Amino acid dipepetide frequency for Roseivivax roseus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.238AlaAla: 18.238 ± 0.193	1.081AlaCys: 1.081 ± 0.034	7.475AlaAsp: 7.475 ± 0.091	8.858AlaGlu: 8.858 ± 0.093	4.313AlaPhe: 4.313 ± 0.066	11.286AlaGly: 11.286 ± 0.102	2.284AlaHis: 2.284 ± 0.046	5.522AlaIle: 5.522 ± 0.068	2.733AlaLys: 2.733 ± 0.053	14.206AlaLeu: 14.206 ± 0.146	3.808AlaMet: 3.808 ± 0.06	2.309AlaAsn: 2.309 ± 0.043	6.36AlaPro: 6.36 ± 0.095	4.166AlaGln: 4.166 ± 0.059	9.72AlaArg: 9.72 ± 0.104	5.4AlaSer: 5.4 ± 0.082	6.285AlaThr: 6.285 ± 0.073	9.02AlaVal: 9.02 ± 0.107	1.673AlaTrp: 1.673 ± 0.038	2.417AlaTyr: 2.417 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.06CysAla: 1.06 ± 0.034	0.115CysCys: 0.115 ± 0.01	0.604CysAsp: 0.604 ± 0.02	0.433CysGlu: 0.433 ± 0.019	0.292CysPhe: 0.292 ± 0.016	0.943CysGly: 0.943 ± 0.035	0.259CysHis: 0.259 ± 0.015	0.366CysIle: 0.366 ± 0.018	0.142CysLys: 0.142 ± 0.01	0.939CysLeu: 0.939 ± 0.026	0.133CysMet: 0.133 ± 0.009	0.185CysAsn: 0.185 ± 0.015	0.496CysPro: 0.496 ± 0.024	0.189CysGln: 0.189 ± 0.012	0.603CysArg: 0.603 ± 0.022	0.39CysSer: 0.39 ± 0.017	0.444CysThr: 0.444 ± 0.02	0.617CysVal: 0.617 ± 0.022	0.107CysTrp: 0.107 ± 0.008	0.168CysTyr: 0.168 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.98AspAla: 7.98 ± 0.088	0.473AspCys: 0.473 ± 0.021	3.976AspAsp: 3.976 ± 0.083	4.228AspGlu: 4.228 ± 0.06	2.268AspPhe: 2.268 ± 0.037	6.276AspGly: 6.276 ± 0.093	1.341AspHis: 1.341 ± 0.036	2.952AspIle: 2.952 ± 0.047	1.313AspLys: 1.313 ± 0.032	6.516AspLeu: 6.516 ± 0.085	1.591AspMet: 1.591 ± 0.04	1.174AspAsn: 1.174 ± 0.033	3.97AspPro: 3.97 ± 0.069	1.676AspGln: 1.676 ± 0.04	5.216AspArg: 5.216 ± 0.072	2.525AspSer: 2.525 ± 0.054	3.393AspThr: 3.393 ± 0.058	4.397AspVal: 4.397 ± 0.063	1.24AspTrp: 1.24 ± 0.038	1.485AspTyr: 1.485 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	8.521GluAla: 8.521 ± 0.085	0.375GluCys: 0.375 ± 0.019	3.73GluAsp: 3.73 ± 0.067	3.868GluGlu: 3.868 ± 0.071	1.62GluPhe: 1.62 ± 0.039	5.346GluGly: 5.346 ± 0.068	1.12GluHis: 1.12 ± 0.037	3.622GluIle: 3.622 ± 0.055	1.694GluLys: 1.694 ± 0.042	5.243GluLeu: 5.243 ± 0.058	1.979GluMet: 1.979 ± 0.038	1.531GluAsn: 1.531 ± 0.042	2.848GluPro: 2.848 ± 0.051	1.976GluGln: 1.976 ± 0.042	5.097GluArg: 5.097 ± 0.071	2.597GluSer: 2.597 ± 0.046	4.504GluThr: 4.504 ± 0.059	4.566GluVal: 4.566 ± 0.068	0.735GluTrp: 0.735 ± 0.022	1.04GluTyr: 1.04 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.413PheAla: 4.413 ± 0.058	0.387PheCys: 0.387 ± 0.018	2.848PheAsp: 2.848 ± 0.053	2.136PheGlu: 2.136 ± 0.046	1.334PhePhe: 1.334 ± 0.041	3.669PheGly: 3.669 ± 0.056	0.755PheHis: 0.755 ± 0.022	1.34PheIle: 1.34 ± 0.037	0.68PheLys: 0.68 ± 0.025	3.375PheLeu: 3.375 ± 0.058	0.729PheMet: 0.729 ± 0.024	0.932PheAsn: 0.932 ± 0.028	1.591PhePro: 1.591 ± 0.039	0.893PheGln: 0.893 ± 0.029	2.291PheArg: 2.291 ± 0.041	1.953PheSer: 1.953 ± 0.042	1.904PheThr: 1.904 ± 0.041	2.708PheVal: 2.708 ± 0.048	0.585PheTrp: 0.585 ± 0.022	0.864PheTyr: 0.864 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	10.825GlyAla: 10.825 ± 0.112	0.85GlyCys: 0.85 ± 0.03	5.231GlyAsp: 5.231 ± 0.083	5.111GlyGlu: 5.111 ± 0.067	3.485GlyPhe: 3.485 ± 0.055	8.105GlyGly: 8.105 ± 0.126	1.98GlyHis: 1.98 ± 0.043	4.338GlyIle: 4.338 ± 0.063	2.372GlyLys: 2.372 ± 0.056	9.678GlyLeu: 9.678 ± 0.109	2.588GlyMet: 2.588 ± 0.05	1.893GlyAsn: 1.893 ± 0.057	4.192GlyPro: 4.192 ± 0.059	3.052GlyGln: 3.052 ± 0.046	6.663GlyArg: 6.663 ± 0.088	4.308GlySer: 4.308 ± 0.067	5.233GlyThr: 5.233 ± 0.086	6.614GlyVal: 6.614 ± 0.071	1.508GlyTrp: 1.508 ± 0.035	2.296GlyTyr: 2.296 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.452HisAla: 2.452 ± 0.047	0.22HisCys: 0.22 ± 0.013	1.376HisAsp: 1.376 ± 0.041	1.127HisGlu: 1.127 ± 0.032	0.728HisPhe: 0.728 ± 0.024	2.044HisGly: 2.044 ± 0.043	0.549HisHis: 0.549 ± 0.025	0.81HisIle: 0.81 ± 0.029	0.403HisLys: 0.403 ± 0.018	2.028HisLeu: 2.028 ± 0.038	0.495HisMet: 0.495 ± 0.021	0.387HisAsn: 0.387 ± 0.016	1.339HisPro: 1.339 ± 0.037	0.467HisGln: 0.467 ± 0.021	1.48HisArg: 1.48 ± 0.033	0.829HisSer: 0.829 ± 0.025	0.786HisThr: 0.786 ± 0.02	1.652HisVal: 1.652 ± 0.039	0.356HisTrp: 0.356 ± 0.016	0.476HisTyr: 0.476 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.625IleAla: 6.625 ± 0.08	0.523IleCys: 0.523 ± 0.022	3.527IleAsp: 3.527 ± 0.052	3.32IleGlu: 3.32 ± 0.052	1.572IlePhe: 1.572 ± 0.036	4.699IleGly: 4.699 ± 0.071	0.852IleHis: 0.852 ± 0.024	1.671IleIle: 1.671 ± 0.047	0.944IleLys: 0.944 ± 0.032	4.424IleLeu: 4.424 ± 0.072	0.861IleMet: 0.861 ± 0.029	1.068IleAsn: 1.068 ± 0.028	2.163IlePro: 2.163 ± 0.039	0.991IleGln: 0.991 ± 0.03	3.066IleArg: 3.066 ± 0.047	2.545IleSer: 2.545 ± 0.048	2.39IleThr: 2.39 ± 0.047	3.924IleVal: 3.924 ± 0.059	0.622IleTrp: 0.622 ± 0.021	1.049IleTyr: 1.049 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.892LysAla: 2.892 ± 0.059	0.137LysCys: 0.137 ± 0.01	1.334LysAsp: 1.334 ± 0.038	1.288LysGlu: 1.288 ± 0.034	0.674LysPhe: 0.674 ± 0.028	2.043LysGly: 2.043 ± 0.045	0.456LysHis: 0.456 ± 0.019	1.218LysIle: 1.218 ± 0.032	0.863LysLys: 0.863 ± 0.032	2.173LysLeu: 2.173 ± 0.047	0.672LysMet: 0.672 ± 0.027	0.554LysAsn: 0.554 ± 0.023	1.298LysPro: 1.298 ± 0.035	0.677LysGln: 0.677 ± 0.024	1.888LysArg: 1.888 ± 0.043	1.35LysSer: 1.35 ± 0.037	1.526LysThr: 1.526 ± 0.037	1.829LysVal: 1.829 ± 0.034	0.288LysTrp: 0.288 ± 0.015	0.486LysTyr: 0.486 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.252LeuAla: 13.252 ± 0.134	0.98LeuCys: 0.98 ± 0.033	6.643LeuAsp: 6.643 ± 0.08	5.374LeuGlu: 5.374 ± 0.068	3.472LeuPhe: 3.472 ± 0.069	8.867LeuGly: 8.867 ± 0.1	1.874LeuHis: 1.874 ± 0.034	4.73LeuIle: 4.73 ± 0.069	2.489LeuLys: 2.489 ± 0.054	9.082LeuLeu: 9.082 ± 0.141	2.504LeuMet: 2.504 ± 0.045	2.251LeuAsn: 2.251 ± 0.044	5.495LeuPro: 5.495 ± 0.082	2.514LeuGln: 2.514 ± 0.043	7.594LeuArg: 7.594 ± 0.085	6.858LeuSer: 6.858 ± 0.082	6.045LeuThr: 6.045 ± 0.075	7.47LeuVal: 7.47 ± 0.101	1.33LeuTrp: 1.33 ± 0.038	1.979LeuTyr: 1.979 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	3.331MetAla: 3.331 ± 0.053	0.174MetCys: 0.174 ± 0.012	1.364MetAsp: 1.364 ± 0.035	1.356MetGlu: 1.356 ± 0.031	0.756MetPhe: 0.756 ± 0.026	2.141MetGly: 2.141 ± 0.041	0.456MetHis: 0.456 ± 0.021	1.359MetIle: 1.359 ± 0.037	0.841MetLys: 0.841 ± 0.027	2.514MetLeu: 2.514 ± 0.046	0.723MetMet: 0.723 ± 0.028	0.709MetAsn: 0.709 ± 0.025	1.589MetPro: 1.589 ± 0.036	0.888MetGln: 0.888 ± 0.028	1.93MetArg: 1.93 ± 0.043	1.787MetSer: 1.787 ± 0.035	2.098MetThr: 2.098 ± 0.041	1.781MetVal: 1.781 ± 0.041	0.236MetTrp: 0.236 ± 0.015	0.349MetTyr: 0.349 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.815AsnAla: 2.815 ± 0.056	0.185AsnCys: 0.185 ± 0.014	1.319AsnAsp: 1.319 ± 0.038	1.096AsnGlu: 1.096 ± 0.035	0.813AsnPhe: 0.813 ± 0.024	2.092AsnGly: 2.092 ± 0.055	0.426AsnHis: 0.426 ± 0.017	1.168AsnIle: 1.168 ± 0.031	0.452AsnLys: 0.452 ± 0.023	2.153AsnLeu: 2.153 ± 0.043	0.588AsnMet: 0.588 ± 0.023	0.553AsnAsn: 0.553 ± 0.022	1.544AsnPro: 1.544 ± 0.031	0.57AsnGln: 0.57 ± 0.019	1.622AsnArg: 1.622 ± 0.036	0.984AsnSer: 0.984 ± 0.031	1.099AsnThr: 1.099 ± 0.03	1.787AsnVal: 1.787 ± 0.038	0.378AsnTrp: 0.378 ± 0.016	0.563AsnTyr: 0.563 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.212ProAla: 6.212 ± 0.079	0.369ProCys: 0.369 ± 0.019	4.47ProAsp: 4.47 ± 0.065	4.601ProGlu: 4.601 ± 0.066	1.917ProPhe: 1.917 ± 0.036	4.847ProGly: 4.847 ± 0.069	1.045ProHis: 1.045 ± 0.032	2.053ProIle: 2.053 ± 0.043	1.223ProLys: 1.223 ± 0.032	4.776ProLeu: 4.776 ± 0.071	1.275ProMet: 1.275 ± 0.033	1.16ProAsn: 1.16 ± 0.029	2.629ProPro: 2.629 ± 0.048	1.637ProGln: 1.637 ± 0.032	3.178ProArg: 3.178 ± 0.054	2.544ProSer: 2.544 ± 0.046	2.432ProThr: 2.432 ± 0.046	4.458ProVal: 4.458 ± 0.061	0.689ProTrp: 0.689 ± 0.029	1.082ProTyr: 1.082 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.721GlnAla: 3.721 ± 0.058	0.184GlnCys: 0.184 ± 0.013	1.687GlnAsp: 1.687 ± 0.036	1.662GlnGlu: 1.662 ± 0.039	0.917GlnPhe: 0.917 ± 0.029	2.485GlnGly: 2.485 ± 0.05	0.493GlnHis: 0.493 ± 0.023	1.643GlnIle: 1.643 ± 0.038	0.87GlnLys: 0.87 ± 0.029	2.614GlnLeu: 2.614 ± 0.049	0.919GlnMet: 0.919 ± 0.032	0.764GlnAsn: 0.764 ± 0.027	1.55GlnPro: 1.55 ± 0.037	1.137GlnGln: 1.137 ± 0.039	2.233GlnArg: 2.233 ± 0.04	1.667GlnSer: 1.667 ± 0.04	1.76GlnThr: 1.76 ± 0.042	2.163GlnVal: 2.163 ± 0.037	0.366GlnTrp: 0.366 ± 0.014	0.54GlnTyr: 0.54 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	8.978ArgAla: 8.978 ± 0.102	0.476ArgCys: 0.476 ± 0.021	4.917ArgAsp: 4.917 ± 0.065	4.332ArgGlu: 4.332 ± 0.063	2.787ArgPhe: 2.787 ± 0.055	5.324ArgGly: 5.324 ± 0.066	1.789ArgHis: 1.789 ± 0.043	3.87ArgIle: 3.87 ± 0.061	1.912ArgLys: 1.912 ± 0.04	8.283ArgLeu: 8.283 ± 0.096	2.071ArgMet: 2.071 ± 0.042	1.714ArgAsn: 1.714 ± 0.041	3.87ArgPro: 3.87 ± 0.062	2.421ArgGln: 2.421 ± 0.046	6.378ArgArg: 6.378 ± 0.099	3.577ArgSer: 3.577 ± 0.058	3.677ArgThr: 3.677 ± 0.055	5.235ArgVal: 5.235 ± 0.063	0.985ArgTrp: 0.985 ± 0.029	1.588ArgTyr: 1.588 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.914SerAla: 5.914 ± 0.068	0.39SerCys: 0.39 ± 0.018	3.514SerAsp: 3.514 ± 0.054	3.177SerGlu: 3.177 ± 0.054	2.11SerPhe: 2.11 ± 0.047	5.486SerGly: 5.486 ± 0.066	1.037SerHis: 1.037 ± 0.025	2.227SerIle: 2.227 ± 0.046	1.136SerLys: 1.136 ± 0.032	4.952SerLeu: 4.952 ± 0.07	1.244SerMet: 1.244 ± 0.032	1.17SerAsn: 1.17 ± 0.031	2.492SerPro: 2.492 ± 0.045	1.5SerGln: 1.5 ± 0.034	3.655SerArg: 3.655 ± 0.057	2.442SerSer: 2.442 ± 0.058	2.467SerThr: 2.467 ± 0.049	3.939SerVal: 3.939 ± 0.061	0.698SerTrp: 0.698 ± 0.024	1.208SerTyr: 1.208 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	6.662ThrAla: 6.662 ± 0.079	0.494ThrCys: 0.494 ± 0.023	3.429ThrAsp: 3.429 ± 0.059	3.305ThrGlu: 3.305 ± 0.057	2.033ThrPhe: 2.033 ± 0.042	5.716ThrGly: 5.716 ± 0.074	1.087ThrHis: 1.087 ± 0.031	2.606ThrIle: 2.606 ± 0.052	1.121ThrLys: 1.121 ± 0.032	6.361ThrLeu: 6.361 ± 0.075	1.324ThrMet: 1.324 ± 0.031	1.17ThrAsn: 1.17 ± 0.034	3.512ThrPro: 3.512 ± 0.063	1.438ThrGln: 1.438 ± 0.034	3.745ThrArg: 3.745 ± 0.06	2.573ThrSer: 2.573 ± 0.047	2.811ThrThr: 2.811 ± 0.053	4.459ThrVal: 4.459 ± 0.065	0.756ThrTrp: 0.756 ± 0.025	1.209ThrTyr: 1.209 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	9.423ValAla: 9.423 ± 0.098	0.698ValCys: 0.698 ± 0.022	4.184ValAsp: 4.184 ± 0.062	4.772ValGlu: 4.772 ± 0.059	2.889ValPhe: 2.889 ± 0.047	5.805ValGly: 5.805 ± 0.068	1.367ValHis: 1.367 ± 0.036	3.855ValIle: 3.855 ± 0.061	1.676ValLys: 1.676 ± 0.041	7.637ValLeu: 7.637 ± 0.097	2.057ValMet: 2.057 ± 0.041	1.773ValAsn: 1.773 ± 0.037	3.924ValPro: 3.924 ± 0.064	1.985ValGln: 1.985 ± 0.041	4.944ValArg: 4.944 ± 0.07	4.474ValSer: 4.474 ± 0.064	5.04ValThr: 5.04 ± 0.062	5.803ValVal: 5.803 ± 0.073	0.982ValTrp: 0.982 ± 0.03	1.5ValTyr: 1.5 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.4TrpAla: 1.4 ± 0.034	0.145TrpCys: 0.145 ± 0.011	0.751TrpAsp: 0.751 ± 0.027	0.66TrpGlu: 0.66 ± 0.02	0.537TrpPhe: 0.537 ± 0.021	1.068TrpGly: 1.068 ± 0.033	0.357TrpHis: 0.357 ± 0.018	0.705TrpIle: 0.705 ± 0.019	0.358TrpLys: 0.358 ± 0.016	1.674TrpLeu: 1.674 ± 0.039	0.383TrpMet: 0.383 ± 0.017	0.378TrpAsn: 0.378 ± 0.019	0.732TrpPro: 0.732 ± 0.025	0.605TrpGln: 0.605 ± 0.022	1.265TrpArg: 1.265 ± 0.032	0.88TrpSer: 0.88 ± 0.028	0.877TrpThr: 0.877 ± 0.028	0.872TrpVal: 0.872 ± 0.025	0.244TrpTrp: 0.244 ± 0.015	0.251TrpTyr: 0.251 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.443TyrAla: 2.443 ± 0.049	0.229TyrCys: 0.229 ± 0.013	1.612TyrAsp: 1.612 ± 0.039	1.306TyrGlu: 1.306 ± 0.037	0.87TyrPhe: 0.87 ± 0.029	2.082TyrGly: 2.082 ± 0.049	0.476TyrHis: 0.476 ± 0.02	0.78TyrIle: 0.78 ± 0.03	0.425TyrLys: 0.425 ± 0.018	2.174TyrLeu: 2.174 ± 0.039	0.436TyrMet: 0.436 ± 0.02	0.531TyrAsn: 0.531 ± 0.025	1.003TyrPro: 1.003 ± 0.033	0.595TyrGln: 0.595 ± 0.025	1.615TyrArg: 1.615 ± 0.039	1.077TyrSer: 1.077 ± 0.034	1.04TyrThr: 1.04 ± 0.035	1.493TyrVal: 1.493 ± 0.034	0.362TyrTrp: 0.362 ± 0.018	0.563TyrTyr: 0.563 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4061 proteins (1273032 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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