Amino acid dipepetide frequency for Corynespora cassiicola Philippines

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.981AlaAla: 8.981 ± 0.055	1.259AlaCys: 1.259 ± 0.015	4.125AlaAsp: 4.125 ± 0.03	4.984AlaGlu: 4.984 ± 0.036	3.269AlaPhe: 3.269 ± 0.023	5.905AlaGly: 5.905 ± 0.037	1.936AlaHis: 1.936 ± 0.017	4.294AlaIle: 4.294 ± 0.027	4.065AlaLys: 4.065 ± 0.032	7.783AlaLeu: 7.783 ± 0.035	1.983AlaMet: 1.983 ± 0.017	3.045AlaAsn: 3.045 ± 0.027	5.152AlaPro: 5.152 ± 0.041	3.387AlaGln: 3.387 ± 0.027	5.064AlaArg: 5.064 ± 0.028	7.333AlaSer: 7.333 ± 0.037	5.118AlaThr: 5.118 ± 0.028	5.268AlaVal: 5.268 ± 0.032	1.272AlaTrp: 1.272 ± 0.013	2.281AlaTyr: 2.281 ± 0.017	0.0AlaXaa: 0.0 ± 0.0
Cys	1.102CysAla: 1.102 ± 0.014	0.309CysCys: 0.309 ± 0.009	0.682CysAsp: 0.682 ± 0.012	0.631CysGlu: 0.631 ± 0.01	0.592CysPhe: 0.592 ± 0.009	1.064CysGly: 1.064 ± 0.013	0.38CysHis: 0.38 ± 0.007	0.8CysIle: 0.8 ± 0.01	0.576CysLys: 0.576 ± 0.009	1.341CysLeu: 1.341 ± 0.014	0.326CysMet: 0.326 ± 0.006	0.491CysAsn: 0.491 ± 0.009	0.772CysPro: 0.772 ± 0.012	0.475CysGln: 0.475 ± 0.008	0.89CysArg: 0.89 ± 0.012	1.047CysSer: 1.047 ± 0.012	0.801CysThr: 0.801 ± 0.011	0.865CysVal: 0.865 ± 0.013	0.245CysTrp: 0.245 ± 0.006	0.393CysTyr: 0.393 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.696AspAla: 4.696 ± 0.03	0.64AspCys: 0.64 ± 0.01	3.894AspAsp: 3.894 ± 0.038	4.2AspGlu: 4.2 ± 0.033	2.253AspPhe: 2.253 ± 0.019	3.952AspGly: 3.952 ± 0.026	1.209AspHis: 1.209 ± 0.013	3.011AspIle: 3.011 ± 0.022	2.343AspLys: 2.343 ± 0.021	4.674AspLeu: 4.674 ± 0.028	1.281AspMet: 1.281 ± 0.013	1.744AspAsn: 1.744 ± 0.016	3.284AspPro: 3.284 ± 0.023	1.765AspGln: 1.765 ± 0.017	2.941AspArg: 2.941 ± 0.023	3.859AspSer: 3.859 ± 0.029	2.842AspThr: 2.842 ± 0.022	3.547AspVal: 3.547 ± 0.026	0.952AspTrp: 0.952 ± 0.012	1.592AspTyr: 1.592 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.231GluAla: 5.231 ± 0.033	0.687GluCys: 0.687 ± 0.011	3.948GluAsp: 3.948 ± 0.031	5.223GluGlu: 5.223 ± 0.044	1.948GluPhe: 1.948 ± 0.017	3.954GluGly: 3.954 ± 0.027	1.399GluHis: 1.399 ± 0.014	3.002GluIle: 3.002 ± 0.023	3.804GluLys: 3.804 ± 0.027	5.044GluLeu: 5.044 ± 0.033	1.445GluMet: 1.445 ± 0.016	2.29GluAsn: 2.29 ± 0.018	2.818GluPro: 2.818 ± 0.034	2.419GluGln: 2.419 ± 0.024	3.95GluArg: 3.95 ± 0.029	4.039GluSer: 4.039 ± 0.027	3.217GluThr: 3.217 ± 0.022	3.446GluVal: 3.446 ± 0.026	0.968GluTrp: 0.968 ± 0.012	1.716GluTyr: 1.716 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.201PheAla: 3.201 ± 0.022	0.633PheCys: 0.633 ± 0.008	2.286PheAsp: 2.286 ± 0.018	2.202PheGlu: 2.202 ± 0.016	1.804PhePhe: 1.804 ± 0.018	2.965PheGly: 2.965 ± 0.023	0.944PheHis: 0.944 ± 0.013	1.854PheIle: 1.854 ± 0.017	1.599PheLys: 1.599 ± 0.016	3.584PheLeu: 3.584 ± 0.026	0.8PheMet: 0.8 ± 0.011	1.478PheAsn: 1.478 ± 0.014	2.096PhePro: 2.096 ± 0.019	1.453PheGln: 1.453 ± 0.014	2.007PheArg: 2.007 ± 0.018	3.12PheSer: 3.12 ± 0.022	2.175PheThr: 2.175 ± 0.017	2.461PheVal: 2.461 ± 0.021	0.727PheTrp: 0.727 ± 0.011	1.158PheTyr: 1.158 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.51GlyAla: 5.51 ± 0.034	0.994GlyCys: 0.994 ± 0.013	3.471GlyAsp: 3.471 ± 0.027	3.725GlyGlu: 3.725 ± 0.026	2.916GlyPhe: 2.916 ± 0.023	5.944GlyGly: 5.944 ± 0.052	1.681GlyHis: 1.681 ± 0.017	3.637GlyIle: 3.637 ± 0.026	3.52GlyLys: 3.52 ± 0.027	6.053GlyLeu: 6.053 ± 0.036	1.682GlyMet: 1.682 ± 0.017	2.582GlyAsn: 2.582 ± 0.024	3.388GlyPro: 3.388 ± 0.025	2.502GlyGln: 2.502 ± 0.025	4.271GlyArg: 4.271 ± 0.03	5.47GlySer: 5.47 ± 0.035	3.977GlyThr: 3.977 ± 0.028	4.377GlyVal: 4.377 ± 0.028	1.303GlyTrp: 1.303 ± 0.015	2.165GlyTyr: 2.165 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	2.04HisAla: 2.04 ± 0.018	0.401HisCys: 0.401 ± 0.008	1.315HisAsp: 1.315 ± 0.013	1.347HisGlu: 1.347 ± 0.015	0.983HisPhe: 0.983 ± 0.012	1.782HisGly: 1.782 ± 0.016	0.949HisHis: 0.949 ± 0.016	1.281HisIle: 1.281 ± 0.015	0.935HisLys: 0.935 ± 0.013	2.289HisLeu: 2.289 ± 0.019	0.517HisMet: 0.517 ± 0.008	0.844HisAsn: 0.844 ± 0.011	1.77HisPro: 1.77 ± 0.018	1.024HisGln: 1.024 ± 0.014	1.604HisArg: 1.604 ± 0.017	1.91HisSer: 1.91 ± 0.019	1.369HisThr: 1.369 ± 0.015	1.534HisVal: 1.534 ± 0.015	0.381HisTrp: 0.381 ± 0.008	0.713HisTyr: 0.713 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.293IleAla: 4.293 ± 0.028	0.785IleCys: 0.785 ± 0.011	2.779IleAsp: 2.779 ± 0.02	2.906IleGlu: 2.906 ± 0.021	2.105IlePhe: 2.105 ± 0.019	3.24IleGly: 3.24 ± 0.025	1.255IleHis: 1.255 ± 0.014	2.561IleIle: 2.561 ± 0.024	2.225IleLys: 2.225 ± 0.021	4.576IleLeu: 4.576 ± 0.034	1.058IleMet: 1.058 ± 0.012	1.822IleAsn: 1.822 ± 0.017	3.105IlePro: 3.105 ± 0.019	1.879IleGln: 1.879 ± 0.018	2.801IleArg: 2.801 ± 0.023	3.859IleSer: 3.859 ± 0.025	2.873IleThr: 2.873 ± 0.025	3.194IleVal: 3.194 ± 0.025	0.779IleTrp: 0.779 ± 0.01	1.472IleTyr: 1.472 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.152LysAla: 4.152 ± 0.035	0.549LysCys: 0.549 ± 0.008	2.812LysAsp: 2.812 ± 0.025	3.462LysGlu: 3.462 ± 0.027	1.52LysPhe: 1.52 ± 0.014	3.064LysGly: 3.064 ± 0.023	1.186LysHis: 1.186 ± 0.013	2.31LysIle: 2.31 ± 0.019	3.491LysLys: 3.491 ± 0.045	3.994LysLeu: 3.994 ± 0.026	1.042LysMet: 1.042 ± 0.013	1.826LysAsn: 1.826 ± 0.014	2.743LysPro: 2.743 ± 0.024	1.81LysGln: 1.81 ± 0.017	3.409LysArg: 3.409 ± 0.024	3.459LysSer: 3.459 ± 0.027	2.773LysThr: 2.773 ± 0.021	2.798LysVal: 2.798 ± 0.022	0.739LysTrp: 0.739 ± 0.011	1.406LysTyr: 1.406 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	7.772LeuAla: 7.772 ± 0.03	1.31LeuCys: 1.31 ± 0.014	5.017LeuAsp: 5.017 ± 0.03	5.405LeuGlu: 5.405 ± 0.039	3.429LeuPhe: 3.429 ± 0.025	5.958LeuGly: 5.958 ± 0.034	2.357LeuHis: 2.357 ± 0.022	3.927LeuIle: 3.927 ± 0.025	4.105LeuLys: 4.105 ± 0.031	8.252LeuLeu: 8.252 ± 0.049	1.786LeuMet: 1.786 ± 0.014	3.149LeuAsn: 3.149 ± 0.024	5.645LeuPro: 5.645 ± 0.032	3.697LeuGln: 3.697 ± 0.026	5.676LeuArg: 5.676 ± 0.033	7.171LeuSer: 7.171 ± 0.037	4.577LeuThr: 4.577 ± 0.028	5.396LeuVal: 5.396 ± 0.034	1.265LeuTrp: 1.265 ± 0.015	2.389LeuTyr: 2.389 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.251MetAla: 2.251 ± 0.017	0.29MetCys: 0.29 ± 0.007	1.238MetAsp: 1.238 ± 0.014	1.287MetGlu: 1.287 ± 0.015	0.802MetPhe: 0.802 ± 0.011	1.525MetGly: 1.525 ± 0.018	0.55MetHis: 0.55 ± 0.009	1.005MetIle: 1.005 ± 0.011	1.008MetLys: 1.008 ± 0.014	1.876MetLeu: 1.876 ± 0.018	0.584MetMet: 0.584 ± 0.008	0.846MetAsn: 0.846 ± 0.011	1.322MetPro: 1.322 ± 0.014	0.869MetGln: 0.869 ± 0.012	1.351MetArg: 1.351 ± 0.015	1.832MetSer: 1.832 ± 0.016	1.216MetThr: 1.216 ± 0.015	1.294MetVal: 1.294 ± 0.014	0.296MetTrp: 0.296 ± 0.007	0.574MetTyr: 0.574 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.19AsnAla: 3.19 ± 0.022	0.471AsnCys: 0.471 ± 0.009	1.927AsnAsp: 1.927 ± 0.019	2.036AsnGlu: 2.036 ± 0.019	1.476AsnPhe: 1.476 ± 0.013	2.984AsnGly: 2.984 ± 0.026	0.892AsnHis: 0.892 ± 0.012	2.081AsnIle: 2.081 ± 0.02	1.58AsnLys: 1.58 ± 0.015	3.241AsnLeu: 3.241 ± 0.021	0.883AsnMet: 0.883 ± 0.012	1.492AsnAsn: 1.492 ± 0.019	2.464AsnPro: 2.464 ± 0.019	1.355AsnGln: 1.355 ± 0.017	1.965AsnArg: 1.965 ± 0.018	2.78AsnSer: 2.78 ± 0.023	2.211AsnThr: 2.211 ± 0.02	2.343AsnVal: 2.343 ± 0.019	0.609AsnTrp: 0.609 ± 0.01	1.079AsnTyr: 1.079 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	5.426ProAla: 5.426 ± 0.044	0.659ProCys: 0.659 ± 0.01	3.107ProAsp: 3.107 ± 0.023	3.791ProGlu: 3.791 ± 0.034	2.17ProPhe: 2.17 ± 0.018	3.933ProGly: 3.933 ± 0.03	1.524ProHis: 1.524 ± 0.016	2.631ProIle: 2.631 ± 0.019	2.79ProLys: 2.79 ± 0.024	4.897ProLeu: 4.897 ± 0.029	1.111ProMet: 1.111 ± 0.012	2.324ProAsn: 2.324 ± 0.02	5.496ProPro: 5.496 ± 0.064	2.564ProGln: 2.564 ± 0.026	3.565ProArg: 3.565 ± 0.025	6.139ProSer: 6.139 ± 0.042	4.137ProThr: 4.137 ± 0.034	3.419ProVal: 3.419 ± 0.026	0.828ProTrp: 0.828 ± 0.01	1.589ProTyr: 1.589 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.413GlnAla: 3.413 ± 0.027	0.496GlnCys: 0.496 ± 0.009	2.01GlnAsp: 2.01 ± 0.019	2.319GlnGlu: 2.319 ± 0.021	1.273GlnPhe: 1.273 ± 0.013	2.419GlnGly: 2.419 ± 0.02	1.101GlnHis: 1.101 ± 0.013	1.849GlnIle: 1.849 ± 0.016	1.995GlnLys: 1.995 ± 0.02	3.319GlnLeu: 3.319 ± 0.025	0.852GlnMet: 0.852 ± 0.011	1.631GlnAsn: 1.631 ± 0.018	2.522GlnPro: 2.522 ± 0.028	2.318GlnGln: 2.318 ± 0.041	2.591GlnArg: 2.591 ± 0.021	3.026GlnSer: 3.026 ± 0.024	2.207GlnThr: 2.207 ± 0.02	2.094GlnVal: 2.094 ± 0.017	0.62GlnTrp: 0.62 ± 0.01	1.176GlnTyr: 1.176 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.864ArgAla: 4.864 ± 0.029	0.855ArgCys: 0.855 ± 0.011	3.247ArgAsp: 3.247 ± 0.028	3.766ArgGlu: 3.766 ± 0.029	2.237ArgPhe: 2.237 ± 0.019	3.817ArgGly: 3.817 ± 0.027	1.623ArgHis: 1.623 ± 0.018	3.001ArgIle: 3.001 ± 0.023	3.472ArgLys: 3.472 ± 0.025	5.473ArgLeu: 5.473 ± 0.028	1.353ArgMet: 1.353 ± 0.014	2.365ArgAsn: 2.365 ± 0.017	3.724ArgPro: 3.724 ± 0.028	2.502ArgGln: 2.502 ± 0.021	5.192ArgArg: 5.192 ± 0.044	4.67ArgSer: 4.67 ± 0.034	3.312ArgThr: 3.312 ± 0.021	3.325ArgVal: 3.325 ± 0.022	1.046ArgTrp: 1.046 ± 0.011	1.727ArgTyr: 1.727 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.618SerAla: 6.618 ± 0.037	1.001SerCys: 1.001 ± 0.013	3.992SerAsp: 3.992 ± 0.025	4.012SerGlu: 4.012 ± 0.026	3.115SerPhe: 3.115 ± 0.02	5.366SerGly: 5.366 ± 0.032	2.009SerHis: 2.009 ± 0.016	4.061SerIle: 4.061 ± 0.024	3.67SerLys: 3.67 ± 0.024	7.115SerLeu: 7.115 ± 0.04	1.741SerMet: 1.741 ± 0.016	3.032SerAsn: 3.032 ± 0.022	5.548SerPro: 5.548 ± 0.044	3.107SerGln: 3.107 ± 0.021	4.936SerArg: 4.936 ± 0.037	8.302SerSer: 8.302 ± 0.06	5.404SerThr: 5.404 ± 0.035	4.443SerVal: 4.443 ± 0.027	1.209SerTrp: 1.209 ± 0.013	2.095SerTyr: 2.095 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.083ThrAla: 5.083 ± 0.029	0.859ThrCys: 0.859 ± 0.01	2.668ThrAsp: 2.668 ± 0.014	2.942ThrGlu: 2.942 ± 0.024	2.304ThrPhe: 2.304 ± 0.018	3.96ThrGly: 3.96 ± 0.03	1.374ThrHis: 1.374 ± 0.014	3.074ThrIle: 3.074 ± 0.025	2.564ThrLys: 2.564 ± 0.022	5.235ThrLeu: 5.235 ± 0.035	1.207ThrMet: 1.207 ± 0.014	2.079ThrAsn: 2.079 ± 0.017	4.401ThrPro: 4.401 ± 0.036	2.041ThrGln: 2.041 ± 0.018	3.15ThrArg: 3.15 ± 0.024	5.076ThrSer: 5.076 ± 0.035	4.031ThrThr: 4.031 ± 0.035	3.553ThrVal: 3.553 ± 0.026	0.933ThrTrp: 0.933 ± 0.011	1.639ThrTyr: 1.639 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	5.201ValAla: 5.201 ± 0.029	0.898ValCys: 0.898 ± 0.012	3.552ValAsp: 3.552 ± 0.023	3.828ValGlu: 3.828 ± 0.03	2.506ValPhe: 2.506 ± 0.023	4.16ValGly: 4.16 ± 0.03	1.44ValHis: 1.44 ± 0.015	2.867ValIle: 2.867 ± 0.022	2.79ValLys: 2.79 ± 0.023	5.413ValLeu: 5.413 ± 0.028	1.277ValMet: 1.277 ± 0.013	2.164ValAsn: 2.164 ± 0.019	3.565ValPro: 3.565 ± 0.025	2.38ValGln: 2.38 ± 0.019	3.466ValArg: 3.466 ± 0.026	4.45ValSer: 4.45 ± 0.027	3.279ValThr: 3.279 ± 0.024	4.246ValVal: 4.246 ± 0.03	0.967ValTrp: 0.967 ± 0.012	1.732ValTyr: 1.732 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.24TrpAla: 1.24 ± 0.014	0.241TrpCys: 0.241 ± 0.005	0.931TrpAsp: 0.931 ± 0.013	0.885TrpGlu: 0.885 ± 0.011	0.593TrpPhe: 0.593 ± 0.01	1.077TrpGly: 1.077 ± 0.015	0.398TrpHis: 0.398 ± 0.008	0.873TrpIle: 0.873 ± 0.012	0.867TrpLys: 0.867 ± 0.011	1.462TrpLeu: 1.462 ± 0.015	0.413TrpMet: 0.413 ± 0.008	0.708TrpAsn: 0.708 ± 0.011	0.72TrpPro: 0.72 ± 0.011	0.589TrpGln: 0.589 ± 0.009	1.078TrpArg: 1.078 ± 0.012	1.142TrpSer: 1.142 ± 0.015	0.973TrpThr: 0.973 ± 0.013	0.953TrpVal: 0.953 ± 0.012	0.306TrpTrp: 0.306 ± 0.008	0.489TrpTyr: 0.489 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.238TyrAla: 2.238 ± 0.019	0.447TyrCys: 0.447 ± 0.008	1.679TyrAsp: 1.679 ± 0.016	1.596TyrGlu: 1.596 ± 0.015	1.252TyrPhe: 1.252 ± 0.012	2.1TyrGly: 2.1 ± 0.02	0.78TyrHis: 0.78 ± 0.01	1.446TyrIle: 1.446 ± 0.014	1.148TyrLys: 1.148 ± 0.015	2.664TyrLeu: 2.664 ± 0.021	0.674TyrMet: 0.674 ± 0.01	1.148TyrAsn: 1.148 ± 0.012	1.564TyrPro: 1.564 ± 0.015	1.095TyrGln: 1.095 ± 0.013	1.664TyrArg: 1.664 ± 0.016	2.093TyrSer: 2.093 ± 0.017	1.68TyrThr: 1.68 ± 0.018	1.623TyrVal: 1.623 ± 0.014	0.494TyrTrp: 0.494 ± 0.008	0.952TyrTyr: 0.952 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 17125 proteins (7195570 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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