Amino acid dipepetide frequency for Halomicronema hongdechloris C2206

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.915AlaAla: 10.915 ± 0.133	0.965AlaCys: 0.965 ± 0.027	5.559AlaAsp: 5.559 ± 0.068	5.864AlaGlu: 5.864 ± 0.08	3.107AlaPhe: 3.107 ± 0.048	6.558AlaGly: 6.558 ± 0.072	1.863AlaHis: 1.863 ± 0.037	6.334AlaIle: 6.334 ± 0.067	2.795AlaLys: 2.795 ± 0.053	11.48AlaLeu: 11.48 ± 0.103	2.373AlaMet: 2.373 ± 0.04	2.925AlaAsn: 2.925 ± 0.052	4.202AlaPro: 4.202 ± 0.06	5.398AlaGln: 5.398 ± 0.068	4.805AlaArg: 4.805 ± 0.064	5.429AlaSer: 5.429 ± 0.059	5.737AlaThr: 5.737 ± 0.064	6.676AlaVal: 6.676 ± 0.071	1.504AlaTrp: 1.504 ± 0.038	2.769AlaTyr: 2.769 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.65CysAla: 0.65 ± 0.019	0.185CysCys: 0.185 ± 0.011	0.709CysAsp: 0.709 ± 0.019	0.463CysGlu: 0.463 ± 0.018	0.417CysPhe: 0.417 ± 0.018	0.766CysGly: 0.766 ± 0.022	0.369CysHis: 0.369 ± 0.016	0.465CysIle: 0.465 ± 0.019	0.223CysLys: 0.223 ± 0.012	1.345CysLeu: 1.345 ± 0.035	0.164CysMet: 0.164 ± 0.011	0.281CysAsn: 0.281 ± 0.016	0.641CysPro: 0.641 ± 0.021	0.677CysGln: 0.677 ± 0.021	0.811CysArg: 0.811 ± 0.025	0.606CysSer: 0.606 ± 0.02	0.399CysThr: 0.399 ± 0.016	0.51CysVal: 0.51 ± 0.017	0.167CysTrp: 0.167 ± 0.01	0.339CysTyr: 0.339 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.771AspAla: 4.771 ± 0.055	0.578AspCys: 0.578 ± 0.019	3.006AspAsp: 3.006 ± 0.067	2.949AspGlu: 2.949 ± 0.057	2.216AspPhe: 2.216 ± 0.046	3.85AspGly: 3.85 ± 0.068	1.25AspHis: 1.25 ± 0.029	3.114AspIle: 3.114 ± 0.05	1.242AspLys: 1.242 ± 0.034	6.515AspLeu: 6.515 ± 0.086	0.949AspMet: 0.949 ± 0.027	1.59AspAsn: 1.59 ± 0.035	3.382AspPro: 3.382 ± 0.051	2.715AspGln: 2.715 ± 0.044	3.819AspArg: 3.819 ± 0.052	2.979AspSer: 2.979 ± 0.046	2.932AspThr: 2.932 ± 0.048	3.224AspVal: 3.224 ± 0.049	1.117AspTrp: 1.117 ± 0.024	1.976AspTyr: 1.976 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.735GluAla: 6.735 ± 0.08	0.382GluCys: 0.382 ± 0.019	2.758GluAsp: 2.758 ± 0.051	3.077GluGlu: 3.077 ± 0.054	1.968GluPhe: 1.968 ± 0.037	3.153GluGly: 3.153 ± 0.054	1.223GluHis: 1.223 ± 0.029	3.128GluIle: 3.128 ± 0.049	1.752GluLys: 1.752 ± 0.046	6.236GluLeu: 6.236 ± 0.062	1.244GluMet: 1.244 ± 0.032	1.528GluAsn: 1.528 ± 0.036	2.665GluPro: 2.665 ± 0.049	3.636GluGln: 3.636 ± 0.059	3.927GluArg: 3.927 ± 0.058	2.914GluSer: 2.914 ± 0.046	3.602GluThr: 3.602 ± 0.049	3.917GluVal: 3.917 ± 0.055	0.785GluTrp: 0.785 ± 0.023	1.369GluTyr: 1.369 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	2.831PheAla: 2.831 ± 0.044	0.495PheCys: 0.495 ± 0.019	2.198PheAsp: 2.198 ± 0.042	2.024PheGlu: 2.024 ± 0.041	1.385PhePhe: 1.385 ± 0.033	2.771PheGly: 2.771 ± 0.049	0.815PheHis: 0.815 ± 0.027	1.852PheIle: 1.852 ± 0.042	0.969PheLys: 0.969 ± 0.028	3.689PheLeu: 3.689 ± 0.06	0.638PheMet: 0.638 ± 0.022	1.189PheAsn: 1.189 ± 0.028	1.771PhePro: 1.771 ± 0.039	1.84PheGln: 1.84 ± 0.035	2.057PheArg: 2.057 ± 0.036	2.485PheSer: 2.485 ± 0.046	1.969PheThr: 1.969 ± 0.035	2.111PheVal: 2.111 ± 0.035	0.671PheTrp: 0.671 ± 0.02	1.132PheTyr: 1.132 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	5.553GlyAla: 5.553 ± 0.081	0.871GlyCys: 0.871 ± 0.026	3.996GlyAsp: 3.996 ± 0.061	3.799GlyGlu: 3.799 ± 0.053	2.884GlyPhe: 2.884 ± 0.046	5.025GlyGly: 5.025 ± 0.073	1.821GlyHis: 1.821 ± 0.036	4.575GlyIle: 4.575 ± 0.06	2.433GlyLys: 2.433 ± 0.044	8.266GlyLeu: 8.266 ± 0.087	1.572GlyMet: 1.572 ± 0.036	2.454GlyAsn: 2.454 ± 0.05	2.529GlyPro: 2.529 ± 0.041	4.094GlyGln: 4.094 ± 0.063	4.427GlyArg: 4.427 ± 0.055	4.182GlySer: 4.182 ± 0.059	3.87GlyThr: 3.87 ± 0.06	4.864GlyVal: 4.864 ± 0.071	1.401GlyTrp: 1.401 ± 0.027	2.395GlyTyr: 2.395 ± 0.038	0.0GlyXaa: 0.0 ± 0.0
His	1.481HisAla: 1.481 ± 0.035	0.349HisCys: 0.349 ± 0.014	1.066HisAsp: 1.066 ± 0.028	0.927HisGlu: 0.927 ± 0.026	0.845HisPhe: 0.845 ± 0.027	1.589HisGly: 1.589 ± 0.031	0.939HisHis: 0.939 ± 0.03	1.115HisIle: 1.115 ± 0.028	0.499HisLys: 0.499 ± 0.019	3.049HisLeu: 3.049 ± 0.05	0.347HisMet: 0.347 ± 0.016	0.596HisAsn: 0.596 ± 0.018	1.88HisPro: 1.88 ± 0.037	1.562HisGln: 1.562 ± 0.034	1.854HisArg: 1.854 ± 0.037	1.249HisSer: 1.249 ± 0.029	1.019HisThr: 1.019 ± 0.027	1.072HisVal: 1.072 ± 0.034	0.572HisTrp: 0.572 ± 0.022	0.91HisTyr: 0.91 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.084IleAla: 6.084 ± 0.073	0.625IleCys: 0.625 ± 0.021	3.369IleAsp: 3.369 ± 0.051	3.386IleGlu: 3.386 ± 0.057	1.788IlePhe: 1.788 ± 0.04	4.006IleGly: 4.006 ± 0.06	1.239IleHis: 1.239 ± 0.026	2.356IleIle: 2.356 ± 0.041	1.463IleLys: 1.463 ± 0.034	5.47IleLeu: 5.47 ± 0.066	0.689IleMet: 0.689 ± 0.024	1.697IleAsn: 1.697 ± 0.035	3.004IlePro: 3.004 ± 0.048	2.578IleGln: 2.578 ± 0.04	3.175IleArg: 3.175 ± 0.046	3.231IleSer: 3.231 ± 0.05	3.081IleThr: 3.081 ± 0.045	3.437IleVal: 3.437 ± 0.051	0.79IleTrp: 0.79 ± 0.025	1.497IleTyr: 1.497 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	2.972LysAla: 2.972 ± 0.054	0.169LysCys: 0.169 ± 0.011	1.338LysAsp: 1.338 ± 0.034	1.381LysGlu: 1.381 ± 0.037	0.865LysPhe: 0.865 ± 0.027	1.803LysGly: 1.803 ± 0.038	0.615LysHis: 0.615 ± 0.024	1.481LysIle: 1.481 ± 0.036	0.957LysLys: 0.957 ± 0.028	3.137LysLeu: 3.137 ± 0.054	0.512LysMet: 0.512 ± 0.021	0.754LysAsn: 0.754 ± 0.027	1.625LysPro: 1.625 ± 0.037	1.763LysGln: 1.763 ± 0.041	2.0LysArg: 2.0 ± 0.039	1.672LysSer: 1.672 ± 0.039	1.88LysThr: 1.88 ± 0.033	1.869LysVal: 1.869 ± 0.042	0.294LysTrp: 0.294 ± 0.013	0.749LysTyr: 0.749 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	12.067LeuAla: 12.067 ± 0.11	1.152LeuCys: 1.152 ± 0.026	6.035LeuAsp: 6.035 ± 0.079	7.029LeuGlu: 7.029 ± 0.076	3.585LeuPhe: 3.585 ± 0.055	8.696LeuGly: 8.696 ± 0.098	2.245LeuHis: 2.245 ± 0.038	5.66LeuIle: 5.66 ± 0.073	3.892LeuLys: 3.892 ± 0.056	12.331LeuLeu: 12.331 ± 0.118	2.461LeuMet: 2.461 ± 0.045	3.643LeuAsn: 3.643 ± 0.057	6.585LeuPro: 6.585 ± 0.086	6.706LeuGln: 6.706 ± 0.082	7.198LeuArg: 7.198 ± 0.071	7.775LeuSer: 7.775 ± 0.096	6.856LeuThr: 6.856 ± 0.065	7.873LeuVal: 7.873 ± 0.075	1.859LeuTrp: 1.859 ± 0.04	2.955LeuTyr: 2.955 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.854MetAla: 2.854 ± 0.044	0.108MetCys: 0.108 ± 0.008	0.891MetAsp: 0.891 ± 0.025	0.945MetGlu: 0.945 ± 0.024	0.435MetPhe: 0.435 ± 0.019	1.581MetGly: 1.581 ± 0.036	0.339MetHis: 0.339 ± 0.014	0.866MetIle: 0.866 ± 0.028	0.634MetLys: 0.634 ± 0.023	1.845MetLeu: 1.845 ± 0.032	0.419MetMet: 0.419 ± 0.016	0.567MetAsn: 0.567 ± 0.016	1.186MetPro: 1.186 ± 0.03	0.953MetGln: 0.953 ± 0.024	1.093MetArg: 1.093 ± 0.03	1.13MetSer: 1.13 ± 0.032	1.508MetThr: 1.508 ± 0.032	1.728MetVal: 1.728 ± 0.036	0.136MetTrp: 0.136 ± 0.011	0.324MetTyr: 0.324 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.373AsnAla: 2.373 ± 0.041	0.311AsnCys: 0.311 ± 0.015	1.371AsnAsp: 1.371 ± 0.031	1.187AsnGlu: 1.187 ± 0.03	1.124AsnPhe: 1.124 ± 0.029	2.121AsnGly: 2.121 ± 0.044	0.756AsnHis: 0.756 ± 0.022	1.402AsnIle: 1.402 ± 0.032	0.652AsnLys: 0.652 ± 0.024	3.827AsnLeu: 3.827 ± 0.064	0.398AsnMet: 0.398 ± 0.017	0.92AsnAsn: 0.92 ± 0.031	2.27AsnPro: 2.27 ± 0.039	1.909AsnGln: 1.909 ± 0.036	2.216AsnArg: 2.216 ± 0.038	1.651AsnSer: 1.651 ± 0.034	1.504AsnThr: 1.504 ± 0.035	1.649AsnVal: 1.649 ± 0.032	0.565AsnTrp: 0.565 ± 0.019	0.896AsnTyr: 0.896 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.039ProAla: 5.039 ± 0.081	0.475ProCys: 0.475 ± 0.017	3.835ProAsp: 3.835 ± 0.057	4.177ProGlu: 4.177 ± 0.054	1.796ProPhe: 1.796 ± 0.035	3.932ProGly: 3.932 ± 0.061	1.239ProHis: 1.239 ± 0.028	2.673ProIle: 2.673 ± 0.04	1.514ProLys: 1.514 ± 0.034	6.016ProLeu: 6.016 ± 0.073	1.16ProMet: 1.16 ± 0.026	1.649ProAsn: 1.649 ± 0.036	3.36ProPro: 3.36 ± 0.054	3.087ProGln: 3.087 ± 0.046	2.647ProArg: 2.647 ± 0.044	3.558ProSer: 3.558 ± 0.053	3.243ProThr: 3.243 ± 0.052	3.724ProVal: 3.724 ± 0.056	0.918ProTrp: 0.918 ± 0.023	1.487ProTyr: 1.487 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	7.159GlnAla: 7.159 ± 0.096	0.42GlnCys: 0.42 ± 0.016	2.637GlnAsp: 2.637 ± 0.046	3.141GlnGlu: 3.141 ± 0.049	1.778GlnPhe: 1.778 ± 0.032	4.366GlnGly: 4.366 ± 0.054	1.303GlnHis: 1.303 ± 0.037	2.918GlnIle: 2.918 ± 0.044	1.356GlnLys: 1.356 ± 0.033	6.64GlnLeu: 6.64 ± 0.08	1.06GlnMet: 1.06 ± 0.026	1.125GlnAsn: 1.125 ± 0.029	3.357GlnPro: 3.357 ± 0.048	4.679GlnGln: 4.679 ± 0.092	4.622GlnArg: 4.622 ± 0.059	3.014GlnSer: 3.014 ± 0.053	3.175GlnThr: 3.175 ± 0.051	4.566GlnVal: 4.566 ± 0.058	0.925GlnTrp: 0.925 ± 0.025	1.224GlnTyr: 1.224 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	4.682ArgAla: 4.682 ± 0.061	0.748ArgCys: 0.748 ± 0.021	3.174ArgAsp: 3.174 ± 0.046	3.2ArgGlu: 3.2 ± 0.048	2.503ArgPhe: 2.503 ± 0.045	3.712ArgGly: 3.712 ± 0.055	1.779ArgHis: 1.779 ± 0.035	3.286ArgIle: 3.286 ± 0.043	1.657ArgLys: 1.657 ± 0.041	8.345ArgLeu: 8.345 ± 0.08	1.116ArgMet: 1.116 ± 0.027	1.672ArgAsn: 1.672 ± 0.032	3.281ArgPro: 3.281 ± 0.05	5.185ArgGln: 5.185 ± 0.064	4.967ArgArg: 4.967 ± 0.072	3.803ArgSer: 3.803 ± 0.048	2.851ArgThr: 2.851 ± 0.05	4.193ArgVal: 4.193 ± 0.053	1.333ArgTrp: 1.333 ± 0.03	2.267ArgTyr: 2.267 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.844SerAla: 4.844 ± 0.066	0.557SerCys: 0.557 ± 0.02	3.213SerAsp: 3.213 ± 0.049	3.19SerGlu: 3.19 ± 0.052	2.136SerPhe: 2.136 ± 0.043	4.613SerGly: 4.613 ± 0.064	1.525SerHis: 1.525 ± 0.033	2.848SerIle: 2.848 ± 0.051	1.502SerLys: 1.502 ± 0.037	7.525SerLeu: 7.525 ± 0.076	1.185SerMet: 1.185 ± 0.028	1.749SerAsn: 1.749 ± 0.035	4.038SerPro: 4.038 ± 0.056	3.607SerGln: 3.607 ± 0.052	3.732SerArg: 3.732 ± 0.051	3.974SerSer: 3.974 ± 0.063	3.227SerThr: 3.227 ± 0.049	3.676SerVal: 3.676 ± 0.049	0.971SerTrp: 0.971 ± 0.027	1.561SerTyr: 1.561 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.925ThrAla: 5.925 ± 0.067	0.536ThrCys: 0.536 ± 0.02	2.845ThrAsp: 2.845 ± 0.046	2.87ThrGlu: 2.87 ± 0.052	1.897ThrPhe: 1.897 ± 0.036	4.047ThrGly: 4.047 ± 0.059	1.216ThrHis: 1.216 ± 0.028	3.023ThrIle: 3.023 ± 0.046	1.227ThrLys: 1.227 ± 0.031	7.373ThrLeu: 7.373 ± 0.091	0.979ThrMet: 0.979 ± 0.026	1.449ThrAsn: 1.449 ± 0.033	3.808ThrPro: 3.808 ± 0.06	2.713ThrGln: 2.713 ± 0.044	2.867ThrArg: 2.867 ± 0.043	3.154ThrSer: 3.154 ± 0.049	3.374ThrThr: 3.374 ± 0.054	4.324ThrVal: 4.324 ± 0.055	0.926ThrTrp: 0.926 ± 0.026	1.703ThrTyr: 1.703 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	6.896ValAla: 6.896 ± 0.075	0.706ValCys: 0.706 ± 0.02	3.852ValAsp: 3.852 ± 0.051	4.054ValGlu: 4.054 ± 0.052	2.388ValPhe: 2.388 ± 0.042	4.772ValGly: 4.772 ± 0.057	1.204ValHis: 1.204 ± 0.025	3.825ValIle: 3.825 ± 0.053	2.03ValLys: 2.03 ± 0.036	7.522ValLeu: 7.522 ± 0.074	1.517ValMet: 1.517 ± 0.031	2.147ValAsn: 2.147 ± 0.038	3.553ValPro: 3.553 ± 0.051	3.017ValGln: 3.017 ± 0.04	3.808ValArg: 3.808 ± 0.049	4.166ValSer: 4.166 ± 0.062	4.008ValThr: 4.008 ± 0.048	5.196ValVal: 5.196 ± 0.071	0.949ValTrp: 0.949 ± 0.028	1.764ValTyr: 1.764 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.258TrpAla: 1.258 ± 0.03	0.173TrpCys: 0.173 ± 0.009	0.714TrpAsp: 0.714 ± 0.026	0.738TrpGlu: 0.738 ± 0.026	0.639TrpPhe: 0.639 ± 0.022	1.19TrpGly: 1.19 ± 0.032	0.45TrpHis: 0.45 ± 0.019	0.83TrpIle: 0.83 ± 0.024	0.407TrpLys: 0.407 ± 0.016	2.521TrpLeu: 2.521 ± 0.046	0.386TrpMet: 0.386 ± 0.015	0.44TrpAsn: 0.44 ± 0.018	0.768TrpPro: 0.768 ± 0.024	1.606TrpGln: 1.606 ± 0.034	1.163TrpArg: 1.163 ± 0.03	0.999TrpSer: 0.999 ± 0.028	0.685TrpThr: 0.685 ± 0.023	1.103TrpVal: 1.103 ± 0.024	0.316TrpTrp: 0.316 ± 0.014	0.409TrpTyr: 0.409 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.169TyrAla: 2.169 ± 0.038	0.383TyrCys: 0.383 ± 0.015	1.608TyrAsp: 1.608 ± 0.035	1.596TyrGlu: 1.596 ± 0.035	1.136TyrPhe: 1.136 ± 0.031	2.461TyrGly: 2.461 ± 0.043	0.73TyrHis: 0.73 ± 0.023	1.212TyrIle: 1.212 ± 0.03	0.634TyrLys: 0.634 ± 0.026	3.472TyrLeu: 3.472 ± 0.049	0.372TyrMet: 0.372 ± 0.016	0.728TyrAsn: 0.728 ± 0.025	1.624TyrPro: 1.624 ± 0.032	1.738TyrGln: 1.738 ± 0.035	2.57TyrArg: 2.57 ± 0.042	1.7TyrSer: 1.7 ± 0.038	1.335TyrThr: 1.335 ± 0.033	1.662TyrVal: 1.662 ± 0.03	0.598TyrTrp: 0.598 ± 0.021	0.936TyrTyr: 0.936 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5211 proteins (1532136 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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