Amino acid dipepetide frequency for Marinobacter litoralis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.609AlaAla: 9.609 ± 0.119	1.003AlaCys: 1.003 ± 0.035	5.45AlaAsp: 5.45 ± 0.076	6.743AlaGlu: 6.743 ± 0.091	3.644AlaPhe: 3.644 ± 0.059	8.055AlaGly: 8.055 ± 0.093	1.862AlaHis: 1.862 ± 0.042	5.478AlaIle: 5.478 ± 0.078	3.881AlaLys: 3.881 ± 0.059	11.062AlaLeu: 11.062 ± 0.12	2.966AlaMet: 2.966 ± 0.053	3.198AlaAsn: 3.198 ± 0.06	3.882AlaPro: 3.882 ± 0.071	3.649AlaGln: 3.649 ± 0.058	5.812AlaArg: 5.812 ± 0.085	5.738AlaSer: 5.738 ± 0.083	4.666AlaThr: 4.666 ± 0.073	7.011AlaVal: 7.011 ± 0.083	1.323AlaTrp: 1.323 ± 0.034	2.208AlaTyr: 2.208 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.792CysAla: 0.792 ± 0.029	0.116CysCys: 0.116 ± 0.011	0.547CysAsp: 0.547 ± 0.023	0.581CysGlu: 0.581 ± 0.022	0.353CysPhe: 0.353 ± 0.018	0.843CysGly: 0.843 ± 0.034	0.314CysHis: 0.314 ± 0.018	0.416CysIle: 0.416 ± 0.019	0.347CysLys: 0.347 ± 0.02	0.904CysLeu: 0.904 ± 0.03	0.181CysMet: 0.181 ± 0.014	0.266CysAsn: 0.266 ± 0.016	0.485CysPro: 0.485 ± 0.024	0.384CysGln: 0.384 ± 0.018	0.589CysArg: 0.589 ± 0.024	0.573CysSer: 0.573 ± 0.024	0.431CysThr: 0.431 ± 0.022	0.648CysVal: 0.648 ± 0.025	0.12CysTrp: 0.12 ± 0.011	0.246CysTyr: 0.246 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	5.054AspAla: 5.054 ± 0.074	0.472AspCys: 0.472 ± 0.024	3.301AspAsp: 3.301 ± 0.063	4.151AspGlu: 4.151 ± 0.059	2.24AspPhe: 2.24 ± 0.046	4.309AspGly: 4.309 ± 0.089	1.33AspHis: 1.33 ± 0.032	3.285AspIle: 3.285 ± 0.054	2.195AspLys: 2.195 ± 0.053	5.715AspLeu: 5.715 ± 0.083	1.44AspMet: 1.44 ± 0.039	2.051AspAsn: 2.051 ± 0.075	2.673AspPro: 2.673 ± 0.054	2.405AspGln: 2.405 ± 0.049	3.421AspArg: 3.421 ± 0.067	3.144AspSer: 3.144 ± 0.054	2.908AspThr: 2.908 ± 0.059	4.087AspVal: 4.087 ± 0.061	0.929AspTrp: 0.929 ± 0.033	1.809AspTyr: 1.809 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	6.866GluAla: 6.866 ± 0.093	0.485GluCys: 0.485 ± 0.022	3.425GluAsp: 3.425 ± 0.062	4.221GluGlu: 4.221 ± 0.083	2.347GluPhe: 2.347 ± 0.051	4.549GluGly: 4.549 ± 0.069	1.709GluHis: 1.709 ± 0.039	3.361GluIle: 3.361 ± 0.063	3.137GluLys: 3.137 ± 0.067	7.446GluLeu: 7.446 ± 0.092	1.634GluMet: 1.634 ± 0.04	2.423GluAsn: 2.423 ± 0.051	2.936GluPro: 2.936 ± 0.066	3.893GluGln: 3.893 ± 0.074	4.576GluArg: 4.576 ± 0.076	3.588GluSer: 3.588 ± 0.062	3.537GluThr: 3.537 ± 0.063	4.722GluVal: 4.722 ± 0.081	0.831GluTrp: 0.831 ± 0.029	1.527GluTyr: 1.527 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.386PheAla: 3.386 ± 0.066	0.411PheCys: 0.411 ± 0.018	2.422PheAsp: 2.422 ± 0.051	2.471PheGlu: 2.471 ± 0.053	1.558PhePhe: 1.558 ± 0.045	3.268PheGly: 3.268 ± 0.055	0.799PheHis: 0.799 ± 0.029	1.994PheIle: 1.994 ± 0.045	1.326PheLys: 1.326 ± 0.035	3.536PheLeu: 3.536 ± 0.066	0.972PheMet: 0.972 ± 0.034	1.409PheAsn: 1.409 ± 0.037	1.585PhePro: 1.585 ± 0.04	1.251PheGln: 1.251 ± 0.036	2.347PheArg: 2.347 ± 0.046	2.764PheSer: 2.764 ± 0.053	2.124PheThr: 2.124 ± 0.042	2.723PheVal: 2.723 ± 0.049	0.519PheTrp: 0.519 ± 0.025	1.118PheTyr: 1.118 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	6.71GlyAla: 6.71 ± 0.091	0.913GlyCys: 0.913 ± 0.032	4.256GlyAsp: 4.256 ± 0.067	5.029GlyGlu: 5.029 ± 0.067	3.365GlyPhe: 3.365 ± 0.057	5.815GlyGly: 5.815 ± 0.106	1.799GlyHis: 1.799 ± 0.043	4.556GlyIle: 4.556 ± 0.071	3.601GlyLys: 3.601 ± 0.06	8.382GlyLeu: 8.382 ± 0.111	2.276GlyMet: 2.276 ± 0.044	2.511GlyAsn: 2.511 ± 0.06	2.443GlyPro: 2.443 ± 0.053	3.288GlyGln: 3.288 ± 0.064	4.42GlyArg: 4.42 ± 0.071	4.483GlySer: 4.483 ± 0.072	3.803GlyThr: 3.803 ± 0.061	5.875GlyVal: 5.875 ± 0.08	1.172GlyTrp: 1.172 ± 0.038	2.431GlyTyr: 2.431 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.873HisAla: 1.873 ± 0.038	0.279HisCys: 0.279 ± 0.017	1.162HisAsp: 1.162 ± 0.033	1.221HisGlu: 1.221 ± 0.037	0.949HisPhe: 0.949 ± 0.031	1.784HisGly: 1.784 ± 0.045	0.678HisHis: 0.678 ± 0.025	1.127HisIle: 1.127 ± 0.032	0.769HisLys: 0.769 ± 0.03	2.231HisLeu: 2.231 ± 0.049	0.52HisMet: 0.52 ± 0.021	0.727HisAsn: 0.727 ± 0.029	1.379HisPro: 1.379 ± 0.036	1.006HisGln: 1.006 ± 0.033	1.465HisArg: 1.465 ± 0.037	1.275HisSer: 1.275 ± 0.03	1.103HisThr: 1.103 ± 0.034	1.283HisVal: 1.283 ± 0.032	0.389HisTrp: 0.389 ± 0.018	0.762HisTyr: 0.762 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.488IleAla: 5.488 ± 0.085	0.486IleCys: 0.486 ± 0.021	3.313IleAsp: 3.313 ± 0.053	3.837IleGlu: 3.837 ± 0.063	1.686IlePhe: 1.686 ± 0.043	4.269IleGly: 4.269 ± 0.079	1.113IleHis: 1.113 ± 0.033	2.588IleIle: 2.588 ± 0.058	2.029IleLys: 2.029 ± 0.043	4.656IleLeu: 4.656 ± 0.081	1.095IleMet: 1.095 ± 0.034	2.019IleAsn: 2.019 ± 0.05	2.64IlePro: 2.64 ± 0.054	1.858IleGln: 1.858 ± 0.043	3.5IleArg: 3.5 ± 0.05	3.355IleSer: 3.355 ± 0.059	2.997IleThr: 2.997 ± 0.051	3.684IleVal: 3.684 ± 0.068	0.555IleTrp: 0.555 ± 0.022	1.252IleTyr: 1.252 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.506LysAla: 4.506 ± 0.064	0.243LysCys: 0.243 ± 0.016	2.284LysAsp: 2.284 ± 0.052	2.594LysGlu: 2.594 ± 0.059	1.122LysPhe: 1.122 ± 0.03	2.976LysGly: 2.976 ± 0.063	0.876LysHis: 0.876 ± 0.026	1.87LysIle: 1.87 ± 0.047	1.916LysLys: 1.916 ± 0.057	4.29LysLeu: 4.29 ± 0.057	0.91LysMet: 0.91 ± 0.026	1.338LysAsn: 1.338 ± 0.042	2.305LysPro: 2.305 ± 0.055	1.894LysGln: 1.894 ± 0.044	2.574LysArg: 2.574 ± 0.055	2.191LysSer: 2.191 ± 0.049	2.32LysThr: 2.32 ± 0.049	3.145LysVal: 3.145 ± 0.059	0.407LysTrp: 0.407 ± 0.021	0.887LysTyr: 0.887 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	11.719LeuAla: 11.719 ± 0.145	0.952LeuCys: 0.952 ± 0.028	6.062LeuAsp: 6.062 ± 0.087	7.11LeuGlu: 7.11 ± 0.089	3.946LeuPhe: 3.946 ± 0.067	7.695LeuGly: 7.695 ± 0.094	1.993LeuHis: 1.993 ± 0.048	5.386LeuIle: 5.386 ± 0.085	4.769LeuLys: 4.769 ± 0.07	10.57LeuLeu: 10.57 ± 0.154	2.81LeuMet: 2.81 ± 0.053	3.946LeuAsn: 3.946 ± 0.057	5.369LeuPro: 5.369 ± 0.083	3.806LeuGln: 3.806 ± 0.063	5.96LeuArg: 5.96 ± 0.083	7.0LeuSer: 7.0 ± 0.101	5.796LeuThr: 5.796 ± 0.073	7.555LeuVal: 7.555 ± 0.095	1.247LeuTrp: 1.247 ± 0.036	2.342LeuTyr: 2.342 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	3.08MetAla: 3.08 ± 0.055	0.189MetCys: 0.189 ± 0.014	1.34MetAsp: 1.34 ± 0.038	1.435MetGlu: 1.435 ± 0.038	0.772MetPhe: 0.772 ± 0.028	2.025MetGly: 2.025 ± 0.046	0.478MetHis: 0.478 ± 0.021	1.301MetIle: 1.301 ± 0.037	1.27MetLys: 1.27 ± 0.031	2.649MetLeu: 2.649 ± 0.056	0.698MetMet: 0.698 ± 0.027	1.017MetAsn: 1.017 ± 0.032	1.378MetPro: 1.378 ± 0.035	0.965MetGln: 0.965 ± 0.028	1.362MetArg: 1.362 ± 0.041	1.749MetSer: 1.749 ± 0.037	1.684MetThr: 1.684 ± 0.035	1.911MetVal: 1.911 ± 0.047	0.182MetTrp: 0.182 ± 0.014	0.445MetTyr: 0.445 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.194AsnAla: 3.194 ± 0.064	0.325AsnCys: 0.325 ± 0.018	1.932AsnAsp: 1.932 ± 0.047	2.089AsnGlu: 2.089 ± 0.046	1.198AsnPhe: 1.198 ± 0.033	2.809AsnGly: 2.809 ± 0.053	0.798AsnHis: 0.798 ± 0.027	1.79AsnIle: 1.79 ± 0.046	1.235AsnLys: 1.235 ± 0.035	3.668AsnLeu: 3.668 ± 0.063	0.847AsnMet: 0.847 ± 0.026	1.229AsnAsn: 1.229 ± 0.043	2.181AsnPro: 2.181 ± 0.048	1.464AsnGln: 1.464 ± 0.036	2.307AsnArg: 2.307 ± 0.047	1.872AsnSer: 1.872 ± 0.064	1.831AsnThr: 1.831 ± 0.043	2.296AsnVal: 2.296 ± 0.047	0.537AsnTrp: 0.537 ± 0.023	0.936AsnTyr: 0.936 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	4.555ProAla: 4.555 ± 0.076	0.316ProCys: 0.316 ± 0.02	3.364ProAsp: 3.364 ± 0.056	4.638ProGlu: 4.638 ± 0.08	1.794ProPhe: 1.794 ± 0.05	3.789ProGly: 3.789 ± 0.066	0.894ProHis: 0.894 ± 0.032	2.166ProIle: 2.166 ± 0.045	1.873ProLys: 1.873 ± 0.05	4.608ProLeu: 4.608 ± 0.064	1.131ProMet: 1.131 ± 0.03	1.491ProAsn: 1.491 ± 0.037	1.651ProPro: 1.651 ± 0.041	1.478ProGln: 1.478 ± 0.043	2.046ProArg: 2.046 ± 0.046	2.608ProSer: 2.608 ± 0.05	2.03ProThr: 2.03 ± 0.045	4.204ProVal: 4.204 ± 0.068	0.694ProTrp: 0.694 ± 0.026	1.117ProTyr: 1.117 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.452GlnAla: 4.452 ± 0.072	0.327GlnCys: 0.327 ± 0.02	1.879GlnAsp: 1.879 ± 0.043	2.42GlnGlu: 2.42 ± 0.062	1.493GlnPhe: 1.493 ± 0.039	3.028GlnGly: 3.028 ± 0.054	0.947GlnHis: 0.947 ± 0.033	1.973GlnIle: 1.973 ± 0.044	1.688GlnLys: 1.688 ± 0.042	4.388GlnLeu: 4.388 ± 0.081	1.017GlnMet: 1.017 ± 0.03	1.355GlnAsn: 1.355 ± 0.036	2.062GlnPro: 2.062 ± 0.046	2.25GlnGln: 2.25 ± 0.064	2.793GlnArg: 2.793 ± 0.055	2.419GlnSer: 2.419 ± 0.052	2.018GlnThr: 2.018 ± 0.042	3.015GlnVal: 3.015 ± 0.049	0.671GlnTrp: 0.671 ± 0.026	1.015GlnTyr: 1.015 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	5.045ArgAla: 5.045 ± 0.078	0.545ArgCys: 0.545 ± 0.022	3.363ArgAsp: 3.363 ± 0.059	4.324ArgGlu: 4.324 ± 0.065	2.774ArgPhe: 2.774 ± 0.055	3.531ArgGly: 3.531 ± 0.06	1.437ArgHis: 1.437 ± 0.039	3.503ArgIle: 3.503 ± 0.058	2.879ArgLys: 2.879 ± 0.057	6.775ArgLeu: 6.775 ± 0.088	1.654ArgMet: 1.654 ± 0.039	2.206ArgAsn: 2.206 ± 0.045	2.465ArgPro: 2.465 ± 0.056	2.953ArgGln: 2.953 ± 0.058	3.802ArgArg: 3.802 ± 0.068	3.384ArgSer: 3.384 ± 0.07	2.768ArgThr: 2.768 ± 0.043	4.345ArgVal: 4.345 ± 0.063	0.971ArgTrp: 0.971 ± 0.031	2.044ArgTyr: 2.044 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.661SerAla: 5.661 ± 0.08	0.479SerCys: 0.479 ± 0.023	3.583SerAsp: 3.583 ± 0.074	4.039SerGlu: 4.039 ± 0.067	2.247SerPhe: 2.247 ± 0.056	5.561SerGly: 5.561 ± 0.084	1.364SerHis: 1.364 ± 0.041	2.973SerIle: 2.973 ± 0.058	2.174SerLys: 2.174 ± 0.05	6.387SerLeu: 6.387 ± 0.083	1.623SerMet: 1.623 ± 0.034	1.875SerAsn: 1.875 ± 0.048	2.695SerPro: 2.695 ± 0.049	2.267SerGln: 2.267 ± 0.052	3.673SerArg: 3.673 ± 0.061	3.725SerSer: 3.725 ± 0.064	2.863SerThr: 2.863 ± 0.054	4.455SerVal: 4.455 ± 0.072	0.829SerTrp: 0.829 ± 0.03	1.517SerTyr: 1.517 ± 0.037	0.001SerXaa: 0.001 ± 0.001
Thr	4.806ThrAla: 4.806 ± 0.074	0.462ThrCys: 0.462 ± 0.021	2.949ThrAsp: 2.949 ± 0.057	3.249ThrGlu: 3.249 ± 0.058	1.906ThrPhe: 1.906 ± 0.043	4.821ThrGly: 4.821 ± 0.075	1.108ThrHis: 1.108 ± 0.032	2.577ThrIle: 2.577 ± 0.047	1.548ThrLys: 1.548 ± 0.043	6.296ThrLeu: 6.296 ± 0.099	1.152ThrMet: 1.152 ± 0.036	1.591ThrAsn: 1.591 ± 0.045	2.992ThrPro: 2.992 ± 0.052	1.741ThrGln: 1.741 ± 0.043	3.037ThrArg: 3.037 ± 0.055	2.947ThrSer: 2.947 ± 0.052	2.678ThrThr: 2.678 ± 0.056	4.011ThrVal: 4.011 ± 0.067	0.618ThrTrp: 0.618 ± 0.024	1.215ThrTyr: 1.215 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	7.33ValAla: 7.33 ± 0.085	0.718ValCys: 0.718 ± 0.027	4.194ValAsp: 4.194 ± 0.067	4.79ValGlu: 4.79 ± 0.067	2.956ValPhe: 2.956 ± 0.058	5.04ValGly: 5.04 ± 0.08	1.492ValHis: 1.492 ± 0.042	4.296ValIle: 4.296 ± 0.068	2.714ValLys: 2.714 ± 0.056	7.484ValLeu: 7.484 ± 0.088	2.101ValMet: 2.101 ± 0.04	2.595ValAsn: 2.595 ± 0.044	3.386ValPro: 3.386 ± 0.064	2.465ValGln: 2.465 ± 0.05	4.297ValArg: 4.297 ± 0.071	4.859ValSer: 4.859 ± 0.075	4.231ValThr: 4.231 ± 0.056	5.977ValVal: 5.977 ± 0.098	0.865ValTrp: 0.865 ± 0.031	1.743ValTyr: 1.743 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.024TrpAla: 1.024 ± 0.03	0.139TrpCys: 0.139 ± 0.012	0.605TrpAsp: 0.605 ± 0.026	0.655TrpGlu: 0.655 ± 0.027	0.618TrpPhe: 0.618 ± 0.027	0.884TrpGly: 0.884 ± 0.03	0.393TrpHis: 0.393 ± 0.023	0.66TrpIle: 0.66 ± 0.026	0.451TrpLys: 0.451 ± 0.024	2.027TrpLeu: 2.027 ± 0.058	0.363TrpMet: 0.363 ± 0.017	0.438TrpAsn: 0.438 ± 0.024	0.604TrpPro: 0.604 ± 0.026	0.865TrpGln: 0.865 ± 0.029	0.865TrpArg: 0.865 ± 0.034	0.768TrpSer: 0.768 ± 0.029	0.597TrpThr: 0.597 ± 0.024	0.965TrpVal: 0.965 ± 0.033	0.215TrpTrp: 0.215 ± 0.014	0.328TrpTyr: 0.328 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.091TyrAla: 2.091 ± 0.042	0.277TyrCys: 0.277 ± 0.018	1.49TyrAsp: 1.49 ± 0.038	1.617TyrGlu: 1.617 ± 0.042	1.02TyrPhe: 1.02 ± 0.033	2.075TyrGly: 2.075 ± 0.049	0.599TyrHis: 0.599 ± 0.023	1.121TyrIle: 1.121 ± 0.037	0.847TyrLys: 0.847 ± 0.03	2.959TyrLeu: 2.959 ± 0.052	0.536TyrMet: 0.536 ± 0.023	0.857TyrAsn: 0.857 ± 0.031	1.331TyrPro: 1.331 ± 0.037	1.326TyrGln: 1.326 ± 0.037	1.917TyrArg: 1.917 ± 0.041	1.55TyrSer: 1.55 ± 0.037	1.319TyrThr: 1.319 ± 0.037	1.621TyrVal: 1.621 ± 0.039	0.391TyrTrp: 0.391 ± 0.02	0.767TyrTyr: 0.767 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3156 proteins (1057142 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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