Amino acid dipepetide frequency for Eragrostis curvula (weeping love grass)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.334AlaAla: 13.334 ± 0.056	1.658AlaCys: 1.658 ± 0.011	4.31AlaAsp: 4.31 ± 0.018	4.99AlaGlu: 4.99 ± 0.019	3.032AlaPhe: 3.032 ± 0.015	6.599AlaGly: 6.599 ± 0.026	1.78AlaHis: 1.78 ± 0.01	3.532AlaIle: 3.532 ± 0.012	3.743AlaLys: 3.743 ± 0.015	7.896AlaLeu: 7.896 ± 0.026	2.256AlaMet: 2.256 ± 0.011	2.524AlaAsn: 2.524 ± 0.012	5.083AlaPro: 5.083 ± 0.024	2.473AlaGln: 2.473 ± 0.011	5.545AlaArg: 5.545 ± 0.021	7.512AlaSer: 7.512 ± 0.024	4.867AlaThr: 4.867 ± 0.016	6.789AlaVal: 6.789 ± 0.025	1.055AlaTrp: 1.055 ± 0.007	1.924AlaTyr: 1.924 ± 0.011	0.0AlaXaa: 0.0 ± 0.0
Cys	1.466CysAla: 1.466 ± 0.008	0.647CysCys: 0.647 ± 0.007	0.978CysAsp: 0.978 ± 0.008	0.855CysGlu: 0.855 ± 0.007	0.911CysPhe: 0.911 ± 0.007	1.533CysGly: 1.533 ± 0.01	0.548CysHis: 0.548 ± 0.006	0.95CysIle: 0.95 ± 0.008	0.984CysLys: 0.984 ± 0.008	1.924CysLeu: 1.924 ± 0.009	0.459CysMet: 0.459 ± 0.005	0.776CysAsn: 0.776 ± 0.007	1.148CysPro: 1.148 ± 0.009	0.594CysGln: 0.594 ± 0.006	1.435CysArg: 1.435 ± 0.01	1.953CysSer: 1.953 ± 0.01	0.997CysThr: 0.997 ± 0.007	1.236CysVal: 1.236 ± 0.008	0.289CysTrp: 0.289 ± 0.004	0.566CysTyr: 0.566 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.934AspAla: 4.934 ± 0.019	0.994AspCys: 0.994 ± 0.008	4.314AspAsp: 4.314 ± 0.021	3.974AspGlu: 3.974 ± 0.017	2.001AspPhe: 2.001 ± 0.011	4.616AspGly: 4.616 ± 0.018	1.284AspHis: 1.284 ± 0.009	2.667AspIle: 2.667 ± 0.013	2.38AspLys: 2.38 ± 0.011	5.01AspLeu: 5.01 ± 0.018	1.437AspMet: 1.437 ± 0.01	1.802AspAsn: 1.802 ± 0.009	2.801AspPro: 2.801 ± 0.014	1.608AspGln: 1.608 ± 0.01	2.734AspArg: 2.734 ± 0.013	3.626AspSer: 3.626 ± 0.015	2.325AspThr: 2.325 ± 0.011	3.936AspVal: 3.936 ± 0.015	0.733AspTrp: 0.733 ± 0.006	1.415AspTyr: 1.415 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	5.393GluAla: 5.393 ± 0.02	0.895GluCys: 0.895 ± 0.007	3.783GluAsp: 3.783 ± 0.017	5.605GluGlu: 5.605 ± 0.029	2.013GluPhe: 2.013 ± 0.01	3.62GluGly: 3.62 ± 0.014	1.415GluHis: 1.415 ± 0.008	2.842GluIle: 2.842 ± 0.012	3.622GluLys: 3.622 ± 0.017	5.897GluLeu: 5.897 ± 0.02	1.671GluMet: 1.671 ± 0.009	2.129GluAsn: 2.129 ± 0.012	2.371GluPro: 2.371 ± 0.013	2.184GluGln: 2.184 ± 0.012	3.527GluArg: 3.527 ± 0.017	3.67GluSer: 3.67 ± 0.016	2.555GluThr: 2.555 ± 0.013	4.018GluVal: 4.018 ± 0.014	0.775GluTrp: 0.775 ± 0.007	1.454GluTyr: 1.454 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	2.881PheAla: 2.881 ± 0.013	0.824PheCys: 0.824 ± 0.006	2.144PheAsp: 2.144 ± 0.011	1.836PheGlu: 1.836 ± 0.009	1.732PhePhe: 1.732 ± 0.011	2.806PheGly: 2.806 ± 0.015	1.044PheHis: 1.044 ± 0.007	1.63PheIle: 1.63 ± 0.01	1.538PheLys: 1.538 ± 0.01	3.946PheLeu: 3.946 ± 0.015	0.872PheMet: 0.872 ± 0.007	1.299PheAsn: 1.299 ± 0.008	2.009PhePro: 2.009 ± 0.011	1.257PheGln: 1.257 ± 0.009	2.131PheArg: 2.131 ± 0.011	3.259PheSer: 3.259 ± 0.014	1.769PheThr: 1.769 ± 0.01	2.725PheVal: 2.725 ± 0.014	0.519PheTrp: 0.519 ± 0.005	1.092PheTyr: 1.092 ± 0.008	0.0PheXaa: 0.0 ± 0.0
Gly	6.032GlyAla: 6.032 ± 0.02	1.55GlyCys: 1.55 ± 0.01	4.013GlyAsp: 4.013 ± 0.015	3.826GlyGlu: 3.826 ± 0.015	2.849GlyPhe: 2.849 ± 0.013	7.07GlyGly: 7.07 ± 0.037	1.795GlyHis: 1.795 ± 0.01	3.032GlyIle: 3.032 ± 0.014	3.507GlyLys: 3.507 ± 0.015	5.861GlyLeu: 5.861 ± 0.018	1.599GlyMet: 1.599 ± 0.01	2.694GlyAsn: 2.694 ± 0.011	2.882GlyPro: 2.882 ± 0.013	2.112GlyGln: 2.112 ± 0.012	4.779GlyArg: 4.779 ± 0.02	5.98GlySer: 5.98 ± 0.019	3.492GlyThr: 3.492 ± 0.013	4.626GlyVal: 4.626 ± 0.017	0.999GlyTrp: 0.999 ± 0.008	1.985GlyTyr: 1.985 ± 0.013	0.0GlyXaa: 0.0 ± 0.0
His	1.97HisAla: 1.97 ± 0.012	0.592HisCys: 0.592 ± 0.005	1.315HisAsp: 1.315 ± 0.009	1.277HisGlu: 1.277 ± 0.009	0.928HisPhe: 0.928 ± 0.007	2.14HisGly: 2.14 ± 0.01	1.01HisHis: 1.01 ± 0.009	1.099HisIle: 1.099 ± 0.008	0.996HisLys: 0.996 ± 0.008	2.613HisLeu: 2.613 ± 0.012	0.564HisMet: 0.564 ± 0.005	0.823HisAsn: 0.823 ± 0.006	1.551HisPro: 1.551 ± 0.01	0.942HisGln: 0.942 ± 0.007	1.784HisArg: 1.784 ± 0.01	1.695HisSer: 1.695 ± 0.01	0.994HisThr: 0.994 ± 0.008	1.715HisVal: 1.715 ± 0.009	0.332HisTrp: 0.332 ± 0.004	0.655HisTyr: 0.655 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	3.421IleAla: 3.421 ± 0.014	0.997IleCys: 0.997 ± 0.007	2.492IleAsp: 2.492 ± 0.012	2.433IleGlu: 2.433 ± 0.011	1.748IlePhe: 1.748 ± 0.011	2.934IleGly: 2.934 ± 0.014	1.116IleHis: 1.116 ± 0.008	2.176IleIle: 2.176 ± 0.014	2.216IleLys: 2.216 ± 0.012	4.213IleLeu: 4.213 ± 0.017	1.022IleMet: 1.022 ± 0.007	1.652IleAsn: 1.652 ± 0.009	2.419IlePro: 2.419 ± 0.018	1.546IleGln: 1.546 ± 0.009	2.483IleArg: 2.483 ± 0.012	3.798IleSer: 3.798 ± 0.014	2.225IleThr: 2.225 ± 0.011	3.022IleVal: 3.022 ± 0.011	0.598IleTrp: 0.598 ± 0.006	1.201IleTyr: 1.201 ± 0.008	0.0IleXaa: 0.0 ± 0.0
Lys	3.824LysAla: 3.824 ± 0.015	0.858LysCys: 0.858 ± 0.006	2.738LysAsp: 2.738 ± 0.012	3.587LysGlu: 3.587 ± 0.019	1.627LysPhe: 1.627 ± 0.011	2.969LysGly: 2.969 ± 0.013	1.18LysHis: 1.18 ± 0.008	2.458LysIle: 2.458 ± 0.013	3.642LysLys: 3.642 ± 0.018	4.905LysLeu: 4.905 ± 0.018	1.286LysMet: 1.286 ± 0.008	1.89LysAsn: 1.89 ± 0.011	2.288LysPro: 2.288 ± 0.013	1.863LysGln: 1.863 ± 0.011	3.195LysArg: 3.195 ± 0.015	3.339LysSer: 3.339 ± 0.015	2.218LysThr: 2.218 ± 0.01	3.242LysVal: 3.242 ± 0.014	0.614LysTrp: 0.614 ± 0.005	1.301LysTyr: 1.301 ± 0.009	0.0LysXaa: 0.0 ± 0.0
Leu	8.187LeuAla: 8.187 ± 0.026	1.975LeuCys: 1.975 ± 0.01	5.139LeuAsp: 5.139 ± 0.019	5.636LeuGlu: 5.636 ± 0.024	3.437LeuPhe: 3.437 ± 0.016	5.911LeuGly: 5.911 ± 0.02	2.778LeuHis: 2.778 ± 0.013	3.694LeuIle: 3.694 ± 0.017	4.787LeuLys: 4.787 ± 0.02	10.624LeuLeu: 10.624 ± 0.035	2.047LeuMet: 2.047 ± 0.01	3.009LeuAsn: 3.009 ± 0.015	6.113LeuPro: 6.113 ± 0.022	4.024LeuGln: 4.024 ± 0.016	6.64LeuArg: 6.64 ± 0.02	7.788LeuSer: 7.788 ± 0.026	4.307LeuThr: 4.307 ± 0.014	6.686LeuVal: 6.686 ± 0.021	1.212LeuTrp: 1.212 ± 0.008	2.238LeuTyr: 2.238 ± 0.012	0.0LeuXaa: 0.0 ± 0.0
Met	2.672MetAla: 2.672 ± 0.012	0.376MetCys: 0.376 ± 0.004	1.507MetAsp: 1.507 ± 0.009	1.849MetGlu: 1.849 ± 0.01	0.795MetPhe: 0.795 ± 0.006	1.478MetGly: 1.478 ± 0.009	0.577MetHis: 0.577 ± 0.005	0.957MetIle: 0.957 ± 0.008	1.306MetLys: 1.306 ± 0.008	2.259MetLeu: 2.259 ± 0.012	0.687MetMet: 0.687 ± 0.007	0.813MetAsn: 0.813 ± 0.007	1.274MetPro: 1.274 ± 0.008	0.916MetGln: 0.916 ± 0.008	1.358MetArg: 1.358 ± 0.009	1.753MetSer: 1.753 ± 0.01	1.084MetThr: 1.084 ± 0.007	1.679MetVal: 1.679 ± 0.01	0.28MetTrp: 0.28 ± 0.004	0.59MetTyr: 0.59 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.603AsnAla: 2.603 ± 0.012	0.736AsnCys: 0.736 ± 0.008	1.708AsnAsp: 1.708 ± 0.009	1.838AsnGlu: 1.838 ± 0.011	1.382AsnPhe: 1.382 ± 0.011	2.724AsnGly: 2.724 ± 0.013	0.858AsnHis: 0.858 ± 0.006	1.899AsnIle: 1.899 ± 0.01	1.822AsnLys: 1.822 ± 0.011	3.68AsnLeu: 3.68 ± 0.019	0.961AsnMet: 0.961 ± 0.007	1.639AsnAsn: 1.639 ± 0.011	1.882AsnPro: 1.882 ± 0.01	1.208AsnGln: 1.208 ± 0.008	1.8AsnArg: 1.8 ± 0.01	2.732AsnSer: 2.732 ± 0.013	1.631AsnThr: 1.631 ± 0.01	2.297AsnVal: 2.297 ± 0.011	0.46AsnTrp: 0.46 ± 0.005	0.968AsnTyr: 0.968 ± 0.007	0.0AsnXaa: 0.0 ± 0.0
Pro	5.647ProAla: 5.647 ± 0.025	1.079ProCys: 1.079 ± 0.009	2.865ProAsp: 2.865 ± 0.012	3.288ProGlu: 3.288 ± 0.015	1.94ProPhe: 1.94 ± 0.011	3.475ProGly: 3.475 ± 0.016	1.299ProHis: 1.299 ± 0.009	1.904ProIle: 1.904 ± 0.011	2.258ProLys: 2.258 ± 0.012	4.686ProLeu: 4.686 ± 0.018	1.111ProMet: 1.111 ± 0.007	1.842ProAsn: 1.842 ± 0.011	5.767ProPro: 5.767 ± 0.036	1.836ProGln: 1.836 ± 0.01	3.666ProArg: 3.666 ± 0.015	5.609ProSer: 5.609 ± 0.023	2.837ProThr: 2.837 ± 0.017	3.628ProVal: 3.628 ± 0.013	0.736ProTrp: 0.736 ± 0.007	1.311ProTyr: 1.311 ± 0.009	0.0ProXaa: 0.0 ± 0.0
Gln	2.683GlnAla: 2.683 ± 0.013	0.634GlnCys: 0.634 ± 0.006	1.629GlnAsp: 1.629 ± 0.009	2.273GlnGlu: 2.273 ± 0.013	1.162GlnPhe: 1.162 ± 0.008	2.16GlnGly: 2.16 ± 0.011	0.996GlnHis: 0.996 ± 0.008	1.547GlnIle: 1.547 ± 0.009	1.791GlnLys: 1.791 ± 0.012	3.489GlnLeu: 3.489 ± 0.016	0.889GlnMet: 0.889 ± 0.007	1.274GlnAsn: 1.274 ± 0.008	1.939GlnPro: 1.939 ± 0.013	2.046GlnGln: 2.046 ± 0.021	2.264GlnArg: 2.264 ± 0.011	2.357GlnSer: 2.357 ± 0.013	1.449GlnThr: 1.449 ± 0.009	2.231GlnVal: 2.231 ± 0.011	0.474GlnTrp: 0.474 ± 0.005	0.864GlnTyr: 0.864 ± 0.007	0.0GlnXaa: 0.0 ± 0.0
Arg	5.259ArgAla: 5.259 ± 0.021	1.418ArgCys: 1.418 ± 0.01	3.13ArgAsp: 3.13 ± 0.014	3.424ArgGlu: 3.424 ± 0.014	2.34ArgPhe: 2.34 ± 0.01	4.204ArgGly: 4.204 ± 0.019	1.788ArgHis: 1.788 ± 0.011	2.694ArgIle: 2.694 ± 0.011	3.346ArgLys: 3.346 ± 0.014	6.224ArgLeu: 6.224 ± 0.018	1.484ArgMet: 1.484 ± 0.008	2.16ArgAsn: 2.16 ± 0.011	3.526ArgPro: 3.526 ± 0.016	2.133ArgGln: 2.133 ± 0.012	6.663ArgArg: 6.663 ± 0.027	5.056ArgSer: 5.056 ± 0.019	2.811ArgThr: 2.811 ± 0.01	4.005ArgVal: 4.005 ± 0.016	1.037ArgTrp: 1.037 ± 0.008	1.586ArgTyr: 1.586 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	6.573SerAla: 6.573 ± 0.02	1.805SerCys: 1.805 ± 0.011	4.065SerAsp: 4.065 ± 0.014	3.994SerGlu: 3.994 ± 0.016	3.37SerPhe: 3.37 ± 0.013	5.855SerGly: 5.855 ± 0.018	1.781SerHis: 1.781 ± 0.008	3.537SerIle: 3.537 ± 0.014	3.706SerLys: 3.706 ± 0.014	7.864SerLeu: 7.864 ± 0.024	1.966SerMet: 1.966 ± 0.009	2.946SerAsn: 2.946 ± 0.014	5.034SerPro: 5.034 ± 0.023	2.438SerGln: 2.438 ± 0.011	4.908SerArg: 4.908 ± 0.017	9.989SerSer: 9.989 ± 0.036	4.472SerThr: 4.472 ± 0.016	5.019SerVal: 5.019 ± 0.019	1.178SerTrp: 1.178 ± 0.008	2.045SerTyr: 2.045 ± 0.011	0.0SerXaa: 0.0 ± 0.0
Thr	4.448ThrAla: 4.448 ± 0.017	0.995ThrCys: 0.995 ± 0.007	2.343ThrAsp: 2.343 ± 0.011	2.593ThrGlu: 2.593 ± 0.012	1.828ThrPhe: 1.828 ± 0.01	3.538ThrGly: 3.538 ± 0.015	1.003ThrHis: 1.003 ± 0.007	2.293ThrIle: 2.293 ± 0.011	2.236ThrLys: 2.236 ± 0.011	4.326ThrLeu: 4.326 ± 0.015	1.255ThrMet: 1.255 ± 0.007	1.715ThrAsn: 1.715 ± 0.009	2.947ThrPro: 2.947 ± 0.014	1.365ThrGln: 1.365 ± 0.009	2.754ThrArg: 2.754 ± 0.013	4.326ThrSer: 4.326 ± 0.016	3.096ThrThr: 3.096 ± 0.012	3.546ThrVal: 3.546 ± 0.014	0.654ThrTrp: 0.654 ± 0.006	1.25ThrTyr: 1.25 ± 0.008	0.0ThrXaa: 0.0 ± 0.0
Val	6.723ValAla: 6.723 ± 0.025	1.282ValCys: 1.282 ± 0.008	3.925ValAsp: 3.925 ± 0.012	4.097ValGlu: 4.097 ± 0.015	2.584ValPhe: 2.584 ± 0.013	4.34ValGly: 4.34 ± 0.017	1.735ValHis: 1.735 ± 0.008	2.936ValIle: 2.936 ± 0.013	3.166ValLys: 3.166 ± 0.012	6.93ValLeu: 6.93 ± 0.022	1.573ValMet: 1.573 ± 0.009	2.143ValAsn: 2.143 ± 0.011	3.939ValPro: 3.939 ± 0.013	2.337ValGln: 2.337 ± 0.01	3.993ValArg: 3.993 ± 0.014	5.121ValSer: 5.121 ± 0.016	3.446ValThr: 3.446 ± 0.013	5.645ValVal: 5.645 ± 0.022	0.849ValTrp: 0.849 ± 0.007	1.807ValTyr: 1.807 ± 0.009	0.0ValXaa: 0.0 ± 0.0
Trp	0.969TrpAla: 0.969 ± 0.008	0.313TrpCys: 0.313 ± 0.004	0.705TrpAsp: 0.705 ± 0.007	0.742TrpGlu: 0.742 ± 0.007	0.502TrpPhe: 0.502 ± 0.005	0.745TrpGly: 0.745 ± 0.007	0.336TrpHis: 0.336 ± 0.004	0.624TrpIle: 0.624 ± 0.006	0.753TrpLys: 0.753 ± 0.006	1.311TrpLeu: 1.311 ± 0.008	0.369TrpMet: 0.369 ± 0.004	0.581TrpAsn: 0.581 ± 0.006	0.638TrpPro: 0.638 ± 0.005	0.449TrpGln: 0.449 ± 0.005	1.168TrpArg: 1.168 ± 0.007	1.066TrpSer: 1.066 ± 0.009	0.718TrpThr: 0.718 ± 0.006	0.85TrpVal: 0.85 ± 0.007	0.272TrpTrp: 0.272 ± 0.004	0.339TrpTyr: 0.339 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.883TyrAla: 1.883 ± 0.011	0.621TyrCys: 0.621 ± 0.005	1.488TyrAsp: 1.488 ± 0.009	1.32TyrGlu: 1.32 ± 0.009	1.133TyrPhe: 1.133 ± 0.007	1.966TyrGly: 1.966 ± 0.012	0.671TyrHis: 0.671 ± 0.006	1.239TyrIle: 1.239 ± 0.008	1.226TyrLys: 1.226 ± 0.008	2.573TyrLeu: 2.573 ± 0.011	0.701TyrMet: 0.701 ± 0.006	1.117TyrAsn: 1.117 ± 0.008	1.177TyrPro: 1.177 ± 0.009	0.819TyrGln: 0.819 ± 0.008	1.46TyrArg: 1.46 ± 0.01	1.917TyrSer: 1.917 ± 0.009	1.217TyrThr: 1.217 ± 0.008	1.675TyrVal: 1.675 ± 0.01	0.386TyrTrp: 0.386 ± 0.004	0.929TyrTyr: 0.929 ± 0.007	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.007XaaXaa: 0.007 ± 0.003

Statistics based on 53658 proteins (20519742 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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