Amino acid dipepetide frequency for Marine snail associated circular virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.107AlaAla: 6.107 ± 2.381
1.527AlaCys: 1.527 ± 1.147
10.687AlaAsp: 10.687 ± 3.003
4.58AlaGlu: 4.58 ± 1.234
1.527AlaPhe: 1.527 ± 1.059
3.053AlaGly: 3.053 ± 2.118
3.053AlaHis: 3.053 ± 2.294
4.58AlaIle: 4.58 ± 0.972
3.053AlaLys: 3.053 ± 0.088
6.107AlaLeu: 6.107 ± 0.175
0.0AlaMet: 0.0 ± 0.0
3.053AlaAsn: 3.053 ± 0.088
6.107AlaPro: 6.107 ± 4.237
0.0AlaGln: 0.0 ± 0.0
1.527AlaArg: 1.527 ± 1.059
0.0AlaSer: 0.0 ± 0.0
1.527AlaThr: 1.527 ± 1.059
3.053AlaVal: 3.053 ± 2.118
0.0AlaTrp: 0.0 ± 0.0
1.527AlaTyr: 1.527 ± 1.147
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.527CysGlu: 1.527 ± 1.147
1.527CysPhe: 1.527 ± 1.147
0.0CysGly: 0.0 ± 0.0
1.527CysHis: 1.527 ± 1.147
0.0CysIle: 0.0 ± 0.0
1.527CysLys: 1.527 ± 1.147
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.527CysAsn: 1.527 ± 1.147
0.0CysPro: 0.0 ± 0.0
1.527CysGln: 1.527 ± 1.059
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.527AspAla: 1.527 ± 1.059
0.0AspCys: 0.0 ± 0.0
4.58AspAsp: 4.58 ± 3.44
3.053AspGlu: 3.053 ± 2.294
4.58AspPhe: 4.58 ± 1.234
4.58AspGly: 4.58 ± 0.972
3.053AspHis: 3.053 ± 2.294
3.053AspIle: 3.053 ± 0.088
3.053AspLys: 3.053 ± 2.118
1.527AspLeu: 1.527 ± 1.147
3.053AspMet: 3.053 ± 2.118
7.634AspAsn: 7.634 ± 1.322
3.053AspPro: 3.053 ± 2.294
0.0AspGln: 0.0 ± 0.0
4.58AspArg: 4.58 ± 1.234
1.527AspSer: 1.527 ± 1.147
3.053AspThr: 3.053 ± 2.118
1.527AspVal: 1.527 ± 1.147
0.0AspTrp: 0.0 ± 0.0
3.053AspTyr: 3.053 ± 2.294
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
4.58GluGlu: 4.58 ± 1.234
3.053GluPhe: 3.053 ± 0.088
4.58GluGly: 4.58 ± 3.178
0.0GluHis: 0.0 ± 0.0
1.527GluIle: 1.527 ± 1.147
3.053GluLys: 3.053 ± 2.118
4.58GluLeu: 4.58 ± 0.972
1.527GluMet: 1.527 ± 1.059
4.58GluAsn: 4.58 ± 1.234
4.58GluPro: 4.58 ± 1.234
4.58GluGln: 4.58 ± 1.234
1.527GluArg: 1.527 ± 1.147
3.053GluSer: 3.053 ± 2.294
3.053GluThr: 3.053 ± 2.118
4.58GluVal: 4.58 ± 3.44
1.527GluTrp: 1.527 ± 1.147
4.58GluTyr: 4.58 ± 1.234
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
4.58PheAsp: 4.58 ± 1.234
9.16PheGlu: 9.16 ± 2.469
3.053PhePhe: 3.053 ± 2.118
4.58PheGly: 4.58 ± 3.44
1.527PheHis: 1.527 ± 1.059
3.053PheIle: 3.053 ± 2.118
3.053PheLys: 3.053 ± 2.118
1.527PheLeu: 1.527 ± 1.147
0.0PheMet: 0.0 ± 0.0
1.527PheAsn: 1.527 ± 1.059
3.053PhePro: 3.053 ± 2.294
0.0PheGln: 0.0 ± 0.0
3.053PheArg: 3.053 ± 2.294
3.053PheSer: 3.053 ± 2.294
4.58PheThr: 4.58 ± 0.972
6.107PheVal: 6.107 ± 2.031
0.0PheTrp: 0.0 ± 0.0
1.527PheTyr: 1.527 ± 1.059
0.0PheXaa: 0.0 ± 0.0
Gly
1.527GlyAla: 1.527 ± 1.147
0.0GlyCys: 0.0 ± 0.0
3.053GlyAsp: 3.053 ± 2.294
7.634GlyGlu: 7.634 ± 0.884
3.053GlyPhe: 3.053 ± 0.088
4.58GlyGly: 4.58 ± 0.972
0.0GlyHis: 0.0 ± 0.0
1.527GlyIle: 1.527 ± 1.059
6.107GlyLys: 6.107 ± 2.381
3.053GlyLeu: 3.053 ± 2.118
1.527GlyMet: 1.527 ± 1.79
4.58GlyAsn: 4.58 ± 0.972
0.0GlyPro: 0.0 ± 0.0
3.053GlyGln: 3.053 ± 0.088
7.634GlyArg: 7.634 ± 1.322
3.053GlySer: 3.053 ± 2.118
4.58GlyThr: 4.58 ± 0.972
1.527GlyVal: 1.527 ± 1.059
0.0GlyTrp: 0.0 ± 0.0
4.58GlyTyr: 4.58 ± 0.972
0.0GlyXaa: 0.0 ± 0.0
His
3.053HisAla: 3.053 ± 2.294
0.0HisCys: 0.0 ± 0.0
1.527HisAsp: 1.527 ± 1.147
3.053HisGlu: 3.053 ± 0.088
1.527HisPhe: 1.527 ± 1.059
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.527HisIle: 1.527 ± 1.147
0.0HisLys: 0.0 ± 0.0
4.58HisLeu: 4.58 ± 1.234
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.527HisArg: 1.527 ± 1.147
0.0HisSer: 0.0 ± 0.0
1.527HisThr: 1.527 ± 1.059
3.053HisVal: 3.053 ± 2.294
3.053HisTrp: 3.053 ± 0.088
1.527HisTyr: 1.527 ± 1.059
0.0HisXaa: 0.0 ± 0.0
Ile
3.053IleAla: 3.053 ± 0.088
1.527IleCys: 1.527 ± 1.147
3.053IleAsp: 3.053 ± 2.294
1.527IleGlu: 1.527 ± 1.147
6.107IlePhe: 6.107 ± 2.381
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
6.107IleIle: 6.107 ± 0.175
3.053IleLys: 3.053 ± 0.088
6.107IleLeu: 6.107 ± 2.381
0.0IleMet: 0.0 ± 0.0
7.634IleAsn: 7.634 ± 0.884
4.58IlePro: 4.58 ± 3.178
0.0IleGln: 0.0 ± 0.0
6.107IleArg: 6.107 ± 2.031
3.053IleSer: 3.053 ± 0.088
4.58IleThr: 4.58 ± 0.972
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.58LysAla: 4.58 ± 0.972
0.0LysCys: 0.0 ± 0.0
4.58LysAsp: 4.58 ± 0.972
3.053LysGlu: 3.053 ± 0.088
1.527LysPhe: 1.527 ± 1.147
1.527LysGly: 1.527 ± 1.147
1.527LysHis: 1.527 ± 1.059
3.053LysIle: 3.053 ± 0.088
1.527LysLys: 1.527 ± 1.147
3.053LysLeu: 3.053 ± 2.294
6.107LysMet: 6.107 ± 1.582
1.527LysAsn: 1.527 ± 1.147
4.58LysPro: 4.58 ± 0.972
0.0LysGln: 0.0 ± 0.0
9.16LysArg: 9.16 ± 1.943
4.58LysSer: 4.58 ± 1.234
3.053LysThr: 3.053 ± 0.088
3.053LysVal: 3.053 ± 0.088
0.0LysTrp: 0.0 ± 0.0
3.053LysTyr: 3.053 ± 0.088
0.0LysXaa: 0.0 ± 0.0
Leu
1.527LeuAla: 1.527 ± 1.147
3.053LeuCys: 3.053 ± 0.088
1.527LeuAsp: 1.527 ± 1.147
1.527LeuGlu: 1.527 ± 1.147
3.053LeuPhe: 3.053 ± 2.294
1.527LeuGly: 1.527 ± 1.059
0.0LeuHis: 0.0 ± 0.0
4.58LeuIle: 4.58 ± 1.234
6.107LeuLys: 6.107 ± 2.381
0.0LeuLeu: 0.0 ± 0.0
0.0LeuMet: 0.0 ± 0.0
4.58LeuAsn: 4.58 ± 0.972
6.107LeuPro: 6.107 ± 2.381
4.58LeuGln: 4.58 ± 1.234
4.58LeuArg: 4.58 ± 1.234
4.58LeuSer: 4.58 ± 1.234
4.58LeuThr: 4.58 ± 3.178
1.527LeuVal: 1.527 ± 1.059
1.527LeuTrp: 1.527 ± 1.147
1.527LeuTyr: 1.527 ± 1.059
0.0LeuXaa: 0.0 ± 0.0
Met
1.527MetAla: 1.527 ± 1.147
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.527MetGlu: 1.527 ± 1.147
3.053MetPhe: 3.053 ± 2.118
0.0MetGly: 0.0 ± 0.0
1.527MetHis: 1.527 ± 1.059
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.527MetLeu: 1.527 ± 1.059
0.0MetMet: 0.0 ± 0.0
1.527MetAsn: 1.527 ± 1.059
1.527MetPro: 1.527 ± 1.059
0.0MetGln: 0.0 ± 0.0
3.053MetArg: 3.053 ± 2.118
3.053MetSer: 3.053 ± 0.088
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.527MetTyr: 1.527 ± 1.059
0.0MetXaa: 0.0 ± 0.0
Asn
4.58AsnAla: 4.58 ± 3.178
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
3.053AsnGlu: 3.053 ± 0.088
4.58AsnPhe: 4.58 ± 0.972
7.634AsnGly: 7.634 ± 3.528
1.527AsnHis: 1.527 ± 1.059
1.527AsnIle: 1.527 ± 1.059
3.053AsnLys: 3.053 ± 0.088
3.053AsnLeu: 3.053 ± 0.088
0.0AsnMet: 0.0 ± 0.0
4.58AsnAsn: 4.58 ± 3.44
6.107AsnPro: 6.107 ± 2.031
1.527AsnGln: 1.527 ± 1.059
4.58AsnArg: 4.58 ± 0.972
4.58AsnSer: 4.58 ± 0.972
4.58AsnThr: 4.58 ± 1.234
3.053AsnVal: 3.053 ± 0.088
1.527AsnTrp: 1.527 ± 1.147
1.527AsnTyr: 1.527 ± 1.059
0.0AsnXaa: 0.0 ± 0.0
Pro
1.527ProAla: 1.527 ± 1.059
0.0ProCys: 0.0 ± 0.0
7.634ProAsp: 7.634 ± 3.528
1.527ProGlu: 1.527 ± 1.059
1.527ProPhe: 1.527 ± 1.059
4.58ProGly: 4.58 ± 0.972
3.053ProHis: 3.053 ± 2.294
3.053ProIle: 3.053 ± 0.088
4.58ProLys: 4.58 ± 1.234
0.0ProLeu: 0.0 ± 0.0
1.527ProMet: 1.527 ± 1.059
4.58ProAsn: 4.58 ± 3.178
0.0ProPro: 0.0 ± 0.0
1.527ProGln: 1.527 ± 1.147
9.16ProArg: 9.16 ± 4.675
6.107ProSer: 6.107 ± 2.031
4.58ProThr: 4.58 ± 0.972
4.58ProVal: 4.58 ± 3.178
1.527ProTrp: 1.527 ± 1.059
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.58GlnAla: 4.58 ± 1.234
0.0GlnCys: 0.0 ± 0.0
1.527GlnAsp: 1.527 ± 1.059
1.527GlnGlu: 1.527 ± 1.059
3.053GlnPhe: 3.053 ± 0.088
3.053GlnGly: 3.053 ± 2.294
1.527GlnHis: 1.527 ± 1.147
3.053GlnIle: 3.053 ± 0.088
0.0GlnLys: 0.0 ± 0.0
3.053GlnLeu: 3.053 ± 2.294
1.527GlnMet: 1.527 ± 1.059
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
6.107GlnGln: 6.107 ± 2.381
3.053GlnArg: 3.053 ± 0.088
3.053GlnSer: 3.053 ± 2.118
0.0GlnThr: 0.0 ± 0.0
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.527GlnTyr: 1.527 ± 1.147
0.0GlnXaa: 0.0 ± 0.0
Arg
3.053ArgAla: 3.053 ± 0.088
1.527ArgCys: 1.527 ± 1.147
1.527ArgAsp: 1.527 ± 1.147
4.58ArgGlu: 4.58 ± 0.972
0.0ArgPhe: 0.0 ± 0.0
9.16ArgGly: 9.16 ± 0.263
0.0ArgHis: 0.0 ± 0.0
1.527ArgIle: 1.527 ± 1.147
9.16ArgLys: 9.16 ± 1.943
3.053ArgLeu: 3.053 ± 0.088
0.0ArgMet: 0.0 ± 0.0
1.527ArgAsn: 1.527 ± 1.147
7.634ArgPro: 7.634 ± 5.296
6.107ArgGln: 6.107 ± 2.381
9.16ArgArg: 9.16 ± 0.263
6.107ArgSer: 6.107 ± 2.381
10.687ArgThr: 10.687 ± 5.209
4.58ArgVal: 4.58 ± 0.972
3.053ArgTrp: 3.053 ± 0.088
4.58ArgTyr: 4.58 ± 1.234
0.0ArgXaa: 0.0 ± 0.0
Ser
9.16SerAla: 9.16 ± 1.943
0.0SerCys: 0.0 ± 0.0
6.107SerAsp: 6.107 ± 0.175
0.0SerGlu: 0.0 ± 0.0
3.053SerPhe: 3.053 ± 0.088
1.527SerGly: 1.527 ± 1.059
1.527SerHis: 1.527 ± 1.147
3.053SerIle: 3.053 ± 2.294
3.053SerLys: 3.053 ± 0.088
3.053SerLeu: 3.053 ± 2.294
1.527SerMet: 1.527 ± 1.059
4.58SerAsn: 4.58 ± 0.972
3.053SerPro: 3.053 ± 2.294
3.053SerGln: 3.053 ± 2.118
4.58SerArg: 4.58 ± 0.972
3.053SerSer: 3.053 ± 0.088
1.527SerThr: 1.527 ± 1.059
6.107SerVal: 6.107 ± 2.031
0.0SerTrp: 0.0 ± 0.0
3.053SerTyr: 3.053 ± 0.088
0.0SerXaa: 0.0 ± 0.0
Thr
7.634ThrAla: 7.634 ± 3.09
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
0.0ThrGlu: 0.0 ± 0.0
1.527ThrPhe: 1.527 ± 1.147
4.58ThrGly: 4.58 ± 0.972
1.527ThrHis: 1.527 ± 1.147
6.107ThrIle: 6.107 ± 0.175
4.58ThrLys: 4.58 ± 1.234
4.58ThrLeu: 4.58 ± 3.178
0.0ThrMet: 0.0 ± 0.0
3.053ThrAsn: 3.053 ± 2.118
4.58ThrPro: 4.58 ± 1.234
1.527ThrGln: 1.527 ± 1.059
3.053ThrArg: 3.053 ± 2.118
6.107ThrSer: 6.107 ± 4.237
7.634ThrThr: 7.634 ± 3.09
4.58ThrVal: 4.58 ± 0.972
0.0ThrTrp: 0.0 ± 0.0
4.58ThrTyr: 4.58 ± 3.178
0.0ThrXaa: 0.0 ± 0.0
Val
4.58ValAla: 4.58 ± 3.178
0.0ValCys: 0.0 ± 0.0
4.58ValAsp: 4.58 ± 1.234
3.053ValGlu: 3.053 ± 2.118
3.053ValPhe: 3.053 ± 2.294
3.053ValGly: 3.053 ± 0.088
1.527ValHis: 1.527 ± 1.059
6.107ValIle: 6.107 ± 0.175
3.053ValLys: 3.053 ± 0.088
1.527ValLeu: 1.527 ± 1.059
0.0ValMet: 0.0 ± 0.0
1.527ValAsn: 1.527 ± 1.059
3.053ValPro: 3.053 ± 0.088
1.527ValGln: 1.527 ± 1.147
4.58ValArg: 4.58 ± 3.178
3.053ValSer: 3.053 ± 0.088
3.053ValThr: 3.053 ± 0.088
3.053ValVal: 3.053 ± 2.294
1.527ValTrp: 1.527 ± 1.147
3.053ValTyr: 3.053 ± 0.088
0.0ValXaa: 0.0 ± 0.0
Trp
1.527TrpAla: 1.527 ± 1.059
0.0TrpCys: 0.0 ± 0.0
1.527TrpAsp: 1.527 ± 1.059
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.527TrpGly: 1.527 ± 1.147
0.0TrpHis: 0.0 ± 0.0
1.527TrpIle: 1.527 ± 1.147
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.527TrpPro: 1.527 ± 1.147
1.527TrpGln: 1.527 ± 1.147
1.527TrpArg: 1.527 ± 1.059
0.0TrpSer: 0.0 ± 0.0
1.527TrpThr: 1.527 ± 1.147
1.527TrpVal: 1.527 ± 1.147
0.0TrpTrp: 0.0 ± 0.0
1.527TrpTyr: 1.527 ± 1.059
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.527TyrAla: 1.527 ± 1.059
1.527TyrCys: 1.527 ± 1.147
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
4.58TyrPhe: 4.58 ± 0.972
3.053TyrGly: 3.053 ± 2.118
3.053TyrHis: 3.053 ± 0.088
1.527TyrIle: 1.527 ± 1.059
1.527TyrLys: 1.527 ± 1.059
6.107TyrLeu: 6.107 ± 4.587
1.527TyrMet: 1.527 ± 1.059
3.053TyrAsn: 3.053 ± 0.088
1.527TyrPro: 1.527 ± 1.147
0.0TyrGln: 0.0 ± 0.0
4.58TyrArg: 4.58 ± 0.972
3.053TyrSer: 3.053 ± 2.118
1.527TyrThr: 1.527 ± 1.147
3.053TyrVal: 3.053 ± 0.088
1.527TyrTrp: 1.527 ± 1.059
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (656 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski