Amino acid dipepetide frequency for endosymbiont GvMRE of Glomus versiforme

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.892AlaAla: 1.892 ± 0.078
0.523AlaCys: 0.523 ± 0.031
1.966AlaAsp: 1.966 ± 0.056
3.874AlaGlu: 3.874 ± 0.107
1.862AlaPhe: 1.862 ± 0.056
2.284AlaGly: 2.284 ± 0.073
0.701AlaHis: 0.701 ± 0.039
3.222AlaIle: 3.222 ± 0.083
5.011AlaLys: 5.011 ± 0.104
3.918AlaLeu: 3.918 ± 0.081
0.679AlaMet: 0.679 ± 0.04
2.945AlaAsn: 2.945 ± 0.076
1.12AlaPro: 1.12 ± 0.052
2.355AlaGln: 2.355 ± 0.105
2.17AlaArg: 2.17 ± 0.065
2.38AlaSer: 2.38 ± 0.061
2.291AlaThr: 2.291 ± 0.065
1.919AlaVal: 1.919 ± 0.065
0.805AlaTrp: 0.805 ± 0.047
1.6AlaTyr: 1.6 ± 0.054
0.0AlaXaa: 0.0 ± 0.0
Cys
0.49CysAla: 0.49 ± 0.032
0.226CysCys: 0.226 ± 0.019
0.577CysAsp: 0.577 ± 0.031
0.849CysGlu: 0.849 ± 0.036
0.815CysPhe: 0.815 ± 0.037
0.753CysGly: 0.753 ± 0.038
0.359CysHis: 0.359 ± 0.028
0.476CysIle: 0.476 ± 0.03
0.916CysLys: 0.916 ± 0.042
1.561CysLeu: 1.561 ± 0.064
0.138CysMet: 0.138 ± 0.016
0.557CysAsn: 0.557 ± 0.033
0.674CysPro: 0.674 ± 0.035
1.249CysGln: 1.249 ± 0.054
0.604CysArg: 0.604 ± 0.029
1.139CysSer: 1.139 ± 0.052
0.257CysThr: 0.257 ± 0.02
0.501CysVal: 0.501 ± 0.032
0.345CysTrp: 0.345 ± 0.025
0.56CysTyr: 0.56 ± 0.032
0.0CysXaa: 0.0 ± 0.0
Asp
1.432AspAla: 1.432 ± 0.051
0.823AspCys: 0.823 ± 0.04
2.132AspAsp: 2.132 ± 0.078
3.442AspGlu: 3.442 ± 0.089
2.88AspPhe: 2.88 ± 0.08
1.847AspGly: 1.847 ± 0.064
0.577AspHis: 0.577 ± 0.035
3.638AspIle: 3.638 ± 0.094
5.627AspLys: 5.627 ± 0.127
5.179AspLeu: 5.179 ± 0.095
0.582AspMet: 0.582 ± 0.03
3.333AspAsn: 3.333 ± 0.089
1.548AspPro: 1.548 ± 0.073
1.674AspGln: 1.674 ± 0.052
1.483AspArg: 1.483 ± 0.052
2.306AspSer: 2.306 ± 0.062
1.858AspThr: 1.858 ± 0.059
1.313AspVal: 1.313 ± 0.048
1.115AspTrp: 1.115 ± 0.046
2.606AspTyr: 2.606 ± 0.073
0.0AspXaa: 0.0 ± 0.0
Glu
3.812GluAla: 3.812 ± 0.104
0.837GluCys: 0.837 ± 0.037
3.168GluAsp: 3.168 ± 0.073
9.146GluGlu: 9.146 ± 0.216
3.247GluPhe: 3.247 ± 0.081
2.997GluGly: 2.997 ± 0.079
1.13GluHis: 1.13 ± 0.046
8.624GluIle: 8.624 ± 0.151
13.61GluLys: 13.61 ± 0.184
9.241GluLeu: 9.241 ± 0.202
1.405GluMet: 1.405 ± 0.061
5.974GluAsn: 5.974 ± 0.129
1.952GluPro: 1.952 ± 0.071
4.3GluGln: 4.3 ± 0.162
4.191GluArg: 4.191 ± 0.109
3.247GluSer: 3.247 ± 0.081
4.369GluThr: 4.369 ± 0.104
4.312GluVal: 4.312 ± 0.076
1.531GluTrp: 1.531 ± 0.064
2.727GluTyr: 2.727 ± 0.069
0.0GluXaa: 0.0 ± 0.0
Phe
2.333PheAla: 2.333 ± 0.064
0.914PheCys: 0.914 ± 0.041
2.221PheAsp: 2.221 ± 0.067
2.417PheGlu: 2.417 ± 0.056
3.14PhePhe: 3.14 ± 0.119
1.877PheGly: 1.877 ± 0.064
0.805PheHis: 0.805 ± 0.038
3.166PheIle: 3.166 ± 0.086
3.093PheLys: 3.093 ± 0.084
5.313PheLeu: 5.313 ± 0.118
0.572PheMet: 0.572 ± 0.034
2.477PheAsn: 2.477 ± 0.061
1.796PhePro: 1.796 ± 0.051
2.105PheGln: 2.105 ± 0.07
1.828PheArg: 1.828 ± 0.052
3.658PheSer: 3.658 ± 0.097
2.657PheThr: 2.657 ± 0.074
1.998PheVal: 1.998 ± 0.063
1.02PheTrp: 1.02 ± 0.049
2.182PheTyr: 2.182 ± 0.068
0.0PheXaa: 0.0 ± 0.0
Gly
1.701GlyAla: 1.701 ± 0.063
0.49GlyCys: 0.49 ± 0.027
2.06GlyAsp: 2.06 ± 0.072
3.795GlyGlu: 3.795 ± 0.076
2.117GlyPhe: 2.117 ± 0.066
2.99GlyGly: 2.99 ± 0.103
0.782GlyHis: 0.782 ± 0.038
3.722GlyIle: 3.722 ± 0.089
5.54GlyLys: 5.54 ± 0.101
3.972GlyLeu: 3.972 ± 0.098
0.657GlyMet: 0.657 ± 0.035
2.699GlyAsn: 2.699 ± 0.08
0.647GlyPro: 0.647 ± 0.034
1.553GlyGln: 1.553 ± 0.062
1.924GlyArg: 1.924 ± 0.074
2.838GlySer: 2.838 ± 0.08
2.229GlyThr: 2.229 ± 0.066
2.112GlyVal: 2.112 ± 0.051
0.83GlyTrp: 0.83 ± 0.04
1.741GlyTyr: 1.741 ± 0.05
0.0GlyXaa: 0.0 ± 0.0
His
0.657HisAla: 0.657 ± 0.038
0.299HisCys: 0.299 ± 0.021
0.607HisAsp: 0.607 ± 0.034
1.09HisGlu: 1.09 ± 0.05
0.901HisPhe: 0.901 ± 0.037
0.761HisGly: 0.761 ± 0.039
0.387HisHis: 0.387 ± 0.029
0.931HisIle: 0.931 ± 0.036
1.187HisLys: 1.187 ± 0.05
1.914HisLeu: 1.914 ± 0.057
0.208HisMet: 0.208 ± 0.018
0.921HisAsn: 0.921 ± 0.039
0.725HisPro: 0.725 ± 0.041
1.159HisGln: 1.159 ± 0.049
0.654HisArg: 0.654 ± 0.038
1.092HisSer: 1.092 ± 0.042
0.701HisThr: 0.701 ± 0.03
0.507HisVal: 0.507 ± 0.03
0.414HisTrp: 0.414 ± 0.026
0.933HisTyr: 0.933 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
3.898IleAla: 3.898 ± 0.082
1.102IleCys: 1.102 ± 0.049
4.054IleAsp: 4.054 ± 0.093
6.102IleGlu: 6.102 ± 0.102
3.671IlePhe: 3.671 ± 0.093
3.321IleGly: 3.321 ± 0.079
1.263IleHis: 1.263 ± 0.053
7.24IleIle: 7.24 ± 0.136
8.579IleLys: 8.579 ± 0.126
6.736IleLeu: 6.736 ± 0.133
1.001IleMet: 1.001 ± 0.047
5.825IleAsn: 5.825 ± 0.099
2.486IlePro: 2.486 ± 0.07
3.344IleGln: 3.344 ± 0.083
3.071IleArg: 3.071 ± 0.069
5.402IleSer: 5.402 ± 0.099
4.53IleThr: 4.53 ± 0.098
3.48IleVal: 3.48 ± 0.074
0.996IleTrp: 0.996 ± 0.044
2.757IleTyr: 2.757 ± 0.073
0.0IleXaa: 0.0 ± 0.0
Lys
4.292LysAla: 4.292 ± 0.093
1.11LysCys: 1.11 ± 0.048
5.66LysAsp: 5.66 ± 0.137
13.171LysGlu: 13.171 ± 0.197
3.532LysPhe: 3.532 ± 0.083
4.617LysGly: 4.617 ± 0.106
1.597LysHis: 1.597 ± 0.052
10.248LysIle: 10.248 ± 0.152
15.299LysLys: 15.299 ± 0.242
10.492LysLeu: 10.492 ± 0.145
2.048LysMet: 2.048 ± 0.057
8.082LysAsn: 8.082 ± 0.134
3.037LysPro: 3.037 ± 0.079
5.478LysGln: 5.478 ± 0.128
4.262LysArg: 4.262 ± 0.1
5.585LysSer: 5.585 ± 0.099
5.624LysThr: 5.624 ± 0.104
5.077LysVal: 5.077 ± 0.098
1.717LysTrp: 1.717 ± 0.064
3.49LysTyr: 3.49 ± 0.087
0.0LysXaa: 0.0 ± 0.0
Leu
5.746LeuAla: 5.746 ± 0.097
0.99LeuCys: 0.99 ± 0.043
4.646LeuAsp: 4.646 ± 0.096
9.469LeuGlu: 9.469 ± 0.181
4.295LeuPhe: 4.295 ± 0.112
4.634LeuGly: 4.634 ± 0.106
1.384LeuHis: 1.384 ± 0.043
7.985LeuIle: 7.985 ± 0.141
10.316LeuLys: 10.316 ± 0.146
9.506LeuLeu: 9.506 ± 0.157
1.102LeuMet: 1.102 ± 0.04
6.412LeuAsn: 6.412 ± 0.119
3.559LeuPro: 3.559 ± 0.078
4.282LeuGln: 4.282 ± 0.111
4.022LeuArg: 4.022 ± 0.082
6.09LeuSer: 6.09 ± 0.12
6.377LeuThr: 6.377 ± 0.12
5.245LeuVal: 5.245 ± 0.111
1.342LeuTrp: 1.342 ± 0.045
2.343LeuTyr: 2.343 ± 0.062
0.0LeuXaa: 0.0 ± 0.0
Met
0.771MetAla: 0.771 ± 0.036
0.101MetCys: 0.101 ± 0.014
0.507MetAsp: 0.507 ± 0.033
1.023MetGlu: 1.023 ± 0.041
0.553MetPhe: 0.553 ± 0.03
0.683MetGly: 0.683 ± 0.052
0.102MetHis: 0.102 ± 0.012
1.001MetIle: 1.001 ± 0.042
1.494MetLys: 1.494 ± 0.049
1.166MetLeu: 1.166 ± 0.043
0.226MetMet: 0.226 ± 0.02
1.323MetAsn: 1.323 ± 0.048
0.639MetPro: 0.639 ± 0.032
0.362MetGln: 0.362 ± 0.026
0.538MetArg: 0.538 ± 0.03
0.943MetSer: 0.943 ± 0.039
1.036MetThr: 1.036 ± 0.039
0.706MetVal: 0.706 ± 0.033
0.106MetTrp: 0.106 ± 0.011
0.223MetTyr: 0.223 ± 0.018
0.0MetXaa: 0.0 ± 0.0
Asn
2.323AsnAla: 2.323 ± 0.065
1.35AsnCys: 1.35 ± 0.052
2.782AsnAsp: 2.782 ± 0.08
4.961AsnGlu: 4.961 ± 0.117
3.5AsnPhe: 3.5 ± 0.079
2.268AsnGly: 2.268 ± 0.072
1.255AsnHis: 1.255 ± 0.044
4.604AsnIle: 4.604 ± 0.091
7.245AsnLys: 7.245 ± 0.127
7.775AsnLeu: 7.775 ± 0.151
0.896AsnMet: 0.896 ± 0.037
5.461AsnAsn: 5.461 ± 0.132
2.507AsnPro: 2.507 ± 0.06
4.441AsnGln: 4.441 ± 0.139
2.256AsnArg: 2.256 ± 0.063
4.443AsnSer: 4.443 ± 0.104
2.544AsnThr: 2.544 ± 0.077
2.029AsnVal: 2.029 ± 0.061
1.414AsnTrp: 1.414 ± 0.051
3.534AsnTyr: 3.534 ± 0.082
0.0AsnXaa: 0.0 ± 0.0
Pro
1.4ProAla: 1.4 ± 0.055
0.367ProCys: 0.367 ± 0.024
1.55ProAsp: 1.55 ± 0.074
2.898ProGlu: 2.898 ± 0.079
1.476ProPhe: 1.476 ± 0.059
1.33ProGly: 1.33 ± 0.063
0.671ProHis: 0.671 ± 0.031
2.034ProIle: 2.034 ± 0.071
2.777ProLys: 2.777 ± 0.071
3.084ProLeu: 3.084 ± 0.08
0.283ProMet: 0.283 ± 0.024
2.338ProAsn: 2.338 ± 0.071
1.196ProPro: 1.196 ± 0.05
1.738ProGln: 1.738 ± 0.058
1.142ProArg: 1.142 ± 0.047
2.164ProSer: 2.164 ± 0.055
1.689ProThr: 1.689 ± 0.062
1.4ProVal: 1.4 ± 0.05
0.527ProTrp: 0.527 ± 0.028
1.273ProTyr: 1.273 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
2.88GlnAla: 2.88 ± 0.109
0.396GlnCys: 0.396 ± 0.026
1.917GlnAsp: 1.917 ± 0.066
6.341GlnGlu: 6.341 ± 0.185
1.449GlnPhe: 1.449 ± 0.053
2.122GlnGly: 2.122 ± 0.062
0.631GlnHis: 0.631 ± 0.033
4.277GlnIle: 4.277 ± 0.1
6.959GlnLys: 6.959 ± 0.151
4.787GlnLeu: 4.787 ± 0.139
0.604GlnMet: 0.604 ± 0.035
3.212GlnAsn: 3.212 ± 0.083
1.338GlnPro: 1.338 ± 0.058
3.807GlnGln: 3.807 ± 0.15
2.028GlnArg: 2.028 ± 0.064
2.278GlnSer: 2.278 ± 0.065
2.732GlnThr: 2.732 ± 0.111
2.197GlnVal: 2.197 ± 0.069
0.661GlnTrp: 0.661 ± 0.032
0.995GlnTyr: 0.995 ± 0.043
0.0GlnXaa: 0.0 ± 0.0
Arg
1.52ArgAla: 1.52 ± 0.052
0.438ArgCys: 0.438 ± 0.028
1.977ArgAsp: 1.977 ± 0.068
4.508ArgGlu: 4.508 ± 0.12
1.603ArgPhe: 1.603 ± 0.051
2.018ArgGly: 2.018 ± 0.065
0.621ArgHis: 0.621 ± 0.039
3.076ArgIle: 3.076 ± 0.076
5.122ArgLys: 5.122 ± 0.103
3.576ArgLeu: 3.576 ± 0.08
0.626ArgMet: 0.626 ± 0.033
2.588ArgAsn: 2.588 ± 0.079
1.062ArgPro: 1.062 ± 0.044
2.286ArgGln: 2.286 ± 0.068
1.833ArgArg: 1.833 ± 0.056
1.842ArgSer: 1.842 ± 0.061
1.84ArgThr: 1.84 ± 0.058
1.816ArgVal: 1.816 ± 0.058
0.599ArgTrp: 0.599 ± 0.031
1.348ArgTyr: 1.348 ± 0.046
0.0ArgXaa: 0.0 ± 0.0
Ser
2.241SerAla: 2.241 ± 0.064
0.817SerCys: 0.817 ± 0.044
2.672SerAsp: 2.672 ± 0.076
4.782SerGlu: 4.782 ± 0.089
3.101SerPhe: 3.101 ± 0.086
2.913SerGly: 2.913 ± 0.072
1.1SerHis: 1.1 ± 0.04
3.587SerIle: 3.587 ± 0.085
5.867SerLys: 5.867 ± 0.106
6.821SerLeu: 6.821 ± 0.127
0.748SerMet: 0.748 ± 0.037
3.359SerAsn: 3.359 ± 0.083
2.273SerPro: 2.273 ± 0.07
3.836SerGln: 3.836 ± 0.102
2.348SerArg: 2.348 ± 0.058
4.359SerSer: 4.359 ± 0.128
2.487SerThr: 2.487 ± 0.079
2.306SerVal: 2.306 ± 0.071
1.06SerTrp: 1.06 ± 0.046
2.09SerTyr: 2.09 ± 0.062
0.0SerXaa: 0.0 ± 0.0
Thr
2.209ThrAla: 2.209 ± 0.068
0.599ThrCys: 0.599 ± 0.034
2.328ThrAsp: 2.328 ± 0.062
4.124ThrGlu: 4.124 ± 0.103
2.246ThrPhe: 2.246 ± 0.065
2.524ThrGly: 2.524 ± 0.075
0.874ThrHis: 0.874 ± 0.039
3.891ThrIle: 3.891 ± 0.082
5.788ThrLys: 5.788 ± 0.118
4.141ThrLeu: 4.141 ± 0.094
0.478ThrMet: 0.478 ± 0.029
3.863ThrAsn: 3.863 ± 0.098
1.821ThrPro: 1.821 ± 0.062
2.222ThrGln: 2.222 ± 0.078
1.845ThrArg: 1.845 ± 0.058
3.172ThrSer: 3.172 ± 0.081
2.569ThrThr: 2.569 ± 0.075
1.974ThrVal: 1.974 ± 0.055
0.745ThrTrp: 0.745 ± 0.037
1.82ThrTyr: 1.82 ± 0.053
0.0ThrXaa: 0.0 ± 0.0
Val
1.996ValAla: 1.996 ± 0.058
0.652ValCys: 0.652 ± 0.036
2.212ValAsp: 2.212 ± 0.064
3.616ValGlu: 3.616 ± 0.08
2.185ValPhe: 2.185 ± 0.069
2.133ValGly: 2.133 ± 0.066
0.612ValHis: 0.612 ± 0.03
3.774ValIle: 3.774 ± 0.083
4.904ValLys: 4.904 ± 0.1
4.057ValLeu: 4.057 ± 0.087
0.604ValMet: 0.604 ± 0.038
3.19ValAsn: 3.19 ± 0.078
1.298ValPro: 1.298 ± 0.048
1.352ValGln: 1.352 ± 0.051
1.714ValArg: 1.714 ± 0.056
3.054ValSer: 3.054 ± 0.08
1.263ValThr: 1.263 ± 0.047
2.296ValVal: 2.296 ± 0.07
0.656ValTrp: 0.656 ± 0.037
1.768ValTyr: 1.768 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.636TrpAla: 0.636 ± 0.034
0.215TrpCys: 0.215 ± 0.021
0.775TrpAsp: 0.775 ± 0.03
1.741TrpGlu: 1.741 ± 0.053
0.75TrpPhe: 0.75 ± 0.046
0.854TrpGly: 0.854 ± 0.039
0.257TrpHis: 0.257 ± 0.021
1.421TrpIle: 1.421 ± 0.055
2.279TrpLys: 2.279 ± 0.069
1.785TrpLeu: 1.785 ± 0.057
0.275TrpMet: 0.275 ± 0.021
1.04TrpAsn: 1.04 ± 0.044
0.369TrpPro: 0.369 ± 0.024
0.949TrpGln: 0.949 ± 0.037
0.686TrpArg: 0.686 ± 0.035
0.574TrpSer: 0.574 ± 0.028
0.909TrpThr: 0.909 ± 0.047
0.8TrpVal: 0.8 ± 0.037
0.428TrpTrp: 0.428 ± 0.03
0.434TrpTyr: 0.434 ± 0.027
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.29TyrAla: 1.29 ± 0.045
0.798TyrCys: 0.798 ± 0.041
1.585TyrAsp: 1.585 ± 0.053
2.474TyrGlu: 2.474 ± 0.062
2.247TyrPhe: 2.247 ± 0.071
1.471TyrGly: 1.471 ± 0.051
0.941TyrHis: 0.941 ± 0.039
1.942TyrIle: 1.942 ± 0.062
2.804TyrLys: 2.804 ± 0.063
4.72TyrLeu: 4.72 ± 0.102
0.371TyrMet: 0.371 ± 0.026
1.991TyrAsn: 1.991 ± 0.063
1.29TyrPro: 1.29 ± 0.049
3.116TyrGln: 3.116 ± 0.092
1.699TyrArg: 1.699 ± 0.05
2.204TyrSer: 2.204 ± 0.058
1.27TyrThr: 1.27 ± 0.049
1.348TyrVal: 1.348 ± 0.048
0.864TyrTrp: 0.864 ± 0.044
1.917TyrTyr: 1.917 ± 0.065
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2357 proteins (596243 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski