Amino acid dipepetide frequency for Rodent Torque teno virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.615AlaAla: 4.615 ± 1.918
0.0AlaCys: 0.0 ± 0.0
4.615AlaAsp: 4.615 ± 1.918
4.615AlaGlu: 4.615 ± 3.66
4.615AlaPhe: 4.615 ± 3.66
1.538AlaGly: 1.538 ± 4.939
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
4.615AlaLys: 4.615 ± 1.918
3.077AlaLeu: 3.077 ± 4.3
0.0AlaMet: 0.0 ± 0.0
1.538AlaAsn: 1.538 ± 0.639
3.077AlaPro: 3.077 ± 1.279
3.077AlaGln: 3.077 ± 4.3
1.538AlaArg: 1.538 ± 0.639
6.154AlaSer: 6.154 ± 2.558
3.077AlaThr: 3.077 ± 1.279
6.154AlaVal: 6.154 ± 3.021
1.538AlaTrp: 1.538 ± 0.639
1.538AlaTyr: 1.538 ± 0.639
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.538CysAsp: 1.538 ± 4.939
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.538CysGly: 1.538 ± 4.939
1.538CysHis: 1.538 ± 0.639
1.538CysIle: 1.538 ± 0.639
1.538CysLys: 1.538 ± 0.639
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.538CysArg: 1.538 ± 0.639
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.538AspAla: 1.538 ± 0.639
1.538AspCys: 1.538 ± 4.939
1.538AspAsp: 1.538 ± 0.639
4.615AspGlu: 4.615 ± 1.918
3.077AspPhe: 3.077 ± 1.279
4.615AspGly: 4.615 ± 3.66
0.0AspHis: 0.0 ± 0.0
3.077AspIle: 3.077 ± 1.279
1.538AspLys: 1.538 ± 0.639
1.538AspLeu: 1.538 ± 0.639
0.0AspMet: 0.0 ± 0.0
1.538AspAsn: 1.538 ± 0.639
3.077AspPro: 3.077 ± 4.3
1.538AspGln: 1.538 ± 0.639
4.615AspArg: 4.615 ± 1.918
6.154AspSer: 6.154 ± 2.558
7.692AspThr: 7.692 ± 2.382
0.0AspVal: 0.0 ± 0.0
3.077AspTrp: 3.077 ± 1.279
3.077AspTyr: 3.077 ± 1.279
0.0AspXaa: 0.0 ± 0.0
Glu
3.077GluAla: 3.077 ± 4.3
0.0GluCys: 0.0 ± 0.0
7.692GluAsp: 7.692 ± 2.382
3.077GluGlu: 3.077 ± 1.279
0.0GluPhe: 0.0 ± 0.0
9.231GluGly: 9.231 ± 7.321
1.538GluHis: 1.538 ± 4.939
3.077GluIle: 3.077 ± 1.279
3.077GluLys: 3.077 ± 1.279
3.077GluLeu: 3.077 ± 4.3
1.538GluMet: 1.538 ± 0.639
1.538GluAsn: 1.538 ± 0.639
3.077GluPro: 3.077 ± 1.279
0.0GluGln: 0.0 ± 0.0
3.077GluArg: 3.077 ± 1.279
1.538GluSer: 1.538 ± 0.639
9.231GluThr: 9.231 ± 3.836
3.077GluVal: 3.077 ± 1.279
1.538GluTrp: 1.538 ± 0.639
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.538PheCys: 1.538 ± 4.939
0.0PheAsp: 0.0 ± 0.0
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
3.077PheGly: 3.077 ± 1.279
0.0PheHis: 0.0 ± 0.0
1.538PheIle: 1.538 ± 0.639
3.077PheLys: 3.077 ± 4.3
1.538PheLeu: 1.538 ± 0.639
1.538PheMet: 1.538 ± 0.639
0.0PheAsn: 0.0 ± 0.0
1.538PhePro: 1.538 ± 0.639
3.077PheGln: 3.077 ± 1.279
3.077PheArg: 3.077 ± 4.3
0.0PheSer: 0.0 ± 0.0
3.077PheThr: 3.077 ± 1.279
1.538PheVal: 1.538 ± 4.939
4.615PheTrp: 4.615 ± 1.918
3.077PheTyr: 3.077 ± 1.279
0.0PheXaa: 0.0 ± 0.0
Gly
3.077GlyAla: 3.077 ± 1.279
0.0GlyCys: 0.0 ± 0.0
1.538GlyAsp: 1.538 ± 4.939
6.154GlyGlu: 6.154 ± 14.178
0.0GlyPhe: 0.0 ± 0.0
9.231GlyGly: 9.231 ± 7.321
1.538GlyHis: 1.538 ± 0.639
6.154GlyIle: 6.154 ± 2.558
3.077GlyLys: 3.077 ± 1.279
3.077GlyLeu: 3.077 ± 1.279
1.538GlyMet: 1.538 ± 2.518
4.615GlyAsn: 4.615 ± 1.918
6.154GlyPro: 6.154 ± 3.021
1.538GlyGln: 1.538 ± 0.639
4.615GlyArg: 4.615 ± 1.918
6.154GlySer: 6.154 ± 3.021
7.692GlyThr: 7.692 ± 2.382
4.615GlyVal: 4.615 ± 1.918
1.538GlyTrp: 1.538 ± 4.939
4.615GlyTyr: 4.615 ± 1.918
0.0GlyXaa: 0.0 ± 0.0
His
1.538HisAla: 1.538 ± 0.639
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.538HisGlu: 1.538 ± 0.639
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.538HisHis: 1.538 ± 0.639
1.538HisIle: 1.538 ± 0.639
1.538HisLys: 1.538 ± 0.639
3.077HisLeu: 3.077 ± 4.3
0.0HisMet: 0.0 ± 0.0
1.538HisAsn: 1.538 ± 0.639
3.077HisPro: 3.077 ± 1.279
0.0HisGln: 0.0 ± 0.0
4.615HisArg: 4.615 ± 3.66
0.0HisSer: 0.0 ± 0.0
4.615HisThr: 4.615 ± 3.66
1.538HisVal: 1.538 ± 0.639
1.538HisTrp: 1.538 ± 0.639
3.077HisTyr: 3.077 ± 1.279
0.0HisXaa: 0.0 ± 0.0
Ile
3.077IleAla: 3.077 ± 1.279
1.538IleCys: 1.538 ± 0.639
1.538IleAsp: 1.538 ± 0.639
0.0IleGlu: 0.0 ± 0.0
1.538IlePhe: 1.538 ± 0.639
1.538IleGly: 1.538 ± 0.639
1.538IleHis: 1.538 ± 0.639
3.077IleIle: 3.077 ± 1.279
1.538IleLys: 1.538 ± 0.639
6.154IleLeu: 6.154 ± 3.021
0.0IleMet: 0.0 ± 0.625
3.077IleAsn: 3.077 ± 1.279
1.538IlePro: 1.538 ± 0.639
3.077IleGln: 3.077 ± 1.279
4.615IleArg: 4.615 ± 1.918
1.538IleSer: 1.538 ± 0.639
3.077IleThr: 3.077 ± 1.279
1.538IleVal: 1.538 ± 0.639
1.538IleTrp: 1.538 ± 0.639
1.538IleTyr: 1.538 ± 0.639
0.0IleXaa: 0.0 ± 0.0
Lys
4.615LysAla: 4.615 ± 1.918
1.538LysCys: 1.538 ± 0.639
3.077LysAsp: 3.077 ± 1.279
1.538LysGlu: 1.538 ± 0.639
0.0LysPhe: 0.0 ± 0.0
3.077LysGly: 3.077 ± 1.279
3.077LysHis: 3.077 ± 1.279
4.615LysIle: 4.615 ± 1.918
1.538LysLys: 1.538 ± 0.639
4.615LysLeu: 4.615 ± 1.918
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
4.615LysPro: 4.615 ± 1.918
4.615LysGln: 4.615 ± 3.66
4.615LysArg: 4.615 ± 1.918
1.538LysSer: 1.538 ± 0.639
1.538LysThr: 1.538 ± 0.639
0.0LysVal: 0.0 ± 0.0
3.077LysTrp: 3.077 ± 1.279
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
3.077LeuAla: 3.077 ± 9.879
1.538LeuCys: 1.538 ± 0.639
7.692LeuAsp: 7.692 ± 2.382
1.538LeuGlu: 1.538 ± 0.639
3.077LeuPhe: 3.077 ± 9.879
4.615LeuGly: 4.615 ± 3.66
0.0LeuHis: 0.0 ± 0.0
3.077LeuIle: 3.077 ± 1.279
1.538LeuLys: 1.538 ± 0.639
9.231LeuLeu: 9.231 ± 1.742
1.538LeuMet: 1.538 ± 0.639
0.0LeuAsn: 0.0 ± 0.0
4.615LeuPro: 4.615 ± 1.918
3.077LeuGln: 3.077 ± 1.279
7.692LeuArg: 7.692 ± 3.197
1.538LeuSer: 1.538 ± 0.639
7.692LeuThr: 7.692 ± 3.197
3.077LeuVal: 3.077 ± 1.279
3.077LeuTrp: 3.077 ± 1.279
4.615LeuTyr: 4.615 ± 1.918
0.0LeuXaa: 0.0 ± 0.0
Met
4.615MetAla: 4.615 ± 1.918
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.538MetGlu: 1.538 ± 4.939
1.538MetPhe: 1.538 ± 0.639
1.538MetGly: 1.538 ± 0.639
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
1.538MetMet: 1.538 ± 0.639
1.538MetAsn: 1.538 ± 4.939
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.538MetArg: 1.538 ± 0.639
0.0MetSer: 0.0 ± 0.0
1.538MetThr: 1.538 ± 0.639
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.538MetTyr: 1.538 ± 0.639
0.0MetXaa: 0.0 ± 0.0
Asn
1.538AsnAla: 1.538 ± 0.639
0.0AsnCys: 0.0 ± 0.0
1.538AsnAsp: 1.538 ± 0.639
1.538AsnGlu: 1.538 ± 0.639
1.538AsnPhe: 1.538 ± 0.639
0.0AsnGly: 0.0 ± 0.0
3.077AsnHis: 3.077 ± 1.279
0.0AsnIle: 0.0 ± 0.0
1.538AsnLys: 1.538 ± 0.639
1.538AsnLeu: 1.538 ± 0.639
1.538AsnMet: 1.538 ± 0.639
3.077AsnAsn: 3.077 ± 1.279
6.154AsnPro: 6.154 ± 3.021
1.538AsnGln: 1.538 ± 0.639
6.154AsnArg: 6.154 ± 2.558
1.538AsnSer: 1.538 ± 0.639
3.077AsnThr: 3.077 ± 1.279
1.538AsnVal: 1.538 ± 0.639
1.538AsnTrp: 1.538 ± 0.639
1.538AsnTyr: 1.538 ± 0.639
0.0AsnXaa: 0.0 ± 0.0
Pro
3.077ProAla: 3.077 ± 1.279
0.0ProCys: 0.0 ± 0.0
4.615ProAsp: 4.615 ± 1.918
4.615ProGlu: 4.615 ± 1.918
3.077ProPhe: 3.077 ± 4.3
6.154ProGly: 6.154 ± 2.558
4.615ProHis: 4.615 ± 1.918
0.0ProIle: 0.0 ± 0.0
4.615ProLys: 4.615 ± 1.918
6.154ProLeu: 6.154 ± 2.558
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
9.231ProPro: 9.231 ± 3.836
0.0ProGln: 0.0 ± 0.0
1.538ProArg: 1.538 ± 0.639
6.154ProSer: 6.154 ± 3.021
4.615ProThr: 4.615 ± 1.918
1.538ProVal: 1.538 ± 4.939
3.077ProTrp: 3.077 ± 1.279
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
6.154GlnAla: 6.154 ± 3.021
0.0GlnCys: 0.0 ± 0.0
3.077GlnAsp: 3.077 ± 1.279
3.077GlnGlu: 3.077 ± 4.3
1.538GlnPhe: 1.538 ± 0.639
3.077GlnGly: 3.077 ± 1.279
4.615GlnHis: 4.615 ± 9.239
1.538GlnIle: 1.538 ± 0.639
0.0GlnLys: 0.0 ± 0.0
3.077GlnLeu: 3.077 ± 1.279
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
1.538GlnGln: 1.538 ± 4.939
3.077GlnArg: 3.077 ± 1.279
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
1.538GlnVal: 1.538 ± 0.639
3.077GlnTrp: 3.077 ± 1.279
3.077GlnTyr: 3.077 ± 1.279
0.0GlnXaa: 0.0 ± 0.0
Arg
6.154ArgAla: 6.154 ± 3.021
0.0ArgCys: 0.0 ± 0.0
3.077ArgAsp: 3.077 ± 1.279
1.538ArgGlu: 1.538 ± 0.639
1.538ArgPhe: 1.538 ± 0.639
0.0ArgGly: 0.0 ± 0.0
6.154ArgHis: 6.154 ± 2.558
7.692ArgIle: 7.692 ± 3.197
3.077ArgLys: 3.077 ± 1.279
6.154ArgLeu: 6.154 ± 3.021
0.0ArgMet: 0.0 ± 0.0
7.692ArgAsn: 7.692 ± 3.197
6.154ArgPro: 6.154 ± 2.558
7.692ArgGln: 7.692 ± 2.382
24.615ArgArg: 24.615 ± 10.23
1.538ArgSer: 1.538 ± 0.639
6.154ArgThr: 6.154 ± 3.021
3.077ArgVal: 3.077 ± 1.279
4.615ArgTrp: 4.615 ± 1.918
7.692ArgTyr: 7.692 ± 3.197
0.0ArgXaa: 0.0 ± 0.0
Ser
3.077SerAla: 3.077 ± 1.279
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
3.077SerGlu: 3.077 ± 1.279
1.538SerPhe: 1.538 ± 0.639
7.692SerGly: 7.692 ± 3.197
0.0SerHis: 0.0 ± 0.0
3.077SerIle: 3.077 ± 4.3
4.615SerLys: 4.615 ± 1.918
4.615SerLeu: 4.615 ± 1.918
1.538SerMet: 1.538 ± 4.939
4.615SerAsn: 4.615 ± 1.918
0.0SerPro: 0.0 ± 0.0
1.538SerGln: 1.538 ± 0.639
1.538SerArg: 1.538 ± 0.639
4.615SerSer: 4.615 ± 1.918
3.077SerThr: 3.077 ± 4.3
0.0SerVal: 0.0 ± 0.0
3.077SerTrp: 3.077 ± 1.279
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.615ThrAla: 4.615 ± 3.66
0.0ThrCys: 0.0 ± 0.0
4.615ThrAsp: 4.615 ± 1.918
10.769ThrGlu: 10.769 ± 4.476
3.077ThrPhe: 3.077 ± 1.279
12.308ThrGly: 12.308 ± 11.621
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
4.615ThrLys: 4.615 ± 1.918
7.692ThrLeu: 7.692 ± 2.382
1.538ThrMet: 1.538 ± 0.639
3.077ThrAsn: 3.077 ± 1.279
1.538ThrPro: 1.538 ± 0.639
3.077ThrGln: 3.077 ± 1.279
3.077ThrArg: 3.077 ± 1.279
3.077ThrSer: 3.077 ± 4.3
6.154ThrThr: 6.154 ± 8.6
3.077ThrVal: 3.077 ± 1.279
1.538ThrTrp: 1.538 ± 0.639
7.692ThrTyr: 7.692 ± 3.197
0.0ThrXaa: 0.0 ± 0.0
Val
1.538ValAla: 1.538 ± 0.639
1.538ValCys: 1.538 ± 0.639
3.077ValAsp: 3.077 ± 1.279
3.077ValGlu: 3.077 ± 1.279
0.0ValPhe: 0.0 ± 0.0
1.538ValGly: 1.538 ± 0.639
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
4.615ValLys: 4.615 ± 1.918
4.615ValLeu: 4.615 ± 1.918
1.538ValMet: 1.538 ± 0.639
0.0ValAsn: 0.0 ± 0.0
1.538ValPro: 1.538 ± 0.639
3.077ValGln: 3.077 ± 4.3
4.615ValArg: 4.615 ± 3.66
0.0ValSer: 0.0 ± 0.0
4.615ValThr: 4.615 ± 3.66
3.077ValVal: 3.077 ± 1.279
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.538TrpAsp: 1.538 ± 0.639
6.154TrpGlu: 6.154 ± 2.558
0.0TrpPhe: 0.0 ± 0.0
3.077TrpGly: 3.077 ± 1.279
1.538TrpHis: 1.538 ± 0.639
1.538TrpIle: 1.538 ± 0.639
1.538TrpLys: 1.538 ± 0.639
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
3.077TrpAsn: 3.077 ± 1.279
4.615TrpPro: 4.615 ± 1.918
0.0TrpGln: 0.0 ± 0.0
7.692TrpArg: 7.692 ± 2.382
3.077TrpSer: 3.077 ± 1.279
3.077TrpThr: 3.077 ± 1.279
1.538TrpVal: 1.538 ± 0.639
1.538TrpTrp: 1.538 ± 0.639
1.538TrpTyr: 1.538 ± 0.639
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
3.077TyrAsp: 3.077 ± 1.279
0.0TyrGlu: 0.0 ± 0.0
6.154TyrPhe: 6.154 ± 2.558
3.077TyrGly: 3.077 ± 1.279
0.0TyrHis: 0.0 ± 0.0
3.077TyrIle: 3.077 ± 1.279
0.0TyrLys: 0.0 ± 0.0
3.077TyrLeu: 3.077 ± 1.279
1.538TyrMet: 1.538 ± 0.639
3.077TyrAsn: 3.077 ± 1.279
3.077TyrPro: 3.077 ± 1.279
0.0TyrGln: 0.0 ± 0.0
10.769TyrArg: 10.769 ± 4.476
3.077TyrSer: 3.077 ± 1.279
1.538TyrThr: 1.538 ± 0.639
1.538TyrVal: 1.538 ± 0.639
1.538TyrTrp: 1.538 ± 0.639
3.077TyrTyr: 3.077 ± 1.279
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (651 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski