Amino acid dipepetide frequency for Pseudobacteriovorax antillogorgiicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.704AlaAla: 5.704 ± 0.071	1.012AlaCys: 1.012 ± 0.023	3.84AlaAsp: 3.84 ± 0.048	4.536AlaGlu: 4.536 ± 0.053	3.227AlaPhe: 3.227 ± 0.042	4.733AlaGly: 4.733 ± 0.062	1.435AlaHis: 1.435 ± 0.03	5.199AlaIle: 5.199 ± 0.055	4.606AlaLys: 4.606 ± 0.068	7.686AlaLeu: 7.686 ± 0.073	2.01AlaMet: 2.01 ± 0.03	2.86AlaAsn: 2.86 ± 0.042	2.607AlaPro: 2.607 ± 0.041	2.859AlaGln: 2.859 ± 0.049	3.55AlaArg: 3.55 ± 0.041	5.711AlaSer: 5.711 ± 0.062	3.5AlaThr: 3.5 ± 0.04	4.516AlaVal: 4.516 ± 0.049	0.904AlaTrp: 0.904 ± 0.022	2.313AlaTyr: 2.313 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	0.67CysAla: 0.67 ± 0.019	0.132CysCys: 0.132 ± 0.011	0.662CysAsp: 0.662 ± 0.019	0.692CysGlu: 0.692 ± 0.021	0.592CysPhe: 0.592 ± 0.016	0.87CysGly: 0.87 ± 0.021	0.413CysHis: 0.413 ± 0.022	0.559CysIle: 0.559 ± 0.016	0.507CysLys: 0.507 ± 0.017	1.251CysLeu: 1.251 ± 0.025	0.21CysMet: 0.21 ± 0.009	0.399CysAsn: 0.399 ± 0.015	0.519CysPro: 0.519 ± 0.017	0.634CysGln: 0.634 ± 0.016	0.621CysArg: 0.621 ± 0.02	0.902CysSer: 0.902 ± 0.022	0.516CysThr: 0.516 ± 0.016	0.574CysVal: 0.574 ± 0.017	0.115CysTrp: 0.115 ± 0.008	0.363CysTyr: 0.363 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.684AspAla: 3.684 ± 0.051	0.635AspCys: 0.635 ± 0.022	3.789AspAsp: 3.789 ± 0.07	4.088AspGlu: 4.088 ± 0.05	2.964AspPhe: 2.964 ± 0.043	4.288AspGly: 4.288 ± 0.057	1.596AspHis: 1.596 ± 0.032	3.977AspIle: 3.977 ± 0.046	2.853AspLys: 2.853 ± 0.036	6.675AspLeu: 6.675 ± 0.055	1.173AspMet: 1.173 ± 0.022	1.973AspAsn: 1.973 ± 0.032	2.792AspPro: 2.792 ± 0.039	3.104AspGln: 3.104 ± 0.04	3.471AspArg: 3.471 ± 0.041	4.137AspSer: 4.137 ± 0.052	2.485AspThr: 2.485 ± 0.04	3.442AspVal: 3.442 ± 0.041	0.789AspTrp: 0.789 ± 0.022	2.15AspTyr: 2.15 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	5.34GluAla: 5.34 ± 0.053	0.522GluCys: 0.522 ± 0.017	3.776GluAsp: 3.776 ± 0.049	4.333GluGlu: 4.333 ± 0.053	2.688GluPhe: 2.688 ± 0.039	4.119GluGly: 4.119 ± 0.05	1.195GluHis: 1.195 ± 0.023	4.435GluIle: 4.435 ± 0.055	4.019GluLys: 4.019 ± 0.056	6.569GluLeu: 6.569 ± 0.059	1.348GluMet: 1.348 ± 0.026	2.762GluAsn: 2.762 ± 0.034	2.33GluPro: 2.33 ± 0.034	2.891GluGln: 2.891 ± 0.042	3.435GluArg: 3.435 ± 0.046	5.037GluSer: 5.037 ± 0.051	3.613GluThr: 3.613 ± 0.038	4.149GluVal: 4.149 ± 0.047	0.682GluTrp: 0.682 ± 0.018	1.794GluTyr: 1.794 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	3.267PheAla: 3.267 ± 0.04	0.575PheCys: 0.575 ± 0.015	3.053PheAsp: 3.053 ± 0.044	3.02PheGlu: 3.02 ± 0.044	2.146PhePhe: 2.146 ± 0.036	3.191PheGly: 3.191 ± 0.045	1.077PheHis: 1.077 ± 0.022	2.563PheIle: 2.563 ± 0.039	2.452PheLys: 2.452 ± 0.035	4.591PheLeu: 4.591 ± 0.055	0.963PheMet: 0.963 ± 0.023	1.819PheAsn: 1.819 ± 0.035	1.704PhePro: 1.704 ± 0.029	1.967PheGln: 1.967 ± 0.034	2.272PheArg: 2.272 ± 0.03	3.769PheSer: 3.769 ± 0.043	2.224PheThr: 2.224 ± 0.034	2.791PheVal: 2.791 ± 0.038	0.579PheTrp: 0.579 ± 0.016	1.54PheTyr: 1.54 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	4.766GlyAla: 4.766 ± 0.051	0.775GlyCys: 0.775 ± 0.02	4.058GlyAsp: 4.058 ± 0.059	4.062GlyGlu: 4.062 ± 0.05	3.6GlyPhe: 3.6 ± 0.044	4.534GlyGly: 4.534 ± 0.066	1.458GlyHis: 1.458 ± 0.029	4.61GlyIle: 4.61 ± 0.047	3.947GlyLys: 3.947 ± 0.05	7.106GlyLeu: 7.106 ± 0.07	1.643GlyMet: 1.643 ± 0.028	2.58GlyAsn: 2.58 ± 0.04	2.255GlyPro: 2.255 ± 0.08	2.957GlyGln: 2.957 ± 0.042	3.488GlyArg: 3.488 ± 0.044	5.047GlySer: 5.047 ± 0.045	3.498GlyThr: 3.498 ± 0.04	4.624GlyVal: 4.624 ± 0.057	0.814GlyTrp: 0.814 ± 0.023	2.3GlyTyr: 2.3 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	1.112HisAla: 1.112 ± 0.026	0.325HisCys: 0.325 ± 0.012	1.193HisAsp: 1.193 ± 0.026	1.331HisGlu: 1.331 ± 0.026	1.021HisPhe: 1.021 ± 0.025	1.666HisGly: 1.666 ± 0.029	0.724HisHis: 0.724 ± 0.021	1.353HisIle: 1.353 ± 0.024	1.048HisLys: 1.048 ± 0.025	2.312HisLeu: 2.312 ± 0.03	0.47HisMet: 0.47 ± 0.014	0.752HisAsn: 0.752 ± 0.02	1.125HisPro: 1.125 ± 0.027	1.115HisGln: 1.115 ± 0.022	1.339HisArg: 1.339 ± 0.025	1.519HisSer: 1.519 ± 0.033	0.885HisThr: 0.885 ± 0.023	1.224HisVal: 1.224 ± 0.024	0.363HisTrp: 0.363 ± 0.012	0.8HisTyr: 0.8 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.205IleAla: 5.205 ± 0.052	0.779IleCys: 0.779 ± 0.02	4.508IleAsp: 4.508 ± 0.046	4.741IleGlu: 4.741 ± 0.053	2.757IlePhe: 2.757 ± 0.041	4.168IleGly: 4.168 ± 0.045	1.467IleHis: 1.467 ± 0.027	3.475IleIle: 3.475 ± 0.041	3.63IleLys: 3.63 ± 0.041	6.293IleLeu: 6.293 ± 0.07	1.188IleMet: 1.188 ± 0.026	2.649IleAsn: 2.649 ± 0.04	2.933IlePro: 2.933 ± 0.035	2.562IleGln: 2.562 ± 0.036	3.407IleArg: 3.407 ± 0.038	4.959IleSer: 4.959 ± 0.051	3.021IleThr: 3.021 ± 0.036	3.871IleVal: 3.871 ± 0.045	0.651IleTrp: 0.651 ± 0.017	1.979IleTyr: 1.979 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.763LysAla: 4.763 ± 0.061	0.371LysCys: 0.371 ± 0.012	3.56LysAsp: 3.56 ± 0.039	3.656LysGlu: 3.656 ± 0.046	2.086LysPhe: 2.086 ± 0.037	3.687LysGly: 3.687 ± 0.061	1.126LysHis: 1.126 ± 0.026	4.0LysIle: 4.0 ± 0.045	4.242LysLys: 4.242 ± 0.091	5.714LysLeu: 5.714 ± 0.051	1.202LysMet: 1.202 ± 0.025	2.532LysAsn: 2.532 ± 0.043	2.57LysPro: 2.57 ± 0.039	2.312LysGln: 2.312 ± 0.041	2.994LysArg: 2.994 ± 0.041	4.214LysSer: 4.214 ± 0.043	3.171LysThr: 3.171 ± 0.048	4.147LysVal: 4.147 ± 0.045	0.501LysTrp: 0.501 ± 0.016	1.568LysTyr: 1.568 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	8.617LeuAla: 8.617 ± 0.084	1.115LeuCys: 1.115 ± 0.024	6.366LeuAsp: 6.366 ± 0.056	7.113LeuGlu: 7.113 ± 0.07	4.146LeuPhe: 4.146 ± 0.048	7.67LeuGly: 7.67 ± 0.062	1.885LeuHis: 1.885 ± 0.029	5.988LeuIle: 5.988 ± 0.054	6.697LeuLys: 6.697 ± 0.066	9.325LeuLeu: 9.325 ± 0.086	2.265LeuMet: 2.265 ± 0.033	4.242LeuAsn: 4.242 ± 0.041	4.19LeuPro: 4.19 ± 0.047	3.776LeuGln: 3.776 ± 0.044	5.089LeuArg: 5.089 ± 0.053	8.802LeuSer: 8.802 ± 0.08	4.928LeuThr: 4.928 ± 0.052	6.621LeuVal: 6.621 ± 0.063	1.145LeuTrp: 1.145 ± 0.026	2.73LeuTyr: 2.73 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	1.976MetAla: 1.976 ± 0.033	0.157MetCys: 0.157 ± 0.009	1.172MetAsp: 1.172 ± 0.024	1.334MetGlu: 1.334 ± 0.026	0.778MetPhe: 0.778 ± 0.02	1.549MetGly: 1.549 ± 0.029	0.324MetHis: 0.324 ± 0.014	1.683MetIle: 1.683 ± 0.029	1.752MetLys: 1.752 ± 0.029	1.87MetLeu: 1.87 ± 0.03	0.6MetMet: 0.6 ± 0.021	1.05MetAsn: 1.05 ± 0.022	0.889MetPro: 0.889 ± 0.02	0.707MetGln: 0.707 ± 0.019	1.066MetArg: 1.066 ± 0.024	1.754MetSer: 1.754 ± 0.027	1.423MetThr: 1.423 ± 0.025	1.517MetVal: 1.517 ± 0.025	0.171MetTrp: 0.171 ± 0.009	0.398MetTyr: 0.398 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.368AsnAla: 2.368 ± 0.036	0.501AsnCys: 0.501 ± 0.017	2.194AsnAsp: 2.194 ± 0.036	2.212AsnGlu: 2.212 ± 0.032	1.919AsnPhe: 1.919 ± 0.032	2.685AsnGly: 2.685 ± 0.038	1.035AsnHis: 1.035 ± 0.021	2.531AsnIle: 2.531 ± 0.035	1.799AsnLys: 1.799 ± 0.029	4.621AsnLeu: 4.621 ± 0.048	0.842AsnMet: 0.842 ± 0.018	1.524AsnAsn: 1.524 ± 0.034	2.236AsnPro: 2.236 ± 0.037	2.19AsnGln: 2.19 ± 0.039	2.416AsnArg: 2.416 ± 0.036	2.759AsnSer: 2.759 ± 0.046	1.771AsnThr: 1.771 ± 0.028	2.114AsnVal: 2.114 ± 0.033	0.522AsnTrp: 0.522 ± 0.016	1.465AsnTyr: 1.465 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	2.557ProAla: 2.557 ± 0.036	0.403ProCys: 0.403 ± 0.014	2.516ProAsp: 2.516 ± 0.04	3.224ProGlu: 3.224 ± 0.044	1.842ProPhe: 1.842 ± 0.031	2.696ProGly: 2.696 ± 0.039	0.898ProHis: 0.898 ± 0.022	2.634ProIle: 2.634 ± 0.034	2.603ProLys: 2.603 ± 0.041	3.795ProLeu: 3.795 ± 0.047	0.98ProMet: 0.98 ± 0.024	1.63ProAsn: 1.63 ± 0.032	1.497ProPro: 1.497 ± 0.034	1.77ProGln: 1.77 ± 0.03	1.823ProArg: 1.823 ± 0.03	3.23ProSer: 3.23 ± 0.043	1.919ProThr: 1.919 ± 0.03	2.59ProVal: 2.59 ± 0.036	0.629ProTrp: 0.629 ± 0.018	1.324ProTyr: 1.324 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.639GlnAla: 3.639 ± 0.041	0.396GlnCys: 0.396 ± 0.013	2.744GlnAsp: 2.744 ± 0.039	3.2GlnGlu: 3.2 ± 0.05	1.719GlnPhe: 1.719 ± 0.032	3.277GlnGly: 3.277 ± 0.046	0.747GlnHis: 0.747 ± 0.02	2.642GlnIle: 2.642 ± 0.036	2.723GlnLys: 2.723 ± 0.043	4.166GlnLeu: 4.166 ± 0.052	0.899GlnMet: 0.899 ± 0.019	1.737GlnAsn: 1.737 ± 0.029	1.358GlnPro: 1.358 ± 0.025	1.829GlnGln: 1.829 ± 0.053	2.138GlnArg: 2.138 ± 0.036	3.29GlnSer: 3.29 ± 0.042	2.057GlnThr: 2.057 ± 0.036	3.021GlnVal: 3.021 ± 0.045	0.604GlnTrp: 0.604 ± 0.018	1.162GlnTyr: 1.162 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	3.228ArgAla: 3.228 ± 0.04	0.575ArgCys: 0.575 ± 0.018	3.209ArgAsp: 3.209 ± 0.043	3.167ArgGlu: 3.167 ± 0.044	2.76ArgPhe: 2.76 ± 0.034	2.984ArgGly: 2.984 ± 0.04	1.136ArgHis: 1.136 ± 0.021	3.438ArgIle: 3.438 ± 0.042	3.089ArgLys: 3.089 ± 0.038	5.589ArgLeu: 5.589 ± 0.053	1.16ArgMet: 1.16 ± 0.023	2.169ArgAsn: 2.169 ± 0.034	1.836ArgPro: 1.836 ± 0.029	2.279ArgGln: 2.279 ± 0.037	2.841ArgArg: 2.841 ± 0.044	3.901ArgSer: 3.901 ± 0.045	2.353ArgThr: 2.353 ± 0.035	3.299ArgVal: 3.299 ± 0.039	0.756ArgTrp: 0.756 ± 0.019	2.078ArgTyr: 2.078 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	4.773SerAla: 4.773 ± 0.054	1.14SerCys: 1.14 ± 0.027	4.265SerAsp: 4.265 ± 0.052	4.626SerGlu: 4.626 ± 0.057	4.024SerPhe: 4.024 ± 0.047	5.197SerGly: 5.197 ± 0.051	1.829SerHis: 1.829 ± 0.031	5.065SerIle: 5.065 ± 0.05	4.139SerLys: 4.139 ± 0.046	8.796SerLeu: 8.796 ± 0.076	1.826SerMet: 1.826 ± 0.032	2.956SerAsn: 2.956 ± 0.045	3.155SerPro: 3.155 ± 0.04	3.705SerGln: 3.705 ± 0.046	3.852SerArg: 3.852 ± 0.041	6.272SerSer: 6.272 ± 0.068	3.332SerThr: 3.332 ± 0.045	4.295SerVal: 4.295 ± 0.048	1.073SerTrp: 1.073 ± 0.024	2.869SerTyr: 2.869 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	3.529ThrAla: 3.529 ± 0.047	0.589ThrCys: 0.589 ± 0.017	2.556ThrAsp: 2.556 ± 0.038	2.788ThrGlu: 2.788 ± 0.034	2.224ThrPhe: 2.224 ± 0.037	3.495ThrGly: 3.495 ± 0.044	0.989ThrHis: 0.989 ± 0.02	3.609ThrIle: 3.609 ± 0.039	2.653ThrLys: 2.653 ± 0.037	5.245ThrLeu: 5.245 ± 0.049	1.128ThrMet: 1.128 ± 0.023	1.85ThrAsn: 1.85 ± 0.028	2.346ThrPro: 2.346 ± 0.04	1.795ThrGln: 1.795 ± 0.031	2.161ThrArg: 2.161 ± 0.032	3.577ThrSer: 3.577 ± 0.043	2.417ThrThr: 2.417 ± 0.038	3.256ThrVal: 3.256 ± 0.04	0.649ThrTrp: 0.649 ± 0.019	1.567ThrTyr: 1.567 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	5.108ValAla: 5.108 ± 0.052	0.681ValCys: 0.681 ± 0.018	3.986ValAsp: 3.986 ± 0.047	4.25ValGlu: 4.25 ± 0.043	2.896ValPhe: 2.896 ± 0.039	4.17ValGly: 4.17 ± 0.054	1.217ValHis: 1.217 ± 0.025	4.044ValIle: 4.044 ± 0.045	3.488ValLys: 3.488 ± 0.04	6.089ValLeu: 6.089 ± 0.055	1.39ValMet: 1.39 ± 0.027	2.451ValAsn: 2.451 ± 0.04	2.496ValPro: 2.496 ± 0.033	2.202ValGln: 2.202 ± 0.034	3.063ValArg: 3.063 ± 0.041	5.074ValSer: 5.074 ± 0.055	3.262ValThr: 3.262 ± 0.037	4.285ValVal: 4.285 ± 0.059	0.711ValTrp: 0.711 ± 0.018	1.879ValTyr: 1.879 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	0.803TrpAla: 0.803 ± 0.02	0.121TrpCys: 0.121 ± 0.008	0.754TrpAsp: 0.754 ± 0.022	0.663TrpGlu: 0.663 ± 0.017	0.53TrpPhe: 0.53 ± 0.016	0.853TrpGly: 0.853 ± 0.027	0.288TrpHis: 0.288 ± 0.012	0.718TrpIle: 0.718 ± 0.02	0.591TrpLys: 0.591 ± 0.018	1.416TrpLeu: 1.416 ± 0.029	0.272TrpMet: 0.272 ± 0.011	0.567TrpAsn: 0.567 ± 0.016	0.426TrpPro: 0.426 ± 0.012	0.865TrpGln: 0.865 ± 0.02	0.642TrpArg: 0.642 ± 0.018	0.918TrpSer: 0.918 ± 0.023	0.601TrpThr: 0.601 ± 0.016	0.734TrpVal: 0.734 ± 0.016	0.164TrpTrp: 0.164 ± 0.01	0.375TrpTyr: 0.375 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.699TyrAla: 1.699 ± 0.029	0.401TyrCys: 0.401 ± 0.013	1.865TyrAsp: 1.865 ± 0.035	2.0TyrGlu: 2.0 ± 0.031	1.644TyrPhe: 1.644 ± 0.032	2.291TyrGly: 2.291 ± 0.033	0.836TyrHis: 0.836 ± 0.021	1.719TyrIle: 1.719 ± 0.029	1.579TyrLys: 1.579 ± 0.029	3.602TyrLeu: 3.602 ± 0.048	0.602TyrMet: 0.602 ± 0.019	1.2TyrAsn: 1.2 ± 0.027	1.297TyrPro: 1.297 ± 0.027	1.829TyrGln: 1.829 ± 0.032	2.179TyrArg: 2.179 ± 0.031	2.315TyrSer: 2.315 ± 0.032	1.447TyrThr: 1.447 ± 0.03	1.669TyrVal: 1.669 ± 0.026	0.481TyrTrp: 0.481 ± 0.016	1.221TyrTyr: 1.221 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6344 proteins (2143815 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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