Amino acid dipepetide frequency for Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.393AlaAla: 8.393 ± 0.059	1.143AlaCys: 1.143 ± 0.016	4.129AlaAsp: 4.129 ± 0.026	4.98AlaGlu: 4.98 ± 0.037	3.192AlaPhe: 3.192 ± 0.026	5.586AlaGly: 5.586 ± 0.035	1.683AlaHis: 1.683 ± 0.017	4.551AlaIle: 4.551 ± 0.03	4.186AlaLys: 4.186 ± 0.031	7.588AlaLeu: 7.588 ± 0.041	2.004AlaMet: 2.004 ± 0.017	2.952AlaAsn: 2.952 ± 0.021	4.6AlaPro: 4.6 ± 0.039	3.25AlaGln: 3.25 ± 0.025	4.492AlaArg: 4.492 ± 0.028	6.947AlaSer: 6.947 ± 0.037	5.219AlaThr: 5.219 ± 0.035	5.258AlaVal: 5.258 ± 0.032	1.236AlaTrp: 1.236 ± 0.014	2.193AlaTyr: 2.193 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.953CysAla: 0.953 ± 0.013	0.262CysCys: 0.262 ± 0.007	0.733CysAsp: 0.733 ± 0.013	0.649CysGlu: 0.649 ± 0.011	0.59CysPhe: 0.59 ± 0.01	0.991CysGly: 0.991 ± 0.014	0.358CysHis: 0.358 ± 0.008	0.8CysIle: 0.8 ± 0.012	0.593CysLys: 0.593 ± 0.011	1.312CysLeu: 1.312 ± 0.015	0.299CysMet: 0.299 ± 0.006	0.488CysAsn: 0.488 ± 0.009	0.685CysPro: 0.685 ± 0.013	0.509CysGln: 0.509 ± 0.008	0.771CysArg: 0.771 ± 0.011	0.972CysSer: 0.972 ± 0.014	0.747CysThr: 0.747 ± 0.012	0.844CysVal: 0.844 ± 0.013	0.237CysTrp: 0.237 ± 0.006	0.403CysTyr: 0.403 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.65AspAla: 4.65 ± 0.03	0.682AspCys: 0.682 ± 0.011	4.302AspAsp: 4.302 ± 0.039	4.5AspGlu: 4.5 ± 0.034	2.311AspPhe: 2.311 ± 0.02	4.078AspGly: 4.078 ± 0.028	1.273AspHis: 1.273 ± 0.015	3.28AspIle: 3.28 ± 0.023	2.716AspLys: 2.716 ± 0.022	5.122AspLeu: 5.122 ± 0.032	1.357AspMet: 1.357 ± 0.014	2.049AspAsn: 2.049 ± 0.018	3.29AspPro: 3.29 ± 0.025	1.964AspGln: 1.964 ± 0.02	2.957AspArg: 2.957 ± 0.025	4.101AspSer: 4.101 ± 0.029	3.048AspThr: 3.048 ± 0.023	3.693AspVal: 3.693 ± 0.027	0.977AspTrp: 0.977 ± 0.013	1.665AspTyr: 1.665 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.496GluAla: 5.496 ± 0.04	0.666GluCys: 0.666 ± 0.011	4.142GluAsp: 4.142 ± 0.034	5.186GluGlu: 5.186 ± 0.052	2.02GluPhe: 2.02 ± 0.017	3.654GluGly: 3.654 ± 0.023	1.417GluHis: 1.417 ± 0.014	3.107GluIle: 3.107 ± 0.025	3.736GluLys: 3.736 ± 0.03	5.182GluLeu: 5.182 ± 0.034	1.463GluMet: 1.463 ± 0.015	2.368GluAsn: 2.368 ± 0.022	2.908GluPro: 2.908 ± 0.031	2.412GluGln: 2.412 ± 0.022	3.667GluArg: 3.667 ± 0.027	4.27GluSer: 4.27 ± 0.027	3.76GluThr: 3.76 ± 0.032	3.609GluVal: 3.609 ± 0.026	0.938GluTrp: 0.938 ± 0.013	1.689GluTyr: 1.689 ± 0.016	0.001GluXaa: 0.001 ± 0.0
Phe	3.049PheAla: 3.049 ± 0.023	0.606PheCys: 0.606 ± 0.01	2.369PheAsp: 2.369 ± 0.018	2.217PheGlu: 2.217 ± 0.02	1.727PhePhe: 1.727 ± 0.02	2.947PheGly: 2.947 ± 0.027	0.926PheHis: 0.926 ± 0.014	2.051PheIle: 2.051 ± 0.02	1.667PheLys: 1.667 ± 0.018	3.514PheLeu: 3.514 ± 0.026	0.871PheMet: 0.871 ± 0.013	1.558PheAsn: 1.558 ± 0.014	1.928PhePro: 1.928 ± 0.019	1.446PheGln: 1.446 ± 0.016	1.91PheArg: 1.91 ± 0.019	3.008PheSer: 3.008 ± 0.022	2.248PheThr: 2.248 ± 0.018	2.435PheVal: 2.435 ± 0.022	0.701PheTrp: 0.701 ± 0.011	1.169PheTyr: 1.169 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.145GlyAla: 5.145 ± 0.029	0.958GlyCys: 0.958 ± 0.011	3.744GlyAsp: 3.744 ± 0.03	3.506GlyGlu: 3.506 ± 0.029	2.955GlyPhe: 2.955 ± 0.029	5.384GlyGly: 5.384 ± 0.045	1.711GlyHis: 1.711 ± 0.019	3.744GlyIle: 3.744 ± 0.025	3.47GlyLys: 3.47 ± 0.027	6.181GlyLeu: 6.181 ± 0.035	1.585GlyMet: 1.585 ± 0.017	2.676GlyAsn: 2.676 ± 0.024	3.295GlyPro: 3.295 ± 0.025	2.593GlyGln: 2.593 ± 0.023	3.916GlyArg: 3.916 ± 0.03	5.65GlySer: 5.65 ± 0.038	4.014GlyThr: 4.014 ± 0.034	4.285GlyVal: 4.285 ± 0.033	1.231GlyTrp: 1.231 ± 0.016	2.234GlyTyr: 2.234 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.747HisAla: 1.747 ± 0.017	0.35HisCys: 0.35 ± 0.008	1.387HisAsp: 1.387 ± 0.015	1.383HisGlu: 1.383 ± 0.015	0.934HisPhe: 0.934 ± 0.011	1.754HisGly: 1.754 ± 0.019	0.835HisHis: 0.835 ± 0.019	1.289HisIle: 1.289 ± 0.014	0.984HisLys: 0.984 ± 0.015	2.238HisLeu: 2.238 ± 0.02	0.529HisMet: 0.529 ± 0.009	0.873HisAsn: 0.873 ± 0.011	1.533HisPro: 1.533 ± 0.016	0.986HisGln: 0.986 ± 0.013	1.465HisArg: 1.465 ± 0.016	1.736HisSer: 1.736 ± 0.02	1.198HisThr: 1.198 ± 0.014	1.447HisVal: 1.447 ± 0.015	0.37HisTrp: 0.37 ± 0.006	0.72HisTyr: 0.72 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.372IleAla: 4.372 ± 0.026	0.828IleCys: 0.828 ± 0.01	3.069IleAsp: 3.069 ± 0.024	3.092IleGlu: 3.092 ± 0.024	2.122IlePhe: 2.122 ± 0.019	3.438IleGly: 3.438 ± 0.029	1.266IleHis: 1.266 ± 0.015	2.827IleIle: 2.827 ± 0.027	2.432IleLys: 2.432 ± 0.019	4.752IleLeu: 4.752 ± 0.033	1.121IleMet: 1.121 ± 0.012	2.0IleAsn: 2.0 ± 0.017	3.089IlePro: 3.089 ± 0.025	1.999IleGln: 1.999 ± 0.018	2.837IleArg: 2.837 ± 0.023	3.992IleSer: 3.992 ± 0.024	3.082IleThr: 3.082 ± 0.032	3.327IleVal: 3.327 ± 0.026	0.827IleTrp: 0.827 ± 0.011	1.509IleTyr: 1.509 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.43LysAla: 4.43 ± 0.033	0.594LysCys: 0.594 ± 0.014	3.115LysAsp: 3.115 ± 0.027	3.408LysGlu: 3.408 ± 0.033	1.566LysPhe: 1.566 ± 0.017	3.132LysGly: 3.132 ± 0.023	1.2LysHis: 1.2 ± 0.015	2.391LysIle: 2.391 ± 0.017	3.408LysLys: 3.408 ± 0.038	4.257LysLeu: 4.257 ± 0.032	1.038LysMet: 1.038 ± 0.012	1.926LysAsn: 1.926 ± 0.02	2.926LysPro: 2.926 ± 0.031	1.878LysGln: 1.878 ± 0.016	3.281LysArg: 3.281 ± 0.026	3.578LysSer: 3.578 ± 0.028	3.127LysThr: 3.127 ± 0.023	2.98LysVal: 2.98 ± 0.023	0.761LysTrp: 0.761 ± 0.011	1.441LysTyr: 1.441 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.7LeuAla: 7.7 ± 0.039	1.256LeuCys: 1.256 ± 0.014	5.229LeuAsp: 5.229 ± 0.038	5.533LeuGlu: 5.533 ± 0.036	3.402LeuPhe: 3.402 ± 0.027	5.976LeuGly: 5.976 ± 0.03	2.148LeuHis: 2.148 ± 0.02	4.247LeuIle: 4.247 ± 0.029	4.337LeuLys: 4.337 ± 0.028	8.09LeuLeu: 8.09 ± 0.053	1.888LeuMet: 1.888 ± 0.018	3.226LeuAsn: 3.226 ± 0.023	5.233LeuPro: 5.233 ± 0.029	3.725LeuGln: 3.725 ± 0.027	5.388LeuArg: 5.388 ± 0.034	7.087LeuSer: 7.087 ± 0.04	4.862LeuThr: 4.862 ± 0.026	5.495LeuVal: 5.495 ± 0.031	1.29LeuTrp: 1.29 ± 0.016	2.395LeuTyr: 2.395 ± 0.02	0.001LeuXaa: 0.001 ± 0.0
Met	2.319MetAla: 2.319 ± 0.018	0.263MetCys: 0.263 ± 0.006	1.261MetAsp: 1.261 ± 0.014	1.276MetGlu: 1.276 ± 0.015	0.806MetPhe: 0.806 ± 0.012	1.514MetGly: 1.514 ± 0.015	0.495MetHis: 0.495 ± 0.008	1.111MetIle: 1.111 ± 0.015	1.081MetLys: 1.081 ± 0.014	1.887MetLeu: 1.887 ± 0.018	0.629MetMet: 0.629 ± 0.01	0.856MetAsn: 0.856 ± 0.013	1.326MetPro: 1.326 ± 0.016	0.844MetGln: 0.844 ± 0.011	1.232MetArg: 1.232 ± 0.015	2.0MetSer: 2.0 ± 0.017	1.365MetThr: 1.365 ± 0.014	1.346MetVal: 1.346 ± 0.014	0.276MetTrp: 0.276 ± 0.006	0.541MetTyr: 0.541 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.092AsnAla: 3.092 ± 0.024	0.501AsnCys: 0.501 ± 0.009	2.095AsnAsp: 2.095 ± 0.019	2.133AsnGlu: 2.133 ± 0.02	1.438AsnPhe: 1.438 ± 0.015	3.04AsnGly: 3.04 ± 0.026	0.882AsnHis: 0.882 ± 0.013	2.173AsnIle: 2.173 ± 0.019	1.79AsnLys: 1.79 ± 0.018	3.348AsnLeu: 3.348 ± 0.024	0.941AsnMet: 0.941 ± 0.013	1.624AsnAsn: 1.624 ± 0.017	2.414AsnPro: 2.414 ± 0.023	1.389AsnGln: 1.389 ± 0.017	1.926AsnArg: 1.926 ± 0.019	2.802AsnSer: 2.802 ± 0.023	2.288AsnThr: 2.288 ± 0.02	2.329AsnVal: 2.329 ± 0.021	0.645AsnTrp: 0.645 ± 0.01	1.109AsnTyr: 1.109 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.769ProAla: 4.769 ± 0.034	0.562ProCys: 0.562 ± 0.01	3.274ProAsp: 3.274 ± 0.024	4.006ProGlu: 4.006 ± 0.029	2.083ProPhe: 2.083 ± 0.02	3.951ProGly: 3.951 ± 0.041	1.252ProHis: 1.252 ± 0.014	2.578ProIle: 2.578 ± 0.019	2.825ProLys: 2.825 ± 0.027	4.53ProLeu: 4.53 ± 0.028	1.123ProMet: 1.123 ± 0.012	2.196ProAsn: 2.196 ± 0.021	4.469ProPro: 4.469 ± 0.057	2.424ProGln: 2.424 ± 0.027	3.202ProArg: 3.202 ± 0.03	5.456ProSer: 5.456 ± 0.041	3.771ProThr: 3.771 ± 0.034	3.56ProVal: 3.56 ± 0.027	0.812ProTrp: 0.812 ± 0.011	1.525ProTyr: 1.525 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.449GlnAla: 3.449 ± 0.025	0.467GlnCys: 0.467 ± 0.009	2.254GlnAsp: 2.254 ± 0.021	2.421GlnGlu: 2.421 ± 0.021	1.286GlnPhe: 1.286 ± 0.014	2.517GlnGly: 2.517 ± 0.023	1.043GlnHis: 1.043 ± 0.014	1.885GlnIle: 1.885 ± 0.018	1.971GlnLys: 1.971 ± 0.016	3.374GlnLeu: 3.374 ± 0.025	0.894GlnMet: 0.894 ± 0.013	1.589GlnAsn: 1.589 ± 0.017	2.525GlnPro: 2.525 ± 0.03	2.259GlnGln: 2.259 ± 0.037	2.476GlnArg: 2.476 ± 0.022	2.968GlnSer: 2.968 ± 0.025	2.292GlnThr: 2.292 ± 0.022	2.26GlnVal: 2.26 ± 0.018	0.618GlnTrp: 0.618 ± 0.01	1.162GlnTyr: 1.162 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.269ArgAla: 4.269 ± 0.026	0.736ArgCys: 0.736 ± 0.012	3.361ArgAsp: 3.361 ± 0.023	3.551ArgGlu: 3.551 ± 0.03	2.105ArgPhe: 2.105 ± 0.017	3.522ArgGly: 3.522 ± 0.028	1.516ArgHis: 1.516 ± 0.017	2.879ArgIle: 2.879 ± 0.023	3.272ArgLys: 3.272 ± 0.026	5.271ArgLeu: 5.271 ± 0.033	1.279ArgMet: 1.279 ± 0.014	2.219ArgAsn: 2.219 ± 0.018	3.271ArgPro: 3.271 ± 0.028	2.484ArgGln: 2.484 ± 0.021	4.646ArgArg: 4.646 ± 0.036	4.391ArgSer: 4.391 ± 0.037	3.081ArgThr: 3.081 ± 0.023	3.254ArgVal: 3.254 ± 0.027	0.956ArgTrp: 0.956 ± 0.011	1.686ArgTyr: 1.686 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.143SerAla: 6.143 ± 0.036	0.949SerCys: 0.949 ± 0.013	4.271SerAsp: 4.271 ± 0.029	4.169SerGlu: 4.169 ± 0.029	3.089SerPhe: 3.089 ± 0.026	5.42SerGly: 5.42 ± 0.033	1.921SerHis: 1.921 ± 0.018	4.171SerIle: 4.171 ± 0.025	3.833SerLys: 3.833 ± 0.022	7.04SerLeu: 7.04 ± 0.043	1.769SerMet: 1.769 ± 0.017	2.998SerAsn: 2.998 ± 0.023	5.057SerPro: 5.057 ± 0.04	3.271SerGln: 3.271 ± 0.028	4.707SerArg: 4.707 ± 0.032	7.964SerSer: 7.964 ± 0.058	5.261SerThr: 5.261 ± 0.04	4.499SerVal: 4.499 ± 0.029	1.241SerTrp: 1.241 ± 0.013	2.147SerTyr: 2.147 ± 0.018	0.001SerXaa: 0.001 ± 0.0
Thr	5.068ThrAla: 5.068 ± 0.032	0.834ThrCys: 0.834 ± 0.012	2.914ThrAsp: 2.914 ± 0.023	3.331ThrGlu: 3.331 ± 0.028	2.3ThrPhe: 2.3 ± 0.019	4.21ThrGly: 4.21 ± 0.033	1.267ThrHis: 1.267 ± 0.013	3.34ThrIle: 3.34 ± 0.036	2.902ThrLys: 2.902 ± 0.023	5.16ThrLeu: 5.16 ± 0.026	1.219ThrMet: 1.219 ± 0.013	2.197ThrAsn: 2.197 ± 0.022	4.107ThrPro: 4.107 ± 0.034	2.163ThrGln: 2.163 ± 0.021	3.071ThrArg: 3.071 ± 0.024	5.186ThrSer: 5.186 ± 0.043	4.341ThrThr: 4.341 ± 0.058	3.817ThrVal: 3.817 ± 0.041	0.953ThrTrp: 0.953 ± 0.011	1.692ThrTyr: 1.692 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.164ValAla: 5.164 ± 0.032	0.868ValCys: 0.868 ± 0.013	3.698ValAsp: 3.698 ± 0.025	3.853ValGlu: 3.853 ± 0.023	2.571ValPhe: 2.571 ± 0.022	3.957ValGly: 3.957 ± 0.031	1.368ValHis: 1.368 ± 0.016	3.217ValIle: 3.217 ± 0.025	3.088ValLys: 3.088 ± 0.023	5.527ValLeu: 5.527 ± 0.032	1.371ValMet: 1.371 ± 0.015	2.292ValAsn: 2.292 ± 0.018	3.535ValPro: 3.535 ± 0.026	2.365ValGln: 2.365 ± 0.022	3.191ValArg: 3.191 ± 0.022	4.613ValSer: 4.613 ± 0.025	3.708ValThr: 3.708 ± 0.042	4.27ValVal: 4.27 ± 0.031	0.904ValTrp: 0.904 ± 0.013	1.79ValTyr: 1.79 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.217TrpAla: 1.217 ± 0.014	0.218TrpCys: 0.218 ± 0.006	0.95TrpAsp: 0.95 ± 0.013	0.902TrpGlu: 0.902 ± 0.011	0.622TrpPhe: 0.622 ± 0.01	1.034TrpGly: 1.034 ± 0.014	0.391TrpHis: 0.391 ± 0.008	0.878TrpIle: 0.878 ± 0.013	0.9TrpLys: 0.9 ± 0.013	1.461TrpLeu: 1.461 ± 0.016	0.397TrpMet: 0.397 ± 0.009	0.685TrpAsn: 0.685 ± 0.01	0.679TrpPro: 0.679 ± 0.011	0.611TrpGln: 0.611 ± 0.009	0.958TrpArg: 0.958 ± 0.012	1.142TrpSer: 1.142 ± 0.015	1.003TrpThr: 1.003 ± 0.013	0.954TrpVal: 0.954 ± 0.012	0.305TrpTrp: 0.305 ± 0.008	0.485TrpTyr: 0.485 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.154TyrAla: 2.154 ± 0.02	0.453TyrCys: 0.453 ± 0.009	1.719TyrAsp: 1.719 ± 0.017	1.594TyrGlu: 1.594 ± 0.015	1.226TyrPhe: 1.226 ± 0.016	2.171TyrGly: 2.171 ± 0.022	0.802TyrHis: 0.802 ± 0.011	1.463TyrIle: 1.463 ± 0.017	1.245TyrLys: 1.245 ± 0.014	2.673TyrLeu: 2.673 ± 0.023	0.65TyrMet: 0.65 ± 0.01	1.189TyrAsn: 1.189 ± 0.015	1.501TyrPro: 1.501 ± 0.015	1.138TyrGln: 1.138 ± 0.015	1.659TyrArg: 1.659 ± 0.015	2.057TyrSer: 2.057 ± 0.02	1.657TyrThr: 1.657 ± 0.018	1.687TyrVal: 1.687 ± 0.016	0.515TyrTrp: 0.515 ± 0.009	0.972TyrTyr: 0.972 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.329XaaXaa: 0.329 ± 0.17

Statistics based on 15355 proteins (6888665 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---