Amino acid dipepetide frequency for Harryflintia acetispora

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.188AlaAla: 11.188 ± 0.161	1.475AlaCys: 1.475 ± 0.046	4.471AlaAsp: 4.471 ± 0.088	4.783AlaGlu: 4.783 ± 0.088	3.368AlaPhe: 3.368 ± 0.074	8.664AlaGly: 8.664 ± 0.124	1.503AlaHis: 1.503 ± 0.041	4.994AlaIle: 4.994 ± 0.075	4.242AlaLys: 4.242 ± 0.08	10.719AlaLeu: 10.719 ± 0.157	2.451AlaMet: 2.451 ± 0.061	2.267AlaAsn: 2.267 ± 0.058	3.772AlaPro: 3.772 ± 0.08	3.832AlaGln: 3.832 ± 0.081	4.918AlaArg: 4.918 ± 0.092	4.675AlaSer: 4.675 ± 0.104	3.672AlaThr: 3.672 ± 0.08	7.376AlaVal: 7.376 ± 0.096	0.699AlaTrp: 0.699 ± 0.029	2.501AlaTyr: 2.501 ± 0.055	0.002AlaXaa: 0.002 ± 0.001
Cys	1.839CysAla: 1.839 ± 0.059	0.419CysCys: 0.419 ± 0.026	1.011CysAsp: 1.011 ± 0.043	1.214CysGlu: 1.214 ± 0.043	0.662CysPhe: 0.662 ± 0.027	2.027CysGly: 2.027 ± 0.064	0.325CysHis: 0.325 ± 0.022	0.722CysIle: 0.722 ± 0.032	0.76CysLys: 0.76 ± 0.033	1.334CysLeu: 1.334 ± 0.046	0.397CysMet: 0.397 ± 0.023	0.491CysAsn: 0.491 ± 0.022	0.798CysPro: 0.798 ± 0.038	0.507CysGln: 0.507 ± 0.027	1.105CysArg: 1.105 ± 0.037	1.0CysSer: 1.0 ± 0.035	0.816CysThr: 0.816 ± 0.034	1.097CysVal: 1.097 ± 0.033	0.145CysTrp: 0.145 ± 0.014	0.692CysTyr: 0.692 ± 0.035	0.0CysXaa: 0.0 ± 0.0
Asp	4.029AspAla: 4.029 ± 0.075	0.9AspCys: 0.9 ± 0.038	2.434AspAsp: 2.434 ± 0.067	4.411AspGlu: 4.411 ± 0.085	2.548AspPhe: 2.548 ± 0.06	4.785AspGly: 4.785 ± 0.108	0.83AspHis: 0.83 ± 0.034	3.541AspIle: 3.541 ± 0.067	2.479AspLys: 2.479 ± 0.065	4.629AspLeu: 4.629 ± 0.075	1.428AspMet: 1.428 ± 0.05	1.628AspAsn: 1.628 ± 0.046	2.628AspPro: 2.628 ± 0.062	1.265AspGln: 1.265 ± 0.037	2.721AspArg: 2.721 ± 0.057	2.797AspSer: 2.797 ± 0.069	2.679AspThr: 2.679 ± 0.061	3.438AspVal: 3.438 ± 0.069	0.617AspTrp: 0.617 ± 0.03	2.513AspTyr: 2.513 ± 0.06	0.0AspXaa: 0.0 ± 0.0
Glu	6.125GluAla: 6.125 ± 0.086	0.848GluCys: 0.848 ± 0.036	3.574GluAsp: 3.574 ± 0.072	5.855GluGlu: 5.855 ± 0.112	2.093GluPhe: 2.093 ± 0.049	5.252GluGly: 5.252 ± 0.09	1.403GluHis: 1.403 ± 0.045	4.339GluIle: 4.339 ± 0.085	3.738GluLys: 3.738 ± 0.077	7.033GluLeu: 7.033 ± 0.102	2.045GluMet: 2.045 ± 0.054	2.85GluAsn: 2.85 ± 0.06	2.324GluPro: 2.324 ± 0.054	3.061GluGln: 3.061 ± 0.072	5.418GluArg: 5.418 ± 0.123	3.398GluSer: 3.398 ± 0.064	3.061GluThr: 3.061 ± 0.058	4.172GluVal: 4.172 ± 0.081	0.575GluTrp: 0.575 ± 0.026	2.58GluTyr: 2.58 ± 0.061	0.0GluXaa: 0.0 ± 0.0
Phe	3.379PheAla: 3.379 ± 0.073	0.9PheCys: 0.9 ± 0.031	2.351PheAsp: 2.351 ± 0.053	2.667PheGlu: 2.667 ± 0.057	1.774PhePhe: 1.774 ± 0.057	3.373PheGly: 3.373 ± 0.063	0.729PheHis: 0.729 ± 0.029	2.133PheIle: 2.133 ± 0.056	1.544PheLys: 1.544 ± 0.048	4.105PheLeu: 4.105 ± 0.096	0.945PheMet: 0.945 ± 0.032	1.108PheAsn: 1.108 ± 0.041	1.572PhePro: 1.572 ± 0.041	1.06PheGln: 1.06 ± 0.033	1.68PheArg: 1.68 ± 0.046	3.044PheSer: 3.044 ± 0.053	2.355PheThr: 2.355 ± 0.048	2.664PheVal: 2.664 ± 0.054	0.514PheTrp: 0.514 ± 0.024	1.556PheTyr: 1.556 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	7.491GlyAla: 7.491 ± 0.101	1.646GlyCys: 1.646 ± 0.054	4.019GlyAsp: 4.019 ± 0.074	6.72GlyGlu: 6.72 ± 0.104	3.291GlyPhe: 3.291 ± 0.061	7.286GlyGly: 7.286 ± 0.112	1.382GlyHis: 1.382 ± 0.039	5.141GlyIle: 5.141 ± 0.084	4.471GlyLys: 4.471 ± 0.084	7.599GlyLeu: 7.599 ± 0.111	2.57GlyMet: 2.57 ± 0.061	2.624GlyAsn: 2.624 ± 0.066	1.995GlyPro: 1.995 ± 0.047	2.623GlyGln: 2.623 ± 0.058	4.829GlyArg: 4.829 ± 0.072	4.949GlySer: 4.949 ± 0.098	4.274GlyThr: 4.274 ± 0.09	6.214GlyVal: 6.214 ± 0.091	0.855GlyTrp: 0.855 ± 0.035	3.386GlyTyr: 3.386 ± 0.063	0.0GlyXaa: 0.0 ± 0.0
His	1.451HisAla: 1.451 ± 0.043	0.322HisCys: 0.322 ± 0.02	0.838HisAsp: 0.838 ± 0.031	1.09HisGlu: 1.09 ± 0.039	0.834HisPhe: 0.834 ± 0.029	1.388HisGly: 1.388 ± 0.045	0.376HisHis: 0.376 ± 0.022	1.111HisIle: 1.111 ± 0.036	0.788HisLys: 0.788 ± 0.034	1.684HisLeu: 1.684 ± 0.048	0.442HisMet: 0.442 ± 0.02	0.635HisAsn: 0.635 ± 0.026	1.025HisPro: 1.025 ± 0.032	0.469HisGln: 0.469 ± 0.024	1.003HisArg: 1.003 ± 0.038	0.995HisSer: 0.995 ± 0.036	0.987HisThr: 0.987 ± 0.036	0.958HisVal: 0.958 ± 0.032	0.171HisTrp: 0.171 ± 0.014	0.7HisTyr: 0.7 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.477IleAla: 5.477 ± 0.098	1.006IleCys: 1.006 ± 0.036	3.434IleAsp: 3.434 ± 0.07	4.1IleGlu: 4.1 ± 0.068	2.196IlePhe: 2.196 ± 0.058	4.765IleGly: 4.765 ± 0.079	0.956IleHis: 0.956 ± 0.034	3.187IleIle: 3.187 ± 0.075	2.713IleLys: 2.713 ± 0.06	5.81IleLeu: 5.81 ± 0.114	1.361IleMet: 1.361 ± 0.046	1.898IleAsn: 1.898 ± 0.048	2.968IlePro: 2.968 ± 0.061	1.52IleGln: 1.52 ± 0.037	3.15IleArg: 3.15 ± 0.062	3.851IleSer: 3.851 ± 0.061	3.542IleThr: 3.542 ± 0.083	4.173IleVal: 4.173 ± 0.069	0.477IleTrp: 0.477 ± 0.024	1.913IleTyr: 1.913 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.184LysAla: 4.184 ± 0.079	0.489LysCys: 0.489 ± 0.024	2.427LysAsp: 2.427 ± 0.062	4.027LysGlu: 4.027 ± 0.08	1.296LysPhe: 1.296 ± 0.044	3.491LysGly: 3.491 ± 0.063	0.655LysHis: 0.655 ± 0.028	3.056LysIle: 3.056 ± 0.061	3.362LysLys: 3.362 ± 0.085	4.442LysLeu: 4.442 ± 0.08	1.424LysMet: 1.424 ± 0.042	2.109LysAsn: 2.109 ± 0.05	1.788LysPro: 1.788 ± 0.052	1.54LysGln: 1.54 ± 0.046	2.872LysArg: 2.872 ± 0.06	2.498LysSer: 2.498 ± 0.056	2.659LysThr: 2.659 ± 0.062	3.244LysVal: 3.244 ± 0.079	0.4LysTrp: 0.4 ± 0.021	1.671LysTyr: 1.671 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	8.797LeuAla: 8.797 ± 0.113	2.695LeuCys: 2.695 ± 0.078	5.357LeuAsp: 5.357 ± 0.086	6.215LeuGlu: 6.215 ± 0.108	3.989LeuPhe: 3.989 ± 0.086	8.111LeuGly: 8.111 ± 0.13	1.916LeuHis: 1.916 ± 0.051	5.774LeuIle: 5.774 ± 0.11	3.982LeuLys: 3.982 ± 0.069	11.499LeuLeu: 11.499 ± 0.198	2.488LeuMet: 2.488 ± 0.057	2.656LeuAsn: 2.656 ± 0.057	5.265LeuPro: 5.265 ± 0.078	3.576LeuGln: 3.576 ± 0.077	6.792LeuArg: 6.792 ± 0.106	7.715LeuSer: 7.715 ± 0.11	5.079LeuThr: 5.079 ± 0.081	6.006LeuVal: 6.006 ± 0.094	0.931LeuTrp: 0.931 ± 0.038	3.451LeuTyr: 3.451 ± 0.065	0.0LeuXaa: 0.0 ± 0.0
Met	2.411MetAla: 2.411 ± 0.056	0.323MetCys: 0.323 ± 0.022	1.487MetAsp: 1.487 ± 0.045	2.009MetGlu: 2.009 ± 0.054	0.9MetPhe: 0.9 ± 0.041	2.149MetGly: 2.149 ± 0.054	0.379MetHis: 0.379 ± 0.022	1.664MetIle: 1.664 ± 0.047	1.855MetLys: 1.855 ± 0.052	2.723MetLeu: 2.723 ± 0.064	0.728MetMet: 0.728 ± 0.033	1.009MetAsn: 1.009 ± 0.034	1.083MetPro: 1.083 ± 0.037	0.879MetGln: 0.879 ± 0.035	1.38MetArg: 1.38 ± 0.038	1.612MetSer: 1.612 ± 0.045	1.48MetThr: 1.48 ± 0.043	1.864MetVal: 1.864 ± 0.049	0.169MetTrp: 0.169 ± 0.013	0.61MetTyr: 0.61 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	2.815AsnAla: 2.815 ± 0.068	0.534AsnCys: 0.534 ± 0.028	1.562AsnAsp: 1.562 ± 0.046	1.849AsnGlu: 1.849 ± 0.048	1.276AsnPhe: 1.276 ± 0.044	2.56AsnGly: 2.56 ± 0.057	0.589AsnHis: 0.589 ± 0.023	2.218AsnIle: 2.218 ± 0.051	1.332AsnLys: 1.332 ± 0.045	3.272AsnLeu: 3.272 ± 0.06	0.868AsnMet: 0.868 ± 0.032	1.072AsnAsn: 1.072 ± 0.045	1.929AsnPro: 1.929 ± 0.05	0.902AsnGln: 0.902 ± 0.03	1.742AsnArg: 1.742 ± 0.045	1.673AsnSer: 1.673 ± 0.051	1.83AsnThr: 1.83 ± 0.062	2.177AsnVal: 2.177 ± 0.061	0.326AsnTrp: 0.326 ± 0.022	1.19AsnTyr: 1.19 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	4.217ProAla: 4.217 ± 0.082	0.608ProCys: 0.608 ± 0.028	2.73ProAsp: 2.73 ± 0.059	3.318ProGlu: 3.318 ± 0.078	1.874ProPhe: 1.874 ± 0.047	3.533ProGly: 3.533 ± 0.062	0.752ProHis: 0.752 ± 0.028	2.183ProIle: 2.183 ± 0.049	1.957ProLys: 1.957 ± 0.046	3.893ProLeu: 3.893 ± 0.071	0.986ProMet: 0.986 ± 0.033	1.201ProAsn: 1.201 ± 0.037	1.684ProPro: 1.684 ± 0.05	1.937ProGln: 1.937 ± 0.042	1.817ProArg: 1.817 ± 0.045	2.301ProSer: 2.301 ± 0.06	1.857ProThr: 1.857 ± 0.059	3.715ProVal: 3.715 ± 0.066	0.343ProTrp: 0.343 ± 0.021	1.503ProTyr: 1.503 ± 0.046	0.0ProXaa: 0.0 ± 0.0
Gln	3.105GlnAla: 3.105 ± 0.065	0.391GlnCys: 0.391 ± 0.02	1.543GlnAsp: 1.543 ± 0.037	2.634GlnGlu: 2.634 ± 0.063	1.184GlnPhe: 1.184 ± 0.036	2.405GlnGly: 2.405 ± 0.056	0.531GlnHis: 0.531 ± 0.025	2.096GlnIle: 2.096 ± 0.051	2.448GlnLys: 2.448 ± 0.066	3.203GlnLeu: 3.203 ± 0.061	1.119GlnMet: 1.119 ± 0.038	1.76GlnAsn: 1.76 ± 0.045	1.24GlnPro: 1.24 ± 0.038	1.425GlnGln: 1.425 ± 0.044	2.08GlnArg: 2.08 ± 0.055	2.167GlnSer: 2.167 ± 0.053	1.63GlnThr: 1.63 ± 0.045	2.307GlnVal: 2.307 ± 0.053	0.289GlnTrp: 0.289 ± 0.018	1.25GlnTyr: 1.25 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	5.049ArgAla: 5.049 ± 0.082	0.956ArgCys: 0.956 ± 0.04	2.984ArgAsp: 2.984 ± 0.064	5.269ArgGlu: 5.269 ± 0.12	2.53ArgPhe: 2.53 ± 0.057	3.953ArgGly: 3.953 ± 0.083	1.112ArgHis: 1.112 ± 0.036	3.18ArgIle: 3.18 ± 0.067	2.577ArgLys: 2.577 ± 0.065	6.287ArgLeu: 6.287 ± 0.103	1.7ArgMet: 1.7 ± 0.05	1.447ArgAsn: 1.447 ± 0.041	2.157ArgPro: 2.157 ± 0.05	2.676ArgGln: 2.676 ± 0.061	4.225ArgArg: 4.225 ± 0.104	3.035ArgSer: 3.035 ± 0.063	2.659ArgThr: 2.659 ± 0.058	3.716ArgVal: 3.716 ± 0.065	0.586ArgTrp: 0.586 ± 0.024	2.426ArgTyr: 2.426 ± 0.061	0.0ArgXaa: 0.0 ± 0.0
Ser	5.489SerAla: 5.489 ± 0.1	0.972SerCys: 0.972 ± 0.041	3.002SerAsp: 3.002 ± 0.09	3.572SerGlu: 3.572 ± 0.065	2.797SerPhe: 2.797 ± 0.06	6.02SerGly: 6.02 ± 0.123	1.016SerHis: 1.016 ± 0.031	3.161SerIle: 3.161 ± 0.063	2.351SerLys: 2.351 ± 0.056	6.32SerLeu: 6.32 ± 0.103	1.537SerMet: 1.537 ± 0.044	1.61SerAsn: 1.61 ± 0.05	2.578SerPro: 2.578 ± 0.053	2.039SerGln: 2.039 ± 0.051	3.288SerArg: 3.288 ± 0.059	4.06SerSer: 4.06 ± 0.159	2.8SerThr: 2.8 ± 0.072	4.511SerVal: 4.511 ± 0.077	0.562SerTrp: 0.562 ± 0.028	2.288SerTyr: 2.288 ± 0.067	0.0SerXaa: 0.0 ± 0.0
Thr	5.074ThrAla: 5.074 ± 0.107	0.605ThrCys: 0.605 ± 0.027	2.576ThrAsp: 2.576 ± 0.073	2.643ThrGlu: 2.643 ± 0.06	2.015ThrPhe: 2.015 ± 0.049	4.802ThrGly: 4.802 ± 0.09	0.792ThrHis: 0.792 ± 0.033	3.17ThrIle: 3.17 ± 0.075	1.903ThrLys: 1.903 ± 0.055	5.603ThrLeu: 5.603 ± 0.081	1.304ThrMet: 1.304 ± 0.039	1.388ThrAsn: 1.388 ± 0.052	2.7ThrPro: 2.7 ± 0.066	1.356ThrGln: 1.356 ± 0.042	2.372ThrArg: 2.372 ± 0.05	2.635ThrSer: 2.635 ± 0.074	2.578ThrThr: 2.578 ± 0.062	5.007ThrVal: 5.007 ± 0.102	0.429ThrTrp: 0.429 ± 0.025	1.596ThrTyr: 1.596 ± 0.058	0.0ThrXaa: 0.0 ± 0.0
Val	5.87ValAla: 5.87 ± 0.092	1.479ValCys: 1.479 ± 0.044	3.702ValAsp: 3.702 ± 0.071	4.248ValGlu: 4.248 ± 0.071	2.882ValPhe: 2.882 ± 0.056	5.122ValGly: 5.122 ± 0.079	1.164ValHis: 1.164 ± 0.042	4.337ValIle: 4.337 ± 0.081	3.216ValLys: 3.216 ± 0.081	7.557ValLeu: 7.557 ± 0.107	1.906ValMet: 1.906 ± 0.056	2.205ValAsn: 2.205 ± 0.06	3.007ValPro: 3.007 ± 0.057	2.299ValGln: 2.299 ± 0.059	4.2ValArg: 4.2 ± 0.076	4.882ValSer: 4.882 ± 0.078	4.038ValThr: 4.038 ± 0.112	5.253ValVal: 5.253 ± 0.086	0.644ValTrp: 0.644 ± 0.026	2.505ValTyr: 2.505 ± 0.059	0.0ValXaa: 0.0 ± 0.0
Trp	0.681TrpAla: 0.681 ± 0.029	0.178TrpCys: 0.178 ± 0.014	0.583TrpAsp: 0.583 ± 0.029	0.671TrpGlu: 0.671 ± 0.029	0.375TrpPhe: 0.375 ± 0.019	0.758TrpGly: 0.758 ± 0.032	0.185TrpHis: 0.185 ± 0.014	0.461TrpIle: 0.461 ± 0.026	0.434TrpLys: 0.434 ± 0.023	0.952TrpLeu: 0.952 ± 0.036	0.295TrpMet: 0.295 ± 0.017	0.361TrpAsn: 0.361 ± 0.019	0.286TrpPro: 0.286 ± 0.018	0.442TrpGln: 0.442 ± 0.026	0.57TrpArg: 0.57 ± 0.025	0.525TrpSer: 0.525 ± 0.025	0.459TrpThr: 0.459 ± 0.036	0.53TrpVal: 0.53 ± 0.026	0.118TrpTrp: 0.118 ± 0.011	0.345TrpTyr: 0.345 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.905TyrAla: 2.905 ± 0.055	0.614TyrCys: 0.614 ± 0.026	2.217TyrAsp: 2.217 ± 0.049	2.451TyrGlu: 2.451 ± 0.057	1.57TyrPhe: 1.57 ± 0.044	2.919TyrGly: 2.919 ± 0.055	0.675TyrHis: 0.675 ± 0.031	2.031TyrIle: 2.031 ± 0.048	1.482TyrLys: 1.482 ± 0.06	3.632TyrLeu: 3.632 ± 0.067	0.72TyrMet: 0.72 ± 0.029	1.392TyrAsn: 1.392 ± 0.04	1.61TyrPro: 1.61 ± 0.049	1.398TyrGln: 1.398 ± 0.044	2.362TyrArg: 2.362 ± 0.056	2.16TyrSer: 2.16 ± 0.06	2.092TyrThr: 2.092 ± 0.074	2.091TyrVal: 2.091 ± 0.053	0.358TyrTrp: 0.358 ± 0.02	1.409TyrTyr: 1.409 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.002

Statistics based on 2808 proteins (875103 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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