Amino acid dipepetide frequency for Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.379AlaAla: 8.379 ± 0.059	1.135AlaCys: 1.135 ± 0.016	4.136AlaAsp: 4.136 ± 0.031	4.984AlaGlu: 4.984 ± 0.037	3.195AlaPhe: 3.195 ± 0.028	5.604AlaGly: 5.604 ± 0.034	1.687AlaHis: 1.687 ± 0.015	4.554AlaIle: 4.554 ± 0.032	4.175AlaLys: 4.175 ± 0.03	7.618AlaLeu: 7.618 ± 0.046	1.996AlaMet: 1.996 ± 0.018	2.95AlaAsn: 2.95 ± 0.023	4.533AlaPro: 4.533 ± 0.036	3.273AlaGln: 3.273 ± 0.024	4.478AlaArg: 4.478 ± 0.031	6.929AlaSer: 6.929 ± 0.04	5.176AlaThr: 5.176 ± 0.032	5.311AlaVal: 5.311 ± 0.038	1.243AlaTrp: 1.243 ± 0.016	2.186AlaTyr: 2.186 ± 0.018	0.0AlaXaa: 0.0 ± 0.0
Cys	0.936CysAla: 0.936 ± 0.013	0.264CysCys: 0.264 ± 0.009	0.728CysAsp: 0.728 ± 0.011	0.645CysGlu: 0.645 ± 0.013	0.594CysPhe: 0.594 ± 0.011	0.986CysGly: 0.986 ± 0.016	0.356CysHis: 0.356 ± 0.008	0.795CysIle: 0.795 ± 0.012	0.592CysLys: 0.592 ± 0.011	1.33CysLeu: 1.33 ± 0.018	0.303CysMet: 0.303 ± 0.007	0.49CysAsn: 0.49 ± 0.009	0.691CysPro: 0.691 ± 0.014	0.51CysGln: 0.51 ± 0.01	0.776CysArg: 0.776 ± 0.013	0.957CysSer: 0.957 ± 0.013	0.751CysThr: 0.751 ± 0.014	0.832CysVal: 0.832 ± 0.013	0.244CysTrp: 0.244 ± 0.006	0.407CysTyr: 0.407 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.649AspAla: 4.649 ± 0.031	0.683AspCys: 0.683 ± 0.011	4.284AspAsp: 4.284 ± 0.036	4.514AspGlu: 4.514 ± 0.034	2.319AspPhe: 2.319 ± 0.02	4.093AspGly: 4.093 ± 0.027	1.264AspHis: 1.264 ± 0.015	3.283AspIle: 3.283 ± 0.024	2.727AspLys: 2.727 ± 0.022	5.137AspLeu: 5.137 ± 0.032	1.358AspMet: 1.358 ± 0.014	2.05AspAsn: 2.05 ± 0.021	3.275AspPro: 3.275 ± 0.024	1.95AspGln: 1.95 ± 0.019	2.952AspArg: 2.952 ± 0.028	4.092AspSer: 4.092 ± 0.029	3.034AspThr: 3.034 ± 0.026	3.69AspVal: 3.69 ± 0.028	0.974AspTrp: 0.974 ± 0.013	1.674AspTyr: 1.674 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.451GluAla: 5.451 ± 0.043	0.67GluCys: 0.67 ± 0.011	4.144GluAsp: 4.144 ± 0.029	5.207GluGlu: 5.207 ± 0.046	2.013GluPhe: 2.013 ± 0.021	3.677GluGly: 3.677 ± 0.027	1.423GluHis: 1.423 ± 0.017	3.079GluIle: 3.079 ± 0.026	3.704GluLys: 3.704 ± 0.029	5.154GluLeu: 5.154 ± 0.037	1.476GluMet: 1.476 ± 0.017	2.336GluAsn: 2.336 ± 0.02	2.883GluPro: 2.883 ± 0.029	2.389GluGln: 2.389 ± 0.024	3.664GluArg: 3.664 ± 0.032	4.26GluSer: 4.26 ± 0.031	3.761GluThr: 3.761 ± 0.035	3.58GluVal: 3.58 ± 0.025	0.942GluTrp: 0.942 ± 0.013	1.691GluTyr: 1.691 ± 0.017	0.001GluXaa: 0.001 ± 0.0
Phe	3.072PheAla: 3.072 ± 0.022	0.606PheCys: 0.606 ± 0.011	2.358PheAsp: 2.358 ± 0.02	2.225PheGlu: 2.225 ± 0.022	1.741PhePhe: 1.741 ± 0.02	2.958PheGly: 2.958 ± 0.029	0.919PheHis: 0.919 ± 0.012	2.036PheIle: 2.036 ± 0.02	1.68PheLys: 1.68 ± 0.016	3.554PheLeu: 3.554 ± 0.026	0.876PheMet: 0.876 ± 0.012	1.564PheAsn: 1.564 ± 0.018	1.932PhePro: 1.932 ± 0.02	1.428PheGln: 1.428 ± 0.016	1.925PheArg: 1.925 ± 0.019	3.002PheSer: 3.002 ± 0.02	2.245PheThr: 2.245 ± 0.02	2.446PheVal: 2.446 ± 0.022	0.714PheTrp: 0.714 ± 0.011	1.167PheTyr: 1.167 ± 0.014	0.001PheXaa: 0.001 ± 0.0
Gly	5.185GlyAla: 5.185 ± 0.034	0.962GlyCys: 0.962 ± 0.014	3.703GlyAsp: 3.703 ± 0.027	3.493GlyGlu: 3.493 ± 0.025	2.956GlyPhe: 2.956 ± 0.022	5.36GlyGly: 5.36 ± 0.049	1.716GlyHis: 1.716 ± 0.017	3.761GlyIle: 3.761 ± 0.026	3.483GlyLys: 3.483 ± 0.03	6.184GlyLeu: 6.184 ± 0.036	1.607GlyMet: 1.607 ± 0.018	2.649GlyAsn: 2.649 ± 0.025	3.253GlyPro: 3.253 ± 0.028	2.563GlyGln: 2.563 ± 0.025	3.937GlyArg: 3.937 ± 0.026	5.6GlySer: 5.6 ± 0.041	3.952GlyThr: 3.952 ± 0.031	4.285GlyVal: 4.285 ± 0.029	1.243GlyTrp: 1.243 ± 0.014	2.222GlyTyr: 2.222 ± 0.025	0.001GlyXaa: 0.001 ± 0.0
His	1.74HisAla: 1.74 ± 0.018	0.345HisCys: 0.345 ± 0.008	1.398HisAsp: 1.398 ± 0.016	1.378HisGlu: 1.378 ± 0.015	0.955HisPhe: 0.955 ± 0.012	1.737HisGly: 1.737 ± 0.02	0.834HisHis: 0.834 ± 0.017	1.265HisIle: 1.265 ± 0.014	0.996HisLys: 0.996 ± 0.014	2.241HisLeu: 2.241 ± 0.025	0.516HisMet: 0.516 ± 0.009	0.875HisAsn: 0.875 ± 0.012	1.497HisPro: 1.497 ± 0.018	0.985HisGln: 0.985 ± 0.014	1.447HisArg: 1.447 ± 0.018	1.722HisSer: 1.722 ± 0.018	1.192HisThr: 1.192 ± 0.014	1.454HisVal: 1.454 ± 0.015	0.379HisTrp: 0.379 ± 0.009	0.723HisTyr: 0.723 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.395IleAla: 4.395 ± 0.03	0.834IleCys: 0.834 ± 0.012	3.071IleAsp: 3.071 ± 0.021	3.061IleGlu: 3.061 ± 0.023	2.12IlePhe: 2.12 ± 0.021	3.429IleGly: 3.429 ± 0.027	1.258IleHis: 1.258 ± 0.014	2.806IleIle: 2.806 ± 0.027	2.425IleLys: 2.425 ± 0.02	4.733IleLeu: 4.733 ± 0.031	1.122IleMet: 1.122 ± 0.015	1.994IleAsn: 1.994 ± 0.019	3.068IlePro: 3.068 ± 0.022	1.985IleGln: 1.985 ± 0.018	2.851IleArg: 2.851 ± 0.021	3.966IleSer: 3.966 ± 0.028	3.028IleThr: 3.028 ± 0.024	3.312IleVal: 3.312 ± 0.027	0.834IleTrp: 0.834 ± 0.013	1.495IleTyr: 1.495 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.445LysAla: 4.445 ± 0.035	0.574LysCys: 0.574 ± 0.011	3.114LysAsp: 3.114 ± 0.026	3.416LysGlu: 3.416 ± 0.025	1.564LysPhe: 1.564 ± 0.017	3.142LysGly: 3.142 ± 0.03	1.2LysHis: 1.2 ± 0.016	2.391LysIle: 2.391 ± 0.025	3.398LysLys: 3.398 ± 0.034	4.249LysLeu: 4.249 ± 0.026	1.051LysMet: 1.051 ± 0.014	1.899LysAsn: 1.899 ± 0.023	2.897LysPro: 2.897 ± 0.027	1.878LysGln: 1.878 ± 0.017	3.292LysArg: 3.292 ± 0.027	3.58LysSer: 3.58 ± 0.025	3.117LysThr: 3.117 ± 0.024	2.959LysVal: 2.959 ± 0.023	0.763LysTrp: 0.763 ± 0.011	1.451LysTyr: 1.451 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.709LeuAla: 7.709 ± 0.04	1.263LeuCys: 1.263 ± 0.016	5.234LeuAsp: 5.234 ± 0.034	5.504LeuGlu: 5.504 ± 0.038	3.399LeuPhe: 3.399 ± 0.025	6.02LeuGly: 6.02 ± 0.034	2.139LeuHis: 2.139 ± 0.019	4.288LeuIle: 4.288 ± 0.026	4.325LeuLys: 4.325 ± 0.027	8.17LeuLeu: 8.17 ± 0.053	1.888LeuMet: 1.888 ± 0.021	3.214LeuAsn: 3.214 ± 0.025	5.2LeuPro: 5.2 ± 0.031	3.743LeuGln: 3.743 ± 0.029	5.418LeuArg: 5.418 ± 0.034	7.108LeuSer: 7.108 ± 0.038	4.847LeuThr: 4.847 ± 0.029	5.51LeuVal: 5.51 ± 0.031	1.281LeuTrp: 1.281 ± 0.014	2.389LeuTyr: 2.389 ± 0.022	0.003LeuXaa: 0.003 ± 0.001
Met	2.322MetAla: 2.322 ± 0.021	0.272MetCys: 0.272 ± 0.007	1.267MetAsp: 1.267 ± 0.013	1.259MetGlu: 1.259 ± 0.016	0.801MetPhe: 0.801 ± 0.011	1.509MetGly: 1.509 ± 0.019	0.492MetHis: 0.492 ± 0.009	1.111MetIle: 1.111 ± 0.016	1.095MetLys: 1.095 ± 0.012	1.896MetLeu: 1.896 ± 0.02	0.644MetMet: 0.644 ± 0.012	0.847MetAsn: 0.847 ± 0.013	1.318MetPro: 1.318 ± 0.016	0.851MetGln: 0.851 ± 0.012	1.225MetArg: 1.225 ± 0.013	1.991MetSer: 1.991 ± 0.017	1.377MetThr: 1.377 ± 0.015	1.341MetVal: 1.341 ± 0.018	0.281MetTrp: 0.281 ± 0.006	0.541MetTyr: 0.541 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.097AsnAla: 3.097 ± 0.023	0.497AsnCys: 0.497 ± 0.011	2.076AsnAsp: 2.076 ± 0.019	2.122AsnGlu: 2.122 ± 0.019	1.433AsnPhe: 1.433 ± 0.016	3.024AsnGly: 3.024 ± 0.028	0.878AsnHis: 0.878 ± 0.014	2.165AsnIle: 2.165 ± 0.019	1.785AsnLys: 1.785 ± 0.018	3.35AsnLeu: 3.35 ± 0.023	0.928AsnMet: 0.928 ± 0.014	1.606AsnAsn: 1.606 ± 0.018	2.379AsnPro: 2.379 ± 0.022	1.383AsnGln: 1.383 ± 0.017	1.94AsnArg: 1.94 ± 0.021	2.793AsnSer: 2.793 ± 0.021	2.261AsnThr: 2.261 ± 0.019	2.307AsnVal: 2.307 ± 0.019	0.645AsnTrp: 0.645 ± 0.009	1.089AsnTyr: 1.089 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	4.717ProAla: 4.717 ± 0.036	0.555ProCys: 0.555 ± 0.009	3.284ProAsp: 3.284 ± 0.023	3.988ProGlu: 3.988 ± 0.031	2.08ProPhe: 2.08 ± 0.021	3.848ProGly: 3.848 ± 0.031	1.243ProHis: 1.243 ± 0.016	2.541ProIle: 2.541 ± 0.02	2.833ProLys: 2.833 ± 0.027	4.499ProLeu: 4.499 ± 0.03	1.107ProMet: 1.107 ± 0.013	2.175ProAsn: 2.175 ± 0.018	4.385ProPro: 4.385 ± 0.062	2.379ProGln: 2.379 ± 0.028	3.201ProArg: 3.201 ± 0.027	5.43ProSer: 5.43 ± 0.037	3.735ProThr: 3.735 ± 0.034	3.506ProVal: 3.506 ± 0.029	0.814ProTrp: 0.814 ± 0.012	1.482ProTyr: 1.482 ± 0.019	0.001ProXaa: 0.001 ± 0.0
Gln	3.429GlnAla: 3.429 ± 0.026	0.466GlnCys: 0.466 ± 0.01	2.237GlnAsp: 2.237 ± 0.02	2.403GlnGlu: 2.403 ± 0.023	1.294GlnPhe: 1.294 ± 0.014	2.503GlnGly: 2.503 ± 0.021	1.048GlnHis: 1.048 ± 0.017	1.871GlnIle: 1.871 ± 0.019	1.965GlnLys: 1.965 ± 0.019	3.389GlnLeu: 3.389 ± 0.03	0.895GlnMet: 0.895 ± 0.015	1.56GlnAsn: 1.56 ± 0.016	2.468GlnPro: 2.468 ± 0.031	2.227GlnGln: 2.227 ± 0.038	2.461GlnArg: 2.461 ± 0.021	2.947GlnSer: 2.947 ± 0.026	2.256GlnThr: 2.256 ± 0.021	2.27GlnVal: 2.27 ± 0.02	0.617GlnTrp: 0.617 ± 0.01	1.162GlnTyr: 1.162 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.288ArgAla: 4.288 ± 0.031	0.724ArgCys: 0.724 ± 0.013	3.364ArgAsp: 3.364 ± 0.027	3.555ArgGlu: 3.555 ± 0.033	2.122ArgPhe: 2.122 ± 0.02	3.52ArgGly: 3.52 ± 0.026	1.516ArgHis: 1.516 ± 0.017	2.882ArgIle: 2.882 ± 0.022	3.25ArgLys: 3.25 ± 0.026	5.297ArgLeu: 5.297 ± 0.032	1.279ArgMet: 1.279 ± 0.015	2.228ArgAsn: 2.228 ± 0.019	3.268ArgPro: 3.268 ± 0.026	2.475ArgGln: 2.475 ± 0.024	4.67ArgArg: 4.67 ± 0.041	4.416ArgSer: 4.416 ± 0.035	3.09ArgThr: 3.09 ± 0.026	3.24ArgVal: 3.24 ± 0.025	0.961ArgTrp: 0.961 ± 0.011	1.664ArgTyr: 1.664 ± 0.019	0.001ArgXaa: 0.001 ± 0.0
Ser	6.114SerAla: 6.114 ± 0.036	0.966SerCys: 0.966 ± 0.017	4.313SerAsp: 4.313 ± 0.032	4.123SerGlu: 4.123 ± 0.027	3.084SerPhe: 3.084 ± 0.025	5.395SerGly: 5.395 ± 0.04	1.916SerHis: 1.916 ± 0.019	4.144SerIle: 4.144 ± 0.023	3.83SerLys: 3.83 ± 0.026	7.038SerLeu: 7.038 ± 0.039	1.757SerMet: 1.757 ± 0.019	2.969SerAsn: 2.969 ± 0.023	5.021SerPro: 5.021 ± 0.041	3.244SerGln: 3.244 ± 0.024	4.671SerArg: 4.671 ± 0.031	7.935SerSer: 7.935 ± 0.055	5.225SerThr: 5.225 ± 0.041	4.497SerVal: 4.497 ± 0.029	1.244SerTrp: 1.244 ± 0.013	2.135SerTyr: 2.135 ± 0.019	0.001SerXaa: 0.001 ± 0.0
Thr	5.061ThrAla: 5.061 ± 0.036	0.828ThrCys: 0.828 ± 0.015	2.916ThrAsp: 2.916 ± 0.023	3.293ThrGlu: 3.293 ± 0.031	2.316ThrPhe: 2.316 ± 0.02	4.181ThrGly: 4.181 ± 0.03	1.233ThrHis: 1.233 ± 0.014	3.277ThrIle: 3.277 ± 0.03	2.91ThrLys: 2.91 ± 0.028	5.154ThrLeu: 5.154 ± 0.032	1.23ThrMet: 1.23 ± 0.014	2.191ThrAsn: 2.191 ± 0.02	4.056ThrPro: 4.056 ± 0.037	2.13ThrGln: 2.13 ± 0.018	3.062ThrArg: 3.062 ± 0.024	5.118ThrSer: 5.118 ± 0.04	4.272ThrThr: 4.272 ± 0.06	3.748ThrVal: 3.748 ± 0.034	0.958ThrTrp: 0.958 ± 0.013	1.689ThrTyr: 1.689 ± 0.016	0.001ThrXaa: 0.001 ± 0.0
Val	5.158ValAla: 5.158 ± 0.031	0.871ValCys: 0.871 ± 0.014	3.698ValAsp: 3.698 ± 0.027	3.842ValGlu: 3.842 ± 0.029	2.598ValPhe: 2.598 ± 0.023	3.96ValGly: 3.96 ± 0.029	1.368ValHis: 1.368 ± 0.016	3.187ValIle: 3.187 ± 0.024	3.088ValLys: 3.088 ± 0.024	5.503ValLeu: 5.503 ± 0.032	1.354ValMet: 1.354 ± 0.014	2.284ValAsn: 2.284 ± 0.021	3.503ValPro: 3.503 ± 0.024	2.341ValGln: 2.341 ± 0.019	3.209ValArg: 3.209 ± 0.023	4.595ValSer: 4.595 ± 0.032	3.65ValThr: 3.65 ± 0.035	4.211ValVal: 4.211 ± 0.037	0.908ValTrp: 0.908 ± 0.013	1.795ValTyr: 1.795 ± 0.017	0.001ValXaa: 0.001 ± 0.0
Trp	1.237TrpAla: 1.237 ± 0.014	0.217TrpCys: 0.217 ± 0.006	0.971TrpAsp: 0.971 ± 0.013	0.901TrpGlu: 0.901 ± 0.014	0.631TrpPhe: 0.631 ± 0.011	1.026TrpGly: 1.026 ± 0.015	0.39TrpHis: 0.39 ± 0.007	0.885TrpIle: 0.885 ± 0.013	0.888TrpLys: 0.888 ± 0.013	1.47TrpLeu: 1.47 ± 0.017	0.403TrpMet: 0.403 ± 0.008	0.687TrpAsn: 0.687 ± 0.011	0.695TrpPro: 0.695 ± 0.011	0.604TrpGln: 0.604 ± 0.01	0.961TrpArg: 0.961 ± 0.013	1.141TrpSer: 1.141 ± 0.016	1.019TrpThr: 1.019 ± 0.014	0.956TrpVal: 0.956 ± 0.013	0.308TrpTrp: 0.308 ± 0.008	0.476TrpTyr: 0.476 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.159TyrAla: 2.159 ± 0.02	0.454TyrCys: 0.454 ± 0.009	1.704TyrAsp: 1.704 ± 0.017	1.592TyrGlu: 1.592 ± 0.017	1.233TyrPhe: 1.233 ± 0.014	2.143TyrGly: 2.143 ± 0.023	0.8TyrHis: 0.8 ± 0.011	1.465TyrIle: 1.465 ± 0.016	1.23TyrLys: 1.23 ± 0.016	2.682TyrLeu: 2.682 ± 0.023	0.649TyrMet: 0.649 ± 0.011	1.189TyrAsn: 1.189 ± 0.015	1.481TyrPro: 1.481 ± 0.018	1.13TyrGln: 1.13 ± 0.017	1.665TyrArg: 1.665 ± 0.017	2.043TyrSer: 2.043 ± 0.02	1.635TyrThr: 1.635 ± 0.016	1.67TyrVal: 1.67 ± 0.017	0.513TyrTrp: 0.513 ± 0.01	0.978TyrTyr: 0.978 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.003XaaArg: 0.003 ± 0.001	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	2.751XaaXaa: 2.751 ± 0.477

Statistics based on 14157 proteins (6288100 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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