Amino acid dipepetide frequency for Changjiang tombus-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.384AlaAla: 8.384 ± 3.095
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
2.287AlaGlu: 2.287 ± 1.144
2.287AlaPhe: 2.287 ± 0.886
3.049AlaGly: 3.049 ± 1.5
2.287AlaHis: 2.287 ± 1.492
0.762AlaIle: 0.762 ± 0.62
6.86AlaLys: 6.86 ± 1.665
12.195AlaLeu: 12.195 ± 1.888
3.811AlaMet: 3.811 ± 1.181
0.762AlaAsn: 0.762 ± 0.484
7.622AlaPro: 7.622 ± 2.724
3.811AlaGln: 3.811 ± 1.377
6.86AlaArg: 6.86 ± 1.684
7.622AlaSer: 7.622 ± 2.51
3.811AlaThr: 3.811 ± 1.591
12.195AlaVal: 12.195 ± 2.166
0.0AlaTrp: 0.0 ± 0.0
1.524AlaTyr: 1.524 ± 0.968
0.0AlaXaa: 0.0 ± 0.0
Cys
0.762CysAla: 0.762 ± 0.484
0.0CysCys: 0.0 ± 0.0
1.524CysAsp: 1.524 ± 0.622
0.762CysGlu: 0.762 ± 0.62
0.0CysPhe: 0.0 ± 0.0
0.762CysGly: 0.762 ± 0.62
0.762CysHis: 0.762 ± 0.77
0.762CysIle: 0.762 ± 0.484
0.0CysLys: 0.0 ± 0.0
1.524CysLeu: 1.524 ± 0.968
0.0CysMet: 0.0 ± 0.0
1.524CysAsn: 1.524 ± 0.682
1.524CysPro: 1.524 ± 1.24
0.762CysGln: 0.762 ± 0.484
3.049CysArg: 3.049 ± 1.04
0.0CysSer: 0.0 ± 0.0
0.762CysThr: 0.762 ± 0.77
0.762CysVal: 0.762 ± 0.484
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.86AspAla: 6.86 ± 1.883
2.287AspCys: 2.287 ± 0.898
0.762AspAsp: 0.762 ± 0.484
0.762AspGlu: 0.762 ± 0.813
0.762AspPhe: 0.762 ± 0.484
3.811AspGly: 3.811 ± 1.017
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
0.0AspLys: 0.0 ± 0.0
3.811AspLeu: 3.811 ± 1.734
0.762AspMet: 0.762 ± 0.484
3.811AspAsn: 3.811 ± 1.017
2.287AspPro: 2.287 ± 1.453
0.762AspGln: 0.762 ± 0.484
5.335AspArg: 5.335 ± 2.056
3.049AspSer: 3.049 ± 1.005
6.86AspThr: 6.86 ± 0.738
2.287AspVal: 2.287 ± 0.594
0.762AspTrp: 0.762 ± 0.62
0.762AspTyr: 0.762 ± 0.62
0.0AspXaa: 0.0 ± 0.0
Glu
3.811GluAla: 3.811 ± 1.502
0.762GluCys: 0.762 ± 0.62
1.524GluAsp: 1.524 ± 1.24
3.811GluGlu: 3.811 ± 0.956
1.524GluPhe: 1.524 ± 0.968
4.573GluGly: 4.573 ± 0.48
1.524GluHis: 1.524 ± 0.622
1.524GluIle: 1.524 ± 0.622
0.762GluLys: 0.762 ± 0.484
7.622GluLeu: 7.622 ± 2.535
2.287GluMet: 2.287 ± 0.752
0.762GluAsn: 0.762 ± 0.77
1.524GluPro: 1.524 ± 0.682
3.049GluGln: 3.049 ± 1.271
5.335GluArg: 5.335 ± 0.856
3.049GluSer: 3.049 ± 1.04
2.287GluThr: 2.287 ± 0.886
4.573GluVal: 4.573 ± 2.072
1.524GluTrp: 1.524 ± 0.622
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.524PheAla: 1.524 ± 0.968
0.762PheCys: 0.762 ± 0.484
2.287PheAsp: 2.287 ± 1.453
0.762PheGlu: 0.762 ± 0.484
0.0PhePhe: 0.0 ± 0.0
2.287PheGly: 2.287 ± 0.927
1.524PheHis: 1.524 ± 0.622
1.524PheIle: 1.524 ± 0.699
0.0PheLys: 0.0 ± 0.0
2.287PheLeu: 2.287 ± 0.927
0.0PheMet: 0.0 ± 0.0
3.811PheAsn: 3.811 ± 2.421
0.0PhePro: 0.0 ± 0.0
0.762PheGln: 0.762 ± 0.77
2.287PheArg: 2.287 ± 0.886
3.049PheSer: 3.049 ± 1.398
2.287PheThr: 2.287 ± 1.437
1.524PheVal: 1.524 ± 0.699
0.0PheTrp: 0.0 ± 0.0
2.287PheTyr: 2.287 ± 0.886
0.0PheXaa: 0.0 ± 0.0
Gly
3.049GlyAla: 3.049 ± 1.326
1.524GlyCys: 1.524 ± 0.682
4.573GlyAsp: 4.573 ± 1.445
6.098GlyGlu: 6.098 ± 2.168
2.287GlyPhe: 2.287 ± 0.927
7.622GlyGly: 7.622 ± 3.91
0.762GlyHis: 0.762 ± 0.77
3.049GlyIle: 3.049 ± 0.794
2.287GlyLys: 2.287 ± 0.898
6.86GlyLeu: 6.86 ± 1.283
1.524GlyMet: 1.524 ± 0.968
2.287GlyAsn: 2.287 ± 0.594
1.524GlyPro: 1.524 ± 0.897
0.762GlyGln: 0.762 ± 0.484
3.811GlyArg: 3.811 ± 1.377
5.335GlySer: 5.335 ± 0.789
4.573GlyThr: 4.573 ± 0.48
6.098GlyVal: 6.098 ± 1.364
1.524GlyTrp: 1.524 ± 0.622
1.524GlyTyr: 1.524 ± 0.682
0.0GlyXaa: 0.0 ± 0.0
His
3.049HisAla: 3.049 ± 1.227
0.0HisCys: 0.0 ± 0.0
1.524HisAsp: 1.524 ± 1.11
2.287HisGlu: 2.287 ± 0.835
0.0HisPhe: 0.0 ± 0.0
1.524HisGly: 1.524 ± 0.699
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.524HisLys: 1.524 ± 1.54
2.287HisLeu: 2.287 ± 0.927
1.524HisMet: 1.524 ± 0.582
1.524HisAsn: 1.524 ± 0.699
1.524HisPro: 1.524 ± 0.622
0.0HisGln: 0.0 ± 0.0
3.049HisArg: 3.049 ± 2.22
3.049HisSer: 3.049 ± 1.446
2.287HisThr: 2.287 ± 0.594
1.524HisVal: 1.524 ± 0.699
0.762HisTrp: 0.762 ± 0.62
0.762HisTyr: 0.762 ± 0.62
0.0HisXaa: 0.0 ± 0.0
Ile
1.524IleAla: 1.524 ± 0.897
0.0IleCys: 0.0 ± 0.0
1.524IleAsp: 1.524 ± 0.682
3.049IleGlu: 3.049 ± 1.5
0.762IlePhe: 0.762 ± 0.484
0.762IleGly: 0.762 ± 0.484
1.524IleHis: 1.524 ± 1.54
0.0IleIle: 0.0 ± 0.0
2.287IleLys: 2.287 ± 1.453
3.049IleLeu: 3.049 ± 1.795
0.0IleMet: 0.0 ± 0.0
2.287IleAsn: 2.287 ± 1.453
2.287IlePro: 2.287 ± 0.633
1.524IleGln: 1.524 ± 0.622
2.287IleArg: 2.287 ± 0.927
3.049IleSer: 3.049 ± 1.937
1.524IleThr: 1.524 ± 0.699
2.287IleVal: 2.287 ± 0.927
0.0IleTrp: 0.0 ± 0.0
0.762IleTyr: 0.762 ± 0.484
0.0IleXaa: 0.0 ± 0.0
Lys
1.524LysAla: 1.524 ± 0.968
0.0LysCys: 0.0 ± 0.0
3.811LysAsp: 3.811 ± 1.02
1.524LysGlu: 1.524 ± 0.699
2.287LysPhe: 2.287 ± 0.886
3.049LysGly: 3.049 ± 1.341
1.524LysHis: 1.524 ± 0.682
1.524LysIle: 1.524 ± 0.682
0.762LysLys: 0.762 ± 0.484
2.287LysLeu: 2.287 ± 0.886
0.0LysMet: 0.0 ± 0.619
1.524LysAsn: 1.524 ± 0.968
4.573LysPro: 4.573 ± 1.445
0.762LysGln: 0.762 ± 0.77
1.524LysArg: 1.524 ± 0.968
0.762LysSer: 0.762 ± 0.484
0.762LysThr: 0.762 ± 0.813
2.287LysVal: 2.287 ± 0.898
3.049LysTrp: 3.049 ± 1.271
2.287LysTyr: 2.287 ± 1.453
0.0LysXaa: 0.0 ± 0.0
Leu
3.811LeuAla: 3.811 ± 0.956
2.287LeuCys: 2.287 ± 1.144
3.049LeuAsp: 3.049 ± 0.586
5.335LeuGlu: 5.335 ± 1.863
3.049LeuPhe: 3.049 ± 0.682
6.86LeuGly: 6.86 ± 1.641
2.287LeuHis: 2.287 ± 1.787
2.287LeuIle: 2.287 ± 0.633
3.049LeuLys: 3.049 ± 1.341
11.433LeuLeu: 11.433 ± 3.106
1.524LeuMet: 1.524 ± 0.968
3.049LeuAsn: 3.049 ± 1.398
6.86LeuPro: 6.86 ± 3.4
4.573LeuGln: 4.573 ± 0.976
6.098LeuArg: 6.098 ± 2.057
10.671LeuSer: 10.671 ± 2.606
3.811LeuThr: 3.811 ± 1.591
4.573LeuVal: 4.573 ± 2.18
2.287LeuTrp: 2.287 ± 1.437
2.287LeuTyr: 2.287 ± 0.886
0.0LeuXaa: 0.0 ± 0.0
Met
1.524MetAla: 1.524 ± 0.844
0.0MetCys: 0.0 ± 0.0
2.287MetAsp: 2.287 ± 1.453
1.524MetGlu: 1.524 ± 0.622
0.0MetPhe: 0.0 ± 0.0
1.524MetGly: 1.524 ± 0.622
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.762MetLys: 0.762 ± 0.484
0.0MetLeu: 0.0 ± 0.0
0.762MetMet: 0.762 ± 0.484
0.762MetAsn: 0.762 ± 0.484
0.762MetPro: 0.762 ± 0.484
2.287MetGln: 2.287 ± 1.437
0.762MetArg: 0.762 ± 0.484
3.811MetSer: 3.811 ± 1.521
1.524MetThr: 1.524 ± 0.622
2.287MetVal: 2.287 ± 0.886
0.0MetTrp: 0.0 ± 0.0
0.762MetTyr: 0.762 ± 0.484
0.0MetXaa: 0.0 ± 0.0
Asn
6.86AsnAla: 6.86 ± 0.875
0.762AsnCys: 0.762 ± 0.484
0.762AsnAsp: 0.762 ± 0.813
2.287AsnGlu: 2.287 ± 0.898
0.762AsnPhe: 0.762 ± 0.484
0.762AsnGly: 0.762 ± 0.484
0.762AsnHis: 0.762 ± 0.484
0.762AsnIle: 0.762 ± 0.77
1.524AsnLys: 1.524 ± 0.968
3.049AsnLeu: 3.049 ± 1.398
0.0AsnMet: 0.0 ± 0.0
2.287AsnAsn: 2.287 ± 1.453
1.524AsnPro: 1.524 ± 0.682
0.762AsnGln: 0.762 ± 0.484
3.049AsnArg: 3.049 ± 1.5
2.287AsnSer: 2.287 ± 1.453
3.811AsnThr: 3.811 ± 0.215
2.287AsnVal: 2.287 ± 0.835
0.762AsnTrp: 0.762 ± 0.484
0.762AsnTyr: 0.762 ± 0.813
0.0AsnXaa: 0.0 ± 0.0
Pro
9.909ProAla: 9.909 ± 3.319
0.762ProCys: 0.762 ± 0.62
4.573ProAsp: 4.573 ± 0.902
0.0ProGlu: 0.0 ± 0.0
1.524ProPhe: 1.524 ± 0.699
3.811ProGly: 3.811 ± 1.782
3.049ProHis: 3.049 ± 0.794
0.0ProIle: 0.0 ± 0.0
0.762ProLys: 0.762 ± 0.813
6.86ProLeu: 6.86 ± 2.171
0.762ProMet: 0.762 ± 0.484
0.762ProAsn: 0.762 ± 0.813
9.146ProPro: 9.146 ± 2.374
3.049ProGln: 3.049 ± 1.805
9.909ProArg: 9.909 ± 3.201
5.335ProSer: 5.335 ± 2.689
8.384ProThr: 8.384 ± 2.043
9.909ProVal: 9.909 ± 0.598
1.524ProTrp: 1.524 ± 0.968
0.762ProTyr: 0.762 ± 0.813
0.0ProXaa: 0.0 ± 0.0
Gln
0.762GlnAla: 0.762 ± 0.62
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.811GlnGlu: 3.811 ± 1.476
0.762GlnPhe: 0.762 ± 0.813
3.049GlnGly: 3.049 ± 2.22
2.287GlnHis: 2.287 ± 0.898
1.524GlnIle: 1.524 ± 0.622
0.762GlnLys: 0.762 ± 0.484
3.811GlnLeu: 3.811 ± 1.119
0.762GlnMet: 0.762 ± 0.484
0.0GlnAsn: 0.0 ± 0.0
6.098GlnPro: 6.098 ± 3.277
1.524GlnGln: 1.524 ± 1.11
4.573GlnArg: 4.573 ± 2.744
2.287GlnSer: 2.287 ± 0.835
0.762GlnThr: 0.762 ± 0.484
2.287GlnVal: 2.287 ± 0.594
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.335ArgAla: 5.335 ± 2.507
2.287ArgCys: 2.287 ± 1.144
5.335ArgAsp: 5.335 ± 1.455
6.098ArgGlu: 6.098 ± 3.463
2.287ArgPhe: 2.287 ± 1.453
7.622ArgGly: 7.622 ± 4.795
2.287ArgHis: 2.287 ± 1.492
5.335ArgIle: 5.335 ± 2.195
0.762ArgLys: 0.762 ± 0.813
3.049ArgLeu: 3.049 ± 0.682
3.049ArgMet: 3.049 ± 1.341
2.287ArgAsn: 2.287 ± 1.728
9.909ArgPro: 9.909 ± 2.087
4.573ArgGln: 4.573 ± 3.726
5.335ArgArg: 5.335 ± 2.206
3.811ArgSer: 3.811 ± 1.728
5.335ArgThr: 5.335 ± 1.302
9.909ArgVal: 9.909 ± 1.762
1.524ArgTrp: 1.524 ± 0.844
2.287ArgTyr: 2.287 ± 0.886
0.0ArgXaa: 0.0 ± 0.0
Ser
6.86SerAla: 6.86 ± 1.521
0.0SerCys: 0.0 ± 0.0
3.049SerAsp: 3.049 ± 2.369
3.811SerGlu: 3.811 ± 1.782
3.049SerPhe: 3.049 ± 1.245
6.098SerGly: 6.098 ± 1.786
1.524SerHis: 1.524 ± 0.897
5.335SerIle: 5.335 ± 1.409
3.811SerLys: 3.811 ± 1.702
3.811SerLeu: 3.811 ± 2.264
1.524SerMet: 1.524 ± 0.968
2.287SerAsn: 2.287 ± 1.596
7.622SerPro: 7.622 ± 0.949
3.049SerGln: 3.049 ± 2.118
7.622SerArg: 7.622 ± 2.909
3.049SerSer: 3.049 ± 0.586
3.049SerThr: 3.049 ± 1.005
4.573SerVal: 4.573 ± 1.395
0.762SerTrp: 0.762 ± 0.62
2.287SerTyr: 2.287 ± 0.886
0.0SerXaa: 0.0 ± 0.0
Thr
8.384ThrAla: 8.384 ± 1.321
0.762ThrCys: 0.762 ± 0.62
5.335ThrAsp: 5.335 ± 1.482
0.762ThrGlu: 0.762 ± 0.484
1.524ThrPhe: 1.524 ± 0.699
4.573ThrGly: 4.573 ± 0.466
2.287ThrHis: 2.287 ± 0.633
1.524ThrIle: 1.524 ± 0.682
3.049ThrLys: 3.049 ± 1.271
3.811ThrLeu: 3.811 ± 1.591
2.287ThrMet: 2.287 ± 1.324
3.811ThrAsn: 3.811 ± 1.289
9.146ThrPro: 9.146 ± 2.708
0.762ThrGln: 0.762 ± 0.484
6.86ThrArg: 6.86 ± 0.875
6.098ThrSer: 6.098 ± 1.268
2.287ThrThr: 2.287 ± 0.898
2.287ThrVal: 2.287 ± 0.886
2.287ThrTrp: 2.287 ± 1.144
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
8.384ValAla: 8.384 ± 2.891
3.049ValCys: 3.049 ± 0.794
1.524ValAsp: 1.524 ± 0.622
6.098ValGlu: 6.098 ± 1.402
3.811ValPhe: 3.811 ± 1.017
4.573ValGly: 4.573 ± 1.111
3.811ValHis: 3.811 ± 0.956
3.049ValIle: 3.049 ± 1.937
4.573ValLys: 4.573 ± 1.332
5.335ValLeu: 5.335 ± 0.947
0.0ValMet: 0.0 ± 0.0
2.287ValAsn: 2.287 ± 1.144
5.335ValPro: 5.335 ± 2.314
0.762ValGln: 0.762 ± 0.77
8.384ValArg: 8.384 ± 2.746
4.573ValSer: 4.573 ± 1.266
6.098ValThr: 6.098 ± 2.119
4.573ValVal: 4.573 ± 0.976
0.0ValTrp: 0.0 ± 0.0
2.287ValTyr: 2.287 ± 1.453
0.0ValXaa: 0.0 ± 0.0
Trp
3.049TrpAla: 3.049 ± 1.271
0.0TrpCys: 0.0 ± 0.0
1.524TrpAsp: 1.524 ± 0.682
0.762TrpGlu: 0.762 ± 0.484
0.762TrpPhe: 0.762 ± 0.62
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.762TrpIle: 0.762 ± 0.62
0.762TrpLys: 0.762 ± 0.484
2.287TrpLeu: 2.287 ± 1.144
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.762TrpArg: 0.762 ± 0.484
1.524TrpSer: 1.524 ± 0.897
0.762TrpThr: 0.762 ± 0.484
2.287TrpVal: 2.287 ± 1.311
0.762TrpTrp: 0.762 ± 0.484
1.524TrpTyr: 1.524 ± 0.622
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.762TyrAla: 0.762 ± 0.813
0.0TyrCys: 0.0 ± 0.0
0.762TyrAsp: 0.762 ± 0.484
0.0TyrGlu: 0.0 ± 0.0
1.524TyrPhe: 1.524 ± 0.968
0.762TyrGly: 0.762 ± 0.62
0.0TyrHis: 0.0 ± 0.0
0.762TyrIle: 0.762 ± 0.484
2.287TyrLys: 2.287 ± 1.453
3.811TyrLeu: 3.811 ± 2.097
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.524TyrPro: 1.524 ± 0.699
1.524TyrGln: 1.524 ± 0.682
1.524TyrArg: 1.524 ± 0.968
0.762TyrSer: 0.762 ± 0.813
6.86TyrThr: 6.86 ± 3.679
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1313 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski