Amino acid dipepetide frequency for Sporosarcina luteola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.401AlaAla: 6.401 ± 0.108
0.556AlaCys: 0.556 ± 0.02
3.969AlaAsp: 3.969 ± 0.075
5.535AlaGlu: 5.535 ± 0.084
3.527AlaPhe: 3.527 ± 0.06
5.569AlaGly: 5.569 ± 0.095
1.32AlaHis: 1.32 ± 0.033
6.378AlaIle: 6.378 ± 0.094
4.68AlaLys: 4.68 ± 0.065
7.64AlaLeu: 7.64 ± 0.11
2.299AlaMet: 2.299 ± 0.06
2.791AlaAsn: 2.791 ± 0.055
2.143AlaPro: 2.143 ± 0.047
2.239AlaGln: 2.239 ± 0.057
2.772AlaArg: 2.772 ± 0.056
4.41AlaSer: 4.41 ± 0.074
3.945AlaThr: 3.945 ± 0.07
5.769AlaVal: 5.769 ± 0.077
0.605AlaTrp: 0.605 ± 0.025
2.449AlaTyr: 2.449 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
0.392CysAla: 0.392 ± 0.021
0.071CysCys: 0.071 ± 0.008
0.324CysAsp: 0.324 ± 0.02
0.426CysGlu: 0.426 ± 0.02
0.242CysPhe: 0.242 ± 0.016
0.594CysGly: 0.594 ± 0.028
0.176CysHis: 0.176 ± 0.013
0.476CysIle: 0.476 ± 0.02
0.32CysLys: 0.32 ± 0.018
0.536CysLeu: 0.536 ± 0.025
0.139CysMet: 0.139 ± 0.012
0.263CysAsn: 0.263 ± 0.016
0.332CysPro: 0.332 ± 0.021
0.172CysGln: 0.172 ± 0.013
0.255CysArg: 0.255 ± 0.016
0.398CysSer: 0.398 ± 0.02
0.37CysThr: 0.37 ± 0.018
0.373CysVal: 0.373 ± 0.019
0.062CysTrp: 0.062 ± 0.007
0.197CysTyr: 0.197 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
3.983AspAla: 3.983 ± 0.076
0.35AspCys: 0.35 ± 0.019
2.874AspAsp: 2.874 ± 0.057
5.224AspGlu: 5.224 ± 0.081
2.557AspPhe: 2.557 ± 0.056
4.009AspGly: 4.009 ± 0.071
1.152AspHis: 1.152 ± 0.035
4.053AspIle: 4.053 ± 0.072
3.081AspLys: 3.081 ± 0.055
5.043AspLeu: 5.043 ± 0.077
1.507AspMet: 1.507 ± 0.039
1.813AspAsn: 1.813 ± 0.044
2.094AspPro: 2.094 ± 0.042
1.647AspGln: 1.647 ± 0.043
2.624AspArg: 2.624 ± 0.062
2.818AspSer: 2.818 ± 0.055
2.48AspThr: 2.48 ± 0.052
4.101AspVal: 4.101 ± 0.076
0.636AspTrp: 0.636 ± 0.023
2.05AspTyr: 2.05 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
5.773GluAla: 5.773 ± 0.079
0.353GluCys: 0.353 ± 0.023
4.066GluAsp: 4.066 ± 0.08
7.181GluGlu: 7.181 ± 0.103
2.656GluPhe: 2.656 ± 0.049
4.772GluGly: 4.772 ± 0.07
1.453GluHis: 1.453 ± 0.042
5.503GluIle: 5.503 ± 0.085
6.171GluLys: 6.171 ± 0.082
7.447GluLeu: 7.447 ± 0.095
2.755GluMet: 2.755 ± 0.053
3.394GluAsn: 3.394 ± 0.065
2.096GluPro: 2.096 ± 0.049
3.442GluGln: 3.442 ± 0.074
3.922GluArg: 3.922 ± 0.081
3.753GluSer: 3.753 ± 0.064
4.169GluThr: 4.169 ± 0.066
5.327GluVal: 5.327 ± 0.083
0.94GluTrp: 0.94 ± 0.033
2.086GluTyr: 2.086 ± 0.051
0.0GluXaa: 0.0 ± 0.0
Phe
3.312PheAla: 3.312 ± 0.071
0.308PheCys: 0.308 ± 0.017
2.59PheAsp: 2.59 ± 0.061
3.055PheGlu: 3.055 ± 0.061
2.323PhePhe: 2.323 ± 0.058
3.48PheGly: 3.48 ± 0.061
0.981PheHis: 0.981 ± 0.032
4.049PheIle: 4.049 ± 0.079
2.384PheLys: 2.384 ± 0.057
4.31PheLeu: 4.31 ± 0.073
1.353PheMet: 1.353 ± 0.033
1.89PheAsn: 1.89 ± 0.04
1.599PhePro: 1.599 ± 0.041
1.367PheGln: 1.367 ± 0.03
1.642PheArg: 1.642 ± 0.043
3.106PheSer: 3.106 ± 0.06
2.869PheThr: 2.869 ± 0.058
3.176PheVal: 3.176 ± 0.055
0.458PheTrp: 0.458 ± 0.022
1.588PheTyr: 1.588 ± 0.039
0.0PheXaa: 0.0 ± 0.0
Gly
5.032GlyAla: 5.032 ± 0.096
0.546GlyCys: 0.546 ± 0.024
3.556GlyAsp: 3.556 ± 0.069
4.897GlyGlu: 4.897 ± 0.082
3.473GlyPhe: 3.473 ± 0.058
4.982GlyGly: 4.982 ± 0.094
1.409GlyHis: 1.409 ± 0.041
6.024GlyIle: 6.024 ± 0.093
5.272GlyLys: 5.272 ± 0.081
6.497GlyLeu: 6.497 ± 0.105
2.4GlyMet: 2.4 ± 0.048
2.785GlyAsn: 2.785 ± 0.061
1.84GlyPro: 1.84 ± 0.054
2.255GlyGln: 2.255 ± 0.052
2.928GlyArg: 2.928 ± 0.061
4.055GlySer: 4.055 ± 0.064
4.206GlyThr: 4.206 ± 0.086
5.179GlyVal: 5.179 ± 0.08
0.785GlyTrp: 0.785 ± 0.03
2.682GlyTyr: 2.682 ± 0.057
0.0GlyXaa: 0.0 ± 0.0
His
1.51HisAla: 1.51 ± 0.04
0.158HisCys: 0.158 ± 0.012
1.014HisAsp: 1.014 ± 0.032
1.487HisGlu: 1.487 ± 0.04
1.061HisPhe: 1.061 ± 0.028
1.402HisGly: 1.402 ± 0.034
0.58HisHis: 0.58 ± 0.027
1.396HisIle: 1.396 ± 0.035
0.89HisLys: 0.89 ± 0.027
1.97HisLeu: 1.97 ± 0.044
0.534HisMet: 0.534 ± 0.022
0.677HisAsn: 0.677 ± 0.025
1.134HisPro: 1.134 ± 0.033
0.711HisGln: 0.711 ± 0.026
0.919HisArg: 0.919 ± 0.034
1.146HisSer: 1.146 ± 0.033
1.022HisThr: 1.022 ± 0.035
1.432HisVal: 1.432 ± 0.039
0.187HisTrp: 0.187 ± 0.013
0.838HisTyr: 0.838 ± 0.033
0.0HisXaa: 0.0 ± 0.0
Ile
6.63IleAla: 6.63 ± 0.092
0.544IleCys: 0.544 ± 0.024
4.545IleAsp: 4.545 ± 0.062
5.743IleGlu: 5.743 ± 0.081
3.222IlePhe: 3.222 ± 0.072
6.432IleGly: 6.432 ± 0.115
1.629IleHis: 1.629 ± 0.041
5.869IleIle: 5.869 ± 0.094
3.568IleLys: 3.568 ± 0.071
6.915IleLeu: 6.915 ± 0.099
1.86IleMet: 1.86 ± 0.044
2.674IleAsn: 2.674 ± 0.055
3.222IlePro: 3.222 ± 0.062
2.723IleGln: 2.723 ± 0.061
3.354IleArg: 3.354 ± 0.068
4.721IleSer: 4.721 ± 0.078
4.236IleThr: 4.236 ± 0.064
5.991IleVal: 5.991 ± 0.084
0.673IleTrp: 0.673 ± 0.028
2.26IleTyr: 2.26 ± 0.049
0.0IleXaa: 0.0 ± 0.0
Lys
4.485LysAla: 4.485 ± 0.069
0.264LysCys: 0.264 ± 0.016
3.602LysAsp: 3.602 ± 0.069
6.16LysGlu: 6.16 ± 0.092
1.933LysPhe: 1.933 ± 0.046
4.265LysGly: 4.265 ± 0.066
1.176LysHis: 1.176 ± 0.034
4.03LysIle: 4.03 ± 0.068
5.014LysLys: 5.014 ± 0.083
5.483LysLeu: 5.483 ± 0.072
2.441LysMet: 2.441 ± 0.053
2.817LysAsn: 2.817 ± 0.049
2.226LysPro: 2.226 ± 0.048
2.449LysGln: 2.449 ± 0.051
3.365LysArg: 3.365 ± 0.053
3.559LysSer: 3.559 ± 0.057
3.637LysThr: 3.637 ± 0.063
4.465LysVal: 4.465 ± 0.07
0.792LysTrp: 0.792 ± 0.033
1.884LysTyr: 1.884 ± 0.049
0.0LysXaa: 0.0 ± 0.0
Leu
7.468LeuAla: 7.468 ± 0.104
0.54LeuCys: 0.54 ± 0.023
4.849LeuAsp: 4.849 ± 0.071
6.344LeuGlu: 6.344 ± 0.089
4.959LeuPhe: 4.959 ± 0.085
6.065LeuGly: 6.065 ± 0.096
2.008LeuHis: 2.008 ± 0.047
7.043LeuIle: 7.043 ± 0.108
6.064LeuLys: 6.064 ± 0.094
10.32LeuLeu: 10.32 ± 0.139
2.577LeuMet: 2.577 ± 0.052
3.863LeuAsn: 3.863 ± 0.062
3.946LeuPro: 3.946 ± 0.062
3.534LeuGln: 3.534 ± 0.062
3.919LeuArg: 3.919 ± 0.071
6.799LeuSer: 6.799 ± 0.088
5.705LeuThr: 5.705 ± 0.067
6.116LeuVal: 6.116 ± 0.087
0.759LeuTrp: 0.759 ± 0.025
3.012LeuTyr: 3.012 ± 0.058
0.0LeuXaa: 0.0 ± 0.0
Met
2.272MetAla: 2.272 ± 0.051
0.129MetCys: 0.129 ± 0.01
1.863MetAsp: 1.863 ± 0.051
2.308MetGlu: 2.308 ± 0.05
1.118MetPhe: 1.118 ± 0.039
1.805MetGly: 1.805 ± 0.048
0.542MetHis: 0.542 ± 0.023
2.202MetIle: 2.202 ± 0.056
2.845MetLys: 2.845 ± 0.053
2.742MetLeu: 2.742 ± 0.052
1.0MetMet: 1.0 ± 0.034
1.666MetAsn: 1.666 ± 0.041
1.205MetPro: 1.205 ± 0.035
1.02MetGln: 1.02 ± 0.034
1.278MetArg: 1.278 ± 0.036
1.707MetSer: 1.707 ± 0.04
2.047MetThr: 2.047 ± 0.042
1.715MetVal: 1.715 ± 0.042
0.197MetTrp: 0.197 ± 0.015
0.828MetTyr: 0.828 ± 0.03
0.0MetXaa: 0.0 ± 0.0
Asn
2.977AsnAla: 2.977 ± 0.056
0.261AsnCys: 0.261 ± 0.017
2.238AsnAsp: 2.238 ± 0.054
3.606AsnGlu: 3.606 ± 0.069
1.529AsnPhe: 1.529 ± 0.036
3.319AsnGly: 3.319 ± 0.07
0.818AsnHis: 0.818 ± 0.034
2.818AsnIle: 2.818 ± 0.054
2.307AsnLys: 2.307 ± 0.052
3.469AsnLeu: 3.469 ± 0.067
1.225AsnMet: 1.225 ± 0.032
1.595AsnAsn: 1.595 ± 0.053
2.1AsnPro: 2.1 ± 0.05
1.363AsnGln: 1.363 ± 0.038
2.067AsnArg: 2.067 ± 0.043
2.105AsnSer: 2.105 ± 0.051
1.915AsnThr: 1.915 ± 0.046
2.887AsnVal: 2.887 ± 0.053
0.454AsnTrp: 0.454 ± 0.019
1.377AsnTyr: 1.377 ± 0.041
0.0AsnXaa: 0.0 ± 0.0
Pro
2.533ProAla: 2.533 ± 0.058
0.203ProCys: 0.203 ± 0.014
2.216ProAsp: 2.216 ± 0.05
3.059ProGlu: 3.059 ± 0.057
2.066ProPhe: 2.066 ± 0.053
2.377ProGly: 2.377 ± 0.052
0.795ProHis: 0.795 ± 0.03
2.938ProIle: 2.938 ± 0.056
1.947ProLys: 1.947 ± 0.044
3.439ProLeu: 3.439 ± 0.056
0.973ProMet: 0.973 ± 0.033
1.486ProAsn: 1.486 ± 0.045
1.035ProPro: 1.035 ± 0.037
1.026ProGln: 1.026 ± 0.035
1.07ProArg: 1.07 ± 0.036
2.322ProSer: 2.322 ± 0.053
2.002ProThr: 2.002 ± 0.055
3.018ProVal: 3.018 ± 0.063
0.305ProTrp: 0.305 ± 0.016
1.381ProTyr: 1.381 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
2.575GlnAla: 2.575 ± 0.045
0.163GlnCys: 0.163 ± 0.013
1.507GlnAsp: 1.507 ± 0.042
2.491GlnGlu: 2.491 ± 0.052
1.586GlnPhe: 1.586 ± 0.038
1.957GlnGly: 1.957 ± 0.072
0.657GlnHis: 0.657 ± 0.026
2.338GlnIle: 2.338 ± 0.045
2.328GlnLys: 2.328 ± 0.059
3.778GlnLeu: 3.778 ± 0.064
1.161GlnMet: 1.161 ± 0.035
1.342GlnAsn: 1.342 ± 0.038
1.177GlnPro: 1.177 ± 0.038
1.596GlnGln: 1.596 ± 0.038
1.495GlnArg: 1.495 ± 0.045
2.177GlnSer: 2.177 ± 0.053
1.932GlnThr: 1.932 ± 0.045
2.245GlnVal: 2.245 ± 0.049
0.369GlnTrp: 0.369 ± 0.018
1.153GlnTyr: 1.153 ± 0.036
0.0GlnXaa: 0.0 ± 0.0
Arg
2.792ArgAla: 2.792 ± 0.057
0.227ArgCys: 0.227 ± 0.018
2.168ArgAsp: 2.168 ± 0.052
3.343ArgGlu: 3.343 ± 0.062
2.117ArgPhe: 2.117 ± 0.049
2.484ArgGly: 2.484 ± 0.053
0.88ArgHis: 0.88 ± 0.027
3.231ArgIle: 3.231 ± 0.062
3.422ArgLys: 3.422 ± 0.061
4.394ArgLeu: 4.394 ± 0.068
1.517ArgMet: 1.517 ± 0.039
1.986ArgAsn: 1.986 ± 0.045
1.409ArgPro: 1.409 ± 0.03
1.731ArgGln: 1.731 ± 0.047
1.988ArgArg: 1.988 ± 0.053
2.343ArgSer: 2.343 ± 0.047
2.318ArgThr: 2.318 ± 0.053
2.774ArgVal: 2.774 ± 0.053
0.405ArgTrp: 0.405 ± 0.023
1.445ArgTyr: 1.445 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
4.151SerAla: 4.151 ± 0.069
0.323SerCys: 0.323 ± 0.016
3.071SerAsp: 3.071 ± 0.057
3.997SerGlu: 3.997 ± 0.066
3.368SerPhe: 3.368 ± 0.056
4.654SerGly: 4.654 ± 0.068
1.119SerHis: 1.119 ± 0.03
5.128SerIle: 5.128 ± 0.072
3.457SerLys: 3.457 ± 0.067
5.808SerLeu: 5.808 ± 0.068
1.949SerMet: 1.949 ± 0.046
2.33SerAsn: 2.33 ± 0.052
2.116SerPro: 2.116 ± 0.045
1.679SerGln: 1.679 ± 0.044
2.462SerArg: 2.462 ± 0.05
3.751SerSer: 3.751 ± 0.063
3.259SerThr: 3.259 ± 0.051
4.317SerVal: 4.317 ± 0.066
0.568SerTrp: 0.568 ± 0.026
2.036SerTyr: 2.036 ± 0.051
0.0SerXaa: 0.0 ± 0.0
Thr
4.48ThrAla: 4.48 ± 0.073
0.308ThrCys: 0.308 ± 0.016
3.195ThrAsp: 3.195 ± 0.072
4.014ThrGlu: 4.014 ± 0.071
2.665ThrPhe: 2.665 ± 0.048
4.574ThrGly: 4.574 ± 0.103
1.099ThrHis: 1.099 ± 0.033
4.572ThrIle: 4.572 ± 0.07
3.138ThrLys: 3.138 ± 0.052
5.026ThrLeu: 5.026 ± 0.075
1.501ThrMet: 1.501 ± 0.044
2.193ThrAsn: 2.193 ± 0.05
2.268ThrPro: 2.268 ± 0.045
1.358ThrGln: 1.358 ± 0.04
1.917ThrArg: 1.917 ± 0.036
3.213ThrSer: 3.213 ± 0.06
3.099ThrThr: 3.099 ± 0.057
4.88ThrVal: 4.88 ± 0.077
0.492ThrTrp: 0.492 ± 0.021
1.941ThrTyr: 1.941 ± 0.052
0.0ThrXaa: 0.0 ± 0.0
Val
5.317ValAla: 5.317 ± 0.078
0.503ValCys: 0.503 ± 0.023
3.983ValAsp: 3.983 ± 0.069
5.21ValGlu: 5.21 ± 0.078
3.248ValPhe: 3.248 ± 0.058
4.909ValGly: 4.909 ± 0.082
1.428ValHis: 1.428 ± 0.037
5.626ValIle: 5.626 ± 0.073
4.581ValLys: 4.581 ± 0.079
6.937ValLeu: 6.937 ± 0.098
2.027ValMet: 2.027 ± 0.048
3.103ValAsn: 3.103 ± 0.057
2.65ValPro: 2.65 ± 0.052
2.357ValGln: 2.357 ± 0.051
2.95ValArg: 2.95 ± 0.053
4.533ValSer: 4.533 ± 0.068
4.375ValThr: 4.375 ± 0.081
5.198ValVal: 5.198 ± 0.084
0.647ValTrp: 0.647 ± 0.029
2.161ValTyr: 2.161 ± 0.046
0.0ValXaa: 0.0 ± 0.0
Trp
0.608TrpAla: 0.608 ± 0.026
0.062TrpCys: 0.062 ± 0.007
0.503TrpAsp: 0.503 ± 0.023
0.624TrpGlu: 0.624 ± 0.027
0.466TrpPhe: 0.466 ± 0.02
0.65TrpGly: 0.65 ± 0.025
0.215TrpHis: 0.215 ± 0.012
0.82TrpIle: 0.82 ± 0.032
0.703TrpLys: 0.703 ± 0.026
1.068TrpLeu: 1.068 ± 0.038
0.372TrpMet: 0.372 ± 0.018
0.503TrpAsn: 0.503 ± 0.024
0.28TrpPro: 0.28 ± 0.02
0.336TrpGln: 0.336 ± 0.019
0.436TrpArg: 0.436 ± 0.022
0.574TrpSer: 0.574 ± 0.02
0.572TrpThr: 0.572 ± 0.025
0.607TrpVal: 0.607 ± 0.024
0.126TrpTrp: 0.126 ± 0.012
0.288TrpTyr: 0.288 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.303TyrAla: 2.303 ± 0.049
0.25TyrCys: 0.25 ± 0.017
1.963TyrAsp: 1.963 ± 0.044
2.554TyrGlu: 2.554 ± 0.058
1.725TyrPhe: 1.725 ± 0.037
2.502TyrGly: 2.502 ± 0.047
0.633TyrHis: 0.633 ± 0.026
2.317TyrIle: 2.317 ± 0.047
1.874TyrLys: 1.874 ± 0.046
3.07TyrLeu: 3.07 ± 0.053
0.898TyrMet: 0.898 ± 0.032
1.262TyrAsn: 1.262 ± 0.034
1.317TyrPro: 1.317 ± 0.034
1.02TyrGln: 1.02 ± 0.034
1.611TyrArg: 1.611 ± 0.041
2.056TyrSer: 2.056 ± 0.054
1.773TyrThr: 1.773 ± 0.046
2.173TyrVal: 2.173 ± 0.048
0.355TyrTrp: 0.355 ± 0.019
1.271TyrTyr: 1.271 ± 0.041
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3572 proteins (1034920 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski