Amino acid dipepetide frequency for Sewage-associated circular DNA virus-6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.857AlaAla: 12.857 ± 1.188
0.0AlaCys: 0.0 ± 0.0
7.143AlaAsp: 7.143 ± 2.43
5.714AlaGlu: 5.714 ± 1.034
2.857AlaPhe: 2.857 ± 0.517
10.0AlaGly: 10.0 ± 6.155
0.0AlaHis: 0.0 ± 0.0
2.857AlaIle: 2.857 ± 0.517
4.286AlaLys: 4.286 ± 0.362
7.143AlaLeu: 7.143 ± 2.121
0.0AlaMet: 0.0 ± 0.0
2.857AlaAsn: 2.857 ± 1.759
5.714AlaPro: 5.714 ± 3.517
2.857AlaGln: 2.857 ± 0.517
7.143AlaArg: 7.143 ± 2.121
5.714AlaSer: 5.714 ± 3.517
1.429AlaThr: 1.429 ± 1.396
2.857AlaVal: 2.857 ± 1.759
1.429AlaTrp: 1.429 ± 1.396
2.857AlaTyr: 2.857 ± 0.517
0.0AlaXaa: 0.0 ± 0.0
Cys
2.857CysAla: 2.857 ± 2.792
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.429CysGlu: 1.429 ± 0.879
0.0CysPhe: 0.0 ± 0.0
1.429CysGly: 1.429 ± 1.396
1.429CysHis: 1.429 ± 1.396
1.429CysIle: 1.429 ± 0.879
1.429CysLys: 1.429 ± 1.396
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.429CysAsn: 1.429 ± 1.396
1.429CysPro: 1.429 ± 0.879
1.429CysGln: 1.429 ± 0.879
0.0CysArg: 0.0 ± 0.0
1.429CysSer: 1.429 ± 1.396
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.429CysTyr: 1.429 ± 1.396
0.0CysXaa: 0.0 ± 0.0
Asp
5.714AspAla: 5.714 ± 3.517
0.0AspCys: 0.0 ± 0.0
1.429AspAsp: 1.429 ± 0.879
2.857AspGlu: 2.857 ± 2.792
2.857AspPhe: 2.857 ± 0.517
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
2.857AspIle: 2.857 ± 0.517
0.0AspLys: 0.0 ± 0.0
2.857AspLeu: 2.857 ± 0.517
2.857AspMet: 2.857 ± 1.418
0.0AspAsn: 0.0 ± 0.0
1.429AspPro: 1.429 ± 1.396
4.286AspGln: 4.286 ± 0.362
1.429AspArg: 1.429 ± 1.396
0.0AspSer: 0.0 ± 0.0
5.714AspThr: 5.714 ± 1.242
5.714AspVal: 5.714 ± 1.034
5.714AspTrp: 5.714 ± 1.034
4.286AspTyr: 4.286 ± 0.362
0.0AspXaa: 0.0 ± 0.0
Glu
7.143GluAla: 7.143 ± 2.43
0.0GluCys: 0.0 ± 0.0
4.286GluAsp: 4.286 ± 2.638
1.429GluGlu: 1.429 ± 0.879
2.857GluPhe: 2.857 ± 0.517
2.857GluGly: 2.857 ± 0.517
0.0GluHis: 0.0 ± 0.0
4.286GluIle: 4.286 ± 1.913
1.429GluLys: 1.429 ± 0.879
5.714GluLeu: 5.714 ± 3.309
2.857GluMet: 2.857 ± 0.517
2.857GluAsn: 2.857 ± 0.517
1.429GluPro: 1.429 ± 1.396
0.0GluGln: 0.0 ± 0.0
2.857GluArg: 2.857 ± 0.517
5.714GluSer: 5.714 ± 5.585
1.429GluThr: 1.429 ± 0.879
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.429PheAla: 1.429 ± 0.879
1.429PheCys: 1.429 ± 1.396
0.0PheAsp: 0.0 ± 0.0
4.286PheGlu: 4.286 ± 0.362
1.429PhePhe: 1.429 ± 0.879
4.286PheGly: 4.286 ± 0.362
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.429PheLys: 1.429 ± 1.396
1.429PheLeu: 1.429 ± 0.879
1.429PheMet: 1.429 ± 1.396
2.857PheAsn: 2.857 ± 1.759
4.286PhePro: 4.286 ± 2.638
1.429PheGln: 1.429 ± 0.879
2.857PheArg: 2.857 ± 2.792
0.0PheSer: 0.0 ± 0.0
1.429PheThr: 1.429 ± 0.879
4.286PheVal: 4.286 ± 0.362
4.286PheTrp: 4.286 ± 1.913
1.429PheTyr: 1.429 ± 0.879
0.0PheXaa: 0.0 ± 0.0
Gly
11.429GlyAla: 11.429 ± 7.034
1.429GlyCys: 1.429 ± 1.396
2.857GlyAsp: 2.857 ± 0.517
1.429GlyGlu: 1.429 ± 1.396
1.429GlyPhe: 1.429 ± 0.879
8.571GlyGly: 8.571 ± 5.276
1.429GlyHis: 1.429 ± 0.879
4.286GlyIle: 4.286 ± 1.913
2.857GlyLys: 2.857 ± 2.792
2.857GlyLeu: 2.857 ± 1.759
2.857GlyMet: 2.857 ± 0.517
1.429GlyAsn: 1.429 ± 0.879
5.714GlyPro: 5.714 ± 1.242
5.714GlyGln: 5.714 ± 1.034
5.714GlyArg: 5.714 ± 3.309
5.714GlySer: 5.714 ± 1.034
4.286GlyThr: 4.286 ± 1.913
4.286GlyVal: 4.286 ± 0.362
0.0GlyTrp: 0.0 ± 0.0
5.714GlyTyr: 5.714 ± 1.034
0.0GlyXaa: 0.0 ± 0.0
His
2.857HisAla: 2.857 ± 2.792
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.429HisPhe: 1.429 ± 1.396
1.429HisGly: 1.429 ± 0.879
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.429HisLeu: 1.429 ± 1.396
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.857HisPro: 2.857 ± 1.759
0.0HisGln: 0.0 ± 0.0
1.429HisArg: 1.429 ± 0.879
1.429HisSer: 1.429 ± 1.396
2.857HisThr: 2.857 ± 1.759
0.0HisVal: 0.0 ± 0.0
1.429HisTrp: 1.429 ± 1.396
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.429IleAla: 1.429 ± 0.879
0.0IleCys: 0.0 ± 0.0
4.286IleAsp: 4.286 ± 1.913
2.857IleGlu: 2.857 ± 0.517
1.429IlePhe: 1.429 ± 1.396
1.429IleGly: 1.429 ± 0.879
1.429IleHis: 1.429 ± 1.396
2.857IleIle: 2.857 ± 0.517
5.714IleLys: 5.714 ± 1.242
0.0IleLeu: 0.0 ± 0.0
1.429IleMet: 1.429 ± 0.879
2.857IleAsn: 2.857 ± 1.759
7.143IlePro: 7.143 ± 0.154
1.429IleGln: 1.429 ± 1.396
5.714IleArg: 5.714 ± 1.034
2.857IleSer: 2.857 ± 0.517
5.714IleThr: 5.714 ± 3.309
2.857IleVal: 2.857 ± 0.517
1.429IleTrp: 1.429 ± 1.396
1.429IleTyr: 1.429 ± 0.879
0.0IleXaa: 0.0 ± 0.0
Lys
2.857LysAla: 2.857 ± 1.759
1.429LysCys: 1.429 ± 0.879
2.857LysAsp: 2.857 ± 0.517
1.429LysGlu: 1.429 ± 1.396
4.286LysPhe: 4.286 ± 0.362
4.286LysGly: 4.286 ± 0.362
1.429LysHis: 1.429 ± 0.879
4.286LysIle: 4.286 ± 0.362
11.429LysLys: 11.429 ± 0.208
5.714LysLeu: 5.714 ± 3.517
1.429LysMet: 1.429 ± 0.879
2.857LysAsn: 2.857 ± 1.759
2.857LysPro: 2.857 ± 2.792
1.429LysGln: 1.429 ± 0.879
8.571LysArg: 8.571 ± 0.725
2.857LysSer: 2.857 ± 2.792
1.429LysThr: 1.429 ± 0.879
8.571LysVal: 8.571 ± 5.276
0.0LysTrp: 0.0 ± 0.0
2.857LysTyr: 2.857 ± 1.759
0.0LysXaa: 0.0 ± 0.0
Leu
7.143LeuAla: 7.143 ± 2.121
1.429LeuCys: 1.429 ± 1.396
8.571LeuAsp: 8.571 ± 1.551
5.714LeuGlu: 5.714 ± 1.242
2.857LeuPhe: 2.857 ± 1.759
4.286LeuGly: 4.286 ± 1.913
2.857LeuHis: 2.857 ± 0.517
2.857LeuIle: 2.857 ± 0.517
7.143LeuLys: 7.143 ± 0.154
2.857LeuLeu: 2.857 ± 2.792
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
2.857LeuPro: 2.857 ± 0.517
5.714LeuGln: 5.714 ± 1.242
4.286LeuArg: 4.286 ± 4.188
5.714LeuSer: 5.714 ± 3.517
1.429LeuThr: 1.429 ± 1.396
1.429LeuVal: 1.429 ± 0.879
0.0LeuTrp: 0.0 ± 0.0
1.429LeuTyr: 1.429 ± 0.879
0.0LeuXaa: 0.0 ± 0.0
Met
1.429MetAla: 1.429 ± 0.879
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
4.286MetGlu: 4.286 ± 1.913
1.429MetPhe: 1.429 ± 0.879
1.429MetGly: 1.429 ± 1.396
0.0MetHis: 0.0 ± 0.0
1.429MetIle: 1.429 ± 0.879
4.286MetLys: 4.286 ± 2.638
1.429MetLeu: 1.429 ± 0.879
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.429MetGln: 1.429 ± 0.879
0.0MetArg: 0.0 ± 0.0
4.286MetSer: 4.286 ± 0.362
0.0MetThr: 0.0 ± 0.0
1.429MetVal: 1.429 ± 0.879
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.857AsnAla: 2.857 ± 1.759
1.429AsnCys: 1.429 ± 1.396
5.714AsnAsp: 5.714 ± 3.517
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
2.857AsnIle: 2.857 ± 1.759
4.286AsnLys: 4.286 ± 2.638
1.429AsnLeu: 1.429 ± 1.396
1.429AsnMet: 1.429 ± 0.879
2.857AsnAsn: 2.857 ± 1.759
4.286AsnPro: 4.286 ± 2.638
0.0AsnGln: 0.0 ± 0.0
2.857AsnArg: 2.857 ± 1.759
4.286AsnSer: 4.286 ± 0.362
1.429AsnThr: 1.429 ± 1.396
2.857AsnVal: 2.857 ± 0.517
2.857AsnTrp: 2.857 ± 1.759
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.714ProAla: 5.714 ± 1.242
1.429ProCys: 1.429 ± 1.396
0.0ProAsp: 0.0 ± 0.0
1.429ProGlu: 1.429 ± 1.396
1.429ProPhe: 1.429 ± 1.396
2.857ProGly: 2.857 ± 0.517
2.857ProHis: 2.857 ± 0.517
2.857ProIle: 2.857 ± 0.517
1.429ProLys: 1.429 ± 0.879
5.714ProLeu: 5.714 ± 1.242
1.429ProMet: 1.429 ± 0.879
7.143ProAsn: 7.143 ± 2.121
2.857ProPro: 2.857 ± 0.517
1.429ProGln: 1.429 ± 0.879
0.0ProArg: 0.0 ± 0.0
2.857ProSer: 2.857 ± 1.759
8.571ProThr: 8.571 ± 0.725
2.857ProVal: 2.857 ± 1.759
0.0ProTrp: 0.0 ± 0.0
5.714ProTyr: 5.714 ± 1.242
0.0ProXaa: 0.0 ± 0.0
Gln
2.857GlnAla: 2.857 ± 1.759
1.429GlnCys: 1.429 ± 0.879
0.0GlnAsp: 0.0 ± 0.0
1.429GlnGlu: 1.429 ± 1.396
2.857GlnPhe: 2.857 ± 0.517
4.286GlnGly: 4.286 ± 0.362
0.0GlnHis: 0.0 ± 0.0
1.429GlnIle: 1.429 ± 1.396
1.429GlnLys: 1.429 ± 0.879
4.286GlnLeu: 4.286 ± 0.362
1.429GlnMet: 1.429 ± 0.5
0.0GlnAsn: 0.0 ± 0.0
2.857GlnPro: 2.857 ± 1.759
1.429GlnGln: 1.429 ± 0.879
2.857GlnArg: 2.857 ± 0.517
2.857GlnSer: 2.857 ± 0.517
0.0GlnThr: 0.0 ± 0.0
1.429GlnVal: 1.429 ± 0.879
1.429GlnTrp: 1.429 ± 1.396
1.429GlnTyr: 1.429 ± 0.879
0.0GlnXaa: 0.0 ± 0.0
Arg
4.286ArgAla: 4.286 ± 1.913
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
1.429ArgGlu: 1.429 ± 0.879
2.857ArgPhe: 2.857 ± 1.759
7.143ArgGly: 7.143 ± 4.705
0.0ArgHis: 0.0 ± 0.0
2.857ArgIle: 2.857 ± 2.792
7.143ArgLys: 7.143 ± 4.396
1.429ArgLeu: 1.429 ± 1.396
2.857ArgMet: 2.857 ± 1.759
5.714ArgAsn: 5.714 ± 1.242
0.0ArgPro: 0.0 ± 0.0
1.429ArgGln: 1.429 ± 1.396
5.714ArgArg: 5.714 ± 3.309
1.429ArgSer: 1.429 ± 1.396
7.143ArgThr: 7.143 ± 4.705
5.714ArgVal: 5.714 ± 1.034
1.429ArgTrp: 1.429 ± 1.396
1.429ArgTyr: 1.429 ± 1.396
0.0ArgXaa: 0.0 ± 0.0
Ser
7.143SerAla: 7.143 ± 0.154
0.0SerCys: 0.0 ± 0.0
2.857SerAsp: 2.857 ± 0.517
2.857SerGlu: 2.857 ± 2.792
2.857SerPhe: 2.857 ± 0.517
8.571SerGly: 8.571 ± 1.551
2.857SerHis: 2.857 ± 0.517
2.857SerIle: 2.857 ± 0.517
5.714SerLys: 5.714 ± 1.034
1.429SerLeu: 1.429 ± 1.396
0.0SerMet: 0.0 ± 0.0
5.714SerAsn: 5.714 ± 1.242
1.429SerPro: 1.429 ± 0.879
2.857SerGln: 2.857 ± 1.759
2.857SerArg: 2.857 ± 2.792
1.429SerSer: 1.429 ± 1.396
8.571SerThr: 8.571 ± 5.276
1.429SerVal: 1.429 ± 1.396
0.0SerTrp: 0.0 ± 0.0
1.429SerTyr: 1.429 ± 1.396
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
4.286ThrCys: 4.286 ± 1.913
5.714ThrAsp: 5.714 ± 1.242
1.429ThrGlu: 1.429 ± 0.879
1.429ThrPhe: 1.429 ± 0.879
7.143ThrGly: 7.143 ± 2.43
2.857ThrHis: 2.857 ± 0.517
2.857ThrIle: 2.857 ± 0.517
2.857ThrLys: 2.857 ± 1.759
8.571ThrLeu: 8.571 ± 1.551
1.429ThrMet: 1.429 ± 0.879
0.0ThrAsn: 0.0 ± 0.0
1.429ThrPro: 1.429 ± 1.396
2.857ThrGln: 2.857 ± 0.517
2.857ThrArg: 2.857 ± 0.517
5.714ThrSer: 5.714 ± 1.242
0.0ThrThr: 0.0 ± 0.0
2.857ThrVal: 2.857 ± 1.759
1.429ThrTrp: 1.429 ± 1.396
5.714ThrTyr: 5.714 ± 3.517
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
2.857ValAsp: 2.857 ± 0.517
5.714ValGlu: 5.714 ± 1.034
4.286ValPhe: 4.286 ± 0.362
8.571ValGly: 8.571 ± 0.725
0.0ValHis: 0.0 ± 0.0
5.714ValIle: 5.714 ± 1.242
4.286ValLys: 4.286 ± 2.638
5.714ValLeu: 5.714 ± 3.517
0.0ValMet: 0.0 ± 0.0
1.429ValAsn: 1.429 ± 0.879
4.286ValPro: 4.286 ± 0.362
0.0ValGln: 0.0 ± 0.0
1.429ValArg: 1.429 ± 0.879
2.857ValSer: 2.857 ± 0.517
4.286ValThr: 4.286 ± 2.638
5.714ValVal: 5.714 ± 1.242
1.429ValTrp: 1.429 ± 1.396
1.429ValTyr: 1.429 ± 1.396
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.429TrpCys: 1.429 ± 1.396
1.429TrpAsp: 1.429 ± 1.396
1.429TrpGlu: 1.429 ± 1.396
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
4.286TrpIle: 4.286 ± 1.913
2.857TrpLys: 2.857 ± 0.517
4.286TrpLeu: 4.286 ± 1.913
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.429TrpGln: 1.429 ± 1.396
0.0TrpArg: 0.0 ± 0.0
4.286TrpSer: 4.286 ± 0.362
1.429TrpThr: 1.429 ± 1.396
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.429TrpTyr: 1.429 ± 1.396
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.714TyrAla: 5.714 ± 1.242
1.429TyrCys: 1.429 ± 0.879
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
1.429TyrPhe: 1.429 ± 0.879
1.429TyrGly: 1.429 ± 0.879
0.0TyrHis: 0.0 ± 0.0
1.429TyrIle: 1.429 ± 0.879
2.857TyrLys: 2.857 ± 1.759
4.286TyrLeu: 4.286 ± 1.913
0.0TyrMet: 0.0 ± 0.0
1.429TyrAsn: 1.429 ± 0.879
5.714TyrPro: 5.714 ± 1.034
0.0TyrGln: 0.0 ± 0.0
1.429TyrArg: 1.429 ± 1.396
1.429TyrSer: 1.429 ± 1.396
4.286TyrThr: 4.286 ± 2.638
5.714TyrVal: 5.714 ± 1.034
1.429TyrTrp: 1.429 ± 1.396
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (701 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski