Amino acid dipepetide frequency for Erwinia mallotivora

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.566AlaAla: 10.566 ± 0.133	1.109AlaCys: 1.109 ± 0.029	5.205AlaAsp: 5.205 ± 0.067	5.998AlaGlu: 5.998 ± 0.081	3.534AlaPhe: 3.534 ± 0.055	8.184AlaGly: 8.184 ± 0.094	1.74AlaHis: 1.74 ± 0.036	5.356AlaIle: 5.356 ± 0.071	3.416AlaLys: 3.416 ± 0.071	11.809AlaLeu: 11.809 ± 0.125	2.86AlaMet: 2.86 ± 0.057	2.662AlaAsn: 2.662 ± 0.051	3.408AlaPro: 3.408 ± 0.055	4.272AlaGln: 4.272 ± 0.08	5.757AlaArg: 5.757 ± 0.081	6.022AlaSer: 6.022 ± 0.083	4.967AlaThr: 4.967 ± 0.07	7.006AlaVal: 7.006 ± 0.089	1.608AlaTrp: 1.608 ± 0.037	1.828AlaTyr: 1.828 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.939CysAla: 0.939 ± 0.028	0.216CysCys: 0.216 ± 0.014	0.58CysAsp: 0.58 ± 0.022	0.586CysGlu: 0.586 ± 0.024	0.48CysPhe: 0.48 ± 0.022	1.047CysGly: 1.047 ± 0.034	0.361CysHis: 0.361 ± 0.02	0.551CysIle: 0.551 ± 0.022	0.328CysLys: 0.328 ± 0.016	1.101CysLeu: 1.101 ± 0.033	0.224CysMet: 0.224 ± 0.013	0.314CysAsn: 0.314 ± 0.014	0.509CysPro: 0.509 ± 0.022	0.535CysGln: 0.535 ± 0.021	0.651CysArg: 0.651 ± 0.026	0.705CysSer: 0.705 ± 0.023	0.517CysThr: 0.517 ± 0.021	0.692CysVal: 0.692 ± 0.024	0.213CysTrp: 0.213 ± 0.014	0.347CysTyr: 0.347 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.166AspAla: 5.166 ± 0.072	0.55AspCys: 0.55 ± 0.025	2.842AspAsp: 2.842 ± 0.055	3.335AspGlu: 3.335 ± 0.055	2.233AspPhe: 2.233 ± 0.042	3.786AspGly: 3.786 ± 0.053	1.019AspHis: 1.019 ± 0.031	3.366AspIle: 3.366 ± 0.062	2.359AspLys: 2.359 ± 0.049	4.635AspLeu: 4.635 ± 0.062	1.305AspMet: 1.305 ± 0.032	2.267AspAsn: 2.267 ± 0.043	2.116AspPro: 2.116 ± 0.043	1.746AspGln: 1.746 ± 0.041	2.874AspArg: 2.874 ± 0.053	3.164AspSer: 3.164 ± 0.052	2.485AspThr: 2.485 ± 0.04	3.508AspVal: 3.508 ± 0.054	0.846AspTrp: 0.846 ± 0.027	1.917AspTyr: 1.917 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	4.964GluAla: 4.964 ± 0.079	0.472GluCys: 0.472 ± 0.021	2.239GluAsp: 2.239 ± 0.051	3.186GluGlu: 3.186 ± 0.057	1.775GluPhe: 1.775 ± 0.039	3.488GluGly: 3.488 ± 0.058	1.313GluHis: 1.313 ± 0.034	3.361GluIle: 3.361 ± 0.054	3.287GluLys: 3.287 ± 0.055	5.708GluLeu: 5.708 ± 0.09	1.795GluMet: 1.795 ± 0.037	2.473GluAsn: 2.473 ± 0.048	1.907GluPro: 1.907 ± 0.043	3.374GluGln: 3.374 ± 0.063	3.44GluArg: 3.44 ± 0.06	3.054GluSer: 3.054 ± 0.048	2.809GluThr: 2.809 ± 0.052	3.72GluVal: 3.72 ± 0.057	0.739GluTrp: 0.739 ± 0.023	1.359GluTyr: 1.359 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.589PheAla: 3.589 ± 0.058	0.559PheCys: 0.559 ± 0.023	2.338PheAsp: 2.338 ± 0.044	1.613PheGlu: 1.613 ± 0.038	1.717PhePhe: 1.717 ± 0.045	2.934PheGly: 2.934 ± 0.052	0.849PheHis: 0.849 ± 0.025	2.583PheIle: 2.583 ± 0.046	1.234PheLys: 1.234 ± 0.032	3.335PheLeu: 3.335 ± 0.06	0.937PheMet: 0.937 ± 0.03	1.742PheAsn: 1.742 ± 0.04	1.552PhePro: 1.552 ± 0.041	1.215PheGln: 1.215 ± 0.033	2.121PheArg: 2.121 ± 0.043	3.542PheSer: 3.542 ± 0.058	2.296PheThr: 2.296 ± 0.044	2.312PheVal: 2.312 ± 0.047	0.624PheTrp: 0.624 ± 0.026	1.253PheTyr: 1.253 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	5.91GlyAla: 5.91 ± 0.081	1.012GlyCys: 1.012 ± 0.028	3.601GlyAsp: 3.601 ± 0.063	4.547GlyGlu: 4.547 ± 0.072	3.167GlyPhe: 3.167 ± 0.054	5.273GlyGly: 5.273 ± 0.097	1.7GlyHis: 1.7 ± 0.035	4.731GlyIle: 4.731 ± 0.068	3.798GlyLys: 3.798 ± 0.068	7.326GlyLeu: 7.326 ± 0.085	2.299GlyMet: 2.299 ± 0.045	2.848GlyAsn: 2.848 ± 0.051	1.995GlyPro: 1.995 ± 0.037	3.073GlyGln: 3.073 ± 0.052	4.053GlyArg: 4.053 ± 0.06	4.546GlySer: 4.546 ± 0.073	3.697GlyThr: 3.697 ± 0.062	5.474GlyVal: 5.474 ± 0.07	1.33GlyTrp: 1.33 ± 0.038	2.568GlyTyr: 2.568 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.877HisAla: 1.877 ± 0.036	0.346HisCys: 0.346 ± 0.014	1.176HisAsp: 1.176 ± 0.026	0.981HisGlu: 0.981 ± 0.033	1.121HisPhe: 1.121 ± 0.028	1.712HisGly: 1.712 ± 0.038	0.805HisHis: 0.805 ± 0.024	1.293HisIle: 1.293 ± 0.037	0.716HisLys: 0.716 ± 0.022	2.453HisLeu: 2.453 ± 0.053	0.499HisMet: 0.499 ± 0.021	0.861HisAsn: 0.861 ± 0.028	1.388HisPro: 1.388 ± 0.036	1.461HisGln: 1.461 ± 0.033	1.383HisArg: 1.383 ± 0.04	1.374HisSer: 1.374 ± 0.037	1.074HisThr: 1.074 ± 0.031	1.155HisVal: 1.155 ± 0.033	0.427HisTrp: 0.427 ± 0.019	0.977HisTyr: 0.977 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.202IleAla: 6.202 ± 0.082	0.7IleCys: 0.7 ± 0.023	3.317IleAsp: 3.317 ± 0.057	3.021IleGlu: 3.021 ± 0.061	2.056IlePhe: 2.056 ± 0.043	4.064IleGly: 4.064 ± 0.074	1.168IleHis: 1.168 ± 0.039	3.253IleIle: 3.253 ± 0.06	2.394IleLys: 2.394 ± 0.05	4.813IleLeu: 4.813 ± 0.073	1.213IleMet: 1.213 ± 0.032	2.673IleAsn: 2.673 ± 0.055	2.608IlePro: 2.608 ± 0.046	1.787IleGln: 1.787 ± 0.037	3.094IleArg: 3.094 ± 0.052	4.07IleSer: 4.07 ± 0.067	3.555IleThr: 3.555 ± 0.054	3.653IleVal: 3.653 ± 0.053	0.696IleTrp: 0.696 ± 0.025	1.531IleTyr: 1.531 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	3.852LysAla: 3.852 ± 0.069	0.249LysCys: 0.249 ± 0.016	1.983LysAsp: 1.983 ± 0.043	2.31LysGlu: 2.31 ± 0.049	1.168LysPhe: 1.168 ± 0.033	2.801LysGly: 2.801 ± 0.05	0.786LysHis: 0.786 ± 0.027	2.49LysIle: 2.49 ± 0.055	2.443LysLys: 2.443 ± 0.061	4.062LysLeu: 4.062 ± 0.058	1.269LysMet: 1.269 ± 0.027	2.02LysAsn: 2.02 ± 0.053	1.971LysPro: 1.971 ± 0.041	1.873LysGln: 1.873 ± 0.048	2.275LysArg: 2.275 ± 0.048	2.495LysSer: 2.495 ± 0.052	2.461LysThr: 2.461 ± 0.043	2.823LysVal: 2.823 ± 0.048	0.448LysTrp: 0.448 ± 0.019	1.121LysTyr: 1.121 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	11.569LeuAla: 11.569 ± 0.118	1.294LeuCys: 1.294 ± 0.035	5.282LeuAsp: 5.282 ± 0.081	5.114LeuGlu: 5.114 ± 0.073	4.27LeuPhe: 4.27 ± 0.065	6.712LeuGly: 6.712 ± 0.088	2.539LeuHis: 2.539 ± 0.049	6.038LeuIle: 6.038 ± 0.081	4.698LeuLys: 4.698 ± 0.069	12.615LeuLeu: 12.615 ± 0.159	2.981LeuMet: 2.981 ± 0.059	4.541LeuAsn: 4.541 ± 0.065	5.936LeuPro: 5.936 ± 0.082	4.599LeuGln: 4.599 ± 0.069	6.332LeuArg: 6.332 ± 0.085	8.37LeuSer: 8.37 ± 0.1	6.537LeuThr: 6.537 ± 0.088	6.987LeuVal: 6.987 ± 0.088	1.405LeuTrp: 1.405 ± 0.038	2.623LeuTyr: 2.623 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.856MetAla: 2.856 ± 0.048	0.178MetCys: 0.178 ± 0.013	1.139MetAsp: 1.139 ± 0.031	1.18MetGlu: 1.18 ± 0.029	0.797MetPhe: 0.797 ± 0.027	1.705MetGly: 1.705 ± 0.039	0.517MetHis: 0.517 ± 0.021	1.439MetIle: 1.439 ± 0.039	1.367MetLys: 1.367 ± 0.031	3.183MetLeu: 3.183 ± 0.057	0.872MetMet: 0.872 ± 0.027	1.087MetAsn: 1.087 ± 0.029	1.332MetPro: 1.332 ± 0.03	1.293MetGln: 1.293 ± 0.033	1.48MetArg: 1.48 ± 0.035	1.881MetSer: 1.881 ± 0.04	1.696MetThr: 1.696 ± 0.04	1.88MetVal: 1.88 ± 0.04	0.228MetTrp: 0.228 ± 0.013	0.463MetTyr: 0.463 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.518AsnAla: 3.518 ± 0.054	0.368AsnCys: 0.368 ± 0.018	1.989AsnAsp: 1.989 ± 0.04	1.863AsnGlu: 1.863 ± 0.044	1.366AsnPhe: 1.366 ± 0.035	3.028AsnGly: 3.028 ± 0.058	0.903AsnHis: 0.903 ± 0.027	2.387AsnIle: 2.387 ± 0.044	1.673AsnLys: 1.673 ± 0.043	3.677AsnLeu: 3.677 ± 0.06	0.901AsnMet: 0.901 ± 0.027	1.747AsnAsn: 1.747 ± 0.049	2.028AsnPro: 2.028 ± 0.046	1.771AsnGln: 1.771 ± 0.043	2.13AsnArg: 2.13 ± 0.043	2.318AsnSer: 2.318 ± 0.055	1.929AsnThr: 1.929 ± 0.042	2.392AsnVal: 2.392 ± 0.047	0.559AsnTrp: 0.559 ± 0.02	1.153AsnTyr: 1.153 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	4.77ProAla: 4.77 ± 0.071	0.408ProCys: 0.408 ± 0.019	2.971ProAsp: 2.971 ± 0.057	3.33ProGlu: 3.33 ± 0.053	1.785ProPhe: 1.785 ± 0.038	3.666ProGly: 3.666 ± 0.062	1.054ProHis: 1.054 ± 0.029	1.407ProIle: 1.407 ± 0.036	1.273ProLys: 1.273 ± 0.033	5.247ProLeu: 5.247 ± 0.076	0.954ProMet: 0.954 ± 0.029	1.027ProAsn: 1.027 ± 0.027	1.737ProPro: 1.737 ± 0.049	2.512ProGln: 2.512 ± 0.054	1.905ProArg: 1.905 ± 0.042	2.112ProSer: 2.112 ± 0.041	2.049ProThr: 2.049 ± 0.04	4.216ProVal: 4.216 ± 0.056	0.761ProTrp: 0.761 ± 0.028	1.109ProTyr: 1.109 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	4.862GlnAla: 4.862 ± 0.078	0.361GlnCys: 0.361 ± 0.019	1.956GlnAsp: 1.956 ± 0.043	2.039GlnGlu: 2.039 ± 0.044	1.525GlnPhe: 1.525 ± 0.034	3.196GlnGly: 3.196 ± 0.053	1.434GlnHis: 1.434 ± 0.038	2.366GlnIle: 2.366 ± 0.042	1.779GlnLys: 1.779 ± 0.036	5.582GlnLeu: 5.582 ± 0.08	1.294GlnMet: 1.294 ± 0.031	1.62GlnAsn: 1.62 ± 0.041	2.612GlnPro: 2.612 ± 0.055	4.349GlnGln: 4.349 ± 0.108	3.381GlnArg: 3.381 ± 0.06	2.636GlnSer: 2.636 ± 0.05	2.305GlnThr: 2.305 ± 0.045	3.097GlnVal: 3.097 ± 0.051	0.731GlnTrp: 0.731 ± 0.025	1.169GlnTyr: 1.169 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	4.666ArgAla: 4.666 ± 0.07	0.624ArgCys: 0.624 ± 0.024	2.951ArgAsp: 2.951 ± 0.058	3.607ArgGlu: 3.607 ± 0.058	2.639ArgPhe: 2.639 ± 0.048	3.419ArgGly: 3.419 ± 0.052	1.709ArgHis: 1.709 ± 0.041	3.318ArgIle: 3.318 ± 0.065	2.361ArgLys: 2.361 ± 0.043	6.908ArgLeu: 6.908 ± 0.085	1.548ArgMet: 1.548 ± 0.039	2.122ArgAsn: 2.122 ± 0.038	2.38ArgPro: 2.38 ± 0.047	3.697ArgGln: 3.697 ± 0.053	3.708ArgArg: 3.708 ± 0.073	2.994ArgSer: 2.994 ± 0.051	2.563ArgThr: 2.563 ± 0.047	3.856ArgVal: 3.856 ± 0.06	1.023ArgTrp: 1.023 ± 0.034	2.182ArgTyr: 2.182 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.407SerAla: 6.407 ± 0.086	0.638SerCys: 0.638 ± 0.022	3.453SerAsp: 3.453 ± 0.054	3.638SerGlu: 3.638 ± 0.056	2.408SerPhe: 2.408 ± 0.048	5.842SerGly: 5.842 ± 0.085	1.53SerHis: 1.53 ± 0.032	2.755SerIle: 2.755 ± 0.05	2.098SerLys: 2.098 ± 0.046	7.635SerLeu: 7.635 ± 0.085	1.46SerMet: 1.46 ± 0.035	2.089SerAsn: 2.089 ± 0.043	2.823SerPro: 2.823 ± 0.049	2.969SerGln: 2.969 ± 0.053	3.812SerArg: 3.812 ± 0.056	4.196SerSer: 4.196 ± 0.088	3.17SerThr: 3.17 ± 0.056	4.576SerVal: 4.576 ± 0.064	1.157SerTrp: 1.157 ± 0.032	1.725SerTyr: 1.725 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.295ThrAla: 5.295 ± 0.07	0.494ThrCys: 0.494 ± 0.018	2.747ThrAsp: 2.747 ± 0.051	2.684ThrGlu: 2.684 ± 0.048	1.997ThrPhe: 1.997 ± 0.044	4.657ThrGly: 4.657 ± 0.055	1.162ThrHis: 1.162 ± 0.031	2.693ThrIle: 2.693 ± 0.053	1.314ThrLys: 1.314 ± 0.034	7.656ThrLeu: 7.656 ± 0.095	1.052ThrMet: 1.052 ± 0.029	1.431ThrAsn: 1.431 ± 0.04	3.072ThrPro: 3.072 ± 0.054	2.069ThrGln: 2.069 ± 0.044	3.128ThrArg: 3.128 ± 0.053	3.223ThrSer: 3.223 ± 0.067	2.942ThrThr: 2.942 ± 0.053	3.814ThrVal: 3.814 ± 0.063	0.735ThrTrp: 0.735 ± 0.026	1.034ThrTyr: 1.034 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	7.076ValAla: 7.076 ± 0.087	0.75ValCys: 0.75 ± 0.019	3.563ValAsp: 3.563 ± 0.053	3.746ValGlu: 3.746 ± 0.055	2.481ValPhe: 2.481 ± 0.044	4.56ValGly: 4.56 ± 0.067	1.239ValHis: 1.239 ± 0.034	4.372ValIle: 4.372 ± 0.069	2.943ValLys: 2.943 ± 0.063	7.087ValLeu: 7.087 ± 0.084	2.126ValMet: 2.126 ± 0.042	2.695ValAsn: 2.695 ± 0.051	2.926ValPro: 2.926 ± 0.055	2.477ValGln: 2.477 ± 0.045	3.787ValArg: 3.787 ± 0.053	4.953ValSer: 4.953 ± 0.07	4.311ValThr: 4.311 ± 0.065	5.467ValVal: 5.467 ± 0.074	0.965ValTrp: 0.965 ± 0.025	1.574ValTyr: 1.574 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.935TrpAla: 0.935 ± 0.026	0.202TrpCys: 0.202 ± 0.015	0.648TrpAsp: 0.648 ± 0.023	0.538TrpGlu: 0.538 ± 0.021	0.646TrpPhe: 0.646 ± 0.024	0.823TrpGly: 0.823 ± 0.028	0.499TrpHis: 0.499 ± 0.02	0.741TrpIle: 0.741 ± 0.026	0.514TrpLys: 0.514 ± 0.021	2.5TrpLeu: 2.5 ± 0.057	0.443TrpMet: 0.443 ± 0.018	0.474TrpAsn: 0.474 ± 0.022	0.704TrpPro: 0.704 ± 0.025	1.439TrpGln: 1.439 ± 0.039	1.043TrpArg: 1.043 ± 0.03	0.909TrpSer: 0.909 ± 0.03	0.541TrpThr: 0.541 ± 0.022	0.877TrpVal: 0.877 ± 0.024	0.24TrpTrp: 0.24 ± 0.015	0.439TrpTyr: 0.439 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.289TyrAla: 2.289 ± 0.047	0.366TyrCys: 0.366 ± 0.016	1.542TyrAsp: 1.542 ± 0.033	1.15TyrGlu: 1.15 ± 0.032	1.179TyrPhe: 1.179 ± 0.032	2.053TyrGly: 2.053 ± 0.046	0.75TyrHis: 0.75 ± 0.025	1.366TyrIle: 1.366 ± 0.039	0.905TyrLys: 0.905 ± 0.033	3.108TyrLeu: 3.108 ± 0.054	0.54TyrMet: 0.54 ± 0.021	1.003TyrAsn: 1.003 ± 0.029	1.288TyrPro: 1.288 ± 0.039	1.783TyrGln: 1.783 ± 0.042	1.919TyrArg: 1.919 ± 0.037	1.821TyrSer: 1.821 ± 0.044	1.295TyrThr: 1.295 ± 0.032	1.591TyrVal: 1.591 ± 0.039	0.421TyrTrp: 0.421 ± 0.022	0.892TyrTyr: 0.892 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3959 proteins (1244858 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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