Amino acid dipepetide frequency for Citrus leprosis virus C2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.994AlaAla: 3.994 ± 1.299
0.999AlaCys: 0.999 ± 0.483
2.996AlaAsp: 2.996 ± 1.213
3.245AlaGlu: 3.245 ± 1.653
0.999AlaPhe: 0.999 ± 0.936
2.996AlaGly: 2.996 ± 1.326
1.498AlaHis: 1.498 ± 0.621
3.245AlaIle: 3.245 ± 1.107
2.496AlaLys: 2.496 ± 0.982
5.741AlaLeu: 5.741 ± 0.92
1.248AlaMet: 1.248 ± 0.412
1.248AlaAsn: 1.248 ± 0.464
2.496AlaPro: 2.496 ± 1.9
1.498AlaGln: 1.498 ± 0.933
3.245AlaArg: 3.245 ± 1.233
2.746AlaSer: 2.746 ± 1.195
1.248AlaThr: 1.248 ± 0.509
6.74AlaVal: 6.74 ± 1.725
0.749AlaTrp: 0.749 ± 0.306
1.498AlaTyr: 1.498 ± 0.841
0.0AlaXaa: 0.0 ± 0.0
Cys
0.749CysAla: 0.749 ± 0.421
0.749CysCys: 0.749 ± 0.652
2.496CysAsp: 2.496 ± 0.817
1.248CysGlu: 1.248 ± 1.05
2.247CysPhe: 2.247 ± 0.846
1.747CysGly: 1.747 ± 0.748
0.499CysHis: 0.499 ± 0.304
0.749CysIle: 0.749 ± 0.502
0.749CysLys: 0.749 ± 0.306
3.245CysLeu: 3.245 ± 0.711
0.749CysMet: 0.749 ± 0.421
2.496CysAsn: 2.496 ± 0.735
1.498CysPro: 1.498 ± 0.412
0.499CysGln: 0.499 ± 0.28
1.498CysArg: 1.498 ± 1.619
2.746CysSer: 2.746 ± 1.195
1.747CysThr: 1.747 ± 0.47
2.496CysVal: 2.496 ± 0.824
0.499CysTrp: 0.499 ± 0.693
0.749CysTyr: 0.749 ± 0.652
0.0CysXaa: 0.0 ± 0.0
Asp
3.994AspAla: 3.994 ± 1.258
1.248AspCys: 1.248 ± 1.05
4.993AspAsp: 4.993 ± 1.742
2.746AspGlu: 2.746 ± 0.657
3.994AspPhe: 3.994 ± 1.395
3.744AspGly: 3.744 ± 1.013
1.498AspHis: 1.498 ± 0.412
4.743AspIle: 4.743 ± 1.166
4.244AspLys: 4.244 ± 0.924
6.74AspLeu: 6.74 ± 1.551
2.247AspMet: 2.247 ± 0.749
3.495AspAsn: 3.495 ± 1.075
2.247AspPro: 2.247 ± 0.928
2.746AspGln: 2.746 ± 0.875
2.996AspArg: 2.996 ± 0.908
6.49AspSer: 6.49 ± 1.616
1.747AspThr: 1.747 ± 0.982
3.994AspVal: 3.994 ± 0.919
0.25AspTrp: 0.25 ± 0.14
1.997AspTyr: 1.997 ± 0.559
0.0AspXaa: 0.0 ± 0.0
Glu
4.244GluAla: 4.244 ± 0.914
1.498GluCys: 1.498 ± 0.916
2.746GluAsp: 2.746 ± 1.652
3.495GluGlu: 3.495 ± 0.746
2.247GluPhe: 2.247 ± 0.736
1.248GluGly: 1.248 ± 0.676
2.996GluHis: 2.996 ± 0.516
2.247GluIle: 2.247 ± 1.216
2.996GluLys: 2.996 ± 0.586
4.493GluLeu: 4.493 ± 0.793
1.248GluMet: 1.248 ± 0.566
1.747GluAsn: 1.747 ± 0.646
1.498GluPro: 1.498 ± 0.461
0.749GluGln: 0.749 ± 0.416
2.746GluArg: 2.746 ± 0.373
3.744GluSer: 3.744 ± 1.622
1.997GluThr: 1.997 ± 0.559
3.495GluVal: 3.495 ± 0.648
0.749GluTrp: 0.749 ± 0.448
2.247GluTyr: 2.247 ± 0.939
0.0GluXaa: 0.0 ± 0.0
Phe
2.996PheAla: 2.996 ± 0.507
3.744PheCys: 3.744 ± 1.009
2.996PheAsp: 2.996 ± 0.83
4.493PheGlu: 4.493 ± 1.041
2.996PhePhe: 2.996 ± 0.849
3.495PheGly: 3.495 ± 1.601
0.749PheHis: 0.749 ± 0.421
4.743PheIle: 4.743 ± 2.047
1.997PheLys: 1.997 ± 0.792
7.489PheLeu: 7.489 ± 1.623
1.248PheMet: 1.248 ± 0.555
2.247PheAsn: 2.247 ± 0.573
3.495PhePro: 3.495 ± 0.957
0.499PheGln: 0.499 ± 0.304
3.495PheArg: 3.495 ± 0.612
5.242PheSer: 5.242 ± 0.995
3.495PheThr: 3.495 ± 0.98
3.744PheVal: 3.744 ± 1.541
0.0PheTrp: 0.0 ± 0.0
3.744PheTyr: 3.744 ± 1.4
0.0PheXaa: 0.0 ± 0.0
Gly
2.247GlyAla: 2.247 ± 0.992
1.498GlyCys: 1.498 ± 1.371
2.996GlyAsp: 2.996 ± 0.977
1.747GlyGlu: 1.747 ± 0.704
4.993GlyPhe: 4.993 ± 1.827
4.993GlyGly: 4.993 ± 1.004
0.999GlyHis: 0.999 ± 0.936
2.746GlyIle: 2.746 ± 0.733
2.496GlyLys: 2.496 ± 1.098
4.993GlyLeu: 4.993 ± 0.947
0.999GlyMet: 0.999 ± 1.18
2.746GlyAsn: 2.746 ± 0.8
1.997GlyPro: 1.997 ± 0.798
1.248GlyGln: 1.248 ± 0.578
1.248GlyArg: 1.248 ± 0.989
3.495GlySer: 3.495 ± 1.199
2.496GlyThr: 2.496 ± 1.116
4.493GlyVal: 4.493 ± 1.004
0.0GlyTrp: 0.0 ± 0.0
2.996GlyTyr: 2.996 ± 2.005
0.0GlyXaa: 0.0 ± 0.0
His
1.248HisAla: 1.248 ± 0.509
0.749HisCys: 0.749 ± 0.306
0.749HisAsp: 0.749 ± 0.65
1.248HisGlu: 1.248 ± 1.534
1.997HisPhe: 1.997 ± 0.832
0.749HisGly: 0.749 ± 0.416
0.25HisHis: 0.25 ± 0.14
3.495HisIle: 3.495 ± 0.906
0.499HisLys: 0.499 ± 0.28
1.498HisLeu: 1.498 ± 0.578
0.0HisMet: 0.0 ± 0.0
1.747HisAsn: 1.747 ± 0.982
0.999HisPro: 0.999 ± 0.773
0.999HisGln: 0.999 ± 0.572
1.498HisArg: 1.498 ± 0.592
2.996HisSer: 2.996 ± 1.184
1.248HisThr: 1.248 ± 0.894
2.746HisVal: 2.746 ± 0.751
0.0HisTrp: 0.0 ± 0.0
1.248HisTyr: 1.248 ± 0.397
0.0HisXaa: 0.0 ± 0.0
Ile
2.746IleAla: 2.746 ± 0.85
1.997IleCys: 1.997 ± 0.832
2.746IleAsp: 2.746 ± 0.54
2.746IleGlu: 2.746 ± 1.82
3.245IlePhe: 3.245 ± 1.355
2.996IleGly: 2.996 ± 0.903
1.498IleHis: 1.498 ± 0.658
4.244IleIle: 4.244 ± 1.47
3.495IleLys: 3.495 ± 1.243
5.242IleLeu: 5.242 ± 2.819
0.749IleMet: 0.749 ± 0.416
3.495IleAsn: 3.495 ± 0.814
4.244IlePro: 4.244 ± 0.54
0.749IleGln: 0.749 ± 0.782
3.245IleArg: 3.245 ± 0.998
6.49IleSer: 6.49 ± 1.752
3.245IleThr: 3.245 ± 1.133
6.241IleVal: 6.241 ± 0.932
0.25IleTrp: 0.25 ± 0.14
1.498IleTyr: 1.498 ± 0.841
0.0IleXaa: 0.0 ± 0.0
Lys
3.245LysAla: 3.245 ± 0.69
0.999LysCys: 0.999 ± 0.367
3.245LysAsp: 3.245 ± 1.343
1.248LysGlu: 1.248 ± 0.412
5.492LysPhe: 5.492 ± 1.794
1.747LysGly: 1.747 ± 0.982
1.997LysHis: 1.997 ± 0.935
2.496LysIle: 2.496 ± 1.051
2.996LysLys: 2.996 ± 1.817
6.74LysLeu: 6.74 ± 1.145
0.749LysMet: 0.749 ± 0.306
3.245LysAsn: 3.245 ± 0.935
2.746LysPro: 2.746 ± 0.991
0.999LysGln: 0.999 ± 0.561
3.495LysArg: 3.495 ± 1.153
4.743LysSer: 4.743 ± 1.094
2.996LysThr: 2.996 ± 0.648
3.744LysVal: 3.744 ± 0.979
0.749LysTrp: 0.749 ± 0.421
1.747LysTyr: 1.747 ± 0.47
0.0LysXaa: 0.0 ± 0.0
Leu
5.242LeuAla: 5.242 ± 1.668
3.994LeuCys: 3.994 ± 1.544
6.74LeuAsp: 6.74 ± 2.376
2.746LeuGlu: 2.746 ± 0.974
5.242LeuPhe: 5.242 ± 2.116
6.241LeuGly: 6.241 ± 2.794
2.247LeuHis: 2.247 ± 0.772
4.244LeuIle: 4.244 ± 0.924
6.99LeuLys: 6.99 ± 1.235
8.238LeuLeu: 8.238 ± 1.738
2.247LeuMet: 2.247 ± 0.555
4.743LeuAsn: 4.743 ± 0.3
2.496LeuPro: 2.496 ± 2.405
2.247LeuGln: 2.247 ± 0.964
5.242LeuArg: 5.242 ± 1.674
10.235LeuSer: 10.235 ± 1.423
6.49LeuThr: 6.49 ± 1.624
8.737LeuVal: 8.737 ± 1.353
0.749LeuTrp: 0.749 ± 0.439
2.247LeuTyr: 2.247 ± 0.88
0.0LeuXaa: 0.0 ± 0.0
Met
1.248MetAla: 1.248 ± 0.574
0.25MetCys: 0.25 ± 0.14
2.247MetAsp: 2.247 ± 0.821
1.498MetGlu: 1.498 ± 0.592
0.999MetPhe: 0.999 ± 0.367
0.749MetGly: 0.749 ± 0.306
1.498MetHis: 1.498 ± 0.576
0.749MetIle: 0.749 ± 0.492
0.999MetLys: 0.999 ± 1.008
2.247MetLeu: 2.247 ± 1.262
0.749MetMet: 0.749 ± 0.306
0.25MetAsn: 0.25 ± 0.558
0.25MetPro: 0.25 ± 0.14
0.749MetGln: 0.749 ± 0.421
1.498MetArg: 1.498 ± 0.578
1.498MetSer: 1.498 ± 1.016
0.25MetThr: 0.25 ± 0.14
1.498MetVal: 1.498 ± 0.963
0.0MetTrp: 0.0 ± 0.0
0.749MetTyr: 0.749 ± 0.414
0.0MetXaa: 0.0 ± 0.0
Asn
2.746AsnAla: 2.746 ± 0.818
1.997AsnCys: 1.997 ± 0.734
3.245AsnAsp: 3.245 ± 0.752
2.247AsnGlu: 2.247 ± 2.059
2.746AsnPhe: 2.746 ± 0.984
1.997AsnGly: 1.997 ± 0.808
0.499AsnHis: 0.499 ± 0.693
3.245AsnIle: 3.245 ± 0.938
3.495AsnLys: 3.495 ± 1.088
4.743AsnLeu: 4.743 ± 0.96
0.749AsnMet: 0.749 ± 0.492
2.496AsnAsn: 2.496 ± 0.895
2.247AsnPro: 2.247 ± 1.39
0.999AsnGln: 0.999 ± 0.561
3.495AsnArg: 3.495 ± 0.755
3.245AsnSer: 3.245 ± 0.938
2.247AsnThr: 2.247 ± 0.333
2.746AsnVal: 2.746 ± 0.734
0.499AsnTrp: 0.499 ± 0.28
2.496AsnTyr: 2.496 ± 1.518
0.0AsnXaa: 0.0 ± 0.0
Pro
2.247ProAla: 2.247 ± 1.79
0.25ProCys: 0.25 ± 0.36
3.245ProAsp: 3.245 ± 1.037
1.248ProGlu: 1.248 ± 0.522
1.498ProPhe: 1.498 ± 0.689
0.999ProGly: 0.999 ± 0.934
0.749ProHis: 0.749 ± 0.439
1.498ProIle: 1.498 ± 0.461
1.997ProLys: 1.997 ± 0.58
2.496ProLeu: 2.496 ± 0.653
0.25ProMet: 0.25 ± 0.14
3.744ProAsn: 3.744 ± 1.026
2.496ProPro: 2.496 ± 2.926
3.245ProGln: 3.245 ± 1.938
2.496ProArg: 2.496 ± 1.152
2.746ProSer: 2.746 ± 2.195
1.997ProThr: 1.997 ± 0.63
4.743ProVal: 4.743 ± 1.582
0.0ProTrp: 0.0 ± 0.0
0.999ProTyr: 0.999 ± 1.029
0.0ProXaa: 0.0 ± 0.0
Gln
1.498GlnAla: 1.498 ± 1.282
0.499GlnCys: 0.499 ± 0.28
1.498GlnAsp: 1.498 ± 0.841
1.248GlnGlu: 1.248 ± 0.972
1.498GlnPhe: 1.498 ± 0.689
0.749GlnGly: 0.749 ± 0.421
0.749GlnHis: 0.749 ± 0.421
2.746GlnIle: 2.746 ± 0.935
2.496GlnLys: 2.496 ± 0.884
1.997GlnLeu: 1.997 ± 0.896
0.499GlnMet: 0.499 ± 0.468
1.248GlnAsn: 1.248 ± 0.5
1.248GlnPro: 1.248 ± 0.832
1.747GlnGln: 1.747 ± 1.54
2.496GlnArg: 2.496 ± 1.488
0.25GlnSer: 0.25 ± 0.408
0.999GlnThr: 0.999 ± 0.465
1.997GlnVal: 1.997 ± 0.792
0.0GlnTrp: 0.0 ± 0.0
0.749GlnTyr: 0.749 ± 0.421
0.0GlnXaa: 0.0 ± 0.0
Arg
1.747ArgAla: 1.747 ± 0.728
2.496ArgCys: 2.496 ± 0.632
4.244ArgAsp: 4.244 ± 0.713
2.496ArgGlu: 2.496 ± 0.877
2.746ArgPhe: 2.746 ± 0.831
2.996ArgGly: 2.996 ± 1.941
1.997ArgHis: 1.997 ± 0.563
1.498ArgIle: 1.498 ± 0.491
2.746ArgLys: 2.746 ± 0.752
7.489ArgLeu: 7.489 ± 1.375
0.749ArgMet: 0.749 ± 0.405
2.247ArgAsn: 2.247 ± 1.064
0.999ArgPro: 0.999 ± 1.019
2.247ArgGln: 2.247 ± 2.247
2.996ArgArg: 2.996 ± 1.68
3.744ArgSer: 3.744 ± 0.927
3.495ArgThr: 3.495 ± 0.756
4.743ArgVal: 4.743 ± 1.74
0.499ArgTrp: 0.499 ± 0.516
2.746ArgTyr: 2.746 ± 1.011
0.0ArgXaa: 0.0 ± 0.0
Ser
2.746SerAla: 2.746 ± 1.351
2.746SerCys: 2.746 ± 1.098
4.993SerAsp: 4.993 ± 0.82
3.744SerGlu: 3.744 ± 0.828
5.492SerPhe: 5.492 ± 1.687
4.244SerGly: 4.244 ± 0.899
1.498SerHis: 1.498 ± 0.409
6.74SerIle: 6.74 ± 2.356
5.991SerLys: 5.991 ± 1.518
8.737SerLeu: 8.737 ± 1.118
0.749SerMet: 0.749 ± 0.774
3.744SerAsn: 3.744 ± 0.806
1.997SerPro: 1.997 ± 0.989
1.747SerGln: 1.747 ± 0.694
4.993SerArg: 4.993 ± 1.037
8.987SerSer: 8.987 ± 1.905
5.741SerThr: 5.741 ± 1.712
6.49SerVal: 6.49 ± 2.355
0.0SerTrp: 0.0 ± 0.0
3.994SerTyr: 3.994 ± 1.158
0.0SerXaa: 0.0 ± 0.0
Thr
1.997ThrAla: 1.997 ± 0.93
0.499ThrCys: 0.499 ± 0.516
2.746ThrAsp: 2.746 ± 0.815
2.496ThrGlu: 2.496 ± 0.927
4.493ThrPhe: 4.493 ± 1.32
2.247ThrGly: 2.247 ± 0.951
1.498ThrHis: 1.498 ± 0.848
4.743ThrIle: 4.743 ± 1.655
3.245ThrLys: 3.245 ± 1.164
5.492ThrLeu: 5.492 ± 2.132
0.749ThrMet: 0.749 ± 0.421
1.747ThrAsn: 1.747 ± 0.889
2.247ThrPro: 2.247 ± 0.857
0.749ThrGln: 0.749 ± 0.421
1.498ThrArg: 1.498 ± 0.462
3.994ThrSer: 3.994 ± 1.179
2.496ThrThr: 2.496 ± 1.054
4.743ThrVal: 4.743 ± 0.876
0.749ThrTrp: 0.749 ± 0.492
2.496ThrTyr: 2.496 ± 1.535
0.0ThrXaa: 0.0 ± 0.0
Val
4.493ValAla: 4.493 ± 1.888
2.247ValCys: 2.247 ± 0.512
5.991ValAsp: 5.991 ± 1.914
6.241ValGlu: 6.241 ± 0.777
6.99ValPhe: 6.99 ± 1.64
5.741ValGly: 5.741 ± 0.763
2.746ValHis: 2.746 ± 0.856
3.744ValIle: 3.744 ± 1.94
2.996ValLys: 2.996 ± 1.37
7.239ValLeu: 7.239 ± 1.497
1.747ValMet: 1.747 ± 0.702
2.996ValAsn: 2.996 ± 0.877
2.496ValPro: 2.496 ± 1.124
1.498ValGln: 1.498 ± 0.618
2.746ValArg: 2.746 ± 1.348
7.239ValSer: 7.239 ± 0.981
4.743ValThr: 4.743 ± 0.644
6.241ValVal: 6.241 ± 0.965
0.0ValTrp: 0.0 ± 0.0
2.996ValTyr: 2.996 ± 0.898
0.0ValXaa: 0.0 ± 0.0
Trp
0.499TrpAla: 0.499 ± 0.386
0.0TrpCys: 0.0 ± 0.0
0.499TrpAsp: 0.499 ± 0.516
0.499TrpGlu: 0.499 ± 0.28
0.999TrpPhe: 0.999 ± 0.367
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.749TrpIle: 0.749 ± 0.421
0.0TrpLys: 0.0 ± 0.0
0.499TrpLeu: 0.499 ± 0.516
0.0TrpMet: 0.0 ± 0.0
0.25TrpAsn: 0.25 ± 0.558
0.0TrpPro: 0.0 ± 0.0
0.25TrpGln: 0.25 ± 0.14
0.25TrpArg: 0.25 ± 0.533
0.0TrpSer: 0.0 ± 0.0
0.25TrpThr: 0.25 ± 0.14
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.999TrpTyr: 0.999 ± 0.607
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.999TyrAla: 0.999 ± 1.007
0.999TyrCys: 0.999 ± 0.607
4.743TyrAsp: 4.743 ± 1.639
1.747TyrGlu: 1.747 ± 0.581
1.997TyrPhe: 1.997 ± 1.07
1.747TyrGly: 1.747 ± 0.92
0.499TyrHis: 0.499 ± 0.28
2.496TyrIle: 2.496 ± 0.564
2.496TyrLys: 2.496 ± 1.017
1.997TyrLeu: 1.997 ± 0.906
1.997TyrMet: 1.997 ± 0.832
2.247TyrAsn: 2.247 ± 0.854
1.248TyrPro: 1.248 ± 0.686
0.749TyrGln: 0.749 ± 0.611
3.744TyrArg: 3.744 ± 1.133
4.993TyrSer: 4.993 ± 0.73
1.997TyrThr: 1.997 ± 1.257
1.498TyrVal: 1.498 ± 0.462
0.0TyrTrp: 0.0 ± 0.0
1.248TyrTyr: 1.248 ± 0.397
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4007 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski