Amino acid dipepetide frequency for Plautia stali symbiont

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.325AlaAla: 12.325 ± 0.139	1.12AlaCys: 1.12 ± 0.034	5.42AlaAsp: 5.42 ± 0.081	6.065AlaGlu: 6.065 ± 0.083	3.553AlaPhe: 3.553 ± 0.05	8.245AlaGly: 8.245 ± 0.102	2.13AlaHis: 2.13 ± 0.042	5.855AlaIle: 5.855 ± 0.073	3.498AlaLys: 3.498 ± 0.064	13.186AlaLeu: 13.186 ± 0.108	3.237AlaMet: 3.237 ± 0.052	2.859AlaAsn: 2.859 ± 0.05	4.123AlaPro: 4.123 ± 0.072	5.718AlaGln: 5.718 ± 0.071	6.533AlaArg: 6.533 ± 0.091	6.15AlaSer: 6.15 ± 0.079	4.891AlaThr: 4.891 ± 0.068	6.982AlaVal: 6.982 ± 0.094	1.582AlaTrp: 1.582 ± 0.036	2.035AlaTyr: 2.035 ± 0.044	0.002AlaXaa: 0.002 ± 0.001
Cys	1.058CysAla: 1.058 ± 0.032	0.222CysCys: 0.222 ± 0.015	0.558CysAsp: 0.558 ± 0.026	0.535CysGlu: 0.535 ± 0.02	0.455CysPhe: 0.455 ± 0.02	1.083CysGly: 1.083 ± 0.03	0.316CysHis: 0.316 ± 0.019	0.51CysIle: 0.51 ± 0.023	0.259CysLys: 0.259 ± 0.017	1.008CysLeu: 1.008 ± 0.033	0.271CysMet: 0.271 ± 0.017	0.308CysAsn: 0.308 ± 0.018	0.476CysPro: 0.476 ± 0.02	0.49CysGln: 0.49 ± 0.017	0.737CysArg: 0.737 ± 0.028	0.679CysSer: 0.679 ± 0.026	0.467CysThr: 0.467 ± 0.021	0.743CysVal: 0.743 ± 0.028	0.238CysTrp: 0.238 ± 0.014	0.299CysTyr: 0.299 ± 0.017	0.002CysXaa: 0.002 ± 0.001
Asp	5.838AspAla: 5.838 ± 0.069	0.54AspCys: 0.54 ± 0.022	3.088AspAsp: 3.088 ± 0.058	3.359AspGlu: 3.359 ± 0.054	2.12AspPhe: 2.12 ± 0.044	3.917AspGly: 3.917 ± 0.062	1.082AspHis: 1.082 ± 0.032	3.185AspIle: 3.185 ± 0.057	2.284AspLys: 2.284 ± 0.055	4.683AspLeu: 4.683 ± 0.068	1.321AspMet: 1.321 ± 0.037	2.093AspAsn: 2.093 ± 0.05	2.121AspPro: 2.121 ± 0.046	1.873AspGln: 1.873 ± 0.035	3.059AspArg: 3.059 ± 0.058	2.892AspSer: 2.892 ± 0.048	2.432AspThr: 2.432 ± 0.048	3.833AspVal: 3.833 ± 0.057	0.841AspTrp: 0.841 ± 0.027	1.83AspTyr: 1.83 ± 0.04	0.002AspXaa: 0.002 ± 0.001
Glu	5.556GluAla: 5.556 ± 0.082	0.379GluCys: 0.379 ± 0.017	2.17GluAsp: 2.17 ± 0.044	3.007GluGlu: 3.007 ± 0.063	1.685GluPhe: 1.685 ± 0.04	3.207GluGly: 3.207 ± 0.06	1.266GluHis: 1.266 ± 0.036	3.062GluIle: 3.062 ± 0.067	2.761GluLys: 2.761 ± 0.053	5.821GluLeu: 5.821 ± 0.085	1.703GluMet: 1.703 ± 0.042	2.062GluAsn: 2.062 ± 0.043	1.946GluPro: 1.946 ± 0.048	3.453GluGln: 3.453 ± 0.059	3.566GluArg: 3.566 ± 0.062	2.639GluSer: 2.639 ± 0.046	2.742GluThr: 2.742 ± 0.059	3.769GluVal: 3.769 ± 0.063	0.698GluTrp: 0.698 ± 0.024	1.212GluTyr: 1.212 ± 0.032	0.002GluXaa: 0.002 ± 0.001
Phe	3.806PheAla: 3.806 ± 0.06	0.525PheCys: 0.525 ± 0.019	2.375PheAsp: 2.375 ± 0.046	1.581PheGlu: 1.581 ± 0.043	1.493PhePhe: 1.493 ± 0.042	3.081PheGly: 3.081 ± 0.058	0.822PheHis: 0.822 ± 0.027	2.273PheIle: 2.273 ± 0.047	1.192PheLys: 1.192 ± 0.034	3.132PheLeu: 3.132 ± 0.061	0.957PheMet: 0.957 ± 0.029	1.586PheAsn: 1.586 ± 0.043	1.57PhePro: 1.57 ± 0.036	1.234PheGln: 1.234 ± 0.034	1.948PheArg: 1.948 ± 0.045	3.031PheSer: 3.031 ± 0.053	2.218PheThr: 2.218 ± 0.042	2.388PheVal: 2.388 ± 0.051	0.572PheTrp: 0.572 ± 0.027	1.06PheTyr: 1.06 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	6.579GlyAla: 6.579 ± 0.084	0.986GlyCys: 0.986 ± 0.03	3.876GlyAsp: 3.876 ± 0.066	4.468GlyGlu: 4.468 ± 0.067	3.228GlyPhe: 3.228 ± 0.052	5.313GlyGly: 5.313 ± 0.082	1.715GlyHis: 1.715 ± 0.041	4.616GlyIle: 4.616 ± 0.069	3.764GlyLys: 3.764 ± 0.066	7.378GlyLeu: 7.378 ± 0.095	2.401GlyMet: 2.401 ± 0.052	2.714GlyAsn: 2.714 ± 0.056	1.992GlyPro: 1.992 ± 0.045	3.104GlyGln: 3.104 ± 0.05	4.063GlyArg: 4.063 ± 0.065	4.337GlySer: 4.337 ± 0.076	3.547GlyThr: 3.547 ± 0.055	5.603GlyVal: 5.603 ± 0.076	1.353GlyTrp: 1.353 ± 0.038	2.508GlyTyr: 2.508 ± 0.052	0.002GlyXaa: 0.002 ± 0.001
His	2.241HisAla: 2.241 ± 0.047	0.358HisCys: 0.358 ± 0.018	1.224HisAsp: 1.224 ± 0.033	1.093HisGlu: 1.093 ± 0.03	1.083HisPhe: 1.083 ± 0.031	1.85HisGly: 1.85 ± 0.042	0.853HisHis: 0.853 ± 0.03	1.286HisIle: 1.286 ± 0.034	0.768HisLys: 0.768 ± 0.028	2.365HisLeu: 2.365 ± 0.05	0.559HisMet: 0.559 ± 0.022	0.802HisAsn: 0.802 ± 0.027	1.35HisPro: 1.35 ± 0.033	1.37HisGln: 1.37 ± 0.039	1.454HisArg: 1.454 ± 0.038	1.437HisSer: 1.437 ± 0.04	1.075HisThr: 1.075 ± 0.034	1.263HisVal: 1.263 ± 0.032	0.466HisTrp: 0.466 ± 0.022	0.902HisTyr: 0.902 ± 0.027	0.002HisXaa: 0.002 ± 0.001
Ile	6.529IleAla: 6.529 ± 0.086	0.661IleCys: 0.661 ± 0.026	3.536IleAsp: 3.536 ± 0.051	3.063IleGlu: 3.063 ± 0.057	1.733IlePhe: 1.733 ± 0.043	4.371IleGly: 4.371 ± 0.062	1.137IleHis: 1.137 ± 0.032	2.922IleIle: 2.922 ± 0.06	2.062IleLys: 2.062 ± 0.044	4.447IleLeu: 4.447 ± 0.061	1.201IleMet: 1.201 ± 0.033	2.469IleAsn: 2.469 ± 0.05	2.369IlePro: 2.369 ± 0.05	1.716IleGln: 1.716 ± 0.037	2.901IleArg: 2.901 ± 0.045	3.596IleSer: 3.596 ± 0.051	3.359IleThr: 3.359 ± 0.057	3.747IleVal: 3.747 ± 0.06	0.659IleTrp: 0.659 ± 0.029	1.446IleTyr: 1.446 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.997LysAla: 3.997 ± 0.067	0.24LysCys: 0.24 ± 0.016	1.807LysAsp: 1.807 ± 0.048	1.945LysGlu: 1.945 ± 0.05	1.006LysPhe: 1.006 ± 0.031	2.724LysGly: 2.724 ± 0.059	0.778LysHis: 0.778 ± 0.024	2.008LysIle: 2.008 ± 0.047	1.948LysLys: 1.948 ± 0.055	3.859LysLeu: 3.859 ± 0.069	1.123LysMet: 1.123 ± 0.033	1.475LysAsn: 1.475 ± 0.041	2.049LysPro: 2.049 ± 0.039	1.949LysGln: 1.949 ± 0.036	2.551LysArg: 2.551 ± 0.051	2.125LysSer: 2.125 ± 0.045	2.247LysThr: 2.247 ± 0.048	2.771LysVal: 2.771 ± 0.06	0.402LysTrp: 0.402 ± 0.019	0.97LysTyr: 0.97 ± 0.031	0.002LysXaa: 0.002 ± 0.001
Leu	12.523LeuAla: 12.523 ± 0.133	1.26LeuCys: 1.26 ± 0.035	5.539LeuAsp: 5.539 ± 0.08	5.242LeuGlu: 5.242 ± 0.073	4.118LeuPhe: 4.118 ± 0.058	7.302LeuGly: 7.302 ± 0.085	2.489LeuHis: 2.489 ± 0.048	5.684LeuIle: 5.684 ± 0.072	4.157LeuLys: 4.157 ± 0.068	12.805LeuLeu: 12.805 ± 0.177	3.033LeuMet: 3.033 ± 0.051	4.155LeuAsn: 4.155 ± 0.067	5.93LeuPro: 5.93 ± 0.07	5.281LeuGln: 5.281 ± 0.077	6.803LeuArg: 6.803 ± 0.081	7.431LeuSer: 7.431 ± 0.092	6.346LeuThr: 6.346 ± 0.076	7.195LeuVal: 7.195 ± 0.105	1.437LeuTrp: 1.437 ± 0.044	2.472LeuTyr: 2.472 ± 0.044	0.004LeuXaa: 0.004 ± 0.002
Met	3.051MetAla: 3.051 ± 0.058	0.199MetCys: 0.199 ± 0.013	1.21MetAsp: 1.21 ± 0.032	1.222MetGlu: 1.222 ± 0.037	0.83MetPhe: 0.83 ± 0.026	1.758MetGly: 1.758 ± 0.041	0.56MetHis: 0.56 ± 0.024	1.508MetIle: 1.508 ± 0.036	1.333MetLys: 1.333 ± 0.035	3.329MetLeu: 3.329 ± 0.059	0.89MetMet: 0.89 ± 0.033	0.992MetAsn: 0.992 ± 0.034	1.42MetPro: 1.42 ± 0.037	1.371MetGln: 1.371 ± 0.034	1.665MetArg: 1.665 ± 0.043	1.821MetSer: 1.821 ± 0.038	1.726MetThr: 1.726 ± 0.038	2.012MetVal: 2.012 ± 0.045	0.281MetTrp: 0.281 ± 0.017	0.444MetTyr: 0.444 ± 0.02	0.001MetXaa: 0.001 ± 0.001
Asn	3.505AsnAla: 3.505 ± 0.066	0.363AsnCys: 0.363 ± 0.02	1.897AsnAsp: 1.897 ± 0.039	1.617AsnGlu: 1.617 ± 0.036	1.302AsnPhe: 1.302 ± 0.032	2.923AsnGly: 2.923 ± 0.052	0.812AsnHis: 0.812 ± 0.026	1.995AsnIle: 1.995 ± 0.046	1.311AsnLys: 1.311 ± 0.039	3.465AsnLeu: 3.465 ± 0.059	0.804AsnMet: 0.804 ± 0.03	1.396AsnAsn: 1.396 ± 0.042	2.047AsnPro: 2.047 ± 0.046	1.69AsnGln: 1.69 ± 0.041	2.061AsnArg: 2.061 ± 0.043	2.021AsnSer: 2.021 ± 0.045	1.714AsnThr: 1.714 ± 0.044	2.402AsnVal: 2.402 ± 0.051	0.538AsnTrp: 0.538 ± 0.021	1.002AsnTyr: 1.002 ± 0.036	0.001AsnXaa: 0.001 ± 0.001
Pro	5.33ProAla: 5.33 ± 0.072	0.389ProCys: 0.389 ± 0.019	2.756ProAsp: 2.756 ± 0.055	2.946ProGlu: 2.946 ± 0.055	1.775ProPhe: 1.775 ± 0.042	3.486ProGly: 3.486 ± 0.058	1.226ProHis: 1.226 ± 0.03	1.849ProIle: 1.849 ± 0.044	1.373ProLys: 1.373 ± 0.038	5.374ProLeu: 5.374 ± 0.077	1.157ProMet: 1.157 ± 0.034	1.234ProAsn: 1.234 ± 0.037	1.873ProPro: 1.873 ± 0.037	2.645ProGln: 2.645 ± 0.056	2.157ProArg: 2.157 ± 0.043	2.172ProSer: 2.172 ± 0.043	2.045ProThr: 2.045 ± 0.042	3.765ProVal: 3.765 ± 0.057	0.724ProTrp: 0.724 ± 0.026	1.149ProTyr: 1.149 ± 0.033	0.001ProXaa: 0.001 ± 0.001
Gln	5.502GlnAla: 5.502 ± 0.081	0.382GlnCys: 0.382 ± 0.018	2.043GlnAsp: 2.043 ± 0.04	2.1GlnGlu: 2.1 ± 0.047	1.545GlnPhe: 1.545 ± 0.037	3.309GlnGly: 3.309 ± 0.053	1.615GlnHis: 1.615 ± 0.042	2.307GlnIle: 2.307 ± 0.044	1.627GlnLys: 1.627 ± 0.037	6.259GlnLeu: 6.259 ± 0.084	1.314GlnMet: 1.314 ± 0.037	1.378GlnAsn: 1.378 ± 0.039	3.0GlnPro: 3.0 ± 0.056	4.897GlnGln: 4.897 ± 0.09	4.013GlnArg: 4.013 ± 0.067	2.365GlnSer: 2.365 ± 0.052	2.227GlnThr: 2.227 ± 0.046	3.241GlnVal: 3.241 ± 0.054	0.777GlnTrp: 0.777 ± 0.025	1.108GlnTyr: 1.108 ± 0.034	0.001GlnXaa: 0.001 ± 0.001
Arg	5.559ArgAla: 5.559 ± 0.078	0.746ArgCys: 0.746 ± 0.029	3.301ArgAsp: 3.301 ± 0.056	3.699ArgGlu: 3.699 ± 0.062	2.788ArgPhe: 2.788 ± 0.049	3.673ArgGly: 3.673 ± 0.062	1.81ArgHis: 1.81 ± 0.038	3.39ArgIle: 3.39 ± 0.06	2.217ArgLys: 2.217 ± 0.047	6.98ArgLeu: 6.98 ± 0.089	1.707ArgMet: 1.707 ± 0.036	2.073ArgAsn: 2.073 ± 0.046	2.457ArgPro: 2.457 ± 0.051	3.548ArgGln: 3.548 ± 0.063	4.132ArgArg: 4.132 ± 0.082	3.166ArgSer: 3.166 ± 0.058	2.547ArgThr: 2.547 ± 0.045	4.101ArgVal: 4.101 ± 0.058	1.187ArgTrp: 1.187 ± 0.034	2.284ArgTyr: 2.284 ± 0.045	0.002ArgXaa: 0.002 ± 0.001
Ser	6.509SerAla: 6.509 ± 0.085	0.576SerCys: 0.576 ± 0.022	3.275SerAsp: 3.275 ± 0.049	3.206SerGlu: 3.206 ± 0.057	2.198SerPhe: 2.198 ± 0.047	5.538SerGly: 5.538 ± 0.074	1.472SerHis: 1.472 ± 0.037	2.707SerIle: 2.707 ± 0.05	1.964SerLys: 1.964 ± 0.047	6.698SerLeu: 6.698 ± 0.086	1.535SerMet: 1.535 ± 0.039	1.85SerAsn: 1.85 ± 0.046	2.556SerPro: 2.556 ± 0.052	2.604SerGln: 2.604 ± 0.048	3.5SerArg: 3.5 ± 0.057	3.554SerSer: 3.554 ± 0.069	2.837SerThr: 2.837 ± 0.053	4.124SerVal: 4.124 ± 0.067	1.013SerTrp: 1.013 ± 0.03	1.566SerTyr: 1.566 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	4.955ThrAla: 4.955 ± 0.063	0.449ThrCys: 0.449 ± 0.019	2.508ThrAsp: 2.508 ± 0.046	2.263ThrGlu: 2.263 ± 0.047	1.909ThrPhe: 1.909 ± 0.037	4.238ThrGly: 4.238 ± 0.067	1.227ThrHis: 1.227 ± 0.031	2.475ThrIle: 2.475 ± 0.048	1.301ThrLys: 1.301 ± 0.037	7.776ThrLeu: 7.776 ± 0.086	1.16ThrMet: 1.16 ± 0.032	1.353ThrAsn: 1.353 ± 0.04	3.149ThrPro: 3.149 ± 0.06	2.282ThrGln: 2.282 ± 0.044	3.178ThrArg: 3.178 ± 0.054	2.777ThrSer: 2.777 ± 0.049	2.634ThrThr: 2.634 ± 0.056	3.737ThrVal: 3.737 ± 0.063	0.646ThrTrp: 0.646 ± 0.024	1.03ThrTyr: 1.03 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	7.322ValAla: 7.322 ± 0.079	0.732ValCys: 0.732 ± 0.025	3.677ValAsp: 3.677 ± 0.054	3.742ValGlu: 3.742 ± 0.064	2.361ValPhe: 2.361 ± 0.048	4.581ValGly: 4.581 ± 0.075	1.269ValHis: 1.269 ± 0.032	4.309ValIle: 4.309 ± 0.061	2.862ValLys: 2.862 ± 0.067	7.385ValLeu: 7.385 ± 0.099	2.256ValMet: 2.256 ± 0.047	2.718ValAsn: 2.718 ± 0.048	3.046ValPro: 3.046 ± 0.053	2.644ValGln: 2.644 ± 0.051	3.909ValArg: 3.909 ± 0.067	4.677ValSer: 4.677 ± 0.07	4.229ValThr: 4.229 ± 0.058	5.315ValVal: 5.315 ± 0.078	0.946ValTrp: 0.946 ± 0.027	1.582ValTyr: 1.582 ± 0.037	0.003ValXaa: 0.003 ± 0.002
Trp	0.997TrpAla: 0.997 ± 0.03	0.208TrpCys: 0.208 ± 0.014	0.614TrpAsp: 0.614 ± 0.025	0.499TrpGlu: 0.499 ± 0.022	0.655TrpPhe: 0.655 ± 0.025	0.818TrpGly: 0.818 ± 0.029	0.498TrpHis: 0.498 ± 0.022	0.715TrpIle: 0.715 ± 0.028	0.496TrpLys: 0.496 ± 0.021	2.363TrpLeu: 2.363 ± 0.053	0.412TrpMet: 0.412 ± 0.02	0.451TrpAsn: 0.451 ± 0.02	0.687TrpPro: 0.687 ± 0.027	1.478TrpGln: 1.478 ± 0.044	1.225TrpArg: 1.225 ± 0.037	0.857TrpSer: 0.857 ± 0.026	0.519TrpThr: 0.519 ± 0.022	0.898TrpVal: 0.898 ± 0.029	0.246TrpTrp: 0.246 ± 0.015	0.409TrpTyr: 0.409 ± 0.02	0.001TrpXaa: 0.001 ± 0.001
Tyr	2.322TyrAla: 2.322 ± 0.048	0.375TyrCys: 0.375 ± 0.018	1.522TyrAsp: 1.522 ± 0.036	1.051TyrGlu: 1.051 ± 0.032	1.007TyrPhe: 1.007 ± 0.03	2.129TyrGly: 2.129 ± 0.04	0.725TyrHis: 0.725 ± 0.025	1.267TyrIle: 1.267 ± 0.035	0.797TyrLys: 0.797 ± 0.034	2.892TyrLeu: 2.892 ± 0.051	0.58TyrMet: 0.58 ± 0.024	0.897TyrAsn: 0.897 ± 0.029	1.262TyrPro: 1.262 ± 0.034	1.664TyrGln: 1.664 ± 0.045	1.913TyrArg: 1.913 ± 0.046	1.551TyrSer: 1.551 ± 0.034	1.243TyrThr: 1.243 ± 0.034	1.672TyrVal: 1.672 ± 0.041	0.44TyrTrp: 0.44 ± 0.02	0.812TyrTyr: 0.812 ± 0.028	0.002TyrXaa: 0.002 ± 0.001
Xaa	0.003XaaAla: 0.003 ± 0.002	0.002XaaCys: 0.002 ± 0.001	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.001XaaHis: 0.001 ± 0.001	0.001XaaIle: 0.001 ± 0.001	0.003XaaLys: 0.003 ± 0.002	0.002XaaLeu: 0.002 ± 0.001	0.001XaaMet: 0.001 ± 0.001	0.003XaaAsn: 0.003 ± 0.002	0.001XaaPro: 0.001 ± 0.001	0.001XaaGln: 0.001 ± 0.001	0.003XaaArg: 0.003 ± 0.002	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.001	0.003XaaVal: 0.003 ± 0.002	0.002XaaTrp: 0.002 ± 0.001	0.002XaaTyr: 0.002 ± 0.001	0.005XaaXaa: 0.005 ± 0.003

Statistics based on 5007 proteins (1118627 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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