Amino acid dipepetide frequency for Simian adenovirus 49

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.962AlaAla: 13.962 ± 1.945
1.334AlaCys: 1.334 ± 0.45
3.913AlaAsp: 3.913 ± 0.661
4.98AlaGlu: 4.98 ± 0.793
3.29AlaPhe: 3.29 ± 0.505
5.425AlaGly: 5.425 ± 0.868
1.867AlaHis: 1.867 ± 0.46
3.024AlaIle: 3.024 ± 0.507
1.245AlaLys: 1.245 ± 0.342
9.693AlaLeu: 9.693 ± 1.401
1.601AlaMet: 1.601 ± 0.346
3.024AlaAsn: 3.024 ± 0.741
6.136AlaPro: 6.136 ± 0.734
3.557AlaGln: 3.557 ± 0.673
7.47AlaArg: 7.47 ± 0.976
5.247AlaSer: 5.247 ± 0.696
5.602AlaThr: 5.602 ± 0.981
6.225AlaVal: 6.225 ± 1.036
1.067AlaTrp: 1.067 ± 0.253
3.913AlaTyr: 3.913 ± 0.505
0.0AlaXaa: 0.0 ± 0.0
Cys
1.601CysAla: 1.601 ± 0.382
0.8CysCys: 0.8 ± 0.352
0.889CysAsp: 0.889 ± 0.284
0.978CysGlu: 0.978 ± 0.324
0.534CysPhe: 0.534 ± 0.307
1.334CysGly: 1.334 ± 0.43
0.8CysHis: 0.8 ± 0.23
0.445CysIle: 0.445 ± 0.206
0.445CysLys: 0.445 ± 0.24
2.223CysLeu: 2.223 ± 0.475
0.356CysMet: 0.356 ± 0.189
0.622CysAsn: 0.622 ± 0.219
0.978CysPro: 0.978 ± 0.289
0.534CysGln: 0.534 ± 0.244
1.067CysArg: 1.067 ± 0.368
1.156CysSer: 1.156 ± 0.374
1.067CysThr: 1.067 ± 0.319
1.156CysVal: 1.156 ± 0.424
0.356CysTrp: 0.356 ± 0.209
1.245CysTyr: 1.245 ± 0.312
0.0CysXaa: 0.0 ± 0.0
Asp
3.557AspAla: 3.557 ± 0.939
1.067AspCys: 1.067 ± 0.436
1.867AspAsp: 1.867 ± 0.394
3.468AspGlu: 3.468 ± 0.534
1.601AspPhe: 1.601 ± 0.315
2.846AspGly: 2.846 ± 0.381
1.156AspHis: 1.156 ± 0.318
1.156AspIle: 1.156 ± 0.294
1.334AspLys: 1.334 ± 0.309
5.069AspLeu: 5.069 ± 0.898
1.156AspMet: 1.156 ± 0.37
2.045AspAsn: 2.045 ± 0.37
3.379AspPro: 3.379 ± 0.487
0.8AspGln: 0.8 ± 0.273
3.646AspArg: 3.646 ± 0.806
3.735AspSer: 3.735 ± 0.859
1.956AspThr: 1.956 ± 0.558
3.112AspVal: 3.112 ± 0.754
0.445AspTrp: 0.445 ± 0.179
2.223AspTyr: 2.223 ± 0.331
0.0AspXaa: 0.0 ± 0.0
Glu
5.602GluAla: 5.602 ± 1.157
0.711GluCys: 0.711 ± 0.266
3.468GluAsp: 3.468 ± 0.505
6.492GluGlu: 6.492 ± 1.315
1.956GluPhe: 1.956 ± 0.302
4.091GluGly: 4.091 ± 0.768
1.067GluHis: 1.067 ± 0.373
1.779GluIle: 1.779 ± 0.255
1.956GluLys: 1.956 ± 0.422
5.869GluLeu: 5.869 ± 1.111
0.622GluMet: 0.622 ± 0.26
2.312GluAsn: 2.312 ± 0.447
3.024GluPro: 3.024 ± 0.552
3.201GluGln: 3.201 ± 0.571
4.713GluArg: 4.713 ± 1.022
2.935GluSer: 2.935 ± 0.493
2.401GluThr: 2.401 ± 0.468
4.624GluVal: 4.624 ± 0.723
0.889GluTrp: 0.889 ± 0.242
1.156GluTyr: 1.156 ± 0.338
0.0GluXaa: 0.0 ± 0.0
Phe
2.49PheAla: 2.49 ± 0.488
0.534PheCys: 0.534 ± 0.222
2.401PheAsp: 2.401 ± 0.513
2.401PheGlu: 2.401 ± 0.497
1.867PhePhe: 1.867 ± 0.462
0.889PheGly: 0.889 ± 0.258
0.978PheHis: 0.978 ± 0.292
1.512PheIle: 1.512 ± 0.423
1.423PheLys: 1.423 ± 0.366
2.935PheLeu: 2.935 ± 0.671
1.334PheMet: 1.334 ± 0.302
2.223PheAsn: 2.223 ± 0.493
1.69PhePro: 1.69 ± 0.465
1.601PheGln: 1.601 ± 0.331
2.757PheArg: 2.757 ± 0.525
2.846PheSer: 2.846 ± 0.52
1.779PheThr: 1.779 ± 0.389
3.112PheVal: 3.112 ± 0.441
0.178PheTrp: 0.178 ± 0.125
1.779PheTyr: 1.779 ± 0.359
0.0PheXaa: 0.0 ± 0.0
Gly
5.602GlyAla: 5.602 ± 0.859
0.978GlyCys: 0.978 ± 0.287
3.112GlyAsp: 3.112 ± 0.375
3.557GlyGlu: 3.557 ± 0.725
2.134GlyPhe: 2.134 ± 0.389
4.891GlyGly: 4.891 ± 0.919
1.601GlyHis: 1.601 ± 0.493
2.045GlyIle: 2.045 ± 0.44
1.245GlyLys: 1.245 ± 0.391
7.47GlyLeu: 7.47 ± 1.309
1.067GlyMet: 1.067 ± 0.311
1.601GlyAsn: 1.601 ± 0.642
4.269GlyPro: 4.269 ± 0.612
2.846GlyGln: 2.846 ± 0.491
5.336GlyArg: 5.336 ± 0.821
3.913GlySer: 3.913 ± 0.642
2.935GlyThr: 2.935 ± 0.544
4.802GlyVal: 4.802 ± 0.839
0.889GlyTrp: 0.889 ± 0.287
1.867GlyTyr: 1.867 ± 0.467
0.0GlyXaa: 0.0 ± 0.0
His
1.779HisAla: 1.779 ± 0.514
0.711HisCys: 0.711 ± 0.374
0.711HisAsp: 0.711 ± 0.3
1.156HisGlu: 1.156 ± 0.264
0.711HisPhe: 0.711 ± 0.269
2.223HisGly: 2.223 ± 0.539
0.622HisHis: 0.622 ± 0.274
0.445HisIle: 0.445 ± 0.226
0.711HisLys: 0.711 ± 0.237
3.112HisLeu: 3.112 ± 0.609
0.267HisMet: 0.267 ± 0.149
1.512HisAsn: 1.512 ± 0.29
2.045HisPro: 2.045 ± 0.41
1.156HisGln: 1.156 ± 0.356
2.045HisArg: 2.045 ± 0.444
1.067HisSer: 1.067 ± 0.362
1.245HisThr: 1.245 ± 0.32
1.601HisVal: 1.601 ± 0.429
0.356HisTrp: 0.356 ± 0.224
0.445HisTyr: 0.445 ± 0.165
0.0HisXaa: 0.0 ± 0.0
Ile
2.223IleAla: 2.223 ± 0.521
0.8IleCys: 0.8 ± 0.323
0.889IleAsp: 0.889 ± 0.343
1.156IleGlu: 1.156 ± 0.343
1.156IlePhe: 1.156 ± 0.402
2.134IleGly: 2.134 ± 0.568
0.445IleHis: 0.445 ± 0.271
0.8IleIle: 0.8 ± 0.304
1.867IleLys: 1.867 ± 0.407
2.935IleLeu: 2.935 ± 0.523
0.711IleMet: 0.711 ± 0.216
1.69IleAsn: 1.69 ± 0.337
1.601IlePro: 1.601 ± 0.446
1.245IleGln: 1.245 ± 0.345
1.779IleArg: 1.779 ± 0.382
2.579IleSer: 2.579 ± 0.424
1.69IleThr: 1.69 ± 0.336
2.312IleVal: 2.312 ± 0.333
0.0IleTrp: 0.0 ± 0.0
1.067IleTyr: 1.067 ± 0.359
0.0IleXaa: 0.0 ± 0.0
Lys
2.401LysAla: 2.401 ± 0.361
0.445LysCys: 0.445 ± 0.2
1.245LysAsp: 1.245 ± 0.443
1.956LysGlu: 1.956 ± 0.437
0.978LysPhe: 0.978 ± 0.284
2.134LysGly: 2.134 ± 0.465
0.8LysHis: 0.8 ± 0.271
1.423LysIle: 1.423 ± 0.391
1.779LysLys: 1.779 ± 0.487
2.401LysLeu: 2.401 ± 0.555
0.622LysMet: 0.622 ± 0.223
1.334LysAsn: 1.334 ± 0.302
1.779LysPro: 1.779 ± 0.575
1.067LysGln: 1.067 ± 0.29
2.935LysArg: 2.935 ± 0.699
1.156LysSer: 1.156 ± 0.317
1.156LysThr: 1.156 ± 0.291
2.045LysVal: 2.045 ± 0.396
0.267LysTrp: 0.267 ± 0.172
0.711LysTyr: 0.711 ± 0.328
0.0LysXaa: 0.0 ± 0.0
Leu
10.049LeuAla: 10.049 ± 1.363
2.223LeuCys: 2.223 ± 0.668
4.357LeuAsp: 4.357 ± 0.84
5.069LeuGlu: 5.069 ± 0.682
2.579LeuPhe: 2.579 ± 0.642
6.67LeuGly: 6.67 ± 0.962
3.557LeuHis: 3.557 ± 0.61
3.468LeuIle: 3.468 ± 0.667
3.735LeuLys: 3.735 ± 0.639
10.582LeuLeu: 10.582 ± 1.198
2.846LeuMet: 2.846 ± 0.469
3.735LeuAsn: 3.735 ± 0.525
7.559LeuPro: 7.559 ± 0.905
5.691LeuGln: 5.691 ± 0.961
9.16LeuArg: 9.16 ± 1.215
7.292LeuSer: 7.292 ± 1.089
8.982LeuThr: 8.982 ± 2.148
5.425LeuVal: 5.425 ± 0.927
2.134LeuTrp: 2.134 ± 0.396
3.468LeuTyr: 3.468 ± 0.71
0.0LeuXaa: 0.0 ± 0.0
Met
2.49MetAla: 2.49 ± 0.516
0.178MetCys: 0.178 ± 0.11
1.334MetAsp: 1.334 ± 0.352
1.156MetGlu: 1.156 ± 0.334
0.8MetPhe: 0.8 ± 0.3
1.423MetGly: 1.423 ± 0.384
0.889MetHis: 0.889 ± 0.286
0.622MetIle: 0.622 ± 0.185
0.8MetLys: 0.8 ± 0.296
1.956MetLeu: 1.956 ± 0.558
0.356MetMet: 0.356 ± 0.165
0.8MetAsn: 0.8 ± 0.265
1.69MetPro: 1.69 ± 0.414
1.156MetGln: 1.156 ± 0.335
1.423MetArg: 1.423 ± 0.4
1.156MetSer: 1.156 ± 0.342
0.622MetThr: 0.622 ± 0.251
0.978MetVal: 0.978 ± 0.322
0.267MetTrp: 0.267 ± 0.18
0.889MetTyr: 0.889 ± 0.273
0.0MetXaa: 0.0 ± 0.0
Asn
2.49AsnAla: 2.49 ± 0.639
0.711AsnCys: 0.711 ± 0.235
1.956AsnAsp: 1.956 ± 0.487
1.423AsnGlu: 1.423 ± 0.357
2.668AsnPhe: 2.668 ± 0.587
1.601AsnGly: 1.601 ± 0.36
1.067AsnHis: 1.067 ± 0.336
1.423AsnIle: 1.423 ± 0.475
0.889AsnLys: 0.889 ± 0.287
3.913AsnLeu: 3.913 ± 0.667
1.512AsnMet: 1.512 ± 0.512
0.978AsnAsn: 0.978 ± 0.368
3.468AsnPro: 3.468 ± 0.562
1.423AsnGln: 1.423 ± 0.268
2.401AsnArg: 2.401 ± 0.528
3.201AsnSer: 3.201 ± 0.869
1.867AsnThr: 1.867 ± 0.499
2.134AsnVal: 2.134 ± 0.463
0.534AsnTrp: 0.534 ± 0.216
2.134AsnTyr: 2.134 ± 0.564
0.0AsnXaa: 0.0 ± 0.0
Pro
5.869ProAla: 5.869 ± 0.728
0.889ProCys: 0.889 ± 0.431
3.735ProAsp: 3.735 ± 0.502
5.336ProGlu: 5.336 ± 0.881
2.846ProPhe: 2.846 ± 0.649
4.713ProGly: 4.713 ± 0.641
1.423ProHis: 1.423 ± 0.362
0.8ProIle: 0.8 ± 0.273
1.867ProLys: 1.867 ± 0.427
8.004ProLeu: 8.004 ± 1.351
0.889ProMet: 0.889 ± 0.367
1.956ProAsn: 1.956 ± 0.452
11.561ProPro: 11.561 ± 2.444
3.646ProGln: 3.646 ± 0.824
5.869ProArg: 5.869 ± 1.023
5.158ProSer: 5.158 ± 0.605
3.735ProThr: 3.735 ± 0.754
4.802ProVal: 4.802 ± 0.978
0.622ProTrp: 0.622 ± 0.259
2.134ProTyr: 2.134 ± 0.526
0.0ProXaa: 0.0 ± 0.0
Gln
4.357GlnAla: 4.357 ± 0.808
1.156GlnCys: 1.156 ± 0.377
1.334GlnAsp: 1.334 ± 0.392
2.846GlnGlu: 2.846 ± 0.593
1.156GlnPhe: 1.156 ± 0.299
2.668GlnGly: 2.668 ± 0.692
0.978GlnHis: 0.978 ± 0.279
1.423GlnIle: 1.423 ± 0.426
1.245GlnLys: 1.245 ± 0.337
5.958GlnLeu: 5.958 ± 0.764
0.978GlnMet: 0.978 ± 0.216
1.779GlnAsn: 1.779 ± 0.46
4.002GlnPro: 4.002 ± 0.452
1.601GlnGln: 1.601 ± 0.396
3.468GlnArg: 3.468 ± 0.584
3.379GlnSer: 3.379 ± 0.736
2.223GlnThr: 2.223 ± 0.485
3.201GlnVal: 3.201 ± 0.584
0.356GlnTrp: 0.356 ± 0.173
0.711GlnTyr: 0.711 ± 0.191
0.0GlnXaa: 0.0 ± 0.0
Arg
8.181ArgAla: 8.181 ± 1.299
1.601ArgCys: 1.601 ± 0.434
3.468ArgAsp: 3.468 ± 0.756
4.535ArgGlu: 4.535 ± 0.996
2.846ArgPhe: 2.846 ± 0.445
5.78ArgGly: 5.78 ± 0.722
1.69ArgHis: 1.69 ± 0.414
1.334ArgIle: 1.334 ± 0.319
2.312ArgLys: 2.312 ± 0.429
8.537ArgLeu: 8.537 ± 1.343
1.156ArgMet: 1.156 ± 0.341
3.024ArgAsn: 3.024 ± 0.608
4.802ArgPro: 4.802 ± 0.951
4.891ArgGln: 4.891 ± 0.729
10.494ArgArg: 10.494 ± 2.169
4.624ArgSer: 4.624 ± 0.81
2.579ArgThr: 2.579 ± 0.527
4.891ArgVal: 4.891 ± 0.859
1.601ArgTrp: 1.601 ± 0.307
2.045ArgTyr: 2.045 ± 0.532
0.0ArgXaa: 0.0 ± 0.0
Ser
6.492SerAla: 6.492 ± 0.713
1.067SerCys: 1.067 ± 0.472
2.668SerAsp: 2.668 ± 0.409
3.379SerGlu: 3.379 ± 0.415
2.401SerPhe: 2.401 ± 0.464
4.624SerGly: 4.624 ± 0.907
1.69SerHis: 1.69 ± 0.472
2.045SerIle: 2.045 ± 0.499
1.512SerLys: 1.512 ± 0.316
8.004SerLeu: 8.004 ± 1.164
1.067SerMet: 1.067 ± 0.398
2.223SerAsn: 2.223 ± 0.442
5.514SerPro: 5.514 ± 0.857
2.935SerGln: 2.935 ± 0.468
4.624SerArg: 4.624 ± 0.64
4.535SerSer: 4.535 ± 1.093
3.735SerThr: 3.735 ± 0.643
4.091SerVal: 4.091 ± 0.694
0.978SerTrp: 0.978 ± 0.329
2.401SerTyr: 2.401 ± 0.525
0.0SerXaa: 0.0 ± 0.0
Thr
5.069ThrAla: 5.069 ± 1.006
0.889ThrCys: 0.889 ± 0.252
2.045ThrAsp: 2.045 ± 0.444
1.779ThrGlu: 1.779 ± 0.337
2.312ThrPhe: 2.312 ± 0.467
3.024ThrGly: 3.024 ± 0.634
0.978ThrHis: 0.978 ± 0.269
1.779ThrIle: 1.779 ± 0.341
0.8ThrLys: 0.8 ± 0.273
7.47ThrLeu: 7.47 ± 1.004
1.156ThrMet: 1.156 ± 0.367
2.134ThrAsn: 2.134 ± 0.686
4.713ThrPro: 4.713 ± 0.861
1.779ThrGln: 1.779 ± 0.487
2.668ThrArg: 2.668 ± 0.463
3.29ThrSer: 3.29 ± 0.785
4.091ThrThr: 4.091 ± 0.895
4.713ThrVal: 4.713 ± 0.751
1.156ThrTrp: 1.156 ± 0.302
2.223ThrTyr: 2.223 ± 0.557
0.0ThrXaa: 0.0 ± 0.0
Val
5.336ValAla: 5.336 ± 0.842
1.423ValCys: 1.423 ± 0.506
4.002ValAsp: 4.002 ± 0.658
4.002ValGlu: 4.002 ± 0.845
2.846ValPhe: 2.846 ± 0.417
2.579ValGly: 2.579 ± 0.568
1.067ValHis: 1.067 ± 0.408
2.134ValIle: 2.134 ± 0.543
2.134ValLys: 2.134 ± 0.544
6.936ValLeu: 6.936 ± 0.873
1.867ValMet: 1.867 ± 0.388
2.401ValAsn: 2.401 ± 0.427
4.624ValPro: 4.624 ± 0.562
3.201ValGln: 3.201 ± 0.631
5.069ValArg: 5.069 ± 0.912
5.247ValSer: 5.247 ± 0.79
3.824ValThr: 3.824 ± 0.742
4.357ValVal: 4.357 ± 1.092
0.622ValTrp: 0.622 ± 0.258
3.379ValTyr: 3.379 ± 0.613
0.0ValXaa: 0.0 ± 0.0
Trp
0.267TrpAla: 0.267 ± 0.136
0.178TrpCys: 0.178 ± 0.128
0.622TrpAsp: 0.622 ± 0.208
1.245TrpGlu: 1.245 ± 0.365
0.267TrpPhe: 0.267 ± 0.151
1.512TrpGly: 1.512 ± 0.342
0.089TrpHis: 0.089 ± 0.09
0.534TrpIle: 0.534 ± 0.235
0.356TrpLys: 0.356 ± 0.165
1.512TrpLeu: 1.512 ± 0.373
0.267TrpMet: 0.267 ± 0.139
0.889TrpAsn: 0.889 ± 0.373
0.8TrpPro: 0.8 ± 0.232
0.889TrpGln: 0.889 ± 0.326
0.889TrpArg: 0.889 ± 0.29
1.245TrpSer: 1.245 ± 0.333
0.711TrpThr: 0.711 ± 0.268
0.534TrpVal: 0.534 ± 0.202
0.267TrpTrp: 0.267 ± 0.124
0.267TrpTyr: 0.267 ± 0.161
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.757TyrAla: 2.757 ± 0.547
0.889TyrCys: 0.889 ± 0.317
1.69TyrAsp: 1.69 ± 0.496
1.956TyrGlu: 1.956 ± 0.519
1.779TyrPhe: 1.779 ± 0.391
1.601TyrGly: 1.601 ± 0.436
1.156TyrHis: 1.156 ± 0.383
0.889TyrIle: 0.889 ± 0.327
0.978TyrLys: 0.978 ± 0.376
4.002TyrLeu: 4.002 ± 0.661
1.067TyrMet: 1.067 ± 0.328
1.512TyrAsn: 1.512 ± 0.49
2.223TyrPro: 2.223 ± 0.61
1.601TyrGln: 1.601 ± 0.432
2.579TyrArg: 2.579 ± 0.47
2.223TyrSer: 2.223 ± 0.511
1.867TyrThr: 1.867 ± 0.325
2.935TyrVal: 2.935 ± 0.617
0.356TyrTrp: 0.356 ± 0.17
0.889TyrTyr: 0.889 ± 0.416
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 32 proteins (11246 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski