Amino acid dipepetide frequency for Rotavirus A pheasant-tc/GER/10V0112H5/2010/G23P[37]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.344AlaAla: 4.344 ± 0.742
0.835AlaCys: 0.835 ± 0.32
2.339AlaAsp: 2.339 ± 0.519
2.005AlaGlu: 2.005 ± 0.542
2.673AlaPhe: 2.673 ± 0.461
2.172AlaGly: 2.172 ± 0.525
0.835AlaHis: 0.835 ± 0.31
3.342AlaIle: 3.342 ± 0.851
4.511AlaLys: 4.511 ± 0.983
4.845AlaLeu: 4.845 ± 0.767
1.838AlaMet: 1.838 ± 0.463
4.678AlaAsn: 4.678 ± 0.655
1.671AlaPro: 1.671 ± 0.786
1.504AlaGln: 1.504 ± 0.594
2.84AlaArg: 2.84 ± 1.03
4.344AlaSer: 4.344 ± 0.915
3.008AlaThr: 3.008 ± 0.575
4.511AlaVal: 4.511 ± 0.782
0.167AlaTrp: 0.167 ± 0.204
1.504AlaTyr: 1.504 ± 0.425
0.0AlaXaa: 0.0 ± 0.0
Cys
0.668CysAla: 0.668 ± 0.314
0.668CysCys: 0.668 ± 0.366
0.668CysAsp: 0.668 ± 0.265
0.501CysGlu: 0.501 ± 0.37
0.668CysPhe: 0.668 ± 0.406
0.501CysGly: 0.501 ± 0.258
0.167CysHis: 0.167 ± 0.151
1.17CysIle: 1.17 ± 0.449
0.835CysLys: 0.835 ± 0.382
0.334CysLeu: 0.334 ± 0.28
0.501CysMet: 0.501 ± 0.306
1.003CysAsn: 1.003 ± 0.478
0.668CysPro: 0.668 ± 0.532
0.668CysGln: 0.668 ± 0.265
0.668CysArg: 0.668 ± 0.579
0.334CysSer: 0.334 ± 0.242
1.17CysThr: 1.17 ± 0.653
0.668CysVal: 0.668 ± 0.305
0.167CysTrp: 0.167 ± 0.17
0.835CysTyr: 0.835 ± 0.224
0.0CysXaa: 0.0 ± 0.0
Asp
3.509AspAla: 3.509 ± 0.714
0.668AspCys: 0.668 ± 0.431
4.845AspAsp: 4.845 ± 0.795
3.008AspGlu: 3.008 ± 0.603
3.843AspPhe: 3.843 ± 0.766
2.673AspGly: 2.673 ± 0.603
0.501AspHis: 0.501 ± 0.293
5.013AspIle: 5.013 ± 0.861
3.008AspLys: 3.008 ± 0.866
5.18AspLeu: 5.18 ± 1.145
1.337AspMet: 1.337 ± 0.565
2.673AspAsn: 2.673 ± 0.531
3.008AspPro: 3.008 ± 0.624
2.84AspGln: 2.84 ± 0.607
1.504AspArg: 1.504 ± 0.43
5.18AspSer: 5.18 ± 0.611
4.01AspThr: 4.01 ± 0.98
4.678AspVal: 4.678 ± 0.867
0.334AspTrp: 0.334 ± 0.263
4.344AspTyr: 4.344 ± 0.747
0.0AspXaa: 0.0 ± 0.0
Glu
1.337GluAla: 1.337 ± 0.382
0.501GluCys: 0.501 ± 0.3
2.506GluAsp: 2.506 ± 1.006
2.84GluGlu: 2.84 ± 0.806
3.008GluPhe: 3.008 ± 0.672
1.504GluGly: 1.504 ± 0.397
0.835GluHis: 0.835 ± 0.373
4.344GluIle: 4.344 ± 1.028
4.511GluLys: 4.511 ± 0.894
6.015GluLeu: 6.015 ± 1.078
2.005GluMet: 2.005 ± 0.38
2.673GluAsn: 2.673 ± 0.658
1.671GluPro: 1.671 ± 0.645
1.838GluGln: 1.838 ± 0.759
2.339GluArg: 2.339 ± 0.779
4.01GluSer: 4.01 ± 1.229
3.342GluThr: 3.342 ± 0.88
3.008GluVal: 3.008 ± 0.661
0.835GluTrp: 0.835 ± 0.48
4.678GluTyr: 4.678 ± 0.758
0.0GluXaa: 0.0 ± 0.0
Phe
2.172PheAla: 2.172 ± 0.645
0.501PheCys: 0.501 ± 0.225
3.676PheAsp: 3.676 ± 0.778
2.172PheGlu: 2.172 ± 0.683
0.835PhePhe: 0.835 ± 0.313
2.005PheGly: 2.005 ± 0.518
1.671PheHis: 1.671 ± 0.516
3.008PheIle: 3.008 ± 0.74
4.511PheLys: 4.511 ± 0.826
2.506PheLeu: 2.506 ± 0.593
0.835PheMet: 0.835 ± 0.3
3.342PheAsn: 3.342 ± 0.615
1.17PhePro: 1.17 ± 0.612
1.838PheGln: 1.838 ± 0.544
2.172PheArg: 2.172 ± 0.546
3.509PheSer: 3.509 ± 0.861
2.339PheThr: 2.339 ± 0.794
2.005PheVal: 2.005 ± 0.668
0.501PheTrp: 0.501 ± 0.207
1.504PheTyr: 1.504 ± 0.595
0.0PheXaa: 0.0 ± 0.0
Gly
0.835GlyAla: 0.835 ± 0.191
0.334GlyCys: 0.334 ± 0.233
1.504GlyAsp: 1.504 ± 0.532
1.504GlyGlu: 1.504 ± 0.467
1.17GlyPhe: 1.17 ± 0.463
1.671GlyGly: 1.671 ± 0.621
0.835GlyHis: 0.835 ± 0.43
3.676GlyIle: 3.676 ± 0.366
2.506GlyLys: 2.506 ± 0.584
3.008GlyLeu: 3.008 ± 0.62
0.835GlyMet: 0.835 ± 0.679
2.339GlyAsn: 2.339 ± 0.442
1.17GlyPro: 1.17 ± 0.521
1.504GlyGln: 1.504 ± 0.4
1.17GlyArg: 1.17 ± 0.316
2.339GlySer: 2.339 ± 0.712
2.673GlyThr: 2.673 ± 1.01
3.175GlyVal: 3.175 ± 0.387
0.334GlyTrp: 0.334 ± 0.23
1.17GlyTyr: 1.17 ± 0.477
0.0GlyXaa: 0.0 ± 0.0
His
1.337HisAla: 1.337 ± 0.474
0.0HisCys: 0.0 ± 0.0
2.005HisAsp: 2.005 ± 0.598
0.835HisGlu: 0.835 ± 0.413
0.501HisPhe: 0.501 ± 0.23
0.334HisGly: 0.334 ± 0.224
0.334HisHis: 0.334 ± 0.237
1.17HisIle: 1.17 ± 0.33
0.501HisLys: 0.501 ± 0.3
1.671HisLeu: 1.671 ± 0.571
0.501HisMet: 0.501 ± 0.252
1.671HisAsn: 1.671 ± 0.437
0.501HisPro: 0.501 ± 0.216
0.334HisGln: 0.334 ± 0.213
0.334HisArg: 0.334 ± 0.206
0.501HisSer: 0.501 ± 0.334
0.835HisThr: 0.835 ± 0.363
1.003HisVal: 1.003 ± 0.267
0.167HisTrp: 0.167 ± 0.159
1.17HisTyr: 1.17 ± 0.573
0.0HisXaa: 0.0 ± 0.0
Ile
5.681IleAla: 5.681 ± 1.102
1.003IleCys: 1.003 ± 0.508
6.182IleAsp: 6.182 ± 1.087
4.845IleGlu: 4.845 ± 1.255
2.673IlePhe: 2.673 ± 0.75
2.172IleGly: 2.172 ± 0.633
0.334IleHis: 0.334 ± 0.169
5.347IleIle: 5.347 ± 1.299
5.18IleLys: 5.18 ± 0.865
7.018IleLeu: 7.018 ± 0.884
1.504IleMet: 1.504 ± 0.494
7.018IleAsn: 7.018 ± 0.894
3.008IlePro: 3.008 ± 0.836
2.673IleGln: 2.673 ± 0.551
4.01IleArg: 4.01 ± 0.645
4.845IleSer: 4.845 ± 0.923
5.514IleThr: 5.514 ± 0.726
4.511IleVal: 4.511 ± 0.752
0.501IleTrp: 0.501 ± 0.292
2.84IleTyr: 2.84 ± 0.716
0.0IleXaa: 0.0 ± 0.0
Lys
3.175LysAla: 3.175 ± 0.718
0.501LysCys: 0.501 ± 0.319
3.175LysAsp: 3.175 ± 0.608
4.177LysGlu: 4.177 ± 0.951
3.843LysPhe: 3.843 ± 1.019
2.172LysGly: 2.172 ± 0.436
0.835LysHis: 0.835 ± 0.313
5.347LysIle: 5.347 ± 1.241
4.511LysLys: 4.511 ± 1.085
7.686LysLeu: 7.686 ± 1.156
2.84LysMet: 2.84 ± 0.861
2.172LysAsn: 2.172 ± 0.564
2.339LysPro: 2.339 ± 0.606
2.506LysGln: 2.506 ± 0.62
3.175LysArg: 3.175 ± 0.601
6.349LysSer: 6.349 ± 1.571
3.509LysThr: 3.509 ± 0.585
4.511LysVal: 4.511 ± 0.8
1.504LysTrp: 1.504 ± 0.503
3.676LysTyr: 3.676 ± 0.972
0.0LysXaa: 0.0 ± 0.0
Leu
5.013LeuAla: 5.013 ± 1.122
1.17LeuCys: 1.17 ± 0.675
5.681LeuAsp: 5.681 ± 0.994
3.843LeuGlu: 3.843 ± 0.892
3.175LeuPhe: 3.175 ± 0.402
1.671LeuGly: 1.671 ± 0.418
2.172LeuHis: 2.172 ± 0.692
6.516LeuIle: 6.516 ± 0.968
4.511LeuLys: 4.511 ± 1.114
9.524LeuLeu: 9.524 ± 0.888
2.84LeuMet: 2.84 ± 0.81
6.85LeuAsn: 6.85 ± 1.213
4.678LeuPro: 4.678 ± 0.982
4.01LeuGln: 4.01 ± 0.696
4.845LeuArg: 4.845 ± 0.781
9.023LeuSer: 9.023 ± 1.542
7.352LeuThr: 7.352 ± 1.238
5.347LeuVal: 5.347 ± 0.851
0.835LeuTrp: 0.835 ± 0.339
5.18LeuTyr: 5.18 ± 0.994
0.0LeuXaa: 0.0 ± 0.0
Met
1.671MetAla: 1.671 ± 0.361
0.501MetCys: 0.501 ± 0.199
1.671MetAsp: 1.671 ± 0.446
1.17MetGlu: 1.17 ± 0.42
1.17MetPhe: 1.17 ± 0.592
0.835MetGly: 0.835 ± 0.332
0.835MetHis: 0.835 ± 0.3
1.17MetIle: 1.17 ± 0.268
2.506MetLys: 2.506 ± 0.617
3.676MetLeu: 3.676 ± 0.854
0.167MetMet: 0.167 ± 0.248
1.838MetAsn: 1.838 ± 0.502
0.501MetPro: 0.501 ± 0.224
1.504MetGln: 1.504 ± 0.628
0.835MetArg: 0.835 ± 0.409
2.673MetSer: 2.673 ± 0.752
1.504MetThr: 1.504 ± 0.628
1.17MetVal: 1.17 ± 0.807
0.501MetTrp: 0.501 ± 0.224
1.337MetTyr: 1.337 ± 0.402
0.0MetXaa: 0.0 ± 0.0
Asn
4.344AsnAla: 4.344 ± 0.714
0.835AsnCys: 0.835 ± 0.491
4.678AsnAsp: 4.678 ± 0.667
3.509AsnGlu: 3.509 ± 0.446
2.005AsnPhe: 2.005 ± 0.473
3.008AsnGly: 3.008 ± 0.792
2.005AsnHis: 2.005 ± 0.682
3.843AsnIle: 3.843 ± 0.996
3.676AsnLys: 3.676 ± 1.018
6.516AsnLeu: 6.516 ± 0.84
2.172AsnMet: 2.172 ± 0.472
3.843AsnAsn: 3.843 ± 0.954
1.671AsnPro: 1.671 ± 0.721
3.509AsnGln: 3.509 ± 1.003
2.84AsnArg: 2.84 ± 0.521
5.848AsnSer: 5.848 ± 0.789
3.676AsnThr: 3.676 ± 0.606
4.678AsnVal: 4.678 ± 0.825
1.838AsnTrp: 1.838 ± 0.584
4.177AsnTyr: 4.177 ± 0.911
0.0AsnXaa: 0.0 ± 0.0
Pro
1.337ProAla: 1.337 ± 0.466
0.167ProCys: 0.167 ± 0.163
1.17ProAsp: 1.17 ± 0.74
2.339ProGlu: 2.339 ± 0.451
2.172ProPhe: 2.172 ± 0.378
1.337ProGly: 1.337 ± 0.414
0.501ProHis: 0.501 ± 0.298
3.342ProIle: 3.342 ± 0.87
2.005ProLys: 2.005 ± 0.742
1.337ProLeu: 1.337 ± 0.22
1.003ProMet: 1.003 ± 0.499
3.175ProAsn: 3.175 ± 1.079
1.337ProPro: 1.337 ± 0.463
0.835ProGln: 0.835 ± 0.311
1.671ProArg: 1.671 ± 0.277
2.172ProSer: 2.172 ± 0.672
2.339ProThr: 2.339 ± 0.345
2.506ProVal: 2.506 ± 0.722
0.0ProTrp: 0.0 ± 0.0
2.172ProTyr: 2.172 ± 0.694
0.0ProXaa: 0.0 ± 0.0
Gln
2.005GlnAla: 2.005 ± 0.583
0.501GlnCys: 0.501 ± 0.27
1.504GlnAsp: 1.504 ± 0.699
2.506GlnGlu: 2.506 ± 0.503
1.504GlnPhe: 1.504 ± 0.546
0.668GlnGly: 0.668 ± 0.301
0.334GlnHis: 0.334 ± 0.209
3.676GlnIle: 3.676 ± 1.158
3.175GlnLys: 3.175 ± 0.532
5.347GlnLeu: 5.347 ± 0.744
1.003GlnMet: 1.003 ± 0.593
2.673GlnAsn: 2.673 ± 0.542
1.17GlnPro: 1.17 ± 0.464
1.838GlnGln: 1.838 ± 0.632
2.339GlnArg: 2.339 ± 0.836
1.504GlnSer: 1.504 ± 0.261
2.84GlnThr: 2.84 ± 0.974
3.342GlnVal: 3.342 ± 0.639
0.668GlnTrp: 0.668 ± 0.302
2.005GlnTyr: 2.005 ± 0.393
0.0GlnXaa: 0.0 ± 0.0
Arg
2.339ArgAla: 2.339 ± 0.625
0.835ArgCys: 0.835 ± 0.344
3.008ArgAsp: 3.008 ± 0.54
3.008ArgGlu: 3.008 ± 0.525
2.506ArgPhe: 2.506 ± 0.741
1.838ArgGly: 1.838 ± 0.361
0.668ArgHis: 0.668 ± 0.349
3.676ArgIle: 3.676 ± 0.645
2.84ArgLys: 2.84 ± 0.74
3.843ArgLeu: 3.843 ± 0.962
1.671ArgMet: 1.671 ± 0.626
3.509ArgAsn: 3.509 ± 0.722
0.835ArgPro: 0.835 ± 0.468
2.172ArgGln: 2.172 ± 0.567
3.175ArgArg: 3.175 ± 0.798
3.676ArgSer: 3.676 ± 0.763
2.339ArgThr: 2.339 ± 0.558
2.673ArgVal: 2.673 ± 0.388
0.835ArgTrp: 0.835 ± 0.321
2.005ArgTyr: 2.005 ± 0.418
0.0ArgXaa: 0.0 ± 0.0
Ser
3.342SerAla: 3.342 ± 0.971
1.337SerCys: 1.337 ± 0.844
5.347SerAsp: 5.347 ± 1.024
5.347SerGlu: 5.347 ± 0.971
3.008SerPhe: 3.008 ± 0.665
2.673SerGly: 2.673 ± 0.673
0.835SerHis: 0.835 ± 0.531
5.347SerIle: 5.347 ± 0.881
5.347SerLys: 5.347 ± 0.647
8.187SerLeu: 8.187 ± 1.658
1.337SerMet: 1.337 ± 0.282
5.681SerAsn: 5.681 ± 1.049
1.17SerPro: 1.17 ± 0.301
3.175SerGln: 3.175 ± 0.681
4.511SerArg: 4.511 ± 0.942
6.015SerSer: 6.015 ± 1.632
5.514SerThr: 5.514 ± 1.452
4.845SerVal: 4.845 ± 0.631
0.501SerTrp: 0.501 ± 0.369
4.344SerTyr: 4.344 ± 1.039
0.0SerXaa: 0.0 ± 0.0
Thr
2.172ThrAla: 2.172 ± 0.555
1.337ThrCys: 1.337 ± 0.781
3.676ThrAsp: 3.676 ± 1.097
3.843ThrGlu: 3.843 ± 0.551
3.008ThrPhe: 3.008 ± 0.377
2.172ThrGly: 2.172 ± 0.597
0.835ThrHis: 0.835 ± 0.255
6.015ThrIle: 6.015 ± 1.064
5.013ThrLys: 5.013 ± 0.773
7.018ThrLeu: 7.018 ± 1.02
1.504ThrMet: 1.504 ± 0.43
4.177ThrAsn: 4.177 ± 0.707
1.671ThrPro: 1.671 ± 0.469
2.84ThrGln: 2.84 ± 0.837
2.339ThrArg: 2.339 ± 0.448
5.18ThrSer: 5.18 ± 1.038
5.013ThrThr: 5.013 ± 0.728
4.177ThrVal: 4.177 ± 0.8
0.501ThrTrp: 0.501 ± 0.229
2.506ThrTyr: 2.506 ± 0.708
0.0ThrXaa: 0.0 ± 0.0
Val
5.681ValAla: 5.681 ± 0.499
0.501ValCys: 0.501 ± 0.435
4.678ValAsp: 4.678 ± 0.74
2.673ValGlu: 2.673 ± 0.673
2.339ValPhe: 2.339 ± 0.54
2.172ValGly: 2.172 ± 0.342
0.668ValHis: 0.668 ± 0.303
5.681ValIle: 5.681 ± 0.916
3.509ValLys: 3.509 ± 0.985
5.347ValLeu: 5.347 ± 0.694
1.337ValMet: 1.337 ± 0.475
5.013ValAsn: 5.013 ± 0.732
2.673ValPro: 2.673 ± 0.776
2.673ValGln: 2.673 ± 0.691
3.008ValArg: 3.008 ± 0.63
5.347ValSer: 5.347 ± 0.833
4.344ValThr: 4.344 ± 0.918
3.008ValVal: 3.008 ± 0.754
0.501ValTrp: 0.501 ± 0.511
2.506ValTyr: 2.506 ± 0.636
0.0ValXaa: 0.0 ± 0.0
Trp
0.334TrpAla: 0.334 ± 0.192
0.0TrpCys: 0.0 ± 0.0
0.835TrpAsp: 0.835 ± 0.27
0.0TrpGlu: 0.0 ± 0.0
0.167TrpPhe: 0.167 ± 0.133
0.167TrpGly: 0.167 ± 0.159
0.167TrpHis: 0.167 ± 0.151
1.504TrpIle: 1.504 ± 0.429
2.172TrpLys: 2.172 ± 0.537
2.005TrpLeu: 2.005 ± 0.713
0.501TrpMet: 0.501 ± 0.352
0.167TrpAsn: 0.167 ± 0.185
0.668TrpPro: 0.668 ± 0.348
0.334TrpGln: 0.334 ± 0.259
0.501TrpArg: 0.501 ± 0.347
0.501TrpSer: 0.501 ± 0.312
0.835TrpThr: 0.835 ± 0.474
0.501TrpVal: 0.501 ± 0.364
0.167TrpTrp: 0.167 ± 0.202
0.167TrpTyr: 0.167 ± 0.139
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.673TyrAla: 2.673 ± 0.932
0.668TyrCys: 0.668 ± 0.334
3.008TyrAsp: 3.008 ± 0.898
3.676TyrGlu: 3.676 ± 0.741
2.005TyrPhe: 2.005 ± 0.587
2.005TyrGly: 2.005 ± 0.877
0.334TyrHis: 0.334 ± 0.206
3.676TyrIle: 3.676 ± 0.827
3.175TyrLys: 3.175 ± 0.888
3.175TyrLeu: 3.175 ± 1.001
1.504TyrMet: 1.504 ± 0.68
4.177TyrAsn: 4.177 ± 0.655
1.337TyrPro: 1.337 ± 0.405
2.005TyrGln: 2.005 ± 0.501
3.175TyrArg: 3.175 ± 0.727
4.511TyrSer: 4.511 ± 1.081
2.84TyrThr: 2.84 ± 0.861
3.342TyrVal: 3.342 ± 0.646
0.835TyrTrp: 0.835 ± 0.295
3.175TyrTyr: 3.175 ± 1.266
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (5986 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski