Amino acid dipepetide frequency for Haloglomus irregulare

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.966AlaAla: 15.966 ± 0.199	0.832AlaCys: 0.832 ± 0.031	10.896AlaAsp: 10.896 ± 0.124	9.181AlaGlu: 9.181 ± 0.114	4.016AlaPhe: 4.016 ± 0.068	11.378AlaGly: 11.378 ± 0.121	1.985AlaHis: 1.985 ± 0.045	3.962AlaIle: 3.962 ± 0.068	1.497AlaLys: 1.497 ± 0.04	10.9AlaLeu: 10.9 ± 0.137	2.041AlaMet: 2.041 ± 0.052	2.323AlaAsn: 2.323 ± 0.051	4.948AlaPro: 4.948 ± 0.072	2.066AlaGln: 2.066 ± 0.045	7.368AlaArg: 7.368 ± 0.096	5.216AlaSer: 5.216 ± 0.076	7.822AlaThr: 7.822 ± 0.1	11.699AlaVal: 11.699 ± 0.15	1.103AlaTrp: 1.103 ± 0.034	2.702AlaTyr: 2.702 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.688CysAla: 0.688 ± 0.025	0.118CysCys: 0.118 ± 0.011	0.629CysAsp: 0.629 ± 0.025	0.615CysGlu: 0.615 ± 0.026	0.204CysPhe: 0.204 ± 0.014	0.932CysGly: 0.932 ± 0.034	0.199CysHis: 0.199 ± 0.013	0.272CysIle: 0.272 ± 0.018	0.114CysLys: 0.114 ± 0.011	0.528CysLeu: 0.528 ± 0.024	0.12CysMet: 0.12 ± 0.011	0.201CysAsn: 0.201 ± 0.014	0.574CysPro: 0.574 ± 0.027	0.166CysGln: 0.166 ± 0.013	0.538CysArg: 0.538 ± 0.023	0.447CysSer: 0.447 ± 0.023	0.423CysThr: 0.423 ± 0.021	0.475CysVal: 0.475 ± 0.02	0.111CysTrp: 0.111 ± 0.012	0.236CysTyr: 0.236 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	10.409AspAla: 10.409 ± 0.119	0.807AspCys: 0.807 ± 0.032	7.404AspAsp: 7.404 ± 0.117	7.295AspGlu: 7.295 ± 0.107	1.742AspPhe: 1.742 ± 0.044	9.451AspGly: 9.451 ± 0.117	1.911AspHis: 1.911 ± 0.053	3.1AspIle: 3.1 ± 0.059	0.741AspLys: 0.741 ± 0.028	7.175AspLeu: 7.175 ± 0.085	1.326AspMet: 1.326 ± 0.036	1.141AspAsn: 1.141 ± 0.038	5.372AspPro: 5.372 ± 0.079	1.539AspGln: 1.539 ± 0.043	7.436AspArg: 7.436 ± 0.09	3.363AspSer: 3.363 ± 0.065	4.347AspThr: 4.347 ± 0.066	6.779AspVal: 6.779 ± 0.091	1.112AspTrp: 1.112 ± 0.035	1.907AspTyr: 1.907 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	9.394GluAla: 9.394 ± 0.138	0.546GluCys: 0.546 ± 0.027	5.225GluAsp: 5.225 ± 0.094	5.724GluGlu: 5.724 ± 0.112	2.857GluPhe: 2.857 ± 0.052	5.933GluGly: 5.933 ± 0.087	1.933GluHis: 1.933 ± 0.048	2.751GluIle: 2.751 ± 0.065	1.395GluLys: 1.395 ± 0.042	7.279GluLeu: 7.279 ± 0.098	1.66GluMet: 1.66 ± 0.038	1.814GluAsn: 1.814 ± 0.045	4.309GluPro: 4.309 ± 0.073	2.564GluGln: 2.564 ± 0.057	8.176GluArg: 8.176 ± 0.112	4.387GluSer: 4.387 ± 0.074	6.005GluThr: 6.005 ± 0.08	5.904GluVal: 5.904 ± 0.09	1.059GluTrp: 1.059 ± 0.036	2.22GluTyr: 2.22 ± 0.053	0.0GluXaa: 0.0 ± 0.0
Phe	3.655PheAla: 3.655 ± 0.065	0.305PheCys: 0.305 ± 0.018	3.257PheAsp: 3.257 ± 0.049	2.866PheGlu: 2.866 ± 0.057	0.836PhePhe: 0.836 ± 0.035	3.298PheGly: 3.298 ± 0.07	0.589PheHis: 0.589 ± 0.021	0.983PheIle: 0.983 ± 0.03	0.417PheLys: 0.417 ± 0.02	2.565PheLeu: 2.565 ± 0.056	0.461PheMet: 0.461 ± 0.022	0.613PheAsn: 0.613 ± 0.024	1.28PhePro: 1.28 ± 0.036	0.763PheGln: 0.763 ± 0.028	2.023PheArg: 2.023 ± 0.052	1.46PheSer: 1.46 ± 0.041	1.763PheThr: 1.763 ± 0.042	2.884PheVal: 2.884 ± 0.065	0.347PheTrp: 0.347 ± 0.019	0.784PheTyr: 0.784 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.712GlyAla: 9.712 ± 0.125	0.707GlyCys: 0.707 ± 0.027	7.561GlyAsp: 7.561 ± 0.092	7.363GlyGlu: 7.363 ± 0.087	3.146GlyPhe: 3.146 ± 0.062	8.947GlyGly: 8.947 ± 0.157	1.851GlyHis: 1.851 ± 0.046	3.634GlyIle: 3.634 ± 0.067	1.556GlyLys: 1.556 ± 0.041	8.079GlyLeu: 8.079 ± 0.126	1.77GlyMet: 1.77 ± 0.044	1.939GlyAsn: 1.939 ± 0.054	4.312GlyPro: 4.312 ± 0.074	2.047GlyGln: 2.047 ± 0.043	6.111GlyArg: 6.111 ± 0.074	5.485GlySer: 5.485 ± 0.086	6.809GlyThr: 6.809 ± 0.1	8.0GlyVal: 8.0 ± 0.111	1.147GlyTrp: 1.147 ± 0.034	2.595GlyTyr: 2.595 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.107HisAla: 2.107 ± 0.046	0.177HisCys: 0.177 ± 0.013	1.883HisAsp: 1.883 ± 0.048	1.81HisGlu: 1.81 ± 0.044	0.464HisPhe: 0.464 ± 0.019	2.088HisGly: 2.088 ± 0.046	0.541HisHis: 0.541 ± 0.026	0.651HisIle: 0.651 ± 0.025	0.262HisLys: 0.262 ± 0.017	1.665HisLeu: 1.665 ± 0.046	0.257HisMet: 0.257 ± 0.017	0.442HisAsn: 0.442 ± 0.023	1.286HisPro: 1.286 ± 0.036	0.453HisGln: 0.453 ± 0.018	1.464HisArg: 1.464 ± 0.039	0.853HisSer: 0.853 ± 0.028	1.098HisThr: 1.098 ± 0.031	1.895HisVal: 1.895 ± 0.045	0.219HisTrp: 0.219 ± 0.014	0.537HisTyr: 0.537 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	3.887IleAla: 3.887 ± 0.065	0.221IleCys: 0.221 ± 0.015	3.295IleAsp: 3.295 ± 0.064	3.514IleGlu: 3.514 ± 0.066	0.612IlePhe: 0.612 ± 0.028	3.266IleGly: 3.266 ± 0.066	0.675IleHis: 0.675 ± 0.026	1.14IleIle: 1.14 ± 0.038	0.55IleLys: 0.55 ± 0.024	2.137IleLeu: 2.137 ± 0.054	0.404IleMet: 0.404 ± 0.019	0.862IleAsn: 0.862 ± 0.032	1.7IlePro: 1.7 ± 0.044	0.88IleGln: 0.88 ± 0.031	2.33IleArg: 2.33 ± 0.052	1.715IleSer: 1.715 ± 0.044	2.045IleThr: 2.045 ± 0.05	2.912IleVal: 2.912 ± 0.059	0.236IleTrp: 0.236 ± 0.015	0.711IleTyr: 0.711 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	1.503LysAla: 1.503 ± 0.039	0.096LysCys: 0.096 ± 0.009	0.788LysAsp: 0.788 ± 0.026	1.09LysGlu: 1.09 ± 0.039	0.431LysPhe: 0.431 ± 0.021	1.166LysGly: 1.166 ± 0.041	0.382LysHis: 0.382 ± 0.019	0.595LysIle: 0.595 ± 0.023	0.402LysLys: 0.402 ± 0.023	1.484LysLeu: 1.484 ± 0.039	0.28LysMet: 0.28 ± 0.019	0.397LysAsn: 0.397 ± 0.021	0.808LysPro: 0.808 ± 0.03	0.682LysGln: 0.682 ± 0.029	1.45LysArg: 1.45 ± 0.042	0.86LysSer: 0.86 ± 0.033	1.048LysThr: 1.048 ± 0.029	0.935LysVal: 0.935 ± 0.03	0.193LysTrp: 0.193 ± 0.013	0.474LysTyr: 0.474 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	11.793LeuAla: 11.793 ± 0.147	0.594LeuCys: 0.594 ± 0.023	7.711LeuAsp: 7.711 ± 0.092	6.202LeuGlu: 6.202 ± 0.084	2.869LeuPhe: 2.869 ± 0.062	7.831LeuGly: 7.831 ± 0.126	1.657LeuHis: 1.657 ± 0.041	2.282LeuIle: 2.282 ± 0.057	1.413LeuLys: 1.413 ± 0.036	8.543LeuLeu: 8.543 ± 0.137	1.272LeuMet: 1.272 ± 0.036	1.741LeuAsn: 1.741 ± 0.04	4.635LeuPro: 4.635 ± 0.069	1.985LeuGln: 1.985 ± 0.042	6.238LeuArg: 6.238 ± 0.072	5.151LeuSer: 5.151 ± 0.067	5.445LeuThr: 5.445 ± 0.074	8.636LeuVal: 8.636 ± 0.115	0.772LeuTrp: 0.772 ± 0.029	1.974LeuTyr: 1.974 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	1.891MetAla: 1.891 ± 0.049	0.122MetCys: 0.122 ± 0.01	1.265MetAsp: 1.265 ± 0.033	1.142MetGlu: 1.142 ± 0.037	0.442MetPhe: 0.442 ± 0.023	1.367MetGly: 1.367 ± 0.041	0.326MetHis: 0.326 ± 0.018	0.501MetIle: 0.501 ± 0.022	0.333MetLys: 0.333 ± 0.018	1.443MetLeu: 1.443 ± 0.039	0.273MetMet: 0.273 ± 0.018	0.482MetAsn: 0.482 ± 0.02	0.82MetPro: 0.82 ± 0.029	0.449MetGln: 0.449 ± 0.022	1.167MetArg: 1.167 ± 0.035	1.475MetSer: 1.475 ± 0.035	1.486MetThr: 1.486 ± 0.039	1.164MetVal: 1.164 ± 0.032	0.12MetTrp: 0.12 ± 0.009	0.347MetTyr: 0.347 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.408AsnAla: 2.408 ± 0.046	0.196AsnCys: 0.196 ± 0.015	1.594AsnAsp: 1.594 ± 0.042	1.609AsnGlu: 1.609 ± 0.047	0.592AsnPhe: 0.592 ± 0.027	1.978AsnGly: 1.978 ± 0.053	0.447AsnHis: 0.447 ± 0.02	0.76AsnIle: 0.76 ± 0.026	0.343AsnLys: 0.343 ± 0.021	1.71AsnLeu: 1.71 ± 0.043	0.379AsnMet: 0.379 ± 0.019	0.512AsnAsn: 0.512 ± 0.027	1.374AsnPro: 1.374 ± 0.043	0.562AsnGln: 0.562 ± 0.026	1.58AsnArg: 1.58 ± 0.04	0.929AsnSer: 0.929 ± 0.035	1.26AsnThr: 1.26 ± 0.042	2.001AsnVal: 2.001 ± 0.048	0.282AsnTrp: 0.282 ± 0.016	0.564AsnTyr: 0.564 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.03ProAla: 6.03 ± 0.085	0.272ProCys: 0.272 ± 0.017	5.542ProAsp: 5.542 ± 0.078	4.844ProGlu: 4.844 ± 0.068	1.607ProPhe: 1.607 ± 0.038	4.925ProGly: 4.925 ± 0.075	0.911ProHis: 0.911 ± 0.032	1.416ProIle: 1.416 ± 0.038	0.704ProLys: 0.704 ± 0.027	3.984ProLeu: 3.984 ± 0.061	0.831ProMet: 0.831 ± 0.03	1.038ProAsn: 1.038 ± 0.038	2.738ProPro: 2.738 ± 0.064	0.933ProGln: 0.933 ± 0.032	2.837ProArg: 2.837 ± 0.05	2.688ProSer: 2.688 ± 0.049	3.595ProThr: 3.595 ± 0.071	4.724ProVal: 4.724 ± 0.072	0.512ProTrp: 0.512 ± 0.02	1.105ProTyr: 1.105 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.413GlnAla: 2.413 ± 0.048	0.165GlnCys: 0.165 ± 0.013	1.292GlnAsp: 1.292 ± 0.033	1.611GlnGlu: 1.611 ± 0.052	0.963GlnPhe: 0.963 ± 0.025	1.733GlnGly: 1.733 ± 0.047	0.545GlnHis: 0.545 ± 0.024	0.783GlnIle: 0.783 ± 0.031	0.484GlnLys: 0.484 ± 0.026	2.312GlnLeu: 2.312 ± 0.052	0.414GlnMet: 0.414 ± 0.02	0.592GlnAsn: 0.592 ± 0.029	1.268GlnPro: 1.268 ± 0.039	1.037GlnGln: 1.037 ± 0.045	2.088GlnArg: 2.088 ± 0.045	1.402GlnSer: 1.402 ± 0.035	1.31GlnThr: 1.31 ± 0.037	1.962GlnVal: 1.962 ± 0.045	0.28GlnTrp: 0.28 ± 0.014	0.785GlnTyr: 0.785 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	8.057ArgAla: 8.057 ± 0.1	0.565ArgCys: 0.565 ± 0.021	5.552ArgAsp: 5.552 ± 0.079	7.091ArgGlu: 7.091 ± 0.091	2.594ArgPhe: 2.594 ± 0.055	5.259ArgGly: 5.259 ± 0.077	1.422ArgHis: 1.422 ± 0.037	2.568ArgIle: 2.568 ± 0.05	1.286ArgLys: 1.286 ± 0.036	7.064ArgLeu: 7.064 ± 0.088	1.389ArgMet: 1.389 ± 0.036	1.71ArgAsn: 1.71 ± 0.046	3.215ArgPro: 3.215 ± 0.064	1.894ArgGln: 1.894 ± 0.048	5.906ArgArg: 5.906 ± 0.107	3.712ArgSer: 3.712 ± 0.055	4.602ArgThr: 4.602 ± 0.072	6.401ArgVal: 6.401 ± 0.086	0.895ArgTrp: 0.895 ± 0.029	2.115ArgTyr: 2.115 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	5.155SerAla: 5.155 ± 0.086	0.369SerCys: 0.369 ± 0.022	4.072SerAsp: 4.072 ± 0.079	3.896SerGlu: 3.896 ± 0.062	1.785SerPhe: 1.785 ± 0.044	5.422SerGly: 5.422 ± 0.092	0.995SerHis: 0.995 ± 0.028	1.84SerIle: 1.84 ± 0.05	0.937SerLys: 0.937 ± 0.03	4.632SerLeu: 4.632 ± 0.069	0.949SerMet: 0.949 ± 0.029	1.152SerAsn: 1.152 ± 0.039	2.598SerPro: 2.598 ± 0.054	1.22SerGln: 1.22 ± 0.041	3.324SerArg: 3.324 ± 0.056	2.708SerSer: 2.708 ± 0.065	3.281SerThr: 3.281 ± 0.066	4.623SerVal: 4.623 ± 0.076	0.535SerTrp: 0.535 ± 0.022	1.388SerTyr: 1.388 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	7.84ThrAla: 7.84 ± 0.108	0.405ThrCys: 0.405 ± 0.02	5.759ThrAsp: 5.759 ± 0.089	4.637ThrGlu: 4.637 ± 0.07	2.064ThrPhe: 2.064 ± 0.046	6.497ThrGly: 6.497 ± 0.099	1.212ThrHis: 1.212 ± 0.033	2.116ThrIle: 2.116 ± 0.043	0.825ThrLys: 0.825 ± 0.028	5.798ThrLeu: 5.798 ± 0.082	0.982ThrMet: 0.982 ± 0.031	1.398ThrAsn: 1.398 ± 0.038	3.698ThrPro: 3.698 ± 0.064	1.222ThrGln: 1.222 ± 0.034	3.809ThrArg: 3.809 ± 0.062	2.844ThrSer: 2.844 ± 0.061	4.583ThrThr: 4.583 ± 0.076	7.496ThrVal: 7.496 ± 0.112	0.564ThrTrp: 0.564 ± 0.021	1.589ThrTyr: 1.589 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	11.277ValAla: 11.277 ± 0.142	0.747ValCys: 0.747 ± 0.029	7.477ValAsp: 7.477 ± 0.096	7.666ValGlu: 7.666 ± 0.1	2.789ValPhe: 2.789 ± 0.056	8.237ValGly: 8.237 ± 0.103	1.726ValHis: 1.726 ± 0.041	2.744ValIle: 2.744 ± 0.064	1.21ValLys: 1.21 ± 0.033	7.978ValLeu: 7.978 ± 0.106	1.244ValMet: 1.244 ± 0.034	1.851ValAsn: 1.851 ± 0.04	4.637ValPro: 4.637 ± 0.077	1.908ValGln: 1.908 ± 0.046	6.416ValArg: 6.416 ± 0.081	4.52ValSer: 4.52 ± 0.064	6.233ValThr: 6.233 ± 0.098	8.877ValVal: 8.877 ± 0.105	0.758ValTrp: 0.758 ± 0.027	2.02ValTyr: 2.02 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	1.084TrpAla: 1.084 ± 0.033	0.102TrpCys: 0.102 ± 0.009	0.708TrpAsp: 0.708 ± 0.024	0.706TrpGlu: 0.706 ± 0.023	0.398TrpPhe: 0.398 ± 0.021	0.83TrpGly: 0.83 ± 0.028	0.209TrpHis: 0.209 ± 0.014	0.326TrpIle: 0.326 ± 0.016	0.231TrpLys: 0.231 ± 0.015	1.167TrpLeu: 1.167 ± 0.037	0.2TrpMet: 0.2 ± 0.013	0.301TrpAsn: 0.301 ± 0.017	0.459TrpPro: 0.459 ± 0.022	0.362TrpGln: 0.362 ± 0.02	0.898TrpArg: 0.898 ± 0.033	0.608TrpSer: 0.608 ± 0.027	0.776TrpThr: 0.776 ± 0.029	0.822TrpVal: 0.822 ± 0.028	0.186TrpTrp: 0.186 ± 0.014	0.347TrpTyr: 0.347 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.634TyrAla: 2.634 ± 0.054	0.241TyrCys: 0.241 ± 0.014	2.447TyrAsp: 2.447 ± 0.051	2.276TyrGlu: 2.276 ± 0.052	0.737TyrPhe: 0.737 ± 0.027	2.235TyrGly: 2.235 ± 0.053	0.639TyrHis: 0.639 ± 0.029	0.667TyrIle: 0.667 ± 0.025	0.361TyrLys: 0.361 ± 0.02	2.301TyrLeu: 2.301 ± 0.047	0.366TyrMet: 0.366 ± 0.021	0.57TyrAsn: 0.57 ± 0.026	1.206TyrPro: 1.206 ± 0.033	0.705TyrGln: 0.705 ± 0.025	2.139TyrArg: 2.139 ± 0.045	1.058TyrSer: 1.058 ± 0.033	1.406TyrThr: 1.406 ± 0.032	2.124TyrVal: 2.124 ± 0.04	0.29TyrTrp: 0.29 ± 0.018	0.734TyrTyr: 0.734 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3668 proteins (1061482 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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