Amino acid dipepetide frequency for Maritalea myrionectae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.232AlaAla: 12.232 ± 0.157	0.791AlaCys: 0.791 ± 0.032	6.288AlaAsp: 6.288 ± 0.08	6.817AlaGlu: 6.817 ± 0.112	4.268AlaPhe: 4.268 ± 0.07	7.992AlaGly: 7.992 ± 0.089	2.37AlaHis: 2.37 ± 0.043	6.583AlaIle: 6.583 ± 0.096	5.191AlaLys: 5.191 ± 0.083	11.566AlaLeu: 11.566 ± 0.134	3.229AlaMet: 3.229 ± 0.053	3.652AlaAsn: 3.652 ± 0.059	4.44AlaPro: 4.44 ± 0.068	4.793AlaGln: 4.793 ± 0.064	5.7AlaArg: 5.7 ± 0.085	5.365AlaSer: 5.365 ± 0.078	5.379AlaThr: 5.379 ± 0.075	6.714AlaVal: 6.714 ± 0.081	1.084AlaTrp: 1.084 ± 0.037	2.493AlaTyr: 2.493 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.963CysAla: 0.963 ± 0.031	0.109CysCys: 0.109 ± 0.01	0.583CysAsp: 0.583 ± 0.028	0.478CysGlu: 0.478 ± 0.021	0.399CysPhe: 0.399 ± 0.02	0.842CysGly: 0.842 ± 0.03	0.267CysHis: 0.267 ± 0.015	0.39CysIle: 0.39 ± 0.019	0.273CysLys: 0.273 ± 0.018	0.785CysLeu: 0.785 ± 0.025	0.176CysMet: 0.176 ± 0.013	0.254CysAsn: 0.254 ± 0.017	0.407CysPro: 0.407 ± 0.019	0.287CysGln: 0.287 ± 0.016	0.453CysArg: 0.453 ± 0.022	0.432CysSer: 0.432 ± 0.022	0.449CysThr: 0.449 ± 0.02	0.567CysVal: 0.567 ± 0.021	0.109CysTrp: 0.109 ± 0.01	0.219CysTyr: 0.219 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.227AspAla: 6.227 ± 0.088	0.491AspCys: 0.491 ± 0.025	3.678AspAsp: 3.678 ± 0.113	4.479AspGlu: 4.479 ± 0.077	2.519AspPhe: 2.519 ± 0.056	5.013AspGly: 5.013 ± 0.147	1.499AspHis: 1.499 ± 0.038	3.729AspIle: 3.729 ± 0.068	2.614AspLys: 2.614 ± 0.052	6.14AspLeu: 6.14 ± 0.094	1.689AspMet: 1.689 ± 0.045	1.882AspAsn: 1.882 ± 0.046	2.985AspPro: 2.985 ± 0.045	2.81AspGln: 2.81 ± 0.058	3.394AspArg: 3.394 ± 0.062	2.329AspSer: 2.329 ± 0.058	2.329AspThr: 2.329 ± 0.066	4.362AspVal: 4.362 ± 0.073	0.993AspTrp: 0.993 ± 0.028	1.644AspTyr: 1.644 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	6.686GluAla: 6.686 ± 0.099	0.396GluCys: 0.396 ± 0.019	3.249GluAsp: 3.249 ± 0.078	3.902GluGlu: 3.902 ± 0.072	2.353GluPhe: 2.353 ± 0.052	4.307GluGly: 4.307 ± 0.065	1.34GluHis: 1.34 ± 0.036	4.357GluIle: 4.357 ± 0.062	3.46GluLys: 3.46 ± 0.073	6.229GluLeu: 6.229 ± 0.092	2.043GluMet: 2.043 ± 0.041	2.51GluAsn: 2.51 ± 0.044	2.397GluPro: 2.397 ± 0.041	2.805GluGln: 2.805 ± 0.061	4.014GluArg: 4.014 ± 0.074	2.546GluSer: 2.546 ± 0.051	3.571GluThr: 3.571 ± 0.061	4.203GluVal: 4.203 ± 0.064	0.765GluTrp: 0.765 ± 0.027	1.257GluTyr: 1.257 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	4.774PheAla: 4.774 ± 0.079	0.496PheCys: 0.496 ± 0.021	3.199PheAsp: 3.199 ± 0.061	2.885PheGlu: 2.885 ± 0.055	1.854PhePhe: 1.854 ± 0.051	3.951PheGly: 3.951 ± 0.07	0.733PheHis: 0.733 ± 0.028	2.225PheIle: 2.225 ± 0.047	1.623PheLys: 1.623 ± 0.038	3.777PheLeu: 3.777 ± 0.069	1.073PheMet: 1.073 ± 0.035	1.476PheAsn: 1.476 ± 0.039	1.504PhePro: 1.504 ± 0.038	1.179PheGln: 1.179 ± 0.033	1.74PheArg: 1.74 ± 0.04	2.678PheSer: 2.678 ± 0.059	2.177PheThr: 2.177 ± 0.049	3.27PheVal: 3.27 ± 0.052	0.629PheTrp: 0.629 ± 0.026	1.161PheTyr: 1.161 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	7.908GlyAla: 7.908 ± 0.099	0.774GlyCys: 0.774 ± 0.027	4.588GlyAsp: 4.588 ± 0.14	5.042GlyGlu: 5.042 ± 0.071	3.747GlyPhe: 3.747 ± 0.069	6.15GlyGly: 6.15 ± 0.115	1.809GlyHis: 1.809 ± 0.042	4.499GlyIle: 4.499 ± 0.084	3.624GlyLys: 3.624 ± 0.071	7.98GlyLeu: 7.98 ± 0.102	2.271GlyMet: 2.271 ± 0.049	2.446GlyAsn: 2.446 ± 0.058	2.796GlyPro: 2.796 ± 0.049	3.096GlyGln: 3.096 ± 0.048	4.307GlyArg: 4.307 ± 0.067	3.829GlySer: 3.829 ± 0.077	4.16GlyThr: 4.16 ± 0.078	5.742GlyVal: 5.742 ± 0.085	1.124GlyTrp: 1.124 ± 0.038	2.36GlyTyr: 2.36 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.988HisAla: 1.988 ± 0.051	0.217HisCys: 0.217 ± 0.014	1.314HisAsp: 1.314 ± 0.034	1.246HisGlu: 1.246 ± 0.027	1.1HisPhe: 1.1 ± 0.033	1.621HisGly: 1.621 ± 0.041	0.663HisHis: 0.663 ± 0.028	1.325HisIle: 1.325 ± 0.038	0.891HisLys: 0.891 ± 0.03	2.226HisLeu: 2.226 ± 0.046	0.639HisMet: 0.639 ± 0.023	0.713HisAsn: 0.713 ± 0.028	1.178HisPro: 1.178 ± 0.039	0.831HisGln: 0.831 ± 0.028	1.133HisArg: 1.133 ± 0.034	1.021HisSer: 1.021 ± 0.029	0.892HisThr: 0.892 ± 0.027	1.458HisVal: 1.458 ± 0.037	0.314HisTrp: 0.314 ± 0.02	0.687HisTyr: 0.687 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	7.071IleAla: 7.071 ± 0.103	0.654IleCys: 0.654 ± 0.024	4.075IleAsp: 4.075 ± 0.066	4.49IleGlu: 4.49 ± 0.071	2.521IlePhe: 2.521 ± 0.062	5.203IleGly: 5.203 ± 0.084	0.946IleHis: 0.946 ± 0.032	3.292IleIle: 3.292 ± 0.067	2.554IleLys: 2.554 ± 0.042	5.546IleLeu: 5.546 ± 0.085	1.367IleMet: 1.367 ± 0.036	2.094IleAsn: 2.094 ± 0.044	2.204IlePro: 2.204 ± 0.049	1.563IleGln: 1.563 ± 0.035	2.593IleArg: 2.593 ± 0.051	3.913IleSer: 3.913 ± 0.069	3.127IleThr: 3.127 ± 0.058	4.692IleVal: 4.692 ± 0.069	0.779IleTrp: 0.779 ± 0.026	1.527IleTyr: 1.527 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	4.742LysAla: 4.742 ± 0.069	0.27LysCys: 0.27 ± 0.014	2.589LysAsp: 2.589 ± 0.057	2.487LysGlu: 2.487 ± 0.047	1.497LysPhe: 1.497 ± 0.038	3.26LysGly: 3.26 ± 0.075	0.894LysHis: 0.894 ± 0.036	2.771LysIle: 2.771 ± 0.057	2.363LysLys: 2.363 ± 0.058	4.404LysLeu: 4.404 ± 0.071	1.26LysMet: 1.26 ± 0.036	1.626LysAsn: 1.626 ± 0.043	2.255LysPro: 2.255 ± 0.049	1.722LysGln: 1.722 ± 0.045	2.832LysArg: 2.832 ± 0.059	2.901LysSer: 2.901 ± 0.055	2.484LysThr: 2.484 ± 0.054	2.95LysVal: 2.95 ± 0.055	0.54LysTrp: 0.54 ± 0.023	0.995LysTyr: 0.995 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	11.29LeuAla: 11.29 ± 0.104	0.889LeuCys: 0.889 ± 0.03	6.234LeuAsp: 6.234 ± 0.08	5.654LeuGlu: 5.654 ± 0.085	4.072LeuPhe: 4.072 ± 0.071	7.875LeuGly: 7.875 ± 0.099	1.809LeuHis: 1.809 ± 0.04	5.803LeuIle: 5.803 ± 0.097	4.48LeuLys: 4.48 ± 0.075	8.945LeuLeu: 8.945 ± 0.122	2.654LeuMet: 2.654 ± 0.059	3.718LeuAsn: 3.718 ± 0.063	4.794LeuPro: 4.794 ± 0.075	3.03LeuGln: 3.03 ± 0.055	5.184LeuArg: 5.184 ± 0.076	6.706LeuSer: 6.706 ± 0.076	5.405LeuThr: 5.405 ± 0.069	7.147LeuVal: 7.147 ± 0.083	0.998LeuTrp: 0.998 ± 0.035	2.231LeuTyr: 2.231 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.218MetAla: 3.218 ± 0.057	0.204MetCys: 0.204 ± 0.015	1.458MetAsp: 1.458 ± 0.037	1.279MetGlu: 1.279 ± 0.036	0.886MetPhe: 0.886 ± 0.032	2.163MetGly: 2.163 ± 0.048	0.5MetHis: 0.5 ± 0.022	1.695MetIle: 1.695 ± 0.047	1.124MetLys: 1.124 ± 0.034	2.665MetLeu: 2.665 ± 0.054	0.799MetMet: 0.799 ± 0.034	0.947MetAsn: 0.947 ± 0.032	1.5MetPro: 1.5 ± 0.042	1.029MetGln: 1.029 ± 0.028	1.787MetArg: 1.787 ± 0.04	2.025MetSer: 2.025 ± 0.049	1.796MetThr: 1.796 ± 0.046	2.034MetVal: 2.034 ± 0.042	0.243MetTrp: 0.243 ± 0.016	0.347MetTyr: 0.347 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.841AsnAla: 3.841 ± 0.071	0.357AsnCys: 0.357 ± 0.024	2.049AsnAsp: 2.049 ± 0.071	1.968AsnGlu: 1.968 ± 0.043	1.402AsnPhe: 1.402 ± 0.032	2.897AsnGly: 2.897 ± 0.061	0.721AsnHis: 0.721 ± 0.024	2.215AsnIle: 2.215 ± 0.045	1.442AsnLys: 1.442 ± 0.036	3.413AsnLeu: 3.413 ± 0.055	0.98AsnMet: 0.98 ± 0.037	1.14AsnAsn: 1.14 ± 0.032	1.956AsnPro: 1.956 ± 0.037	1.331AsnGln: 1.331 ± 0.038	1.846AsnArg: 1.846 ± 0.044	1.926AsnSer: 1.926 ± 0.048	1.529AsnThr: 1.529 ± 0.033	2.522AsnVal: 2.522 ± 0.053	0.598AsnTrp: 0.598 ± 0.024	0.978AsnTyr: 0.978 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	4.102ProAla: 4.102 ± 0.061	0.279ProCys: 0.279 ± 0.014	3.178ProAsp: 3.178 ± 0.063	3.449ProGlu: 3.449 ± 0.06	2.075ProPhe: 2.075 ± 0.049	3.17ProGly: 3.17 ± 0.06	1.126ProHis: 1.126 ± 0.036	2.743ProIle: 2.743 ± 0.049	2.222ProLys: 2.222 ± 0.047	4.136ProLeu: 4.136 ± 0.062	1.108ProMet: 1.108 ± 0.035	1.838ProAsn: 1.838 ± 0.044	1.686ProPro: 1.686 ± 0.049	1.83ProGln: 1.83 ± 0.043	1.912ProArg: 1.912 ± 0.041	2.579ProSer: 2.579 ± 0.042	2.479ProThr: 2.479 ± 0.049	3.171ProVal: 3.171 ± 0.057	0.531ProTrp: 0.531 ± 0.024	1.169ProTyr: 1.169 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.752GlnAla: 3.752 ± 0.067	0.261GlnCys: 0.261 ± 0.016	1.963GlnAsp: 1.963 ± 0.051	1.938GlnGlu: 1.938 ± 0.041	1.716GlnPhe: 1.716 ± 0.041	2.496GlnGly: 2.496 ± 0.05	0.885GlnHis: 0.885 ± 0.028	2.554GlnIle: 2.554 ± 0.05	1.986GlnLys: 1.986 ± 0.05	3.946GlnLeu: 3.946 ± 0.064	1.244GlnMet: 1.244 ± 0.038	1.564GlnAsn: 1.564 ± 0.039	1.649GlnPro: 1.649 ± 0.035	1.662GlnGln: 1.662 ± 0.045	2.273GlnArg: 2.273 ± 0.05	2.529GlnSer: 2.529 ± 0.056	2.094GlnThr: 2.094 ± 0.042	2.48GlnVal: 2.48 ± 0.047	0.419GlnTrp: 0.419 ± 0.019	0.851GlnTyr: 0.851 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	5.654ArgAla: 5.654 ± 0.078	0.403ArgCys: 0.403 ± 0.021	3.372ArgAsp: 3.372 ± 0.054	3.488ArgGlu: 3.488 ± 0.058	2.457ArgPhe: 2.457 ± 0.05	3.479ArgGly: 3.479 ± 0.061	1.313ArgHis: 1.313 ± 0.037	3.151ArgIle: 3.151 ± 0.058	2.405ArgLys: 2.405 ± 0.055	5.795ArgLeu: 5.795 ± 0.085	1.508ArgMet: 1.508 ± 0.038	1.888ArgAsn: 1.888 ± 0.043	2.326ArgPro: 2.326 ± 0.049	2.382ArgGln: 2.382 ± 0.046	3.337ArgArg: 3.337 ± 0.062	2.705ArgSer: 2.705 ± 0.051	2.769ArgThr: 2.769 ± 0.054	3.703ArgVal: 3.703 ± 0.063	0.656ArgTrp: 0.656 ± 0.029	1.412ArgTyr: 1.412 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	5.828SerAla: 5.828 ± 0.083	0.438SerCys: 0.438 ± 0.023	3.329SerAsp: 3.329 ± 0.081	3.141SerGlu: 3.141 ± 0.06	2.754SerPhe: 2.754 ± 0.053	4.955SerGly: 4.955 ± 0.092	1.135SerHis: 1.135 ± 0.036	3.487SerIle: 3.487 ± 0.055	2.403SerLys: 2.403 ± 0.052	5.47SerLeu: 5.47 ± 0.073	1.553SerMet: 1.553 ± 0.041	1.949SerAsn: 1.949 ± 0.039	2.421SerPro: 2.421 ± 0.047	2.004SerGln: 2.004 ± 0.047	2.791SerArg: 2.791 ± 0.049	3.019SerSer: 3.019 ± 0.069	2.985SerThr: 2.985 ± 0.058	3.88SerVal: 3.88 ± 0.062	0.701SerTrp: 0.701 ± 0.028	1.444SerTyr: 1.444 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	5.207ThrAla: 5.207 ± 0.082	0.425ThrCys: 0.425 ± 0.023	3.023ThrAsp: 3.023 ± 0.056	2.821ThrGlu: 2.821 ± 0.053	2.048ThrPhe: 2.048 ± 0.044	4.463ThrGly: 4.463 ± 0.065	1.172ThrHis: 1.172 ± 0.033	3.525ThrIle: 3.525 ± 0.058	2.115ThrLys: 2.115 ± 0.044	5.298ThrLeu: 5.298 ± 0.068	1.225ThrMet: 1.225 ± 0.033	1.936ThrAsn: 1.936 ± 0.039	3.12ThrPro: 3.12 ± 0.059	1.921ThrGln: 1.921 ± 0.039	2.597ThrArg: 2.597 ± 0.05	3.096ThrSer: 3.096 ± 0.065	2.812ThrThr: 2.812 ± 0.053	3.456ThrVal: 3.456 ± 0.055	0.545ThrTrp: 0.545 ± 0.026	1.395ThrTyr: 1.395 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	7.73ValAla: 7.73 ± 0.088	0.581ValCys: 0.581 ± 0.023	4.398ValAsp: 4.398 ± 0.066	4.775ValGlu: 4.775 ± 0.063	2.941ValPhe: 2.941 ± 0.061	5.472ValGly: 5.472 ± 0.081	1.371ValHis: 1.371 ± 0.039	4.026ValIle: 4.026 ± 0.06	2.796ValLys: 2.796 ± 0.059	6.654ValLeu: 6.654 ± 0.079	1.97ValMet: 1.97 ± 0.047	2.311ValAsn: 2.311 ± 0.051	3.402ValPro: 3.402 ± 0.059	2.321ValGln: 2.321 ± 0.043	3.955ValArg: 3.955 ± 0.066	4.123ValSer: 4.123 ± 0.07	3.949ValThr: 3.949 ± 0.07	5.242ValVal: 5.242 ± 0.081	0.821ValTrp: 0.821 ± 0.031	1.471ValTyr: 1.471 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.209TrpAla: 1.209 ± 0.039	0.119TrpCys: 0.119 ± 0.01	0.643TrpAsp: 0.643 ± 0.026	0.531TrpGlu: 0.531 ± 0.022	0.556TrpPhe: 0.556 ± 0.027	0.835TrpGly: 0.835 ± 0.027	0.346TrpHis: 0.346 ± 0.021	0.65TrpIle: 0.65 ± 0.028	0.373TrpLys: 0.373 ± 0.017	1.404TrpLeu: 1.404 ± 0.035	0.347TrpMet: 0.347 ± 0.019	0.411TrpAsn: 0.411 ± 0.02	0.679TrpPro: 0.679 ± 0.026	0.681TrpGln: 0.681 ± 0.025	0.871TrpArg: 0.871 ± 0.031	0.721TrpSer: 0.721 ± 0.029	0.679TrpThr: 0.679 ± 0.027	0.93TrpVal: 0.93 ± 0.026	0.196TrpTrp: 0.196 ± 0.013	0.269TrpTyr: 0.269 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.529TyrAla: 2.529 ± 0.052	0.288TyrCys: 0.288 ± 0.014	1.594TyrAsp: 1.594 ± 0.042	1.521TyrGlu: 1.521 ± 0.04	1.238TyrPhe: 1.238 ± 0.032	2.11TyrGly: 2.11 ± 0.044	0.557TyrHis: 0.557 ± 0.024	1.19TyrIle: 1.19 ± 0.035	0.902TyrLys: 0.902 ± 0.027	2.54TyrLeu: 2.54 ± 0.044	0.562TyrMet: 0.562 ± 0.023	0.758TyrAsn: 0.758 ± 0.025	1.082TyrPro: 1.082 ± 0.033	0.981TyrGln: 0.981 ± 0.034	1.482TyrArg: 1.482 ± 0.04	1.24TyrSer: 1.24 ± 0.036	1.139TyrThr: 1.139 ± 0.034	1.788TyrVal: 1.788 ± 0.04	0.407TyrTrp: 0.407 ± 0.019	0.723TyrTyr: 0.723 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3695 proteins (1120000 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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