Amino acid dipepetide frequency for Leptomonas pyrrhocoris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.652AlaAla: 21.652 ± 0.144	1.445AlaCys: 1.445 ± 0.017	5.562AlaAsp: 5.562 ± 0.036	7.424AlaGlu: 7.424 ± 0.059	3.107AlaPhe: 3.107 ± 0.028	6.852AlaGly: 6.852 ± 0.05	2.577AlaHis: 2.577 ± 0.023	2.768AlaIle: 2.768 ± 0.028	3.853AlaLys: 3.853 ± 0.034	9.757AlaLeu: 9.757 ± 0.061	2.464AlaMet: 2.464 ± 0.023	2.973AlaAsn: 2.973 ± 0.024	6.805AlaPro: 6.805 ± 0.054	4.465AlaGln: 4.465 ± 0.036	6.429AlaArg: 6.429 ± 0.038	10.252AlaSer: 10.252 ± 0.07	7.946AlaThr: 7.946 ± 0.049	8.91AlaVal: 8.91 ± 0.056	0.977AlaTrp: 0.977 ± 0.015	2.202AlaTyr: 2.202 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.765CysAla: 1.765 ± 0.026	0.509CysCys: 0.509 ± 0.011	0.798CysAsp: 0.798 ± 0.013	0.782CysGlu: 0.782 ± 0.011	0.673CysPhe: 0.673 ± 0.012	1.423CysGly: 1.423 ± 0.021	0.377CysHis: 0.377 ± 0.009	0.613CysIle: 0.613 ± 0.012	0.425CysLys: 0.425 ± 0.009	1.43CysLeu: 1.43 ± 0.017	0.344CysMet: 0.344 ± 0.008	0.436CysAsn: 0.436 ± 0.009	0.819CysPro: 0.819 ± 0.014	0.42CysGln: 0.42 ± 0.01	1.08CysArg: 1.08 ± 0.014	1.26CysSer: 1.26 ± 0.019	1.07CysThr: 1.07 ± 0.015	1.561CysVal: 1.561 ± 0.022	0.198CysTrp: 0.198 ± 0.007	0.442CysTyr: 0.442 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.893AspAla: 6.893 ± 0.047	0.648AspCys: 0.648 ± 0.011	3.964AspAsp: 3.964 ± 0.037	3.813AspGlu: 3.813 ± 0.032	1.592AspPhe: 1.592 ± 0.021	4.384AspGly: 4.384 ± 0.031	0.962AspHis: 0.962 ± 0.014	1.613AspIle: 1.613 ± 0.019	1.459AspLys: 1.459 ± 0.021	3.598AspLeu: 3.598 ± 0.029	1.0AspMet: 1.0 ± 0.014	1.483AspAsn: 1.483 ± 0.016	2.42AspPro: 2.42 ± 0.033	1.125AspGln: 1.125 ± 0.016	2.752AspArg: 2.752 ± 0.028	3.387AspSer: 3.387 ± 0.026	2.809AspThr: 2.809 ± 0.021	4.537AspVal: 4.537 ± 0.031	0.494AspTrp: 0.494 ± 0.01	1.176AspTyr: 1.176 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	7.173GluAla: 7.173 ± 0.057	0.75GluCys: 0.75 ± 0.013	3.751GluAsp: 3.751 ± 0.037	6.567GluGlu: 6.567 ± 0.06	1.322GluPhe: 1.322 ± 0.016	4.011GluGly: 4.011 ± 0.029	1.384GluHis: 1.384 ± 0.016	1.456GluIle: 1.456 ± 0.019	2.951GluLys: 2.951 ± 0.03	5.483GluLeu: 5.483 ± 0.044	1.538GluMet: 1.538 ± 0.018	1.68GluAsn: 1.68 ± 0.023	2.103GluPro: 2.103 ± 0.022	2.599GluGln: 2.599 ± 0.029	4.465GluArg: 4.465 ± 0.035	3.695GluSer: 3.695 ± 0.028	3.005GluThr: 3.005 ± 0.024	4.516GluVal: 4.516 ± 0.028	0.706GluTrp: 0.706 ± 0.014	1.264GluTyr: 1.264 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.029PheAla: 3.029 ± 0.026	0.644PheCys: 0.644 ± 0.011	1.661PheAsp: 1.661 ± 0.019	1.444PheGlu: 1.444 ± 0.017	1.61PhePhe: 1.61 ± 0.023	1.974PheGly: 1.974 ± 0.023	0.912PheHis: 0.912 ± 0.013	1.136PheIle: 1.136 ± 0.016	0.839PheLys: 0.839 ± 0.014	3.142PheLeu: 3.142 ± 0.027	0.703PheMet: 0.703 ± 0.011	1.007PheAsn: 1.007 ± 0.015	1.655PhePro: 1.655 ± 0.02	1.058PheGln: 1.058 ± 0.013	1.755PheArg: 1.755 ± 0.02	2.744PheSer: 2.744 ± 0.023	1.989PheThr: 1.989 ± 0.024	2.45PheVal: 2.45 ± 0.025	0.302PheTrp: 0.302 ± 0.007	1.018PheTyr: 1.018 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	7.307GlyAla: 7.307 ± 0.047	1.088GlyCys: 1.088 ± 0.016	3.718GlyAsp: 3.718 ± 0.03	3.92GlyGlu: 3.92 ± 0.027	1.87GlyPhe: 1.87 ± 0.023	7.582GlyGly: 7.582 ± 0.082	1.435GlyHis: 1.435 ± 0.016	1.879GlyIle: 1.879 ± 0.017	2.357GlyLys: 2.357 ± 0.023	4.359GlyLeu: 4.359 ± 0.031	1.261GlyMet: 1.261 ± 0.016	2.255GlyAsn: 2.255 ± 0.023	2.607GlyPro: 2.607 ± 0.029	1.864GlyGln: 1.864 ± 0.02	4.178GlyArg: 4.178 ± 0.036	5.932GlySer: 5.932 ± 0.051	3.892GlyThr: 3.892 ± 0.031	4.937GlyVal: 4.937 ± 0.031	0.642GlyTrp: 0.642 ± 0.011	1.462GlyTyr: 1.462 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.672HisAla: 2.672 ± 0.025	0.491HisCys: 0.491 ± 0.011	1.349HisAsp: 1.349 ± 0.016	1.318HisGlu: 1.318 ± 0.019	0.863HisPhe: 0.863 ± 0.014	1.733HisGly: 1.733 ± 0.02	1.167HisHis: 1.167 ± 0.02	0.858HisIle: 0.858 ± 0.013	0.718HisLys: 0.718 ± 0.012	2.349HisLeu: 2.349 ± 0.024	0.481HisMet: 0.481 ± 0.01	0.93HisAsn: 0.93 ± 0.014	1.709HisPro: 1.709 ± 0.019	1.007HisGln: 1.007 ± 0.014	2.32HisArg: 2.32 ± 0.022	1.999HisSer: 1.999 ± 0.021	1.652HisThr: 1.652 ± 0.017	1.894HisVal: 1.894 ± 0.019	0.268HisTrp: 0.268 ± 0.007	0.716HisTyr: 0.716 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.115IleAla: 3.115 ± 0.024	0.535IleCys: 0.535 ± 0.01	1.595IleAsp: 1.595 ± 0.022	1.667IleGlu: 1.667 ± 0.02	1.096IlePhe: 1.096 ± 0.017	1.796IleGly: 1.796 ± 0.022	0.774IleHis: 0.774 ± 0.011	1.083IleIle: 1.083 ± 0.019	0.939IleLys: 0.939 ± 0.014	2.331IleLeu: 2.331 ± 0.025	0.604IleMet: 0.604 ± 0.012	0.933IleAsn: 0.933 ± 0.014	1.771IlePro: 1.771 ± 0.02	1.041IleGln: 1.041 ± 0.014	1.86IleArg: 1.86 ± 0.018	2.187IleSer: 2.187 ± 0.024	1.872IleThr: 1.872 ± 0.024	2.221IleVal: 2.221 ± 0.024	0.251IleTrp: 0.251 ± 0.007	0.743IleTyr: 0.743 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	3.691LysAla: 3.691 ± 0.035	0.422LysCys: 0.422 ± 0.01	1.899LysAsp: 1.899 ± 0.023	2.835LysGlu: 2.835 ± 0.031	0.789LysPhe: 0.789 ± 0.014	2.124LysGly: 2.124 ± 0.024	0.796LysHis: 0.796 ± 0.013	0.955LysIle: 0.955 ± 0.014	2.274LysLys: 2.274 ± 0.032	2.865LysLeu: 2.865 ± 0.03	0.893LysMet: 0.893 ± 0.012	1.096LysAsn: 1.096 ± 0.015	1.659LysPro: 1.659 ± 0.021	1.473LysGln: 1.473 ± 0.02	2.634LysArg: 2.634 ± 0.028	2.362LysSer: 2.362 ± 0.024	2.031LysThr: 2.031 ± 0.024	2.139LysVal: 2.139 ± 0.019	0.342LysTrp: 0.342 ± 0.009	0.85LysTyr: 0.85 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	7.903LeuAla: 7.903 ± 0.05	1.95LeuCys: 1.95 ± 0.023	3.965LeuAsp: 3.965 ± 0.037	4.77LeuGlu: 4.77 ± 0.047	3.265LeuPhe: 3.265 ± 0.028	4.088LeuGly: 4.088 ± 0.033	3.017LeuHis: 3.017 ± 0.028	2.417LeuIle: 2.417 ± 0.025	2.916LeuLys: 2.916 ± 0.031	10.019LeuLeu: 10.019 ± 0.067	1.919LeuMet: 1.919 ± 0.021	2.491LeuAsn: 2.491 ± 0.025	5.977LeuPro: 5.977 ± 0.036	4.744LeuGln: 4.744 ± 0.038	7.772LeuArg: 7.772 ± 0.051	7.667LeuSer: 7.667 ± 0.044	5.185LeuThr: 5.185 ± 0.037	5.448LeuVal: 5.448 ± 0.037	1.051LeuTrp: 1.051 ± 0.016	2.399LeuTyr: 2.399 ± 0.021	0.001LeuXaa: 0.001 ± 0.0
Met	2.012MetAla: 2.012 ± 0.017	0.347MetCys: 0.347 ± 0.009	1.116MetAsp: 1.116 ± 0.015	1.539MetGlu: 1.539 ± 0.02	0.6MetPhe: 0.6 ± 0.011	1.152MetGly: 1.152 ± 0.017	0.559MetHis: 0.559 ± 0.011	0.583MetIle: 0.583 ± 0.012	0.907MetLys: 0.907 ± 0.014	1.96MetLeu: 1.96 ± 0.02	0.694MetMet: 0.694 ± 0.016	0.777MetAsn: 0.777 ± 0.014	1.26MetPro: 1.26 ± 0.015	1.061MetGln: 1.061 ± 0.014	1.653MetArg: 1.653 ± 0.018	1.787MetSer: 1.787 ± 0.018	1.276MetThr: 1.276 ± 0.016	1.245MetVal: 1.245 ± 0.018	0.271MetTrp: 0.271 ± 0.007	0.539MetTyr: 0.539 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.817AsnAla: 3.817 ± 0.028	0.456AsnCys: 0.456 ± 0.01	1.678AsnAsp: 1.678 ± 0.021	1.744AsnGlu: 1.744 ± 0.017	0.94AsnPhe: 0.94 ± 0.014	2.567AsnGly: 2.567 ± 0.021	0.605AsnHis: 0.605 ± 0.011	1.042AsnIle: 1.042 ± 0.014	0.99AsnLys: 0.99 ± 0.013	2.0AsnLeu: 2.0 ± 0.021	0.623AsnMet: 0.623 ± 0.01	1.347AsnAsn: 1.347 ± 0.021	1.634AsnPro: 1.634 ± 0.019	0.747AsnGln: 0.747 ± 0.013	1.686AsnArg: 1.686 ± 0.02	2.722AsnSer: 2.722 ± 0.031	2.165AsnThr: 2.165 ± 0.02	2.264AsnVal: 2.264 ± 0.025	0.275AsnTrp: 0.275 ± 0.008	0.772AsnTyr: 0.772 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	6.798ProAla: 6.798 ± 0.05	0.762ProCys: 0.762 ± 0.014	2.121ProAsp: 2.121 ± 0.021	2.519ProGlu: 2.519 ± 0.029	1.949ProPhe: 1.949 ± 0.021	2.653ProGly: 2.653 ± 0.033	1.799ProHis: 1.799 ± 0.019	1.537ProIle: 1.537 ± 0.018	1.56ProLys: 1.56 ± 0.021	5.9ProLeu: 5.9 ± 0.043	1.07ProMet: 1.07 ± 0.012	1.619ProAsn: 1.619 ± 0.019	6.881ProPro: 6.881 ± 0.092	2.653ProGln: 2.653 ± 0.031	3.789ProArg: 3.789 ± 0.035	6.962ProSer: 6.962 ± 0.057	4.246ProThr: 4.246 ± 0.038	3.779ProVal: 3.779 ± 0.029	0.526ProTrp: 0.526 ± 0.009	1.35ProTyr: 1.35 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.299GlnAla: 3.299 ± 0.03	0.636GlnCys: 0.636 ± 0.01	1.533GlnAsp: 1.533 ± 0.02	2.435GlnGlu: 2.435 ± 0.022	0.959GlnPhe: 0.959 ± 0.013	1.765GlnGly: 1.765 ± 0.021	1.556GlnHis: 1.556 ± 0.017	0.972GlnIle: 0.972 ± 0.014	1.5GlnLys: 1.5 ± 0.021	4.749GlnLeu: 4.749 ± 0.04	0.888GlnMet: 0.888 ± 0.016	1.029GlnAsn: 1.029 ± 0.015	2.455GlnPro: 2.455 ± 0.026	4.453GlnGln: 4.453 ± 0.067	4.56GlnArg: 4.56 ± 0.032	2.645GlnSer: 2.645 ± 0.024	1.989GlnThr: 1.989 ± 0.02	2.171GlnVal: 2.171 ± 0.022	0.558GlnTrp: 0.558 ± 0.01	0.974GlnTyr: 0.974 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	6.59ArgAla: 6.59 ± 0.047	1.448ArgCys: 1.448 ± 0.02	3.401ArgAsp: 3.401 ± 0.028	4.357ArgGlu: 4.357 ± 0.035	2.043ArgPhe: 2.043 ± 0.021	4.618ArgGly: 4.618 ± 0.034	2.31ArgHis: 2.31 ± 0.025	2.054ArgIle: 2.054 ± 0.02	2.565ArgLys: 2.565 ± 0.027	6.424ArgLeu: 6.424 ± 0.038	1.434ArgMet: 1.434 ± 0.017	2.105ArgAsn: 2.105 ± 0.021	3.393ArgPro: 3.393 ± 0.026	3.48ArgGln: 3.48 ± 0.031	7.482ArgArg: 7.482 ± 0.057	5.776ArgSer: 5.776 ± 0.044	3.995ArgThr: 3.995 ± 0.032	4.715ArgVal: 4.715 ± 0.033	0.94ArgTrp: 0.94 ± 0.015	1.846ArgTyr: 1.846 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	10.591SerAla: 10.591 ± 0.063	1.28SerCys: 1.28 ± 0.019	3.674SerAsp: 3.674 ± 0.029	3.576SerGlu: 3.576 ± 0.029	2.886SerPhe: 2.886 ± 0.027	5.843SerGly: 5.843 ± 0.042	1.982SerHis: 1.982 ± 0.022	2.448SerIle: 2.448 ± 0.023	2.391SerLys: 2.391 ± 0.024	7.211SerLeu: 7.211 ± 0.046	1.646SerMet: 1.646 ± 0.017	2.768SerAsn: 2.768 ± 0.028	6.79SerPro: 6.79 ± 0.064	2.573SerGln: 2.573 ± 0.025	5.288SerArg: 5.288 ± 0.039	12.103SerSer: 12.103 ± 0.109	6.49SerThr: 6.49 ± 0.046	5.576SerVal: 5.576 ± 0.039	0.767SerTrp: 0.767 ± 0.013	1.738SerTyr: 1.738 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	8.876ThrAla: 8.876 ± 0.058	0.902ThrCys: 0.902 ± 0.014	2.657ThrAsp: 2.657 ± 0.023	3.22ThrGlu: 3.22 ± 0.029	1.808ThrPhe: 1.808 ± 0.019	3.622ThrGly: 3.622 ± 0.031	1.512ThrHis: 1.512 ± 0.016	1.799ThrIle: 1.799 ± 0.018	1.919ThrLys: 1.919 ± 0.019	5.196ThrLeu: 5.196 ± 0.033	1.227ThrMet: 1.227 ± 0.015	1.845ThrAsn: 1.845 ± 0.022	4.712ThrPro: 4.712 ± 0.04	2.261ThrGln: 2.261 ± 0.021	3.709ThrArg: 3.709 ± 0.027	6.154ThrSer: 6.154 ± 0.045	5.664ThrThr: 5.664 ± 0.054	4.494ThrVal: 4.494 ± 0.037	0.566ThrTrp: 0.566 ± 0.01	1.336ThrTyr: 1.336 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	7.963ValAla: 7.963 ± 0.046	1.356ValCys: 1.356 ± 0.019	3.862ValAsp: 3.862 ± 0.027	4.586ValGlu: 4.586 ± 0.032	2.47ValPhe: 2.47 ± 0.024	4.07ValGly: 4.07 ± 0.028	1.874ValHis: 1.874 ± 0.019	2.006ValIle: 2.006 ± 0.023	2.383ValLys: 2.383 ± 0.024	7.046ValLeu: 7.046 ± 0.045	1.633ValMet: 1.633 ± 0.017	2.072ValAsn: 2.072 ± 0.02	4.278ValPro: 4.278 ± 0.034	2.868ValGln: 2.868 ± 0.026	4.919ValArg: 4.919 ± 0.036	5.554ValSer: 5.554 ± 0.036	4.102ValThr: 4.102 ± 0.035	6.053ValVal: 6.053 ± 0.038	0.759ValTrp: 0.759 ± 0.012	1.787ValTyr: 1.787 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.86TrpAla: 0.86 ± 0.014	0.283TrpCys: 0.283 ± 0.008	0.489TrpAsp: 0.489 ± 0.008	0.574TrpGlu: 0.574 ± 0.012	0.3TrpPhe: 0.3 ± 0.008	0.596TrpGly: 0.596 ± 0.011	0.248TrpHis: 0.248 ± 0.007	0.331TrpIle: 0.331 ± 0.008	0.478TrpLys: 0.478 ± 0.01	0.953TrpLeu: 0.953 ± 0.015	0.351TrpMet: 0.351 ± 0.008	0.376TrpAsn: 0.376 ± 0.009	0.403TrpPro: 0.403 ± 0.009	0.432TrpGln: 0.432 ± 0.01	0.984TrpArg: 0.984 ± 0.015	0.878TrpSer: 0.878 ± 0.014	0.627TrpThr: 0.627 ± 0.011	0.693TrpVal: 0.693 ± 0.012	0.242TrpTrp: 0.242 ± 0.008	0.314TrpTyr: 0.314 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.415TyrAla: 2.415 ± 0.024	0.475TyrCys: 0.475 ± 0.011	1.316TyrAsp: 1.316 ± 0.016	1.331TyrGlu: 1.331 ± 0.017	0.929TyrPhe: 0.929 ± 0.013	1.689TyrGly: 1.689 ± 0.02	0.649TyrHis: 0.649 ± 0.01	0.86TyrIle: 0.86 ± 0.015	0.707TyrLys: 0.707 ± 0.012	2.19TyrLeu: 2.19 ± 0.023	0.562TyrMet: 0.562 ± 0.011	0.854TyrAsn: 0.854 ± 0.012	1.141TyrPro: 1.141 ± 0.016	0.803TyrGln: 0.803 ± 0.013	1.658TyrArg: 1.658 ± 0.017	1.556TyrSer: 1.556 ± 0.019	1.474TyrThr: 1.474 ± 0.019	2.04TyrVal: 2.04 ± 0.023	0.278TyrTrp: 0.278 ± 0.008	0.857TyrTyr: 0.857 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.074XaaXaa: 0.074 ± 0.035

Statistics based on 9272 proteins (5711352 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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