Amino acid dipepetide frequency for Aliiroseovarius pelagivivens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.867AlaAla: 13.867 ± 0.199	0.993AlaCys: 0.993 ± 0.027	6.859AlaAsp: 6.859 ± 0.092	7.493AlaGlu: 7.493 ± 0.117	4.183AlaPhe: 4.183 ± 0.071	9.714AlaGly: 9.714 ± 0.134	2.277AlaHis: 2.277 ± 0.05	5.901AlaIle: 5.901 ± 0.093	4.392AlaLys: 4.392 ± 0.081	12.423AlaLeu: 12.423 ± 0.129	3.734AlaMet: 3.734 ± 0.061	2.966AlaAsn: 2.966 ± 0.059	5.195AlaPro: 5.195 ± 0.093	4.357AlaGln: 4.357 ± 0.069	7.205AlaArg: 7.205 ± 0.109	5.737AlaSer: 5.737 ± 0.077	5.755AlaThr: 5.755 ± 0.082	7.676AlaVal: 7.676 ± 0.092	1.321AlaTrp: 1.321 ± 0.038	2.525AlaTyr: 2.525 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.957CysAla: 0.957 ± 0.034	0.106CysCys: 0.106 ± 0.011	0.652CysAsp: 0.652 ± 0.026	0.485CysGlu: 0.485 ± 0.024	0.331CysPhe: 0.331 ± 0.018	0.934CysGly: 0.934 ± 0.034	0.251CysHis: 0.251 ± 0.016	0.427CysIle: 0.427 ± 0.018	0.242CysLys: 0.242 ± 0.016	0.806CysLeu: 0.806 ± 0.027	0.191CysMet: 0.191 ± 0.013	0.249CysAsn: 0.249 ± 0.017	0.552CysPro: 0.552 ± 0.023	0.255CysGln: 0.255 ± 0.015	0.464CysArg: 0.464 ± 0.023	0.488CysSer: 0.488 ± 0.023	0.457CysThr: 0.457 ± 0.023	0.638CysVal: 0.638 ± 0.028	0.107CysTrp: 0.107 ± 0.01	0.226CysTyr: 0.226 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.416AspAla: 7.416 ± 0.108	0.564AspCys: 0.564 ± 0.023	3.758AspAsp: 3.758 ± 0.061	4.085AspGlu: 4.085 ± 0.07	2.323AspPhe: 2.323 ± 0.048	5.683AspGly: 5.683 ± 0.09	1.55AspHis: 1.55 ± 0.048	3.272AspIle: 3.272 ± 0.056	2.081AspLys: 2.081 ± 0.05	6.433AspLeu: 6.433 ± 0.086	1.96AspMet: 1.96 ± 0.048	1.525AspAsn: 1.525 ± 0.04	3.53AspPro: 3.53 ± 0.066	2.229AspGln: 2.229 ± 0.055	4.017AspArg: 4.017 ± 0.068	2.271AspSer: 2.271 ± 0.048	3.145AspThr: 3.145 ± 0.061	4.621AspVal: 4.621 ± 0.068	1.132AspTrp: 1.132 ± 0.033	1.59AspTyr: 1.59 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.618GluAla: 7.618 ± 0.113	0.423GluCys: 0.423 ± 0.024	3.854GluAsp: 3.854 ± 0.071	3.66GluGlu: 3.66 ± 0.08	2.024GluPhe: 2.024 ± 0.048	4.891GluGly: 4.891 ± 0.07	1.302GluHis: 1.302 ± 0.038	3.704GluIle: 3.704 ± 0.063	2.479GluLys: 2.479 ± 0.056	5.645GluLeu: 5.645 ± 0.084	1.885GluMet: 1.885 ± 0.046	1.971GluAsn: 1.971 ± 0.05	2.384GluPro: 2.384 ± 0.051	2.053GluGln: 2.053 ± 0.048	3.953GluArg: 3.953 ± 0.068	2.209GluSer: 2.209 ± 0.052	3.635GluThr: 3.635 ± 0.063	4.336GluVal: 4.336 ± 0.067	0.703GluTrp: 0.703 ± 0.027	1.153GluTyr: 1.153 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.384PheAla: 4.384 ± 0.071	0.421PheCys: 0.421 ± 0.022	2.899PheAsp: 2.899 ± 0.058	2.33PheGlu: 2.33 ± 0.044	1.496PhePhe: 1.496 ± 0.047	3.88PheGly: 3.88 ± 0.072	0.825PheHis: 0.825 ± 0.028	1.796PheIle: 1.796 ± 0.044	1.14PheLys: 1.14 ± 0.035	3.625PheLeu: 3.625 ± 0.072	1.011PheMet: 1.011 ± 0.03	1.184PheAsn: 1.184 ± 0.034	1.635PhePro: 1.635 ± 0.044	1.153PheGln: 1.153 ± 0.032	1.942PheArg: 1.942 ± 0.042	2.203PheSer: 2.203 ± 0.055	2.256PheThr: 2.256 ± 0.048	2.772PheVal: 2.772 ± 0.059	0.587PheTrp: 0.587 ± 0.027	0.994PheTyr: 0.994 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	9.383GlyAla: 9.383 ± 0.132	0.83GlyCys: 0.83 ± 0.031	5.025GlyAsp: 5.025 ± 0.088	4.803GlyGlu: 4.803 ± 0.072	3.979GlyPhe: 3.979 ± 0.07	7.576GlyGly: 7.576 ± 0.293	1.976GlyHis: 1.976 ± 0.051	4.551GlyIle: 4.551 ± 0.076	3.656GlyLys: 3.656 ± 0.076	8.779GlyLeu: 8.779 ± 0.11	2.63GlyMet: 2.63 ± 0.052	2.355GlyAsn: 2.355 ± 0.07	3.446GlyPro: 3.446 ± 0.066	3.229GlyGln: 3.229 ± 0.061	5.118GlyArg: 5.118 ± 0.073	4.328GlySer: 4.328 ± 0.085	4.441GlyThr: 4.441 ± 0.066	6.617GlyVal: 6.617 ± 0.077	1.421GlyTrp: 1.421 ± 0.036	2.353GlyTyr: 2.353 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.327HisAla: 2.327 ± 0.057	0.23HisCys: 0.23 ± 0.015	1.391HisAsp: 1.391 ± 0.041	1.15HisGlu: 1.15 ± 0.037	0.887HisPhe: 0.887 ± 0.03	1.927HisGly: 1.927 ± 0.045	0.571HisHis: 0.571 ± 0.031	1.049HisIle: 1.049 ± 0.032	0.702HisLys: 0.702 ± 0.024	2.115HisLeu: 2.115 ± 0.051	0.673HisMet: 0.673 ± 0.025	0.548HisAsn: 0.548 ± 0.024	1.396HisPro: 1.396 ± 0.037	0.633HisGln: 0.633 ± 0.025	1.239HisArg: 1.239 ± 0.038	0.967HisSer: 0.967 ± 0.03	0.906HisThr: 0.906 ± 0.029	1.673HisVal: 1.673 ± 0.04	0.364HisTrp: 0.364 ± 0.023	0.547HisTyr: 0.547 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.888IleAla: 6.888 ± 0.096	0.634IleCys: 0.634 ± 0.026	3.529IleAsp: 3.529 ± 0.058	3.718IleGlu: 3.718 ± 0.059	1.906IlePhe: 1.906 ± 0.046	4.976IleGly: 4.976 ± 0.095	0.998IleHis: 0.998 ± 0.029	2.542IleIle: 2.542 ± 0.061	1.672IleLys: 1.672 ± 0.04	5.111IleLeu: 5.111 ± 0.076	1.283IleMet: 1.283 ± 0.04	1.512IleAsn: 1.512 ± 0.04	2.468IlePro: 2.468 ± 0.051	1.392IleGln: 1.392 ± 0.038	3.105IleArg: 3.105 ± 0.055	3.37IleSer: 3.37 ± 0.066	3.111IleThr: 3.111 ± 0.059	3.832IleVal: 3.832 ± 0.075	0.81IleTrp: 0.81 ± 0.033	1.228IleTyr: 1.228 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	4.25LysAla: 4.25 ± 0.08	0.241LysCys: 0.241 ± 0.016	2.195LysAsp: 2.195 ± 0.055	1.865LysGlu: 1.865 ± 0.044	1.154LysPhe: 1.154 ± 0.033	3.166LysGly: 3.166 ± 0.067	0.798LysHis: 0.798 ± 0.028	2.024LysIle: 2.024 ± 0.05	1.525LysLys: 1.525 ± 0.048	3.594LysLeu: 3.594 ± 0.058	1.074LysMet: 1.074 ± 0.037	1.051LysAsn: 1.051 ± 0.035	2.058LysPro: 2.058 ± 0.048	1.076LysGln: 1.076 ± 0.036	2.557LysArg: 2.557 ± 0.056	2.154LysSer: 2.154 ± 0.049	2.213LysThr: 2.213 ± 0.043	2.636LysVal: 2.636 ± 0.058	0.457LysTrp: 0.457 ± 0.022	0.738LysTyr: 0.738 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	11.371LeuAla: 11.371 ± 0.123	0.884LeuCys: 0.884 ± 0.034	6.193LeuAsp: 6.193 ± 0.09	5.53LeuGlu: 5.53 ± 0.078	3.668LeuPhe: 3.668 ± 0.073	8.422LeuGly: 8.422 ± 0.126	1.846LeuHis: 1.846 ± 0.046	5.364LeuIle: 5.364 ± 0.084	3.744LeuLys: 3.744 ± 0.06	8.481LeuLeu: 8.481 ± 0.134	2.825LeuMet: 2.825 ± 0.049	2.949LeuAsn: 2.949 ± 0.055	5.24LeuPro: 5.24 ± 0.079	2.618LeuGln: 2.618 ± 0.051	5.965LeuArg: 5.965 ± 0.086	6.983LeuSer: 6.983 ± 0.093	6.115LeuThr: 6.115 ± 0.092	6.831LeuVal: 6.831 ± 0.092	1.207LeuTrp: 1.207 ± 0.04	1.937LeuTyr: 1.937 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	3.462MetAla: 3.462 ± 0.055	0.222MetCys: 0.222 ± 0.016	1.593MetAsp: 1.593 ± 0.045	1.437MetGlu: 1.437 ± 0.043	0.924MetPhe: 0.924 ± 0.036	2.576MetGly: 2.576 ± 0.053	0.49MetHis: 0.49 ± 0.024	1.736MetIle: 1.736 ± 0.046	1.275MetLys: 1.275 ± 0.034	2.579MetLeu: 2.579 ± 0.059	0.855MetMet: 0.855 ± 0.032	0.965MetAsn: 0.965 ± 0.035	1.503MetPro: 1.503 ± 0.04	1.068MetGln: 1.068 ± 0.034	1.897MetArg: 1.897 ± 0.051	2.055MetSer: 2.055 ± 0.046	2.147MetThr: 2.147 ± 0.049	1.967MetVal: 1.967 ± 0.045	0.282MetTrp: 0.282 ± 0.017	0.373MetTyr: 0.373 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.438AsnAla: 3.438 ± 0.059	0.294AsnCys: 0.294 ± 0.019	1.657AsnAsp: 1.657 ± 0.052	1.395AsnGlu: 1.395 ± 0.037	1.049AsnPhe: 1.049 ± 0.03	2.674AsnGly: 2.674 ± 0.062	0.608AsnHis: 0.608 ± 0.025	1.58AsnIle: 1.58 ± 0.041	0.904AsnLys: 0.904 ± 0.03	2.77AsnLeu: 2.77 ± 0.053	0.782AsnMet: 0.782 ± 0.028	0.813AsnAsn: 0.813 ± 0.028	1.965AsnPro: 1.965 ± 0.044	0.846AsnGln: 0.846 ± 0.028	1.782AsnArg: 1.782 ± 0.048	1.446AsnSer: 1.446 ± 0.044	1.551AsnThr: 1.551 ± 0.045	2.13AsnVal: 2.13 ± 0.049	0.537AsnTrp: 0.537 ± 0.025	0.703AsnTyr: 0.703 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	5.06ProAla: 5.06 ± 0.089	0.334ProCys: 0.334 ± 0.018	3.891ProAsp: 3.891 ± 0.067	4.046ProGlu: 4.046 ± 0.079	2.018ProPhe: 2.018 ± 0.045	3.966ProGly: 3.966 ± 0.065	1.042ProHis: 1.042 ± 0.034	2.544ProIle: 2.544 ± 0.05	1.849ProLys: 1.849 ± 0.047	4.306ProLeu: 4.306 ± 0.068	1.355ProMet: 1.355 ± 0.034	1.592ProAsn: 1.592 ± 0.037	1.857ProPro: 1.857 ± 0.048	1.489ProGln: 1.489 ± 0.038	2.356ProArg: 2.356 ± 0.049	2.704ProSer: 2.704 ± 0.055	2.504ProThr: 2.504 ± 0.047	3.926ProVal: 3.926 ± 0.07	0.604ProTrp: 0.604 ± 0.028	1.139ProTyr: 1.139 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.895GlnAla: 3.895 ± 0.067	0.22GlnCys: 0.22 ± 0.015	1.906GlnAsp: 1.906 ± 0.053	1.615GlnGlu: 1.615 ± 0.045	1.149GlnPhe: 1.149 ± 0.041	2.536GlnGly: 2.536 ± 0.052	0.647GlnHis: 0.647 ± 0.025	2.27GlnIle: 2.27 ± 0.047	1.258GlnLys: 1.258 ± 0.036	2.896GlnLeu: 2.896 ± 0.055	1.168GlnMet: 1.168 ± 0.035	1.084GlnAsn: 1.084 ± 0.038	1.566GlnPro: 1.566 ± 0.04	1.081GlnGln: 1.081 ± 0.035	1.907GlnArg: 1.907 ± 0.049	2.006GlnSer: 2.006 ± 0.06	1.862GlnThr: 1.862 ± 0.042	2.477GlnVal: 2.477 ± 0.05	0.403GlnTrp: 0.403 ± 0.017	0.628GlnTyr: 0.628 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	6.824ArgAla: 6.824 ± 0.085	0.446ArgCys: 0.446 ± 0.021	4.021ArgAsp: 4.021 ± 0.066	3.647ArgGlu: 3.647 ± 0.08	2.531ArgPhe: 2.531 ± 0.052	4.143ArgGly: 4.143 ± 0.072	1.376ArgHis: 1.376 ± 0.037	3.445ArgIle: 3.445 ± 0.052	2.452ArgLys: 2.452 ± 0.053	6.333ArgLeu: 6.333 ± 0.093	1.891ArgMet: 1.891 ± 0.043	1.756ArgAsn: 1.756 ± 0.044	2.83ArgPro: 2.83 ± 0.059	2.072ArgGln: 2.072 ± 0.049	3.928ArgArg: 3.928 ± 0.073	3.05ArgSer: 3.05 ± 0.055	2.752ArgThr: 2.752 ± 0.045	4.476ArgVal: 4.476 ± 0.081	0.816ArgTrp: 0.816 ± 0.029	1.431ArgTyr: 1.431 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.612SerAla: 5.612 ± 0.082	0.472SerCys: 0.472 ± 0.024	3.606SerAsp: 3.606 ± 0.056	3.036SerGlu: 3.036 ± 0.057	2.534SerPhe: 2.534 ± 0.047	5.422SerGly: 5.422 ± 0.086	1.195SerHis: 1.195 ± 0.038	2.909SerIle: 2.909 ± 0.062	1.941SerLys: 1.941 ± 0.048	5.18SerLeu: 5.18 ± 0.074	1.568SerMet: 1.568 ± 0.038	1.591SerAsn: 1.591 ± 0.04	2.5SerPro: 2.5 ± 0.05	1.751SerGln: 1.751 ± 0.041	3.136SerArg: 3.136 ± 0.061	2.908SerSer: 2.908 ± 0.063	2.742SerThr: 2.742 ± 0.062	3.957SerVal: 3.957 ± 0.067	0.747SerTrp: 0.747 ± 0.029	1.366SerTyr: 1.366 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.814ThrAla: 5.814 ± 0.083	0.518ThrCys: 0.518 ± 0.028	3.305ThrAsp: 3.305 ± 0.059	3.019ThrGlu: 3.019 ± 0.059	1.981ThrPhe: 1.981 ± 0.044	5.246ThrGly: 5.246 ± 0.067	1.257ThrHis: 1.257 ± 0.041	2.861ThrIle: 2.861 ± 0.06	1.813ThrLys: 1.813 ± 0.044	5.825ThrLeu: 5.825 ± 0.072	1.379ThrMet: 1.379 ± 0.037	1.506ThrAsn: 1.506 ± 0.044	3.441ThrPro: 3.441 ± 0.065	1.798ThrGln: 1.798 ± 0.049	3.501ThrArg: 3.501 ± 0.059	2.86ThrSer: 2.86 ± 0.051	2.894ThrThr: 2.894 ± 0.055	4.037ThrVal: 4.037 ± 0.056	0.688ThrTrp: 0.688 ± 0.03	1.331ThrTyr: 1.331 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	8.231ValAla: 8.231 ± 0.107	0.606ValCys: 0.606 ± 0.025	4.333ValAsp: 4.333 ± 0.07	4.564ValGlu: 4.564 ± 0.078	2.866ValPhe: 2.866 ± 0.055	5.605ValGly: 5.605 ± 0.086	1.402ValHis: 1.402 ± 0.036	4.46ValIle: 4.46 ± 0.067	2.523ValLys: 2.523 ± 0.055	7.474ValLeu: 7.474 ± 0.109	2.134ValMet: 2.134 ± 0.038	2.181ValAsn: 2.181 ± 0.052	3.305ValPro: 3.305 ± 0.051	2.135ValGln: 2.135 ± 0.05	3.726ValArg: 3.726 ± 0.063	4.452ValSer: 4.452 ± 0.074	4.747ValThr: 4.747 ± 0.075	5.759ValVal: 5.759 ± 0.087	0.9ValTrp: 0.9 ± 0.037	1.482ValTyr: 1.482 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.381TrpAla: 1.381 ± 0.041	0.138TrpCys: 0.138 ± 0.013	0.8TrpAsp: 0.8 ± 0.028	0.695TrpGlu: 0.695 ± 0.029	0.588TrpPhe: 0.588 ± 0.025	1.041TrpGly: 1.041 ± 0.036	0.337TrpHis: 0.337 ± 0.018	0.726TrpIle: 0.726 ± 0.03	0.48TrpLys: 0.48 ± 0.024	1.512TrpLeu: 1.512 ± 0.044	0.436TrpMet: 0.436 ± 0.023	0.461TrpAsn: 0.461 ± 0.02	0.639TrpPro: 0.639 ± 0.024	0.542TrpGln: 0.542 ± 0.023	0.97TrpArg: 0.97 ± 0.034	0.784TrpSer: 0.784 ± 0.03	0.7TrpThr: 0.7 ± 0.031	0.942TrpVal: 0.942 ± 0.029	0.207TrpTrp: 0.207 ± 0.017	0.284TrpTyr: 0.284 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.391TyrAla: 2.391 ± 0.048	0.242TyrCys: 0.242 ± 0.016	1.719TyrAsp: 1.719 ± 0.046	1.307TyrGlu: 1.307 ± 0.037	0.944TyrPhe: 0.944 ± 0.028	2.117TyrGly: 2.117 ± 0.048	0.544TyrHis: 0.544 ± 0.023	0.923TyrIle: 0.923 ± 0.034	0.696TyrLys: 0.696 ± 0.028	2.286TyrLeu: 2.286 ± 0.042	0.571TyrMet: 0.571 ± 0.023	0.669TyrAsn: 0.669 ± 0.026	1.072TyrPro: 1.072 ± 0.036	0.797TyrGln: 0.797 ± 0.029	1.453TyrArg: 1.453 ± 0.04	1.2TyrSer: 1.2 ± 0.035	1.141TyrThr: 1.141 ± 0.032	1.582TyrVal: 1.582 ± 0.036	0.371TyrTrp: 0.371 ± 0.02	0.62TyrTyr: 0.62 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3215 proteins (1011528 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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