Amino acid dipepetide frequency for Marivita geojedonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.536AlaAla: 14.536 ± 0.155	1.145AlaCys: 1.145 ± 0.029	6.646AlaAsp: 6.646 ± 0.079	7.834AlaGlu: 7.834 ± 0.105	4.415AlaPhe: 4.415 ± 0.059	9.334AlaGly: 9.334 ± 0.114	2.286AlaHis: 2.286 ± 0.043	5.963AlaIle: 5.963 ± 0.074	3.895AlaLys: 3.895 ± 0.068	13.098AlaLeu: 13.098 ± 0.113	3.772AlaMet: 3.772 ± 0.062	2.821AlaAsn: 2.821 ± 0.049	5.185AlaPro: 5.185 ± 0.077	4.355AlaGln: 4.355 ± 0.07	7.916AlaArg: 7.916 ± 0.097	5.662AlaSer: 5.662 ± 0.067	5.695AlaThr: 5.695 ± 0.077	8.023AlaVal: 8.023 ± 0.091	1.428AlaTrp: 1.428 ± 0.037	2.632AlaTyr: 2.632 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	1.108CysAla: 1.108 ± 0.033	0.116CysCys: 0.116 ± 0.01	0.66CysAsp: 0.66 ± 0.021	0.468CysGlu: 0.468 ± 0.022	0.334CysPhe: 0.334 ± 0.017	0.984CysGly: 0.984 ± 0.031	0.285CysHis: 0.285 ± 0.018	0.437CysIle: 0.437 ± 0.022	0.221CysLys: 0.221 ± 0.014	0.896CysLeu: 0.896 ± 0.027	0.176CysMet: 0.176 ± 0.012	0.231CysAsn: 0.231 ± 0.013	0.546CysPro: 0.546 ± 0.023	0.255CysGln: 0.255 ± 0.014	0.543CysArg: 0.543 ± 0.024	0.489CysSer: 0.489 ± 0.017	0.48CysThr: 0.48 ± 0.021	0.705CysVal: 0.705 ± 0.027	0.105CysTrp: 0.105 ± 0.008	0.236CysTyr: 0.236 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	7.507AspAla: 7.507 ± 0.087	0.543AspCys: 0.543 ± 0.022	3.505AspAsp: 3.505 ± 0.072	3.721AspGlu: 3.721 ± 0.057	2.313AspPhe: 2.313 ± 0.048	5.591AspGly: 5.591 ± 0.077	1.436AspHis: 1.436 ± 0.038	3.249AspIle: 3.249 ± 0.049	1.755AspLys: 1.755 ± 0.047	6.446AspLeu: 6.446 ± 0.079	1.777AspMet: 1.777 ± 0.038	1.267AspAsn: 1.267 ± 0.035	3.639AspPro: 3.639 ± 0.061	2.007AspGln: 2.007 ± 0.044	4.312AspArg: 4.312 ± 0.068	2.272AspSer: 2.272 ± 0.051	3.237AspThr: 3.237 ± 0.055	4.605AspVal: 4.605 ± 0.079	1.213AspTrp: 1.213 ± 0.03	1.596AspTyr: 1.596 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.84GluAla: 7.84 ± 0.088	0.379GluCys: 0.379 ± 0.016	3.704GluAsp: 3.704 ± 0.055	3.611GluGlu: 3.611 ± 0.068	1.911GluPhe: 1.911 ± 0.045	4.589GluGly: 4.589 ± 0.072	1.184GluHis: 1.184 ± 0.031	3.738GluIle: 3.738 ± 0.066	2.314GluLys: 2.314 ± 0.045	5.241GluLeu: 5.241 ± 0.066	1.939GluMet: 1.939 ± 0.047	1.891GluAsn: 1.891 ± 0.04	2.593GluPro: 2.593 ± 0.061	2.062GluGln: 2.062 ± 0.044	4.183GluArg: 4.183 ± 0.075	2.268GluSer: 2.268 ± 0.046	4.034GluThr: 4.034 ± 0.063	4.476GluVal: 4.476 ± 0.061	0.776GluTrp: 0.776 ± 0.028	1.177GluTyr: 1.177 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.438PheAla: 4.438 ± 0.073	0.478PheCys: 0.478 ± 0.022	2.966PheAsp: 2.966 ± 0.057	2.393PheGlu: 2.393 ± 0.046	1.601PhePhe: 1.601 ± 0.041	3.833PheGly: 3.833 ± 0.067	0.798PheHis: 0.798 ± 0.027	1.794PheIle: 1.794 ± 0.045	1.051PheLys: 1.051 ± 0.033	3.644PheLeu: 3.644 ± 0.06	0.892PheMet: 0.892 ± 0.027	1.103PheAsn: 1.103 ± 0.033	1.614PhePro: 1.614 ± 0.036	1.076PheGln: 1.076 ± 0.033	2.222PheArg: 2.222 ± 0.042	2.191PheSer: 2.191 ± 0.042	2.119PheThr: 2.119 ± 0.043	2.889PheVal: 2.889 ± 0.052	0.603PheTrp: 0.603 ± 0.023	0.956PheTyr: 0.956 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.141GlyAla: 9.141 ± 0.093	0.874GlyCys: 0.874 ± 0.028	4.681GlyAsp: 4.681 ± 0.077	4.451GlyGlu: 4.451 ± 0.068	3.783GlyPhe: 3.783 ± 0.059	6.979GlyGly: 6.979 ± 0.101	1.895GlyHis: 1.895 ± 0.047	4.561GlyIle: 4.561 ± 0.064	3.213GlyLys: 3.213 ± 0.058	9.009GlyLeu: 9.009 ± 0.109	2.638GlyMet: 2.638 ± 0.055	2.045GlyAsn: 2.045 ± 0.049	3.657GlyPro: 3.657 ± 0.064	3.1GlyGln: 3.1 ± 0.055	5.213GlyArg: 5.213 ± 0.063	4.43GlySer: 4.43 ± 0.07	4.695GlyThr: 4.695 ± 0.067	6.509GlyVal: 6.509 ± 0.069	1.477GlyTrp: 1.477 ± 0.041	2.332GlyTyr: 2.332 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	2.288HisAla: 2.288 ± 0.044	0.25HisCys: 0.25 ± 0.014	1.271HisAsp: 1.271 ± 0.033	1.117HisGlu: 1.117 ± 0.031	0.832HisPhe: 0.832 ± 0.027	1.854HisGly: 1.854 ± 0.046	0.578HisHis: 0.578 ± 0.025	1.046HisIle: 1.046 ± 0.033	0.577HisLys: 0.577 ± 0.023	2.132HisLeu: 2.132 ± 0.047	0.589HisMet: 0.589 ± 0.022	0.484HisAsn: 0.484 ± 0.018	1.397HisPro: 1.397 ± 0.035	0.586HisGln: 0.586 ± 0.022	1.333HisArg: 1.333 ± 0.044	0.975HisSer: 0.975 ± 0.027	0.904HisThr: 0.904 ± 0.028	1.626HisVal: 1.626 ± 0.035	0.336HisTrp: 0.336 ± 0.018	0.516HisTyr: 0.516 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.041IleAla: 7.041 ± 0.087	0.637IleCys: 0.637 ± 0.026	3.715IleAsp: 3.715 ± 0.057	3.62IleGlu: 3.62 ± 0.056	1.811IlePhe: 1.811 ± 0.04	4.967IleGly: 4.967 ± 0.064	0.914IleHis: 0.914 ± 0.027	2.39IleIle: 2.39 ± 0.055	1.562IleLys: 1.562 ± 0.043	4.968IleLeu: 4.968 ± 0.07	1.123IleMet: 1.123 ± 0.033	1.451IleAsn: 1.451 ± 0.038	2.524IlePro: 2.524 ± 0.041	1.267IleGln: 1.267 ± 0.037	3.221IleArg: 3.221 ± 0.053	3.092IleSer: 3.092 ± 0.055	3.106IleThr: 3.106 ± 0.056	3.928IleVal: 3.928 ± 0.056	0.768IleTrp: 0.768 ± 0.026	1.209IleTyr: 1.209 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	4.058LysAla: 4.058 ± 0.064	0.219LysCys: 0.219 ± 0.012	2.001LysAsp: 2.001 ± 0.044	1.721LysGlu: 1.721 ± 0.041	0.969LysPhe: 0.969 ± 0.03	2.774LysGly: 2.774 ± 0.049	0.653LysHis: 0.653 ± 0.027	1.651LysIle: 1.651 ± 0.044	1.267LysLys: 1.267 ± 0.033	3.115LysLeu: 3.115 ± 0.051	0.917LysMet: 0.917 ± 0.031	0.864LysAsn: 0.864 ± 0.028	1.933LysPro: 1.933 ± 0.043	0.943LysGln: 0.943 ± 0.03	2.373LysArg: 2.373 ± 0.051	2.04LysSer: 2.04 ± 0.045	2.135LysThr: 2.135 ± 0.044	2.378LysVal: 2.378 ± 0.044	0.415LysTrp: 0.415 ± 0.018	0.682LysTyr: 0.682 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	11.752LeuAla: 11.752 ± 0.117	1.007LeuCys: 1.007 ± 0.027	5.998LeuAsp: 5.998 ± 0.076	5.602LeuGlu: 5.602 ± 0.073	3.718LeuPhe: 3.718 ± 0.066	8.293LeuGly: 8.293 ± 0.1	1.888LeuHis: 1.888 ± 0.042	5.401LeuIle: 5.401 ± 0.09	3.315LeuLys: 3.315 ± 0.049	8.831LeuLeu: 8.831 ± 0.123	2.743LeuMet: 2.743 ± 0.052	2.879LeuAsn: 2.879 ± 0.049	5.386LeuPro: 5.386 ± 0.079	2.744LeuGln: 2.744 ± 0.053	6.808LeuArg: 6.808 ± 0.085	6.914LeuSer: 6.914 ± 0.084	6.135LeuThr: 6.135 ± 0.08	6.767LeuVal: 6.767 ± 0.082	1.333LeuTrp: 1.333 ± 0.038	2.065LeuTyr: 2.065 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.469MetAla: 3.469 ± 0.054	0.217MetCys: 0.217 ± 0.014	1.477MetAsp: 1.477 ± 0.036	1.379MetGlu: 1.379 ± 0.033	0.894MetPhe: 0.894 ± 0.027	2.284MetGly: 2.284 ± 0.043	0.485MetHis: 0.485 ± 0.019	1.646MetIle: 1.646 ± 0.047	1.099MetLys: 1.099 ± 0.032	2.632MetLeu: 2.632 ± 0.051	0.84MetMet: 0.84 ± 0.028	0.84MetAsn: 0.84 ± 0.027	1.533MetPro: 1.533 ± 0.035	1.045MetGln: 1.045 ± 0.029	1.938MetArg: 1.938 ± 0.042	1.906MetSer: 1.906 ± 0.043	2.083MetThr: 2.083 ± 0.04	1.961MetVal: 1.961 ± 0.042	0.27MetTrp: 0.27 ± 0.014	0.389MetTyr: 0.389 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.241AsnAla: 3.241 ± 0.056	0.295AsnCys: 0.295 ± 0.017	1.548AsnAsp: 1.548 ± 0.037	1.311AsnGlu: 1.311 ± 0.035	0.991AsnPhe: 0.991 ± 0.031	2.587AsnGly: 2.587 ± 0.053	0.537AsnHis: 0.537 ± 0.023	1.466AsnIle: 1.466 ± 0.036	0.704AsnLys: 0.704 ± 0.026	2.498AsnLeu: 2.498 ± 0.048	0.712AsnMet: 0.712 ± 0.024	0.682AsnAsn: 0.682 ± 0.025	1.929AsnPro: 1.929 ± 0.042	0.767AsnGln: 0.767 ± 0.024	1.867AsnArg: 1.867 ± 0.042	1.235AsnSer: 1.235 ± 0.037	1.487AsnThr: 1.487 ± 0.036	1.879AsnVal: 1.879 ± 0.042	0.457AsnTrp: 0.457 ± 0.024	0.653AsnTyr: 0.653 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	5.003ProAla: 5.003 ± 0.068	0.351ProCys: 0.351 ± 0.019	4.091ProAsp: 4.091 ± 0.073	4.196ProGlu: 4.196 ± 0.057	2.088ProPhe: 2.088 ± 0.043	4.214ProGly: 4.214 ± 0.061	1.068ProHis: 1.068 ± 0.028	2.421ProIle: 2.421 ± 0.044	1.911ProLys: 1.911 ± 0.046	4.541ProLeu: 4.541 ± 0.072	1.325ProMet: 1.325 ± 0.03	1.471ProAsn: 1.471 ± 0.036	2.107ProPro: 2.107 ± 0.054	1.56ProGln: 1.56 ± 0.033	2.601ProArg: 2.601 ± 0.052	2.685ProSer: 2.685 ± 0.048	2.481ProThr: 2.481 ± 0.039	4.106ProVal: 4.106 ± 0.065	0.681ProTrp: 0.681 ± 0.022	1.182ProTyr: 1.182 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.778GlnAla: 3.778 ± 0.072	0.211GlnCys: 0.211 ± 0.015	1.869GlnAsp: 1.869 ± 0.037	1.636GlnGlu: 1.636 ± 0.041	1.148GlnPhe: 1.148 ± 0.029	2.497GlnGly: 2.497 ± 0.047	0.617GlnHis: 0.617 ± 0.024	2.066GlnIle: 2.066 ± 0.044	1.1GlnLys: 1.1 ± 0.03	2.848GlnLeu: 2.848 ± 0.054	1.05GlnMet: 1.05 ± 0.03	0.99GlnAsn: 0.99 ± 0.029	1.64GlnPro: 1.64 ± 0.043	1.045GlnGln: 1.045 ± 0.031	2.036GlnArg: 2.036 ± 0.047	1.952GlnSer: 1.952 ± 0.04	1.981GlnThr: 1.981 ± 0.042	2.349GlnVal: 2.349 ± 0.046	0.421GlnTrp: 0.421 ± 0.021	0.642GlnTyr: 0.642 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.228ArgAla: 7.228 ± 0.089	0.47ArgCys: 0.47 ± 0.019	4.244ArgAsp: 4.244 ± 0.06	3.813ArgGlu: 3.813 ± 0.067	2.743ArgPhe: 2.743 ± 0.047	4.389ArgGly: 4.389 ± 0.065	1.487ArgHis: 1.487 ± 0.034	3.812ArgIle: 3.812 ± 0.067	2.443ArgLys: 2.443 ± 0.055	6.683ArgLeu: 6.683 ± 0.082	1.942ArgMet: 1.942 ± 0.036	1.897ArgAsn: 1.897 ± 0.043	3.043ArgPro: 3.043 ± 0.058	2.214ArgGln: 2.214 ± 0.042	4.56ArgArg: 4.56 ± 0.07	3.36ArgSer: 3.36 ± 0.055	3.106ArgThr: 3.106 ± 0.059	4.799ArgVal: 4.799 ± 0.076	0.912ArgTrp: 0.912 ± 0.033	1.581ArgTyr: 1.581 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.885SerAla: 5.885 ± 0.078	0.465SerCys: 0.465 ± 0.024	3.602SerAsp: 3.602 ± 0.056	3.356SerGlu: 3.356 ± 0.051	2.336SerPhe: 2.336 ± 0.046	5.413SerGly: 5.413 ± 0.075	1.096SerHis: 1.096 ± 0.028	2.657SerIle: 2.657 ± 0.051	1.702SerLys: 1.702 ± 0.042	5.235SerLeu: 5.235 ± 0.071	1.461SerMet: 1.461 ± 0.04	1.464SerAsn: 1.464 ± 0.038	2.452SerPro: 2.452 ± 0.048	1.607SerGln: 1.607 ± 0.036	3.27SerArg: 3.27 ± 0.059	2.673SerSer: 2.673 ± 0.053	2.61SerThr: 2.61 ± 0.047	4.107SerVal: 4.107 ± 0.064	0.722SerTrp: 0.722 ± 0.024	1.369SerTyr: 1.369 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.976ThrAla: 5.976 ± 0.074	0.517ThrCys: 0.517 ± 0.022	3.311ThrAsp: 3.311 ± 0.049	3.271ThrGlu: 3.271 ± 0.052	2.082ThrPhe: 2.082 ± 0.044	5.456ThrGly: 5.456 ± 0.066	1.186ThrHis: 1.186 ± 0.037	2.853ThrIle: 2.853 ± 0.043	1.64ThrLys: 1.64 ± 0.04	6.171ThrLeu: 6.171 ± 0.071	1.319ThrMet: 1.319 ± 0.033	1.379ThrAsn: 1.379 ± 0.035	3.45ThrPro: 3.45 ± 0.057	1.718ThrGln: 1.718 ± 0.038	3.535ThrArg: 3.535 ± 0.056	2.768ThrSer: 2.768 ± 0.056	2.831ThrThr: 2.831 ± 0.052	4.334ThrVal: 4.334 ± 0.056	0.714ThrTrp: 0.714 ± 0.025	1.331ThrTyr: 1.331 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	8.497ValAla: 8.497 ± 0.097	0.699ValCys: 0.699 ± 0.023	4.175ValAsp: 4.175 ± 0.069	4.399ValGlu: 4.399 ± 0.065	3.084ValPhe: 3.084 ± 0.052	5.513ValGly: 5.513 ± 0.077	1.409ValHis: 1.409 ± 0.031	4.449ValIle: 4.449 ± 0.058	2.209ValLys: 2.209 ± 0.044	7.566ValLeu: 7.566 ± 0.084	2.212ValMet: 2.212 ± 0.047	2.006ValAsn: 2.006 ± 0.044	3.683ValPro: 3.683 ± 0.057	2.215ValGln: 2.215 ± 0.051	4.196ValArg: 4.196 ± 0.063	4.507ValSer: 4.507 ± 0.06	4.702ValThr: 4.702 ± 0.063	5.648ValVal: 5.648 ± 0.089	1.014ValTrp: 1.014 ± 0.032	1.512ValTyr: 1.512 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.375TrpAla: 1.375 ± 0.034	0.142TrpCys: 0.142 ± 0.011	0.855TrpAsp: 0.855 ± 0.027	0.679TrpGlu: 0.679 ± 0.024	0.621TrpPhe: 0.621 ± 0.024	1.02TrpGly: 1.02 ± 0.032	0.339TrpHis: 0.339 ± 0.021	0.729TrpIle: 0.729 ± 0.026	0.487TrpLys: 0.487 ± 0.02	1.648TrpLeu: 1.648 ± 0.043	0.444TrpMet: 0.444 ± 0.02	0.472TrpAsn: 0.472 ± 0.018	0.663TrpPro: 0.663 ± 0.028	0.578TrpGln: 0.578 ± 0.023	1.039TrpArg: 1.039 ± 0.029	0.821TrpSer: 0.821 ± 0.027	0.829TrpThr: 0.829 ± 0.029	0.979TrpVal: 0.979 ± 0.029	0.211TrpTrp: 0.211 ± 0.013	0.299TrpTyr: 0.299 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.479TyrAla: 2.479 ± 0.049	0.259TyrCys: 0.259 ± 0.015	1.674TyrAsp: 1.674 ± 0.036	1.333TyrGlu: 1.333 ± 0.037	0.984TyrPhe: 0.984 ± 0.027	2.112TyrGly: 2.112 ± 0.046	0.549TyrHis: 0.549 ± 0.022	0.986TyrIle: 0.986 ± 0.026	0.643TyrLys: 0.643 ± 0.023	2.381TyrLeu: 2.381 ± 0.044	0.512TyrMet: 0.512 ± 0.022	0.61TyrAsn: 0.61 ± 0.026	1.109TyrPro: 1.109 ± 0.031	0.729TyrGln: 0.729 ± 0.026	1.559TyrArg: 1.559 ± 0.036	1.24TyrSer: 1.24 ± 0.034	1.193TyrThr: 1.193 ± 0.039	1.627TyrVal: 1.627 ± 0.04	0.378TyrTrp: 0.378 ± 0.019	0.628TyrTyr: 0.628 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3878 proteins (1194701 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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