Amino acid dipepetide frequency for Staphylococcus virus 29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.577AlaAla: 0.577 ± 0.22
0.289AlaCys: 0.289 ± 0.169
2.02AlaAsp: 2.02 ± 0.338
3.462AlaGlu: 3.462 ± 0.509
2.453AlaPhe: 2.453 ± 0.5
3.895AlaGly: 3.895 ± 0.704
1.154AlaHis: 1.154 ± 0.268
4.761AlaIle: 4.761 ± 0.568
6.564AlaLys: 6.564 ± 0.705
4.472AlaLeu: 4.472 ± 0.565
1.515AlaMet: 1.515 ± 0.357
3.318AlaAsn: 3.318 ± 0.395
2.308AlaPro: 2.308 ± 0.417
2.741AlaGln: 2.741 ± 0.406
2.958AlaArg: 2.958 ± 0.393
3.462AlaSer: 3.462 ± 0.516
4.328AlaThr: 4.328 ± 0.609
4.112AlaVal: 4.112 ± 0.675
0.866AlaTrp: 0.866 ± 0.374
2.236AlaTyr: 2.236 ± 0.44
0.0AlaXaa: 0.0 ± 0.0
Cys
0.289CysAla: 0.289 ± 0.135
0.144CysCys: 0.144 ± 0.084
0.505CysAsp: 0.505 ± 0.199
0.216CysGlu: 0.216 ± 0.109
0.289CysPhe: 0.289 ± 0.139
0.289CysGly: 0.289 ± 0.159
0.072CysHis: 0.072 ± 0.079
0.216CysIle: 0.216 ± 0.118
0.289CysLys: 0.289 ± 0.131
0.289CysLeu: 0.289 ± 0.13
0.144CysMet: 0.144 ± 0.103
0.216CysAsn: 0.216 ± 0.12
0.433CysPro: 0.433 ± 0.216
0.216CysGln: 0.216 ± 0.127
0.505CysArg: 0.505 ± 0.216
0.505CysSer: 0.505 ± 0.192
0.289CysThr: 0.289 ± 0.148
0.361CysVal: 0.361 ± 0.153
0.072CysTrp: 0.072 ± 0.066
0.361CysTyr: 0.361 ± 0.147
0.0CysXaa: 0.0 ± 0.0
Asp
4.184AspAla: 4.184 ± 0.574
0.289AspCys: 0.289 ± 0.13
4.617AspAsp: 4.617 ± 0.763
5.338AspGlu: 5.338 ± 0.732
2.958AspPhe: 2.958 ± 0.501
4.256AspGly: 4.256 ± 0.599
0.433AspHis: 0.433 ± 0.169
4.112AspIle: 4.112 ± 0.591
5.194AspLys: 5.194 ± 0.69
5.049AspLeu: 5.049 ± 0.589
2.164AspMet: 2.164 ± 0.417
3.318AspAsn: 3.318 ± 0.541
1.01AspPro: 1.01 ± 0.279
1.154AspGln: 1.154 ± 0.266
1.875AspArg: 1.875 ± 0.382
3.39AspSer: 3.39 ± 0.498
3.607AspThr: 3.607 ± 0.574
4.112AspVal: 4.112 ± 0.66
0.793AspTrp: 0.793 ± 0.239
2.885AspTyr: 2.885 ± 0.45
0.0AspXaa: 0.0 ± 0.0
Glu
3.462GluAla: 3.462 ± 0.474
0.721GluCys: 0.721 ± 0.232
3.895GluAsp: 3.895 ± 0.628
6.059GluGlu: 6.059 ± 1.17
3.174GluPhe: 3.174 ± 0.497
2.885GluGly: 2.885 ± 0.445
1.226GluHis: 1.226 ± 0.395
5.482GluIle: 5.482 ± 0.678
5.699GluLys: 5.699 ± 1.007
7.574GluLeu: 7.574 ± 0.948
2.02GluMet: 2.02 ± 0.423
4.544GluAsn: 4.544 ± 0.624
2.236GluPro: 2.236 ± 0.337
3.895GluGln: 3.895 ± 0.564
3.462GluArg: 3.462 ± 0.521
3.751GluSer: 3.751 ± 0.539
3.535GluThr: 3.535 ± 0.427
4.905GluVal: 4.905 ± 0.536
0.866GluTrp: 0.866 ± 0.264
3.823GluTyr: 3.823 ± 0.558
0.0GluXaa: 0.0 ± 0.0
Phe
1.803PheAla: 1.803 ± 0.394
0.289PheCys: 0.289 ± 0.111
4.256PheAsp: 4.256 ± 0.432
3.462PheGlu: 3.462 ± 0.536
1.298PhePhe: 1.298 ± 0.343
2.813PheGly: 2.813 ± 0.76
0.577PheHis: 0.577 ± 0.169
3.607PheIle: 3.607 ± 0.58
4.256PheLys: 4.256 ± 0.502
3.102PheLeu: 3.102 ± 0.418
1.226PheMet: 1.226 ± 0.27
2.885PheAsn: 2.885 ± 0.395
0.938PhePro: 0.938 ± 0.313
1.01PheGln: 1.01 ± 0.359
1.226PheArg: 1.226 ± 0.232
2.236PheSer: 2.236 ± 0.396
3.03PheThr: 3.03 ± 0.47
2.813PheVal: 2.813 ± 0.433
0.361PheTrp: 0.361 ± 0.186
1.803PheTyr: 1.803 ± 0.402
0.0PheXaa: 0.0 ± 0.0
Gly
4.112GlyAla: 4.112 ± 0.678
0.361GlyCys: 0.361 ± 0.165
3.318GlyAsp: 3.318 ± 0.499
3.174GlyGlu: 3.174 ± 0.545
2.958GlyPhe: 2.958 ± 0.479
3.174GlyGly: 3.174 ± 0.482
1.443GlyHis: 1.443 ± 0.354
4.256GlyIle: 4.256 ± 0.54
4.833GlyLys: 4.833 ± 0.497
4.544GlyLeu: 4.544 ± 0.664
1.515GlyMet: 1.515 ± 0.395
2.885GlyAsn: 2.885 ± 0.39
0.361GlyPro: 0.361 ± 0.163
2.741GlyGln: 2.741 ± 0.357
2.092GlyArg: 2.092 ± 0.415
2.958GlySer: 2.958 ± 0.513
3.967GlyThr: 3.967 ± 0.643
5.194GlyVal: 5.194 ± 0.864
1.082GlyTrp: 1.082 ± 0.408
3.174GlyTyr: 3.174 ± 0.518
0.0GlyXaa: 0.0 ± 0.0
His
1.226HisAla: 1.226 ± 0.249
0.0HisCys: 0.0 ± 0.0
0.721HisAsp: 0.721 ± 0.241
1.01HisGlu: 1.01 ± 0.298
0.866HisPhe: 0.866 ± 0.23
1.154HisGly: 1.154 ± 0.227
0.505HisHis: 0.505 ± 0.213
1.154HisIle: 1.154 ± 0.231
1.371HisLys: 1.371 ± 0.274
1.587HisLeu: 1.587 ± 0.347
0.216HisMet: 0.216 ± 0.11
1.226HisAsn: 1.226 ± 0.299
0.793HisPro: 0.793 ± 0.279
0.938HisGln: 0.938 ± 0.283
0.721HisArg: 0.721 ± 0.249
1.371HisSer: 1.371 ± 0.303
1.298HisThr: 1.298 ± 0.308
0.793HisVal: 0.793 ± 0.236
0.072HisTrp: 0.072 ± 0.07
0.866HisTyr: 0.866 ± 0.382
0.0HisXaa: 0.0 ± 0.0
Ile
4.905IleAla: 4.905 ± 0.629
0.361IleCys: 0.361 ± 0.16
4.977IleAsp: 4.977 ± 0.593
6.492IleGlu: 6.492 ± 0.821
2.885IlePhe: 2.885 ± 0.455
5.122IleGly: 5.122 ± 0.645
1.01IleHis: 1.01 ± 0.267
4.4IleIle: 4.4 ± 0.58
8.007IleLys: 8.007 ± 0.758
3.895IleLeu: 3.895 ± 0.566
2.597IleMet: 2.597 ± 0.381
4.544IleAsn: 4.544 ± 0.678
2.236IlePro: 2.236 ± 0.385
2.885IleGln: 2.885 ± 0.467
3.39IleArg: 3.39 ± 0.509
4.04IleSer: 4.04 ± 0.562
5.338IleThr: 5.338 ± 0.57
3.967IleVal: 3.967 ± 0.545
1.01IleTrp: 1.01 ± 0.374
2.669IleTyr: 2.669 ± 0.554
0.0IleXaa: 0.0 ± 0.0
Lys
4.977LysAla: 4.977 ± 0.487
0.144LysCys: 0.144 ± 0.093
5.987LysAsp: 5.987 ± 0.714
7.718LysGlu: 7.718 ± 0.704
3.462LysPhe: 3.462 ± 0.534
5.049LysGly: 5.049 ± 0.496
2.092LysHis: 2.092 ± 0.374
7.141LysIle: 7.141 ± 1.052
7.286LysLys: 7.286 ± 0.923
6.925LysLeu: 6.925 ± 0.66
2.236LysMet: 2.236 ± 0.34
4.977LysAsn: 4.977 ± 0.649
2.669LysPro: 2.669 ± 0.529
3.679LysGln: 3.679 ± 0.475
4.4LysArg: 4.4 ± 0.538
4.761LysSer: 4.761 ± 0.501
6.276LysThr: 6.276 ± 0.664
5.194LysVal: 5.194 ± 0.636
0.793LysTrp: 0.793 ± 0.23
3.895LysTyr: 3.895 ± 0.555
0.0LysXaa: 0.0 ± 0.0
Leu
4.617LeuAla: 4.617 ± 0.617
0.505LeuCys: 0.505 ± 0.255
4.617LeuAsp: 4.617 ± 0.673
5.122LeuGlu: 5.122 ± 0.875
3.823LeuPhe: 3.823 ± 0.478
3.535LeuGly: 3.535 ± 0.561
1.515LeuHis: 1.515 ± 0.361
4.833LeuIle: 4.833 ± 0.442
7.935LeuLys: 7.935 ± 0.719
5.626LeuLeu: 5.626 ± 0.745
1.948LeuMet: 1.948 ± 0.486
5.122LeuAsn: 5.122 ± 0.554
2.453LeuPro: 2.453 ± 0.465
3.318LeuGln: 3.318 ± 0.444
3.102LeuArg: 3.102 ± 0.568
5.266LeuSer: 5.266 ± 0.509
5.843LeuThr: 5.843 ± 0.738
4.472LeuVal: 4.472 ± 0.713
0.649LeuTrp: 0.649 ± 0.252
3.318LeuTyr: 3.318 ± 0.558
0.0LeuXaa: 0.0 ± 0.0
Met
1.443MetAla: 1.443 ± 0.568
0.144MetCys: 0.144 ± 0.096
1.298MetAsp: 1.298 ± 0.347
1.659MetGlu: 1.659 ± 0.326
1.371MetPhe: 1.371 ± 0.3
0.938MetGly: 0.938 ± 0.287
0.289MetHis: 0.289 ± 0.161
1.731MetIle: 1.731 ± 0.334
2.02MetLys: 2.02 ± 0.385
2.885MetLeu: 2.885 ± 0.42
0.866MetMet: 0.866 ± 0.298
2.092MetAsn: 2.092 ± 0.427
1.154MetPro: 1.154 ± 0.26
1.803MetGln: 1.803 ± 0.47
1.154MetArg: 1.154 ± 0.265
1.515MetSer: 1.515 ± 0.424
1.803MetThr: 1.803 ± 0.429
0.938MetVal: 0.938 ± 0.225
0.577MetTrp: 0.577 ± 0.222
1.298MetTyr: 1.298 ± 0.3
0.0MetXaa: 0.0 ± 0.0
Asn
4.112AsnAla: 4.112 ± 0.541
0.289AsnCys: 0.289 ± 0.143
4.184AsnAsp: 4.184 ± 0.484
4.544AsnGlu: 4.544 ± 0.477
2.38AsnPhe: 2.38 ± 0.428
4.544AsnGly: 4.544 ± 0.6
0.721AsnHis: 0.721 ± 0.218
4.977AsnIle: 4.977 ± 0.568
6.059AsnLys: 6.059 ± 0.712
4.184AsnLeu: 4.184 ± 0.729
1.803AsnMet: 1.803 ± 0.336
4.184AsnAsn: 4.184 ± 0.605
2.885AsnPro: 2.885 ± 0.45
1.948AsnGln: 1.948 ± 0.355
2.236AsnArg: 2.236 ± 0.383
2.813AsnSer: 2.813 ± 0.363
4.04AsnThr: 4.04 ± 0.514
3.246AsnVal: 3.246 ± 0.504
0.793AsnTrp: 0.793 ± 0.217
2.741AsnTyr: 2.741 ± 0.471
0.0AsnXaa: 0.0 ± 0.0
Pro
1.371ProAla: 1.371 ± 0.294
0.216ProCys: 0.216 ± 0.122
1.443ProAsp: 1.443 ± 0.318
2.092ProGlu: 2.092 ± 0.408
1.443ProPhe: 1.443 ± 0.352
1.587ProGly: 1.587 ± 0.395
0.577ProHis: 0.577 ± 0.2
2.38ProIle: 2.38 ± 0.434
3.246ProLys: 3.246 ± 0.502
1.443ProLeu: 1.443 ± 0.273
0.721ProMet: 0.721 ± 0.233
2.236ProAsn: 2.236 ± 0.473
0.649ProPro: 0.649 ± 0.222
1.082ProGln: 1.082 ± 0.246
0.938ProArg: 0.938 ± 0.186
2.741ProSer: 2.741 ± 0.535
2.164ProThr: 2.164 ± 0.307
2.02ProVal: 2.02 ± 0.384
0.144ProTrp: 0.144 ± 0.105
1.587ProTyr: 1.587 ± 0.338
0.0ProXaa: 0.0 ± 0.0
Gln
4.256GlnAla: 4.256 ± 0.496
0.433GlnCys: 0.433 ± 0.172
1.443GlnAsp: 1.443 ± 0.338
3.102GlnGlu: 3.102 ± 0.581
2.236GlnPhe: 2.236 ± 0.358
2.164GlnGly: 2.164 ± 0.459
1.01GlnHis: 1.01 ± 0.23
3.246GlnIle: 3.246 ± 0.419
1.875GlnLys: 1.875 ± 0.369
3.174GlnLeu: 3.174 ± 0.374
1.226GlnMet: 1.226 ± 0.305
2.453GlnAsn: 2.453 ± 0.354
1.515GlnPro: 1.515 ± 0.425
2.38GlnGln: 2.38 ± 0.48
1.587GlnArg: 1.587 ± 0.356
1.803GlnSer: 1.803 ± 0.335
1.875GlnThr: 1.875 ± 0.323
2.813GlnVal: 2.813 ± 0.523
0.216GlnTrp: 0.216 ± 0.113
1.371GlnTyr: 1.371 ± 0.369
0.0GlnXaa: 0.0 ± 0.0
Arg
1.659ArgAla: 1.659 ± 0.355
0.433ArgCys: 0.433 ± 0.18
2.741ArgAsp: 2.741 ± 0.431
3.174ArgGlu: 3.174 ± 0.552
2.02ArgPhe: 2.02 ± 0.342
1.948ArgGly: 1.948 ± 0.376
1.298ArgHis: 1.298 ± 0.279
3.102ArgIle: 3.102 ± 0.508
3.535ArgLys: 3.535 ± 0.534
4.04ArgLeu: 4.04 ± 0.614
0.866ArgMet: 0.866 ± 0.188
2.597ArgAsn: 2.597 ± 0.404
1.082ArgPro: 1.082 ± 0.231
2.236ArgGln: 2.236 ± 0.415
1.082ArgArg: 1.082 ± 0.313
1.948ArgSer: 1.948 ± 0.361
1.371ArgThr: 1.371 ± 0.362
2.02ArgVal: 2.02 ± 0.343
0.361ArgTrp: 0.361 ± 0.175
2.525ArgTyr: 2.525 ± 0.396
0.0ArgXaa: 0.0 ± 0.0
Ser
3.967SerAla: 3.967 ± 0.608
0.216SerCys: 0.216 ± 0.162
3.967SerAsp: 3.967 ± 0.551
3.03SerGlu: 3.03 ± 0.47
2.38SerPhe: 2.38 ± 0.516
3.751SerGly: 3.751 ± 0.668
1.01SerHis: 1.01 ± 0.215
5.194SerIle: 5.194 ± 0.712
4.761SerLys: 4.761 ± 0.637
3.679SerLeu: 3.679 ± 0.525
2.02SerMet: 2.02 ± 0.299
4.617SerAsn: 4.617 ± 0.555
1.515SerPro: 1.515 ± 0.383
2.525SerGln: 2.525 ± 0.488
2.164SerArg: 2.164 ± 0.312
3.535SerSer: 3.535 ± 0.598
3.462SerThr: 3.462 ± 0.423
3.823SerVal: 3.823 ± 0.625
0.577SerTrp: 0.577 ± 0.188
1.731SerTyr: 1.731 ± 0.304
0.0SerXaa: 0.0 ± 0.0
Thr
3.895ThrAla: 3.895 ± 0.615
0.216ThrCys: 0.216 ± 0.126
3.679ThrAsp: 3.679 ± 0.46
4.472ThrGlu: 4.472 ± 0.558
2.525ThrPhe: 2.525 ± 0.48
4.112ThrGly: 4.112 ± 0.708
1.443ThrHis: 1.443 ± 0.329
4.977ThrIle: 4.977 ± 0.711
4.833ThrLys: 4.833 ± 0.706
5.987ThrLeu: 5.987 ± 0.738
0.721ThrMet: 0.721 ± 0.206
4.184ThrAsn: 4.184 ± 0.586
2.164ThrPro: 2.164 ± 0.355
2.308ThrGln: 2.308 ± 0.447
2.453ThrArg: 2.453 ± 0.398
4.617ThrSer: 4.617 ± 0.867
4.184ThrThr: 4.184 ± 0.555
4.4ThrVal: 4.4 ± 0.588
0.866ThrTrp: 0.866 ± 0.283
2.453ThrTyr: 2.453 ± 0.411
0.0ThrXaa: 0.0 ± 0.0
Val
4.544ValAla: 4.544 ± 0.68
0.216ValCys: 0.216 ± 0.118
4.833ValAsp: 4.833 ± 0.771
5.266ValGlu: 5.266 ± 0.579
2.236ValPhe: 2.236 ± 0.369
3.462ValGly: 3.462 ± 0.532
0.216ValHis: 0.216 ± 0.11
4.905ValIle: 4.905 ± 0.589
6.492ValLys: 6.492 ± 0.657
4.761ValLeu: 4.761 ± 0.562
1.948ValMet: 1.948 ± 0.356
3.39ValAsn: 3.39 ± 0.453
2.236ValPro: 2.236 ± 0.365
0.721ValGln: 0.721 ± 0.268
2.092ValArg: 2.092 ± 0.382
4.04ValSer: 4.04 ± 0.593
4.328ValThr: 4.328 ± 0.702
4.761ValVal: 4.761 ± 0.719
0.866ValTrp: 0.866 ± 0.265
2.597ValTyr: 2.597 ± 0.424
0.0ValXaa: 0.0 ± 0.0
Trp
0.649TrpAla: 0.649 ± 0.205
0.072TrpCys: 0.072 ± 0.066
0.289TrpAsp: 0.289 ± 0.123
1.01TrpGlu: 1.01 ± 0.255
0.505TrpPhe: 0.505 ± 0.158
1.082TrpGly: 1.082 ± 0.285
0.289TrpHis: 0.289 ± 0.124
0.866TrpIle: 0.866 ± 0.264
1.154TrpLys: 1.154 ± 0.292
0.866TrpLeu: 0.866 ± 0.285
0.144TrpMet: 0.144 ± 0.109
0.721TrpAsn: 0.721 ± 0.236
0.072TrpPro: 0.072 ± 0.071
0.649TrpGln: 0.649 ± 0.219
0.289TrpArg: 0.289 ± 0.154
0.649TrpSer: 0.649 ± 0.257
0.938TrpThr: 0.938 ± 0.199
0.866TrpVal: 0.866 ± 0.271
0.0TrpTrp: 0.0 ± 0.0
0.505TrpTyr: 0.505 ± 0.196
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.443TyrAla: 1.443 ± 0.355
0.361TyrCys: 0.361 ± 0.171
2.02TyrAsp: 2.02 ± 0.478
2.813TyrGlu: 2.813 ± 0.481
1.731TyrPhe: 1.731 ± 0.481
2.38TyrGly: 2.38 ± 0.455
1.01TyrHis: 1.01 ± 0.28
3.39TyrIle: 3.39 ± 0.508
4.256TyrLys: 4.256 ± 0.616
3.535TyrLeu: 3.535 ± 0.458
1.01TyrMet: 1.01 ± 0.255
3.174TyrAsn: 3.174 ± 0.486
1.371TyrPro: 1.371 ± 0.327
1.948TyrGln: 1.948 ± 0.344
2.308TyrArg: 2.308 ± 0.469
2.525TyrSer: 2.525 ± 0.508
2.813TyrThr: 2.813 ± 0.414
3.102TyrVal: 3.102 ± 0.447
0.649TyrTrp: 0.649 ± 0.205
2.092TyrTyr: 2.092 ± 0.47
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 75 proteins (13864 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski