Amino acid dipepetide frequency for Klebsiella phage ST13-OXA48phi12.4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.104AlaAla: 11.104 ± 1.101
1.36AlaCys: 1.36 ± 0.346
5.212AlaAsp: 5.212 ± 0.553
6.289AlaGlu: 6.289 ± 0.58
3.456AlaPhe: 3.456 ± 0.415
8.102AlaGly: 8.102 ± 0.616
1.36AlaHis: 1.36 ± 0.267
5.665AlaIle: 5.665 ± 0.482
4.702AlaLys: 4.702 ± 0.567
11.274AlaLeu: 11.274 ± 1.112
2.833AlaMet: 2.833 ± 0.382
2.663AlaAsn: 2.663 ± 0.375
3.059AlaPro: 3.059 ± 0.485
5.042AlaGln: 5.042 ± 0.725
5.949AlaArg: 5.949 ± 0.74
6.289AlaSer: 6.289 ± 0.758
5.609AlaThr: 5.609 ± 0.612
6.572AlaVal: 6.572 ± 0.587
1.756AlaTrp: 1.756 ± 0.278
2.153AlaTyr: 2.153 ± 0.36
0.0AlaXaa: 0.0 ± 0.0
Cys
0.623CysAla: 0.623 ± 0.166
0.17CysCys: 0.17 ± 0.107
0.963CysAsp: 0.963 ± 0.255
1.02CysGlu: 1.02 ± 0.249
0.51CysPhe: 0.51 ± 0.144
0.737CysGly: 0.737 ± 0.201
0.397CysHis: 0.397 ± 0.146
0.397CysIle: 0.397 ± 0.16
0.567CysLys: 0.567 ± 0.222
0.963CysLeu: 0.963 ± 0.255
0.17CysMet: 0.17 ± 0.101
0.397CysAsn: 0.397 ± 0.154
0.34CysPro: 0.34 ± 0.16
0.623CysGln: 0.623 ± 0.184
0.737CysArg: 0.737 ± 0.261
1.02CysSer: 1.02 ± 0.258
0.453CysThr: 0.453 ± 0.182
0.793CysVal: 0.793 ± 0.193
0.227CysTrp: 0.227 ± 0.109
0.737CysTyr: 0.737 ± 0.25
0.0CysXaa: 0.0 ± 0.0
Asp
5.325AspAla: 5.325 ± 0.495
0.51AspCys: 0.51 ± 0.181
4.136AspAsp: 4.136 ± 0.527
4.532AspGlu: 4.532 ± 0.503
2.493AspPhe: 2.493 ± 0.398
4.192AspGly: 4.192 ± 0.48
1.02AspHis: 1.02 ± 0.239
4.136AspIle: 4.136 ± 0.408
2.663AspLys: 2.663 ± 0.4
4.816AspLeu: 4.816 ± 0.469
1.36AspMet: 1.36 ± 0.283
2.379AspAsn: 2.379 ± 0.323
2.776AspPro: 2.776 ± 0.444
2.266AspGln: 2.266 ± 0.401
3.229AspArg: 3.229 ± 0.369
3.003AspSer: 3.003 ± 0.533
2.549AspThr: 2.549 ± 0.452
3.683AspVal: 3.683 ± 0.457
1.19AspTrp: 1.19 ± 0.217
1.586AspTyr: 1.586 ± 0.337
0.0AspXaa: 0.0 ± 0.0
Glu
5.779GluAla: 5.779 ± 0.538
0.906GluCys: 0.906 ± 0.234
2.663GluAsp: 2.663 ± 0.4
4.022GluGlu: 4.022 ± 0.423
2.266GluPhe: 2.266 ± 0.364
4.192GluGly: 4.192 ± 0.739
1.076GluHis: 1.076 ± 0.207
3.683GluIle: 3.683 ± 0.434
3.343GluLys: 3.343 ± 0.45
5.722GluLeu: 5.722 ± 0.563
1.756GluMet: 1.756 ± 0.266
3.626GluAsn: 3.626 ± 0.354
2.153GluPro: 2.153 ± 0.385
3.399GluGln: 3.399 ± 0.592
3.909GluArg: 3.909 ± 0.44
3.626GluSer: 3.626 ± 0.455
3.399GluThr: 3.399 ± 0.403
3.796GluVal: 3.796 ± 0.406
1.246GluTrp: 1.246 ± 0.24
2.153GluTyr: 2.153 ± 0.423
0.0GluXaa: 0.0 ± 0.0
Phe
3.683PheAla: 3.683 ± 0.533
0.567PheCys: 0.567 ± 0.19
2.379PheAsp: 2.379 ± 0.41
1.756PheGlu: 1.756 ± 0.289
1.246PhePhe: 1.246 ± 0.342
2.606PheGly: 2.606 ± 0.303
0.567PheHis: 0.567 ± 0.148
1.53PheIle: 1.53 ± 0.315
1.473PheLys: 1.473 ± 0.267
2.606PheLeu: 2.606 ± 0.385
0.737PheMet: 0.737 ± 0.197
1.53PheAsn: 1.53 ± 0.243
1.133PhePro: 1.133 ± 0.284
1.19PheGln: 1.19 ± 0.255
2.153PheArg: 2.153 ± 0.346
3.173PheSer: 3.173 ± 0.485
2.379PheThr: 2.379 ± 0.339
2.663PheVal: 2.663 ± 0.46
0.963PheTrp: 0.963 ± 0.224
1.076PheTyr: 1.076 ± 0.275
0.0PheXaa: 0.0 ± 0.0
Gly
5.835GlyAla: 5.835 ± 1.037
0.793GlyCys: 0.793 ± 0.219
4.192GlyAsp: 4.192 ± 0.569
4.136GlyGlu: 4.136 ± 0.433
3.116GlyPhe: 3.116 ± 0.396
5.042GlyGly: 5.042 ± 0.658
1.7GlyHis: 1.7 ± 0.302
4.476GlyIle: 4.476 ± 0.622
4.249GlyLys: 4.249 ± 0.67
6.515GlyLeu: 6.515 ± 0.807
2.776GlyMet: 2.776 ± 0.357
2.719GlyAsn: 2.719 ± 0.499
1.813GlyPro: 1.813 ± 0.335
2.776GlyGln: 2.776 ± 0.423
3.739GlyArg: 3.739 ± 0.384
4.192GlySer: 4.192 ± 0.538
3.513GlyThr: 3.513 ± 0.381
5.892GlyVal: 5.892 ± 0.694
1.473GlyTrp: 1.473 ± 0.331
2.719GlyTyr: 2.719 ± 0.386
0.0GlyXaa: 0.0 ± 0.0
His
0.906HisAla: 0.906 ± 0.201
0.51HisCys: 0.51 ± 0.159
1.246HisAsp: 1.246 ± 0.273
1.02HisGlu: 1.02 ± 0.206
0.737HisPhe: 0.737 ± 0.204
1.36HisGly: 1.36 ± 0.31
0.453HisHis: 0.453 ± 0.193
1.246HisIle: 1.246 ± 0.246
0.737HisLys: 0.737 ± 0.206
1.983HisLeu: 1.983 ± 0.37
0.397HisMet: 0.397 ± 0.149
0.51HisAsn: 0.51 ± 0.141
1.19HisPro: 1.19 ± 0.238
1.133HisGln: 1.133 ± 0.263
1.076HisArg: 1.076 ± 0.283
0.793HisSer: 0.793 ± 0.187
0.793HisThr: 0.793 ± 0.215
1.246HisVal: 1.246 ± 0.273
0.397HisTrp: 0.397 ± 0.15
0.68HisTyr: 0.68 ± 0.239
0.0HisXaa: 0.0 ± 0.0
Ile
5.099IleAla: 5.099 ± 0.534
0.453IleCys: 0.453 ± 0.126
4.532IleAsp: 4.532 ± 0.427
3.399IleGlu: 3.399 ± 0.458
2.493IlePhe: 2.493 ± 0.383
2.946IleGly: 2.946 ± 0.5
0.906IleHis: 0.906 ± 0.246
2.719IleIle: 2.719 ± 0.396
2.889IleLys: 2.889 ± 0.43
3.739IleLeu: 3.739 ± 0.48
0.793IleMet: 0.793 ± 0.188
3.003IleAsn: 3.003 ± 0.482
2.379IlePro: 2.379 ± 0.288
2.096IleGln: 2.096 ± 0.356
3.626IleArg: 3.626 ± 0.391
4.249IleSer: 4.249 ± 0.485
3.796IleThr: 3.796 ± 0.476
3.116IleVal: 3.116 ± 0.506
0.567IleTrp: 0.567 ± 0.171
1.53IleTyr: 1.53 ± 0.256
0.0IleXaa: 0.0 ± 0.0
Lys
5.609LysAla: 5.609 ± 0.616
0.68LysCys: 0.68 ± 0.194
1.983LysAsp: 1.983 ± 0.415
3.569LysGlu: 3.569 ± 0.505
1.303LysPhe: 1.303 ± 0.225
2.379LysGly: 2.379 ± 0.382
1.02LysHis: 1.02 ± 0.214
2.436LysIle: 2.436 ± 0.379
2.946LysLys: 2.946 ± 0.488
4.079LysLeu: 4.079 ± 0.475
1.303LysMet: 1.303 ± 0.277
2.266LysAsn: 2.266 ± 0.363
2.606LysPro: 2.606 ± 0.356
1.756LysGln: 1.756 ± 0.34
3.003LysArg: 3.003 ± 0.49
3.852LysSer: 3.852 ± 0.478
4.079LysThr: 4.079 ± 0.565
2.946LysVal: 2.946 ± 0.536
0.567LysTrp: 0.567 ± 0.175
1.303LysTyr: 1.303 ± 0.243
0.0LysXaa: 0.0 ± 0.0
Leu
9.688LeuAla: 9.688 ± 0.736
1.19LeuCys: 1.19 ± 0.293
5.722LeuAsp: 5.722 ± 0.517
4.986LeuGlu: 4.986 ± 0.631
3.173LeuPhe: 3.173 ± 0.548
6.062LeuGly: 6.062 ± 0.79
1.643LeuHis: 1.643 ± 0.303
4.702LeuIle: 4.702 ± 0.536
4.986LeuLys: 4.986 ± 0.522
8.951LeuLeu: 8.951 ± 0.851
2.04LeuMet: 2.04 ± 0.352
3.626LeuAsn: 3.626 ± 0.409
4.589LeuPro: 4.589 ± 0.589
3.003LeuGln: 3.003 ± 0.393
5.439LeuArg: 5.439 ± 0.584
6.515LeuSer: 6.515 ± 0.669
6.175LeuThr: 6.175 ± 0.545
4.589LeuVal: 4.589 ± 0.527
0.906LeuTrp: 0.906 ± 0.228
2.04LeuTyr: 2.04 ± 0.331
0.0LeuXaa: 0.0 ± 0.0
Met
3.003MetAla: 3.003 ± 0.452
0.227MetCys: 0.227 ± 0.118
1.416MetAsp: 1.416 ± 0.229
1.303MetGlu: 1.303 ± 0.285
0.623MetPhe: 0.623 ± 0.185
1.473MetGly: 1.473 ± 0.247
0.283MetHis: 0.283 ± 0.145
1.076MetIle: 1.076 ± 0.217
1.926MetLys: 1.926 ± 0.316
2.266MetLeu: 2.266 ± 0.381
0.51MetMet: 0.51 ± 0.142
0.963MetAsn: 0.963 ± 0.235
1.7MetPro: 1.7 ± 0.256
1.076MetGln: 1.076 ± 0.311
1.586MetArg: 1.586 ± 0.26
2.096MetSer: 2.096 ± 0.34
2.096MetThr: 2.096 ± 0.385
1.53MetVal: 1.53 ± 0.329
0.623MetTrp: 0.623 ± 0.188
0.51MetTyr: 0.51 ± 0.143
0.0MetXaa: 0.0 ± 0.0
Asn
4.022AsnAla: 4.022 ± 0.505
0.737AsnCys: 0.737 ± 0.225
2.379AsnAsp: 2.379 ± 0.295
2.663AsnGlu: 2.663 ± 0.35
1.246AsnPhe: 1.246 ± 0.223
4.022AsnGly: 4.022 ± 0.422
0.623AsnHis: 0.623 ± 0.173
1.87AsnIle: 1.87 ± 0.425
1.756AsnLys: 1.756 ± 0.263
2.549AsnLeu: 2.549 ± 0.358
0.85AsnMet: 0.85 ± 0.234
1.7AsnAsn: 1.7 ± 0.356
2.946AsnPro: 2.946 ± 0.338
1.586AsnGln: 1.586 ± 0.322
1.983AsnArg: 1.983 ± 0.328
2.153AsnSer: 2.153 ± 0.346
1.87AsnThr: 1.87 ± 0.288
1.813AsnVal: 1.813 ± 0.268
0.453AsnTrp: 0.453 ± 0.147
1.416AsnTyr: 1.416 ± 0.27
0.0AsnXaa: 0.0 ± 0.0
Pro
5.722ProAla: 5.722 ± 0.628
0.283ProCys: 0.283 ± 0.141
3.173ProAsp: 3.173 ± 0.592
3.569ProGlu: 3.569 ± 0.502
1.756ProPhe: 1.756 ± 0.305
2.946ProGly: 2.946 ± 0.439
0.793ProHis: 0.793 ± 0.25
1.643ProIle: 1.643 ± 0.36
1.643ProLys: 1.643 ± 0.254
3.456ProLeu: 3.456 ± 0.615
1.02ProMet: 1.02 ± 0.241
1.473ProAsn: 1.473 ± 0.296
1.87ProPro: 1.87 ± 0.313
2.266ProGln: 2.266 ± 0.435
1.926ProArg: 1.926 ± 0.286
2.663ProSer: 2.663 ± 0.373
1.926ProThr: 1.926 ± 0.297
3.683ProVal: 3.683 ± 0.512
0.623ProTrp: 0.623 ± 0.193
1.246ProTyr: 1.246 ± 0.265
0.0ProXaa: 0.0 ± 0.0
Gln
4.816GlnAla: 4.816 ± 0.766
0.17GlnCys: 0.17 ± 0.099
1.586GlnAsp: 1.586 ± 0.299
2.889GlnGlu: 2.889 ± 0.567
1.076GlnPhe: 1.076 ± 0.181
2.889GlnGly: 2.889 ± 0.303
0.906GlnHis: 0.906 ± 0.224
2.323GlnIle: 2.323 ± 0.357
2.493GlnLys: 2.493 ± 0.493
3.626GlnLeu: 3.626 ± 0.493
1.53GlnMet: 1.53 ± 0.284
1.303GlnAsn: 1.303 ± 0.348
2.153GlnPro: 2.153 ± 0.405
3.173GlnGln: 3.173 ± 0.567
3.909GlnArg: 3.909 ± 0.539
2.493GlnSer: 2.493 ± 0.478
2.153GlnThr: 2.153 ± 0.385
2.663GlnVal: 2.663 ± 0.409
0.85GlnTrp: 0.85 ± 0.204
1.303GlnTyr: 1.303 ± 0.272
0.0GlnXaa: 0.0 ± 0.0
Arg
6.742ArgAla: 6.742 ± 0.607
0.906ArgCys: 0.906 ± 0.259
3.003ArgAsp: 3.003 ± 0.453
3.569ArgGlu: 3.569 ± 0.497
1.983ArgPhe: 1.983 ± 0.35
3.909ArgGly: 3.909 ± 0.418
1.473ArgHis: 1.473 ± 0.287
3.456ArgIle: 3.456 ± 0.464
3.456ArgLys: 3.456 ± 0.473
5.382ArgLeu: 5.382 ± 0.68
2.096ArgMet: 2.096 ± 0.38
2.663ArgAsn: 2.663 ± 0.356
2.096ArgPro: 2.096 ± 0.341
2.946ArgGln: 2.946 ± 0.463
4.306ArgArg: 4.306 ± 0.416
2.436ArgSer: 2.436 ± 0.402
3.116ArgThr: 3.116 ± 0.386
4.306ArgVal: 4.306 ± 0.421
1.076ArgTrp: 1.076 ± 0.258
2.323ArgTyr: 2.323 ± 0.342
0.0ArgXaa: 0.0 ± 0.0
Ser
6.855SerAla: 6.855 ± 0.655
0.623SerCys: 0.623 ± 0.184
3.683SerAsp: 3.683 ± 0.422
4.079SerGlu: 4.079 ± 0.437
2.04SerPhe: 2.04 ± 0.464
6.175SerGly: 6.175 ± 0.765
0.906SerHis: 0.906 ± 0.304
3.286SerIle: 3.286 ± 0.49
2.379SerLys: 2.379 ± 0.367
5.609SerLeu: 5.609 ± 0.621
1.813SerMet: 1.813 ± 0.321
1.983SerAsn: 1.983 ± 0.33
3.116SerPro: 3.116 ± 0.382
2.549SerGln: 2.549 ± 0.564
3.909SerArg: 3.909 ± 0.412
4.192SerSer: 4.192 ± 0.765
3.852SerThr: 3.852 ± 0.409
4.022SerVal: 4.022 ± 0.517
0.906SerTrp: 0.906 ± 0.206
1.7SerTyr: 1.7 ± 0.325
0.0SerXaa: 0.0 ± 0.0
Thr
6.175ThrAla: 6.175 ± 0.658
0.453ThrCys: 0.453 ± 0.194
3.116ThrAsp: 3.116 ± 0.42
3.456ThrGlu: 3.456 ± 0.445
1.643ThrPhe: 1.643 ± 0.248
5.269ThrGly: 5.269 ± 0.555
1.133ThrHis: 1.133 ± 0.284
3.343ThrIle: 3.343 ± 0.459
1.926ThrLys: 1.926 ± 0.354
5.949ThrLeu: 5.949 ± 0.641
1.473ThrMet: 1.473 ± 0.253
1.813ThrAsn: 1.813 ± 0.306
3.059ThrPro: 3.059 ± 0.44
2.493ThrGln: 2.493 ± 0.363
3.456ThrArg: 3.456 ± 0.433
3.683ThrSer: 3.683 ± 0.553
2.549ThrThr: 2.549 ± 0.382
4.022ThrVal: 4.022 ± 0.575
1.246ThrTrp: 1.246 ± 0.23
1.643ThrTyr: 1.643 ± 0.336
0.0ThrXaa: 0.0 ± 0.0
Val
5.325ValAla: 5.325 ± 0.631
0.567ValCys: 0.567 ± 0.213
3.513ValAsp: 3.513 ± 0.368
4.362ValGlu: 4.362 ± 0.396
2.096ValPhe: 2.096 ± 0.382
3.173ValGly: 3.173 ± 0.423
1.246ValHis: 1.246 ± 0.263
3.909ValIle: 3.909 ± 0.473
3.683ValLys: 3.683 ± 0.525
6.062ValLeu: 6.062 ± 0.607
1.473ValMet: 1.473 ± 0.308
2.663ValAsn: 2.663 ± 0.453
2.606ValPro: 2.606 ± 0.336
2.606ValGln: 2.606 ± 0.355
4.136ValArg: 4.136 ± 0.527
5.156ValSer: 5.156 ± 0.485
4.532ValThr: 4.532 ± 0.519
5.269ValVal: 5.269 ± 0.64
1.19ValTrp: 1.19 ± 0.257
1.983ValTyr: 1.983 ± 0.277
0.0ValXaa: 0.0 ± 0.0
Trp
1.19TrpAla: 1.19 ± 0.222
0.17TrpCys: 0.17 ± 0.084
0.737TrpAsp: 0.737 ± 0.199
0.906TrpGlu: 0.906 ± 0.201
0.906TrpPhe: 0.906 ± 0.202
1.076TrpGly: 1.076 ± 0.254
0.227TrpHis: 0.227 ± 0.093
1.246TrpIle: 1.246 ± 0.314
0.68TrpLys: 0.68 ± 0.177
1.926TrpLeu: 1.926 ± 0.412
0.51TrpMet: 0.51 ± 0.215
0.623TrpAsn: 0.623 ± 0.205
0.906TrpPro: 0.906 ± 0.253
1.133TrpGln: 1.133 ± 0.251
1.19TrpArg: 1.19 ± 0.215
0.793TrpSer: 0.793 ± 0.178
0.963TrpThr: 0.963 ± 0.251
1.473TrpVal: 1.473 ± 0.245
0.057TrpTrp: 0.057 ± 0.062
0.397TrpTyr: 0.397 ± 0.142
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.946TyrAla: 2.946 ± 0.43
0.567TyrCys: 0.567 ± 0.19
2.21TyrAsp: 2.21 ± 0.351
1.19TyrGlu: 1.19 ± 0.223
1.246TyrPhe: 1.246 ± 0.229
3.116TyrGly: 3.116 ± 0.399
0.68TyrHis: 0.68 ± 0.256
1.19TyrIle: 1.19 ± 0.253
1.19TyrLys: 1.19 ± 0.243
2.549TyrLeu: 2.549 ± 0.343
0.793TyrMet: 0.793 ± 0.2
0.737TyrAsn: 0.737 ± 0.21
1.19TyrPro: 1.19 ± 0.259
1.19TyrGln: 1.19 ± 0.284
1.983TyrArg: 1.983 ± 0.338
1.303TyrSer: 1.303 ± 0.261
2.096TyrThr: 2.096 ± 0.325
1.53TyrVal: 1.53 ± 0.246
0.793TyrTrp: 0.793 ± 0.16
0.737TyrTyr: 0.737 ± 0.251
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 85 proteins (17652 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski