Amino acid dipepetide frequency for Cotton leaf curl Alabad virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.267AlaAla: 6.267 ± 2.09
1.791AlaCys: 1.791 ± 1.514
0.895AlaAsp: 0.895 ± 0.757
0.0AlaGlu: 0.0 ± 0.0
0.895AlaPhe: 0.895 ± 0.631
2.686AlaGly: 2.686 ± 0.907
0.0AlaHis: 0.0 ± 0.0
1.791AlaIle: 1.791 ± 1.262
2.686AlaLys: 2.686 ± 1.359
4.476AlaLeu: 4.476 ± 1.42
0.895AlaMet: 0.895 ± 0.631
0.0AlaAsn: 0.0 ± 0.0
0.895AlaPro: 0.895 ± 0.757
4.476AlaGln: 4.476 ± 1.828
2.686AlaArg: 2.686 ± 1.319
4.476AlaSer: 4.476 ± 2.821
2.686AlaThr: 2.686 ± 2.272
1.791AlaVal: 1.791 ± 0.901
0.895AlaTrp: 0.895 ± 0.757
1.791AlaTyr: 1.791 ± 1.159
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
5.372CysCys: 5.372 ± 4.506
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.895CysPhe: 0.895 ± 0.886
1.791CysGly: 1.791 ± 0.969
1.791CysHis: 1.791 ± 0.969
1.791CysIle: 1.791 ± 1.755
0.0CysLys: 0.0 ± 0.0
0.895CysLeu: 0.895 ± 1.35
0.895CysMet: 0.895 ± 0.912
1.791CysAsn: 1.791 ± 0.969
3.581CysPro: 3.581 ± 1.885
0.895CysGln: 0.895 ± 1.35
2.686CysArg: 2.686 ± 1.721
1.791CysSer: 1.791 ± 1.819
4.476CysThr: 4.476 ± 2.896
3.581CysVal: 3.581 ± 1.522
0.0CysTrp: 0.0 ± 0.0
0.895CysTyr: 0.895 ± 1.35
0.0CysXaa: 0.0 ± 0.0
Asp
0.895AspAla: 0.895 ± 0.631
0.895AspCys: 0.895 ± 0.631
0.895AspAsp: 0.895 ± 0.91
3.581AspGlu: 3.581 ± 1.28
0.895AspPhe: 0.895 ± 0.757
0.895AspGly: 0.895 ± 0.631
0.895AspHis: 0.895 ± 0.91
3.581AspIle: 3.581 ± 1.139
2.686AspLys: 2.686 ± 0.99
3.581AspLeu: 3.581 ± 1.693
0.0AspMet: 0.0 ± 0.0
0.895AspAsn: 0.895 ± 0.757
2.686AspPro: 2.686 ± 1.839
1.791AspGln: 1.791 ± 1.318
2.686AspArg: 2.686 ± 1.381
4.476AspSer: 4.476 ± 1.362
2.686AspThr: 2.686 ± 1.93
1.791AspVal: 1.791 ± 0.942
1.791AspTrp: 1.791 ± 0.969
0.895AspTyr: 0.895 ± 0.912
0.0AspXaa: 0.0 ± 0.0
Glu
3.581GluAla: 3.581 ± 0.859
1.791GluCys: 1.791 ± 0.998
0.895GluAsp: 0.895 ± 0.631
5.372GluGlu: 5.372 ± 3.787
2.686GluPhe: 2.686 ± 1.319
2.686GluGly: 2.686 ± 1.514
0.895GluHis: 0.895 ± 0.886
0.895GluIle: 0.895 ± 0.886
3.581GluLys: 3.581 ± 2.525
2.686GluLeu: 2.686 ± 1.319
0.0GluMet: 0.0 ± 0.0
3.581GluAsn: 3.581 ± 2.093
1.791GluPro: 1.791 ± 1.091
3.581GluGln: 3.581 ± 0.859
0.895GluArg: 0.895 ± 0.757
3.581GluSer: 3.581 ± 0.859
2.686GluThr: 2.686 ± 1.604
4.476GluVal: 4.476 ± 1.42
1.791GluTrp: 1.791 ± 0.969
0.895GluTyr: 0.895 ± 0.91
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.791PheCys: 1.791 ± 0.761
2.686PheAsp: 2.686 ± 1.381
0.0PheGlu: 0.0 ± 0.0
0.895PhePhe: 0.895 ± 0.757
0.895PheGly: 0.895 ± 0.757
0.0PheHis: 0.0 ± 0.0
3.581PheIle: 3.581 ± 1.726
4.476PheLys: 4.476 ± 2.535
8.057PheLeu: 8.057 ± 2.623
0.895PheMet: 0.895 ± 0.631
3.581PheAsn: 3.581 ± 1.041
0.895PhePro: 0.895 ± 0.912
2.686PheGln: 2.686 ± 0.846
5.372PheArg: 5.372 ± 1.172
0.895PheSer: 0.895 ± 0.91
2.686PheThr: 2.686 ± 1.215
0.895PheVal: 0.895 ± 0.757
0.0PheTrp: 0.0 ± 0.0
1.791PheTyr: 1.791 ± 1.148
0.0PheXaa: 0.0 ± 0.0
Gly
1.791GlyAla: 1.791 ± 0.901
1.791GlyCys: 1.791 ± 0.998
1.791GlyAsp: 1.791 ± 0.761
1.791GlyGlu: 1.791 ± 1.091
1.791GlyPhe: 1.791 ± 1.132
2.686GlyGly: 2.686 ± 0.846
0.895GlyHis: 0.895 ± 0.631
1.791GlyIle: 1.791 ± 0.969
5.372GlyLys: 5.372 ± 2.283
2.686GlyLeu: 2.686 ± 2.144
1.791GlyMet: 1.791 ± 1.649
0.895GlyAsn: 0.895 ± 0.886
2.686GlyPro: 2.686 ± 1.893
0.895GlyGln: 0.895 ± 0.757
1.791GlyArg: 1.791 ± 2.7
5.372GlySer: 5.372 ± 2.687
1.791GlyThr: 1.791 ± 1.819
1.791GlyVal: 1.791 ± 0.901
0.0GlyTrp: 0.0 ± 0.0
1.791GlyTyr: 1.791 ± 1.132
0.0GlyXaa: 0.0 ± 0.0
His
2.686HisAla: 2.686 ± 1.381
2.686HisCys: 2.686 ± 1.024
1.791HisAsp: 1.791 ± 1.819
0.0HisGlu: 0.0 ± 0.0
2.686HisPhe: 2.686 ± 1.319
1.791HisGly: 1.791 ± 1.132
0.895HisHis: 0.895 ± 0.91
0.895HisIle: 0.895 ± 0.631
1.791HisLys: 1.791 ± 1.159
1.791HisLeu: 1.791 ± 0.969
0.0HisMet: 0.0 ± 0.0
2.686HisAsn: 2.686 ± 1.359
2.686HisPro: 2.686 ± 1.374
2.686HisGln: 2.686 ± 1.359
6.267HisArg: 6.267 ± 2.509
0.895HisSer: 0.895 ± 0.91
1.791HisThr: 1.791 ± 1.514
2.686HisVal: 2.686 ± 2.054
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.791IleCys: 1.791 ± 1.755
0.0IleAsp: 0.0 ± 0.0
0.895IleGlu: 0.895 ± 0.631
5.372IlePhe: 5.372 ± 3.058
0.895IleGly: 0.895 ± 0.757
1.791IleHis: 1.791 ± 0.969
1.791IleIle: 1.791 ± 0.901
4.476IleLys: 4.476 ± 1.738
5.372IleLeu: 5.372 ± 2.529
0.0IleMet: 0.0 ± 0.0
2.686IleAsn: 2.686 ± 1.215
2.686IlePro: 2.686 ± 1.514
4.476IleGln: 4.476 ± 1.935
6.267IleArg: 6.267 ± 1.304
6.267IleSer: 6.267 ± 2.646
1.791IleThr: 1.791 ± 0.901
2.686IleVal: 2.686 ± 1.381
2.686IleTrp: 2.686 ± 1.837
1.791IleTyr: 1.791 ± 0.998
0.0IleXaa: 0.0 ± 0.0
Lys
2.686LysAla: 2.686 ± 1.672
1.791LysCys: 1.791 ± 0.901
0.895LysAsp: 0.895 ± 0.91
4.476LysGlu: 4.476 ± 2.319
3.581LysPhe: 3.581 ± 1.119
2.686LysGly: 2.686 ± 1.359
1.791LysHis: 1.791 ± 1.262
3.581LysIle: 3.581 ± 1.783
1.791LysLys: 1.791 ± 1.34
3.581LysLeu: 3.581 ± 1.465
0.0LysMet: 0.0 ± 0.0
5.372LysAsn: 5.372 ± 2.351
4.476LysPro: 4.476 ± 1.347
2.686LysGln: 2.686 ± 1.721
2.686LysArg: 2.686 ± 1.521
1.791LysSer: 1.791 ± 0.998
3.581LysThr: 3.581 ± 0.974
2.686LysVal: 2.686 ± 1.447
0.895LysTrp: 0.895 ± 0.757
3.581LysTyr: 3.581 ± 0.974
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
2.686LeuCys: 2.686 ± 1.514
5.372LeuAsp: 5.372 ± 2.157
3.581LeuGlu: 3.581 ± 1.884
1.791LeuPhe: 1.791 ± 0.901
6.267LeuGly: 6.267 ± 1.757
5.372LeuHis: 5.372 ± 4.05
3.581LeuIle: 3.581 ± 2.269
6.267LeuLys: 6.267 ± 1.587
5.372LeuLeu: 5.372 ± 3.013
0.895LeuMet: 0.895 ± 1.269
3.581LeuAsn: 3.581 ± 1.407
2.686LeuPro: 2.686 ± 1.44
3.581LeuGln: 3.581 ± 1.271
7.162LeuArg: 7.162 ± 1.795
3.581LeuSer: 3.581 ± 1.68
5.372LeuThr: 5.372 ± 1.988
5.372LeuVal: 5.372 ± 2.058
0.895LeuTrp: 0.895 ± 1.35
4.476LeuTyr: 4.476 ± 2.454
0.0LeuXaa: 0.0 ± 0.0
Met
1.791MetAla: 1.791 ± 0.761
0.0MetCys: 0.0 ± 0.0
4.476MetAsp: 4.476 ± 1.577
0.895MetGlu: 0.895 ± 0.631
2.686MetPhe: 2.686 ± 2.272
1.791MetGly: 1.791 ± 1.288
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
4.476MetLeu: 4.476 ± 1.512
0.0MetMet: 0.0 ± 0.0
0.895MetAsn: 0.895 ± 0.757
0.895MetPro: 0.895 ± 0.631
0.895MetGln: 0.895 ± 1.35
0.895MetArg: 0.895 ± 0.91
3.581MetSer: 3.581 ± 1.403
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.791MetTrp: 1.791 ± 0.942
2.686MetTyr: 2.686 ± 1.888
0.0MetXaa: 0.0 ± 0.0
Asn
2.686AsnAla: 2.686 ± 1.175
1.791AsnCys: 1.791 ± 0.969
0.0AsnAsp: 0.0 ± 0.0
1.791AsnGlu: 1.791 ± 1.148
1.791AsnPhe: 1.791 ± 0.998
0.895AsnGly: 0.895 ± 0.886
2.686AsnHis: 2.686 ± 1.521
2.686AsnIle: 2.686 ± 1.175
0.0AsnLys: 0.0 ± 0.0
6.267AsnLeu: 6.267 ± 2.132
3.581AsnMet: 3.581 ± 1.645
1.791AsnAsn: 1.791 ± 1.091
5.372AsnPro: 5.372 ± 1.471
2.686AsnGln: 2.686 ± 1.175
3.581AsnArg: 3.581 ± 1.407
4.476AsnSer: 4.476 ± 1.877
3.581AsnThr: 3.581 ± 1.803
1.791AsnVal: 1.791 ± 0.901
0.895AsnTrp: 0.895 ± 0.631
3.581AsnTyr: 3.581 ± 0.974
0.0AsnXaa: 0.0 ± 0.0
Pro
2.686ProAla: 2.686 ± 0.99
1.791ProCys: 1.791 ± 1.132
3.581ProAsp: 3.581 ± 3.253
2.686ProGlu: 2.686 ± 1.175
1.791ProPhe: 1.791 ± 0.901
1.791ProGly: 1.791 ± 1.288
1.791ProHis: 1.791 ± 0.942
6.267ProIle: 6.267 ± 1.737
1.791ProLys: 1.791 ± 1.262
4.476ProLeu: 4.476 ± 1.668
1.791ProMet: 1.791 ± 0.761
4.476ProAsn: 4.476 ± 1.828
1.791ProPro: 1.791 ± 1.262
3.581ProGln: 3.581 ± 1.041
5.372ProArg: 5.372 ± 2.017
7.162ProSer: 7.162 ± 4.212
2.686ProThr: 2.686 ± 1.514
5.372ProVal: 5.372 ± 1.854
0.0ProTrp: 0.0 ± 0.0
1.791ProTyr: 1.791 ± 0.761
0.0ProXaa: 0.0 ± 0.0
Gln
3.581GlnAla: 3.581 ± 1.766
0.0GlnCys: 0.0 ± 0.0
4.476GlnAsp: 4.476 ± 1.466
4.476GlnGlu: 4.476 ± 1.642
2.686GlnPhe: 2.686 ± 1.374
1.791GlnGly: 1.791 ± 0.761
1.791GlnHis: 1.791 ± 1.819
2.686GlnIle: 2.686 ± 1.44
0.895GlnLys: 0.895 ± 0.631
4.476GlnLeu: 4.476 ± 2.193
0.895GlnMet: 0.895 ± 0.631
0.895GlnAsn: 0.895 ± 0.91
2.686GlnPro: 2.686 ± 1.839
2.686GlnGln: 2.686 ± 1.655
0.895GlnArg: 0.895 ± 0.631
3.581GlnSer: 3.581 ± 1.884
2.686GlnThr: 2.686 ± 1.672
4.476GlnVal: 4.476 ± 1.198
0.0GlnTrp: 0.0 ± 0.0
2.686GlnTyr: 2.686 ± 0.907
0.0GlnXaa: 0.0 ± 0.0
Arg
1.791ArgAla: 1.791 ± 1.514
3.581ArgCys: 3.581 ± 3.028
3.581ArgAsp: 3.581 ± 1.49
4.476ArgGlu: 4.476 ± 2.05
0.895ArgPhe: 0.895 ± 0.757
1.791ArgGly: 1.791 ± 1.132
3.581ArgHis: 3.581 ± 1.885
6.267ArgIle: 6.267 ± 2.29
2.686ArgLys: 2.686 ± 1.655
2.686ArgLeu: 2.686 ± 1.708
3.581ArgMet: 3.581 ± 2.295
2.686ArgAsn: 2.686 ± 1.319
6.267ArgPro: 6.267 ± 2.117
2.686ArgGln: 2.686 ± 1.024
8.057ArgArg: 8.057 ± 3.253
8.953ArgSer: 8.953 ± 3.408
3.581ArgThr: 3.581 ± 1.803
8.057ArgVal: 8.057 ± 2.723
0.895ArgTrp: 0.895 ± 1.35
3.581ArgTyr: 3.581 ± 2.393
0.0ArgXaa: 0.0 ± 0.0
Ser
0.895SerAla: 0.895 ± 0.631
0.895SerCys: 0.895 ± 0.912
1.791SerAsp: 1.791 ± 0.969
5.372SerGlu: 5.372 ± 2.076
4.476SerPhe: 4.476 ± 1.594
1.791SerGly: 1.791 ± 1.589
2.686SerHis: 2.686 ± 1.318
5.372SerIle: 5.372 ± 2.256
6.267SerLys: 6.267 ± 2.455
2.686SerLeu: 2.686 ± 1.514
2.686SerMet: 2.686 ± 1.458
4.476SerAsn: 4.476 ± 1.594
6.267SerPro: 6.267 ± 2.172
1.791SerGln: 1.791 ± 1.824
8.953SerArg: 8.953 ± 2.28
11.638SerSer: 11.638 ± 6.244
6.267SerThr: 6.267 ± 2.404
5.372SerVal: 5.372 ± 3.082
0.0SerTrp: 0.0 ± 0.0
3.581SerTyr: 3.581 ± 2.618
0.0SerXaa: 0.0 ± 0.0
Thr
3.581ThrAla: 3.581 ± 1.041
0.0ThrCys: 0.0 ± 0.0
0.895ThrAsp: 0.895 ± 1.35
1.791ThrGlu: 1.791 ± 1.514
0.895ThrPhe: 0.895 ± 0.886
6.267ThrGly: 6.267 ± 1.646
7.162ThrHis: 7.162 ± 3.166
1.791ThrIle: 1.791 ± 0.901
2.686ThrLys: 2.686 ± 1.381
5.372ThrLeu: 5.372 ± 1.172
4.476ThrMet: 4.476 ± 1.08
4.476ThrAsn: 4.476 ± 2.07
6.267ThrPro: 6.267 ± 2.313
0.895ThrGln: 0.895 ± 0.886
1.791ThrArg: 1.791 ± 1.159
2.686ThrSer: 2.686 ± 1.893
3.581ThrThr: 3.581 ± 1.654
3.581ThrVal: 3.581 ± 1.49
0.0ThrTrp: 0.0 ± 0.0
0.895ThrTyr: 0.895 ± 0.631
0.0ThrXaa: 0.0 ± 0.0
Val
0.895ValAla: 0.895 ± 0.631
0.895ValCys: 0.895 ± 0.757
2.686ValAsp: 2.686 ± 1.318
3.581ValGlu: 3.581 ± 1.947
3.581ValPhe: 3.581 ± 1.698
0.0ValGly: 0.0 ± 0.0
0.895ValHis: 0.895 ± 0.912
4.476ValIle: 4.476 ± 2.454
5.372ValLys: 5.372 ± 2.119
4.476ValLeu: 4.476 ± 2.239
1.791ValMet: 1.791 ± 0.761
4.476ValAsn: 4.476 ± 1.018
7.162ValPro: 7.162 ± 1.398
3.581ValGln: 3.581 ± 2.036
6.267ValArg: 6.267 ± 5.301
3.581ValSer: 3.581 ± 1.929
4.476ValThr: 4.476 ± 2.097
0.895ValVal: 0.895 ± 0.757
0.0ValTrp: 0.0 ± 0.0
4.476ValTyr: 4.476 ± 2.097
0.0ValXaa: 0.0 ± 0.0
Trp
1.791TrpAla: 1.791 ± 1.262
0.0TrpCys: 0.0 ± 0.0
0.895TrpAsp: 0.895 ± 0.912
0.895TrpGlu: 0.895 ± 0.886
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.895TrpHis: 0.895 ± 0.757
0.0TrpIle: 0.0 ± 0.0
0.895TrpLys: 0.895 ± 1.35
0.895TrpLeu: 0.895 ± 1.35
0.895TrpMet: 0.895 ± 0.757
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.895TrpGln: 0.895 ± 0.631
0.895TrpArg: 0.895 ± 0.91
0.895TrpSer: 0.895 ± 0.91
1.791TrpThr: 1.791 ± 1.091
0.895TrpVal: 0.895 ± 0.631
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.476TyrAla: 4.476 ± 2.146
1.791TyrCys: 1.791 ± 1.34
0.895TyrAsp: 0.895 ± 0.757
2.686TyrGlu: 2.686 ± 1.93
1.791TyrPhe: 1.791 ± 1.091
1.791TyrGly: 1.791 ± 0.969
0.895TyrHis: 0.895 ± 0.631
0.895TyrIle: 0.895 ± 0.886
0.895TyrLys: 0.895 ± 0.631
4.476TyrLeu: 4.476 ± 1.803
1.791TyrMet: 1.791 ± 1.041
2.686TyrAsn: 2.686 ± 1.837
0.895TyrPro: 0.895 ± 0.631
0.895TyrGln: 0.895 ± 0.757
4.476TyrArg: 4.476 ± 3.065
3.581TyrSer: 3.581 ± 0.974
0.895TyrThr: 0.895 ± 0.91
5.372TyrVal: 5.372 ± 1.523
0.0TyrTrp: 0.0 ± 0.0
1.791TyrTyr: 1.791 ± 0.969
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1118 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski