Amino acid dipepetide frequency for Apis mellifera associated microvirus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.831AlaAla: 9.831 ± 2.557
1.404AlaCys: 1.404 ± 1.398
6.32AlaAsp: 6.32 ± 3.021
6.32AlaGlu: 6.32 ± 2.315
5.618AlaPhe: 5.618 ± 2.364
4.916AlaGly: 4.916 ± 2.51
2.107AlaHis: 2.107 ± 0.611
2.107AlaIle: 2.107 ± 0.814
0.702AlaLys: 0.702 ± 0.731
9.831AlaLeu: 9.831 ± 2.581
3.511AlaMet: 3.511 ± 1.112
2.107AlaAsn: 2.107 ± 1.515
4.213AlaPro: 4.213 ± 3.501
4.916AlaGln: 4.916 ± 1.87
8.427AlaArg: 8.427 ± 1.554
5.618AlaSer: 5.618 ± 3.256
8.427AlaThr: 8.427 ± 2.453
7.725AlaVal: 7.725 ± 2.926
0.0AlaTrp: 0.0 ± 0.0
4.916AlaTyr: 4.916 ± 1.922
0.0AlaXaa: 0.0 ± 0.0
Cys
2.809CysAla: 2.809 ± 0.974
0.0CysCys: 0.0 ± 0.0
0.702CysAsp: 0.702 ± 0.68
0.0CysGlu: 0.0 ± 0.0
0.702CysPhe: 0.702 ± 0.907
2.107CysGly: 2.107 ± 2.005
0.702CysHis: 0.702 ± 0.907
0.702CysIle: 0.702 ± 0.907
0.0CysLys: 0.0 ± 0.0
1.404CysLeu: 1.404 ± 0.903
2.809CysMet: 2.809 ± 1.574
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.702CysArg: 0.702 ± 0.668
0.702CysSer: 0.702 ± 0.907
0.702CysThr: 0.702 ± 0.668
1.404CysVal: 1.404 ± 1.815
0.0CysTrp: 0.0 ± 0.0
1.404CysTyr: 1.404 ± 1.068
0.0CysXaa: 0.0 ± 0.0
Asp
7.725AspAla: 7.725 ± 2.478
1.404AspCys: 1.404 ± 0.903
1.404AspAsp: 1.404 ± 1.068
2.107AspGlu: 2.107 ± 1.35
2.107AspPhe: 2.107 ± 1.157
3.511AspGly: 3.511 ± 1.28
1.404AspHis: 1.404 ± 0.592
1.404AspIle: 1.404 ± 0.914
2.107AspLys: 2.107 ± 1.191
2.809AspLeu: 2.809 ± 0.931
1.404AspMet: 1.404 ± 1.217
4.916AspAsn: 4.916 ± 1.644
2.809AspPro: 2.809 ± 0.688
1.404AspGln: 1.404 ± 0.86
2.809AspArg: 2.809 ± 0.66
4.916AspSer: 4.916 ± 2.479
2.809AspThr: 2.809 ± 0.94
3.511AspVal: 3.511 ± 2.049
0.702AspTrp: 0.702 ± 0.668
3.511AspTyr: 3.511 ± 1.968
0.0AspXaa: 0.0 ± 0.0
Glu
6.32GluAla: 6.32 ± 2.596
0.702GluCys: 0.702 ± 0.68
2.107GluAsp: 2.107 ± 1.586
1.404GluGlu: 1.404 ± 1.463
3.511GluPhe: 3.511 ± 2.309
3.511GluGly: 3.511 ± 2.279
0.702GluHis: 0.702 ± 0.505
2.809GluIle: 2.809 ± 1.531
2.107GluLys: 2.107 ± 1.031
0.702GluLeu: 0.702 ± 0.668
0.0GluMet: 0.0 ± 0.0
2.107GluAsn: 2.107 ± 1.271
3.511GluPro: 3.511 ± 2.663
1.404GluGln: 1.404 ± 1.01
5.618GluArg: 5.618 ± 2.311
0.0GluSer: 0.0 ± 0.0
1.404GluThr: 1.404 ± 1.337
2.809GluVal: 2.809 ± 1.574
2.107GluTrp: 2.107 ± 0.783
2.107GluTyr: 2.107 ± 0.874
0.0GluXaa: 0.0 ± 0.0
Phe
1.404PheAla: 1.404 ± 1.361
1.404PheCys: 1.404 ± 1.068
6.32PheAsp: 6.32 ± 1.917
2.107PheGlu: 2.107 ± 1.283
4.213PhePhe: 4.213 ± 1.912
4.213PheGly: 4.213 ± 1.6
0.702PheHis: 0.702 ± 0.731
1.404PheIle: 1.404 ± 0.663
2.107PheLys: 2.107 ± 0.814
0.702PheLeu: 0.702 ± 0.668
4.916PheMet: 4.916 ± 1.359
2.809PheAsn: 2.809 ± 1.325
0.0PhePro: 0.0 ± 0.0
2.809PheGln: 2.809 ± 1.058
2.809PheArg: 2.809 ± 1.806
2.809PheSer: 2.809 ± 1.299
3.511PheThr: 3.511 ± 1.883
2.809PheVal: 2.809 ± 1.296
0.0PheTrp: 0.0 ± 0.0
1.404PheTyr: 1.404 ± 1.337
0.0PheXaa: 0.0 ± 0.0
Gly
5.618GlyAla: 5.618 ± 2.099
1.404GlyCys: 1.404 ± 1.337
6.32GlyAsp: 6.32 ± 2.866
2.809GlyGlu: 2.809 ± 0.974
1.404GlyPhe: 1.404 ± 0.592
7.022GlyGly: 7.022 ± 1.158
0.702GlyHis: 0.702 ± 0.505
2.809GlyIle: 2.809 ± 1.096
2.809GlyLys: 2.809 ± 1.299
9.129GlyLeu: 9.129 ± 1.885
0.702GlyMet: 0.702 ± 0.875
2.107GlyAsn: 2.107 ± 0.889
3.511GlyPro: 3.511 ± 0.955
2.809GlyGln: 2.809 ± 1.806
2.809GlyArg: 2.809 ± 1.242
7.725GlySer: 7.725 ± 2.312
4.916GlyThr: 4.916 ± 2.237
7.725GlyVal: 7.725 ± 1.41
0.702GlyTrp: 0.702 ± 0.505
2.107GlyTyr: 2.107 ± 1.515
0.0GlyXaa: 0.0 ± 0.0
His
1.404HisAla: 1.404 ± 1.068
0.702HisCys: 0.702 ± 0.907
0.702HisAsp: 0.702 ± 0.505
1.404HisGlu: 1.404 ± 0.923
2.107HisPhe: 2.107 ± 1.515
1.404HisGly: 1.404 ± 1.01
0.0HisHis: 0.0 ± 0.0
2.107HisIle: 2.107 ± 0.874
0.0HisLys: 0.0 ± 0.0
0.702HisLeu: 0.702 ± 0.505
0.0HisMet: 0.0 ± 0.0
0.702HisAsn: 0.702 ± 0.668
0.702HisPro: 0.702 ± 0.505
0.0HisGln: 0.0 ± 0.0
2.107HisArg: 2.107 ± 0.874
0.702HisSer: 0.702 ± 0.505
0.702HisThr: 0.702 ± 0.731
1.404HisVal: 1.404 ± 0.914
0.0HisTrp: 0.0 ± 0.0
2.809HisTyr: 2.809 ± 1.613
0.0HisXaa: 0.0 ± 0.0
Ile
3.511IleAla: 3.511 ± 0.729
1.404IleCys: 1.404 ± 1.815
2.809IleAsp: 2.809 ± 1.03
0.702IleGlu: 0.702 ± 0.731
0.702IlePhe: 0.702 ± 0.731
3.511IleGly: 3.511 ± 0.955
0.0IleHis: 0.0 ± 0.0
0.702IleIle: 0.702 ± 0.731
0.0IleLys: 0.0 ± 0.0
4.916IleLeu: 4.916 ± 2.812
0.0IleMet: 0.0 ± 0.0
3.511IleAsn: 3.511 ± 1.389
3.511IlePro: 3.511 ± 1.149
0.0IleGln: 0.0 ± 0.0
1.404IleArg: 1.404 ± 0.906
1.404IleSer: 1.404 ± 0.86
0.0IleThr: 0.0 ± 0.0
2.809IleVal: 2.809 ± 0.66
1.404IleTrp: 1.404 ± 1.01
1.404IleTyr: 1.404 ± 1.01
0.0IleXaa: 0.0 ± 0.0
Lys
2.107LysAla: 2.107 ± 1.263
0.702LysCys: 0.702 ± 0.505
0.702LysAsp: 0.702 ± 0.731
3.511LysGlu: 3.511 ± 2.448
3.511LysPhe: 3.511 ± 1.115
4.916LysGly: 4.916 ± 0.918
0.702LysHis: 0.702 ± 0.903
0.702LysIle: 0.702 ± 0.505
4.213LysLys: 4.213 ± 2.464
1.404LysLeu: 1.404 ± 0.758
0.702LysMet: 0.702 ± 0.68
1.404LysAsn: 1.404 ± 1.463
0.702LysPro: 0.702 ± 0.505
0.702LysGln: 0.702 ± 0.668
4.213LysArg: 4.213 ± 2.353
3.511LysSer: 3.511 ± 2.202
1.404LysThr: 1.404 ± 0.663
2.809LysVal: 2.809 ± 1.071
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.831LeuAla: 9.831 ± 3.237
0.702LeuCys: 0.702 ± 0.668
4.213LeuAsp: 4.213 ± 1.342
2.809LeuGlu: 2.809 ± 1.304
0.702LeuPhe: 0.702 ± 0.907
5.618LeuGly: 5.618 ± 0.988
0.702LeuHis: 0.702 ± 0.505
7.022LeuIle: 7.022 ± 2.42
3.511LeuLys: 3.511 ± 1.712
5.618LeuLeu: 5.618 ± 1.717
2.809LeuMet: 2.809 ± 1.451
7.022LeuAsn: 7.022 ± 2.008
5.618LeuPro: 5.618 ± 1.574
2.107LeuGln: 2.107 ± 1.094
6.32LeuArg: 6.32 ± 2.024
6.32LeuSer: 6.32 ± 1.226
4.213LeuThr: 4.213 ± 1.334
3.511LeuVal: 3.511 ± 0.729
1.404LeuTrp: 1.404 ± 0.592
2.809LeuTyr: 2.809 ± 1.183
0.0LeuXaa: 0.0 ± 0.0
Met
1.404MetAla: 1.404 ± 1.217
0.702MetCys: 0.702 ± 0.68
4.213MetAsp: 4.213 ± 1.835
0.0MetGlu: 0.0 ± 0.0
0.702MetPhe: 0.702 ± 0.505
2.107MetGly: 2.107 ± 1.515
1.404MetHis: 1.404 ± 1.337
0.0MetIle: 0.0 ± 0.0
2.809MetLys: 2.809 ± 1.096
3.511MetLeu: 3.511 ± 0.878
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.404MetPro: 1.404 ± 0.758
0.0MetGln: 0.0 ± 0.0
3.511MetArg: 3.511 ± 1.616
5.618MetSer: 5.618 ± 1.134
1.404MetThr: 1.404 ± 1.068
1.404MetVal: 1.404 ± 1.01
0.0MetTrp: 0.0 ± 0.0
3.511MetTyr: 3.511 ± 1.905
0.0MetXaa: 0.0 ± 0.0
Asn
4.916AsnAla: 4.916 ± 2.357
0.0AsnCys: 0.0 ± 0.0
3.511AsnAsp: 3.511 ± 1.209
0.702AsnGlu: 0.702 ± 0.505
2.107AsnPhe: 2.107 ± 1.079
2.107AsnGly: 2.107 ± 1.094
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
0.702AsnLys: 0.702 ± 0.505
7.725AsnLeu: 7.725 ± 1.893
2.809AsnMet: 2.809 ± 1.96
0.702AsnAsn: 0.702 ± 0.907
4.213AsnPro: 4.213 ± 1.564
2.809AsnGln: 2.809 ± 0.931
2.107AsnArg: 2.107 ± 0.923
4.916AsnSer: 4.916 ± 2.164
3.511AsnThr: 3.511 ± 0.723
4.213AsnVal: 4.213 ± 1.078
0.0AsnTrp: 0.0 ± 0.0
1.404AsnTyr: 1.404 ± 0.758
0.0AsnXaa: 0.0 ± 0.0
Pro
6.32ProAla: 6.32 ± 1.475
0.702ProCys: 0.702 ± 0.668
2.809ProAsp: 2.809 ± 1.526
3.511ProGlu: 3.511 ± 1.559
2.107ProPhe: 2.107 ± 0.889
4.213ProGly: 4.213 ± 1.671
2.107ProHis: 2.107 ± 0.814
3.511ProIle: 3.511 ± 1.004
0.0ProLys: 0.0 ± 0.0
4.916ProLeu: 4.916 ± 1.327
2.107ProMet: 2.107 ± 1.094
0.702ProAsn: 0.702 ± 0.505
3.511ProPro: 3.511 ± 1.835
2.809ProGln: 2.809 ± 1.531
4.916ProArg: 4.916 ± 1.959
4.213ProSer: 4.213 ± 1.917
1.404ProThr: 1.404 ± 0.86
4.213ProVal: 4.213 ± 1.917
0.702ProTrp: 0.702 ± 0.505
0.702ProTyr: 0.702 ± 0.668
0.0ProXaa: 0.0 ± 0.0
Gln
1.404GlnAla: 1.404 ± 0.663
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.809GlnGlu: 2.809 ± 1.296
2.107GlnPhe: 2.107 ± 1.898
3.511GlnGly: 3.511 ± 1.993
2.107GlnHis: 2.107 ± 0.772
0.0GlnIle: 0.0 ± 0.0
3.511GlnLys: 3.511 ± 0.627
2.107GlnLeu: 2.107 ± 1.301
1.404GlnMet: 1.404 ± 0.592
3.511GlnAsn: 3.511 ± 1.414
2.107GlnPro: 2.107 ± 1.022
2.107GlnGln: 2.107 ± 1.301
3.511GlnArg: 3.511 ± 0.999
2.107GlnSer: 2.107 ± 1.515
1.404GlnThr: 1.404 ± 0.663
2.107GlnVal: 2.107 ± 1.515
0.702GlnTrp: 0.702 ± 0.668
0.702GlnTyr: 0.702 ± 0.903
0.0GlnXaa: 0.0 ± 0.0
Arg
7.022ArgAla: 7.022 ± 1.576
2.107ArgCys: 2.107 ± 1.505
2.107ArgAsp: 2.107 ± 0.923
1.404ArgGlu: 1.404 ± 1.463
4.213ArgPhe: 4.213 ± 2.353
2.809ArgGly: 2.809 ± 1.058
1.404ArgHis: 1.404 ± 0.592
0.702ArgIle: 0.702 ± 0.668
4.916ArgLys: 4.916 ± 2.293
8.427ArgLeu: 8.427 ± 2.188
2.809ArgMet: 2.809 ± 0.66
1.404ArgAsn: 1.404 ± 1.463
4.213ArgPro: 4.213 ± 1.713
4.213ArgGln: 4.213 ± 1.288
6.32ArgArg: 6.32 ± 2.725
7.022ArgSer: 7.022 ± 1.289
2.107ArgThr: 2.107 ± 1.283
3.511ArgVal: 3.511 ± 0.729
0.0ArgTrp: 0.0 ± 0.0
2.809ArgTyr: 2.809 ± 1.299
0.0ArgXaa: 0.0 ± 0.0
Ser
12.64SerAla: 12.64 ± 4.643
2.107SerCys: 2.107 ± 1.157
2.107SerAsp: 2.107 ± 0.772
2.809SerGlu: 2.809 ± 1.096
4.916SerPhe: 4.916 ± 0.865
3.511SerGly: 3.511 ± 1.905
2.809SerHis: 2.809 ± 1.526
2.809SerIle: 2.809 ± 2.883
1.404SerLys: 1.404 ± 0.906
7.022SerLeu: 7.022 ± 2.917
0.702SerMet: 0.702 ± 0.505
4.916SerAsn: 4.916 ± 1.327
3.511SerPro: 3.511 ± 1.345
0.702SerGln: 0.702 ± 0.731
3.511SerArg: 3.511 ± 1.835
11.938SerSer: 11.938 ± 3.975
3.511SerThr: 3.511 ± 1.792
6.32SerVal: 6.32 ± 2.355
0.702SerTrp: 0.702 ± 0.668
1.404SerTyr: 1.404 ± 0.86
0.0SerXaa: 0.0 ± 0.0
Thr
4.916ThrAla: 4.916 ± 1.736
0.0ThrCys: 0.0 ± 0.0
0.702ThrAsp: 0.702 ± 0.505
3.511ThrGlu: 3.511 ± 1.268
2.107ThrPhe: 2.107 ± 0.874
9.831ThrGly: 9.831 ± 1.463
0.0ThrHis: 0.0 ± 0.0
2.809ThrIle: 2.809 ± 1.435
1.404ThrLys: 1.404 ± 0.903
2.107ThrLeu: 2.107 ± 1.157
1.404ThrMet: 1.404 ± 0.592
1.404ThrAsn: 1.404 ± 0.663
2.809ThrPro: 2.809 ± 2.02
0.702ThrGln: 0.702 ± 0.505
4.213ThrArg: 4.213 ± 1.346
4.213ThrSer: 4.213 ± 2.25
0.0ThrThr: 0.0 ± 0.0
2.809ThrVal: 2.809 ± 0.931
0.702ThrTrp: 0.702 ± 0.505
0.702ThrTyr: 0.702 ± 0.668
0.0ThrXaa: 0.0 ± 0.0
Val
5.618ValAla: 5.618 ± 0.978
1.404ValCys: 1.404 ± 1.815
4.213ValAsp: 4.213 ± 1.17
4.213ValGlu: 4.213 ± 1.288
4.213ValPhe: 4.213 ± 1.777
4.213ValGly: 4.213 ± 1.405
0.0ValHis: 0.0 ± 0.0
2.107ValIle: 2.107 ± 0.783
2.809ValLys: 2.809 ± 1.216
4.916ValLeu: 4.916 ± 1.547
2.107ValMet: 2.107 ± 0.783
7.725ValAsn: 7.725 ± 2.051
4.916ValPro: 4.916 ± 2.18
4.916ValGln: 4.916 ± 1.635
2.809ValArg: 2.809 ± 0.688
4.213ValSer: 4.213 ± 1.13
4.213ValThr: 4.213 ± 1.183
5.618ValVal: 5.618 ± 1.215
0.0ValTrp: 0.0 ± 0.0
0.702ValTyr: 0.702 ± 0.505
0.0ValXaa: 0.0 ± 0.0
Trp
1.404TrpAla: 1.404 ± 0.592
0.0TrpCys: 0.0 ± 0.0
0.702TrpAsp: 0.702 ± 0.668
0.702TrpGlu: 0.702 ± 0.668
0.702TrpPhe: 0.702 ± 0.505
0.702TrpGly: 0.702 ± 0.68
1.404TrpHis: 1.404 ± 1.01
0.0TrpIle: 0.0 ± 0.0
0.702TrpLys: 0.702 ± 0.505
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.702TrpAsn: 0.702 ± 0.505
2.107TrpPro: 2.107 ± 0.874
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.702TrpTyr: 0.702 ± 0.668
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.809TyrAla: 2.809 ± 1.531
0.0TyrCys: 0.0 ± 0.0
2.809TyrAsp: 2.809 ± 2.115
2.107TyrGlu: 2.107 ± 0.783
0.702TyrPhe: 0.702 ± 0.505
2.107TyrGly: 2.107 ± 2.005
0.702TyrHis: 0.702 ± 0.668
0.0TyrIle: 0.0 ± 0.0
2.107TyrLys: 2.107 ± 1.157
4.916TyrLeu: 4.916 ± 1.873
2.809TyrMet: 2.809 ± 1.068
0.702TyrAsn: 0.702 ± 0.505
2.107TyrPro: 2.107 ± 1.271
2.809TyrGln: 2.809 ± 0.66
1.404TyrArg: 1.404 ± 0.592
1.404TyrSer: 1.404 ± 0.663
0.702TyrThr: 0.702 ± 0.505
4.213TyrVal: 4.213 ± 1.695
0.702TyrTrp: 0.702 ± 0.505
0.702TyrTyr: 0.702 ± 0.505
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1425 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski