
4.636LeuGlu: 4.636 ± 1.041
4.172LeuPhe: 4.172 ± 1.292
5.563LeuGly: 5.563 ± 0.896
3.709LeuHis: 3.709 ± 1.386
5.563LeuIle: 5.563 ± 0.817
6.027LeuLys: 6.027 ± 2.504
6.954LeuLeu: 6.954 ± 1.997
0.0LeuMet: 0.0 ± 0.0
5.563LeuAsn: 5.563 ± 2.59
13.908LeuPro: 13.908 ± 1.99
5.563LeuGln: 5.563 ± 1.444
5.563LeuArg: 5.563 ± 1.337
2.318LeuSer: 2.318 ± 0.733
5.563LeuThr: 5.563 ± 1.697
3.709LeuVal: 3.709 ± 0.962
0.927LeuTrp: 0.927 ± 0.496
6.027LeuTyr: 6.027 ± 1.114
0.0LeuXaa: 0.0 ± 0.0
Met
1.854MetAla: 1.854 ± 0.689
0.927MetCys: 0.927 ± 0.496
1.391MetAsp: 1.391 ± 0.92
0.0MetGlu: 0.0 ± 0.0
0.464MetPhe: 0.464 ± 0.248
0.464MetGly: 0.464 ± 0.248
0.0MetHis: 0.0 ± 0.0
0.927MetIle: 0.927 ± 0.496
1.391MetLys: 1.391 ± 0.558
1.854MetLeu: 1.854 ± 1.059
0.0MetMet: 0.0 ± 0.0
0.464MetAsn: 0.464 ± 0.248
1.391MetPro: 1.391 ± 0.83
0.927MetGln: 0.927 ± 0.496
1.391MetArg: 1.391 ± 0.745
0.927MetSer: 0.927 ± 0.521
0.927MetThr: 0.927 ± 0.496
0.464MetVal: 0.464 ± 0.71
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.636AsnAla: 4.636 ± 1.466
2.782AsnCys: 2.782 ± 1.604
2.318AsnAsp: 2.318 ± 0.873
1.854AsnGlu: 1.854 ± 0.993
0.927AsnPhe: 0.927 ± 1.192
0.927AsnGly: 0.927 ± 1.056
2.318AsnHis: 2.318 ± 0.848
3.245AsnIle: 3.245 ± 1.376
1.854AsnLys: 1.854 ± 0.832
3.245AsnLeu: 3.245 ± 1.967
0.0AsnMet: 0.0 ± 0.0
1.391AsnAsn: 1.391 ± 0.83
3.709AsnPro: 3.709 ± 1.953
0.927AsnGln: 0.927 ± 0.496
0.927AsnArg: 0.927 ± 0.555
2.318AsnSer: 2.318 ± 0.881
4.636AsnThr: 4.636 ± 1.409
2.782AsnVal: 2.782 ± 1.564
0.927AsnTrp: 0.927 ± 0.496
2.782AsnTyr: 2.782 ± 0.793
0.0AsnXaa: 0.0 ± 0.0
Pro
6.027ProAla: 6.027 ± 1.903
1.854ProCys: 1.854 ± 1.458
3.245ProAsp: 3.245 ± 1.163
6.954ProGlu: 6.954 ± 2.538
1.391ProPhe: 1.391 ± 1.13
1.391ProGly: 1.391 ± 1.223
2.782ProHis: 2.782 ± 2.69
3.709ProIle: 3.709 ± 0.887
6.954ProLys: 6.954 ± 1.702
7.418ProLeu: 7.418 ± 1.836
0.464ProMet: 0.464 ± 0.248
2.318ProAsn: 2.318 ± 2.178
3.709ProPro: 3.709 ± 2.713
3.245ProGln: 3.245 ± 1.761
4.636ProArg: 4.636 ± 1.552
4.172ProSer: 4.172 ± 1.318
8.809ProThr: 8.809 ± 3.055
2.318ProVal: 2.318 ± 0.905
0.927ProTrp: 0.927 ± 0.521
1.854ProTyr: 1.854 ± 0.689
0.0ProXaa: 0.0 ± 0.0
Gln
3.245GlnAla: 3.245 ± 1.481
0.0GlnCys: 0.0 ± 0.0
1.391GlnAsp: 1.391 ± 0.52
3.709GlnGlu: 3.709 ± 1.389
1.391GlnPhe: 1.391 ± 0.745
3.245GlnGly: 3.245 ± 0.856
1.854GlnHis: 1.854 ± 1.653
0.927GlnIle: 0.927 ± 0.521
1.854GlnLys: 1.854 ± 0.689
3.709GlnLeu: 3.709 ± 1.157
0.0GlnMet: 0.0 ± 0.0
2.318GlnAsn: 2.318 ± 2.807
3.245GlnPro: 3.245 ± 1.088
3.709GlnGln: 3.709 ± 1.97
0.464GlnArg: 0.464 ± 0.248
3.709GlnSer: 3.709 ± 0.905
6.027GlnThr: 6.027 ± 3.956
1.854GlnVal: 1.854 ± 0.993
0.927GlnTrp: 0.927 ± 0.521
1.391GlnTyr: 1.391 ± 0.558
0.0GlnXaa: 0.0 ± 0.0
Arg
4.636ArgAla: 4.636 ± 1.571
0.0ArgCys: 0.0 ± 0.0
0.927ArgAsp: 0.927 ± 0.496
2.318ArgGlu: 2.318 ± 0.751
0.464ArgPhe: 0.464 ± 0.248
5.563ArgGly: 5.563 ± 2.021
2.782ArgHis: 2.782 ± 0.947
1.854ArgIle: 1.854 ± 0.785
3.709ArgLys: 3.709 ± 1.635
4.172ArgLeu: 4.172 ± 0.526
0.927ArgMet: 0.927 ± 0.521
2.782ArgAsn: 2.782 ± 1.832
2.318ArgPro: 2.318 ± 1.235
3.709ArgGln: 3.709 ± 1.476
2.318ArgArg: 2.318 ± 0.905
2.318ArgSer: 2.318 ± 3.128
1.854ArgThr: 1.854 ± 1.011
2.318ArgVal: 2.318 ± 1.241
0.0ArgTrp: 0.0 ± 0.0
2.782ArgTyr: 2.782 ± 1.04
0.0ArgXaa: 0.0 ± 0.0
Ser
4.172SerAla: 4.172 ± 1.803
0.0SerCys: 0.0 ± 0.0
0.464SerAsp: 0.464 ± 0.596
5.1SerGlu: 5.1 ± 1.424
1.854SerPhe: 1.854 ± 0.597
4.172SerGly: 4.172 ± 0.926
1.391SerHis: 1.391 ± 0.52
2.318SerIle: 2.318 ± 1.735
3.709SerLys: 3.709 ± 1.476
3.709SerLeu: 3.709 ± 0.721
2.318SerMet: 2.318 ± 0.935
2.782SerAsn: 2.782 ± 1.034
4.172SerPro: 4.172 ± 1.119
2.318SerGln: 2.318 ± 0.873
2.782SerArg: 2.782 ± 1.66
6.954SerSer: 6.954 ± 5.352
3.709SerThr: 3.709 ± 0.94
0.927SerVal: 0.927 ± 0.496
1.391SerTrp: 1.391 ± 0.83
1.854SerTyr: 1.854 ± 0.693
0.0SerXaa: 0.0 ± 0.0
Thr
7.881ThrAla: 7.881 ± 2.263
1.391ThrCys: 1.391 ± 1.446
4.172ThrAsp: 4.172 ± 0.837
3.709ThrGlu: 3.709 ± 1.536
3.245ThrPhe: 3.245 ± 1.23
7.418ThrGly: 7.418 ± 5.165
2.782ThrHis: 2.782 ± 1.489
6.954ThrIle: 6.954 ± 1.655
7.418ThrLys: 7.418 ± 1.515
11.59ThrLeu: 11.59 ± 3.183
1.854ThrMet: 1.854 ± 0.819
1.854ThrAsn: 1.854 ± 0.993
4.172ThrPro: 4.172 ± 2.142
1.854ThrGln: 1.854 ± 2.341
4.636ThrArg: 4.636 ± 3.772
4.172ThrSer: 4.172 ± 1.648
6.49ThrThr: 6.49 ± 4.135
2.318ThrVal: 2.318 ± 1.047
1.391ThrTrp: 1.391 ± 0.558
2.318ThrTyr: 2.318 ± 0.508
0.0ThrXaa: 0.0 ± 0.0
Val
1.854ValAla: 1.854 ± 1.503
0.0ValCys: 0.0 ± 0.0
3.245ValAsp: 3.245 ± 0.876
2.782ValGlu: 2.782 ± 1.082
1.391ValPhe: 1.391 ± 0.745
0.927ValGly: 0.927 ± 0.898
0.464ValHis: 0.464 ± 0.685
1.854ValIle: 1.854 ± 0.693
3.245ValLys: 3.245 ± 1.092
4.636ValLeu: 4.636 ± 1.532
1.391ValMet: 1.391 ± 0.745
0.927ValAsn: 0.927 ± 0.899
2.318ValPro: 2.318 ± 1.051
2.318ValGln: 2.318 ± 0.905
0.464ValArg: 0.464 ± 0.248
2.782ValSer: 2.782 ± 1.489
4.172ValThr: 4.172 ± 0.999
2.782ValVal: 2.782 ± 0.947
0.464ValTrp: 0.464 ± 0.248
0.464ValTyr: 0.464 ± 0.248
0.0ValXaa: 0.0 ± 0.0
Trp
1.854TrpAla: 1.854 ± 0.993
0.464TrpCys: 0.464 ± 0.596
0.927TrpAsp: 0.927 ± 0.898
0.927TrpGlu: 0.927 ± 0.521
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.927TrpIle: 0.927 ± 0.521
2.318TrpLys: 2.318 ± 1.241
1.391TrpLeu: 1.391 ± 0.745
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.927TrpPro: 0.927 ± 0.555
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.927TrpThr: 0.927 ± 0.899
1.391TrpVal: 1.391 ± 0.745
0.464TrpTrp: 0.464 ± 0.248
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.245TyrAla: 3.245 ± 1.251
0.0TyrCys: 0.0 ± 0.0
2.318TyrAsp: 2.318 ± 1.037
1.391TyrGlu: 1.391 ± 0.745
1.854TyrPhe: 1.854 ± 0.832
0.927TyrGly: 0.927 ± 0.555
0.464TyrHis: 0.464 ± 1.161
2.782TyrIle: 2.782 ± 1.666
2.318TyrLys: 2.318 ± 0.873
3.245TyrLeu: 3.245 ± 0.725
1.391TyrMet: 1.391 ± 0.745
1.854TyrAsn: 1.854 ± 1.493
2.782TyrPro: 2.782 ± 0.724
1.391TyrGln: 1.391 ± 0.52
1.391TyrArg: 1.391 ± 0.52
1.854TyrSer: 1.854 ± 0.993
4.172TyrThr: 4.172 ± 1.145
2.318TyrVal: 2.318 ± 0.848
0.0TyrTrp: 0.0 ± 0.0
0.927TyrTyr: 0.927 ± 0.521
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2158 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski