Amino acid dipepetide frequency for Beihai picobirna-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.855AlaAla: 1.855 ± 0.106
0.0AlaCys: 0.0 ± 0.0
2.783AlaAsp: 2.783 ± 0.512
1.855AlaGlu: 1.855 ± 0.106
3.711AlaPhe: 3.711 ± 1.13
0.0AlaGly: 0.0 ± 0.0
0.928AlaHis: 0.928 ± 0.618
1.855AlaIle: 1.855 ± 0.106
0.928AlaLys: 0.928 ± 0.618
7.421AlaLeu: 7.421 ± 0.423
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
0.0AlaPro: 0.0 ± 0.0
0.928AlaGln: 0.928 ± 0.618
1.855AlaArg: 1.855 ± 1.236
5.566AlaSer: 5.566 ± 2.365
0.0AlaThr: 0.0 ± 0.0
4.638AlaVal: 4.638 ± 0.406
0.0AlaTrp: 0.0 ± 0.0
2.783AlaTyr: 2.783 ± 0.512
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.928CysGlu: 0.928 ± 0.618
0.0CysPhe: 0.0 ± 0.0
1.855CysGly: 1.855 ± 0.106
0.0CysHis: 0.0 ± 0.0
1.855CysIle: 1.855 ± 0.106
0.928CysLys: 0.928 ± 0.724
0.928CysLeu: 0.928 ± 0.724
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.855CysPro: 1.855 ± 1.236
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.928CysSer: 0.928 ± 0.618
0.928CysThr: 0.928 ± 0.618
3.711CysVal: 3.711 ± 2.894
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.711AspAla: 3.711 ± 0.212
0.928AspCys: 0.928 ± 0.618
5.566AspAsp: 5.566 ± 0.317
1.855AspGlu: 1.855 ± 1.236
2.783AspPhe: 2.783 ± 0.829
2.783AspGly: 2.783 ± 2.171
1.855AspHis: 1.855 ± 1.236
3.711AspIle: 3.711 ± 0.212
9.276AspLys: 9.276 ± 0.529
6.494AspLeu: 6.494 ± 0.3
0.0AspMet: 0.0 ± 0.0
2.783AspAsn: 2.783 ± 0.512
1.855AspPro: 1.855 ± 0.106
1.855AspGln: 1.855 ± 1.236
1.855AspArg: 1.855 ± 1.447
10.204AspSer: 10.204 ± 1.252
5.566AspThr: 5.566 ± 0.317
6.494AspVal: 6.494 ± 0.3
0.0AspTrp: 0.0 ± 0.0
5.566AspTyr: 5.566 ± 1.659
0.0AspXaa: 0.0 ± 0.0
Glu
0.928GluAla: 0.928 ± 0.618
0.0GluCys: 0.0 ± 0.0
7.421GluAsp: 7.421 ± 3.106
0.928GluGlu: 0.928 ± 0.724
1.855GluPhe: 1.855 ± 0.106
3.711GluGly: 3.711 ± 1.13
1.855GluHis: 1.855 ± 0.106
0.928GluIle: 0.928 ± 0.724
1.855GluLys: 1.855 ± 0.106
2.783GluLeu: 2.783 ± 0.829
0.928GluMet: 0.928 ± 0.724
3.711GluAsn: 3.711 ± 1.13
0.0GluPro: 0.0 ± 0.0
0.928GluGln: 0.928 ± 0.618
2.783GluArg: 2.783 ± 0.829
3.711GluSer: 3.711 ± 1.553
1.855GluThr: 1.855 ± 0.106
3.711GluVal: 3.711 ± 0.212
0.0GluTrp: 0.0 ± 0.0
2.783GluTyr: 2.783 ± 0.512
0.0GluXaa: 0.0 ± 0.0
Phe
0.928PheAla: 0.928 ± 0.618
0.0PheCys: 0.0 ± 0.0
0.928PheAsp: 0.928 ± 0.618
8.349PheGlu: 8.349 ± 2.488
0.928PhePhe: 0.928 ± 0.618
2.783PheGly: 2.783 ± 0.512
0.0PheHis: 0.0 ± 0.0
0.928PheIle: 0.928 ± 0.618
2.783PheLys: 2.783 ± 0.829
1.855PheLeu: 1.855 ± 0.106
0.928PheMet: 0.928 ± 0.618
4.638PheAsn: 4.638 ± 0.935
0.0PhePro: 0.0 ± 0.0
0.928PheGln: 0.928 ± 0.724
1.855PheArg: 1.855 ± 0.106
4.638PheSer: 4.638 ± 2.276
5.566PheThr: 5.566 ± 0.317
2.783PheVal: 2.783 ± 0.829
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.928GlyAla: 0.928 ± 0.618
0.0GlyCys: 0.0 ± 0.0
2.783GlyAsp: 2.783 ± 0.512
1.855GlyGlu: 1.855 ± 1.236
0.0GlyPhe: 0.0 ± 0.0
7.421GlyGly: 7.421 ± 3.601
1.855GlyHis: 1.855 ± 0.106
3.711GlyIle: 3.711 ± 2.894
5.566GlyLys: 5.566 ± 1.024
7.421GlyLeu: 7.421 ± 3.106
1.855GlyMet: 1.855 ± 1.236
4.638GlyAsn: 4.638 ± 1.748
3.711GlyPro: 3.711 ± 1.13
1.855GlyGln: 1.855 ± 1.236
2.783GlyArg: 2.783 ± 0.512
9.276GlySer: 9.276 ± 4.837
1.855GlyThr: 1.855 ± 0.106
9.276GlyVal: 9.276 ± 2.154
1.855GlyTrp: 1.855 ± 0.106
1.855GlyTyr: 1.855 ± 1.447
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.928HisCys: 0.928 ± 0.618
0.928HisAsp: 0.928 ± 0.724
0.928HisGlu: 0.928 ± 0.618
1.855HisPhe: 1.855 ± 0.106
0.928HisGly: 0.928 ± 0.724
0.928HisHis: 0.928 ± 0.724
0.928HisIle: 0.928 ± 0.618
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.928HisMet: 0.928 ± 0.618
3.711HisAsn: 3.711 ± 0.212
2.783HisPro: 2.783 ± 0.829
0.0HisGln: 0.0 ± 0.0
1.855HisArg: 1.855 ± 1.236
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.928HisTrp: 0.928 ± 0.618
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.711IleAla: 3.711 ± 0.212
2.783IleCys: 2.783 ± 0.829
8.349IleAsp: 8.349 ± 1.536
0.928IleGlu: 0.928 ± 0.724
3.711IlePhe: 3.711 ± 0.212
3.711IleGly: 3.711 ± 1.13
0.928IleHis: 0.928 ± 0.724
2.783IleIle: 2.783 ± 0.829
2.783IleLys: 2.783 ± 0.829
5.566IleLeu: 5.566 ± 1.659
0.0IleMet: 0.0 ± 0.0
4.638IleAsn: 4.638 ± 1.748
1.855IlePro: 1.855 ± 1.236
2.783IleGln: 2.783 ± 2.171
3.711IleArg: 3.711 ± 1.13
3.711IleSer: 3.711 ± 0.212
0.928IleThr: 0.928 ± 0.724
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
6.494IleTyr: 6.494 ± 0.3
0.0IleXaa: 0.0 ± 0.0
Lys
3.711LysAla: 3.711 ± 1.553
0.0LysCys: 0.0 ± 0.0
3.711LysAsp: 3.711 ± 0.212
2.783LysGlu: 2.783 ± 0.829
0.928LysPhe: 0.928 ± 0.724
3.711LysGly: 3.711 ± 1.13
2.783LysHis: 2.783 ± 0.512
7.421LysIle: 7.421 ± 0.918
3.711LysLys: 3.711 ± 1.13
12.059LysLeu: 12.059 ± 1.358
0.928LysMet: 0.928 ± 0.724
4.638LysAsn: 4.638 ± 1.748
2.783LysPro: 2.783 ± 0.512
1.855LysGln: 1.855 ± 1.447
0.928LysArg: 0.928 ± 0.618
5.566LysSer: 5.566 ± 3.0
1.855LysThr: 1.855 ± 0.106
3.711LysVal: 3.711 ± 0.212
1.855LysTrp: 1.855 ± 1.236
4.638LysTyr: 4.638 ± 2.276
0.0LysXaa: 0.0 ± 0.0
Leu
1.855LeuAla: 1.855 ± 0.106
0.0LeuCys: 0.0 ± 0.0
11.132LeuAsp: 11.132 ± 1.976
4.638LeuGlu: 4.638 ± 2.276
4.638LeuPhe: 4.638 ± 2.276
3.711LeuGly: 3.711 ± 0.212
0.928LeuHis: 0.928 ± 0.724
6.494LeuIle: 6.494 ± 1.041
7.421LeuLys: 7.421 ± 1.764
5.566LeuLeu: 5.566 ± 1.659
2.783LeuMet: 2.783 ± 0.925
8.349LeuAsn: 8.349 ± 2.488
4.638LeuPro: 4.638 ± 0.935
4.638LeuGln: 4.638 ± 0.406
3.711LeuArg: 3.711 ± 1.553
4.638LeuSer: 4.638 ± 2.276
6.494LeuThr: 6.494 ± 2.983
3.711LeuVal: 3.711 ± 1.553
0.928LeuTrp: 0.928 ± 0.618
2.783LeuTyr: 2.783 ± 0.829
0.0LeuXaa: 0.0 ± 0.0
Met
0.928MetAla: 0.928 ± 0.724
0.928MetCys: 0.928 ± 0.724
0.928MetAsp: 0.928 ± 0.618
0.928MetGlu: 0.928 ± 0.724
1.855MetPhe: 1.855 ± 0.106
1.855MetGly: 1.855 ± 1.236
0.928MetHis: 0.928 ± 0.618
0.0MetIle: 0.0 ± 0.0
0.928MetLys: 0.928 ± 0.724
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
2.783MetAsn: 2.783 ± 0.512
0.928MetPro: 0.928 ± 0.618
0.928MetGln: 0.928 ± 0.724
0.0MetArg: 0.0 ± 0.0
0.928MetSer: 0.928 ± 0.618
0.0MetThr: 0.0 ± 0.0
0.928MetVal: 0.928 ± 0.724
0.0MetTrp: 0.0 ± 0.0
2.783MetTyr: 2.783 ± 1.853
0.0MetXaa: 0.0 ± 0.0
Asn
1.855AsnAla: 1.855 ± 1.236
1.855AsnCys: 1.855 ± 0.106
3.711AsnAsp: 3.711 ± 1.553
3.711AsnGlu: 3.711 ± 0.212
2.783AsnPhe: 2.783 ± 0.512
3.711AsnGly: 3.711 ± 2.471
0.928AsnHis: 0.928 ± 0.618
4.638AsnIle: 4.638 ± 0.935
4.638AsnLys: 4.638 ± 0.406
6.494AsnLeu: 6.494 ± 2.382
1.855AsnMet: 1.855 ± 0.106
3.711AsnAsn: 3.711 ± 0.212
1.855AsnPro: 1.855 ± 1.236
0.928AsnGln: 0.928 ± 0.724
9.276AsnArg: 9.276 ± 0.813
3.711AsnSer: 3.711 ± 0.212
3.711AsnThr: 3.711 ± 1.13
4.638AsnVal: 4.638 ± 1.748
0.928AsnTrp: 0.928 ± 0.724
4.638AsnTyr: 4.638 ± 1.748
0.0AsnXaa: 0.0 ± 0.0
Pro
1.855ProAla: 1.855 ± 1.236
1.855ProCys: 1.855 ± 0.106
1.855ProAsp: 1.855 ± 1.447
3.711ProGlu: 3.711 ± 0.212
2.783ProPhe: 2.783 ± 1.853
2.783ProGly: 2.783 ± 1.853
0.0ProHis: 0.0 ± 0.0
0.928ProIle: 0.928 ± 0.618
0.0ProLys: 0.0 ± 0.0
8.349ProLeu: 8.349 ± 2.488
2.783ProMet: 2.783 ± 0.512
0.0ProAsn: 0.0 ± 0.0
3.711ProPro: 3.711 ± 1.13
0.928ProGln: 0.928 ± 0.618
3.711ProArg: 3.711 ± 0.212
3.711ProSer: 3.711 ± 1.553
1.855ProThr: 1.855 ± 0.106
0.0ProVal: 0.0 ± 0.0
1.855ProTrp: 1.855 ± 0.106
3.711ProTyr: 3.711 ± 1.13
0.0ProXaa: 0.0 ± 0.0
Gln
2.783GlnAla: 2.783 ± 1.853
0.0GlnCys: 0.0 ± 0.0
2.783GlnAsp: 2.783 ± 0.829
2.783GlnGlu: 2.783 ± 0.829
1.855GlnPhe: 1.855 ± 0.106
2.783GlnGly: 2.783 ± 2.171
0.0GlnHis: 0.0 ± 0.0
2.783GlnIle: 2.783 ± 0.512
0.928GlnLys: 0.928 ± 0.724
0.928GlnLeu: 0.928 ± 0.618
0.0GlnMet: 0.0 ± 0.0
4.638GlnAsn: 4.638 ± 0.406
0.928GlnPro: 0.928 ± 0.724
1.855GlnGln: 1.855 ± 1.236
1.855GlnArg: 1.855 ± 0.106
0.928GlnSer: 0.928 ± 0.618
0.928GlnThr: 0.928 ± 0.618
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.855GlnTyr: 1.855 ± 0.106
0.0GlnXaa: 0.0 ± 0.0
Arg
2.783ArgAla: 2.783 ± 0.512
0.0ArgCys: 0.0 ± 0.0
3.711ArgAsp: 3.711 ± 1.553
1.855ArgGlu: 1.855 ± 0.106
2.783ArgPhe: 2.783 ± 2.171
3.711ArgGly: 3.711 ± 2.471
0.0ArgHis: 0.0 ± 0.0
1.855ArgIle: 1.855 ± 1.236
6.494ArgLys: 6.494 ± 0.3
5.566ArgLeu: 5.566 ± 1.024
0.0ArgMet: 0.0 ± 0.0
6.494ArgAsn: 6.494 ± 2.983
3.711ArgPro: 3.711 ± 1.553
1.855ArgGln: 1.855 ± 1.236
3.711ArgArg: 3.711 ± 1.553
4.638ArgSer: 4.638 ± 3.618
3.711ArgThr: 3.711 ± 0.212
0.0ArgVal: 0.0 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
3.711ArgTyr: 3.711 ± 1.13
0.0ArgXaa: 0.0 ± 0.0
Ser
2.783SerAla: 2.783 ± 0.512
1.855SerCys: 1.855 ± 0.106
7.421SerAsp: 7.421 ± 3.601
1.855SerGlu: 1.855 ± 1.236
2.783SerPhe: 2.783 ± 2.171
11.132SerGly: 11.132 ± 1.976
0.0SerHis: 0.0 ± 0.0
8.349SerIle: 8.349 ± 2.488
6.494SerLys: 6.494 ± 1.041
6.494SerLeu: 6.494 ± 2.382
0.928SerMet: 0.928 ± 0.724
3.711SerAsn: 3.711 ± 0.212
5.566SerPro: 5.566 ± 0.317
0.928SerGln: 0.928 ± 0.618
1.855SerArg: 1.855 ± 0.106
7.421SerSer: 7.421 ± 0.918
4.638SerThr: 4.638 ± 1.748
2.783SerVal: 2.783 ± 0.829
0.928SerTrp: 0.928 ± 0.618
5.566SerTyr: 5.566 ± 0.317
0.0SerXaa: 0.0 ± 0.0
Thr
2.783ThrAla: 2.783 ± 0.512
0.0ThrCys: 0.0 ± 0.0
4.638ThrAsp: 4.638 ± 3.089
0.0ThrGlu: 0.0 ± 0.0
0.928ThrPhe: 0.928 ± 0.724
3.711ThrGly: 3.711 ± 1.13
0.0ThrHis: 0.0 ± 0.0
2.783ThrIle: 2.783 ± 0.512
1.855ThrLys: 1.855 ± 0.106
0.928ThrLeu: 0.928 ± 0.618
1.855ThrMet: 1.855 ± 0.382
4.638ThrAsn: 4.638 ± 0.935
1.855ThrPro: 1.855 ± 0.106
2.783ThrGln: 2.783 ± 0.512
4.638ThrArg: 4.638 ± 0.406
4.638ThrSer: 4.638 ± 3.089
1.855ThrThr: 1.855 ± 1.236
2.783ThrVal: 2.783 ± 2.171
0.928ThrTrp: 0.928 ± 0.618
4.638ThrTyr: 4.638 ± 1.748
0.0ThrXaa: 0.0 ± 0.0
Val
2.783ValAla: 2.783 ± 1.853
0.0ValCys: 0.0 ± 0.0
2.783ValAsp: 2.783 ± 2.171
0.0ValGlu: 0.0 ± 0.0
1.855ValPhe: 1.855 ± 1.236
0.928ValGly: 0.928 ± 0.618
0.928ValHis: 0.928 ± 0.618
3.711ValIle: 3.711 ± 2.471
7.421ValLys: 7.421 ± 3.106
3.711ValLeu: 3.711 ± 2.894
0.928ValMet: 0.928 ± 0.724
3.711ValAsn: 3.711 ± 1.553
5.566ValPro: 5.566 ± 1.024
3.711ValGln: 3.711 ± 1.553
0.928ValArg: 0.928 ± 0.618
4.638ValSer: 4.638 ± 0.406
1.855ValThr: 1.855 ± 0.106
0.0ValVal: 0.0 ± 0.0
1.855ValTrp: 1.855 ± 0.106
4.638ValTyr: 4.638 ± 0.935
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.928TrpCys: 0.928 ± 0.618
0.928TrpAsp: 0.928 ± 0.724
0.928TrpGlu: 0.928 ± 0.618
0.0TrpPhe: 0.0 ± 0.0
2.783TrpGly: 2.783 ± 0.512
0.928TrpHis: 0.928 ± 0.618
0.928TrpIle: 0.928 ± 0.618
1.855TrpLys: 1.855 ± 1.236
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.855TrpArg: 1.855 ± 0.106
0.928TrpSer: 0.928 ± 0.618
0.0TrpThr: 0.0 ± 0.0
1.855TrpVal: 1.855 ± 0.106
0.928TrpTrp: 0.928 ± 0.618
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.928TyrAla: 0.928 ± 0.618
1.855TyrCys: 1.855 ± 1.447
2.783TyrAsp: 2.783 ± 0.512
1.855TyrGlu: 1.855 ± 1.447
2.783TyrPhe: 2.783 ± 0.829
6.494TyrGly: 6.494 ± 1.642
1.855TyrHis: 1.855 ± 1.447
2.783TyrIle: 2.783 ± 0.829
3.711TyrLys: 3.711 ± 1.13
6.494TyrLeu: 6.494 ± 0.3
0.928TyrMet: 0.928 ± 0.618
2.783TyrAsn: 2.783 ± 0.512
2.783TyrPro: 2.783 ± 0.829
0.928TyrGln: 0.928 ± 0.724
7.421TyrArg: 7.421 ± 0.423
3.711TyrSer: 3.711 ± 1.553
5.566TyrThr: 5.566 ± 3.707
0.928TyrVal: 0.928 ± 0.618
1.855TyrTrp: 1.855 ± 1.236
5.566TyrTyr: 5.566 ± 1.024
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1079 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski