Amino acid dipepetide frequency for Conchiformibius steedae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.929AlaAla: 16.929 ± 0.385
1.302AlaCys: 1.302 ± 0.052
7.255AlaAsp: 7.255 ± 0.132
7.812AlaGlu: 7.812 ± 0.174
3.776AlaPhe: 3.776 ± 0.077
8.021AlaGly: 8.021 ± 0.132
2.487AlaHis: 2.487 ± 0.069
3.902AlaIle: 3.902 ± 0.088
5.218AlaLys: 5.218 ± 0.12
11.676AlaLeu: 11.676 ± 0.191
2.443AlaMet: 2.443 ± 0.068
3.535AlaAsn: 3.535 ± 0.073
4.446AlaPro: 4.446 ± 0.12
6.66AlaGln: 6.66 ± 0.168
5.734AlaArg: 5.734 ± 0.12
4.245AlaSer: 4.245 ± 0.086
4.117AlaThr: 4.117 ± 0.094
9.053AlaVal: 9.053 ± 0.134
1.602AlaTrp: 1.602 ± 0.064
2.909AlaTyr: 2.909 ± 0.063
0.0AlaXaa: 0.0 ± 0.0
Cys
1.26CysAla: 1.26 ± 0.055
0.165CysCys: 0.165 ± 0.016
0.537CysAsp: 0.537 ± 0.029
0.545CysGlu: 0.545 ± 0.03
0.364CysPhe: 0.364 ± 0.025
1.073CysGly: 1.073 ± 0.044
0.323CysHis: 0.323 ± 0.022
0.494CysIle: 0.494 ± 0.029
0.297CysLys: 0.297 ± 0.019
1.043CysLeu: 1.043 ± 0.045
0.196CysMet: 0.196 ± 0.016
0.322CysAsn: 0.322 ± 0.02
0.548CysPro: 0.548 ± 0.031
0.442CysGln: 0.442 ± 0.03
0.683CysArg: 0.683 ± 0.037
0.584CysSer: 0.584 ± 0.032
0.519CysThr: 0.519 ± 0.027
0.674CysVal: 0.674 ± 0.033
0.142CysTrp: 0.142 ± 0.014
0.307CysTyr: 0.307 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
5.608AspAla: 5.608 ± 0.104
0.56AspCys: 0.56 ± 0.03
2.81AspAsp: 2.81 ± 0.071
3.463AspGlu: 3.463 ± 0.081
2.613AspPhe: 2.613 ± 0.064
4.217AspGly: 4.217 ± 0.12
0.935AspHis: 0.935 ± 0.036
3.271AspIle: 3.271 ± 0.063
3.048AspLys: 3.048 ± 0.076
5.313AspLeu: 5.313 ± 0.103
1.246AspMet: 1.246 ± 0.04
2.429AspAsn: 2.429 ± 0.069
1.81AspPro: 1.81 ± 0.052
1.138AspGln: 1.138 ± 0.041
2.085AspArg: 2.085 ± 0.049
2.925AspSer: 2.925 ± 0.081
3.087AspThr: 3.087 ± 0.086
3.662AspVal: 3.662 ± 0.078
1.066AspTrp: 1.066 ± 0.042
2.037AspTyr: 2.037 ± 0.056
0.0AspXaa: 0.0 ± 0.0
Glu
6.194GluAla: 6.194 ± 0.144
0.479GluCys: 0.479 ± 0.03
2.211GluAsp: 2.211 ± 0.06
2.858GluGlu: 2.858 ± 0.099
1.901GluPhe: 1.901 ± 0.049
2.954GluGly: 2.954 ± 0.086
1.778GluHis: 1.778 ± 0.055
3.524GluIle: 3.524 ± 0.087
3.338GluLys: 3.338 ± 0.088
5.435GluLeu: 5.435 ± 0.116
1.546GluMet: 1.546 ± 0.049
2.938GluAsn: 2.938 ± 0.064
1.804GluPro: 1.804 ± 0.055
3.94GluGln: 3.94 ± 0.092
3.782GluArg: 3.782 ± 0.085
2.887GluSer: 2.887 ± 0.07
3.446GluThr: 3.446 ± 0.086
3.195GluVal: 3.195 ± 0.071
0.821GluTrp: 0.821 ± 0.039
1.704GluTyr: 1.704 ± 0.054
0.0GluXaa: 0.0 ± 0.0
Phe
4.63PheAla: 4.63 ± 0.103
0.513PheCys: 0.513 ± 0.03
2.648PheAsp: 2.648 ± 0.064
2.043PheGlu: 2.043 ± 0.055
1.675PhePhe: 1.675 ± 0.061
3.295PheGly: 3.295 ± 0.089
0.845PheHis: 0.845 ± 0.035
1.978PheIle: 1.978 ± 0.055
1.544PheLys: 1.544 ± 0.049
3.285PheLeu: 3.285 ± 0.09
0.747PheMet: 0.747 ± 0.033
1.57PheAsn: 1.57 ± 0.056
1.495PhePro: 1.495 ± 0.049
1.357PheGln: 1.357 ± 0.044
1.705PheArg: 1.705 ± 0.044
2.494PheSer: 2.494 ± 0.062
1.966PheThr: 1.966 ± 0.057
2.781PheVal: 2.781 ± 0.069
0.573PheTrp: 0.573 ± 0.03
1.276PheTyr: 1.276 ± 0.042
0.0PheXaa: 0.0 ± 0.0
Gly
6.711GlyAla: 6.711 ± 0.128
0.811GlyCys: 0.811 ± 0.04
3.511GlyAsp: 3.511 ± 0.082
4.482GlyGlu: 4.482 ± 0.081
3.032GlyPhe: 3.032 ± 0.076
5.769GlyGly: 5.769 ± 0.135
1.42GlyHis: 1.42 ± 0.044
4.318GlyIle: 4.318 ± 0.09
4.999GlyLys: 4.999 ± 0.099
6.964GlyLeu: 6.964 ± 0.12
2.104GlyMet: 2.104 ± 0.065
3.044GlyAsn: 3.044 ± 0.099
0.937GlyPro: 0.937 ± 0.039
2.864GlyGln: 2.864 ± 0.076
3.702GlyArg: 3.702 ± 0.078
4.278GlySer: 4.278 ± 0.133
3.811GlyThr: 3.811 ± 0.089
5.37GlyVal: 5.37 ± 0.104
1.07GlyTrp: 1.07 ± 0.042
2.235GlyTyr: 2.235 ± 0.054
0.0GlyXaa: 0.0 ± 0.0
His
2.723HisAla: 2.723 ± 0.082
0.316HisCys: 0.316 ± 0.023
1.238HisAsp: 1.238 ± 0.042
1.166HisGlu: 1.166 ± 0.046
1.006HisPhe: 1.006 ± 0.038
2.061HisGly: 2.061 ± 0.056
0.898HisHis: 0.898 ± 0.036
1.718HisIle: 1.718 ± 0.054
0.945HisLys: 0.945 ± 0.04
2.39HisLeu: 2.39 ± 0.062
0.442HisMet: 0.442 ± 0.025
1.053HisAsn: 1.053 ± 0.038
1.457HisPro: 1.457 ± 0.051
1.25HisGln: 1.25 ± 0.044
1.379HisArg: 1.379 ± 0.05
1.55HisSer: 1.55 ± 0.048
1.723HisThr: 1.723 ± 0.05
1.159HisVal: 1.159 ± 0.041
0.328HisTrp: 0.328 ± 0.022
0.953HisTyr: 0.953 ± 0.034
0.0HisXaa: 0.0 ± 0.0
Ile
5.966IleAla: 5.966 ± 0.107
0.534IleCys: 0.534 ± 0.03
3.141IleAsp: 3.141 ± 0.073
3.068IleGlu: 3.068 ± 0.085
1.682IlePhe: 1.682 ± 0.048
4.408IleGly: 4.408 ± 0.107
1.296IleHis: 1.296 ± 0.044
2.815IleIle: 2.815 ± 0.076
2.348IleLys: 2.348 ± 0.068
4.558IleLeu: 4.558 ± 0.094
1.089IleMet: 1.089 ± 0.042
2.336IleAsn: 2.336 ± 0.071
2.243IlePro: 2.243 ± 0.064
1.991IleGln: 1.991 ± 0.055
3.241IleArg: 3.241 ± 0.075
3.135IleSer: 3.135 ± 0.083
2.784IleThr: 2.784 ± 0.066
3.263IleVal: 3.263 ± 0.079
0.553IleTrp: 0.553 ± 0.03
1.376IleTyr: 1.376 ± 0.047
0.0IleXaa: 0.0 ± 0.0
Lys
4.343LysAla: 4.343 ± 0.089
0.225LysCys: 0.225 ± 0.019
2.358LysAsp: 2.358 ± 0.064
2.396LysGlu: 2.396 ± 0.07
1.324LysPhe: 1.324 ± 0.047
3.013LysGly: 3.013 ± 0.082
1.263LysHis: 1.263 ± 0.045
3.028LysIle: 3.028 ± 0.089
2.728LysLys: 2.728 ± 0.087
4.736LysLeu: 4.736 ± 0.091
1.325LysMet: 1.325 ± 0.05
2.356LysAsn: 2.356 ± 0.071
2.287LysPro: 2.287 ± 0.062
2.892LysGln: 2.892 ± 0.079
2.826LysArg: 2.826 ± 0.074
2.496LysSer: 2.496 ± 0.062
3.128LysThr: 3.128 ± 0.073
2.754LysVal: 2.754 ± 0.073
0.535LysTrp: 0.535 ± 0.028
1.249LysTyr: 1.249 ± 0.052
0.0LysXaa: 0.0 ± 0.0
Leu
11.991LeuAla: 11.991 ± 0.195
1.241LeuCys: 1.241 ± 0.048
5.332LeuAsp: 5.332 ± 0.119
4.626LeuGlu: 4.626 ± 0.1
3.839LeuPhe: 3.839 ± 0.094
6.598LeuGly: 6.598 ± 0.123
2.829LeuHis: 2.829 ± 0.073
4.855LeuIle: 4.855 ± 0.096
4.822LeuLys: 4.822 ± 0.091
11.234LeuLeu: 11.234 ± 0.218
2.628LeuMet: 2.628 ± 0.077
4.638LeuAsn: 4.638 ± 0.104
6.45LeuPro: 6.45 ± 0.133
4.611LeuGln: 4.611 ± 0.097
5.622LeuArg: 5.622 ± 0.096
6.565LeuSer: 6.565 ± 0.109
4.949LeuThr: 4.949 ± 0.093
5.582LeuVal: 5.582 ± 0.116
1.299LeuTrp: 1.299 ± 0.057
2.761LeuTyr: 2.761 ± 0.063
0.0LeuXaa: 0.0 ± 0.0
Met
2.454MetAla: 2.454 ± 0.066
0.225MetCys: 0.225 ± 0.017
1.095MetAsp: 1.095 ± 0.04
1.037MetGlu: 1.037 ± 0.044
0.834MetPhe: 0.834 ± 0.042
1.687MetGly: 1.687 ± 0.066
0.489MetHis: 0.489 ± 0.027
1.188MetIle: 1.188 ± 0.05
1.241MetLys: 1.241 ± 0.043
2.578MetLeu: 2.578 ± 0.068
0.837MetMet: 0.837 ± 0.042
1.112MetAsn: 1.112 ± 0.045
1.233MetPro: 1.233 ± 0.041
1.092MetGln: 1.092 ± 0.046
1.394MetArg: 1.394 ± 0.046
1.449MetSer: 1.449 ± 0.045
1.151MetThr: 1.151 ± 0.043
1.579MetVal: 1.579 ± 0.052
0.249MetTrp: 0.249 ± 0.017
0.512MetTyr: 0.512 ± 0.031
0.0MetXaa: 0.0 ± 0.0
Asn
3.828AsnAla: 3.828 ± 0.08
0.352AsnCys: 0.352 ± 0.022
1.898AsnAsp: 1.898 ± 0.053
2.085AsnGlu: 2.085 ± 0.058
1.167AsnPhe: 1.167 ± 0.044
3.872AsnGly: 3.872 ± 0.089
1.162AsnHis: 1.162 ± 0.042
2.642AsnIle: 2.642 ± 0.09
1.939AsnLys: 1.939 ± 0.059
3.73AsnLeu: 3.73 ± 0.079
0.899AsnMet: 0.899 ± 0.036
1.753AsnAsn: 1.753 ± 0.067
2.361AsnPro: 2.361 ± 0.069
1.901AsnGln: 1.901 ± 0.065
2.426AsnArg: 2.426 ± 0.068
1.962AsnSer: 1.962 ± 0.074
2.319AsnThr: 2.319 ± 0.07
2.486AsnVal: 2.486 ± 0.082
0.57AsnTrp: 0.57 ± 0.033
1.064AsnTyr: 1.064 ± 0.047
0.0AsnXaa: 0.0 ± 0.0
Pro
5.342ProAla: 5.342 ± 0.13
0.377ProCys: 0.377 ± 0.029
3.077ProAsp: 3.077 ± 0.065
3.733ProGlu: 3.733 ± 0.081
1.875ProPhe: 1.875 ± 0.052
1.337ProGly: 1.337 ± 0.051
1.26ProHis: 1.26 ± 0.041
1.863ProIle: 1.863 ± 0.056
1.958ProLys: 1.958 ± 0.063
4.088ProLeu: 4.088 ± 0.082
1.047ProMet: 1.047 ± 0.036
1.753ProAsn: 1.753 ± 0.053
2.238ProPro: 2.238 ± 0.09
2.394ProGln: 2.394 ± 0.069
1.894ProArg: 1.894 ± 0.06
2.058ProSer: 2.058 ± 0.062
1.952ProThr: 1.952 ± 0.058
3.693ProVal: 3.693 ± 0.081
0.434ProTrp: 0.434 ± 0.028
1.352ProTyr: 1.352 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
6.075GlnAla: 6.075 ± 0.125
0.378GlnCys: 0.378 ± 0.023
2.151GlnAsp: 2.151 ± 0.062
2.255GlnGlu: 2.255 ± 0.078
1.441GlnPhe: 1.441 ± 0.05
3.422GlnGly: 3.422 ± 0.08
1.54GlnHis: 1.54 ± 0.052
2.857GlnIle: 2.857 ± 0.067
2.242GlnLys: 2.242 ± 0.069
4.366GlnLeu: 4.366 ± 0.097
1.149GlnMet: 1.149 ± 0.041
2.458GlnAsn: 2.458 ± 0.07
1.908GlnPro: 1.908 ± 0.058
3.488GlnGln: 3.488 ± 0.128
2.867GlnArg: 2.867 ± 0.075
2.765GlnSer: 2.765 ± 0.077
3.082GlnThr: 3.082 ± 0.092
2.678GlnVal: 2.678 ± 0.066
0.767GlnTrp: 0.767 ± 0.033
1.497GlnTyr: 1.497 ± 0.053
0.0GlnXaa: 0.0 ± 0.0
Arg
5.419ArgAla: 5.419 ± 0.103
0.512ArgCys: 0.512 ± 0.029
2.976ArgAsp: 2.976 ± 0.067
3.601ArgGlu: 3.601 ± 0.079
2.913ArgPhe: 2.913 ± 0.064
3.303ArgGly: 3.303 ± 0.075
1.742ArgHis: 1.742 ± 0.049
3.322ArgIle: 3.322 ± 0.073
2.288ArgLys: 2.288 ± 0.068
6.346ArgLeu: 6.346 ± 0.133
1.283ArgMet: 1.283 ± 0.049
2.039ArgAsn: 2.039 ± 0.053
2.355ArgPro: 2.355 ± 0.063
3.07ArgGln: 3.07 ± 0.065
3.747ArgArg: 3.747 ± 0.097
2.979ArgSer: 2.979 ± 0.066
2.461ArgThr: 2.461 ± 0.061
3.627ArgVal: 3.627 ± 0.077
0.696ArgTrp: 0.696 ± 0.036
2.137ArgTyr: 2.137 ± 0.061
0.0ArgXaa: 0.0 ± 0.0
Ser
5.941SerAla: 5.941 ± 0.107
0.583SerCys: 0.583 ± 0.035
3.116SerAsp: 3.116 ± 0.086
3.266SerGlu: 3.266 ± 0.091
2.006SerPhe: 2.006 ± 0.058
4.936SerGly: 4.936 ± 0.103
1.444SerHis: 1.444 ± 0.051
2.539SerIle: 2.539 ± 0.074
2.281SerLys: 2.281 ± 0.065
5.331SerLeu: 5.331 ± 0.103
1.127SerMet: 1.127 ± 0.043
1.934SerAsn: 1.934 ± 0.072
2.542SerPro: 2.542 ± 0.068
2.343SerGln: 2.343 ± 0.063
3.215SerArg: 3.215 ± 0.066
2.883SerSer: 2.883 ± 0.088
2.352SerThr: 2.352 ± 0.069
4.115SerVal: 4.115 ± 0.09
0.589SerTrp: 0.589 ± 0.031
1.546SerTyr: 1.546 ± 0.059
0.0SerXaa: 0.0 ± 0.0
Thr
6.488ThrAla: 6.488 ± 0.135
0.351ThrCys: 0.351 ± 0.025
2.828ThrAsp: 2.828 ± 0.071
2.694ThrGlu: 2.694 ± 0.072
1.778ThrPhe: 1.778 ± 0.051
3.965ThrGly: 3.965 ± 0.086
1.254ThrHis: 1.254 ± 0.039
2.181ThrIle: 2.181 ± 0.057
1.428ThrLys: 1.428 ± 0.049
5.918ThrLeu: 5.918 ± 0.102
0.85ThrMet: 0.85 ± 0.036
1.415ThrAsn: 1.415 ± 0.063
3.148ThrPro: 3.148 ± 0.075
2.101ThrGln: 2.101 ± 0.063
2.651ThrArg: 2.651 ± 0.058
1.927ThrSer: 1.927 ± 0.057
2.272ThrThr: 2.272 ± 0.078
4.974ThrVal: 4.974 ± 0.123
0.573ThrTrp: 0.573 ± 0.026
1.16ThrTyr: 1.16 ± 0.044
0.0ThrXaa: 0.0 ± 0.0
Val
7.006ValAla: 7.006 ± 0.126
1.085ValCys: 1.085 ± 0.043
2.997ValAsp: 2.997 ± 0.071
3.633ValGlu: 3.633 ± 0.083
3.095ValPhe: 3.095 ± 0.083
4.372ValGly: 4.372 ± 0.093
1.46ValHis: 1.46 ± 0.043
3.292ValIle: 3.292 ± 0.07
3.189ValLys: 3.189 ± 0.077
8.118ValLeu: 8.118 ± 0.121
1.788ValMet: 1.788 ± 0.06
2.403ValAsn: 2.403 ± 0.073
2.805ValPro: 2.805 ± 0.064
2.829ValGln: 2.829 ± 0.064
4.424ValArg: 4.424 ± 0.089
4.758ValSer: 4.758 ± 0.1
2.602ValThr: 2.602 ± 0.087
4.704ValVal: 4.704 ± 0.105
1.18ValTrp: 1.18 ± 0.044
2.206ValTyr: 2.206 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
1.185TrpAla: 1.185 ± 0.041
0.149TrpCys: 0.149 ± 0.014
0.634TrpAsp: 0.634 ± 0.031
0.558TrpGlu: 0.558 ± 0.03
0.664TrpPhe: 0.664 ± 0.032
0.796TrpGly: 0.796 ± 0.036
0.516TrpHis: 0.516 ± 0.032
0.571TrpIle: 0.571 ± 0.028
0.489TrpLys: 0.489 ± 0.027
2.177TrpLeu: 2.177 ± 0.075
0.239TrpMet: 0.239 ± 0.018
0.377TrpAsn: 0.377 ± 0.023
0.197TrpPro: 0.197 ± 0.017
1.436TrpGln: 1.436 ± 0.054
1.06TrpArg: 1.06 ± 0.047
0.551TrpSer: 0.551 ± 0.03
0.593TrpThr: 0.593 ± 0.038
0.947TrpVal: 0.947 ± 0.037
0.254TrpTrp: 0.254 ± 0.021
0.358TrpTyr: 0.358 ± 0.028
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.031TyrAla: 3.031 ± 0.063
0.363TyrCys: 0.363 ± 0.023
1.511TyrAsp: 1.511 ± 0.047
1.414TyrGlu: 1.414 ± 0.05
1.437TyrPhe: 1.437 ± 0.05
2.332TyrGly: 2.332 ± 0.057
0.814TyrHis: 0.814 ± 0.039
1.468TyrIle: 1.468 ± 0.051
0.918TyrLys: 0.918 ± 0.037
3.187TyrLeu: 3.187 ± 0.079
0.45TyrMet: 0.45 ± 0.026
0.95TyrAsn: 0.95 ± 0.037
1.46TyrPro: 1.46 ± 0.043
1.585TyrGln: 1.585 ± 0.053
2.378TyrArg: 2.378 ± 0.064
1.599TyrSer: 1.599 ± 0.049
1.643TyrThr: 1.643 ± 0.061
1.649TyrVal: 1.649 ± 0.054
0.451TyrTrp: 0.451 ± 0.027
0.969TyrTyr: 0.969 ± 0.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2247 proteins (689593 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski