Amino acid dipepetide frequency for Capybara microvirus Cap3_SP_588

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.462AlaAla: 1.462 ± 1.425
1.462AlaCys: 1.462 ± 0.956
7.31AlaAsp: 7.31 ± 2.27
3.655AlaGlu: 3.655 ± 2.658
4.386AlaPhe: 4.386 ± 0.766
2.924AlaGly: 2.924 ± 1.426
0.0AlaHis: 0.0 ± 0.0
4.386AlaIle: 4.386 ± 2.414
2.193AlaLys: 2.193 ± 1.235
2.924AlaLeu: 2.924 ± 1.913
1.462AlaMet: 1.462 ± 0.713
4.386AlaAsn: 4.386 ± 1.918
1.462AlaPro: 1.462 ± 0.562
4.386AlaGln: 4.386 ± 3.432
3.655AlaArg: 3.655 ± 1.123
5.117AlaSer: 5.117 ± 3.65
4.386AlaThr: 4.386 ± 2.139
2.193AlaVal: 2.193 ± 0.983
0.731AlaTrp: 0.731 ± 0.478
6.579AlaTyr: 6.579 ± 2.383
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.731CysAsp: 0.731 ± 0.998
0.0CysGlu: 0.0 ± 0.0
1.462CysPhe: 1.462 ± 0.562
0.731CysGly: 0.731 ± 0.638
0.0CysHis: 0.0 ± 0.0
0.731CysIle: 0.731 ± 1.288
1.462CysLys: 1.462 ± 1.277
0.731CysLeu: 0.731 ± 0.638
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.731CysSer: 0.731 ± 0.638
1.462CysThr: 1.462 ± 0.562
0.0CysVal: 0.0 ± 0.0
0.731CysTrp: 0.731 ± 0.638
0.731CysTyr: 0.731 ± 0.638
0.0CysXaa: 0.0 ± 0.0
Asp
5.117AspAla: 5.117 ± 1.896
0.731AspCys: 0.731 ± 0.638
2.193AspAsp: 2.193 ± 1.104
5.848AspGlu: 5.848 ± 1.687
5.848AspPhe: 5.848 ± 1.479
3.655AspGly: 3.655 ± 2.355
0.0AspHis: 0.0 ± 0.0
6.579AspIle: 6.579 ± 0.845
1.462AspLys: 1.462 ± 1.277
3.655AspLeu: 3.655 ± 2.075
0.731AspMet: 0.731 ± 0.478
5.848AspAsn: 5.848 ± 2.367
2.193AspPro: 2.193 ± 1.235
0.731AspGln: 0.731 ± 0.998
2.193AspArg: 2.193 ± 1.061
6.579AspSer: 6.579 ± 2.563
2.193AspThr: 2.193 ± 1.135
2.924AspVal: 2.924 ± 1.113
4.386AspTrp: 4.386 ± 1.207
5.117AspTyr: 5.117 ± 1.57
0.0AspXaa: 0.0 ± 0.0
Glu
2.193GluAla: 2.193 ± 0.983
0.731GluCys: 0.731 ± 0.638
1.462GluAsp: 1.462 ± 0.713
1.462GluGlu: 1.462 ± 0.562
2.924GluPhe: 2.924 ± 1.455
0.0GluGly: 0.0 ± 0.0
2.193GluHis: 2.193 ± 1.435
2.924GluIle: 2.924 ± 1.714
3.655GluLys: 3.655 ± 2.075
3.655GluLeu: 3.655 ± 2.255
1.462GluMet: 1.462 ± 1.652
4.386GluAsn: 4.386 ± 1.311
1.462GluPro: 1.462 ± 0.956
2.924GluGln: 2.924 ± 1.913
1.462GluArg: 1.462 ± 1.167
7.31GluSer: 7.31 ± 3.759
2.193GluThr: 2.193 ± 0.826
6.579GluVal: 6.579 ± 2.271
0.0GluTrp: 0.0 ± 0.0
2.924GluTyr: 2.924 ± 1.227
0.0GluXaa: 0.0 ± 0.0
Phe
4.386PheAla: 4.386 ± 1.448
0.0PheCys: 0.0 ± 0.0
3.655PheAsp: 3.655 ± 1.33
2.193PheGlu: 2.193 ± 1.235
4.386PhePhe: 4.386 ± 1.217
7.31PheGly: 7.31 ± 1.181
0.731PheHis: 0.731 ± 0.478
0.731PheIle: 0.731 ± 1.288
3.655PheLys: 3.655 ± 0.62
1.462PheLeu: 1.462 ± 0.562
2.193PheMet: 2.193 ± 0.786
5.848PheAsn: 5.848 ± 3.071
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
2.193PheArg: 2.193 ± 0.826
2.924PheSer: 2.924 ± 1.37
2.924PheThr: 2.924 ± 0.816
4.386PheVal: 4.386 ± 1.652
0.0PheTrp: 0.0 ± 0.0
2.924PheTyr: 2.924 ± 1.491
0.0PheXaa: 0.0 ± 0.0
Gly
5.117GlyAla: 5.117 ± 1.157
0.0GlyCys: 0.0 ± 0.0
4.386GlyAsp: 4.386 ± 0.945
2.924GlyGlu: 2.924 ± 0.74
2.924GlyPhe: 2.924 ± 1.227
5.848GlyGly: 5.848 ± 3.062
0.731GlyHis: 0.731 ± 0.713
5.117GlyIle: 5.117 ± 2.157
2.924GlyLys: 2.924 ± 1.493
3.655GlyLeu: 3.655 ± 2.045
0.0GlyMet: 0.0 ± 1.076
7.31GlyAsn: 7.31 ± 2.978
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
0.731GlyArg: 0.731 ± 0.478
5.848GlySer: 5.848 ± 2.032
5.117GlyThr: 5.117 ± 1.993
5.117GlyVal: 5.117 ± 2.068
0.0GlyTrp: 0.0 ± 0.0
5.117GlyTyr: 5.117 ± 1.101
0.0GlyXaa: 0.0 ± 0.0
His
1.462HisAla: 1.462 ± 1.028
0.0HisCys: 0.0 ± 0.0
0.731HisAsp: 0.731 ± 0.478
0.731HisGlu: 0.731 ± 0.478
2.193HisPhe: 2.193 ± 0.826
0.731HisGly: 0.731 ± 0.478
0.0HisHis: 0.0 ± 0.0
0.731HisIle: 0.731 ± 0.478
1.462HisLys: 1.462 ± 0.92
1.462HisLeu: 1.462 ± 0.92
0.731HisMet: 0.731 ± 0.672
1.462HisAsn: 1.462 ± 1.413
0.731HisPro: 0.731 ± 0.478
0.731HisGln: 0.731 ± 0.638
0.0HisArg: 0.0 ± 0.0
1.462HisSer: 1.462 ± 0.562
1.462HisThr: 1.462 ± 0.956
0.731HisVal: 0.731 ± 0.478
0.731HisTrp: 0.731 ± 0.478
1.462HisTyr: 1.462 ± 0.562
0.0HisXaa: 0.0 ± 0.0
Ile
5.117IleAla: 5.117 ± 1.776
0.731IleCys: 0.731 ± 0.638
4.386IleAsp: 4.386 ± 1.652
1.462IleGlu: 1.462 ± 1.167
2.193IlePhe: 2.193 ± 1.343
5.848IleGly: 5.848 ± 2.451
0.731IleHis: 0.731 ± 0.638
0.731IleIle: 0.731 ± 0.478
3.655IleLys: 3.655 ± 1.416
2.924IleLeu: 2.924 ± 1.992
0.0IleMet: 0.0 ± 0.0
8.041IleAsn: 8.041 ± 1.209
5.848IlePro: 5.848 ± 1.369
2.193IleGln: 2.193 ± 1.235
2.193IleArg: 2.193 ± 1.769
3.655IleSer: 3.655 ± 1.758
1.462IleThr: 1.462 ± 1.028
3.655IleVal: 3.655 ± 1.123
0.0IleTrp: 0.0 ± 0.0
7.31IleTyr: 7.31 ± 2.14
0.0IleXaa: 0.0 ± 0.0
Lys
4.386LysAla: 4.386 ± 1.514
0.0LysCys: 0.0 ± 0.0
5.117LysAsp: 5.117 ± 3.483
2.193LysGlu: 2.193 ± 0.757
3.655LysPhe: 3.655 ± 0.62
1.462LysGly: 1.462 ± 0.956
1.462LysHis: 1.462 ± 0.92
4.386LysIle: 4.386 ± 2.013
4.386LysLys: 4.386 ± 2.34
3.655LysLeu: 3.655 ± 2.475
1.462LysMet: 1.462 ± 0.92
2.924LysAsn: 2.924 ± 2.401
2.193LysPro: 2.193 ± 0.757
2.924LysGln: 2.924 ± 2.184
2.193LysArg: 2.193 ± 1.104
2.193LysSer: 2.193 ± 0.983
5.848LysThr: 5.848 ± 3.414
2.924LysVal: 2.924 ± 1.491
0.731LysTrp: 0.731 ± 0.638
2.924LysTyr: 2.924 ± 1.714
0.0LysXaa: 0.0 ± 0.0
Leu
3.655LeuAla: 3.655 ± 1.247
0.731LeuCys: 0.731 ± 0.638
5.117LeuAsp: 5.117 ± 1.762
2.924LeuGlu: 2.924 ± 1.062
2.193LeuPhe: 2.193 ± 1.775
5.848LeuGly: 5.848 ± 2.62
1.462LeuHis: 1.462 ± 0.956
4.386LeuIle: 4.386 ± 3.199
4.386LeuLys: 4.386 ± 1.752
4.386LeuLeu: 4.386 ± 1.027
0.731LeuMet: 0.731 ± 0.638
5.848LeuAsn: 5.848 ± 2.373
5.848LeuPro: 5.848 ± 3.075
2.924LeuGln: 2.924 ± 1.372
3.655LeuArg: 3.655 ± 1.086
4.386LeuSer: 4.386 ± 2.516
1.462LeuThr: 1.462 ± 1.277
0.731LeuVal: 0.731 ± 1.288
0.0LeuTrp: 0.0 ± 0.0
4.386LeuTyr: 4.386 ± 2.208
0.0LeuXaa: 0.0 ± 0.0
Met
2.193MetAla: 2.193 ± 0.983
0.731MetCys: 0.731 ± 0.638
1.462MetAsp: 1.462 ± 0.956
0.731MetGlu: 0.731 ± 0.478
0.731MetPhe: 0.731 ± 0.713
2.193MetGly: 2.193 ± 0.983
0.0MetHis: 0.0 ± 0.0
0.731MetIle: 0.731 ± 0.638
0.0MetLys: 0.0 ± 0.0
1.462MetLeu: 1.462 ± 0.92
0.0MetMet: 0.0 ± 0.0
1.462MetAsn: 1.462 ± 1.277
0.731MetPro: 0.731 ± 0.478
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.193MetSer: 2.193 ± 1.414
1.462MetThr: 1.462 ± 0.562
1.462MetVal: 1.462 ± 1.772
0.0MetTrp: 0.0 ± 0.0
1.462MetTyr: 1.462 ± 1.167
0.0MetXaa: 0.0 ± 0.0
Asn
5.117AsnAla: 5.117 ± 1.762
0.0AsnCys: 0.0 ± 0.0
4.386AsnAsp: 4.386 ± 1.752
5.117AsnGlu: 5.117 ± 1.48
2.924AsnPhe: 2.924 ± 2.335
5.848AsnGly: 5.848 ± 3.544
2.193AsnHis: 2.193 ± 1.235
1.462AsnIle: 1.462 ± 0.713
9.503AsnLys: 9.503 ± 4.25
5.117AsnLeu: 5.117 ± 1.359
0.731AsnMet: 0.731 ± 0.998
8.772AsnAsn: 8.772 ± 1.149
5.117AsnPro: 5.117 ± 1.674
1.462AsnGln: 1.462 ± 0.713
2.924AsnArg: 2.924 ± 1.016
5.848AsnSer: 5.848 ± 1.544
2.193AsnThr: 2.193 ± 0.983
3.655AsnVal: 3.655 ± 1.33
0.731AsnTrp: 0.731 ± 0.713
5.848AsnTyr: 5.848 ± 1.258
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.731ProCys: 0.731 ± 0.638
2.924ProAsp: 2.924 ± 1.227
1.462ProGlu: 1.462 ± 0.562
2.924ProPhe: 2.924 ± 1.491
2.924ProGly: 2.924 ± 0.74
1.462ProHis: 1.462 ± 0.562
6.579ProIle: 6.579 ± 1.985
3.655ProLys: 3.655 ± 2.358
3.655ProLeu: 3.655 ± 1.757
1.462ProMet: 1.462 ± 0.562
1.462ProAsn: 1.462 ± 0.956
0.0ProPro: 0.0 ± 0.0
2.193ProGln: 2.193 ± 1.061
0.731ProArg: 0.731 ± 0.478
4.386ProSer: 4.386 ± 2.255
1.462ProThr: 1.462 ± 0.562
4.386ProVal: 4.386 ± 2.47
0.0ProTrp: 0.0 ± 0.0
3.655ProTyr: 3.655 ± 1.061
0.0ProXaa: 0.0 ± 0.0
Gln
3.655GlnAla: 3.655 ± 2.232
0.731GlnCys: 0.731 ± 0.998
1.462GlnAsp: 1.462 ± 1.277
2.924GlnGlu: 2.924 ± 2.028
0.0GlnPhe: 0.0 ± 0.0
2.193GlnGly: 2.193 ± 0.983
0.0GlnHis: 0.0 ± 0.0
2.193GlnIle: 2.193 ± 0.726
1.462GlnLys: 1.462 ± 0.562
1.462GlnLeu: 1.462 ± 0.956
1.462GlnMet: 1.462 ± 0.713
2.924GlnAsn: 2.924 ± 1.113
2.193GlnPro: 2.193 ± 1.435
2.193GlnGln: 2.193 ± 0.983
3.655GlnArg: 3.655 ± 1.123
3.655GlnSer: 3.655 ± 2.069
1.462GlnThr: 1.462 ± 0.956
2.193GlnVal: 2.193 ± 0.826
0.0GlnTrp: 0.0 ± 0.0
1.462GlnTyr: 1.462 ± 0.913
0.0GlnXaa: 0.0 ± 0.0
Arg
3.655ArgAla: 3.655 ± 1.39
0.731ArgCys: 0.731 ± 0.638
2.193ArgAsp: 2.193 ± 0.983
1.462ArgGlu: 1.462 ± 1.277
1.462ArgPhe: 1.462 ± 0.956
2.193ArgGly: 2.193 ± 1.852
0.731ArgHis: 0.731 ± 0.638
0.731ArgIle: 0.731 ± 0.478
2.193ArgLys: 2.193 ± 0.757
5.848ArgLeu: 5.848 ± 1.122
1.462ArgMet: 1.462 ± 0.956
2.924ArgAsn: 2.924 ± 1.227
2.193ArgPro: 2.193 ± 1.104
0.0ArgGln: 0.0 ± 0.0
1.462ArgArg: 1.462 ± 0.562
3.655ArgSer: 3.655 ± 1.669
2.193ArgThr: 2.193 ± 1.435
2.193ArgVal: 2.193 ± 1.061
0.0ArgTrp: 0.0 ± 0.0
2.924ArgTyr: 2.924 ± 1.125
0.0ArgXaa: 0.0 ± 0.0
Ser
6.579SerAla: 6.579 ± 3.046
1.462SerCys: 1.462 ± 1.413
6.579SerAsp: 6.579 ± 3.361
5.848SerGlu: 5.848 ± 2.267
2.924SerPhe: 2.924 ± 1.016
5.848SerGly: 5.848 ± 3.288
2.924SerHis: 2.924 ± 0.816
7.31SerIle: 7.31 ± 1.161
1.462SerLys: 1.462 ± 1.277
5.848SerLeu: 5.848 ± 1.598
0.731SerMet: 0.731 ± 0.638
3.655SerAsn: 3.655 ± 1.27
2.924SerPro: 2.924 ± 1.227
3.655SerGln: 3.655 ± 1.247
2.924SerArg: 2.924 ± 1.125
10.234SerSer: 10.234 ± 3.237
4.386SerThr: 4.386 ± 1.966
5.848SerVal: 5.848 ± 2.84
0.731SerTrp: 0.731 ± 0.478
2.193SerTyr: 2.193 ± 1.775
0.0SerXaa: 0.0 ± 0.0
Thr
2.193ThrAla: 2.193 ± 0.726
0.731ThrCys: 0.731 ± 0.638
3.655ThrAsp: 3.655 ± 1.235
2.924ThrGlu: 2.924 ± 1.062
0.731ThrPhe: 0.731 ± 0.478
2.193ThrGly: 2.193 ± 0.983
0.731ThrHis: 0.731 ± 0.478
4.386ThrIle: 4.386 ± 1.966
2.193ThrLys: 2.193 ± 0.983
3.655ThrLeu: 3.655 ± 1.086
0.731ThrMet: 0.731 ± 0.478
1.462ThrAsn: 1.462 ± 0.956
4.386ThrPro: 4.386 ± 1.501
2.193ThrGln: 2.193 ± 0.757
2.924ThrArg: 2.924 ± 1.37
4.386ThrSer: 4.386 ± 1.112
1.462ThrThr: 1.462 ± 0.713
3.655ThrVal: 3.655 ± 1.649
0.0ThrTrp: 0.0 ± 0.0
4.386ThrTyr: 4.386 ± 1.514
0.0ThrXaa: 0.0 ± 0.0
Val
4.386ValAla: 4.386 ± 2.869
0.0ValCys: 0.0 ± 0.0
4.386ValAsp: 4.386 ± 1.6
4.386ValGlu: 4.386 ± 2.159
2.924ValPhe: 2.924 ± 1.491
3.655ValGly: 3.655 ± 0.989
0.0ValHis: 0.0 ± 0.0
2.924ValIle: 2.924 ± 1.125
2.193ValLys: 2.193 ± 2.572
3.655ValLeu: 3.655 ± 1.27
0.731ValMet: 0.731 ± 0.63
4.386ValAsn: 4.386 ± 1.592
4.386ValPro: 4.386 ± 1.77
2.924ValGln: 2.924 ± 1.125
3.655ValArg: 3.655 ± 0.884
5.117ValSer: 5.117 ± 1.205
3.655ValThr: 3.655 ± 1.741
0.731ValVal: 0.731 ± 0.638
0.731ValTrp: 0.731 ± 0.478
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.731TrpAla: 0.731 ± 0.478
0.0TrpCys: 0.0 ± 0.0
0.731TrpAsp: 0.731 ± 0.478
0.731TrpGlu: 0.731 ± 0.478
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.462TrpHis: 1.462 ± 0.562
0.731TrpIle: 0.731 ± 0.478
0.0TrpLys: 0.0 ± 0.0
0.731TrpLeu: 0.731 ± 0.713
0.0TrpMet: 0.0 ± 0.0
1.462TrpAsn: 1.462 ± 0.713
0.731TrpPro: 0.731 ± 0.478
2.193TrpGln: 2.193 ± 1.414
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.462TrpThr: 1.462 ± 0.956
0.731TrpVal: 0.731 ± 0.638
0.0TrpTrp: 0.0 ± 0.0
0.731TrpTyr: 0.731 ± 0.478
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.655TyrAla: 3.655 ± 2.443
0.0TyrCys: 0.0 ± 0.0
5.117TyrAsp: 5.117 ± 1.803
2.924TyrGlu: 2.924 ± 1.489
5.117TyrPhe: 5.117 ± 1.868
2.193TyrGly: 2.193 ± 1.443
2.193TyrHis: 2.193 ± 1.39
4.386TyrIle: 4.386 ± 1.514
5.117TyrLys: 5.117 ± 1.923
5.117TyrLeu: 5.117 ± 1.274
2.193TyrMet: 2.193 ± 1.414
4.386TyrAsn: 4.386 ± 1.027
3.655TyrPro: 3.655 ± 1.319
3.655TyrGln: 3.655 ± 1.29
3.655TyrArg: 3.655 ± 1.669
4.386TyrSer: 4.386 ± 0.945
0.731TyrThr: 0.731 ± 0.638
0.731TyrVal: 0.731 ± 0.638
2.924TyrTrp: 2.924 ± 1.372
3.655TyrTyr: 3.655 ± 1.632
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1369 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski