Amino acid dipepetide frequency for Human associated huchismacovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.497AlaAla: 3.497 ± 2.14
0.0AlaCys: 0.0 ± 0.0
5.245AlaAsp: 5.245 ± 1.716
0.0AlaGlu: 0.0 ± 0.0
6.993AlaPhe: 6.993 ± 1.817
6.993AlaGly: 6.993 ± 4.279
1.748AlaHis: 1.748 ± 1.393
6.993AlaIle: 6.993 ± 3.108
0.0AlaLys: 0.0 ± 0.0
5.245AlaLeu: 5.245 ± 1.716
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
3.497AlaPro: 3.497 ± 0.323
3.497AlaGln: 3.497 ± 0.323
1.748AlaArg: 1.748 ± 1.07
3.497AlaSer: 3.497 ± 2.14
1.748AlaThr: 1.748 ± 1.07
1.748AlaVal: 1.748 ± 1.07
0.0AlaTrp: 0.0 ± 0.0
3.497AlaTyr: 3.497 ± 0.323
0.0AlaXaa: 0.0 ± 0.0
Cys
1.748CysAla: 1.748 ± 1.393
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.748CysGlu: 1.748 ± 1.393
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.748CysLeu: 1.748 ± 1.393
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.748CysSer: 1.748 ± 1.393
1.748CysThr: 1.748 ± 1.393
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.748AspAla: 1.748 ± 1.07
0.0AspCys: 0.0 ± 0.0
5.245AspAsp: 5.245 ± 1.716
0.0AspGlu: 0.0 ± 0.0
1.748AspPhe: 1.748 ± 1.07
1.748AspGly: 1.748 ± 1.07
1.748AspHis: 1.748 ± 1.07
5.245AspIle: 5.245 ± 4.178
1.748AspLys: 1.748 ± 1.393
8.741AspLeu: 8.741 ± 2.038
1.748AspMet: 1.748 ± 1.393
0.0AspAsn: 0.0 ± 0.0
8.741AspPro: 8.741 ± 2.887
1.748AspGln: 1.748 ± 1.07
8.741AspArg: 8.741 ± 2.038
1.748AspSer: 1.748 ± 1.07
5.245AspThr: 5.245 ± 3.209
3.497AspVal: 3.497 ± 0.323
1.748AspTrp: 1.748 ± 1.07
3.497AspTyr: 3.497 ± 2.785
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
3.497GluAsp: 3.497 ± 0.323
3.497GluGlu: 3.497 ± 0.323
1.748GluPhe: 1.748 ± 1.393
3.497GluGly: 3.497 ± 2.785
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
3.497GluLys: 3.497 ± 2.785
3.497GluLeu: 3.497 ± 2.14
1.748GluMet: 1.748 ± 1.393
8.741GluAsn: 8.741 ± 0.424
0.0GluPro: 0.0 ± 0.0
1.748GluGln: 1.748 ± 1.393
1.748GluArg: 1.748 ± 1.393
1.748GluSer: 1.748 ± 1.393
3.497GluThr: 3.497 ± 0.323
1.748GluVal: 1.748 ± 1.07
1.748GluTrp: 1.748 ± 1.393
1.748GluTyr: 1.748 ± 1.393
0.0GluXaa: 0.0 ± 0.0
Phe
1.748PheAla: 1.748 ± 1.07
0.0PheCys: 0.0 ± 0.0
3.497PheAsp: 3.497 ± 2.785
0.0PheGlu: 0.0 ± 0.0
3.497PhePhe: 3.497 ± 2.14
1.748PheGly: 1.748 ± 1.393
0.0PheHis: 0.0 ± 0.0
1.748PheIle: 1.748 ± 1.07
3.497PheLys: 3.497 ± 2.14
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
6.993PheAsn: 6.993 ± 4.279
1.748PhePro: 1.748 ± 1.07
3.497PheGln: 3.497 ± 2.14
3.497PheArg: 3.497 ± 0.323
0.0PheSer: 0.0 ± 0.0
1.748PheThr: 1.748 ± 1.393
5.245PheVal: 5.245 ± 3.209
1.748PheTrp: 1.748 ± 1.393
6.993PheTyr: 6.993 ± 4.279
0.0PheXaa: 0.0 ± 0.0
Gly
5.245GlyAla: 5.245 ± 1.716
0.0GlyCys: 0.0 ± 0.0
1.748GlyAsp: 1.748 ± 1.393
6.993GlyGlu: 6.993 ± 1.817
1.748GlyPhe: 1.748 ± 1.07
5.245GlyGly: 5.245 ± 3.209
1.748GlyHis: 1.748 ± 1.393
0.0GlyIle: 0.0 ± 0.0
5.245GlyLys: 5.245 ± 1.716
8.741GlyLeu: 8.741 ± 2.038
0.0GlyMet: 0.0 ± 0.0
6.993GlyAsn: 6.993 ± 1.817
1.748GlyPro: 1.748 ± 1.07
3.497GlyGln: 3.497 ± 2.14
1.748GlyArg: 1.748 ± 1.393
13.986GlySer: 13.986 ± 8.559
0.0GlyThr: 0.0 ± 0.0
0.0GlyVal: 0.0 ± 0.0
1.748GlyTrp: 1.748 ± 1.07
3.497GlyTyr: 3.497 ± 2.785
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.748HisIle: 1.748 ± 1.07
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.929
1.748HisAsn: 1.748 ± 1.07
0.0HisPro: 0.0 ± 0.0
1.748HisGln: 1.748 ± 1.07
0.0HisArg: 0.0 ± 0.0
1.748HisSer: 1.748 ± 1.07
0.0HisThr: 0.0 ± 0.0
1.748HisVal: 1.748 ± 1.393
0.0HisTrp: 0.0 ± 0.0
1.748HisTyr: 1.748 ± 1.393
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
8.741IleAsp: 8.741 ± 2.038
5.245IleGlu: 5.245 ± 0.747
3.497IlePhe: 3.497 ± 0.323
1.748IleGly: 1.748 ± 1.07
0.0IleHis: 0.0 ± 0.0
1.748IleIle: 1.748 ± 1.393
3.497IleLys: 3.497 ± 2.785
1.748IleLeu: 1.748 ± 1.07
1.748IleMet: 1.748 ± 1.393
3.497IleAsn: 3.497 ± 0.323
3.497IlePro: 3.497 ± 0.323
0.0IleGln: 0.0 ± 0.0
1.748IleArg: 1.748 ± 1.393
1.748IleSer: 1.748 ± 1.393
6.993IleThr: 6.993 ± 0.646
0.0IleVal: 0.0 ± 0.0
1.748IleTrp: 1.748 ± 1.393
1.748IleTyr: 1.748 ± 1.07
0.0IleXaa: 0.0 ± 0.0
Lys
3.497LysAla: 3.497 ± 2.14
0.0LysCys: 0.0 ± 0.0
3.497LysAsp: 3.497 ± 0.323
1.748LysGlu: 1.748 ± 1.393
5.245LysPhe: 5.245 ± 3.209
1.748LysGly: 1.748 ± 1.07
1.748LysHis: 1.748 ± 1.393
1.748LysIle: 1.748 ± 1.393
0.0LysLys: 0.0 ± 0.0
1.748LysLeu: 1.748 ± 1.07
1.748LysMet: 1.748 ± 1.393
3.497LysAsn: 3.497 ± 2.785
0.0LysPro: 0.0 ± 0.0
1.748LysGln: 1.748 ± 1.393
3.497LysArg: 3.497 ± 0.323
3.497LysSer: 3.497 ± 2.785
5.245LysThr: 5.245 ± 1.716
3.497LysVal: 3.497 ± 2.785
3.497LysTrp: 3.497 ± 2.785
6.993LysTyr: 6.993 ± 3.108
0.0LysXaa: 0.0 ± 0.0
Leu
3.497LeuAla: 3.497 ± 0.323
0.0LeuCys: 0.0 ± 0.0
3.497LeuAsp: 3.497 ± 0.323
3.497LeuGlu: 3.497 ± 2.785
0.0LeuPhe: 0.0 ± 0.0
5.245LeuGly: 5.245 ± 3.209
1.748LeuHis: 1.748 ± 1.07
0.0LeuIle: 0.0 ± 0.0
6.993LeuLys: 6.993 ± 5.571
6.993LeuLeu: 6.993 ± 1.817
1.748LeuMet: 1.748 ± 1.07
3.497LeuAsn: 3.497 ± 0.323
6.993LeuPro: 6.993 ± 4.279
5.245LeuGln: 5.245 ± 0.747
3.497LeuArg: 3.497 ± 0.323
1.748LeuSer: 1.748 ± 1.07
3.497LeuThr: 3.497 ± 0.323
6.993LeuVal: 6.993 ± 3.108
1.748LeuTrp: 1.748 ± 1.393
5.245LeuTyr: 5.245 ± 0.747
0.0LeuXaa: 0.0 ± 0.0
Met
1.748MetAla: 1.748 ± 1.07
1.748MetCys: 1.748 ± 1.393
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.748MetGly: 1.748 ± 1.07
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.748MetLys: 1.748 ± 1.393
1.748MetLeu: 1.748 ± 1.07
0.0MetMet: 0.0 ± 0.0
1.748MetAsn: 1.748 ± 1.07
5.245MetPro: 5.245 ± 1.716
1.748MetGln: 1.748 ± 1.07
5.245MetArg: 5.245 ± 4.178
0.0MetSer: 0.0 ± 0.0
1.748MetThr: 1.748 ± 1.07
1.748MetVal: 1.748 ± 1.393
0.0MetTrp: 0.0 ± 0.0
3.497MetTyr: 3.497 ± 2.14
0.0MetXaa: 0.0 ± 0.0
Asn
1.748AsnAla: 1.748 ± 1.07
0.0AsnCys: 0.0 ± 0.0
1.748AsnAsp: 1.748 ± 1.07
3.497AsnGlu: 3.497 ± 0.323
6.993AsnPhe: 6.993 ± 1.817
8.741AsnGly: 8.741 ± 0.424
0.0AsnHis: 0.0 ± 0.0
1.748AsnIle: 1.748 ± 1.07
1.748AsnLys: 1.748 ± 1.393
3.497AsnLeu: 3.497 ± 2.14
5.245AsnMet: 5.245 ± 0.661
0.0AsnAsn: 0.0 ± 0.0
8.741AsnPro: 8.741 ± 2.887
1.748AsnGln: 1.748 ± 1.07
1.748AsnArg: 1.748 ± 1.07
5.245AsnSer: 5.245 ± 0.747
1.748AsnThr: 1.748 ± 1.07
1.748AsnVal: 1.748 ± 1.393
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.497ProAla: 3.497 ± 2.14
0.0ProCys: 0.0 ± 0.0
1.748ProAsp: 1.748 ± 1.07
6.993ProGlu: 6.993 ± 3.108
1.748ProPhe: 1.748 ± 1.07
5.245ProGly: 5.245 ± 3.209
1.748ProHis: 1.748 ± 1.07
1.748ProIle: 1.748 ± 1.07
5.245ProLys: 5.245 ± 1.716
3.497ProLeu: 3.497 ± 2.14
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
1.748ProPro: 1.748 ± 1.393
0.0ProGln: 0.0 ± 0.0
6.993ProArg: 6.993 ± 0.646
5.245ProSer: 5.245 ± 1.716
6.993ProThr: 6.993 ± 0.646
5.245ProVal: 5.245 ± 3.209
1.748ProTrp: 1.748 ± 1.393
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.748GlnAla: 1.748 ± 1.07
0.0GlnCys: 0.0 ± 0.0
3.497GlnAsp: 3.497 ± 0.323
0.0GlnGlu: 0.0 ± 0.0
1.748GlnPhe: 1.748 ± 1.07
1.748GlnGly: 1.748 ± 1.393
0.0GlnHis: 0.0 ± 0.0
3.497GlnIle: 3.497 ± 2.785
1.748GlnLys: 1.748 ± 1.07
3.497GlnLeu: 3.497 ± 2.14
0.0GlnMet: 0.0 ± 0.0
3.497GlnAsn: 3.497 ± 2.14
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
3.497GlnArg: 3.497 ± 0.323
5.245GlnSer: 5.245 ± 1.716
1.748GlnThr: 1.748 ± 1.07
6.993GlnVal: 6.993 ± 4.279
1.748GlnTrp: 1.748 ± 1.07
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.245ArgAla: 5.245 ± 4.178
0.0ArgCys: 0.0 ± 0.0
1.748ArgAsp: 1.748 ± 1.07
1.748ArgGlu: 1.748 ± 1.393
5.245ArgPhe: 5.245 ± 0.747
1.748ArgGly: 1.748 ± 1.393
0.0ArgHis: 0.0 ± 0.0
5.245ArgIle: 5.245 ± 0.747
3.497ArgLys: 3.497 ± 0.323
6.993ArgLeu: 6.993 ± 0.646
3.497ArgMet: 3.497 ± 0.323
3.497ArgAsn: 3.497 ± 0.323
1.748ArgPro: 1.748 ± 1.393
1.748ArgGln: 1.748 ± 1.393
5.245ArgArg: 5.245 ± 3.209
1.748ArgSer: 1.748 ± 1.07
0.0ArgThr: 0.0 ± 0.0
3.497ArgVal: 3.497 ± 2.14
1.748ArgTrp: 1.748 ± 1.07
3.497ArgTyr: 3.497 ± 2.785
0.0ArgXaa: 0.0 ± 0.0
Ser
8.741SerAla: 8.741 ± 2.038
1.748SerCys: 1.748 ± 1.393
3.497SerAsp: 3.497 ± 2.14
3.497SerGlu: 3.497 ± 2.785
1.748SerPhe: 1.748 ± 1.07
10.49SerGly: 10.49 ± 0.969
0.0SerHis: 0.0 ± 0.0
5.245SerIle: 5.245 ± 0.747
1.748SerLys: 1.748 ± 1.393
1.748SerLeu: 1.748 ± 1.393
5.245SerMet: 5.245 ± 3.209
1.748SerAsn: 1.748 ± 1.07
1.748SerPro: 1.748 ± 1.393
3.497SerGln: 3.497 ± 2.14
0.0SerArg: 0.0 ± 0.0
5.245SerSer: 5.245 ± 3.209
3.497SerThr: 3.497 ± 2.14
12.238SerVal: 12.238 ± 2.564
3.497SerTrp: 3.497 ± 2.785
3.497SerTyr: 3.497 ± 2.14
0.0SerXaa: 0.0 ± 0.0
Thr
5.245ThrAla: 5.245 ± 3.209
0.0ThrCys: 0.0 ± 0.0
1.748ThrAsp: 1.748 ± 1.07
0.0ThrGlu: 0.0 ± 0.0
0.0ThrPhe: 0.0 ± 0.0
8.741ThrGly: 8.741 ± 2.038
0.0ThrHis: 0.0 ± 0.0
1.748ThrIle: 1.748 ± 1.07
6.993ThrLys: 6.993 ± 0.646
3.497ThrLeu: 3.497 ± 2.14
1.748ThrMet: 1.748 ± 1.393
6.993ThrAsn: 6.993 ± 1.817
1.748ThrPro: 1.748 ± 1.393
1.748ThrGln: 1.748 ± 1.07
0.0ThrArg: 0.0 ± 0.0
3.497ThrSer: 3.497 ± 0.323
1.748ThrThr: 1.748 ± 1.07
5.245ThrVal: 5.245 ± 0.747
1.748ThrTrp: 1.748 ± 1.393
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.748ValAla: 1.748 ± 1.07
1.748ValCys: 1.748 ± 1.393
6.993ValAsp: 6.993 ± 4.279
3.497ValGlu: 3.497 ± 0.323
3.497ValPhe: 3.497 ± 0.323
1.748ValGly: 1.748 ± 1.07
0.0ValHis: 0.0 ± 0.0
3.497ValIle: 3.497 ± 0.323
0.0ValLys: 0.0 ± 0.0
3.497ValLeu: 3.497 ± 2.785
1.748ValMet: 1.748 ± 1.07
3.497ValAsn: 3.497 ± 2.14
6.993ValPro: 6.993 ± 0.646
1.748ValGln: 1.748 ± 1.07
6.993ValArg: 6.993 ± 1.817
12.238ValSer: 12.238 ± 2.361
3.497ValThr: 3.497 ± 2.14
1.748ValVal: 1.748 ± 1.07
3.497ValTrp: 3.497 ± 2.785
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.748TrpAla: 1.748 ± 1.393
0.0TrpCys: 0.0 ± 0.0
1.748TrpAsp: 1.748 ± 1.393
1.748TrpGlu: 1.748 ± 1.393
1.748TrpPhe: 1.748 ± 1.07
0.0TrpGly: 0.0 ± 0.0
1.748TrpHis: 1.748 ± 1.07
3.497TrpIle: 3.497 ± 2.785
0.0TrpLys: 0.0 ± 0.0
3.497TrpLeu: 3.497 ± 2.785
1.748TrpMet: 1.748 ± 1.07
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.748TrpGln: 1.748 ± 1.393
0.0TrpArg: 0.0 ± 0.0
5.245TrpSer: 5.245 ± 1.716
0.0TrpThr: 0.0 ± 0.0
1.748TrpVal: 1.748 ± 1.393
0.0TrpTrp: 0.0 ± 0.0
3.497TrpTyr: 3.497 ± 0.323
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.497TyrAla: 3.497 ± 0.323
3.497TyrCys: 3.497 ± 2.785
6.993TyrAsp: 6.993 ± 0.646
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
1.748TyrGly: 1.748 ± 1.393
0.0TyrHis: 0.0 ± 0.0
3.497TyrIle: 3.497 ± 0.323
6.993TyrLys: 6.993 ± 1.817
1.748TyrLeu: 1.748 ± 1.393
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
5.245TyrPro: 5.245 ± 0.747
3.497TyrGln: 3.497 ± 0.323
1.748TyrArg: 1.748 ± 1.07
3.497TyrSer: 3.497 ± 2.14
1.748TyrThr: 1.748 ± 1.393
3.497TyrVal: 3.497 ± 2.785
1.748TyrTrp: 1.748 ± 1.07
3.497TyrTyr: 3.497 ± 2.14
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski