Amino acid dipepetide frequency for Lampropedia puyangensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.372AlaAla: 14.372 ± 0.151	1.267AlaCys: 1.267 ± 0.036	5.396AlaAsp: 5.396 ± 0.075	5.414AlaGlu: 5.414 ± 0.08	3.986AlaPhe: 3.986 ± 0.069	8.632AlaGly: 8.632 ± 0.096	3.006AlaHis: 3.006 ± 0.067	6.157AlaIle: 6.157 ± 0.074	4.355AlaLys: 4.355 ± 0.076	14.255AlaLeu: 14.255 ± 0.145	3.308AlaMet: 3.308 ± 0.052	3.581AlaAsn: 3.581 ± 0.054	5.422AlaPro: 5.422 ± 0.086	7.776AlaGln: 7.776 ± 0.107	6.535AlaArg: 6.535 ± 0.079	7.09AlaSer: 7.09 ± 0.085	6.129AlaThr: 6.129 ± 0.078	8.092AlaVal: 8.092 ± 0.097	1.88AlaTrp: 1.88 ± 0.046	2.61AlaTyr: 2.61 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.081CysAla: 1.081 ± 0.032	0.116CysCys: 0.116 ± 0.01	0.507CysAsp: 0.507 ± 0.021	0.454CysGlu: 0.454 ± 0.021	0.333CysPhe: 0.333 ± 0.019	0.838CysGly: 0.838 ± 0.032	0.247CysHis: 0.247 ± 0.015	0.48CysIle: 0.48 ± 0.021	0.279CysLys: 0.279 ± 0.015	0.869CysLeu: 0.869 ± 0.027	0.276CysMet: 0.276 ± 0.015	0.28CysAsn: 0.28 ± 0.017	0.458CysPro: 0.458 ± 0.021	0.359CysGln: 0.359 ± 0.018	0.427CysArg: 0.427 ± 0.019	0.598CysSer: 0.598 ± 0.028	0.57CysThr: 0.57 ± 0.023	0.64CysVal: 0.64 ± 0.023	0.118CysTrp: 0.118 ± 0.01	0.184CysTyr: 0.184 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.36AspAla: 6.36 ± 0.091	0.426AspCys: 0.426 ± 0.019	2.387AspAsp: 2.387 ± 0.051	2.682AspGlu: 2.682 ± 0.049	1.992AspPhe: 1.992 ± 0.046	3.977AspGly: 3.977 ± 0.062	1.017AspHis: 1.017 ± 0.032	2.543AspIle: 2.543 ± 0.045	1.695AspLys: 1.695 ± 0.043	4.888AspLeu: 4.888 ± 0.069	1.223AspMet: 1.223 ± 0.03	1.374AspAsn: 1.374 ± 0.037	2.314AspPro: 2.314 ± 0.049	1.849AspGln: 1.849 ± 0.035	2.58AspArg: 2.58 ± 0.052	2.537AspSer: 2.537 ± 0.047	2.585AspThr: 2.585 ± 0.052	3.993AspVal: 3.993 ± 0.063	0.991AspTrp: 0.991 ± 0.026	1.397AspTyr: 1.397 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	5.838GluAla: 5.838 ± 0.086	0.394GluCys: 0.394 ± 0.021	2.236GluAsp: 2.236 ± 0.044	2.607GluGlu: 2.607 ± 0.06	1.665GluPhe: 1.665 ± 0.041	3.518GluGly: 3.518 ± 0.068	1.456GluHis: 1.456 ± 0.039	2.63GluIle: 2.63 ± 0.051	2.194GluLys: 2.194 ± 0.05	5.244GluLeu: 5.244 ± 0.069	1.264GluMet: 1.264 ± 0.033	1.486GluAsn: 1.486 ± 0.037	2.321GluPro: 2.321 ± 0.045	3.298GluGln: 3.298 ± 0.062	3.863GluArg: 3.863 ± 0.075	2.66GluSer: 2.66 ± 0.046	2.537GluThr: 2.537 ± 0.05	3.872GluVal: 3.872 ± 0.065	0.744GluTrp: 0.744 ± 0.03	1.088GluTyr: 1.088 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.095PheAla: 4.095 ± 0.073	0.377PheCys: 0.377 ± 0.019	2.332PheAsp: 2.332 ± 0.046	2.006PheGlu: 2.006 ± 0.043	1.429PhePhe: 1.429 ± 0.041	3.161PheGly: 3.161 ± 0.06	0.731PheHis: 0.731 ± 0.027	1.686PheIle: 1.686 ± 0.043	1.26PheLys: 1.26 ± 0.033	3.098PheLeu: 3.098 ± 0.066	0.864PheMet: 0.864 ± 0.031	1.274PheAsn: 1.274 ± 0.036	1.469PhePro: 1.469 ± 0.037	1.196PheGln: 1.196 ± 0.029	1.532PheArg: 1.532 ± 0.039	2.474PheSer: 2.474 ± 0.051	2.001PheThr: 2.001 ± 0.043	2.606PheVal: 2.606 ± 0.053	0.558PheTrp: 0.558 ± 0.023	0.88PheTyr: 0.88 ± 0.03	0.001PheXaa: 0.001 ± 0.001
Gly	7.954GlyAla: 7.954 ± 0.097	0.797GlyCys: 0.797 ± 0.031	3.4GlyAsp: 3.4 ± 0.06	3.668GlyGlu: 3.668 ± 0.053	3.135GlyPhe: 3.135 ± 0.054	5.764GlyGly: 5.764 ± 0.095	1.933GlyHis: 1.933 ± 0.045	4.239GlyIle: 4.239 ± 0.063	3.283GlyLys: 3.283 ± 0.056	8.3GlyLeu: 8.3 ± 0.1	2.253GlyMet: 2.253 ± 0.043	2.377GlyAsn: 2.377 ± 0.053	2.563GlyPro: 2.563 ± 0.051	4.122GlyGln: 4.122 ± 0.071	4.124GlyArg: 4.124 ± 0.066	4.625GlySer: 4.625 ± 0.068	3.98GlyThr: 3.98 ± 0.068	6.086GlyVal: 6.086 ± 0.085	1.287GlyTrp: 1.287 ± 0.039	2.303GlyTyr: 2.303 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	3.202HisAla: 3.202 ± 0.062	0.309HisCys: 0.309 ± 0.017	1.237HisAsp: 1.237 ± 0.042	1.201HisGlu: 1.201 ± 0.033	1.02HisPhe: 1.02 ± 0.029	1.955HisGly: 1.955 ± 0.046	0.728HisHis: 0.728 ± 0.026	1.395HisIle: 1.395 ± 0.034	0.658HisLys: 0.658 ± 0.026	2.446HisLeu: 2.446 ± 0.052	0.65HisMet: 0.65 ± 0.024	0.732HisAsn: 0.732 ± 0.027	1.481HisPro: 1.481 ± 0.044	1.164HisGln: 1.164 ± 0.033	1.303HisArg: 1.303 ± 0.035	1.401HisSer: 1.401 ± 0.033	1.416HisThr: 1.416 ± 0.041	1.722HisVal: 1.722 ± 0.04	0.545HisTrp: 0.545 ± 0.025	0.73HisTyr: 0.73 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.776IleAla: 6.776 ± 0.083	0.432IleCys: 0.432 ± 0.02	2.99IleAsp: 2.99 ± 0.051	3.327IleGlu: 3.327 ± 0.056	1.507IlePhe: 1.507 ± 0.043	4.357IleGly: 4.357 ± 0.074	1.164IleHis: 1.164 ± 0.034	1.874IleIle: 1.874 ± 0.051	1.728IleLys: 1.728 ± 0.039	3.876IleLeu: 3.876 ± 0.067	0.946IleMet: 0.946 ± 0.028	1.757IleAsn: 1.757 ± 0.047	2.36IlePro: 2.36 ± 0.047	1.833IleGln: 1.833 ± 0.036	2.686IleArg: 2.686 ± 0.056	3.007IleSer: 3.007 ± 0.053	2.931IleThr: 2.931 ± 0.054	3.759IleVal: 3.759 ± 0.053	0.593IleTrp: 0.593 ± 0.026	1.116IleTyr: 1.116 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.277LysAla: 4.277 ± 0.076	0.16LysCys: 0.16 ± 0.014	1.762LysAsp: 1.762 ± 0.042	1.838LysGlu: 1.838 ± 0.048	0.812LysPhe: 0.812 ± 0.026	2.591LysGly: 2.591 ± 0.05	0.842LysHis: 0.842 ± 0.025	1.628LysIle: 1.628 ± 0.043	1.591LysLys: 1.591 ± 0.049	3.399LysLeu: 3.399 ± 0.053	0.795LysMet: 0.795 ± 0.027	1.312LysAsn: 1.312 ± 0.033	2.164LysPro: 2.164 ± 0.043	1.687LysGln: 1.687 ± 0.043	2.326LysArg: 2.326 ± 0.05	1.906LysSer: 1.906 ± 0.041	2.296LysThr: 2.296 ± 0.05	2.574LysVal: 2.574 ± 0.058	0.375LysTrp: 0.375 ± 0.019	0.71LysTyr: 0.71 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	12.995LeuAla: 12.995 ± 0.133	1.107LeuCys: 1.107 ± 0.033	5.416LeuAsp: 5.416 ± 0.073	5.354LeuGlu: 5.354 ± 0.075	3.401LeuPhe: 3.401 ± 0.057	8.089LeuGly: 8.089 ± 0.108	2.786LeuHis: 2.786 ± 0.062	4.775LeuIle: 4.775 ± 0.079	3.57LeuLys: 3.57 ± 0.056	11.363LeuLeu: 11.363 ± 0.145	2.53LeuMet: 2.53 ± 0.051	3.338LeuAsn: 3.338 ± 0.053	5.89LeuPro: 5.89 ± 0.078	5.897LeuGln: 5.897 ± 0.09	6.671LeuArg: 6.671 ± 0.083	6.587LeuSer: 6.587 ± 0.085	5.498LeuThr: 5.498 ± 0.069	7.466LeuVal: 7.466 ± 0.099	1.395LeuTrp: 1.395 ± 0.041	2.17LeuTyr: 2.17 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	3.122MetAla: 3.122 ± 0.056	0.167MetCys: 0.167 ± 0.012	1.087MetAsp: 1.087 ± 0.029	1.086MetGlu: 1.086 ± 0.033	0.705MetPhe: 0.705 ± 0.028	1.984MetGly: 1.984 ± 0.042	0.664MetHis: 0.664 ± 0.026	0.94MetIle: 0.94 ± 0.032	0.837MetLys: 0.837 ± 0.029	2.701MetLeu: 2.701 ± 0.053	0.564MetMet: 0.564 ± 0.025	0.834MetAsn: 0.834 ± 0.026	1.531MetPro: 1.531 ± 0.032	1.513MetGln: 1.513 ± 0.033	1.658MetArg: 1.658 ± 0.04	1.483MetSer: 1.483 ± 0.035	1.55MetThr: 1.55 ± 0.038	1.907MetVal: 1.907 ± 0.04	0.208MetTrp: 0.208 ± 0.014	0.409MetTyr: 0.409 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	4.015AsnAla: 4.015 ± 0.075	0.267AsnCys: 0.267 ± 0.015	1.473AsnAsp: 1.473 ± 0.034	1.422AsnGlu: 1.422 ± 0.031	0.977AsnPhe: 0.977 ± 0.029	2.581AsnGly: 2.581 ± 0.049	0.762AsnHis: 0.762 ± 0.024	1.557AsnIle: 1.557 ± 0.04	1.061AsnLys: 1.061 ± 0.032	2.992AsnLeu: 2.992 ± 0.05	0.724AsnMet: 0.724 ± 0.027	1.118AsnAsn: 1.118 ± 0.039	2.011AsnPro: 2.011 ± 0.043	1.362AsnGln: 1.362 ± 0.034	1.789AsnArg: 1.789 ± 0.039	1.679AsnSer: 1.679 ± 0.043	2.153AsnThr: 2.153 ± 0.053	2.197AsnVal: 2.197 ± 0.05	0.493AsnTrp: 0.493 ± 0.021	0.813AsnTyr: 0.813 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	5.932ProAla: 5.932 ± 0.09	0.347ProCys: 0.347 ± 0.017	2.593ProAsp: 2.593 ± 0.053	3.071ProGlu: 3.071 ± 0.057	1.849ProPhe: 1.849 ± 0.04	3.412ProGly: 3.412 ± 0.057	1.32ProHis: 1.32 ± 0.03	2.294ProIle: 2.294 ± 0.045	1.58ProLys: 1.58 ± 0.036	5.16ProLeu: 5.16 ± 0.066	1.246ProMet: 1.246 ± 0.035	1.541ProAsn: 1.541 ± 0.034	2.04ProPro: 2.04 ± 0.054	2.614ProGln: 2.614 ± 0.052	2.215ProArg: 2.215 ± 0.044	3.216ProSer: 3.216 ± 0.056	2.805ProThr: 2.805 ± 0.052	4.023ProVal: 4.023 ± 0.065	0.778ProTrp: 0.778 ± 0.027	1.235ProTyr: 1.235 ± 0.038	0.001ProXaa: 0.001 ± 0.001
Gln	7.363GlnAla: 7.363 ± 0.099	0.444GlnCys: 0.444 ± 0.021	2.081GlnAsp: 2.081 ± 0.045	2.741GlnGlu: 2.741 ± 0.056	1.507GlnPhe: 1.507 ± 0.035	3.771GlnGly: 3.771 ± 0.066	1.491GlnHis: 1.491 ± 0.043	2.126GlnIle: 2.126 ± 0.044	1.573GlnLys: 1.573 ± 0.038	5.457GlnLeu: 5.457 ± 0.094	1.151GlnMet: 1.151 ± 0.028	1.266GlnAsn: 1.266 ± 0.033	2.541GlnPro: 2.541 ± 0.052	3.22GlnGln: 3.22 ± 0.073	3.69GlnArg: 3.69 ± 0.065	3.125GlnSer: 3.125 ± 0.056	2.995GlnThr: 2.995 ± 0.059	3.657GlnVal: 3.657 ± 0.061	1.308GlnTrp: 1.308 ± 0.034	1.14GlnTyr: 1.14 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	5.783ArgAla: 5.783 ± 0.082	0.452ArgCys: 0.452 ± 0.022	2.827ArgAsp: 2.827 ± 0.054	3.173ArgGlu: 3.173 ± 0.061	2.354ArgPhe: 2.354 ± 0.045	3.499ArgGly: 3.499 ± 0.067	1.594ArgHis: 1.594 ± 0.036	3.487ArgIle: 3.487 ± 0.056	2.177ArgLys: 2.177 ± 0.047	6.599ArgLeu: 6.599 ± 0.079	1.67ArgMet: 1.67 ± 0.04	2.006ArgAsn: 2.006 ± 0.044	2.393ArgPro: 2.393 ± 0.042	3.184ArgGln: 3.184 ± 0.069	3.274ArgArg: 3.274 ± 0.061	3.334ArgSer: 3.334 ± 0.064	2.992ArgThr: 2.992 ± 0.048	4.053ArgVal: 4.053 ± 0.064	1.051ArgTrp: 1.051 ± 0.029	1.785ArgTyr: 1.785 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.813SerAla: 6.813 ± 0.091	0.443SerCys: 0.443 ± 0.02	2.759SerAsp: 2.759 ± 0.056	2.701SerGlu: 2.701 ± 0.052	2.201SerPhe: 2.201 ± 0.049	5.167SerGly: 5.167 ± 0.07	1.518SerHis: 1.518 ± 0.039	3.25SerIle: 3.25 ± 0.052	2.056SerLys: 2.056 ± 0.049	6.145SerLeu: 6.145 ± 0.086	1.455SerMet: 1.455 ± 0.034	2.015SerAsn: 2.015 ± 0.047	2.949SerPro: 2.949 ± 0.059	2.71SerGln: 2.71 ± 0.054	3.18SerArg: 3.18 ± 0.054	4.022SerSer: 4.022 ± 0.07	3.632SerThr: 3.632 ± 0.064	4.24SerVal: 4.24 ± 0.062	0.8SerTrp: 0.8 ± 0.028	1.472SerTyr: 1.472 ± 0.042	0.001SerXaa: 0.001 ± 0.001
Thr	6.357ThrAla: 6.357 ± 0.089	0.415ThrCys: 0.415 ± 0.02	2.534ThrAsp: 2.534 ± 0.051	2.514ThrGlu: 2.514 ± 0.046	1.807ThrPhe: 1.807 ± 0.049	4.539ThrGly: 4.539 ± 0.064	1.395ThrHis: 1.395 ± 0.029	2.798ThrIle: 2.798 ± 0.056	1.567ThrLys: 1.567 ± 0.041	6.28ThrLeu: 6.28 ± 0.083	1.202ThrMet: 1.202 ± 0.034	1.708ThrAsn: 1.708 ± 0.047	3.771ThrPro: 3.771 ± 0.066	2.739ThrGln: 2.739 ± 0.048	2.776ThrArg: 2.776 ± 0.058	3.356ThrSer: 3.356 ± 0.06	3.38ThrThr: 3.38 ± 0.068	4.257ThrVal: 4.257 ± 0.071	0.812ThrTrp: 0.812 ± 0.029	1.286ThrTyr: 1.286 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	8.747ValAla: 8.747 ± 0.093	0.765ValCys: 0.765 ± 0.028	3.885ValAsp: 3.885 ± 0.057	3.78ValGlu: 3.78 ± 0.074	2.758ValPhe: 2.758 ± 0.056	5.185ValGly: 5.185 ± 0.079	1.739ValHis: 1.739 ± 0.044	3.507ValIle: 3.507 ± 0.059	2.338ValLys: 2.338 ± 0.057	8.467ValLeu: 8.467 ± 0.098	1.9ValMet: 1.9 ± 0.043	2.216ValAsn: 2.216 ± 0.052	3.665ValPro: 3.665 ± 0.06	3.884ValGln: 3.884 ± 0.059	4.352ValArg: 4.352 ± 0.061	4.076ValSer: 4.076 ± 0.059	3.952ValThr: 3.952 ± 0.079	6.421ValVal: 6.421 ± 0.096	1.058ValTrp: 1.058 ± 0.031	1.622ValTyr: 1.622 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.391TrpAla: 1.391 ± 0.038	0.167TrpCys: 0.167 ± 0.012	0.681TrpAsp: 0.681 ± 0.026	0.579TrpGlu: 0.579 ± 0.023	0.593TrpPhe: 0.593 ± 0.026	1.057TrpGly: 1.057 ± 0.033	0.423TrpHis: 0.423 ± 0.018	0.709TrpIle: 0.709 ± 0.024	0.501TrpLys: 0.501 ± 0.022	2.316TrpLeu: 2.316 ± 0.053	0.451TrpMet: 0.451 ± 0.021	0.534TrpAsn: 0.534 ± 0.021	0.776TrpPro: 0.776 ± 0.033	1.091TrpGln: 1.091 ± 0.033	1.173TrpArg: 1.173 ± 0.04	0.933TrpSer: 0.933 ± 0.031	0.664TrpThr: 0.664 ± 0.026	1.08TrpVal: 1.08 ± 0.033	0.294TrpTrp: 0.294 ± 0.02	0.337TrpTyr: 0.337 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.788TyrAla: 2.788 ± 0.05	0.259TyrCys: 0.259 ± 0.015	1.228TyrAsp: 1.228 ± 0.044	1.296TyrGlu: 1.296 ± 0.033	0.997TyrPhe: 0.997 ± 0.028	2.117TyrGly: 2.117 ± 0.047	0.479TyrHis: 0.479 ± 0.019	0.942TyrIle: 0.942 ± 0.034	0.742TyrLys: 0.742 ± 0.027	2.446TyrLeu: 2.446 ± 0.046	0.477TyrMet: 0.477 ± 0.022	0.699TyrAsn: 0.699 ± 0.029	1.154TyrPro: 1.154 ± 0.033	1.148TyrGln: 1.148 ± 0.034	1.532TyrArg: 1.532 ± 0.035	1.421TyrSer: 1.421 ± 0.036	1.427TyrThr: 1.427 ± 0.038	1.673TyrVal: 1.673 ± 0.035	0.46TyrTrp: 0.46 ± 0.018	0.636TyrTyr: 0.636 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.001XaaGln: 0.001 ± 0.001	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3366 proteins (1140859 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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