Amino acid dipepetide frequency for Pantoea alhagi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.266AlaAla: 11.266 ± 0.149	1.092AlaCys: 1.092 ± 0.029	4.907AlaAsp: 4.907 ± 0.077	6.172AlaGlu: 6.172 ± 0.078	3.605AlaPhe: 3.605 ± 0.063	7.919AlaGly: 7.919 ± 0.114	1.953AlaHis: 1.953 ± 0.041	5.856AlaIle: 5.856 ± 0.084	3.445AlaLys: 3.445 ± 0.071	12.99AlaLeu: 12.99 ± 0.118	3.023AlaMet: 3.023 ± 0.057	2.978AlaAsn: 2.978 ± 0.054	3.842AlaPro: 3.842 ± 0.065	5.146AlaGln: 5.146 ± 0.081	6.142AlaArg: 6.142 ± 0.097	5.846AlaSer: 5.846 ± 0.072	4.834AlaThr: 4.834 ± 0.067	6.817AlaVal: 6.817 ± 0.088	1.744AlaTrp: 1.744 ± 0.041	1.892AlaTyr: 1.892 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.923CysAla: 0.923 ± 0.027	0.171CysCys: 0.171 ± 0.012	0.538CysAsp: 0.538 ± 0.025	0.543CysGlu: 0.543 ± 0.022	0.431CysPhe: 0.431 ± 0.02	1.046CysGly: 1.046 ± 0.031	0.323CysHis: 0.323 ± 0.019	0.535CysIle: 0.535 ± 0.023	0.271CysLys: 0.271 ± 0.015	1.014CysLeu: 1.014 ± 0.029	0.23CysMet: 0.23 ± 0.013	0.29CysAsn: 0.29 ± 0.016	0.448CysPro: 0.448 ± 0.021	0.463CysGln: 0.463 ± 0.022	0.638CysArg: 0.638 ± 0.025	0.616CysSer: 0.616 ± 0.022	0.439CysThr: 0.439 ± 0.019	0.676CysVal: 0.676 ± 0.026	0.196CysTrp: 0.196 ± 0.013	0.311CysTyr: 0.311 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.13AspAla: 5.13 ± 0.074	0.474AspCys: 0.474 ± 0.02	2.685AspAsp: 2.685 ± 0.05	3.53AspGlu: 3.53 ± 0.058	2.098AspPhe: 2.098 ± 0.042	3.601AspGly: 3.601 ± 0.059	0.972AspHis: 0.972 ± 0.027	3.257AspIle: 3.257 ± 0.044	2.253AspLys: 2.253 ± 0.05	4.696AspLeu: 4.696 ± 0.07	1.326AspMet: 1.326 ± 0.035	2.197AspAsn: 2.197 ± 0.044	2.188AspPro: 2.188 ± 0.041	1.553AspGln: 1.553 ± 0.04	3.15AspArg: 3.15 ± 0.057	2.796AspSer: 2.796 ± 0.049	2.352AspThr: 2.352 ± 0.039	3.399AspVal: 3.399 ± 0.058	0.798AspTrp: 0.798 ± 0.027	1.88AspTyr: 1.88 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.845GluAla: 5.845 ± 0.072	0.42GluCys: 0.42 ± 0.018	2.322GluAsp: 2.322 ± 0.048	3.493GluGlu: 3.493 ± 0.065	1.707GluPhe: 1.707 ± 0.038	3.541GluGly: 3.541 ± 0.055	1.297GluHis: 1.297 ± 0.034	3.332GluIle: 3.332 ± 0.054	3.234GluLys: 3.234 ± 0.055	5.89GluLeu: 5.89 ± 0.081	1.836GluMet: 1.836 ± 0.037	2.346GluAsn: 2.346 ± 0.042	2.11GluPro: 2.11 ± 0.047	3.724GluGln: 3.724 ± 0.06	3.723GluArg: 3.723 ± 0.056	2.918GluSer: 2.918 ± 0.051	3.006GluThr: 3.006 ± 0.049	3.743GluVal: 3.743 ± 0.059	0.8GluTrp: 0.8 ± 0.026	1.33GluTyr: 1.33 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.612PheAla: 3.612 ± 0.06	0.546PheCys: 0.546 ± 0.02	2.236PheAsp: 2.236 ± 0.042	1.606PheGlu: 1.606 ± 0.038	1.632PhePhe: 1.632 ± 0.047	3.04PheGly: 3.04 ± 0.063	0.817PheHis: 0.817 ± 0.028	2.541PheIle: 2.541 ± 0.045	1.161PheLys: 1.161 ± 0.032	3.304PheLeu: 3.304 ± 0.067	0.958PheMet: 0.958 ± 0.034	1.759PheAsn: 1.759 ± 0.043	1.544PhePro: 1.544 ± 0.044	1.244PheGln: 1.244 ± 0.031	1.98PheArg: 1.98 ± 0.045	3.147PheSer: 3.147 ± 0.048	2.306PheThr: 2.306 ± 0.045	2.312PheVal: 2.312 ± 0.046	0.666PheTrp: 0.666 ± 0.023	1.191PheTyr: 1.191 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	6.364GlyAla: 6.364 ± 0.096	0.93GlyCys: 0.93 ± 0.033	3.619GlyAsp: 3.619 ± 0.064	4.632GlyGlu: 4.632 ± 0.073	3.213GlyPhe: 3.213 ± 0.052	5.291GlyGly: 5.291 ± 0.096	1.618GlyHis: 1.618 ± 0.039	4.842GlyIle: 4.842 ± 0.065	3.81GlyLys: 3.81 ± 0.064	7.681GlyLeu: 7.681 ± 0.074	2.333GlyMet: 2.333 ± 0.045	2.718GlyAsn: 2.718 ± 0.056	2.068GlyPro: 2.068 ± 0.043	2.97GlyGln: 2.97 ± 0.057	3.96GlyArg: 3.96 ± 0.062	4.359GlySer: 4.359 ± 0.071	3.657GlyThr: 3.657 ± 0.056	5.361GlyVal: 5.361 ± 0.066	1.342GlyTrp: 1.342 ± 0.038	2.556GlyTyr: 2.556 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.018HisAla: 2.018 ± 0.034	0.318HisCys: 0.318 ± 0.017	1.145HisAsp: 1.145 ± 0.032	1.128HisGlu: 1.128 ± 0.035	1.091HisPhe: 1.091 ± 0.028	1.729HisGly: 1.729 ± 0.043	0.77HisHis: 0.77 ± 0.028	1.341HisIle: 1.341 ± 0.033	0.717HisLys: 0.717 ± 0.028	2.302HisLeu: 2.302 ± 0.048	0.525HisMet: 0.525 ± 0.025	0.841HisAsn: 0.841 ± 0.026	1.287HisPro: 1.287 ± 0.035	1.387HisGln: 1.387 ± 0.035	1.304HisArg: 1.304 ± 0.033	1.301HisSer: 1.301 ± 0.035	1.071HisThr: 1.071 ± 0.032	1.226HisVal: 1.226 ± 0.026	0.417HisTrp: 0.417 ± 0.019	0.925HisTyr: 0.925 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	6.557IleAla: 6.557 ± 0.082	0.64IleCys: 0.64 ± 0.022	3.51IleAsp: 3.51 ± 0.063	3.323IleGlu: 3.323 ± 0.056	1.967IlePhe: 1.967 ± 0.044	4.515IleGly: 4.515 ± 0.072	1.195IleHis: 1.195 ± 0.036	3.277IleIle: 3.277 ± 0.06	2.253IleLys: 2.253 ± 0.044	4.716IleLeu: 4.716 ± 0.071	1.33IleMet: 1.33 ± 0.037	2.622IleAsn: 2.622 ± 0.053	2.474IlePro: 2.474 ± 0.048	1.811IleGln: 1.811 ± 0.04	2.95IleArg: 2.95 ± 0.051	3.725IleSer: 3.725 ± 0.062	3.487IleThr: 3.487 ± 0.052	3.775IleVal: 3.775 ± 0.059	0.727IleTrp: 0.727 ± 0.027	1.428IleTyr: 1.428 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.082LysAla: 4.082 ± 0.079	0.203LysCys: 0.203 ± 0.014	1.817LysAsp: 1.817 ± 0.04	2.267LysGlu: 2.267 ± 0.052	1.02LysPhe: 1.02 ± 0.03	2.713LysGly: 2.713 ± 0.057	0.786LysHis: 0.786 ± 0.027	2.263LysIle: 2.263 ± 0.049	2.08LysLys: 2.08 ± 0.049	3.967LysLeu: 3.967 ± 0.053	1.149LysMet: 1.149 ± 0.026	1.606LysAsn: 1.606 ± 0.037	2.041LysPro: 2.041 ± 0.05	1.999LysGln: 1.999 ± 0.04	2.456LysArg: 2.456 ± 0.049	2.169LysSer: 2.169 ± 0.044	2.284LysThr: 2.284 ± 0.049	2.7LysVal: 2.7 ± 0.052	0.432LysTrp: 0.432 ± 0.018	0.979LysTyr: 0.979 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	12.273LeuAla: 12.273 ± 0.131	1.278LeuCys: 1.278 ± 0.034	5.548LeuAsp: 5.548 ± 0.081	5.512LeuGlu: 5.512 ± 0.076	4.462LeuPhe: 4.462 ± 0.078	7.255LeuGly: 7.255 ± 0.098	2.39LeuHis: 2.39 ± 0.048	6.04LeuIle: 6.04 ± 0.079	4.352LeuLys: 4.352 ± 0.068	13.291LeuLeu: 13.291 ± 0.16	3.134LeuMet: 3.134 ± 0.061	4.197LeuAsn: 4.197 ± 0.063	6.037LeuPro: 6.037 ± 0.076	4.98LeuGln: 4.98 ± 0.087	6.632LeuArg: 6.632 ± 0.089	7.636LeuSer: 7.636 ± 0.079	6.615LeuThr: 6.615 ± 0.089	7.028LeuVal: 7.028 ± 0.093	1.462LeuTrp: 1.462 ± 0.035	2.583LeuTyr: 2.583 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.957MetAla: 2.957 ± 0.049	0.158MetCys: 0.158 ± 0.012	1.159MetAsp: 1.159 ± 0.027	1.274MetGlu: 1.274 ± 0.033	0.817MetPhe: 0.817 ± 0.028	1.795MetGly: 1.795 ± 0.038	0.554MetHis: 0.554 ± 0.023	1.392MetIle: 1.392 ± 0.043	1.33MetLys: 1.33 ± 0.038	3.434MetLeu: 3.434 ± 0.06	0.895MetMet: 0.895 ± 0.026	1.094MetAsn: 1.094 ± 0.029	1.374MetPro: 1.374 ± 0.033	1.369MetGln: 1.369 ± 0.036	1.536MetArg: 1.536 ± 0.03	1.851MetSer: 1.851 ± 0.037	1.688MetThr: 1.688 ± 0.035	1.89MetVal: 1.89 ± 0.035	0.238MetTrp: 0.238 ± 0.015	0.478MetTyr: 0.478 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.648AsnAla: 3.648 ± 0.059	0.331AsnCys: 0.331 ± 0.017	1.959AsnAsp: 1.959 ± 0.042	1.894AsnGlu: 1.894 ± 0.041	1.326AsnPhe: 1.326 ± 0.036	3.062AsnGly: 3.062 ± 0.066	0.803AsnHis: 0.803 ± 0.027	2.219AsnIle: 2.219 ± 0.047	1.448AsnLys: 1.448 ± 0.039	3.504AsnLeu: 3.504 ± 0.055	0.916AsnMet: 0.916 ± 0.027	1.601AsnAsn: 1.601 ± 0.05	1.994AsnPro: 1.994 ± 0.042	1.732AsnGln: 1.732 ± 0.047	2.109AsnArg: 2.109 ± 0.037	2.118AsnSer: 2.118 ± 0.051	1.752AsnThr: 1.752 ± 0.046	2.35AsnVal: 2.35 ± 0.048	0.591AsnTrp: 0.591 ± 0.024	1.138AsnTyr: 1.138 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	4.858ProAla: 4.858 ± 0.068	0.371ProCys: 0.371 ± 0.019	2.768ProAsp: 2.768 ± 0.05	3.395ProGlu: 3.395 ± 0.06	1.759ProPhe: 1.759 ± 0.038	3.619ProGly: 3.619 ± 0.055	1.137ProHis: 1.137 ± 0.033	1.716ProIle: 1.716 ± 0.04	1.274ProLys: 1.274 ± 0.038	5.489ProLeu: 5.489 ± 0.069	1.067ProMet: 1.067 ± 0.031	1.213ProAsn: 1.213 ± 0.035	1.772ProPro: 1.772 ± 0.038	2.635ProGln: 2.635 ± 0.051	2.084ProArg: 2.084 ± 0.043	2.004ProSer: 2.004 ± 0.043	1.985ProThr: 1.985 ± 0.04	4.048ProVal: 4.048 ± 0.06	0.775ProTrp: 0.775 ± 0.026	1.169ProTyr: 1.169 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.338GlnAla: 5.338 ± 0.079	0.351GlnCys: 0.351 ± 0.018	1.957GlnAsp: 1.957 ± 0.042	2.397GlnGlu: 2.397 ± 0.051	1.444GlnPhe: 1.444 ± 0.034	3.363GlnGly: 3.363 ± 0.061	1.475GlnHis: 1.475 ± 0.039	2.324GlnIle: 2.324 ± 0.044	1.687GlnLys: 1.687 ± 0.041	5.837GlnLeu: 5.837 ± 0.092	1.267GlnMet: 1.267 ± 0.029	1.472GlnAsn: 1.472 ± 0.035	2.869GlnPro: 2.869 ± 0.06	4.646GlnGln: 4.646 ± 0.112	3.775GlnArg: 3.775 ± 0.076	2.384GlnSer: 2.384 ± 0.048	2.266GlnThr: 2.266 ± 0.043	3.106GlnVal: 3.106 ± 0.055	0.657GlnTrp: 0.657 ± 0.023	1.142GlnTyr: 1.142 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	5.07ArgAla: 5.07 ± 0.072	0.598ArgCys: 0.598 ± 0.021	3.065ArgAsp: 3.065 ± 0.057	3.801ArgGlu: 3.801 ± 0.07	2.713ArgPhe: 2.713 ± 0.057	3.452ArgGly: 3.452 ± 0.06	1.629ArgHis: 1.629 ± 0.037	3.489ArgIle: 3.489 ± 0.054	2.19ArgLys: 2.19 ± 0.051	7.189ArgLeu: 7.189 ± 0.097	1.651ArgMet: 1.651 ± 0.031	2.118ArgAsn: 2.118 ± 0.039	2.422ArgPro: 2.422 ± 0.045	3.662ArgGln: 3.662 ± 0.067	3.887ArgArg: 3.887 ± 0.07	3.025ArgSer: 3.025 ± 0.059	2.557ArgThr: 2.557 ± 0.05	3.87ArgVal: 3.87 ± 0.062	1.123ArgTrp: 1.123 ± 0.036	2.35ArgTyr: 2.35 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.12SerAla: 6.12 ± 0.073	0.557SerCys: 0.557 ± 0.02	3.171SerAsp: 3.171 ± 0.052	3.386SerGlu: 3.386 ± 0.051	2.304SerPhe: 2.304 ± 0.044	5.391SerGly: 5.391 ± 0.08	1.429SerHis: 1.429 ± 0.032	2.682SerIle: 2.682 ± 0.048	1.958SerLys: 1.958 ± 0.04	6.947SerLeu: 6.947 ± 0.089	1.457SerMet: 1.457 ± 0.036	1.914SerAsn: 1.914 ± 0.046	2.575SerPro: 2.575 ± 0.043	2.569SerGln: 2.569 ± 0.053	3.539SerArg: 3.539 ± 0.05	3.652SerSer: 3.652 ± 0.066	2.781SerThr: 2.781 ± 0.052	4.199SerVal: 4.199 ± 0.062	1.149SerTrp: 1.149 ± 0.037	1.614SerTyr: 1.614 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	4.959ThrAla: 4.959 ± 0.071	0.435ThrCys: 0.435 ± 0.017	2.398ThrAsp: 2.398 ± 0.043	2.586ThrGlu: 2.586 ± 0.048	1.928ThrPhe: 1.928 ± 0.039	4.387ThrGly: 4.387 ± 0.061	1.274ThrHis: 1.274 ± 0.031	2.739ThrIle: 2.739 ± 0.051	1.32ThrLys: 1.32 ± 0.04	7.693ThrLeu: 7.693 ± 0.097	1.087ThrMet: 1.087 ± 0.029	1.5ThrAsn: 1.5 ± 0.043	3.13ThrPro: 3.13 ± 0.051	2.357ThrGln: 2.357 ± 0.042	3.088ThrArg: 3.088 ± 0.054	2.872ThrSer: 2.872 ± 0.055	2.617ThrThr: 2.617 ± 0.044	3.65ThrVal: 3.65 ± 0.061	0.746ThrTrp: 0.746 ± 0.024	1.018ThrTyr: 1.018 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	6.998ValAla: 6.998 ± 0.084	0.676ValCys: 0.676 ± 0.027	3.423ValAsp: 3.423 ± 0.052	3.869ValGlu: 3.869 ± 0.056	2.271ValPhe: 2.271 ± 0.045	4.545ValGly: 4.545 ± 0.067	1.192ValHis: 1.192 ± 0.032	4.351ValIle: 4.351 ± 0.061	2.897ValLys: 2.897 ± 0.051	7.172ValLeu: 7.172 ± 0.093	2.118ValMet: 2.118 ± 0.04	2.623ValAsn: 2.623 ± 0.048	2.984ValPro: 2.984 ± 0.053	2.428ValGln: 2.428 ± 0.046	3.773ValArg: 3.773 ± 0.064	4.499ValSer: 4.499 ± 0.06	4.269ValThr: 4.269 ± 0.067	5.107ValVal: 5.107 ± 0.079	0.944ValTrp: 0.944 ± 0.028	1.536ValTyr: 1.536 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.02TrpAla: 1.02 ± 0.03	0.187TrpCys: 0.187 ± 0.012	0.637TrpAsp: 0.637 ± 0.025	0.59TrpGlu: 0.59 ± 0.022	0.723TrpPhe: 0.723 ± 0.027	0.891TrpGly: 0.891 ± 0.028	0.494TrpHis: 0.494 ± 0.024	0.751TrpIle: 0.751 ± 0.029	0.478TrpLys: 0.478 ± 0.021	2.616TrpLeu: 2.616 ± 0.053	0.394TrpMet: 0.394 ± 0.018	0.466TrpAsn: 0.466 ± 0.019	0.714TrpPro: 0.714 ± 0.028	1.373TrpGln: 1.373 ± 0.045	1.228TrpArg: 1.228 ± 0.032	0.845TrpSer: 0.845 ± 0.03	0.552TrpThr: 0.552 ± 0.02	0.865TrpVal: 0.865 ± 0.03	0.24TrpTrp: 0.24 ± 0.012	0.425TrpTyr: 0.425 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.432TyrAla: 2.432 ± 0.042	0.365TyrCys: 0.365 ± 0.018	1.472TyrAsp: 1.472 ± 0.04	1.223TyrGlu: 1.223 ± 0.036	1.089TyrPhe: 1.089 ± 0.026	2.169TyrGly: 2.169 ± 0.048	0.731TyrHis: 0.731 ± 0.025	1.332TyrIle: 1.332 ± 0.035	0.856TyrLys: 0.856 ± 0.029	2.973TyrLeu: 2.973 ± 0.048	0.586TyrMet: 0.586 ± 0.021	0.941TyrAsn: 0.941 ± 0.029	1.267TyrPro: 1.267 ± 0.034	1.707TyrGln: 1.707 ± 0.035	1.905TyrArg: 1.905 ± 0.04	1.632TyrSer: 1.632 ± 0.037	1.266TyrThr: 1.266 ± 0.035	1.557TyrVal: 1.557 ± 0.039	0.442TyrTrp: 0.442 ± 0.02	0.887TyrTyr: 0.887 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3878 proteins (1212343 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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