Amino acid dipepetide frequency for Myroides guanonis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.654AlaAla: 3.654 ± 0.087	0.608AlaCys: 0.608 ± 0.028	2.915AlaAsp: 2.915 ± 0.056	3.419AlaGlu: 3.419 ± 0.067	3.273AlaPhe: 3.273 ± 0.063	3.747AlaGly: 3.747 ± 0.078	1.005AlaHis: 1.005 ± 0.033	5.252AlaIle: 5.252 ± 0.093	4.225AlaLys: 4.225 ± 0.088	6.302AlaLeu: 6.302 ± 0.085	1.502AlaMet: 1.502 ± 0.051	3.052AlaAsn: 3.052 ± 0.059	1.796AlaPro: 1.796 ± 0.058	2.185AlaGln: 2.185 ± 0.055	1.883AlaArg: 1.883 ± 0.048	3.99AlaSer: 3.99 ± 0.071	3.591AlaThr: 3.591 ± 0.085	3.917AlaVal: 3.917 ± 0.069	0.614AlaTrp: 0.614 ± 0.032	2.336AlaTyr: 2.336 ± 0.066	0.0AlaXaa: 0.0 ± 0.0
Cys	0.459CysAla: 0.459 ± 0.025	0.096CysCys: 0.096 ± 0.009	0.421CysAsp: 0.421 ± 0.025	0.513CysGlu: 0.513 ± 0.03	0.463CysPhe: 0.463 ± 0.025	0.678CysGly: 0.678 ± 0.055	0.134CysHis: 0.134 ± 0.013	0.616CysIle: 0.616 ± 0.023	0.491CysLys: 0.491 ± 0.024	0.659CysLeu: 0.659 ± 0.026	0.172CysMet: 0.172 ± 0.013	0.433CysAsn: 0.433 ± 0.022	0.37CysPro: 0.37 ± 0.025	0.19CysGln: 0.19 ± 0.015	0.21CysArg: 0.21 ± 0.014	0.641CysSer: 0.641 ± 0.031	0.453CysThr: 0.453 ± 0.023	0.493CysVal: 0.493 ± 0.024	0.136CysTrp: 0.136 ± 0.021	0.312CysTyr: 0.312 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.163AspAla: 3.163 ± 0.06	0.459AspCys: 0.459 ± 0.024	2.492AspAsp: 2.492 ± 0.055	3.732AspGlu: 3.732 ± 0.072	3.627AspPhe: 3.627 ± 0.072	3.455AspGly: 3.455 ± 0.073	0.826AspHis: 0.826 ± 0.034	4.295AspIle: 4.295 ± 0.059	4.134AspLys: 4.134 ± 0.075	5.596AspLeu: 5.596 ± 0.085	1.163AspMet: 1.163 ± 0.037	2.956AspAsn: 2.956 ± 0.061	1.504AspPro: 1.504 ± 0.039	1.46AspGln: 1.46 ± 0.041	1.972AspArg: 1.972 ± 0.049	3.612AspSer: 3.612 ± 0.075	2.535AspThr: 2.535 ± 0.055	3.697AspVal: 3.697 ± 0.065	0.773AspTrp: 0.773 ± 0.035	2.871AspTyr: 2.871 ± 0.063	0.0AspXaa: 0.0 ± 0.0
Glu	4.128GluAla: 4.128 ± 0.071	0.4GluCys: 0.4 ± 0.025	3.512GluAsp: 3.512 ± 0.061	5.512GluGlu: 5.512 ± 0.094	3.194GluPhe: 3.194 ± 0.065	4.071GluGly: 4.071 ± 0.08	1.115GluHis: 1.115 ± 0.037	5.68GluIle: 5.68 ± 0.092	5.837GluLys: 5.837 ± 0.105	6.725GluLeu: 6.725 ± 0.102	1.642GluMet: 1.642 ± 0.047	4.527GluAsn: 4.527 ± 0.08	1.553GluPro: 1.553 ± 0.039	2.504GluGln: 2.504 ± 0.06	2.751GluArg: 2.751 ± 0.062	3.915GluSer: 3.915 ± 0.065	3.509GluThr: 3.509 ± 0.062	4.891GluVal: 4.891 ± 0.086	0.688GluTrp: 0.688 ± 0.031	2.694GluTyr: 2.694 ± 0.06	0.0GluXaa: 0.0 ± 0.0
Phe	2.779PheAla: 2.779 ± 0.059	0.461PheCys: 0.461 ± 0.025	3.286PheAsp: 3.286 ± 0.064	3.784PheGlu: 3.784 ± 0.064	2.741PhePhe: 2.741 ± 0.071	3.553PheGly: 3.553 ± 0.064	0.84PheHis: 0.84 ± 0.033	4.091PheIle: 4.091 ± 0.084	3.925PheLys: 3.925 ± 0.067	4.858PheLeu: 4.858 ± 0.098	1.175PheMet: 1.175 ± 0.036	3.279PheAsn: 3.279 ± 0.068	1.64PhePro: 1.64 ± 0.044	1.665PheGln: 1.665 ± 0.04	1.541PheArg: 1.541 ± 0.043	3.947PheSer: 3.947 ± 0.067	2.988PheThr: 2.988 ± 0.065	3.348PheVal: 3.348 ± 0.059	0.567PheTrp: 0.567 ± 0.028	2.259PheTyr: 2.259 ± 0.057	0.0PheXaa: 0.0 ± 0.0
Gly	4.149GlyAla: 4.149 ± 0.079	0.577GlyCys: 0.577 ± 0.03	3.294GlyAsp: 3.294 ± 0.074	3.588GlyGlu: 3.588 ± 0.07	3.613GlyPhe: 3.613 ± 0.063	4.5GlyGly: 4.5 ± 0.086	1.047GlyHis: 1.047 ± 0.036	5.318GlyIle: 5.318 ± 0.079	4.764GlyLys: 4.764 ± 0.074	5.769GlyLeu: 5.769 ± 0.099	1.684GlyMet: 1.684 ± 0.046	3.448GlyAsn: 3.448 ± 0.084	1.297GlyPro: 1.297 ± 0.044	1.725GlyGln: 1.725 ± 0.05	2.011GlyArg: 2.011 ± 0.058	4.144GlySer: 4.144 ± 0.086	3.977GlyThr: 3.977 ± 0.08	5.038GlyVal: 5.038 ± 0.083	0.676GlyTrp: 0.676 ± 0.029	2.697GlyTyr: 2.697 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	0.931HisAla: 0.931 ± 0.037	0.15HisCys: 0.15 ± 0.013	0.832HisAsp: 0.832 ± 0.024	0.931HisGlu: 0.931 ± 0.035	1.135HisPhe: 1.135 ± 0.036	1.014HisGly: 1.014 ± 0.034	0.399HisHis: 0.399 ± 0.021	1.449HisIle: 1.449 ± 0.042	1.094HisLys: 1.094 ± 0.033	1.828HisLeu: 1.828 ± 0.051	0.301HisMet: 0.301 ± 0.017	0.941HisAsn: 0.941 ± 0.034	0.784HisPro: 0.784 ± 0.032	0.685HisGln: 0.685 ± 0.031	0.64HisArg: 0.64 ± 0.027	1.174HisSer: 1.174 ± 0.036	0.951HisThr: 0.951 ± 0.033	0.891HisVal: 0.891 ± 0.033	0.19HisTrp: 0.19 ± 0.015	0.879HisTyr: 0.879 ± 0.035	0.0HisXaa: 0.0 ± 0.0
Ile	5.477IleAla: 5.477 ± 0.096	0.645IleCys: 0.645 ± 0.028	4.944IleAsp: 4.944 ± 0.075	6.145IleGlu: 6.145 ± 0.101	3.357IlePhe: 3.357 ± 0.074	5.414IleGly: 5.414 ± 0.08	1.539IleHis: 1.539 ± 0.041	5.841IleIle: 5.841 ± 0.111	5.602IleLys: 5.602 ± 0.089	7.245IleLeu: 7.245 ± 0.113	1.372IleMet: 1.372 ± 0.039	4.523IleAsn: 4.523 ± 0.07	3.195IlePro: 3.195 ± 0.062	2.882IleGln: 2.882 ± 0.058	2.757IleArg: 2.757 ± 0.058	5.907IleSer: 5.907 ± 0.083	4.637IleThr: 4.637 ± 0.079	5.168IleVal: 5.168 ± 0.079	0.714IleTrp: 0.714 ± 0.029	2.977IleTyr: 2.977 ± 0.06	0.0IleXaa: 0.0 ± 0.0
Lys	4.606LysAla: 4.606 ± 0.087	0.34LysCys: 0.34 ± 0.021	4.642LysAsp: 4.642 ± 0.079	6.587LysGlu: 6.587 ± 0.101	2.703LysPhe: 2.703 ± 0.051	4.733LysGly: 4.733 ± 0.081	1.309LysHis: 1.309 ± 0.041	5.824LysIle: 5.824 ± 0.099	6.296LysLys: 6.296 ± 0.106	6.172LysLeu: 6.172 ± 0.102	2.085LysMet: 2.085 ± 0.048	5.155LysAsn: 5.155 ± 0.093	2.276LysPro: 2.276 ± 0.048	2.623LysGln: 2.623 ± 0.06	2.851LysArg: 2.851 ± 0.053	4.637LysSer: 4.637 ± 0.074	4.522LysThr: 4.522 ± 0.064	4.9LysVal: 4.9 ± 0.078	0.802LysTrp: 0.802 ± 0.036	3.055LysTyr: 3.055 ± 0.064	0.0LysXaa: 0.0 ± 0.0
Leu	5.6LeuAla: 5.6 ± 0.088	0.824LeuCys: 0.824 ± 0.031	5.287LeuAsp: 5.287 ± 0.094	6.751LeuGlu: 6.751 ± 0.1	5.109LeuPhe: 5.109 ± 0.087	6.036LeuGly: 6.036 ± 0.099	1.585LeuHis: 1.585 ± 0.043	7.272LeuIle: 7.272 ± 0.112	7.714LeuLys: 7.714 ± 0.115	9.334LeuLeu: 9.334 ± 0.145	2.293LeuMet: 2.293 ± 0.062	5.834LeuAsn: 5.834 ± 0.087	3.555LeuPro: 3.555 ± 0.062	3.273LeuGln: 3.273 ± 0.064	3.185LeuArg: 3.185 ± 0.067	6.97LeuSer: 6.97 ± 0.106	4.822LeuThr: 4.822 ± 0.071	5.636LeuVal: 5.636 ± 0.092	0.789LeuTrp: 0.789 ± 0.031	3.507LeuTyr: 3.507 ± 0.064	0.0LeuXaa: 0.0 ± 0.0
Met	1.486MetAla: 1.486 ± 0.044	0.148MetCys: 0.148 ± 0.013	1.208MetAsp: 1.208 ± 0.034	1.541MetGlu: 1.541 ± 0.041	1.032MetPhe: 1.032 ± 0.038	1.489MetGly: 1.489 ± 0.046	0.38MetHis: 0.38 ± 0.022	1.673MetIle: 1.673 ± 0.052	2.188MetLys: 2.188 ± 0.053	2.032MetLeu: 2.032 ± 0.043	0.57MetMet: 0.57 ± 0.026	1.429MetAsn: 1.429 ± 0.044	0.814MetPro: 0.814 ± 0.03	0.791MetGln: 0.791 ± 0.03	0.988MetArg: 0.988 ± 0.037	1.57MetSer: 1.57 ± 0.042	1.116MetThr: 1.116 ± 0.033	1.332MetVal: 1.332 ± 0.043	0.176MetTrp: 0.176 ± 0.014	0.831MetTyr: 0.831 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.465AsnAla: 3.465 ± 0.061	0.511AsnCys: 0.511 ± 0.032	3.042AsnAsp: 3.042 ± 0.063	3.812AsnGlu: 3.812 ± 0.069	2.898AsnPhe: 2.898 ± 0.067	3.73AsnGly: 3.73 ± 0.072	1.129AsnHis: 1.129 ± 0.037	4.688AsnIle: 4.688 ± 0.088	4.492AsnLys: 4.492 ± 0.077	5.409AsnLeu: 5.409 ± 0.08	1.206AsnMet: 1.206 ± 0.038	3.733AsnAsn: 3.733 ± 0.085	2.577AsnPro: 2.577 ± 0.052	2.367AsnGln: 2.367 ± 0.062	2.277AsnArg: 2.277 ± 0.053	4.158AsnSer: 4.158 ± 0.066	3.572AsnThr: 3.572 ± 0.073	3.478AsnVal: 3.478 ± 0.077	0.74AsnTrp: 0.74 ± 0.03	2.74AsnTyr: 2.74 ± 0.065	0.0AsnXaa: 0.0 ± 0.0
Pro	1.652ProAla: 1.652 ± 0.053	0.212ProCys: 0.212 ± 0.015	1.708ProAsp: 1.708 ± 0.044	2.425ProGlu: 2.425 ± 0.054	1.977ProPhe: 1.977 ± 0.049	1.767ProGly: 1.767 ± 0.046	0.582ProHis: 0.582 ± 0.023	3.05ProIle: 3.05 ± 0.056	2.349ProLys: 2.349 ± 0.048	2.972ProLeu: 2.972 ± 0.061	0.779ProMet: 0.779 ± 0.029	2.284ProAsn: 2.284 ± 0.053	0.731ProPro: 0.731 ± 0.031	1.041ProGln: 1.041 ± 0.036	0.87ProArg: 0.87 ± 0.032	2.121ProSer: 2.121 ± 0.043	2.041ProThr: 2.041 ± 0.056	2.033ProVal: 2.033 ± 0.056	0.296ProTrp: 0.296 ± 0.02	1.367ProTyr: 1.367 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.022GlnAla: 2.022 ± 0.056	0.183GlnCys: 0.183 ± 0.014	1.686GlnAsp: 1.686 ± 0.038	2.448GlnGlu: 2.448 ± 0.054	1.693GlnPhe: 1.693 ± 0.043	1.81GlnGly: 1.81 ± 0.047	0.624GlnHis: 0.624 ± 0.024	2.714GlnIle: 2.714 ± 0.055	2.781GlnLys: 2.781 ± 0.062	3.499GlnLeu: 3.499 ± 0.071	0.781GlnMet: 0.781 ± 0.023	2.157GlnAsn: 2.157 ± 0.05	0.964GlnPro: 0.964 ± 0.033	1.343GlnGln: 1.343 ± 0.048	1.231GlnArg: 1.231 ± 0.041	2.134GlnSer: 2.134 ± 0.054	1.85GlnThr: 1.85 ± 0.05	2.071GlnVal: 2.071 ± 0.048	0.387GlnTrp: 0.387 ± 0.021	1.335GlnTyr: 1.335 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	1.877ArgAla: 1.877 ± 0.048	0.2ArgCys: 0.2 ± 0.015	1.736ArgAsp: 1.736 ± 0.045	2.303ArgGlu: 2.303 ± 0.062	1.99ArgPhe: 1.99 ± 0.053	1.892ArgGly: 1.892 ± 0.059	0.545ArgHis: 0.545 ± 0.025	3.112ArgIle: 3.112 ± 0.058	2.695ArgLys: 2.695 ± 0.054	3.388ArgLeu: 3.388 ± 0.072	1.013ArgMet: 1.013 ± 0.032	2.04ArgAsn: 2.04 ± 0.048	0.949ArgPro: 0.949 ± 0.035	1.038ArgGln: 1.038 ± 0.037	1.233ArgArg: 1.233 ± 0.046	1.945ArgSer: 1.945 ± 0.047	1.93ArgThr: 1.93 ± 0.045	2.355ArgVal: 2.355 ± 0.046	0.403ArgTrp: 0.403 ± 0.019	1.588ArgTyr: 1.588 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	3.361SerAla: 3.361 ± 0.058	0.714SerCys: 0.714 ± 0.033	3.58SerAsp: 3.58 ± 0.074	4.162SerGlu: 4.162 ± 0.071	4.301SerPhe: 4.301 ± 0.069	4.586SerGly: 4.586 ± 0.08	1.095SerHis: 1.095 ± 0.033	5.868SerIle: 5.868 ± 0.098	5.307SerLys: 5.307 ± 0.084	6.671SerLeu: 6.671 ± 0.084	1.504SerMet: 1.504 ± 0.04	4.23SerAsn: 4.23 ± 0.079	2.1SerPro: 2.1 ± 0.052	2.148SerGln: 2.148 ± 0.046	2.069SerArg: 2.069 ± 0.054	4.899SerSer: 4.899 ± 0.092	3.618SerThr: 3.618 ± 0.073	4.081SerVal: 4.081 ± 0.074	0.71SerTrp: 0.71 ± 0.029	3.066SerTyr: 3.066 ± 0.068	0.0SerXaa: 0.0 ± 0.0
Thr	3.493ThrAla: 3.493 ± 0.075	0.377ThrCys: 0.377 ± 0.025	3.03ThrAsp: 3.03 ± 0.066	3.379ThrGlu: 3.379 ± 0.065	2.738ThrPhe: 2.738 ± 0.061	3.654ThrGly: 3.654 ± 0.071	1.0ThrHis: 1.0 ± 0.034	4.939ThrIle: 4.939 ± 0.073	3.76ThrLys: 3.76 ± 0.062	5.441ThrLeu: 5.441 ± 0.086	1.041ThrMet: 1.041 ± 0.036	3.216ThrAsn: 3.216 ± 0.071	2.436ThrPro: 2.436 ± 0.053	1.956ThrGln: 1.956 ± 0.048	1.569ThrArg: 1.569 ± 0.043	3.979ThrSer: 3.979 ± 0.079	3.565ThrThr: 3.565 ± 0.093	3.81ThrVal: 3.81 ± 0.089	0.505ThrTrp: 0.505 ± 0.025	2.319ThrTyr: 2.319 ± 0.064	0.0ThrXaa: 0.0 ± 0.0
Val	4.04ValAla: 4.04 ± 0.077	0.595ValCys: 0.595 ± 0.026	3.79ValAsp: 3.79 ± 0.066	4.375ValGlu: 4.375 ± 0.077	3.854ValPhe: 3.854 ± 0.072	4.065ValGly: 4.065 ± 0.082	0.958ValHis: 0.958 ± 0.035	4.946ValIle: 4.946 ± 0.085	4.515ValLys: 4.515 ± 0.079	6.521ValLeu: 6.521 ± 0.098	1.407ValMet: 1.407 ± 0.037	3.563ValAsn: 3.563 ± 0.065	2.147ValPro: 2.147 ± 0.049	1.943ValGln: 1.943 ± 0.046	2.143ValArg: 2.143 ± 0.05	4.783ValSer: 4.783 ± 0.081	3.495ValThr: 3.495 ± 0.08	4.63ValVal: 4.63 ± 0.095	0.599ValTrp: 0.599 ± 0.029	2.513ValTyr: 2.513 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	0.565TrpAla: 0.565 ± 0.024	0.097TrpCys: 0.097 ± 0.011	0.568TrpAsp: 0.568 ± 0.026	0.777TrpGlu: 0.777 ± 0.04	0.523TrpPhe: 0.523 ± 0.025	0.604TrpGly: 0.604 ± 0.025	0.251TrpHis: 0.251 ± 0.019	0.756TrpIle: 0.756 ± 0.03	0.791TrpLys: 0.791 ± 0.032	0.999TrpLeu: 0.999 ± 0.037	0.313TrpMet: 0.313 ± 0.018	0.695TrpAsn: 0.695 ± 0.027	0.182TrpPro: 0.182 ± 0.013	0.384TrpGln: 0.384 ± 0.021	0.358TrpArg: 0.358 ± 0.02	0.652TrpSer: 0.652 ± 0.031	0.645TrpThr: 0.645 ± 0.036	0.653TrpVal: 0.653 ± 0.029	0.101TrpTrp: 0.101 ± 0.012	0.417TrpTyr: 0.417 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.358TyrAla: 2.358 ± 0.046	0.342TyrCys: 0.342 ± 0.018	2.35TyrAsp: 2.35 ± 0.059	2.663TyrGlu: 2.663 ± 0.064	2.509TyrPhe: 2.509 ± 0.057	2.516TyrGly: 2.516 ± 0.052	0.837TyrHis: 0.837 ± 0.028	2.958TyrIle: 2.958 ± 0.06	3.162TyrLys: 3.162 ± 0.062	3.959TyrLeu: 3.959 ± 0.072	0.789TyrMet: 0.789 ± 0.025	2.528TyrAsn: 2.528 ± 0.057	1.388TyrPro: 1.388 ± 0.044	1.509TyrGln: 1.509 ± 0.045	1.689TyrArg: 1.689 ± 0.048	2.893TyrSer: 2.893 ± 0.061	2.387TyrThr: 2.387 ± 0.066	2.463TyrVal: 2.463 ± 0.063	0.465TyrTrp: 0.465 ± 0.023	2.268TyrTyr: 2.268 ± 0.065	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2674 proteins (919248 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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