Amino acid dipepetide frequency for Eggplant mottled dwarf nucleorhabdovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.288AlaAla: 4.288 ± 1.76
0.504AlaCys: 0.504 ± 0.269
4.54AlaAsp: 4.54 ± 1.391
3.531AlaGlu: 3.531 ± 1.25
1.765AlaPhe: 1.765 ± 0.345
1.513AlaGly: 1.513 ± 0.928
1.261AlaHis: 1.261 ± 0.745
3.279AlaIle: 3.279 ± 0.44
3.783AlaLys: 3.783 ± 1.425
4.54AlaLeu: 4.54 ± 1.133
1.009AlaMet: 1.009 ± 0.438
2.27AlaAsn: 2.27 ± 1.266
2.27AlaPro: 2.27 ± 0.378
0.504AlaGln: 0.504 ± 0.487
1.765AlaArg: 1.765 ± 0.649
4.54AlaSer: 4.54 ± 1.046
2.774AlaThr: 2.774 ± 0.553
3.783AlaVal: 3.783 ± 0.944
0.252AlaTrp: 0.252 ± 0.322
2.018AlaTyr: 2.018 ± 0.902
0.0AlaXaa: 0.0 ± 0.0
Cys
1.009CysAla: 1.009 ± 0.339
0.252CysCys: 0.252 ± 0.149
1.009CysAsp: 1.009 ± 0.339
0.0CysGlu: 0.0 ± 0.0
0.757CysPhe: 0.757 ± 0.447
0.252CysGly: 0.252 ± 0.322
0.252CysHis: 0.252 ± 0.149
1.765CysIle: 1.765 ± 0.491
0.757CysLys: 0.757 ± 0.258
2.018CysLeu: 2.018 ± 0.671
1.261CysMet: 1.261 ± 0.263
1.009CysAsn: 1.009 ± 0.742
1.765CysPro: 1.765 ± 0.636
0.0CysGln: 0.0 ± 0.0
1.261CysArg: 1.261 ± 0.448
1.513CysSer: 1.513 ± 0.587
0.504CysThr: 0.504 ± 0.251
1.009CysVal: 1.009 ± 0.339
0.0CysTrp: 0.0 ± 0.0
0.252CysTyr: 0.252 ± 0.149
0.0CysXaa: 0.0 ± 0.0
Asp
4.54AspAla: 4.54 ± 0.796
1.261AspCys: 1.261 ± 0.455
5.044AspAsp: 5.044 ± 1.364
3.026AspGlu: 3.026 ± 0.853
1.513AspPhe: 1.513 ± 0.59
2.27AspGly: 2.27 ± 0.684
1.765AspHis: 1.765 ± 0.469
6.557AspIle: 6.557 ± 0.96
3.783AspLys: 3.783 ± 0.497
5.549AspLeu: 5.549 ± 0.941
2.27AspMet: 2.27 ± 0.892
2.774AspAsn: 2.774 ± 0.706
3.531AspPro: 3.531 ± 0.806
2.27AspGln: 2.27 ± 0.323
2.522AspArg: 2.522 ± 0.683
4.792AspSer: 4.792 ± 1.021
3.531AspThr: 3.531 ± 2.075
4.54AspVal: 4.54 ± 0.673
1.009AspTrp: 1.009 ± 0.596
1.765AspTyr: 1.765 ± 0.413
0.0AspXaa: 0.0 ± 0.0
Glu
3.279GluAla: 3.279 ± 0.418
1.261GluCys: 1.261 ± 0.429
3.783GluAsp: 3.783 ± 1.291
4.035GluGlu: 4.035 ± 0.778
1.513GluPhe: 1.513 ± 0.378
6.053GluGly: 6.053 ± 0.329
0.757GluHis: 0.757 ± 0.447
4.54GluIle: 4.54 ± 1.178
3.783GluLys: 3.783 ± 0.884
3.531GluLeu: 3.531 ± 0.966
2.522GluMet: 2.522 ± 0.692
1.513GluAsn: 1.513 ± 0.51
1.009GluPro: 1.009 ± 0.42
1.009GluGln: 1.009 ± 0.78
3.783GluArg: 3.783 ± 1.262
4.035GluSer: 4.035 ± 0.982
3.783GluThr: 3.783 ± 1.042
2.27GluVal: 2.27 ± 0.367
1.261GluTrp: 1.261 ± 0.436
1.513GluTyr: 1.513 ± 0.392
0.0GluXaa: 0.0 ± 0.0
Phe
1.009PheAla: 1.009 ± 0.82
0.504PheCys: 0.504 ± 0.316
1.765PheAsp: 1.765 ± 0.515
1.765PheGlu: 1.765 ± 0.695
1.009PhePhe: 1.009 ± 0.295
1.513PheGly: 1.513 ± 0.365
0.252PheHis: 0.252 ± 0.281
2.522PheIle: 2.522 ± 0.603
1.261PheLys: 1.261 ± 0.538
3.026PheLeu: 3.026 ± 0.78
2.018PheMet: 2.018 ± 0.313
2.018PheAsn: 2.018 ± 0.476
1.765PhePro: 1.765 ± 0.487
1.513PheGln: 1.513 ± 0.549
1.765PheArg: 1.765 ± 0.351
4.288PheSer: 4.288 ± 0.788
1.765PheThr: 1.765 ± 0.847
1.765PheVal: 1.765 ± 0.507
0.504PheTrp: 0.504 ± 0.251
2.018PheTyr: 2.018 ± 0.605
0.0PheXaa: 0.0 ± 0.0
Gly
1.009GlyAla: 1.009 ± 0.348
0.252GlyCys: 0.252 ± 0.149
3.531GlyAsp: 3.531 ± 0.779
3.531GlyGlu: 3.531 ± 0.6
2.018GlyPhe: 2.018 ± 0.448
4.288GlyGly: 4.288 ± 0.644
1.513GlyHis: 1.513 ± 0.54
4.54GlyIle: 4.54 ± 1.259
3.026GlyLys: 3.026 ± 0.526
4.288GlyLeu: 4.288 ± 1.151
2.522GlyMet: 2.522 ± 0.787
2.27GlyAsn: 2.27 ± 0.798
3.026GlyPro: 3.026 ± 0.666
1.261GlyGln: 1.261 ± 0.588
3.783GlyArg: 3.783 ± 0.846
4.54GlySer: 4.54 ± 1.043
2.774GlyThr: 2.774 ± 0.816
5.044GlyVal: 5.044 ± 1.087
1.261GlyTrp: 1.261 ± 0.455
2.27GlyTyr: 2.27 ± 0.63
0.0GlyXaa: 0.0 ± 0.0
His
1.765HisAla: 1.765 ± 0.439
0.252HisCys: 0.252 ± 0.322
1.765HisAsp: 1.765 ± 0.531
1.765HisGlu: 1.765 ± 1.043
1.009HisPhe: 1.009 ± 0.596
2.018HisGly: 2.018 ± 0.578
0.757HisHis: 0.757 ± 0.332
3.026HisIle: 3.026 ± 0.952
0.252HisLys: 0.252 ± 0.149
2.27HisLeu: 2.27 ± 0.712
0.757HisMet: 0.757 ± 0.377
0.757HisAsn: 0.757 ± 0.447
1.513HisPro: 1.513 ± 0.7
0.504HisGln: 0.504 ± 0.298
0.757HisArg: 0.757 ± 0.332
1.513HisSer: 1.513 ± 0.665
0.757HisThr: 0.757 ± 0.332
1.513HisVal: 1.513 ± 0.347
0.252HisTrp: 0.252 ± 0.281
0.504HisTyr: 0.504 ± 0.265
0.0HisXaa: 0.0 ± 0.0
Ile
3.531IleAla: 3.531 ± 0.898
1.765IleCys: 1.765 ± 0.351
4.035IleAsp: 4.035 ± 1.209
3.783IleGlu: 3.783 ± 0.685
3.026IlePhe: 3.026 ± 0.489
4.288IleGly: 4.288 ± 0.809
2.522IleHis: 2.522 ± 0.923
5.296IleIle: 5.296 ± 0.843
3.783IleLys: 3.783 ± 1.467
6.81IleLeu: 6.81 ± 0.846
3.279IleMet: 3.279 ± 0.542
3.026IleAsn: 3.026 ± 0.729
3.279IlePro: 3.279 ± 0.786
3.279IleGln: 3.279 ± 0.874
3.279IleArg: 3.279 ± 0.821
8.071IleSer: 8.071 ± 1.301
7.314IleThr: 7.314 ± 0.968
4.035IleVal: 4.035 ± 0.594
1.009IleTrp: 1.009 ± 0.613
3.531IleTyr: 3.531 ± 0.939
0.0IleXaa: 0.0 ± 0.0
Lys
2.774LysAla: 2.774 ± 0.784
0.757LysCys: 0.757 ± 0.447
2.522LysAsp: 2.522 ± 1.329
3.783LysGlu: 3.783 ± 1.099
2.774LysPhe: 2.774 ± 0.874
2.522LysGly: 2.522 ± 0.813
1.513LysHis: 1.513 ± 0.501
5.044LysIle: 5.044 ± 1.001
3.279LysLys: 3.279 ± 0.828
4.54LysLeu: 4.54 ± 0.738
1.765LysMet: 1.765 ± 0.485
4.035LysAsn: 4.035 ± 0.984
2.774LysPro: 2.774 ± 0.925
1.009LysGln: 1.009 ± 0.362
3.279LysArg: 3.279 ± 0.808
4.288LysSer: 4.288 ± 1.83
3.783LysThr: 3.783 ± 0.805
2.27LysVal: 2.27 ± 0.739
0.757LysTrp: 0.757 ± 0.558
2.018LysTyr: 2.018 ± 0.887
0.0LysXaa: 0.0 ± 0.0
Leu
3.783LeuAla: 3.783 ± 0.67
1.765LeuCys: 1.765 ± 0.584
3.279LeuAsp: 3.279 ± 0.87
5.296LeuGlu: 5.296 ± 0.627
1.513LeuPhe: 1.513 ± 0.54
6.053LeuGly: 6.053 ± 0.997
2.774LeuHis: 2.774 ± 1.083
4.035LeuIle: 4.035 ± 0.626
6.053LeuLys: 6.053 ± 2.038
8.827LeuLeu: 8.827 ± 1.113
4.035LeuMet: 4.035 ± 1.34
4.288LeuAsn: 4.288 ± 0.888
3.531LeuPro: 3.531 ± 0.633
3.783LeuGln: 3.783 ± 0.752
3.026LeuArg: 3.026 ± 1.126
8.575LeuSer: 8.575 ± 0.968
3.531LeuThr: 3.531 ± 1.111
5.044LeuVal: 5.044 ± 0.902
1.261LeuTrp: 1.261 ± 0.38
4.035LeuTyr: 4.035 ± 0.924
0.0LeuXaa: 0.0 ± 0.0
Met
1.009MetAla: 1.009 ± 0.819
1.261MetCys: 1.261 ± 0.429
3.279MetAsp: 3.279 ± 0.488
1.009MetGlu: 1.009 ± 0.622
0.504MetPhe: 0.504 ± 0.251
1.261MetGly: 1.261 ± 0.563
0.0MetHis: 0.0 ± 0.0
3.279MetIle: 3.279 ± 0.538
2.774MetLys: 2.774 ± 0.986
2.018MetLeu: 2.018 ± 0.72
1.513MetMet: 1.513 ± 0.494
2.522MetAsn: 2.522 ± 0.651
1.261MetPro: 1.261 ± 0.716
1.513MetGln: 1.513 ± 0.807
4.54MetArg: 4.54 ± 1.09
3.783MetSer: 3.783 ± 1.456
2.522MetThr: 2.522 ± 0.491
2.018MetVal: 2.018 ± 0.935
0.0MetTrp: 0.0 ± 0.0
2.018MetTyr: 2.018 ± 0.594
0.0MetXaa: 0.0 ± 0.0
Asn
1.765AsnAla: 1.765 ± 0.718
1.009AsnCys: 1.009 ± 0.596
2.522AsnAsp: 2.522 ± 1.251
1.261AsnGlu: 1.261 ± 0.457
2.27AsnPhe: 2.27 ± 0.536
3.026AsnGly: 3.026 ± 1.368
0.757AsnHis: 0.757 ± 0.442
4.792AsnIle: 4.792 ± 0.801
3.279AsnLys: 3.279 ± 1.022
3.783AsnLeu: 3.783 ± 0.554
2.018AsnMet: 2.018 ± 0.782
1.513AsnAsn: 1.513 ± 0.609
4.288AsnPro: 4.288 ± 2.02
1.765AsnGln: 1.765 ± 0.624
1.513AsnArg: 1.513 ± 0.58
3.026AsnSer: 3.026 ± 0.195
3.279AsnThr: 3.279 ± 0.653
3.026AsnVal: 3.026 ± 0.467
0.252AsnTrp: 0.252 ± 0.322
1.261AsnTyr: 1.261 ± 0.508
0.0AsnXaa: 0.0 ± 0.0
Pro
3.026ProAla: 3.026 ± 1.733
0.757ProCys: 0.757 ± 0.258
4.54ProAsp: 4.54 ± 0.683
2.27ProGlu: 2.27 ± 0.678
0.757ProPhe: 0.757 ± 0.329
2.018ProGly: 2.018 ± 1.133
1.513ProHis: 1.513 ± 0.617
3.531ProIle: 3.531 ± 1.238
1.261ProLys: 1.261 ± 0.594
4.035ProLeu: 4.035 ± 1.166
1.765ProMet: 1.765 ± 0.763
2.27ProAsn: 2.27 ± 0.457
3.026ProPro: 3.026 ± 1.666
1.009ProGln: 1.009 ± 0.703
3.026ProArg: 3.026 ± 0.71
3.783ProSer: 3.783 ± 1.049
3.279ProThr: 3.279 ± 1.07
3.026ProVal: 3.026 ± 1.216
0.252ProTrp: 0.252 ± 0.322
2.774ProTyr: 2.774 ± 1.453
0.0ProXaa: 0.0 ± 0.0
Gln
1.513GlnAla: 1.513 ± 1.061
0.504GlnCys: 0.504 ± 0.251
2.522GlnAsp: 2.522 ± 1.019
2.018GlnGlu: 2.018 ± 0.867
0.757GlnPhe: 0.757 ± 0.329
1.765GlnGly: 1.765 ± 0.345
0.757GlnHis: 0.757 ± 0.332
2.522GlnIle: 2.522 ± 0.634
3.026GlnLys: 3.026 ± 1.503
1.513GlnLeu: 1.513 ± 0.923
0.757GlnMet: 0.757 ± 0.558
2.522GlnAsn: 2.522 ± 0.686
1.009GlnPro: 1.009 ± 0.609
1.513GlnGln: 1.513 ± 0.426
1.261GlnArg: 1.261 ± 0.477
3.531GlnSer: 3.531 ± 0.558
1.009GlnThr: 1.009 ± 0.496
2.27GlnVal: 2.27 ± 0.713
0.252GlnTrp: 0.252 ± 0.322
0.252GlnTyr: 0.252 ± 0.322
0.0GlnXaa: 0.0 ± 0.0
Arg
1.765ArgAla: 1.765 ± 0.592
0.504ArgCys: 0.504 ± 0.29
3.026ArgAsp: 3.026 ± 1.294
1.765ArgGlu: 1.765 ± 1.043
1.765ArgPhe: 1.765 ± 0.664
3.531ArgGly: 3.531 ± 0.69
0.757ArgHis: 0.757 ± 0.558
4.035ArgIle: 4.035 ± 0.871
3.531ArgLys: 3.531 ± 0.974
5.801ArgLeu: 5.801 ± 1.645
2.018ArgMet: 2.018 ± 0.721
2.018ArgAsn: 2.018 ± 0.337
2.522ArgPro: 2.522 ± 1.072
1.765ArgGln: 1.765 ± 0.839
3.783ArgArg: 3.783 ± 1.61
4.54ArgSer: 4.54 ± 0.624
3.026ArgThr: 3.026 ± 0.743
3.531ArgVal: 3.531 ± 0.548
0.0ArgTrp: 0.0 ± 0.0
2.018ArgTyr: 2.018 ± 0.982
0.0ArgXaa: 0.0 ± 0.0
Ser
4.035SerAla: 4.035 ± 1.176
1.009SerCys: 1.009 ± 0.339
7.062SerAsp: 7.062 ± 2.097
4.54SerGlu: 4.54 ± 1.036
4.54SerPhe: 4.54 ± 1.488
4.54SerGly: 4.54 ± 0.756
2.018SerHis: 2.018 ± 0.48
6.81SerIle: 6.81 ± 1.226
4.035SerLys: 4.035 ± 0.489
6.81SerLeu: 6.81 ± 0.894
1.765SerMet: 1.765 ± 0.861
3.279SerAsn: 3.279 ± 0.595
4.54SerPro: 4.54 ± 1.625
3.531SerGln: 3.531 ± 1.305
4.035SerArg: 4.035 ± 1.312
9.584SerSer: 9.584 ± 4.948
8.071SerThr: 8.071 ± 0.914
6.053SerVal: 6.053 ± 1.398
1.009SerTrp: 1.009 ± 0.427
4.54SerTyr: 4.54 ± 1.555
0.0SerXaa: 0.0 ± 0.0
Thr
3.531ThrAla: 3.531 ± 0.906
1.765ThrCys: 1.765 ± 0.739
3.026ThrAsp: 3.026 ± 0.988
2.522ThrGlu: 2.522 ± 1.035
1.765ThrPhe: 1.765 ± 0.626
3.279ThrGly: 3.279 ± 1.481
1.513ThrHis: 1.513 ± 0.449
6.305ThrIle: 6.305 ± 1.026
3.026ThrLys: 3.026 ± 0.863
5.296ThrLeu: 5.296 ± 0.944
3.026ThrMet: 3.026 ± 0.778
2.774ThrAsn: 2.774 ± 1.159
2.522ThrPro: 2.522 ± 0.842
1.261ThrGln: 1.261 ± 0.305
3.783ThrArg: 3.783 ± 1.026
6.053ThrSer: 6.053 ± 0.703
2.774ThrThr: 2.774 ± 1.764
3.531ThrVal: 3.531 ± 0.378
1.513ThrTrp: 1.513 ± 0.378
1.261ThrTyr: 1.261 ± 0.738
0.0ThrXaa: 0.0 ± 0.0
Val
2.774ValAla: 2.774 ± 0.809
0.504ValCys: 0.504 ± 0.298
4.035ValAsp: 4.035 ± 0.737
4.792ValGlu: 4.792 ± 1.322
3.026ValPhe: 3.026 ± 0.538
4.035ValGly: 4.035 ± 0.965
0.757ValHis: 0.757 ± 0.447
3.783ValIle: 3.783 ± 0.661
2.522ValLys: 2.522 ± 1.136
6.053ValLeu: 6.053 ± 1.404
2.27ValMet: 2.27 ± 0.536
2.774ValAsn: 2.774 ± 1.183
2.27ValPro: 2.27 ± 0.605
2.774ValGln: 2.774 ± 0.924
3.026ValArg: 3.026 ± 1.001
6.81ValSer: 6.81 ± 1.238
2.774ValThr: 2.774 ± 0.55
3.783ValVal: 3.783 ± 0.801
0.252ValTrp: 0.252 ± 0.149
3.026ValTyr: 3.026 ± 1.106
0.0ValXaa: 0.0 ± 0.0
Trp
1.261TrpAla: 1.261 ± 0.745
0.0TrpCys: 0.0 ± 0.0
0.252TrpAsp: 0.252 ± 0.281
1.261TrpGlu: 1.261 ± 0.455
0.252TrpPhe: 0.252 ± 0.322
1.261TrpGly: 1.261 ± 0.429
0.504TrpHis: 0.504 ± 0.458
0.0TrpIle: 0.0 ± 0.0
0.504TrpLys: 0.504 ± 0.454
0.504TrpLeu: 0.504 ± 0.251
0.504TrpMet: 0.504 ± 0.381
1.009TrpAsn: 1.009 ± 0.502
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.504TrpArg: 0.504 ± 0.251
0.252TrpSer: 0.252 ± 0.322
1.513TrpThr: 1.513 ± 0.612
1.009TrpVal: 1.009 ± 0.339
0.252TrpTrp: 0.252 ± 0.322
0.757TrpTyr: 0.757 ± 0.402
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.522TyrAla: 2.522 ± 1.015
0.757TyrCys: 0.757 ± 0.558
2.774TyrAsp: 2.774 ± 0.813
3.279TyrGlu: 3.279 ± 0.866
1.513TyrPhe: 1.513 ± 0.426
1.261TyrGly: 1.261 ± 0.444
1.765TyrHis: 1.765 ± 0.542
3.279TyrIle: 3.279 ± 0.375
1.765TyrLys: 1.765 ± 0.394
3.279TyrLeu: 3.279 ± 0.647
1.009TyrMet: 1.009 ± 0.295
1.765TyrAsn: 1.765 ± 0.626
2.018TyrPro: 2.018 ± 0.484
1.009TyrGln: 1.009 ± 0.633
1.009TyrArg: 1.009 ± 0.399
4.288TyrSer: 4.288 ± 1.9
1.765TyrThr: 1.765 ± 0.791
2.522TyrVal: 2.522 ± 0.334
0.252TyrTrp: 0.252 ± 0.322
1.009TyrTyr: 1.009 ± 1.122
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (3966 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski