Amino acid dipepetide frequency for Mycoplasma struthionis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.71AlaAla: 3.71 ± 0.204
0.32AlaCys: 0.32 ± 0.04
2.673AlaAsp: 2.673 ± 0.14
3.666AlaGlu: 3.666 ± 0.19
2.887AlaPhe: 2.887 ± 0.111
2.862AlaGly: 2.862 ± 0.17
0.678AlaHis: 0.678 ± 0.063
5.502AlaIle: 5.502 ± 0.184
7.12AlaLys: 7.12 ± 0.267
6.412AlaLeu: 6.412 ± 0.201
1.138AlaMet: 1.138 ± 0.09
4.48AlaAsn: 4.48 ± 0.165
1.53AlaPro: 1.53 ± 0.105
1.986AlaGln: 1.986 ± 0.132
1.971AlaArg: 1.971 ± 0.124
4.03AlaSer: 4.03 ± 0.14
3.337AlaThr: 3.337 ± 0.132
2.93AlaVal: 2.93 ± 0.154
0.412AlaTrp: 0.412 ± 0.043
2.451AlaTyr: 2.451 ± 0.097
0.0AlaXaa: 0.0 ± 0.0
Cys
0.32CysAla: 0.32 ± 0.045
0.039CysCys: 0.039 ± 0.015
0.281CysAsp: 0.281 ± 0.037
0.407CysGlu: 0.407 ± 0.046
0.291CysPhe: 0.291 ± 0.04
0.295CysGly: 0.295 ± 0.038
0.073CysHis: 0.073 ± 0.022
0.271CysIle: 0.271 ± 0.032
0.305CysLys: 0.305 ± 0.04
0.484CysLeu: 0.484 ± 0.057
0.073CysMet: 0.073 ± 0.017
0.232CysAsn: 0.232 ± 0.033
0.165CysPro: 0.165 ± 0.031
0.189CysGln: 0.189 ± 0.028
0.15CysArg: 0.15 ± 0.025
0.228CysSer: 0.228 ± 0.04
0.17CysThr: 0.17 ± 0.025
0.262CysVal: 0.262 ± 0.035
0.044CysTrp: 0.044 ± 0.017
0.136CysTyr: 0.136 ± 0.025
0.0CysXaa: 0.0 ± 0.0
Asp
3.419AspAla: 3.419 ± 0.186
0.203AspCys: 0.203 ± 0.035
2.746AspAsp: 2.746 ± 0.116
4.315AspGlu: 4.315 ± 0.179
4.049AspPhe: 4.049 ± 0.163
2.368AspGly: 2.368 ± 0.125
0.697AspHis: 0.697 ± 0.062
4.945AspIle: 4.945 ± 0.166
5.458AspLys: 5.458 ± 0.211
6.219AspLeu: 6.219 ± 0.18
0.872AspMet: 0.872 ± 0.074
4.054AspAsn: 4.054 ± 0.165
1.744AspPro: 1.744 ± 0.109
1.618AspGln: 1.618 ± 0.117
1.39AspArg: 1.39 ± 0.088
3.337AspSer: 3.337 ± 0.15
2.436AspThr: 2.436 ± 0.128
3.09AspVal: 3.09 ± 0.138
0.567AspTrp: 0.567 ± 0.061
3.003AspTyr: 3.003 ± 0.127
0.0AspXaa: 0.0 ± 0.0
Glu
4.722GluAla: 4.722 ± 0.221
0.17GluCys: 0.17 ± 0.033
3.787GluAsp: 3.787 ± 0.172
5.255GluGlu: 5.255 ± 0.215
3.531GluPhe: 3.531 ± 0.142
2.659GluGly: 2.659 ± 0.132
0.872GluHis: 0.872 ± 0.07
7.367GluIle: 7.367 ± 0.205
8.108GluLys: 8.108 ± 0.244
7.003GluLeu: 7.003 ± 0.249
1.308GluMet: 1.308 ± 0.087
7.178GluAsn: 7.178 ± 0.185
1.448GluPro: 1.448 ± 0.079
2.262GluGln: 2.262 ± 0.118
2.054GluArg: 2.054 ± 0.101
3.085GluSer: 3.085 ± 0.129
3.506GluThr: 3.506 ± 0.149
3.933GluVal: 3.933 ± 0.142
0.392GluTrp: 0.392 ± 0.047
3.027GluTyr: 3.027 ± 0.123
0.0GluXaa: 0.0 ± 0.0
Phe
3.197PheAla: 3.197 ± 0.145
0.329PheCys: 0.329 ± 0.039
3.637PheAsp: 3.637 ± 0.134
3.686PheGlu: 3.686 ± 0.144
2.363PhePhe: 2.363 ± 0.135
2.485PheGly: 2.485 ± 0.106
0.61PheHis: 0.61 ± 0.054
4.553PheIle: 4.553 ± 0.223
5.361PheLys: 5.361 ± 0.171
4.853PheLeu: 4.853 ± 0.236
0.857PheMet: 0.857 ± 0.065
4.335PheAsn: 4.335 ± 0.172
1.007PhePro: 1.007 ± 0.076
1.128PheGln: 1.128 ± 0.083
1.434PheArg: 1.434 ± 0.078
4.165PheSer: 4.165 ± 0.188
2.252PheThr: 2.252 ± 0.123
2.848PheVal: 2.848 ± 0.146
0.45PheTrp: 0.45 ± 0.052
2.131PheTyr: 2.131 ± 0.121
0.0PheXaa: 0.0 ± 0.0
Gly
2.722GlyAla: 2.722 ± 0.158
0.136GlyCys: 0.136 ± 0.022
2.567GlyAsp: 2.567 ± 0.145
2.591GlyGlu: 2.591 ± 0.14
2.615GlyPhe: 2.615 ± 0.152
2.572GlyGly: 2.572 ± 0.16
0.857GlyHis: 0.857 ± 0.076
3.976GlyIle: 3.976 ± 0.165
3.836GlyLys: 3.836 ± 0.152
4.238GlyLeu: 4.238 ± 0.174
0.804GlyMet: 0.804 ± 0.069
2.698GlyAsn: 2.698 ± 0.111
1.477GlyPro: 1.477 ± 0.164
1.763GlyGln: 1.763 ± 0.098
1.671GlyArg: 1.671 ± 0.104
2.901GlySer: 2.901 ± 0.141
2.233GlyThr: 2.233 ± 0.118
2.63GlyVal: 2.63 ± 0.123
0.412GlyTrp: 0.412 ± 0.053
2.189GlyTyr: 2.189 ± 0.093
0.0GlyXaa: 0.0 ± 0.0
His
0.804HisAla: 0.804 ± 0.063
0.058HisCys: 0.058 ± 0.016
0.528HisAsp: 0.528 ± 0.048
0.993HisGlu: 0.993 ± 0.06
0.712HisPhe: 0.712 ± 0.066
0.877HisGly: 0.877 ± 0.07
0.252HisHis: 0.252 ± 0.041
1.085HisIle: 1.085 ± 0.072
1.051HisLys: 1.051 ± 0.082
1.259HisLeu: 1.259 ± 0.079
0.184HisMet: 0.184 ± 0.024
0.911HisAsn: 0.911 ± 0.07
0.523HisPro: 0.523 ± 0.047
0.402HisGln: 0.402 ± 0.038
0.349HisArg: 0.349 ± 0.04
0.973HisSer: 0.973 ± 0.078
0.552HisThr: 0.552 ± 0.058
0.736HisVal: 0.736 ± 0.073
0.126HisTrp: 0.126 ± 0.025
0.644HisTyr: 0.644 ± 0.052
0.0HisXaa: 0.0 ± 0.0
Ile
5.216IleAla: 5.216 ± 0.187
0.523IleCys: 0.523 ± 0.054
5.25IleAsp: 5.25 ± 0.177
6.18IleGlu: 6.18 ± 0.212
4.504IlePhe: 4.504 ± 0.238
3.526IleGly: 3.526 ± 0.163
0.944IleHis: 0.944 ± 0.071
7.754IleIle: 7.754 ± 0.32
10.03IleLys: 10.03 ± 0.246
7.57IleLeu: 7.57 ± 0.241
1.385IleMet: 1.385 ± 0.09
7.517IleAsn: 7.517 ± 0.234
2.548IlePro: 2.548 ± 0.12
2.422IleGln: 2.422 ± 0.108
2.533IleArg: 2.533 ± 0.105
6.393IleSer: 6.393 ± 0.225
4.649IleThr: 4.649 ± 0.161
4.649IleVal: 4.649 ± 0.174
0.625IleTrp: 0.625 ± 0.068
3.293IleTyr: 3.293 ± 0.142
0.0IleXaa: 0.0 ± 0.0
Lys
6.214LysAla: 6.214 ± 0.263
0.271LysCys: 0.271 ± 0.043
6.131LysAsp: 6.131 ± 0.16
9.086LysGlu: 9.086 ± 0.261
4.296LysPhe: 4.296 ± 0.158
4.01LysGly: 4.01 ± 0.195
1.337LysHis: 1.337 ± 0.073
9.653LysIle: 9.653 ± 0.294
11.207LysLys: 11.207 ± 0.299
9.517LysLeu: 9.517 ± 0.262
2.276LysMet: 2.276 ± 0.133
9.478LysAsn: 9.478 ± 0.296
2.736LysPro: 2.736 ± 0.133
3.962LysGln: 3.962 ± 0.197
3.39LysArg: 3.39 ± 0.137
5.444LysSer: 5.444 ± 0.187
5.55LysThr: 5.55 ± 0.165
5.221LysVal: 5.221 ± 0.172
0.867LysTrp: 0.867 ± 0.085
4.587LysTyr: 4.587 ± 0.161
0.0LysXaa: 0.0 ± 0.0
Leu
6.461LeuAla: 6.461 ± 0.207
0.431LeuCys: 0.431 ± 0.046
6.136LeuAsp: 6.136 ± 0.219
7.328LeuGlu: 7.328 ± 0.246
4.959LeuPhe: 4.959 ± 0.218
4.378LeuGly: 4.378 ± 0.167
1.158LeuHis: 1.158 ± 0.069
8.316LeuIle: 8.316 ± 0.299
11.125LeuLys: 11.125 ± 0.293
8.626LeuLeu: 8.626 ± 0.285
1.492LeuMet: 1.492 ± 0.088
8.548LeuAsn: 8.548 ± 0.301
2.518LeuPro: 2.518 ± 0.126
2.489LeuGln: 2.489 ± 0.143
2.722LeuArg: 2.722 ± 0.117
6.766LeuSer: 6.766 ± 0.164
5.066LeuThr: 5.066 ± 0.162
5.691LeuVal: 5.691 ± 0.192
0.697LeuTrp: 0.697 ± 0.065
3.279LeuTyr: 3.279 ± 0.137
0.0LeuXaa: 0.0 ± 0.0
Met
1.308MetAla: 1.308 ± 0.099
0.082MetCys: 0.082 ± 0.023
0.726MetAsp: 0.726 ± 0.059
0.823MetGlu: 0.823 ± 0.065
1.07MetPhe: 1.07 ± 0.108
0.726MetGly: 0.726 ± 0.056
0.208MetHis: 0.208 ± 0.029
1.434MetIle: 1.434 ± 0.089
1.85MetLys: 1.85 ± 0.104
1.685MetLeu: 1.685 ± 0.105
0.363MetMet: 0.363 ± 0.04
1.128MetAsn: 1.128 ± 0.087
0.736MetPro: 0.736 ± 0.061
0.591MetGln: 0.591 ± 0.05
0.562MetArg: 0.562 ± 0.053
1.298MetSer: 1.298 ± 0.094
0.891MetThr: 0.891 ± 0.062
0.862MetVal: 0.862 ± 0.07
0.102MetTrp: 0.102 ± 0.021
0.547MetTyr: 0.547 ± 0.055
0.0MetXaa: 0.0 ± 0.0
Asn
4.199AsnAla: 4.199 ± 0.232
0.271AsnCys: 0.271 ± 0.036
4.504AsnAsp: 4.504 ± 0.152
6.238AsnGlu: 6.238 ± 0.201
3.758AsnPhe: 3.758 ± 0.166
3.366AsnGly: 3.366 ± 0.164
1.07AsnHis: 1.07 ± 0.076
6.824AsnIle: 6.824 ± 0.196
9.12AsnLys: 9.12 ± 0.254
8.451AsnLeu: 8.451 ± 0.26
1.264AsnMet: 1.264 ± 0.083
7.192AsnAsn: 7.192 ± 0.28
2.577AsnPro: 2.577 ± 0.106
3.284AsnGln: 3.284 ± 0.15
2.087AsnArg: 2.087 ± 0.105
5.284AsnSer: 5.284 ± 0.208
3.453AsnThr: 3.453 ± 0.155
3.841AsnVal: 3.841 ± 0.144
0.862AsnTrp: 0.862 ± 0.076
3.608AsnTyr: 3.608 ± 0.132
0.0AsnXaa: 0.0 ± 0.0
Pro
1.961ProAla: 1.961 ± 0.134
0.126ProCys: 0.126 ± 0.021
1.264ProAsp: 1.264 ± 0.081
2.417ProGlu: 2.417 ± 0.098
1.39ProPhe: 1.39 ± 0.07
1.361ProGly: 1.361 ± 0.089
0.397ProHis: 0.397 ± 0.046
2.155ProIle: 2.155 ± 0.107
2.799ProLys: 2.799 ± 0.122
2.518ProLeu: 2.518 ± 0.122
0.417ProMet: 0.417 ± 0.054
1.923ProAsn: 1.923 ± 0.106
0.465ProPro: 0.465 ± 0.047
1.158ProGln: 1.158 ± 0.086
0.794ProArg: 0.794 ± 0.075
1.811ProSer: 1.811 ± 0.088
1.661ProThr: 1.661 ± 0.114
1.685ProVal: 1.685 ± 0.1
0.295ProTrp: 0.295 ± 0.045
1.23ProTyr: 1.23 ± 0.078
0.0ProXaa: 0.0 ± 0.0
Gln
1.981GlnAla: 1.981 ± 0.12
0.077GlnCys: 0.077 ± 0.016
1.947GlnAsp: 1.947 ± 0.13
2.325GlnGlu: 2.325 ± 0.131
1.429GlnPhe: 1.429 ± 0.077
1.434GlnGly: 1.434 ± 0.116
0.417GlnHis: 0.417 ± 0.046
3.032GlnIle: 3.032 ± 0.133
4.039GlnLys: 4.039 ± 0.213
2.64GlnLeu: 2.64 ± 0.138
0.567GlnMet: 0.567 ± 0.049
2.911GlnAsn: 2.911 ± 0.164
0.973GlnPro: 0.973 ± 0.085
1.041GlnGln: 1.041 ± 0.08
1.022GlnArg: 1.022 ± 0.066
1.56GlnSer: 1.56 ± 0.088
1.811GlnThr: 1.811 ± 0.088
1.511GlnVal: 1.511 ± 0.09
0.232GlnTrp: 0.232 ± 0.035
1.133GlnTyr: 1.133 ± 0.076
0.0GlnXaa: 0.0 ± 0.0
Arg
1.7ArgAla: 1.7 ± 0.088
0.15ArgCys: 0.15 ± 0.025
1.836ArgAsp: 1.836 ± 0.103
2.165ArgGlu: 2.165 ± 0.117
1.506ArgPhe: 1.506 ± 0.074
1.613ArgGly: 1.613 ± 0.121
0.446ArgHis: 0.446 ± 0.05
2.533ArgIle: 2.533 ± 0.13
2.77ArgLys: 2.77 ± 0.111
2.872ArgLeu: 2.872 ± 0.14
0.634ArgMet: 0.634 ± 0.068
2.068ArgAsn: 2.068 ± 0.119
0.925ArgPro: 0.925 ± 0.084
1.036ArgGln: 1.036 ± 0.071
1.143ArgArg: 1.143 ± 0.078
1.714ArgSer: 1.714 ± 0.093
1.598ArgThr: 1.598 ± 0.091
1.836ArgVal: 1.836 ± 0.1
0.237ArgTrp: 0.237 ± 0.034
1.313ArgTyr: 1.313 ± 0.084
0.0ArgXaa: 0.0 ± 0.0
Ser
3.337SerAla: 3.337 ± 0.15
0.547SerCys: 0.547 ± 0.052
3.618SerAsp: 3.618 ± 0.163
4.422SerGlu: 4.422 ± 0.143
3.816SerPhe: 3.816 ± 0.153
3.138SerGly: 3.138 ± 0.143
0.964SerHis: 0.964 ± 0.077
5.347SerIle: 5.347 ± 0.197
6.127SerLys: 6.127 ± 0.19
7.095SerLeu: 7.095 ± 0.245
1.036SerMet: 1.036 ± 0.074
4.921SerAsn: 4.921 ± 0.192
1.652SerPro: 1.652 ± 0.092
2.305SerGln: 2.305 ± 0.09
1.816SerArg: 1.816 ± 0.109
4.853SerSer: 4.853 ± 0.176
3.366SerThr: 3.366 ± 0.157
3.158SerVal: 3.158 ± 0.13
0.557SerTrp: 0.557 ± 0.055
2.518SerTyr: 2.518 ± 0.123
0.0SerXaa: 0.0 ± 0.0
Thr
2.615ThrAla: 2.615 ± 0.127
0.155ThrCys: 0.155 ± 0.038
2.494ThrAsp: 2.494 ± 0.125
2.983ThrGlu: 2.983 ± 0.136
2.819ThrPhe: 2.819 ± 0.14
2.378ThrGly: 2.378 ± 0.122
0.731ThrHis: 0.731 ± 0.055
4.427ThrIle: 4.427 ± 0.16
5.231ThrLys: 5.231 ± 0.16
5.303ThrLeu: 5.303 ± 0.179
0.659ThrMet: 0.659 ± 0.058
3.962ThrAsn: 3.962 ± 0.151
1.937ThrPro: 1.937 ± 0.119
1.477ThrGln: 1.477 ± 0.1
1.656ThrArg: 1.656 ± 0.108
3.337ThrSer: 3.337 ± 0.129
2.843ThrThr: 2.843 ± 0.129
3.1ThrVal: 3.1 ± 0.128
0.494ThrTrp: 0.494 ± 0.045
1.821ThrTyr: 1.821 ± 0.107
0.0ThrXaa: 0.0 ± 0.0
Val
3.715ValAla: 3.715 ± 0.168
0.315ValCys: 0.315 ± 0.043
3.429ValAsp: 3.429 ± 0.147
3.444ValGlu: 3.444 ± 0.144
2.94ValPhe: 2.94 ± 0.138
2.417ValGly: 2.417 ± 0.14
0.722ValHis: 0.722 ± 0.069
4.272ValIle: 4.272 ± 0.169
4.809ValLys: 4.809 ± 0.175
5.783ValLeu: 5.783 ± 0.188
0.852ValMet: 0.852 ± 0.067
4.049ValAsn: 4.049 ± 0.164
1.438ValPro: 1.438 ± 0.091
1.274ValGln: 1.274 ± 0.085
1.695ValArg: 1.695 ± 0.094
4.151ValSer: 4.151 ± 0.133
2.659ValThr: 2.659 ± 0.127
3.071ValVal: 3.071 ± 0.161
0.523ValTrp: 0.523 ± 0.053
2.17ValTyr: 2.17 ± 0.12
0.0ValXaa: 0.0 ± 0.0
Trp
0.421TrpAla: 0.421 ± 0.049
0.019TrpCys: 0.019 ± 0.01
0.586TrpAsp: 0.586 ± 0.066
0.484TrpGlu: 0.484 ± 0.049
0.397TrpPhe: 0.397 ± 0.052
0.402TrpGly: 0.402 ± 0.044
0.097TrpHis: 0.097 ± 0.021
0.794TrpIle: 0.794 ± 0.068
0.828TrpLys: 0.828 ± 0.068
0.693TrpLeu: 0.693 ± 0.07
0.208TrpMet: 0.208 ± 0.033
0.726TrpAsn: 0.726 ± 0.073
0.213TrpPro: 0.213 ± 0.033
0.199TrpGln: 0.199 ± 0.029
0.291TrpArg: 0.291 ± 0.037
0.441TrpSer: 0.441 ± 0.049
0.499TrpThr: 0.499 ± 0.052
0.412TrpVal: 0.412 ± 0.043
0.073TrpTrp: 0.073 ± 0.021
0.586TrpTyr: 0.586 ± 0.059
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.073TyrAla: 2.073 ± 0.092
0.189TyrCys: 0.189 ± 0.032
2.388TyrAsp: 2.388 ± 0.085
2.857TyrGlu: 2.857 ± 0.129
2.349TyrPhe: 2.349 ± 0.118
2.02TyrGly: 2.02 ± 0.114
0.489TyrHis: 0.489 ± 0.05
3.274TyrIle: 3.274 ± 0.127
4.059TyrLys: 4.059 ± 0.158
4.969TyrLeu: 4.969 ± 0.184
0.601TyrMet: 0.601 ± 0.065
2.945TyrAsn: 2.945 ± 0.112
1.216TyrPro: 1.216 ± 0.07
1.497TyrGln: 1.497 ± 0.102
1.366TyrArg: 1.366 ± 0.085
2.824TyrSer: 2.824 ± 0.116
1.889TyrThr: 1.889 ± 0.104
2.262TyrVal: 2.262 ± 0.116
0.402TyrTrp: 0.402 ± 0.05
1.748TyrTyr: 1.748 ± 0.098
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 590 proteins (206476 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski