Amino acid dipepetide frequency for Paraburkholderia lycopersici

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.962AlaAla: 18.962 ± 0.14	1.447AlaCys: 1.447 ± 0.03	6.591AlaAsp: 6.591 ± 0.065	5.971AlaGlu: 5.971 ± 0.073	4.569AlaPhe: 4.569 ± 0.049	11.018AlaGly: 11.018 ± 0.094	3.17AlaHis: 3.17 ± 0.044	5.796AlaIle: 5.796 ± 0.057	3.569AlaLys: 3.569 ± 0.055	15.073AlaLeu: 15.073 ± 0.121	3.265AlaMet: 3.265 ± 0.038	3.449AlaAsn: 3.449 ± 0.043	6.398AlaPro: 6.398 ± 0.075	5.909AlaGln: 5.909 ± 0.066	10.358AlaArg: 10.358 ± 0.097	7.701AlaSer: 7.701 ± 0.081	6.391AlaThr: 6.391 ± 0.069	8.834AlaVal: 8.834 ± 0.07	1.888AlaTrp: 1.888 ± 0.038	2.691AlaTyr: 2.691 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.389CysAla: 1.389 ± 0.03	0.142CysCys: 0.142 ± 0.009	0.552CysAsp: 0.552 ± 0.015	0.572CysGlu: 0.572 ± 0.018	0.334CysPhe: 0.334 ± 0.013	1.035CysGly: 1.035 ± 0.025	0.256CysHis: 0.256 ± 0.012	0.397CysIle: 0.397 ± 0.015	0.221CysLys: 0.221 ± 0.012	0.823CysLeu: 0.823 ± 0.024	0.212CysMet: 0.212 ± 0.009	0.242CysAsn: 0.242 ± 0.01	0.474CysPro: 0.474 ± 0.017	0.214CysGln: 0.214 ± 0.011	0.656CysArg: 0.656 ± 0.019	0.526CysSer: 0.526 ± 0.015	0.481CysThr: 0.481 ± 0.017	0.821CysVal: 0.821 ± 0.02	0.135CysTrp: 0.135 ± 0.009	0.226CysTyr: 0.226 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.873AspAla: 7.873 ± 0.069	0.495AspCys: 0.495 ± 0.016	3.084AspAsp: 3.084 ± 0.047	3.466AspGlu: 3.466 ± 0.049	1.97AspPhe: 1.97 ± 0.029	4.446AspGly: 4.446 ± 0.043	1.119AspHis: 1.119 ± 0.023	2.452AspIle: 2.452 ± 0.032	1.336AspLys: 1.336 ± 0.031	5.143AspLeu: 5.143 ± 0.047	1.157AspMet: 1.157 ± 0.023	1.241AspAsn: 1.241 ± 0.027	2.888AspPro: 2.888 ± 0.034	1.5AspGln: 1.5 ± 0.027	3.256AspArg: 3.256 ± 0.039	2.427AspSer: 2.427 ± 0.044	2.663AspThr: 2.663 ± 0.04	4.353AspVal: 4.353 ± 0.05	0.897AspTrp: 0.897 ± 0.023	1.531AspTyr: 1.531 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	7.289GluAla: 7.289 ± 0.067	0.43GluCys: 0.43 ± 0.014	2.196GluAsp: 2.196 ± 0.034	2.463GluGlu: 2.463 ± 0.036	1.716GluPhe: 1.716 ± 0.028	3.639GluGly: 3.639 ± 0.05	1.451GluHis: 1.451 ± 0.027	2.776GluIle: 2.776 ± 0.039	1.747GluLys: 1.747 ± 0.039	5.328GluLeu: 5.328 ± 0.055	1.231GluMet: 1.231 ± 0.026	1.413GluAsn: 1.413 ± 0.026	2.695GluPro: 2.695 ± 0.034	2.261GluGln: 2.261 ± 0.04	5.124GluArg: 5.124 ± 0.064	2.669GluSer: 2.669 ± 0.04	2.969GluThr: 2.969 ± 0.044	3.496GluVal: 3.496 ± 0.048	0.714GluTrp: 0.714 ± 0.017	1.147GluTyr: 1.147 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.892PheAla: 4.892 ± 0.055	0.431PheCys: 0.431 ± 0.014	2.548PheAsp: 2.548 ± 0.037	2.169PheGlu: 2.169 ± 0.035	1.392PhePhe: 1.392 ± 0.032	3.691PheGly: 3.691 ± 0.049	0.779PheHis: 0.779 ± 0.02	1.494PheIle: 1.494 ± 0.028	0.868PheLys: 0.868 ± 0.02	2.994PheLeu: 2.994 ± 0.043	0.783PheMet: 0.783 ± 0.019	1.067PheAsn: 1.067 ± 0.021	1.538PhePro: 1.538 ± 0.033	0.963PheGln: 0.963 ± 0.022	2.141PheArg: 2.141 ± 0.033	2.245PheSer: 2.245 ± 0.033	1.942PheThr: 1.942 ± 0.034	3.239PheVal: 3.239 ± 0.047	0.501PheTrp: 0.501 ± 0.017	0.943PheTyr: 0.943 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	10.403GlyAla: 10.403 ± 0.082	0.85GlyCys: 0.85 ± 0.019	3.942GlyAsp: 3.942 ± 0.046	4.672GlyGlu: 4.672 ± 0.051	3.411GlyPhe: 3.411 ± 0.049	6.91GlyGly: 6.91 ± 0.08	1.95GlyHis: 1.95 ± 0.033	4.125GlyIle: 4.125 ± 0.052	3.134GlyLys: 3.134 ± 0.041	7.84GlyLeu: 7.84 ± 0.07	2.179GlyMet: 2.179 ± 0.034	2.426GlyAsn: 2.426 ± 0.045	3.006GlyPro: 3.006 ± 0.037	2.701GlyGln: 2.701 ± 0.041	5.466GlyArg: 5.466 ± 0.057	4.4GlySer: 4.4 ± 0.056	4.654GlyThr: 4.654 ± 0.079	6.809GlyVal: 6.809 ± 0.072	1.332GlyTrp: 1.332 ± 0.027	2.458GlyTyr: 2.458 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	3.375HisAla: 3.375 ± 0.042	0.263HisCys: 0.263 ± 0.012	1.403HisAsp: 1.403 ± 0.031	1.313HisGlu: 1.313 ± 0.029	0.956HisPhe: 0.956 ± 0.021	2.243HisGly: 2.243 ± 0.039	0.63HisHis: 0.63 ± 0.02	0.895HisIle: 0.895 ± 0.022	0.518HisLys: 0.518 ± 0.018	2.182HisLeu: 2.182 ± 0.037	0.53HisMet: 0.53 ± 0.018	0.534HisAsn: 0.534 ± 0.016	1.398HisPro: 1.398 ± 0.029	0.607HisGln: 0.607 ± 0.017	1.561HisArg: 1.561 ± 0.027	1.061HisSer: 1.061 ± 0.027	1.108HisThr: 1.108 ± 0.021	1.81HisVal: 1.81 ± 0.033	0.417HisTrp: 0.417 ± 0.015	0.666HisTyr: 0.666 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.861IleAla: 6.861 ± 0.065	0.432IleCys: 0.432 ± 0.014	3.365IleAsp: 3.365 ± 0.046	3.277IleGlu: 3.277 ± 0.047	1.433IlePhe: 1.433 ± 0.029	4.613IleGly: 4.613 ± 0.047	0.859IleHis: 0.859 ± 0.023	1.417IleIle: 1.417 ± 0.028	1.201IleLys: 1.201 ± 0.027	3.223IleLeu: 3.223 ± 0.043	0.723IleMet: 0.723 ± 0.019	1.235IleAsn: 1.235 ± 0.028	1.951IlePro: 1.951 ± 0.034	1.157IleGln: 1.157 ± 0.025	2.73IleArg: 2.73 ± 0.036	2.362IleSer: 2.362 ± 0.035	2.218IleThr: 2.218 ± 0.035	4.329IleVal: 4.329 ± 0.049	0.512IleTrp: 0.512 ± 0.018	1.047IleTyr: 1.047 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.443LysAla: 3.443 ± 0.061	0.168LysCys: 0.168 ± 0.01	1.366LysAsp: 1.366 ± 0.029	1.328LysGlu: 1.328 ± 0.029	0.833LysPhe: 0.833 ± 0.022	2.041LysGly: 2.041 ± 0.034	0.663LysHis: 0.663 ± 0.02	1.491LysIle: 1.491 ± 0.027	1.135LysLys: 1.135 ± 0.034	3.19LysLeu: 3.19 ± 0.042	0.718LysMet: 0.718 ± 0.018	0.798LysAsn: 0.798 ± 0.023	1.903LysPro: 1.903 ± 0.036	1.116LysGln: 1.116 ± 0.027	2.297LysArg: 2.297 ± 0.039	1.626LysSer: 1.626 ± 0.032	1.75LysThr: 1.75 ± 0.032	2.136LysVal: 2.136 ± 0.04	0.354LysTrp: 0.354 ± 0.014	0.665LysTyr: 0.665 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.858LeuAla: 14.858 ± 0.107	1.088LeuCys: 1.088 ± 0.023	6.092LeuAsp: 6.092 ± 0.061	5.143LeuGlu: 5.143 ± 0.06	3.649LeuPhe: 3.649 ± 0.053	8.068LeuGly: 8.068 ± 0.073	2.304LeuHis: 2.304 ± 0.033	4.396LeuIle: 4.396 ± 0.048	3.113LeuLys: 3.113 ± 0.043	9.869LeuLeu: 9.869 ± 0.095	2.239LeuMet: 2.239 ± 0.032	2.696LeuAsn: 2.696 ± 0.041	5.718LeuPro: 5.718 ± 0.059	3.197LeuGln: 3.197 ± 0.046	7.445LeuArg: 7.445 ± 0.076	5.858LeuSer: 5.858 ± 0.053	5.284LeuThr: 5.284 ± 0.058	7.664LeuVal: 7.664 ± 0.065	1.126LeuTrp: 1.126 ± 0.027	2.234LeuTyr: 2.234 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.506MetAla: 2.506 ± 0.037	0.186MetCys: 0.186 ± 0.008	0.946MetAsp: 0.946 ± 0.023	0.912MetGlu: 0.912 ± 0.02	0.751MetPhe: 0.751 ± 0.019	1.554MetGly: 1.554 ± 0.032	0.54MetHis: 0.54 ± 0.017	1.059MetIle: 1.059 ± 0.024	0.967MetLys: 0.967 ± 0.025	2.62MetLeu: 2.62 ± 0.036	0.557MetMet: 0.557 ± 0.017	0.936MetAsn: 0.936 ± 0.022	1.5MetPro: 1.5 ± 0.034	0.989MetGln: 0.989 ± 0.023	1.816MetArg: 1.816 ± 0.033	1.717MetSer: 1.717 ± 0.031	1.522MetThr: 1.522 ± 0.031	1.395MetVal: 1.395 ± 0.025	0.208MetTrp: 0.208 ± 0.01	0.399MetTyr: 0.399 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.794AsnAla: 3.794 ± 0.05	0.253AsnCys: 0.253 ± 0.01	1.454AsnAsp: 1.454 ± 0.026	1.382AsnGlu: 1.382 ± 0.027	0.961AsnPhe: 0.961 ± 0.021	2.665AsnGly: 2.665 ± 0.047	0.541AsnHis: 0.541 ± 0.015	1.145AsnIle: 1.145 ± 0.026	0.605AsnLys: 0.605 ± 0.022	2.697AsnLeu: 2.697 ± 0.039	0.568AsnMet: 0.568 ± 0.017	0.793AsnAsn: 0.793 ± 0.028	1.768AsnPro: 1.768 ± 0.03	0.901AsnGln: 0.901 ± 0.02	1.806AsnArg: 1.806 ± 0.031	1.262AsnSer: 1.262 ± 0.035	1.397AsnThr: 1.397 ± 0.032	2.319AsnVal: 2.319 ± 0.042	0.425AsnTrp: 0.425 ± 0.016	0.688AsnTyr: 0.688 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	6.942ProAla: 6.942 ± 0.078	0.378ProCys: 0.378 ± 0.014	3.25ProAsp: 3.25 ± 0.039	3.074ProGlu: 3.074 ± 0.045	1.917ProPhe: 1.917 ± 0.029	4.569ProGly: 4.569 ± 0.049	1.3ProHis: 1.3 ± 0.031	1.808ProIle: 1.808 ± 0.029	1.309ProLys: 1.309 ± 0.028	5.246ProLeu: 5.246 ± 0.057	1.074ProMet: 1.074 ± 0.025	1.338ProAsn: 1.338 ± 0.026	2.579ProPro: 2.579 ± 0.053	1.994ProGln: 1.994 ± 0.033	3.182ProArg: 3.182 ± 0.051	2.616ProSer: 2.616 ± 0.039	2.37ProThr: 2.37 ± 0.034	4.389ProVal: 4.389 ± 0.052	0.719ProTrp: 0.719 ± 0.02	1.215ProTyr: 1.215 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.448GlnAla: 4.448 ± 0.054	0.295GlnCys: 0.295 ± 0.011	1.36GlnAsp: 1.36 ± 0.026	1.302GlnGlu: 1.302 ± 0.026	1.283GlnPhe: 1.283 ± 0.026	2.471GlnGly: 2.471 ± 0.036	0.94GlnHis: 0.94 ± 0.023	1.927GlnIle: 1.927 ± 0.029	1.086GlnLys: 1.086 ± 0.024	3.69GlnLeu: 3.69 ± 0.051	0.989GlnMet: 0.989 ± 0.019	0.965GlnAsn: 0.965 ± 0.024	2.012GlnPro: 2.012 ± 0.034	1.803GlnGln: 1.803 ± 0.038	2.987GlnArg: 2.987 ± 0.042	2.0GlnSer: 2.0 ± 0.037	2.032GlnThr: 2.032 ± 0.033	2.402GlnVal: 2.402 ± 0.036	0.568GlnTrp: 0.568 ± 0.017	0.951GlnTyr: 0.951 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	9.225ArgAla: 9.225 ± 0.09	0.661ArgCys: 0.661 ± 0.02	3.966ArgAsp: 3.966 ± 0.048	4.862ArgGlu: 4.862 ± 0.057	3.014ArgPhe: 3.014 ± 0.04	4.906ArgGly: 4.906 ± 0.048	2.01ArgHis: 2.01 ± 0.04	3.594ArgIle: 3.594 ± 0.045	2.136ArgLys: 2.136 ± 0.033	7.477ArgLeu: 7.477 ± 0.076	1.875ArgMet: 1.875 ± 0.03	1.965ArgAsn: 1.965 ± 0.027	3.173ArgPro: 3.173 ± 0.041	2.493ArgGln: 2.493 ± 0.035	5.791ArgArg: 5.791 ± 0.072	3.545ArgSer: 3.545 ± 0.045	3.529ArgThr: 3.529 ± 0.039	5.503ArgVal: 5.503 ± 0.06	1.086ArgTrp: 1.086 ± 0.023	2.1ArgTyr: 2.1 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.905SerAla: 6.905 ± 0.076	0.456SerCys: 0.456 ± 0.015	2.643SerAsp: 2.643 ± 0.04	2.56SerGlu: 2.56 ± 0.045	2.074SerPhe: 2.074 ± 0.033	5.366SerGly: 5.366 ± 0.071	1.257SerHis: 1.257 ± 0.026	2.586SerIle: 2.586 ± 0.036	1.45SerLys: 1.45 ± 0.03	5.662SerLeu: 5.662 ± 0.056	1.322SerMet: 1.322 ± 0.025	1.616SerAsn: 1.616 ± 0.032	2.863SerPro: 2.863 ± 0.038	1.824SerGln: 1.824 ± 0.031	3.857SerArg: 3.857 ± 0.046	3.161SerSer: 3.161 ± 0.059	2.994SerThr: 2.994 ± 0.051	4.144SerVal: 4.144 ± 0.048	0.723SerTrp: 0.723 ± 0.021	1.259SerTyr: 1.259 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	5.905ThrAla: 5.905 ± 0.063	0.433ThrCys: 0.433 ± 0.016	2.442ThrAsp: 2.442 ± 0.036	2.16ThrGlu: 2.16 ± 0.032	1.967ThrPhe: 1.967 ± 0.034	4.764ThrGly: 4.764 ± 0.068	1.243ThrHis: 1.243 ± 0.027	2.498ThrIle: 2.498 ± 0.043	1.201ThrLys: 1.201 ± 0.028	6.566ThrLeu: 6.566 ± 0.057	1.143ThrMet: 1.143 ± 0.021	1.34ThrAsn: 1.34 ± 0.037	3.447ThrPro: 3.447 ± 0.044	1.916ThrGln: 1.916 ± 0.032	3.675ThrArg: 3.675 ± 0.041	2.877ThrSer: 2.877 ± 0.042	2.783ThrThr: 2.783 ± 0.045	4.205ThrVal: 4.205 ± 0.051	0.71ThrTrp: 0.71 ± 0.021	1.171ThrTyr: 1.171 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	9.81ValAla: 9.81 ± 0.078	0.864ValCys: 0.864 ± 0.02	4.095ValAsp: 4.095 ± 0.064	4.337ValGlu: 4.337 ± 0.049	2.822ValPhe: 2.822 ± 0.038	5.538ValGly: 5.538 ± 0.06	1.545ValHis: 1.545 ± 0.029	3.603ValIle: 3.603 ± 0.044	2.413ValLys: 2.413 ± 0.042	7.981ValLeu: 7.981 ± 0.078	1.724ValMet: 1.724 ± 0.028	2.296ValAsn: 2.296 ± 0.044	4.056ValPro: 4.056 ± 0.053	2.438ValGln: 2.438 ± 0.035	5.461ValArg: 5.461 ± 0.055	4.642ValSer: 4.642 ± 0.055	4.383ValThr: 4.383 ± 0.054	6.336ValVal: 6.336 ± 0.07	0.985ValTrp: 0.985 ± 0.022	1.725ValTyr: 1.725 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.219TrpAla: 1.219 ± 0.025	0.158TrpCys: 0.158 ± 0.009	0.593TrpAsp: 0.593 ± 0.017	0.528TrpGlu: 0.528 ± 0.016	0.557TrpPhe: 0.557 ± 0.018	0.893TrpGly: 0.893 ± 0.023	0.411TrpHis: 0.411 ± 0.015	0.695TrpIle: 0.695 ± 0.02	0.427TrpLys: 0.427 ± 0.015	1.972TrpLeu: 1.972 ± 0.04	0.357TrpMet: 0.357 ± 0.014	0.458TrpAsn: 0.458 ± 0.014	0.683TrpPro: 0.683 ± 0.022	0.67TrpGln: 0.67 ± 0.017	1.319TrpArg: 1.319 ± 0.031	0.776TrpSer: 0.776 ± 0.023	0.722TrpThr: 0.722 ± 0.021	0.936TrpVal: 0.936 ± 0.025	0.227TrpTrp: 0.227 ± 0.011	0.33TrpTyr: 0.33 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.952TyrAla: 2.952 ± 0.04	0.28TyrCys: 0.28 ± 0.011	1.412TyrAsp: 1.412 ± 0.03	1.259TyrGlu: 1.259 ± 0.025	1.017TyrPhe: 1.017 ± 0.02	2.238TyrGly: 2.238 ± 0.039	0.504TyrHis: 0.504 ± 0.015	0.792TyrIle: 0.792 ± 0.023	0.583TyrLys: 0.583 ± 0.018	2.467TyrLeu: 2.467 ± 0.034	0.433TyrMet: 0.433 ± 0.015	0.616TyrAsn: 0.616 ± 0.02	1.215TyrPro: 1.215 ± 0.028	0.859TyrGln: 0.859 ± 0.02	1.981TyrArg: 1.981 ± 0.031	1.252TyrSer: 1.252 ± 0.025	1.251TyrThr: 1.251 ± 0.03	1.931TyrVal: 1.931 ± 0.032	0.402TyrTrp: 0.402 ± 0.014	0.64TyrTyr: 0.64 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6389 proteins (2038431 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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