Amino acid dipepetide frequency for Prevotella sp. oral taxon 299 str. F0039

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.23AlaAla: 4.23 ± 0.103
0.828AlaCys: 0.828 ± 0.036
3.303AlaAsp: 3.303 ± 0.076
4.053AlaGlu: 4.053 ± 0.086
3.301AlaPhe: 3.301 ± 0.075
3.925AlaGly: 3.925 ± 0.083
1.269AlaHis: 1.269 ± 0.04
5.081AlaIle: 5.081 ± 0.088
4.742AlaLys: 4.742 ± 0.094
6.92AlaLeu: 6.92 ± 0.107
1.787AlaMet: 1.787 ± 0.063
3.661AlaAsn: 3.661 ± 0.079
2.121AlaPro: 2.121 ± 0.062
3.158AlaGln: 3.158 ± 0.085
2.652AlaArg: 2.652 ± 0.063
4.378AlaSer: 4.378 ± 0.081
3.895AlaThr: 3.895 ± 0.085
4.111AlaVal: 4.111 ± 0.08
0.678AlaTrp: 0.678 ± 0.033
2.701AlaTyr: 2.701 ± 0.064
0.0AlaXaa: 0.0 ± 0.0
Cys
0.744CysAla: 0.744 ± 0.036
0.165CysCys: 0.165 ± 0.02
0.645CysAsp: 0.645 ± 0.028
0.547CysGlu: 0.547 ± 0.031
0.68CysPhe: 0.68 ± 0.032
0.888CysGly: 0.888 ± 0.037
0.283CysHis: 0.283 ± 0.022
0.854CysIle: 0.854 ± 0.031
0.757CysLys: 0.757 ± 0.035
1.026CysLeu: 1.026 ± 0.033
0.24CysMet: 0.24 ± 0.018
0.693CysAsn: 0.693 ± 0.032
0.46CysPro: 0.46 ± 0.029
0.273CysGln: 0.273 ± 0.019
0.472CysArg: 0.472 ± 0.028
0.753CysSer: 0.753 ± 0.035
0.622CysThr: 0.622 ± 0.033
0.787CysVal: 0.787 ± 0.038
0.151CysTrp: 0.151 ± 0.014
0.482CysTyr: 0.482 ± 0.025
0.0CysXaa: 0.0 ± 0.0
Asp
3.625AspAla: 3.625 ± 0.069
0.601AspCys: 0.601 ± 0.029
2.382AspAsp: 2.382 ± 0.061
3.557AspGlu: 3.557 ± 0.08
2.719AspPhe: 2.719 ± 0.069
3.391AspGly: 3.391 ± 0.085
0.817AspHis: 0.817 ± 0.039
4.519AspIle: 4.519 ± 0.083
4.182AspLys: 4.182 ± 0.084
4.556AspLeu: 4.556 ± 0.075
1.365AspMet: 1.365 ± 0.043
3.328AspAsn: 3.328 ± 0.071
1.608AspPro: 1.608 ± 0.053
1.166AspGln: 1.166 ± 0.041
1.979AspArg: 1.979 ± 0.055
3.203AspSer: 3.203 ± 0.08
2.649AspThr: 2.649 ± 0.065
3.529AspVal: 3.529 ± 0.084
0.682AspTrp: 0.682 ± 0.032
2.645AspTyr: 2.645 ± 0.071
0.0AspXaa: 0.0 ± 0.0
Glu
4.456GluAla: 4.456 ± 0.087
0.628GluCys: 0.628 ± 0.031
3.1GluAsp: 3.1 ± 0.076
4.802GluGlu: 4.802 ± 0.116
2.301GluPhe: 2.301 ± 0.056
3.971GluGly: 3.971 ± 0.086
1.351GluHis: 1.351 ± 0.044
4.402GluIle: 4.402 ± 0.09
4.961GluLys: 4.961 ± 0.107
6.079GluLeu: 6.079 ± 0.102
1.851GluMet: 1.851 ± 0.052
3.473GluAsn: 3.473 ± 0.072
1.679GluPro: 1.679 ± 0.051
3.007GluGln: 3.007 ± 0.07
3.191GluArg: 3.191 ± 0.075
3.0GluSer: 3.0 ± 0.072
3.344GluThr: 3.344 ± 0.069
4.039GluVal: 4.039 ± 0.08
0.732GluTrp: 0.732 ± 0.035
2.377GluTyr: 2.377 ± 0.062
0.0GluXaa: 0.0 ± 0.0
Phe
3.095PheAla: 3.095 ± 0.071
0.659PheCys: 0.659 ± 0.03
2.811PheAsp: 2.811 ± 0.055
2.539PheGlu: 2.539 ± 0.064
2.443PhePhe: 2.443 ± 0.071
3.007PheGly: 3.007 ± 0.074
0.815PheHis: 0.815 ± 0.034
3.689PheIle: 3.689 ± 0.083
3.05PheLys: 3.05 ± 0.071
4.05PheLeu: 4.05 ± 0.091
1.226PheMet: 1.226 ± 0.048
2.966PheAsn: 2.966 ± 0.066
1.467PhePro: 1.467 ± 0.049
1.225PheGln: 1.225 ± 0.039
1.726PheArg: 1.726 ± 0.047
3.517PheSer: 3.517 ± 0.075
2.911PheThr: 2.911 ± 0.074
3.024PheVal: 3.024 ± 0.065
0.49PheTrp: 0.49 ± 0.03
2.033PheTyr: 2.033 ± 0.058
0.0PheXaa: 0.0 ± 0.0
Gly
4.039GlyAla: 4.039 ± 0.072
0.786GlyCys: 0.786 ± 0.034
3.137GlyAsp: 3.137 ± 0.078
3.703GlyGlu: 3.703 ± 0.083
3.128GlyPhe: 3.128 ± 0.071
4.302GlyGly: 4.302 ± 0.102
1.217GlyHis: 1.217 ± 0.045
4.961GlyIle: 4.961 ± 0.093
5.157GlyLys: 5.157 ± 0.111
5.67GlyLeu: 5.67 ± 0.098
1.752GlyMet: 1.752 ± 0.051
3.318GlyAsn: 3.318 ± 0.071
1.061GlyPro: 1.061 ± 0.041
1.79GlyGln: 1.79 ± 0.054
2.574GlyArg: 2.574 ± 0.067
3.979GlySer: 3.979 ± 0.083
3.799GlyThr: 3.799 ± 0.082
4.833GlyVal: 4.833 ± 0.1
0.84GlyTrp: 0.84 ± 0.037
3.03GlyTyr: 3.03 ± 0.072
0.0GlyXaa: 0.0 ± 0.0
His
1.101HisAla: 1.101 ± 0.038
0.301HisCys: 0.301 ± 0.022
0.938HisAsp: 0.938 ± 0.038
0.963HisGlu: 0.963 ± 0.037
1.141HisPhe: 1.141 ± 0.042
1.097HisGly: 1.097 ± 0.044
0.541HisHis: 0.541 ± 0.027
1.47HisIle: 1.47 ± 0.044
1.162HisLys: 1.162 ± 0.042
1.972HisLeu: 1.972 ± 0.056
0.314HisMet: 0.314 ± 0.021
1.193HisAsn: 1.193 ± 0.046
0.938HisPro: 0.938 ± 0.034
0.769HisGln: 0.769 ± 0.035
0.805HisArg: 0.805 ± 0.034
1.25HisSer: 1.25 ± 0.043
1.041HisThr: 1.041 ± 0.035
1.023HisVal: 1.023 ± 0.038
0.219HisTrp: 0.219 ± 0.017
0.957HisTyr: 0.957 ± 0.04
0.0HisXaa: 0.0 ± 0.0
Ile
5.607IleAla: 5.607 ± 0.094
0.888IleCys: 0.888 ± 0.039
4.644IleAsp: 4.644 ± 0.088
5.033IleGlu: 5.033 ± 0.094
2.905IlePhe: 2.905 ± 0.078
4.546IleGly: 4.546 ± 0.096
1.303IleHis: 1.303 ± 0.048
5.285IleIle: 5.285 ± 0.113
5.515IleLys: 5.515 ± 0.111
6.158IleLeu: 6.158 ± 0.105
1.585IleMet: 1.585 ± 0.049
4.348IleAsn: 4.348 ± 0.094
2.943IlePro: 2.943 ± 0.063
2.395IleGln: 2.395 ± 0.06
2.941IleArg: 2.941 ± 0.07
4.864IleSer: 4.864 ± 0.094
4.725IleThr: 4.725 ± 0.091
4.675IleVal: 4.675 ± 0.088
0.574IleTrp: 0.574 ± 0.032
2.783IleTyr: 2.783 ± 0.069
0.0IleXaa: 0.0 ± 0.0
Lys
5.357LysAla: 5.357 ± 0.098
0.517LysCys: 0.517 ± 0.027
4.468LysAsp: 4.468 ± 0.086
6.457LysGlu: 6.457 ± 0.107
2.202LysPhe: 2.202 ± 0.057
4.938LysGly: 4.938 ± 0.091
1.386LysHis: 1.386 ± 0.044
4.77LysIle: 4.77 ± 0.099
5.721LysLys: 5.721 ± 0.1
5.719LysLeu: 5.719 ± 0.105
2.296LysMet: 2.296 ± 0.065
4.307LysAsn: 4.307 ± 0.083
2.276LysPro: 2.276 ± 0.056
3.309LysGln: 3.309 ± 0.074
3.357LysArg: 3.357 ± 0.069
3.722LysSer: 3.722 ± 0.077
4.238LysThr: 4.238 ± 0.097
4.929LysVal: 4.929 ± 0.095
0.851LysTrp: 0.851 ± 0.036
3.097LysTyr: 3.097 ± 0.064
0.0LysXaa: 0.0 ± 0.0
Leu
5.939LeuAla: 5.939 ± 0.101
1.256LeuCys: 1.256 ± 0.044
4.488LeuAsp: 4.488 ± 0.075
4.969LeuGlu: 4.969 ± 0.086
4.731LeuPhe: 4.731 ± 0.108
5.809LeuGly: 5.809 ± 0.112
1.928LeuHis: 1.928 ± 0.059
5.735LeuIle: 5.735 ± 0.105
6.979LeuLys: 6.979 ± 0.104
9.089LeuLeu: 9.089 ± 0.151
2.257LeuMet: 2.257 ± 0.057
5.366LeuAsn: 5.366 ± 0.11
3.841LeuPro: 3.841 ± 0.077
3.665LeuGln: 3.665 ± 0.074
4.02LeuArg: 4.02 ± 0.09
7.263LeuSer: 7.263 ± 0.113
5.414LeuThr: 5.414 ± 0.102
5.265LeuVal: 5.265 ± 0.106
1.031LeuTrp: 1.031 ± 0.041
3.757LeuTyr: 3.757 ± 0.087
0.0LeuXaa: 0.0 ± 0.0
Met
1.867MetAla: 1.867 ± 0.051
0.244MetCys: 0.244 ± 0.017
1.107MetAsp: 1.107 ± 0.041
1.344MetGlu: 1.344 ± 0.047
1.114MetPhe: 1.114 ± 0.042
1.692MetGly: 1.692 ± 0.052
0.477MetHis: 0.477 ± 0.026
1.729MetIle: 1.729 ± 0.046
2.293MetLys: 2.293 ± 0.061
2.421MetLeu: 2.421 ± 0.057
0.729MetMet: 0.729 ± 0.031
1.591MetAsn: 1.591 ± 0.047
1.145MetPro: 1.145 ± 0.04
1.163MetGln: 1.163 ± 0.04
1.22MetArg: 1.22 ± 0.04
1.648MetSer: 1.648 ± 0.048
1.274MetThr: 1.274 ± 0.041
1.499MetVal: 1.499 ± 0.048
0.219MetTrp: 0.219 ± 0.017
0.742MetTyr: 0.742 ± 0.029
0.0MetXaa: 0.0 ± 0.0
Asn
3.902AsnAla: 3.902 ± 0.085
0.534AsnCys: 0.534 ± 0.026
3.307AsnAsp: 3.307 ± 0.071
3.794AsnGlu: 3.794 ± 0.075
2.364AsnPhe: 2.364 ± 0.063
3.959AsnGly: 3.959 ± 0.102
1.051AsnHis: 1.051 ± 0.039
4.833AsnIle: 4.833 ± 0.098
4.654AsnLys: 4.654 ± 0.086
4.56AsnLeu: 4.56 ± 0.086
1.398AsnMet: 1.398 ± 0.041
4.097AsnAsn: 4.097 ± 0.086
2.449AsnPro: 2.449 ± 0.053
1.942AsnGln: 1.942 ± 0.06
2.36AsnArg: 2.36 ± 0.057
3.624AsnSer: 3.624 ± 0.077
3.387AsnThr: 3.387 ± 0.074
3.628AsnVal: 3.628 ± 0.072
0.642AsnTrp: 0.642 ± 0.033
2.533AsnTyr: 2.533 ± 0.068
0.0AsnXaa: 0.0 ± 0.0
Pro
2.036ProAla: 2.036 ± 0.059
0.324ProCys: 0.324 ± 0.022
1.737ProAsp: 1.737 ± 0.051
2.54ProGlu: 2.54 ± 0.065
1.889ProPhe: 1.889 ± 0.044
1.793ProGly: 1.793 ± 0.057
0.754ProHis: 0.754 ± 0.038
2.591ProIle: 2.591 ± 0.058
2.31ProLys: 2.31 ± 0.058
3.294ProLeu: 3.294 ± 0.068
0.828ProMet: 0.828 ± 0.033
2.122ProAsn: 2.122 ± 0.062
0.717ProPro: 0.717 ± 0.034
1.597ProGln: 1.597 ± 0.053
1.155ProArg: 1.155 ± 0.044
2.34ProSer: 2.34 ± 0.064
2.294ProThr: 2.294 ± 0.064
2.087ProVal: 2.087 ± 0.063
0.398ProTrp: 0.398 ± 0.024
1.595ProTyr: 1.595 ± 0.048
0.0ProXaa: 0.0 ± 0.0
Gln
2.269GlnAla: 2.269 ± 0.065
0.334GlnCys: 0.334 ± 0.02
1.652GlnAsp: 1.652 ± 0.046
2.463GlnGlu: 2.463 ± 0.067
1.477GlnPhe: 1.477 ± 0.044
2.151GlnGly: 2.151 ± 0.057
0.858GlnHis: 0.858 ± 0.035
2.459GlnIle: 2.459 ± 0.064
2.835GlnLys: 2.835 ± 0.071
3.841GlnLeu: 3.841 ± 0.092
1.031GlnMet: 1.031 ± 0.035
2.077GlnAsn: 2.077 ± 0.06
1.33GlnPro: 1.33 ± 0.044
1.965GlnGln: 1.965 ± 0.061
1.969GlnArg: 1.969 ± 0.054
2.093GlnSer: 2.093 ± 0.05
2.158GlnThr: 2.158 ± 0.06
2.131GlnVal: 2.131 ± 0.053
0.527GlnTrp: 0.527 ± 0.028
1.61GlnTyr: 1.61 ± 0.049
0.0GlnXaa: 0.0 ± 0.0
Arg
2.519ArgAla: 2.519 ± 0.068
0.406ArgCys: 0.406 ± 0.025
1.922ArgAsp: 1.922 ± 0.059
2.57ArgGlu: 2.57 ± 0.064
2.208ArgPhe: 2.208 ± 0.057
2.307ArgGly: 2.307 ± 0.055
0.838ArgHis: 0.838 ± 0.039
3.37ArgIle: 3.37 ± 0.074
3.272ArgLys: 3.272 ± 0.07
4.105ArgLeu: 4.105 ± 0.076
1.271ArgMet: 1.271 ± 0.048
2.547ArgAsn: 2.547 ± 0.068
1.362ArgPro: 1.362 ± 0.042
1.502ArgGln: 1.502 ± 0.047
1.784ArgArg: 1.784 ± 0.06
2.347ArgSer: 2.347 ± 0.058
2.364ArgThr: 2.364 ± 0.057
2.348ArgVal: 2.348 ± 0.058
0.599ArgTrp: 0.599 ± 0.033
2.095ArgTyr: 2.095 ± 0.069
0.0ArgXaa: 0.0 ± 0.0
Ser
4.081SerAla: 4.081 ± 0.072
0.892SerCys: 0.892 ± 0.04
3.263SerAsp: 3.263 ± 0.072
3.517SerGlu: 3.517 ± 0.066
3.706SerPhe: 3.706 ± 0.08
3.983SerGly: 3.983 ± 0.08
1.152SerHis: 1.152 ± 0.044
4.999SerIle: 4.999 ± 0.092
4.5SerLys: 4.5 ± 0.079
6.462SerLeu: 6.462 ± 0.123
1.558SerMet: 1.558 ± 0.052
3.541SerAsn: 3.541 ± 0.076
2.067SerPro: 2.067 ± 0.05
1.994SerGln: 1.994 ± 0.057
2.362SerArg: 2.362 ± 0.062
4.307SerSer: 4.307 ± 0.109
3.709SerThr: 3.709 ± 0.091
4.161SerVal: 4.161 ± 0.082
0.814SerTrp: 0.814 ± 0.034
2.844SerTyr: 2.844 ± 0.083
0.0SerXaa: 0.0 ± 0.0
Thr
4.074ThrAla: 4.074 ± 0.08
0.57ThrCys: 0.57 ± 0.032
2.992ThrAsp: 2.992 ± 0.072
3.284ThrGlu: 3.284 ± 0.064
2.975ThrPhe: 2.975 ± 0.067
3.742ThrGly: 3.742 ± 0.075
1.013ThrHis: 1.013 ± 0.041
4.82ThrIle: 4.82 ± 0.103
3.693ThrLys: 3.693 ± 0.064
6.056ThrLeu: 6.056 ± 0.086
1.28ThrMet: 1.28 ± 0.046
3.262ThrAsn: 3.262 ± 0.081
2.736ThrPro: 2.736 ± 0.064
2.104ThrGln: 2.104 ± 0.052
2.063ThrArg: 2.063 ± 0.055
3.833ThrSer: 3.833 ± 0.077
4.077ThrThr: 4.077 ± 0.095
2.794ThrVal: 2.794 ± 0.066
0.631ThrTrp: 0.631 ± 0.034
2.438ThrTyr: 2.438 ± 0.072
0.0ThrXaa: 0.0 ± 0.0
Val
4.411ValAla: 4.411 ± 0.075
0.852ValCys: 0.852 ± 0.038
3.634ValAsp: 3.634 ± 0.074
3.864ValGlu: 3.864 ± 0.082
2.797ValPhe: 2.797 ± 0.066
3.999ValGly: 3.999 ± 0.078
0.986ValHis: 0.986 ± 0.037
4.336ValIle: 4.336 ± 0.082
4.33ValLys: 4.33 ± 0.089
5.921ValLeu: 5.921 ± 0.107
1.536ValMet: 1.536 ± 0.051
3.367ValAsn: 3.367 ± 0.076
2.333ValPro: 2.333 ± 0.064
2.029ValGln: 2.029 ± 0.052
2.557ValArg: 2.557 ± 0.058
4.331ValSer: 4.331 ± 0.074
3.355ValThr: 3.355 ± 0.071
4.674ValVal: 4.674 ± 0.1
0.621ValTrp: 0.621 ± 0.028
2.594ValTyr: 2.594 ± 0.063
0.0ValXaa: 0.0 ± 0.0
Trp
0.693TrpAla: 0.693 ± 0.035
0.141TrpCys: 0.141 ± 0.015
0.581TrpAsp: 0.581 ± 0.031
0.592TrpGlu: 0.592 ± 0.031
0.565TrpPhe: 0.565 ± 0.025
0.813TrpGly: 0.813 ± 0.037
0.276TrpHis: 0.276 ± 0.022
0.729TrpIle: 0.729 ± 0.034
0.857TrpLys: 0.857 ± 0.039
1.142TrpLeu: 1.142 ± 0.046
0.332TrpMet: 0.332 ± 0.024
0.844TrpAsn: 0.844 ± 0.039
0.216TrpPro: 0.216 ± 0.02
0.519TrpGln: 0.519 ± 0.031
0.536TrpArg: 0.536 ± 0.026
0.642TrpSer: 0.642 ± 0.029
0.597TrpThr: 0.597 ± 0.038
0.68TrpVal: 0.68 ± 0.033
0.162TrpTrp: 0.162 ± 0.015
0.469TrpTyr: 0.469 ± 0.028
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.747TyrAla: 2.747 ± 0.066
0.595TyrCys: 0.595 ± 0.027
2.395TyrAsp: 2.395 ± 0.065
2.151TyrGlu: 2.151 ± 0.056
2.098TyrPhe: 2.098 ± 0.067
2.763TyrGly: 2.763 ± 0.074
0.879TyrHis: 0.879 ± 0.033
3.085TyrIle: 3.085 ± 0.073
2.946TyrLys: 2.946 ± 0.068
3.763TyrLeu: 3.763 ± 0.089
0.878TyrMet: 0.878 ± 0.036
2.915TyrAsn: 2.915 ± 0.075
1.652TyrPro: 1.652 ± 0.041
1.659TyrGln: 1.659 ± 0.061
2.014TyrArg: 2.014 ± 0.057
2.821TyrSer: 2.821 ± 0.075
2.583TyrThr: 2.583 ± 0.068
2.308TyrVal: 2.308 ± 0.063
0.526TyrTrp: 0.526 ± 0.032
2.047TyrTyr: 2.047 ± 0.067
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1947 proteins (703941 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski