Amino acid dipepetide frequency for Staphylococcus virus 71

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.719AlaAla: 0.719 ± 0.19
0.288AlaCys: 0.288 ± 0.125
2.518AlaAsp: 2.518 ± 0.388
4.172AlaGlu: 4.172 ± 0.596
2.733AlaPhe: 2.733 ± 0.439
3.309AlaGly: 3.309 ± 0.697
1.295AlaHis: 1.295 ± 0.328
5.755AlaIle: 5.755 ± 0.669
6.33AlaLys: 6.33 ± 0.702
4.891AlaLeu: 4.891 ± 0.724
1.654AlaMet: 1.654 ± 0.438
3.884AlaAsn: 3.884 ± 0.42
1.942AlaPro: 1.942 ± 0.348
2.805AlaGln: 2.805 ± 0.389
2.518AlaArg: 2.518 ± 0.369
3.812AlaSer: 3.812 ± 0.677
4.1AlaThr: 4.1 ± 0.59
3.74AlaVal: 3.74 ± 0.589
0.935AlaTrp: 0.935 ± 0.262
2.374AlaTyr: 2.374 ± 0.425
0.0AlaXaa: 0.0 ± 0.0
Cys
0.216CysAla: 0.216 ± 0.118
0.0CysCys: 0.0 ± 0.0
0.072CysAsp: 0.072 ± 0.063
0.216CysGlu: 0.216 ± 0.175
0.432CysPhe: 0.432 ± 0.155
0.144CysGly: 0.144 ± 0.102
0.072CysHis: 0.072 ± 0.072
0.144CysIle: 0.144 ± 0.11
0.432CysLys: 0.432 ± 0.168
0.216CysLeu: 0.216 ± 0.114
0.144CysMet: 0.144 ± 0.112
0.216CysAsn: 0.216 ± 0.124
0.144CysPro: 0.144 ± 0.084
0.144CysGln: 0.144 ± 0.095
0.432CysArg: 0.432 ± 0.213
0.288CysSer: 0.288 ± 0.162
0.072CysThr: 0.072 ± 0.069
0.288CysVal: 0.288 ± 0.142
0.072CysTrp: 0.072 ± 0.067
0.36CysTyr: 0.36 ± 0.161
0.0CysXaa: 0.0 ± 0.0
Asp
4.1AspAla: 4.1 ± 0.557
0.288AspCys: 0.288 ± 0.153
4.748AspAsp: 4.748 ± 0.71
4.891AspGlu: 4.891 ± 0.757
3.165AspPhe: 3.165 ± 0.527
4.244AspGly: 4.244 ± 0.649
0.432AspHis: 0.432 ± 0.164
4.819AspIle: 4.819 ± 0.498
6.546AspLys: 6.546 ± 0.886
4.891AspLeu: 4.891 ± 0.568
1.942AspMet: 1.942 ± 0.399
3.597AspAsn: 3.597 ± 0.563
1.151AspPro: 1.151 ± 0.321
1.007AspGln: 1.007 ± 0.268
1.87AspArg: 1.87 ± 0.358
3.74AspSer: 3.74 ± 0.521
3.381AspThr: 3.381 ± 0.404
4.1AspVal: 4.1 ± 0.634
0.647AspTrp: 0.647 ± 0.201
2.805AspTyr: 2.805 ± 0.468
0.0AspXaa: 0.0 ± 0.0
Glu
4.316GluAla: 4.316 ± 0.644
0.504GluCys: 0.504 ± 0.19
3.669GluAsp: 3.669 ± 0.527
5.683GluGlu: 5.683 ± 0.969
3.093GluPhe: 3.093 ± 0.451
3.021GluGly: 3.021 ± 0.487
1.511GluHis: 1.511 ± 0.337
5.035GluIle: 5.035 ± 0.664
5.467GluLys: 5.467 ± 0.772
7.913GluLeu: 7.913 ± 0.87
1.798GluMet: 1.798 ± 0.353
4.388GluAsn: 4.388 ± 0.451
1.87GluPro: 1.87 ± 0.337
3.956GluGln: 3.956 ± 0.608
3.597GluArg: 3.597 ± 0.603
3.525GluSer: 3.525 ± 0.522
3.74GluThr: 3.74 ± 0.531
4.676GluVal: 4.676 ± 0.524
0.863GluTrp: 0.863 ± 0.265
3.74GluTyr: 3.74 ± 0.561
0.0GluXaa: 0.0 ± 0.0
Phe
1.942PheAla: 1.942 ± 0.393
0.432PheCys: 0.432 ± 0.162
3.453PheAsp: 3.453 ± 0.387
3.381PheGlu: 3.381 ± 0.587
1.511PhePhe: 1.511 ± 0.423
2.733PheGly: 2.733 ± 0.546
0.935PheHis: 0.935 ± 0.252
4.388PheIle: 4.388 ± 0.598
3.597PheLys: 3.597 ± 0.397
2.805PheLeu: 2.805 ± 0.398
1.007PheMet: 1.007 ± 0.263
3.381PheAsn: 3.381 ± 0.464
1.007PhePro: 1.007 ± 0.278
1.151PheGln: 1.151 ± 0.255
1.511PheArg: 1.511 ± 0.316
2.59PheSer: 2.59 ± 0.41
3.165PheThr: 3.165 ± 0.517
3.021PheVal: 3.021 ± 0.464
0.36PheTrp: 0.36 ± 0.145
2.086PheTyr: 2.086 ± 0.373
0.0PheXaa: 0.0 ± 0.0
Gly
3.74GlyAla: 3.74 ± 0.617
0.144GlyCys: 0.144 ± 0.099
3.525GlyAsp: 3.525 ± 0.651
3.74GlyGlu: 3.74 ± 0.574
2.877GlyPhe: 2.877 ± 0.475
3.309GlyGly: 3.309 ± 0.525
1.439GlyHis: 1.439 ± 0.357
4.676GlyIle: 4.676 ± 0.429
4.891GlyLys: 4.891 ± 0.507
4.316GlyLeu: 4.316 ± 0.666
1.798GlyMet: 1.798 ± 0.308
3.021GlyAsn: 3.021 ± 0.435
0.288GlyPro: 0.288 ± 0.138
2.518GlyGln: 2.518 ± 0.361
2.23GlyArg: 2.23 ± 0.379
2.805GlySer: 2.805 ± 0.462
3.812GlyThr: 3.812 ± 0.599
4.676GlyVal: 4.676 ± 0.747
0.863GlyTrp: 0.863 ± 0.228
3.165GlyTyr: 3.165 ± 0.478
0.0GlyXaa: 0.0 ± 0.0
His
1.367HisAla: 1.367 ± 0.28
0.144HisCys: 0.144 ± 0.098
0.791HisAsp: 0.791 ± 0.216
0.863HisGlu: 0.863 ± 0.249
0.935HisPhe: 0.935 ± 0.237
1.367HisGly: 1.367 ± 0.307
0.719HisHis: 0.719 ± 0.214
1.295HisIle: 1.295 ± 0.283
1.079HisLys: 1.079 ± 0.285
1.367HisLeu: 1.367 ± 0.308
0.216HisMet: 0.216 ± 0.1
0.935HisAsn: 0.935 ± 0.282
0.719HisPro: 0.719 ± 0.268
1.223HisGln: 1.223 ± 0.31
0.36HisArg: 0.36 ± 0.163
1.079HisSer: 1.079 ± 0.274
1.007HisThr: 1.007 ± 0.272
0.935HisVal: 0.935 ± 0.197
0.072HisTrp: 0.072 ± 0.071
1.223HisTyr: 1.223 ± 0.331
0.0HisXaa: 0.0 ± 0.0
Ile
5.395IleAla: 5.395 ± 0.647
0.216IleCys: 0.216 ± 0.129
5.467IleAsp: 5.467 ± 0.655
5.826IleGlu: 5.826 ± 0.77
3.597IlePhe: 3.597 ± 0.629
5.251IleGly: 5.251 ± 0.749
1.007IleHis: 1.007 ± 0.232
4.028IleIle: 4.028 ± 0.557
7.769IleLys: 7.769 ± 0.766
4.388IleLeu: 4.388 ± 0.607
2.518IleMet: 2.518 ± 0.409
5.323IleAsn: 5.323 ± 0.78
2.23IlePro: 2.23 ± 0.322
2.877IleGln: 2.877 ± 0.439
3.669IleArg: 3.669 ± 0.543
4.963IleSer: 4.963 ± 0.563
6.33IleThr: 6.33 ± 0.593
4.388IleVal: 4.388 ± 0.427
1.295IleTrp: 1.295 ± 0.305
2.302IleTyr: 2.302 ± 0.492
0.0IleXaa: 0.0 ± 0.0
Lys
5.898LysAla: 5.898 ± 0.552
0.144LysCys: 0.144 ± 0.082
5.826LysAsp: 5.826 ± 0.766
7.337LysGlu: 7.337 ± 0.871
3.956LysPhe: 3.956 ± 0.587
4.891LysGly: 4.891 ± 0.738
2.23LysHis: 2.23 ± 0.408
6.618LysIle: 6.618 ± 0.859
7.553LysLys: 7.553 ± 0.88
6.474LysLeu: 6.474 ± 0.777
3.093LysMet: 3.093 ± 0.479
4.819LysAsn: 4.819 ± 0.607
2.733LysPro: 2.733 ± 0.525
4.532LysGln: 4.532 ± 0.708
4.46LysArg: 4.46 ± 0.647
4.891LysSer: 4.891 ± 0.522
5.611LysThr: 5.611 ± 0.712
5.683LysVal: 5.683 ± 0.639
0.719LysTrp: 0.719 ± 0.196
3.812LysTyr: 3.812 ± 0.619
0.0LysXaa: 0.0 ± 0.0
Leu
4.244LeuAla: 4.244 ± 0.663
0.216LeuCys: 0.216 ± 0.113
5.395LeuAsp: 5.395 ± 0.691
6.042LeuGlu: 6.042 ± 0.738
3.453LeuPhe: 3.453 ± 0.499
3.093LeuGly: 3.093 ± 0.488
0.791LeuHis: 0.791 ± 0.268
5.755LeuIle: 5.755 ± 0.633
7.337LeuLys: 7.337 ± 0.775
4.819LeuLeu: 4.819 ± 0.592
1.654LeuMet: 1.654 ± 0.424
5.539LeuAsn: 5.539 ± 0.433
2.014LeuPro: 2.014 ± 0.317
2.949LeuGln: 2.949 ± 0.404
3.381LeuArg: 3.381 ± 0.523
4.676LeuSer: 4.676 ± 0.464
5.179LeuThr: 5.179 ± 0.715
3.884LeuVal: 3.884 ± 0.604
0.504LeuTrp: 0.504 ± 0.193
3.237LeuTyr: 3.237 ± 0.644
0.0LeuXaa: 0.0 ± 0.0
Met
1.798MetAla: 1.798 ± 0.435
0.144MetCys: 0.144 ± 0.101
1.223MetAsp: 1.223 ± 0.379
1.726MetGlu: 1.726 ± 0.39
1.367MetPhe: 1.367 ± 0.311
1.007MetGly: 1.007 ± 0.245
0.36MetHis: 0.36 ± 0.177
1.511MetIle: 1.511 ± 0.326
2.302MetLys: 2.302 ± 0.441
2.59MetLeu: 2.59 ± 0.516
1.079MetMet: 1.079 ± 0.291
1.942MetAsn: 1.942 ± 0.438
1.151MetPro: 1.151 ± 0.231
1.583MetGln: 1.583 ± 0.392
1.295MetArg: 1.295 ± 0.293
1.942MetSer: 1.942 ± 0.431
1.798MetThr: 1.798 ± 0.351
0.863MetVal: 0.863 ± 0.229
0.432MetTrp: 0.432 ± 0.154
1.079MetTyr: 1.079 ± 0.261
0.0MetXaa: 0.0 ± 0.0
Asn
4.028AsnAla: 4.028 ± 0.582
0.144AsnCys: 0.144 ± 0.102
4.891AsnAsp: 4.891 ± 0.537
4.891AsnGlu: 4.891 ± 0.539
2.949AsnPhe: 2.949 ± 0.426
4.819AsnGly: 4.819 ± 0.727
0.863AsnHis: 0.863 ± 0.246
4.819AsnIle: 4.819 ± 0.523
6.186AsnLys: 6.186 ± 0.774
4.676AsnLeu: 4.676 ± 0.563
1.223AsnMet: 1.223 ± 0.258
5.107AsnAsn: 5.107 ± 0.651
2.805AsnPro: 2.805 ± 0.416
2.014AsnGln: 2.014 ± 0.308
2.877AsnArg: 2.877 ± 0.406
3.237AsnSer: 3.237 ± 0.479
2.661AsnThr: 2.661 ± 0.355
3.812AsnVal: 3.812 ± 0.587
0.935AsnTrp: 0.935 ± 0.259
2.374AsnTyr: 2.374 ± 0.435
0.0AsnXaa: 0.0 ± 0.0
Pro
1.367ProAla: 1.367 ± 0.267
0.072ProCys: 0.072 ± 0.079
1.583ProAsp: 1.583 ± 0.297
1.654ProGlu: 1.654 ± 0.328
1.295ProPhe: 1.295 ± 0.281
1.439ProGly: 1.439 ± 0.411
0.36ProHis: 0.36 ± 0.161
2.518ProIle: 2.518 ± 0.448
3.381ProLys: 3.381 ± 0.587
1.511ProLeu: 1.511 ± 0.336
0.863ProMet: 0.863 ± 0.254
1.726ProAsn: 1.726 ± 0.416
0.432ProPro: 0.432 ± 0.168
1.007ProGln: 1.007 ± 0.289
1.079ProArg: 1.079 ± 0.267
2.302ProSer: 2.302 ± 0.485
1.726ProThr: 1.726 ± 0.302
1.511ProVal: 1.511 ± 0.316
0.216ProTrp: 0.216 ± 0.155
1.295ProTyr: 1.295 ± 0.323
0.0ProXaa: 0.0 ± 0.0
Gln
3.381GlnAla: 3.381 ± 0.459
0.504GlnCys: 0.504 ± 0.21
1.798GlnAsp: 1.798 ± 0.398
2.518GlnGlu: 2.518 ± 0.517
1.942GlnPhe: 1.942 ± 0.384
2.158GlnGly: 2.158 ± 0.361
1.079GlnHis: 1.079 ± 0.25
2.733GlnIle: 2.733 ± 0.324
2.661GlnLys: 2.661 ± 0.386
2.733GlnLeu: 2.733 ± 0.484
1.079GlnMet: 1.079 ± 0.287
2.949GlnAsn: 2.949 ± 0.399
1.007GlnPro: 1.007 ± 0.265
2.374GlnGln: 2.374 ± 0.516
2.086GlnArg: 2.086 ± 0.358
2.446GlnSer: 2.446 ± 0.397
1.87GlnThr: 1.87 ± 0.365
2.661GlnVal: 2.661 ± 0.497
0.288GlnTrp: 0.288 ± 0.147
1.87GlnTyr: 1.87 ± 0.312
0.0GlnXaa: 0.0 ± 0.0
Arg
1.798ArgAla: 1.798 ± 0.327
0.216ArgCys: 0.216 ± 0.125
2.877ArgAsp: 2.877 ± 0.479
3.884ArgGlu: 3.884 ± 0.58
1.942ArgPhe: 1.942 ± 0.361
2.446ArgGly: 2.446 ± 0.409
1.079ArgHis: 1.079 ± 0.294
3.093ArgIle: 3.093 ± 0.43
3.525ArgLys: 3.525 ± 0.554
3.021ArgLeu: 3.021 ± 0.488
0.863ArgMet: 0.863 ± 0.218
2.59ArgAsn: 2.59 ± 0.404
1.151ArgPro: 1.151 ± 0.28
2.086ArgGln: 2.086 ± 0.358
1.295ArgArg: 1.295 ± 0.274
1.511ArgSer: 1.511 ± 0.362
1.798ArgThr: 1.798 ± 0.424
2.59ArgVal: 2.59 ± 0.375
0.647ArgTrp: 0.647 ± 0.223
2.23ArgTyr: 2.23 ± 0.385
0.0ArgXaa: 0.0 ± 0.0
Ser
3.956SerAla: 3.956 ± 0.601
0.072SerCys: 0.072 ± 0.08
4.388SerAsp: 4.388 ± 0.645
2.733SerGlu: 2.733 ± 0.471
2.661SerPhe: 2.661 ± 0.414
4.172SerGly: 4.172 ± 0.592
0.719SerHis: 0.719 ± 0.199
5.826SerIle: 5.826 ± 0.626
5.467SerLys: 5.467 ± 0.508
4.028SerLeu: 4.028 ± 0.537
1.87SerMet: 1.87 ± 0.338
4.604SerAsn: 4.604 ± 0.594
1.295SerPro: 1.295 ± 0.31
2.158SerGln: 2.158 ± 0.404
1.511SerArg: 1.511 ± 0.253
3.669SerSer: 3.669 ± 0.553
3.884SerThr: 3.884 ± 0.421
3.669SerVal: 3.669 ± 0.554
0.791SerTrp: 0.791 ± 0.172
2.086SerTyr: 2.086 ± 0.401
0.0SerXaa: 0.0 ± 0.0
Thr
3.525ThrAla: 3.525 ± 0.614
0.072ThrCys: 0.072 ± 0.08
3.812ThrAsp: 3.812 ± 0.437
3.165ThrGlu: 3.165 ± 0.433
2.518ThrPhe: 2.518 ± 0.503
4.028ThrGly: 4.028 ± 0.794
1.367ThrHis: 1.367 ± 0.269
6.258ThrIle: 6.258 ± 0.767
5.611ThrLys: 5.611 ± 0.607
4.316ThrLeu: 4.316 ± 0.449
1.511ThrMet: 1.511 ± 0.39
4.1ThrAsn: 4.1 ± 0.605
1.87ThrPro: 1.87 ± 0.329
2.086ThrGln: 2.086 ± 0.4
2.014ThrArg: 2.014 ± 0.339
4.532ThrSer: 4.532 ± 0.821
3.669ThrThr: 3.669 ± 0.497
3.381ThrVal: 3.381 ± 0.502
0.791ThrTrp: 0.791 ± 0.263
2.302ThrTyr: 2.302 ± 0.39
0.0ThrXaa: 0.0 ± 0.0
Val
4.819ValAla: 4.819 ± 0.669
0.216ValCys: 0.216 ± 0.111
4.1ValAsp: 4.1 ± 0.617
5.611ValGlu: 5.611 ± 0.649
2.014ValPhe: 2.014 ± 0.365
3.237ValGly: 3.237 ± 0.637
0.288ValHis: 0.288 ± 0.141
4.819ValIle: 4.819 ± 0.545
6.114ValLys: 6.114 ± 0.608
4.604ValLeu: 4.604 ± 0.576
1.726ValMet: 1.726 ± 0.359
3.381ValAsn: 3.381 ± 0.46
2.302ValPro: 2.302 ± 0.386
1.079ValGln: 1.079 ± 0.33
2.302ValArg: 2.302 ± 0.361
3.956ValSer: 3.956 ± 0.583
3.884ValThr: 3.884 ± 0.517
4.028ValVal: 4.028 ± 0.637
0.575ValTrp: 0.575 ± 0.204
2.23ValTyr: 2.23 ± 0.421
0.0ValXaa: 0.0 ± 0.0
Trp
1.007TrpAla: 1.007 ± 0.247
0.072TrpCys: 0.072 ± 0.067
0.504TrpAsp: 0.504 ± 0.188
0.791TrpGlu: 0.791 ± 0.182
0.432TrpPhe: 0.432 ± 0.157
0.647TrpGly: 0.647 ± 0.241
0.36TrpHis: 0.36 ± 0.142
1.079TrpIle: 1.079 ± 0.309
1.007TrpLys: 1.007 ± 0.279
1.151TrpLeu: 1.151 ± 0.335
0.288TrpMet: 0.288 ± 0.137
0.791TrpAsn: 0.791 ± 0.242
0.0TrpPro: 0.0 ± 0.0
0.504TrpGln: 0.504 ± 0.202
0.36TrpArg: 0.36 ± 0.136
0.719TrpSer: 0.719 ± 0.224
1.079TrpThr: 1.079 ± 0.23
0.791TrpVal: 0.791 ± 0.187
0.144TrpTrp: 0.144 ± 0.1
0.432TrpTyr: 0.432 ± 0.194
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.158TyrAla: 2.158 ± 0.351
0.216TyrCys: 0.216 ± 0.124
1.798TyrAsp: 1.798 ± 0.359
3.237TyrGlu: 3.237 ± 0.552
1.583TyrPhe: 1.583 ± 0.429
2.518TyrGly: 2.518 ± 0.451
0.791TyrHis: 0.791 ± 0.23
3.669TyrIle: 3.669 ± 0.516
4.028TyrLys: 4.028 ± 0.563
3.453TyrLeu: 3.453 ± 0.435
0.791TyrMet: 0.791 ± 0.192
3.021TyrAsn: 3.021 ± 0.511
1.223TyrPro: 1.223 ± 0.313
2.086TyrGln: 2.086 ± 0.351
1.798TyrArg: 1.798 ± 0.37
2.877TyrSer: 2.877 ± 0.469
2.158TyrThr: 2.158 ± 0.408
2.59TyrVal: 2.59 ± 0.44
1.007TyrTrp: 1.007 ± 0.372
1.583TyrTyr: 1.583 ± 0.387
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 72 proteins (13903 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski